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Overview

ID MAG01701
Name HKD1_bin.12
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Vicinamibacteria
Order Vicinamibacterales
Family UBA2999
Genus DATNBT01
Species
Assembly information
Completeness (%) 99.07
Contamination (%) 9.2
GC content (%) 69.0
N50 (bp) 49,080
Genome size (bp) 6,204,127

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes5103

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1012893_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 3.023e-307 954.0
HKD1_k127_1012893_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 1.756e-290 948.0
HKD1_k127_1012893_10 HpcH/HpaI aldolase/citrate lyase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 465.0
HKD1_k127_1012893_11 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 462.0
HKD1_k127_1012893_12 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 446.0
HKD1_k127_1012893_13 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 425.0
HKD1_k127_1012893_14 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 385.0
HKD1_k127_1012893_15 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 370.0
HKD1_k127_1012893_16 Sulfotransferase K01014 - 2.8.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 364.0
HKD1_k127_1012893_17 glucose sorbosone K00117,K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 320.0
HKD1_k127_1012893_18 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 312.0
HKD1_k127_1012893_19 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003403 301.0
HKD1_k127_1012893_2 electron transport chain K00347,K03614 - 1.6.5.8 1.026e-254 807.0
HKD1_k127_1012893_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001284 280.0
HKD1_k127_1012893_21 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004373 250.0
HKD1_k127_1012893_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001152 241.0
HKD1_k127_1012893_23 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000002089 268.0
HKD1_k127_1012893_24 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002039 244.0
HKD1_k127_1012893_25 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000009622 255.0
HKD1_k127_1012893_26 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000002073 227.0
HKD1_k127_1012893_27 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000001165 224.0
HKD1_k127_1012893_28 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000002917 213.0
HKD1_k127_1012893_29 - - - - 0.0000000000000000000000000000000000000000000000000003799 198.0
HKD1_k127_1012893_3 ASPIC and UnbV - - - 5.235e-229 726.0
HKD1_k127_1012893_30 Ferredoxin K04755 - - 0.000000000000000000000000000000000000000000000000008745 182.0
HKD1_k127_1012893_31 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000001291 192.0
HKD1_k127_1012893_32 - - - - 0.0000000000000000000000000000000000000000638 155.0
HKD1_k127_1012893_33 - - - - 0.000000000000000000000000000000000000001425 161.0
HKD1_k127_1012893_34 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000163 164.0
HKD1_k127_1012893_35 - - - - 0.000000000000000000000000000000000001268 153.0
HKD1_k127_1012893_36 - - - - 0.000000000000000000000000000000000004149 150.0
HKD1_k127_1012893_37 transcriptional regulator - - - 0.00000000000000000000000000000000000913 159.0
HKD1_k127_1012893_38 short chain amide porin - - - 0.00000000000000000000000000000000001148 140.0
HKD1_k127_1012893_39 - - - - 0.0000000000000000000000000000000002731 144.0
HKD1_k127_1012893_4 asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 622.0
HKD1_k127_1012893_40 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000004492 141.0
HKD1_k127_1012893_41 - - - - 0.00000000000000000000000000001233 129.0
HKD1_k127_1012893_42 DinB family - - - 0.0000000000000000000000000001317 122.0
HKD1_k127_1012893_43 transport - - - 0.000000000000000000000001119 123.0
HKD1_k127_1012893_44 Translation Initiation Factor K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000005012 106.0
HKD1_k127_1012893_45 - - - - 0.00000000000000000000001475 107.0
HKD1_k127_1012893_46 - - - - 0.0000000000000009321 82.0
HKD1_k127_1012893_47 PHP-associated - - - 0.00000000002102 76.0
HKD1_k127_1012893_48 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000939 64.0
HKD1_k127_1012893_5 protein-containing complex disassembly K02837,K07133 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 589.0
HKD1_k127_1012893_6 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 577.0
HKD1_k127_1012893_7 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 514.0
HKD1_k127_1012893_8 PQQ-like domain K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 526.0
HKD1_k127_1012893_9 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 512.0
HKD1_k127_1031266_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1380.0
HKD1_k127_1031266_1 lipopolysaccharide transport K22110 - - 0.0 1349.0
HKD1_k127_1031266_10 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 602.0
HKD1_k127_1031266_11 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 535.0
HKD1_k127_1031266_12 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 528.0
HKD1_k127_1031266_13 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 520.0
HKD1_k127_1031266_14 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 525.0
HKD1_k127_1031266_15 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 500.0
HKD1_k127_1031266_16 PQQ-like domain K00114,K20937 - 1.1.2.8,1.1.5.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 510.0
HKD1_k127_1031266_17 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 494.0
HKD1_k127_1031266_18 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 508.0
HKD1_k127_1031266_19 Transport and Golgi organisation 2 K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 477.0
HKD1_k127_1031266_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1159.0
HKD1_k127_1031266_20 transcription factor binding K15836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 467.0
HKD1_k127_1031266_21 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 407.0
HKD1_k127_1031266_22 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 425.0
HKD1_k127_1031266_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 403.0
HKD1_k127_1031266_24 SMART Phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 392.0
HKD1_k127_1031266_25 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 384.0
HKD1_k127_1031266_26 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 392.0
HKD1_k127_1031266_27 beta-lactamase activity K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 369.0
HKD1_k127_1031266_28 XdhC Rossmann domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 340.0
HKD1_k127_1031266_29 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009839 327.0
HKD1_k127_1031266_3 Ammonium transporter K03320 - - 4.08e-259 812.0
HKD1_k127_1031266_30 PFAM ThiJ PfpI domain protein K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 319.0
HKD1_k127_1031266_31 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008887 282.0
HKD1_k127_1031266_32 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001669 287.0
HKD1_k127_1031266_33 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004319 268.0
HKD1_k127_1031266_34 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001329 266.0
HKD1_k127_1031266_35 molybdopterin cofactor binding K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003041 264.0
HKD1_k127_1031266_36 domain, Protein K15125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006053 287.0
HKD1_k127_1031266_37 COGs COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000007811 255.0
HKD1_k127_1031266_38 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001043 259.0
HKD1_k127_1031266_39 Bacterial low temperature requirement A protein (LtrA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006784 260.0
HKD1_k127_1031266_4 choline dehydrogenase activity - - - 2.663e-253 803.0
HKD1_k127_1031266_40 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006945 263.0
HKD1_k127_1031266_41 Metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000307 244.0
HKD1_k127_1031266_42 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000273 238.0
HKD1_k127_1031266_43 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003271 251.0
HKD1_k127_1031266_44 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000002918 237.0
HKD1_k127_1031266_45 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000002606 226.0
HKD1_k127_1031266_46 Chlorophyllase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000002544 244.0
HKD1_k127_1031266_47 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000005642 219.0
HKD1_k127_1031266_48 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000000000000000000000000000000000000116 214.0
HKD1_k127_1031266_49 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000001855 203.0
HKD1_k127_1031266_5 Amylo-alpha-1,6-glucosidase - - - 1.589e-239 762.0
HKD1_k127_1031266_50 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000000000000000000004858 201.0
HKD1_k127_1031266_51 His Kinase A (phosphoacceptor - - - 0.0000000000000000000000000000000000000000000000000000007242 215.0
HKD1_k127_1031266_52 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000009831 194.0
HKD1_k127_1031266_53 - - - - 0.0000000000000000000000000000000000000000000000000006532 199.0
HKD1_k127_1031266_54 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000002672 185.0
HKD1_k127_1031266_55 - - - - 0.00000000000000000000000000000000000000000000000003315 194.0
HKD1_k127_1031266_56 cytochrome K17230 - - 0.00000000000000000000000000000000000000000000000008818 187.0
HKD1_k127_1031266_57 - - - - 0.000000000000000000000000000000000000000000000002192 179.0
HKD1_k127_1031266_58 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000006312 191.0
HKD1_k127_1031266_59 carbon monoxide dehydrogenase K09386 - - 0.00000000000000000000000000000000000000000000002089 179.0
HKD1_k127_1031266_6 amino acid - - - 1.713e-237 751.0
HKD1_k127_1031266_60 translation initiation factor activity K02004,K10939,K12257,K14393 - - 0.0000000000000000000000000000000000000000000002717 188.0
HKD1_k127_1031266_61 Transport and Golgi organisation 2 K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000001033 168.0
HKD1_k127_1031266_62 Thiamine-binding protein - - - 0.000000000000000000000000000000000000000006096 158.0
HKD1_k127_1031266_63 - - - - 0.00000000000000000000000000000000000000001348 158.0
HKD1_k127_1031266_64 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000001729 150.0
HKD1_k127_1031266_65 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000002155 157.0
HKD1_k127_1031266_66 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000002591 157.0
HKD1_k127_1031266_67 - - - - 0.0000000000000000000000000000000000004621 143.0
HKD1_k127_1031266_68 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000003952 138.0
HKD1_k127_1031266_69 - - - - 0.0000000000000000000000000000000002399 147.0
HKD1_k127_1031266_7 Protein tyrosine kinase K12132 - 2.7.11.1 5.615e-208 683.0
HKD1_k127_1031266_70 - - - - 0.00000000000000000000000000000002176 141.0
HKD1_k127_1031266_71 PFAM DsrE DsrF-like family K09004 - - 0.0000000000000000000000000000002529 128.0
HKD1_k127_1031266_72 - - - - 0.0000000000000000000000000000217 134.0
HKD1_k127_1031266_73 conserved repeat domain protein - - - 0.0000000000000000000000001018 126.0
HKD1_k127_1031266_74 Protein of unknown function (DUF1810) - - - 0.000000000000000000000003504 108.0
HKD1_k127_1031266_75 - - - - 0.00000000000000000000001878 113.0
HKD1_k127_1031266_76 - - - - 0.0000000000000000000002531 113.0
HKD1_k127_1031266_77 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000003346 112.0
HKD1_k127_1031266_78 DinB family - - - 0.00000000000000000002214 98.0
HKD1_k127_1031266_79 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000003898 98.0
HKD1_k127_1031266_8 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 5.271e-198 649.0
HKD1_k127_1031266_80 GtrA-like protein - - - 0.000000000000000002626 98.0
HKD1_k127_1031266_81 Cupin 2, conserved barrel domain protein K11312 - - 0.0000000000000007596 89.0
HKD1_k127_1031266_82 - - - - 0.00000000000001809 76.0
HKD1_k127_1031266_85 Cupin 2, conserved barrel domain protein - - - 0.00000000008584 74.0
HKD1_k127_1031266_86 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.000000000856 72.0
HKD1_k127_1031266_87 Domain of unknown function (DUF4382) - - - 0.000000001313 68.0
HKD1_k127_1031266_88 ig-like, plexins, transcription factors - - - 0.0000000324 64.0
HKD1_k127_1031266_9 Involved in the tonB-independent uptake of proteins - - - 5.033e-196 643.0
HKD1_k127_1031266_90 - - - - 0.000001784 56.0
HKD1_k127_1031266_92 Membrane - - - 0.0001107 49.0
HKD1_k127_1031266_94 - - - - 0.0003077 53.0
HKD1_k127_1031266_95 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0007752 52.0
HKD1_k127_1066609_0 Phosphoribosyl transferase domain K07100 - - 4.582e-248 786.0
HKD1_k127_1066609_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 580.0
HKD1_k127_1066609_2 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000001169 269.0
HKD1_k127_1066609_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000384 93.0
HKD1_k127_1066609_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000006405 74.0
HKD1_k127_1066609_5 Integral membrane protein TerC family - - - 0.0000000000144 67.0
HKD1_k127_1066609_6 Pkd domain containing protein - - - 0.00006391 55.0
HKD1_k127_1067452_0 Carboxypeptidase regulatory-like domain - - - 2.413e-227 718.0
HKD1_k127_1067452_1 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 503.0
HKD1_k127_1067452_10 - - - - 0.000000000000000000000000000000000000000000000001046 187.0
HKD1_k127_1067452_11 - - - - 0.000000000000000000000000000000000000000001191 163.0
HKD1_k127_1067452_12 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000004524 150.0
HKD1_k127_1067452_13 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000001768 133.0
HKD1_k127_1067452_14 - - - - 0.000000000000000000000000001757 131.0
HKD1_k127_1067452_15 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000003578 109.0
HKD1_k127_1067452_16 Zinc-binding dehydrogenase K19745 - - 0.00000000000000000000001672 101.0
HKD1_k127_1067452_17 - - - - 0.00000000000001018 87.0
HKD1_k127_1067452_18 - - - - 0.0000000000001038 77.0
HKD1_k127_1067452_2 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 444.0
HKD1_k127_1067452_20 - - - - 0.0000000000001936 78.0
HKD1_k127_1067452_21 - - - - 0.00000000001141 79.0
HKD1_k127_1067452_22 - - - - 0.0000000000194 70.0
HKD1_k127_1067452_23 - - - - 0.0000000002904 67.0
HKD1_k127_1067452_25 PFAM Cytochrome c, class I - - - 0.0000002447 61.0
HKD1_k127_1067452_27 Copper binding periplasmic protein CusF K07152 - - 0.00001984 53.0
HKD1_k127_1067452_28 - - - - 0.00002069 51.0
HKD1_k127_1067452_29 Protein of unknown function (DUF3341) - - - 0.00002255 57.0
HKD1_k127_1067452_3 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 327.0
HKD1_k127_1067452_4 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008721 287.0
HKD1_k127_1067452_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000029 236.0
HKD1_k127_1067452_6 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000001028 216.0
HKD1_k127_1067452_7 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000185 216.0
HKD1_k127_1067452_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000003788 198.0
HKD1_k127_1067452_9 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000003082 204.0
HKD1_k127_1082096_0 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003483 289.0
HKD1_k127_1082096_1 Domain of unknown function (DUF4124) - - - 0.00000000000686 72.0
HKD1_k127_1082096_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000002684 51.0
HKD1_k127_1113299_0 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 489.0
HKD1_k127_1113299_1 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01032 - 2.8.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 451.0
HKD1_k127_1113299_10 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000241 241.0
HKD1_k127_1113299_11 Domain of unknown function (DUF1835) - - - 0.000000000000000000000000000000000000000000000000000000001443 228.0
HKD1_k127_1113299_12 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000008842 171.0
HKD1_k127_1113299_13 - - - - 0.000000000000000000000000000000000000000000004728 176.0
HKD1_k127_1113299_14 - - - - 0.00000000000000000000000000000000000001876 158.0
HKD1_k127_1113299_15 Beta-lactamase - - - 0.000000000000000000000000000000000000428 151.0
HKD1_k127_1113299_16 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000007221 148.0
HKD1_k127_1113299_17 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000002938 130.0
HKD1_k127_1113299_18 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000008905 123.0
HKD1_k127_1113299_19 - - - - 0.00000000000000000000006959 111.0
HKD1_k127_1113299_2 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 438.0
HKD1_k127_1113299_20 - - - - 0.00000000000000000000007344 101.0
HKD1_k127_1113299_21 DoxX K16937 - 1.8.5.2 0.0000000000000000000000989 103.0
HKD1_k127_1113299_22 Domain of unknown function (DUF4390) - - - 0.00002114 56.0
HKD1_k127_1113299_3 Short chain fatty acid transporter K02106 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 413.0
HKD1_k127_1113299_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 398.0
HKD1_k127_1113299_5 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 367.0
HKD1_k127_1113299_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 351.0
HKD1_k127_1113299_7 COG0685 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000879 280.0
HKD1_k127_1113299_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002701 267.0
HKD1_k127_1113299_9 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000004265 238.0
HKD1_k127_1129364_0 4Fe-4S dicluster domain K00184 - - 0.0 1043.0
HKD1_k127_1129364_1 M61 glycyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 529.0
HKD1_k127_1129364_2 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 486.0
HKD1_k127_1129364_3 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 305.0
HKD1_k127_1129364_4 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 323.0
HKD1_k127_1129364_5 Thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000007614 188.0
HKD1_k127_1129364_7 protein import - - - 0.0000000000001358 85.0
HKD1_k127_1200593_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 5.665e-264 820.0
HKD1_k127_1200593_1 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 445.0
HKD1_k127_1200593_2 Osmosensitive K channel His kinase sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 357.0
HKD1_k127_1200593_3 Met-10+ like-protein - - - 0.0000000000000000000000000000000000000000000000000000007649 214.0
HKD1_k127_1200593_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000002789 196.0
HKD1_k127_1200593_6 Regulatory protein - - - 0.0000000000000002119 89.0
HKD1_k127_1200593_7 - - - - 0.0003504 43.0
HKD1_k127_1216831_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 3.785e-297 925.0
HKD1_k127_1216831_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 2.155e-282 881.0
HKD1_k127_1216831_10 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 521.0
HKD1_k127_1216831_11 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 495.0
HKD1_k127_1216831_12 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 493.0
HKD1_k127_1216831_13 alcohol dehydrogenase K00001,K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 478.0
HKD1_k127_1216831_14 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 467.0
HKD1_k127_1216831_15 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K02805 GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 453.0
HKD1_k127_1216831_16 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13017 - 1.17.1.1,2.6.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 442.0
HKD1_k127_1216831_17 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 434.0
HKD1_k127_1216831_18 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 424.0
HKD1_k127_1216831_19 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 432.0
HKD1_k127_1216831_2 nodulation K00612 - - 3.147e-264 826.0
HKD1_k127_1216831_20 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 411.0
HKD1_k127_1216831_21 Putative zinc binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 407.0
HKD1_k127_1216831_22 NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 400.0
HKD1_k127_1216831_23 pfam abc K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 381.0
HKD1_k127_1216831_24 Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 360.0
HKD1_k127_1216831_25 NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 349.0
HKD1_k127_1216831_26 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 366.0
HKD1_k127_1216831_27 methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 321.0
HKD1_k127_1216831_28 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 359.0
HKD1_k127_1216831_29 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 319.0
HKD1_k127_1216831_3 PFAM oxidoreductase - - - 5.964e-261 830.0
HKD1_k127_1216831_30 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 314.0
HKD1_k127_1216831_31 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 295.0
HKD1_k127_1216831_32 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001025 294.0
HKD1_k127_1216831_33 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003666 279.0
HKD1_k127_1216831_34 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001107 262.0
HKD1_k127_1216831_35 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002579 259.0
HKD1_k127_1216831_36 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001943 277.0
HKD1_k127_1216831_37 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001795 273.0
HKD1_k127_1216831_38 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002803 247.0
HKD1_k127_1216831_39 Methyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003854 249.0
HKD1_k127_1216831_4 Transferase hexapeptide repeat containing protein K13018 - 2.3.1.201 6.82e-198 631.0
HKD1_k127_1216831_40 ABC transporter, ATP-binding protein K01990,K09691,K09693 - 3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000395 256.0
HKD1_k127_1216831_41 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003294 252.0
HKD1_k127_1216831_42 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001782 257.0
HKD1_k127_1216831_43 PFAM NAD dependent epimerase dehydratase family K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000002638 233.0
HKD1_k127_1216831_44 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000005769 242.0
HKD1_k127_1216831_45 WbqC-like protein family - - - 0.00000000000000000000000000000000000000000000000000000000000001728 229.0
HKD1_k127_1216831_46 phosphoglycolate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004609 219.0
HKD1_k127_1216831_47 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000007126 226.0
HKD1_k127_1216831_48 - - - - 0.000000000000000000000000000000000000000000000000000000000001142 237.0
HKD1_k127_1216831_49 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000001964 225.0
HKD1_k127_1216831_5 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 628.0
HKD1_k127_1216831_50 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000001631 222.0
HKD1_k127_1216831_51 - - - - 0.00000000000000000000000000000000000000000000000000000001488 220.0
HKD1_k127_1216831_52 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000007943 213.0
HKD1_k127_1216831_53 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000000000000000000000000000000000000000000000000001319 203.0
HKD1_k127_1216831_54 PFAM ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000001407 202.0
HKD1_k127_1216831_55 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000001761 190.0
HKD1_k127_1216831_56 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000001149 180.0
HKD1_k127_1216831_57 pfam nudix - - - 0.00000000000000000000000000000000000000000000004965 176.0
HKD1_k127_1216831_58 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000004791 176.0
HKD1_k127_1216831_59 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000002539 177.0
HKD1_k127_1216831_6 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 586.0
HKD1_k127_1216831_60 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000003363 171.0
HKD1_k127_1216831_61 Glycosyl transferases group 1 K06338 - - 0.00000000000000000000000000000000000000000659 177.0
HKD1_k127_1216831_62 acetyltransferase - - - 0.00000000000000000000000000000000000000001057 167.0
HKD1_k127_1216831_63 SIS domain K03271 - 5.3.1.28 0.00000000000000000000000000000000000000003965 160.0
HKD1_k127_1216831_64 GDP-mannose mannosyl hydrolase activity K01515 - 3.6.1.13 0.0000000000000000000000000000000000000001163 160.0
HKD1_k127_1216831_65 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000006888 163.0
HKD1_k127_1216831_66 Winged helix-turn-helix DNA-binding - - - 0.0000000000000000000000000000000000933 141.0
HKD1_k127_1216831_67 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000007366 146.0
HKD1_k127_1216831_68 deacetylase K06986 - - 0.000000000000000000000000000002394 130.0
HKD1_k127_1216831_69 Methyltransferase domain - - - 0.0000000000000000000000000000637 129.0
HKD1_k127_1216831_7 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 546.0
HKD1_k127_1216831_70 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000002867 132.0
HKD1_k127_1216831_71 Polysaccharide biosynthesis protein K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000000000001058 112.0
HKD1_k127_1216831_72 acetyltransferase, isoleucine patch superfamily K21379 - 2.3.1.209 0.00000000000000000005161 105.0
HKD1_k127_1216831_73 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000004501 86.0
HKD1_k127_1216831_74 PFAM Methyltransferase domain - - - 0.00000000001088 74.0
HKD1_k127_1216831_75 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000001431 77.0
HKD1_k127_1216831_76 methyltransferase - - - 0.00000000007568 72.0
HKD1_k127_1216831_77 - - - - 0.0000000001824 64.0
HKD1_k127_1216831_78 PFAM glycosyl transferase family 39 - - - 0.000000001407 71.0
HKD1_k127_1216831_79 - - - - 0.00000006554 65.0
HKD1_k127_1216831_8 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009066 538.0
HKD1_k127_1216831_80 - - - - 0.0000001392 59.0
HKD1_k127_1216831_81 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00007147 56.0
HKD1_k127_1216831_82 GDSL-like Lipase/Acylhydrolase family - - - 0.0002712 52.0
HKD1_k127_1216831_9 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 505.0
HKD1_k127_1225002_0 Phosphoribulokinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 473.0
HKD1_k127_1225002_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000001037 145.0
HKD1_k127_1225002_2 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000722 117.0
HKD1_k127_1433951_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 8.253e-298 939.0
HKD1_k127_1433951_1 A circularly permuted ATPgrasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 607.0
HKD1_k127_1433951_2 - - - - 0.0000000000000000001387 93.0
HKD1_k127_1449782_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 2.696e-252 790.0
HKD1_k127_1449782_1 PFAM Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 392.0
HKD1_k127_1449782_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 393.0
HKD1_k127_1449782_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.000000000000000000000000000000002881 130.0
HKD1_k127_15504_0 Radical SAM - - - 0.0 1112.0
HKD1_k127_15504_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 2.013e-297 921.0
HKD1_k127_15504_10 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 343.0
HKD1_k127_15504_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 328.0
HKD1_k127_15504_12 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 319.0
HKD1_k127_15504_13 ATPase activity K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 320.0
HKD1_k127_15504_14 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 303.0
HKD1_k127_15504_15 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 302.0
HKD1_k127_15504_16 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 293.0
HKD1_k127_15504_17 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 305.0
HKD1_k127_15504_18 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003661 271.0
HKD1_k127_15504_19 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000001414 267.0
HKD1_k127_15504_2 Amino acid permease K03294 - - 8.012e-214 673.0
HKD1_k127_15504_20 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001637 248.0
HKD1_k127_15504_21 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000009911 212.0
HKD1_k127_15504_22 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000004127 200.0
HKD1_k127_15504_23 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000639 220.0
HKD1_k127_15504_24 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000855 187.0
HKD1_k127_15504_25 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000005636 168.0
HKD1_k127_15504_26 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000000000000000000008104 165.0
HKD1_k127_15504_27 NUDIX domain - - - 0.0000000000000000000000000000000000000005656 160.0
HKD1_k127_15504_28 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.000000000000000000000000000000000000003003 157.0
HKD1_k127_15504_29 - K01992,K19341 - - 0.00000000000000000000000000006937 126.0
HKD1_k127_15504_3 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 612.0
HKD1_k127_15504_30 ABC-2 family transporter protein K01992 - - 0.000000000000000000000921 111.0
HKD1_k127_15504_31 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000002972 104.0
HKD1_k127_15504_32 - - - - 0.000000000000000000007894 106.0
HKD1_k127_15504_33 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000000003127 96.0
HKD1_k127_15504_34 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.0000000000000001333 83.0
HKD1_k127_15504_35 deoxyhypusine monooxygenase activity - - - 0.000000000000005429 89.0
HKD1_k127_15504_36 oxidoreductase activity - - - 0.000000002035 70.0
HKD1_k127_15504_37 shape-determining protein MreD K03571 - - 0.000001004 61.0
HKD1_k127_15504_38 - - - - 0.000002668 59.0
HKD1_k127_15504_39 type IV pilus assembly PilZ - - - 0.0008041 47.0
HKD1_k127_15504_4 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 512.0
HKD1_k127_15504_5 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 507.0
HKD1_k127_15504_6 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 496.0
HKD1_k127_15504_7 PFAM Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 471.0
HKD1_k127_15504_8 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 447.0
HKD1_k127_15504_9 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 423.0
HKD1_k127_1554866_0 PQQ-like domain K00114 - 1.1.2.8 2.874e-265 836.0
HKD1_k127_1554866_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 1.202e-221 704.0
HKD1_k127_1554866_2 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 606.0
HKD1_k127_1554866_3 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008993 547.0
HKD1_k127_1554866_4 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 430.0
HKD1_k127_1554866_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000003701 194.0
HKD1_k127_1554866_6 tail collar domain protein K06237 - - 0.00000000000000000000000005407 121.0
HKD1_k127_1554866_7 Pfam:N_methyl_2 - - - 0.00000000000000007719 88.0
HKD1_k127_1554866_8 - - - - 0.0003317 53.0
HKD1_k127_1558899_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000003119 155.0
HKD1_k127_1558899_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 0.0000000000000000000000001605 114.0
HKD1_k127_1558899_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000001539 92.0
HKD1_k127_1558899_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000221 93.0
HKD1_k127_1570137_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 8.457e-218 690.0
HKD1_k127_1570137_1 elongation factor G K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 297.0
HKD1_k127_1570137_2 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004694 279.0
HKD1_k127_1570137_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001264 281.0
HKD1_k127_1570137_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000456 271.0
HKD1_k127_1570137_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005499 269.0
HKD1_k127_1570137_6 Yip1 domain - - - 0.000000000000001419 89.0
HKD1_k127_1570137_7 - - - - 0.0001169 54.0
HKD1_k127_1570137_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.0004188 49.0
HKD1_k127_1633079_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 380.0
HKD1_k127_1633079_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 311.0
HKD1_k127_1633079_2 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000001441 102.0
HKD1_k127_1633079_3 Methyltransferase domain - - - 0.00000000000000000009646 90.0
HKD1_k127_1644152_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 383.0
HKD1_k127_1644152_1 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000463 275.0
HKD1_k127_1644152_10 PFAM methyltransferase - - - 0.00000298 59.0
HKD1_k127_1644152_11 Xylose isomerase-like TIM barrel - - - 0.0001196 55.0
HKD1_k127_1644152_2 D-glycero-D-manno-heptose 7-phosphate metabolic process K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000006419 263.0
HKD1_k127_1644152_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000000000000000411 249.0
HKD1_k127_1644152_4 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000001405 201.0
HKD1_k127_1644152_5 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000003393 183.0
HKD1_k127_1644152_6 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000005506 173.0
HKD1_k127_1644152_7 UDP-galactopyranose mutase - - - 0.000000000000000000000000000000000001297 154.0
HKD1_k127_1644152_8 DinB family - - - 0.0000000000000000000000000000003024 130.0
HKD1_k127_1644152_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000001538 96.0
HKD1_k127_1670321_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 2.725e-263 818.0
HKD1_k127_1670321_1 PFAM Rh family protein ammonium transporter K03320 - - 1.291e-234 735.0
HKD1_k127_1670321_10 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000003234 152.0
HKD1_k127_1670321_11 Flavin reductase like domain - - - 0.0000000000000000000000000000000004598 151.0
HKD1_k127_1670321_12 TonB-dependent receptor - - - 0.00000000000000000000000009218 126.0
HKD1_k127_1670321_13 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000001147 101.0
HKD1_k127_1670321_14 BON domain - - - 0.0000000000000000000001222 112.0
HKD1_k127_1670321_15 Dehydrogenase K00117 - 1.1.5.2 0.000000000000000001371 100.0
HKD1_k127_1670321_16 Domain of unknown function (DUF4915) - - - 0.0000000000135 79.0
HKD1_k127_1670321_17 Pfam:N_methyl_2 - - - 0.00000000009135 65.0
HKD1_k127_1670321_18 serine threonine protein kinase - - - 0.000000007189 66.0
HKD1_k127_1670321_19 Domain of unknown function (DUF4440) - - - 0.0002972 50.0
HKD1_k127_1670321_2 PFAM Ribonuclease II K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 563.0
HKD1_k127_1670321_20 - - - - 0.0007664 51.0
HKD1_k127_1670321_3 PQQ-like domain K17760 - 1.1.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 502.0
HKD1_k127_1670321_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 368.0
HKD1_k127_1670321_5 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 357.0
HKD1_k127_1670321_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 348.0
HKD1_k127_1670321_7 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004922 297.0
HKD1_k127_1670321_8 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000001803 196.0
HKD1_k127_1670321_9 manganese ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000003433 184.0
HKD1_k127_1683191_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 3.395e-255 798.0
HKD1_k127_1686275_0 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 553.0
HKD1_k127_1686275_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008876 281.0
HKD1_k127_1686275_2 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.000000000003708 78.0
HKD1_k127_1686275_3 nuclease activity - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.00000007446 61.0
HKD1_k127_1775939_0 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 293.0
HKD1_k127_1775939_1 imidazolonepropionase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001017 249.0
HKD1_k127_1775939_2 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000000000000001714 191.0
HKD1_k127_1872364_0 Cytochrome c-type biogenesis protein K02198 - - 1.308e-235 754.0
HKD1_k127_1872364_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 634.0
HKD1_k127_1872364_10 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 357.0
HKD1_k127_1872364_11 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 351.0
HKD1_k127_1872364_12 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 346.0
HKD1_k127_1872364_13 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 329.0
HKD1_k127_1872364_14 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 333.0
HKD1_k127_1872364_15 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 309.0
HKD1_k127_1872364_16 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002084 290.0
HKD1_k127_1872364_17 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000006602 280.0
HKD1_k127_1872364_18 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005275 266.0
HKD1_k127_1872364_19 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000004282 252.0
HKD1_k127_1872364_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 621.0
HKD1_k127_1872364_20 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005111 233.0
HKD1_k127_1872364_21 O-acyltransferase activity K00661 - 2.3.1.79 0.000000000000000000000000000000000000000000000000000000000000003662 228.0
HKD1_k127_1872364_22 TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000006142 235.0
HKD1_k127_1872364_23 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000002657 214.0
HKD1_k127_1872364_24 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000008889 193.0
HKD1_k127_1872364_25 - - - - 0.000000000000000000000000000000000000000000000000001615 201.0
HKD1_k127_1872364_26 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000007027 194.0
HKD1_k127_1872364_27 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000001579 180.0
HKD1_k127_1872364_28 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000009301 177.0
HKD1_k127_1872364_29 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000005033 160.0
HKD1_k127_1872364_3 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 481.0
HKD1_k127_1872364_30 ABC transporter K02193 - 3.6.3.41 0.000000000000000000000000000000000001019 160.0
HKD1_k127_1872364_31 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000003481 141.0
HKD1_k127_1872364_32 Nodulation protein S (NodS) K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000002082 133.0
HKD1_k127_1872364_33 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.0000000000000000000000000000003612 127.0
HKD1_k127_1872364_34 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000004054 141.0
HKD1_k127_1872364_35 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000002953 125.0
HKD1_k127_1872364_36 oligosaccharyl transferase activity K00721 - 2.4.1.83 0.0000000000000000000000000000128 135.0
HKD1_k127_1872364_37 PFAM Uncharacterised protein family (UPF0104) K07027 - - 0.00000000000000000000000000007027 128.0
HKD1_k127_1872364_38 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000003995 112.0
HKD1_k127_1872364_39 - - - - 0.000000000000000000000009406 106.0
HKD1_k127_1872364_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 471.0
HKD1_k127_1872364_40 Methyltransferase domain - - - 0.00000000000000000000004943 110.0
HKD1_k127_1872364_41 - - - - 0.0000000000000001091 90.0
HKD1_k127_1872364_42 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000006721 80.0
HKD1_k127_1872364_43 - - - - 0.00000000001117 79.0
HKD1_k127_1872364_45 - - - - 0.0000000001735 70.0
HKD1_k127_1872364_46 - - - - 0.00000005442 63.0
HKD1_k127_1872364_47 - - - - 0.00003797 55.0
HKD1_k127_1872364_48 Protein of unknown function (DUF721) - - - 0.0002306 49.0
HKD1_k127_1872364_5 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 474.0
HKD1_k127_1872364_6 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 425.0
HKD1_k127_1872364_7 WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 426.0
HKD1_k127_1872364_8 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 366.0
HKD1_k127_1872364_9 PFAM NAD-dependent epimerase dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 357.0
HKD1_k127_1916201_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 1.379e-280 876.0
HKD1_k127_1916201_1 DNA topological change K03168 - 5.99.1.2 6.309e-248 789.0
HKD1_k127_1916201_10 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 423.0
HKD1_k127_1916201_11 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 408.0
HKD1_k127_1916201_12 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 356.0
HKD1_k127_1916201_13 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 317.0
HKD1_k127_1916201_14 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000002953 271.0
HKD1_k127_1916201_15 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001365 263.0
HKD1_k127_1916201_16 MafB19-like deaminase K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000000000000000009339 239.0
HKD1_k127_1916201_17 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001104 237.0
HKD1_k127_1916201_18 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000001035 201.0
HKD1_k127_1916201_19 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000005296 191.0
HKD1_k127_1916201_2 LVIVD repeat - - - 1.724e-234 730.0
HKD1_k127_1916201_20 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000004408 172.0
HKD1_k127_1916201_21 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000001033 168.0
HKD1_k127_1916201_22 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000002867 183.0
HKD1_k127_1916201_23 - - - - 0.000000000000000000000000000000000000000001522 177.0
HKD1_k127_1916201_24 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000002477 164.0
HKD1_k127_1916201_25 Ankyrin repeat K06867 - - 0.000000000000000000000000000000000000000689 167.0
HKD1_k127_1916201_26 Acyltransferase family - - - 0.000000000000000000000000000000000000001075 169.0
HKD1_k127_1916201_27 DinB superfamily K07552 - - 0.00000000000000000000000000000000000004583 148.0
HKD1_k127_1916201_28 TPM domain K06872 - - 0.00000000000000000000000000000000007691 145.0
HKD1_k127_1916201_29 integral membrane protein - - - 0.000000000000000000000000002316 127.0
HKD1_k127_1916201_3 PQQ-like domain K00114 - 1.1.2.8 9.722e-202 641.0
HKD1_k127_1916201_30 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000006754 121.0
HKD1_k127_1916201_32 Protein of unknown function (DUF2752) - - - 0.000000000000004194 79.0
HKD1_k127_1916201_33 - - - - 0.000000001651 66.0
HKD1_k127_1916201_34 Acetyltransferase (GNAT) domain K00657,K00663 - 2.3.1.57,2.3.1.82 0.000000002784 68.0
HKD1_k127_1916201_35 light absorption - - - 0.0000402 53.0
HKD1_k127_1916201_4 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 522.0
HKD1_k127_1916201_5 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 497.0
HKD1_k127_1916201_6 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 511.0
HKD1_k127_1916201_7 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 434.0
HKD1_k127_1916201_8 PFAM FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 428.0
HKD1_k127_1916201_9 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 428.0
HKD1_k127_2012388_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 548.0
HKD1_k127_2015505_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 429.0
HKD1_k127_2015505_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005074 275.0
HKD1_k127_2015505_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0003208 52.0
HKD1_k127_2015505_3 SMART Tetratricopeptide - - - 0.0003259 51.0
HKD1_k127_2018381_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 4.474e-208 667.0
HKD1_k127_2018381_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 4.224e-207 659.0
HKD1_k127_2018381_10 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 308.0
HKD1_k127_2018381_11 Dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 298.0
HKD1_k127_2018381_12 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000004943 253.0
HKD1_k127_2018381_13 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000005921 240.0
HKD1_k127_2018381_14 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000006578 227.0
HKD1_k127_2018381_15 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000027 213.0
HKD1_k127_2018381_16 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000001458 218.0
HKD1_k127_2018381_17 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000001985 201.0
HKD1_k127_2018381_18 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000004098 198.0
HKD1_k127_2018381_19 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000001603 193.0
HKD1_k127_2018381_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 533.0
HKD1_k127_2018381_20 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000002747 188.0
HKD1_k127_2018381_21 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000004064 190.0
HKD1_k127_2018381_22 Peptidase family M50 K06402 - - 0.0000000000000000000000000000000000000000000001274 175.0
HKD1_k127_2018381_23 - - - - 0.0000000000000000000000000000000000000000000002862 181.0
HKD1_k127_2018381_24 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000005063 169.0
HKD1_k127_2018381_25 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000001624 184.0
HKD1_k127_2018381_26 - - - - 0.00000000000000000000000000000000000000118 163.0
HKD1_k127_2018381_27 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000000000000003473 138.0
HKD1_k127_2018381_29 - - - - 0.0000000000000000000000000001105 134.0
HKD1_k127_2018381_3 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 516.0
HKD1_k127_2018381_30 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000005552 115.0
HKD1_k127_2018381_31 - - - - 0.0000000000000000000000001457 111.0
HKD1_k127_2018381_32 - - - - 0.0000000000000000009163 93.0
HKD1_k127_2018381_33 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000004201 83.0
HKD1_k127_2018381_34 oxidoreductase activity - - - 0.0000000001762 74.0
HKD1_k127_2018381_4 ATPase domain of DNA mismatch repair MUTS family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 512.0
HKD1_k127_2018381_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 509.0
HKD1_k127_2018381_6 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 473.0
HKD1_k127_2018381_7 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 396.0
HKD1_k127_2018381_8 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 364.0
HKD1_k127_2018381_9 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 365.0
HKD1_k127_2029535_0 ATP-grasp domain K01905,K22224 - 6.2.1.13 3.181e-290 917.0
HKD1_k127_2029535_1 Phosphate acyltransferases - - - 3.335e-240 775.0
HKD1_k127_2029535_10 AMP binding - - - 0.0000000000000000000000000000000000000000000000000265 198.0
HKD1_k127_2029535_11 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000000000000000000000000000001253 170.0
HKD1_k127_2029535_12 - - - - 0.00000000000000000000000000000000000000000001354 170.0
HKD1_k127_2029535_13 - - - - 0.000000000000000000000000000000000000000000483 165.0
HKD1_k127_2029535_15 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000003072 166.0
HKD1_k127_2029535_16 - - - - 0.0000000000000000000000000000000000000004337 162.0
HKD1_k127_2029535_17 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000005001 111.0
HKD1_k127_2029535_18 Protein of unknown function, DUF481 K07283 - - 0.000000000006426 76.0
HKD1_k127_2029535_19 PFAM Ethyl tert-butyl ether degradation EthD - - - 0.00000000001112 69.0
HKD1_k127_2029535_2 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 595.0
HKD1_k127_2029535_20 peptidyl-tyrosine sulfation - - - 0.000007945 55.0
HKD1_k127_2029535_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 480.0
HKD1_k127_2029535_4 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 469.0
HKD1_k127_2029535_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006032 273.0
HKD1_k127_2029535_6 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001869 261.0
HKD1_k127_2029535_7 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002479 263.0
HKD1_k127_2029535_8 - - - - 0.00000000000000000000000000000000000000000000000000000000002507 210.0
HKD1_k127_2029535_9 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000002873 206.0
HKD1_k127_2032336_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 5.014e-211 670.0
HKD1_k127_2032336_1 Aspartate alanine antiporter family protein 1 K07085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 516.0
HKD1_k127_2032336_2 Belongs to the asparaginase 1 family K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 294.0
HKD1_k127_2032336_3 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006908 276.0
HKD1_k127_2032336_4 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000001784 200.0
HKD1_k127_2032336_5 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000003035 166.0
HKD1_k127_2032336_6 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000003172 130.0
HKD1_k127_2032336_7 - - - - 0.000000000000000000000001165 110.0
HKD1_k127_2033099_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 4.631e-236 739.0
HKD1_k127_2033099_1 belongs to the iron- containing alcohol dehydrogenase family K04072 - 1.1.1.1,1.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 319.0
HKD1_k127_2040761_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 531.0
HKD1_k127_2040761_1 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003521 252.0
HKD1_k127_2042190_0 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 460.0
HKD1_k127_2042190_1 Gram-negative porin - - - 0.0000000000000000000000000000000000000000000000001276 191.0
HKD1_k127_206518_0 pyridine nucleotide-disulphide oxidoreductase K17218 GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0042802,GO:0044237,GO:0045333,GO:0055114 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 579.0
HKD1_k127_206518_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 472.0
HKD1_k127_206518_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 459.0
HKD1_k127_206518_3 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 353.0
HKD1_k127_206518_4 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 327.0
HKD1_k127_206518_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 288.0
HKD1_k127_206518_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000222 174.0
HKD1_k127_206518_7 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000001056 170.0
HKD1_k127_206518_8 Preprotein translocase SecG subunit K03075 - - 0.000000000000003721 81.0
HKD1_k127_2069522_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K03737 - 1.2.7.1 0.0 1923.0
HKD1_k127_2069522_1 Sugar (and other) transporter K08195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 402.0
HKD1_k127_2069522_2 4-oxalomesaconate hydratase K03392,K10220 - 4.1.1.45,4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 326.0
HKD1_k127_2069522_3 ribonuclease inhibitor activity K10218 - 4.1.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 315.0
HKD1_k127_2069522_4 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04099,K04101 - 1.13.11.57,1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 311.0
HKD1_k127_2069522_5 Domain of unknown function (DUF1932) - - - 0.00000000000000000000000000000000000000000000000000000000001354 217.0
HKD1_k127_2069522_6 - - - - 0.0000000000000000000000000000000342 144.0
HKD1_k127_2069522_7 - - - - 0.000000000000000000000000000003892 124.0
HKD1_k127_2069522_8 - - - - 0.00000000000000000000000000004574 126.0
HKD1_k127_2069522_9 - - - - 0.00000000000000000000000000005068 129.0
HKD1_k127_2077073_0 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 499.0
HKD1_k127_2077073_1 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003676 287.0
HKD1_k127_2077073_2 - - - - 0.0000000000000000000000000000000000000000000001613 180.0
HKD1_k127_2077073_3 - - - - 0.0000000000000000000001631 111.0
HKD1_k127_2077073_4 - - - - 0.0000000000000000000003772 106.0
HKD1_k127_2109803_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 3.332e-204 662.0
HKD1_k127_2109803_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K14986 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 370.0
HKD1_k127_2109803_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000777 315.0
HKD1_k127_2109803_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 305.0
HKD1_k127_2109803_4 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001466 269.0
HKD1_k127_2109803_5 - - - - 0.0000000000000000000000000000000004411 136.0
HKD1_k127_2109803_6 - - - - 0.0000000000000000002444 94.0
HKD1_k127_2109803_7 protein transport - - - 0.00000000000000004649 83.0
HKD1_k127_2109803_8 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000009762 94.0
HKD1_k127_2130924_1 Endoribonuclease L-PSP - - - 0.00000000002368 63.0
HKD1_k127_2130924_2 Pyrrolo-quinoline quinone beta-propeller repeat - - - 0.00001771 57.0
HKD1_k127_2143482_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.064e-203 650.0
HKD1_k127_2143482_1 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000003272 155.0
HKD1_k127_2171251_0 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 360.0
HKD1_k127_2171251_1 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004496 265.0
HKD1_k127_2175045_0 secretion system protein K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 548.0
HKD1_k127_2175045_1 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 424.0
HKD1_k127_2175045_10 AAA domain K02282 - - 0.000000000000000000000000000000000000001115 165.0
HKD1_k127_2175045_11 Histidine kinase - - - 0.00000000000000000000000000000000000001065 164.0
HKD1_k127_2175045_12 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000008309 138.0
HKD1_k127_2175045_13 Smr domain - - - 0.0000000000000000000000000002478 117.0
HKD1_k127_2175045_14 Bacterial DNA-binding protein K03530 - - 0.0000000000000000005715 91.0
HKD1_k127_2175045_15 Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.0000000000000003665 85.0
HKD1_k127_2175045_16 PFAM TadE family protein - - - 0.0000000000000005489 85.0
HKD1_k127_2175045_17 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000004222 87.0
HKD1_k127_2175045_18 PAP2 superfamily - - - 0.00000000000001452 87.0
HKD1_k127_2175045_19 Zinc carboxypeptidase - - - 0.00000000005596 66.0
HKD1_k127_2175045_2 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 318.0
HKD1_k127_2175045_20 Flp Fap pilin component K02651 - - 0.000002366 53.0
HKD1_k127_2175045_3 type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000006091 236.0
HKD1_k127_2175045_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000006265 240.0
HKD1_k127_2175045_5 PFAM Type II secretion system F K12510 - - 0.00000000000000000000000000000000000000000000000000000004044 219.0
HKD1_k127_2175045_6 von Willebrand factor type A domain - - - 0.000000000000000000000000000000000000000000000008183 190.0
HKD1_k127_2175045_7 IMG reference gene - - - 0.000000000000000000000000000000000000000000002192 188.0
HKD1_k127_2175045_8 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000002858 164.0
HKD1_k127_2175045_9 PFAM SAF domain K02279 - - 0.00000000000000000000000000000000000000009704 161.0
HKD1_k127_2182519_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 554.0
HKD1_k127_2182519_1 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 435.0
HKD1_k127_2182519_2 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000003031 157.0
HKD1_k127_2182519_3 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000003567 144.0
HKD1_k127_2182519_4 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 K18715 GO:0000054,GO:0000055,GO:0000056,GO:0000166,GO:0000774,GO:0003674,GO:0003712,GO:0003714,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005643,GO:0006403,GO:0006405,GO:0006406,GO:0006606,GO:0006607,GO:0006611,GO:0006810,GO:0006886,GO:0006913,GO:0006996,GO:0006997,GO:0008104,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010556,GO:0010558,GO:0010605,GO:0012505,GO:0015031,GO:0015833,GO:0015931,GO:0016020,GO:0016021,GO:0016043,GO:0016973,GO:0017038,GO:0017076,GO:0019219,GO:0019222,GO:0022613,GO:0030234,GO:0030554,GO:0031081,GO:0031224,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031503,GO:0031967,GO:0031975,GO:0032991,GO:0033036,GO:0033365,GO:0033750,GO:0034504,GO:0034613,GO:0034629,GO:0036094,GO:0042254,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044446,GO:0044464,GO:0044613,GO:0044614,GO:0045184,GO:0045934,GO:0046907,GO:0048519,GO:0048523,GO:0050657,GO:0050658,GO:0050789,GO:0050790,GO:0050794,GO:0051028,GO:0051168,GO:0051169,GO:0051170,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051236,GO:0051252,GO:0051253,GO:0051640,GO:0051641,GO:0051649,GO:0051656,GO:0051664,GO:0051668,GO:0060255,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070727,GO:0071166,GO:0071426,GO:0071427,GO:0071428,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0080090,GO:0097064,GO:0097159,GO:0098772,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2001141 - 0.0001283 47.0
HKD1_k127_2199361_0 Glucodextranase, domain N K01178 - 3.2.1.3 9.604e-312 975.0
HKD1_k127_2199361_1 E1-E2 ATPase K01535 - 3.6.3.6 6.539e-289 907.0
HKD1_k127_2199361_10 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 326.0
HKD1_k127_2199361_11 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 306.0
HKD1_k127_2199361_12 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007527 288.0
HKD1_k127_2199361_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001202 282.0
HKD1_k127_2199361_14 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008771 256.0
HKD1_k127_2199361_15 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004313 239.0
HKD1_k127_2199361_16 HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000001832 235.0
HKD1_k127_2199361_17 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000006101 207.0
HKD1_k127_2199361_18 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000073 203.0
HKD1_k127_2199361_19 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000003424 208.0
HKD1_k127_2199361_2 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 567.0
HKD1_k127_2199361_20 DoxX - - - 0.000000000000000000000000000000000000000000000000000001764 207.0
HKD1_k127_2199361_21 bacterial OsmY and nodulation domain - - - 0.00000000000000000000000000000000000000000000000000111 193.0
HKD1_k127_2199361_22 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000002312 179.0
HKD1_k127_2199361_23 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000002443 167.0
HKD1_k127_2199361_24 Glyoxalase-like domain K01759 - 4.4.1.5 0.000000000000000000000000000000000000000002472 159.0
HKD1_k127_2199361_25 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000001874 175.0
HKD1_k127_2199361_26 Two component transcriptional regulator, winged helix family K07657 - - 0.000000000000000000000000000000000000002927 156.0
HKD1_k127_2199361_27 Universal stress protein family - - - 0.000000000000000000000000000000000000003688 151.0
HKD1_k127_2199361_28 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000000000003794 147.0
HKD1_k127_2199361_29 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000041 141.0
HKD1_k127_2199361_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 547.0
HKD1_k127_2199361_31 NADPH-quinone reductase (modulator of drug activity B) - - - 0.000000000000000000000000000004173 128.0
HKD1_k127_2199361_32 - - - - 0.00000000000000000000000000006829 124.0
HKD1_k127_2199361_33 - - - - 0.000000000000000000000001855 107.0
HKD1_k127_2199361_34 RHS Repeat - - - 0.00000000000000000000001046 115.0
HKD1_k127_2199361_35 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000001845 106.0
HKD1_k127_2199361_36 Sulfatase - - - 0.00000000000000000002681 107.0
HKD1_k127_2199361_37 - - - - 0.00000000000000000003542 91.0
HKD1_k127_2199361_39 Membrane - - - 0.0000000000000003995 83.0
HKD1_k127_2199361_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 523.0
HKD1_k127_2199361_40 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000006872 76.0
HKD1_k127_2199361_41 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000001346 79.0
HKD1_k127_2199361_42 response regulator K07720 - - 0.00000000008929 71.0
HKD1_k127_2199361_43 dksA traR - - - 0.00000000009183 68.0
HKD1_k127_2199361_44 Phage derived protein Gp49-like (DUF891) - - - 0.0000000001983 63.0
HKD1_k127_2199361_45 PFAM blue (type 1) copper domain protein - - - 0.0000000004591 67.0
HKD1_k127_2199361_46 AntiSigma factor - - - 0.000000003945 69.0
HKD1_k127_2199361_48 Copper binding proteins, plastocyanin/azurin family - - - 0.000000095 59.0
HKD1_k127_2199361_49 Regulatory protein - - - 0.000000477 56.0
HKD1_k127_2199361_5 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 486.0
HKD1_k127_2199361_50 Phage Tail Collar Domain - - - 0.00000319 57.0
HKD1_k127_2199361_51 NAD(P)H dehydrogenase - - - 0.000005505 56.0
HKD1_k127_2199361_52 COG1405 Transcription initiation factor TFIIIB, Brf1 subunit Transcription initiation factor TFIIB - - - 0.0001765 53.0
HKD1_k127_2199361_6 Bacterial regulatory protein, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 475.0
HKD1_k127_2199361_7 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 436.0
HKD1_k127_2199361_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 377.0
HKD1_k127_2199361_9 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 366.0
HKD1_k127_2204233_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 1.14e-322 1012.0
HKD1_k127_2204233_1 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K04099 - 1.13.11.57 1.156e-218 687.0
HKD1_k127_2204233_10 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000218 259.0
HKD1_k127_2204233_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004239 246.0
HKD1_k127_2204233_12 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000003692 153.0
HKD1_k127_2204233_13 - - - - 0.00000000000000000000000000000000002661 139.0
HKD1_k127_2204233_14 GYD domain - - - 0.000000000000000000000000000000006323 130.0
HKD1_k127_2204233_15 SnoaL-like domain - - - 0.0000000000000000000000000000002517 130.0
HKD1_k127_2204233_16 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000003338 137.0
HKD1_k127_2204233_17 DinB superfamily - - - 0.000000000000000000000000007276 125.0
HKD1_k127_2204233_18 Cytochrome c - - - 0.0000000000000000000001227 104.0
HKD1_k127_2204233_19 - - - - 0.0000000000000000000005612 100.0
HKD1_k127_2204233_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.65e-199 643.0
HKD1_k127_2204233_20 transport - - - 0.000007929 58.0
HKD1_k127_2204233_21 sequence-specific DNA binding - - - 0.0003837 51.0
HKD1_k127_2204233_3 CoA-binding domain K03606 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 608.0
HKD1_k127_2204233_4 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 543.0
HKD1_k127_2204233_5 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 484.0
HKD1_k127_2204233_6 Major facilitator superfamily K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 435.0
HKD1_k127_2204233_7 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 398.0
HKD1_k127_2204233_8 polygalacturonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004908 299.0
HKD1_k127_2204233_9 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000006359 260.0
HKD1_k127_2258948_0 UvrD/REP helicase N-terminal domain - - - 3.492e-252 812.0
HKD1_k127_2258948_1 LeuA allosteric (dimerisation) domain K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 608.0
HKD1_k127_2258948_2 metal-dependent hydrolase of the K07045,K14333,K15063,K20941 - 4.1.1.103,4.1.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 398.0
HKD1_k127_2258948_3 2OG-Fe dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 324.0
HKD1_k127_2258948_4 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 301.0
HKD1_k127_2258948_5 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 306.0
HKD1_k127_2258948_6 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001895 270.0
HKD1_k127_2258948_7 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000004996 160.0
HKD1_k127_2271756_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1235.0
HKD1_k127_2271756_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.734e-259 808.0
HKD1_k127_2271756_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 469.0
HKD1_k127_2271756_11 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 427.0
HKD1_k127_2271756_12 LytB protein K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 423.0
HKD1_k127_2271756_13 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 407.0
HKD1_k127_2271756_14 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 428.0
HKD1_k127_2271756_15 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 407.0
HKD1_k127_2271756_16 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 399.0
HKD1_k127_2271756_17 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 374.0
HKD1_k127_2271756_18 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008129 354.0
HKD1_k127_2271756_19 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 330.0
HKD1_k127_2271756_2 Voltage gated chloride channel - - - 4.224e-241 761.0
HKD1_k127_2271756_20 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 323.0
HKD1_k127_2271756_21 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 332.0
HKD1_k127_2271756_22 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 325.0
HKD1_k127_2271756_23 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 331.0
HKD1_k127_2271756_24 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 315.0
HKD1_k127_2271756_25 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 312.0
HKD1_k127_2271756_26 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 316.0
HKD1_k127_2271756_27 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 329.0
HKD1_k127_2271756_28 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 314.0
HKD1_k127_2271756_29 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 295.0
HKD1_k127_2271756_3 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 1.008e-211 670.0
HKD1_k127_2271756_30 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002214 283.0
HKD1_k127_2271756_31 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000442 287.0
HKD1_k127_2271756_32 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000003371 278.0
HKD1_k127_2271756_33 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004342 252.0
HKD1_k127_2271756_34 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009115 265.0
HKD1_k127_2271756_35 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000007417 235.0
HKD1_k127_2271756_36 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000001028 213.0
HKD1_k127_2271756_37 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000003492 211.0
HKD1_k127_2271756_38 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000004833 193.0
HKD1_k127_2271756_39 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000001848 190.0
HKD1_k127_2271756_4 PQQ-like domain - - - 1.341e-210 669.0
HKD1_k127_2271756_40 Thiol-disulfide oxidoreductase DCC - - - 0.00000000000000000000000000000000000000000002378 165.0
HKD1_k127_2271756_41 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000006511 175.0
HKD1_k127_2271756_42 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.0000000000000000000000000000000000000000001535 177.0
HKD1_k127_2271756_43 SNARE associated Golgi protein K19302 - 3.6.1.27 0.000000000000000000000000000000000000000008459 160.0
HKD1_k127_2271756_44 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000001249 160.0
HKD1_k127_2271756_45 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000006911 153.0
HKD1_k127_2271756_46 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000001374 145.0
HKD1_k127_2271756_47 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000006088 142.0
HKD1_k127_2271756_48 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000001145 149.0
HKD1_k127_2271756_49 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000004936 143.0
HKD1_k127_2271756_5 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 4.507e-208 670.0
HKD1_k127_2271756_50 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.0000000000000000000000000000000001328 151.0
HKD1_k127_2271756_51 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000000000004892 138.0
HKD1_k127_2271756_52 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000003001 134.0
HKD1_k127_2271756_53 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000009979 139.0
HKD1_k127_2271756_54 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000000000000000000001134 130.0
HKD1_k127_2271756_55 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000003836 134.0
HKD1_k127_2271756_56 Tetratricopeptide repeats - - - 0.00000000000000000000000000004607 135.0
HKD1_k127_2271756_57 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000001221 111.0
HKD1_k127_2271756_58 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000009329 110.0
HKD1_k127_2271756_59 phosphorelay signal transduction system - - - 0.0000000000000000000000567 113.0
HKD1_k127_2271756_6 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 538.0
HKD1_k127_2271756_60 - - - - 0.0000000000000000000008475 110.0
HKD1_k127_2271756_61 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000153 96.0
HKD1_k127_2271756_62 Helix-turn-helix domain K15539 - - 0.0000000000000000005878 99.0
HKD1_k127_2271756_63 Rieske [2Fe-2S] domain - - - 0.000000000000000001499 91.0
HKD1_k127_2271756_64 RNA polymerase-binding protein DksA K06204 - - 0.000000000000000006414 87.0
HKD1_k127_2271756_65 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000009689 89.0
HKD1_k127_2271756_67 - - - - 0.000000000007233 68.0
HKD1_k127_2271756_68 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000001249 63.0
HKD1_k127_2271756_69 Belongs to the UPF0109 family K06960 - - 0.0000000004566 69.0
HKD1_k127_2271756_7 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 520.0
HKD1_k127_2271756_70 Bacterial regulatory protein, Fis family - - - 0.000000009947 58.0
HKD1_k127_2271756_71 Heavy-metal resistance - - - 0.000003026 57.0
HKD1_k127_2271756_72 Domain of unknown function (DU1801) - - - 0.000003051 55.0
HKD1_k127_2271756_73 RHS Repeat - - - 0.000003652 59.0
HKD1_k127_2271756_74 - - - - 0.00002531 53.0
HKD1_k127_2271756_75 RDD family - - - 0.00003013 57.0
HKD1_k127_2271756_76 Belongs to the ompA family K03640 - - 0.0001722 53.0
HKD1_k127_2271756_8 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 518.0
HKD1_k127_2271756_9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 485.0
HKD1_k127_2281868_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K00480 - 1.14.13.1 1.443e-252 789.0
HKD1_k127_2281868_1 - - - - 0.000000000000000000000000000000000000000000000000002059 195.0
HKD1_k127_2281868_10 Protein of unknown function (DUF3738) - - - 0.00002997 47.0
HKD1_k127_2281868_2 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000002739 198.0
HKD1_k127_2281868_3 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000004356 203.0
HKD1_k127_2281868_4 beta-lactamase activity K07126 - - 0.000000000000000000000000000000000000000000000007296 181.0
HKD1_k127_2281868_5 - - - - 0.000000000000000000000000000000000000000000003357 176.0
HKD1_k127_2281868_6 - - - - 0.00000000000000000000000000000000000000000001201 166.0
HKD1_k127_2281868_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000007227 151.0
HKD1_k127_2281868_8 PAS fold - - - 0.0000000001492 66.0
HKD1_k127_2281868_9 Integrase core domain - - - 0.0000001749 55.0
HKD1_k127_2298037_0 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 463.0
HKD1_k127_2298037_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 386.0
HKD1_k127_2298037_2 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000156 159.0
HKD1_k127_2303464_0 AMP-binding enzyme K12508 - 6.2.1.34 1.903e-194 628.0
HKD1_k127_2303464_1 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 598.0
HKD1_k127_2303464_10 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000003631 226.0
HKD1_k127_2303464_11 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000007632 210.0
HKD1_k127_2303464_12 thiolester hydrolase activity K06889,K07000 - - 0.000000000000000000000000000000000004803 144.0
HKD1_k127_2303464_13 - - - - 0.00000000000000000000000000000000003412 147.0
HKD1_k127_2303464_14 Nuclear protein SET K07117 - - 0.0000000000000000000000327 106.0
HKD1_k127_2303464_15 Cupin - - - 0.0000000000000000000000377 106.0
HKD1_k127_2303464_16 DNA-binding transcription factor activity - - - 0.0000000000000000000123 94.0
HKD1_k127_2303464_17 Belongs to the 'phage' integrase family - - - 0.0000000000000000002057 94.0
HKD1_k127_2303464_18 Belongs to the 'phage' integrase family - - - 0.00000000000008366 75.0
HKD1_k127_2303464_19 30S ribosomal protein S23 - - - 0.00000000000241 72.0
HKD1_k127_2303464_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 598.0
HKD1_k127_2303464_20 - - - - 0.0000000005747 64.0
HKD1_k127_2303464_3 Feruloyl esterase K21105 - 3.1.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 524.0
HKD1_k127_2303464_4 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 479.0
HKD1_k127_2303464_5 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 435.0
HKD1_k127_2303464_6 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 422.0
HKD1_k127_2303464_7 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 414.0
HKD1_k127_2303464_8 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 415.0
HKD1_k127_2303464_9 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 370.0
HKD1_k127_2317419_0 DNA topological change K03168 - 5.99.1.2 4.715e-245 781.0
HKD1_k127_2317419_1 DNA topological change K03168 - 5.99.1.2 5.303e-244 784.0
HKD1_k127_2317419_10 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 318.0
HKD1_k127_2317419_11 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005813 274.0
HKD1_k127_2317419_12 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003853 269.0
HKD1_k127_2317419_13 acetylesterase activity K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000000000000000000007923 219.0
HKD1_k127_2317419_14 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000001232 215.0
HKD1_k127_2317419_15 belongs to the thioredoxin family K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000003115 181.0
HKD1_k127_2317419_16 2 iron, 2 sulfur cluster binding K13771,K13772 - - 0.000000000000000000000000000000000000000000000001742 178.0
HKD1_k127_2317419_17 - - - - 0.00000000000000000000000000000000000000003209 172.0
HKD1_k127_2317419_18 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000601 169.0
HKD1_k127_2317419_19 ankyrin repeat - - - 0.000000000000000000000000000000000000008446 162.0
HKD1_k127_2317419_2 DNA topological change - - - 2.108e-227 734.0
HKD1_k127_2317419_20 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000001252 147.0
HKD1_k127_2317419_21 Methyltransferase domain - - - 0.00000000000000000000000000000001273 136.0
HKD1_k127_2317419_22 Lipase (class 3) K01046 - 3.1.1.3 0.00000000000000000000000000005308 129.0
HKD1_k127_2317419_23 amidohydrolase - - - 0.000000000000000000000005176 117.0
HKD1_k127_2317419_24 Protein of unknown function (DUF504) - - - 0.00000000000000000000008579 102.0
HKD1_k127_2317419_25 - - - - 0.0000000000000000000002552 111.0
HKD1_k127_2317419_26 - - - - 0.00000000000000000007516 100.0
HKD1_k127_2317419_27 - - - - 0.00000000000000003079 92.0
HKD1_k127_2317419_28 Pfam:N_methyl_2 - - - 0.000000000000002946 84.0
HKD1_k127_2317419_29 Alkyl hydroperoxide reductase - - - 0.000000000001101 76.0
HKD1_k127_2317419_3 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 557.0
HKD1_k127_2317419_30 SnoaL-like domain - - - 0.000000001666 68.0
HKD1_k127_2317419_31 Photosynthetic reaction centre cytochrome C subunit - - - 0.000000005566 66.0
HKD1_k127_2317419_32 COG0457 FOG TPR repeat - - - 0.00000001121 68.0
HKD1_k127_2317419_33 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor - - - 0.00000007353 66.0
HKD1_k127_2317419_35 SnoaL-like domain - - - 0.000001431 61.0
HKD1_k127_2317419_36 SnoaL-like domain - - - 0.000002496 60.0
HKD1_k127_2317419_37 SnoaL-like domain - - - 0.000003906 59.0
HKD1_k127_2317419_39 SnoaL-like domain - - - 0.0003909 53.0
HKD1_k127_2317419_4 Multicopper oxidase K04753 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 515.0
HKD1_k127_2317419_40 SnoaL-like domain - - - 0.000454 52.0
HKD1_k127_2317419_41 SnoaL-like domain - - - 0.00049 53.0
HKD1_k127_2317419_42 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0008862 50.0
HKD1_k127_2317419_5 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 483.0
HKD1_k127_2317419_6 family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 461.0
HKD1_k127_2317419_7 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 441.0
HKD1_k127_2317419_8 long-chain fatty acid transporting porin activity K09806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 410.0
HKD1_k127_2317419_9 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 409.0
HKD1_k127_232131_0 Domain of unknown function (DUF4861) K01051 - 3.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000001595 259.0
HKD1_k127_232131_1 Glycosyl Hydrolase Family 88 - - - 0.000000000000000000000000000000000000000000000000000114 189.0
HKD1_k127_232131_2 FCD K05799 - - 0.0000000000000000000000000133 113.0
HKD1_k127_2345248_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1416.0
HKD1_k127_2345248_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 4.907e-296 933.0
HKD1_k127_2345248_10 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 447.0
HKD1_k127_2345248_11 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 437.0
HKD1_k127_2345248_12 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 423.0
HKD1_k127_2345248_13 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 426.0
HKD1_k127_2345248_14 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 412.0
HKD1_k127_2345248_15 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 399.0
HKD1_k127_2345248_16 TIGRFAM deoxyguanosinetriphosphate triphosphohydrolase K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 396.0
HKD1_k127_2345248_17 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 340.0
HKD1_k127_2345248_18 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 351.0
HKD1_k127_2345248_19 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008247 325.0
HKD1_k127_2345248_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.98e-234 761.0
HKD1_k127_2345248_20 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 323.0
HKD1_k127_2345248_21 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 314.0
HKD1_k127_2345248_22 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 309.0
HKD1_k127_2345248_23 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 294.0
HKD1_k127_2345248_24 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 295.0
HKD1_k127_2345248_25 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003353 283.0
HKD1_k127_2345248_26 Bacillithiol biosynthesis BshC K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002522 294.0
HKD1_k127_2345248_27 Belongs to the ClpA ClpB family K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003556 278.0
HKD1_k127_2345248_28 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001658 278.0
HKD1_k127_2345248_29 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001658 274.0
HKD1_k127_2345248_3 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 602.0
HKD1_k127_2345248_30 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003646 277.0
HKD1_k127_2345248_31 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000007249 267.0
HKD1_k127_2345248_32 Udp N-acetylglucosamine O-acyltransferase; Domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002449 272.0
HKD1_k127_2345248_33 Phosphoribosyl-ATP pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002042 255.0
HKD1_k127_2345248_34 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000004284 256.0
HKD1_k127_2345248_35 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000003286 254.0
HKD1_k127_2345248_36 Amidohydrolase family K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000762 257.0
HKD1_k127_2345248_37 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000004169 250.0
HKD1_k127_2345248_38 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000003006 266.0
HKD1_k127_2345248_39 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000006655 259.0
HKD1_k127_2345248_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 565.0
HKD1_k127_2345248_40 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000001099 231.0
HKD1_k127_2345248_41 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000002178 230.0
HKD1_k127_2345248_42 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000001673 217.0
HKD1_k127_2345248_43 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.0000000000000000000000000000000000000000000000000000003226 213.0
HKD1_k127_2345248_44 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000003006 183.0
HKD1_k127_2345248_45 domain protein - - - 0.0000000000000000000000000000000000000000003321 179.0
HKD1_k127_2345248_46 Putative ABC exporter - - - 0.0000000000000000000000000000000000000000004175 179.0
HKD1_k127_2345248_47 Transglycosylase SLT domain K01185 - 3.2.1.17 0.0000000000000000000000000000000000004447 149.0
HKD1_k127_2345248_48 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000005434 149.0
HKD1_k127_2345248_49 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000006256 158.0
HKD1_k127_2345248_5 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 503.0
HKD1_k127_2345248_50 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.0000000000000000000000000000000002935 145.0
HKD1_k127_2345248_51 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000000000000000008349 136.0
HKD1_k127_2345248_52 Ribosomal protein L11 methyltransferase K02687 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000002019 136.0
HKD1_k127_2345248_53 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000002939 115.0
HKD1_k127_2345248_54 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000013 115.0
HKD1_k127_2345248_55 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000003541 113.0
HKD1_k127_2345248_56 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000001545 105.0
HKD1_k127_2345248_57 Lipopolysaccharide-assembly - - - 0.000000000000000006747 99.0
HKD1_k127_2345248_58 Ribosomal L32p protein family K02911 - - 0.000000000000000008865 93.0
HKD1_k127_2345248_59 - - - - 0.0000000000000001004 94.0
HKD1_k127_2345248_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 473.0
HKD1_k127_2345248_60 serine threonine protein kinase K08884 - 2.7.11.1 0.0000000000000001327 94.0
HKD1_k127_2345248_61 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000002482 79.0
HKD1_k127_2345248_62 Domain of unknown function (DUF1844) - - - 0.000000000000006703 78.0
HKD1_k127_2345248_63 TonB C terminal - - - 0.00000000000005462 83.0
HKD1_k127_2345248_64 Modulates RecA activity K03565 - - 0.0000000002553 71.0
HKD1_k127_2345248_65 Methyltransferase FkbM domain - - - 0.000000003359 66.0
HKD1_k127_2345248_66 unfolded protein binding K06142 - - 0.00000002085 64.0
HKD1_k127_2345248_68 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000001674 59.0
HKD1_k127_2345248_7 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 464.0
HKD1_k127_2345248_8 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 458.0
HKD1_k127_2345248_9 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 471.0
HKD1_k127_2356654_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 1.692e-283 887.0
HKD1_k127_2356654_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.052e-219 693.0
HKD1_k127_2356654_10 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.00000000000000000000000000000000000000000009673 168.0
HKD1_k127_2356654_11 - - - - 0.00000000000000000000000000000007512 134.0
HKD1_k127_2356654_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000003206 130.0
HKD1_k127_2356654_13 - - - - 0.0000000000000000000000008172 109.0
HKD1_k127_2356654_14 23S rRNA-intervening sequence protein - - - 0.000000000000009071 79.0
HKD1_k127_2356654_15 - - - - 0.000007508 57.0
HKD1_k127_2356654_2 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 557.0
HKD1_k127_2356654_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 473.0
HKD1_k127_2356654_4 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 460.0
HKD1_k127_2356654_5 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 409.0
HKD1_k127_2356654_6 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 367.0
HKD1_k127_2356654_7 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009308 246.0
HKD1_k127_2356654_8 Protein of unknown function DUF126 K09128 - - 0.00000000000000000000000000000000000000000000000000000002357 199.0
HKD1_k127_2356654_9 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000001763 194.0
HKD1_k127_2377267_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.437e-271 846.0
HKD1_k127_2433434_0 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 374.0
HKD1_k127_2433434_1 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002506 262.0
HKD1_k127_2433434_2 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000005872 234.0
HKD1_k127_2433434_3 COG3893 Inactivated superfamily I helicase K16899 - 3.6.4.12 0.00000000002934 78.0
HKD1_k127_2449177_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 385.0
HKD1_k127_2449177_1 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000003543 194.0
HKD1_k127_2449177_2 SnoaL-like polyketide cyclase - - - 0.00000000000006529 79.0
HKD1_k127_2465190_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 481.0
HKD1_k127_2465190_1 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 484.0
HKD1_k127_2465190_2 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 428.0
HKD1_k127_2465190_3 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001769 310.0
HKD1_k127_2465190_4 Pfam:N_methyl_2 - - - 0.000000696 55.0
HKD1_k127_2487377_0 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 543.0
HKD1_k127_2487377_1 MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 404.0
HKD1_k127_2487377_2 Serine aminopeptidase, S33 K19311 GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016298,GO:0016787,GO:0016788,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0072329,GO:0104004,GO:1901575 - 0.0000000000000000000000000000000000000006404 160.0
HKD1_k127_2487377_3 PFAM S23 ribosomal protein - - - 0.000000000000009413 79.0
HKD1_k127_2488910_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 541.0
HKD1_k127_2488910_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 522.0
HKD1_k127_2488910_2 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 470.0
HKD1_k127_2489647_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1204.0
HKD1_k127_2489647_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.984e-285 889.0
HKD1_k127_2489647_10 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 488.0
HKD1_k127_2489647_11 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 467.0
HKD1_k127_2489647_12 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 454.0
HKD1_k127_2489647_13 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 446.0
HKD1_k127_2489647_14 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007235 429.0
HKD1_k127_2489647_15 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 414.0
HKD1_k127_2489647_16 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 422.0
HKD1_k127_2489647_17 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 399.0
HKD1_k127_2489647_18 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 402.0
HKD1_k127_2489647_19 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 378.0
HKD1_k127_2489647_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 1.282e-254 810.0
HKD1_k127_2489647_20 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 373.0
HKD1_k127_2489647_21 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 357.0
HKD1_k127_2489647_22 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 351.0
HKD1_k127_2489647_23 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 331.0
HKD1_k127_2489647_24 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 349.0
HKD1_k127_2489647_25 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 316.0
HKD1_k127_2489647_26 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005716 277.0
HKD1_k127_2489647_27 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001034 289.0
HKD1_k127_2489647_28 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000004696 265.0
HKD1_k127_2489647_29 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008568 272.0
HKD1_k127_2489647_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 7.112e-220 695.0
HKD1_k127_2489647_30 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000001308 241.0
HKD1_k127_2489647_31 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000000000000000002332 233.0
HKD1_k127_2489647_32 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000001957 236.0
HKD1_k127_2489647_33 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000001332 228.0
HKD1_k127_2489647_34 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000001938 238.0
HKD1_k127_2489647_35 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000003515 221.0
HKD1_k127_2489647_36 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000003002 220.0
HKD1_k127_2489647_37 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000002596 229.0
HKD1_k127_2489647_38 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000002592 197.0
HKD1_k127_2489647_39 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000001191 194.0
HKD1_k127_2489647_4 Glycosyl transferase family 21 - - - 1.125e-194 618.0
HKD1_k127_2489647_40 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000001952 187.0
HKD1_k127_2489647_41 Dna alkylation repair - - - 0.00000000000000000000000000000000000004472 155.0
HKD1_k127_2489647_42 Organic solvent tolerance protein K04744 - - 0.0000000000000000000000000000000000001995 164.0
HKD1_k127_2489647_43 Reverse transcriptase-like K03469 - 3.1.26.4 0.00000000000000000000000000000000009814 141.0
HKD1_k127_2489647_44 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000001197 134.0
HKD1_k127_2489647_45 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000128 132.0
HKD1_k127_2489647_46 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000002684 129.0
HKD1_k127_2489647_47 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000003027 124.0
HKD1_k127_2489647_48 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000609 106.0
HKD1_k127_2489647_5 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 627.0
HKD1_k127_2489647_50 DivIVA protein K04074 - - 0.000000000000000000002105 101.0
HKD1_k127_2489647_51 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000368 93.0
HKD1_k127_2489647_52 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000005052 86.0
HKD1_k127_2489647_53 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000003413 86.0
HKD1_k127_2489647_54 PFAM Tetratricopeptide repeat - - - 0.00000000000005306 83.0
HKD1_k127_2489647_55 Cell division protein FtsQ K03589 - - 0.00000003165 66.0
HKD1_k127_2489647_6 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 566.0
HKD1_k127_2489647_7 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 567.0
HKD1_k127_2489647_8 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 546.0
HKD1_k127_2489647_9 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 499.0
HKD1_k127_250194_0 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 4.662e-237 744.0
HKD1_k127_2547914_0 1,4-alpha-glucan branching enzyme activity K00700,K01236 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.141 4.469e-295 933.0
HKD1_k127_2547914_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 454.0
HKD1_k127_2547914_10 Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1 - - - 0.000000000000000000000000000000000000000000000000000001569 214.0
HKD1_k127_2547914_11 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000002953 203.0
HKD1_k127_2547914_12 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000001852 205.0
HKD1_k127_2547914_13 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000000000001854 173.0
HKD1_k127_2547914_14 G/U mismatch-specific uracil-DNA glycosylase activity K01934,K03649 GO:0000700,GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008263,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.28,6.3.3.2 0.00000000000000000000000000000000000000000002138 168.0
HKD1_k127_2547914_15 EVE domain - - - 0.0000000000000000000000000000000000000000005233 163.0
HKD1_k127_2547914_16 - - - - 0.000000000000000000000000000000000011 149.0
HKD1_k127_2547914_17 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000001148 143.0
HKD1_k127_2547914_18 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000001358 133.0
HKD1_k127_2547914_19 L-lactate permease K03303 - - 0.0000000000000000000000000001866 116.0
HKD1_k127_2547914_2 Belongs to the peptidase M48B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 427.0
HKD1_k127_2547914_20 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000006292 129.0
HKD1_k127_2547914_21 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000000007623 108.0
HKD1_k127_2547914_22 - - - - 0.00000000000000009796 95.0
HKD1_k127_2547914_23 Methionine biosynthesis protein MetW - - - 0.00000000008764 71.0
HKD1_k127_2547914_3 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 392.0
HKD1_k127_2547914_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 322.0
HKD1_k127_2547914_5 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 331.0
HKD1_k127_2547914_6 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000003083 236.0
HKD1_k127_2547914_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000002811 231.0
HKD1_k127_2547914_8 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000001623 222.0
HKD1_k127_2547914_9 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000000001284 212.0
HKD1_k127_2562783_0 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006488 253.0
HKD1_k127_2562783_1 T4-like virus tail tube protein gp19 - - - 0.00000000000000000004352 98.0
HKD1_k127_2562783_2 ATPase involved in DNA repair - - - 0.000000285 60.0
HKD1_k127_256410_0 DEAD DEAH box K03724 - - 0.0 1877.0
HKD1_k127_256410_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K22015 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0015942,GO:0015944,GO:0016491,GO:0016651,GO:0016999,GO:0017144,GO:0019752,GO:0030151,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704 1.17.1.9,1.17.99.7 0.0 1428.0
HKD1_k127_256410_10 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 2.43e-202 649.0
HKD1_k127_256410_100 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000002549 147.0
HKD1_k127_256410_101 Cytochrome c - - - 0.00000000000000000000000000000003878 130.0
HKD1_k127_256410_102 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000003109 138.0
HKD1_k127_256410_103 phospholipase Carboxylesterase - - - 0.000000000000000000000000000004013 131.0
HKD1_k127_256410_104 Belongs to the ompA family - - - 0.000000000000000000000000000009384 128.0
HKD1_k127_256410_105 SnoaL-like domain - - - 0.00000000000000000000000000001019 130.0
HKD1_k127_256410_106 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000001171 119.0
HKD1_k127_256410_107 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000001872 123.0
HKD1_k127_256410_108 transport - - - 0.0000000000000000000000000001758 134.0
HKD1_k127_256410_109 - - - - 0.0000000000000000000000000003731 124.0
HKD1_k127_256410_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 9.507e-202 636.0
HKD1_k127_256410_110 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000004836 117.0
HKD1_k127_256410_111 Putative zinc-finger - - - 0.000000000000000000000000001779 123.0
HKD1_k127_256410_112 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000001908 118.0
HKD1_k127_256410_113 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000001916 112.0
HKD1_k127_256410_115 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000009418 129.0
HKD1_k127_256410_116 SnoaL-like domain - - - 0.0000000000000000000000001271 118.0
HKD1_k127_256410_117 Trehalose-phosphatase K16055 - 2.4.1.15,3.1.3.12 0.0000000000000000000000001588 121.0
HKD1_k127_256410_118 - - - - 0.000000000000000000000000244 123.0
HKD1_k127_256410_119 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000493 111.0
HKD1_k127_256410_12 Phosphofructokinase - - - 4.099e-196 621.0
HKD1_k127_256410_120 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000121 119.0
HKD1_k127_256410_121 NIPSNAP - - - 0.000000000000000000000003192 117.0
HKD1_k127_256410_122 - - - - 0.0000000000000000000008741 106.0
HKD1_k127_256410_123 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000172 106.0
HKD1_k127_256410_124 - - - - 0.000000000000000000006749 109.0
HKD1_k127_256410_125 - - - - 0.000000000000000001183 97.0
HKD1_k127_256410_126 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000003167 90.0
HKD1_k127_256410_127 - - - - 0.00000000000000000856 91.0
HKD1_k127_256410_128 SnoaL-like domain - - - 0.00000000000000001153 88.0
HKD1_k127_256410_129 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000001377 83.0
HKD1_k127_256410_13 Tetratricopeptide TPR_2 repeat protein - - - 2.633e-194 634.0
HKD1_k127_256410_130 Trm112p-like protein K00912,K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 0.0000000000000001835 80.0
HKD1_k127_256410_131 - - - - 0.0000000000000008477 91.0
HKD1_k127_256410_132 Stress-induced bacterial acidophilic repeat motif K06884 - - 0.000000000000002484 78.0
HKD1_k127_256410_133 - - - - 0.000000000000003354 90.0
HKD1_k127_256410_134 Domain of unknown function (DUF4440) - - - 0.00000000000001291 80.0
HKD1_k127_256410_135 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.0000000000001787 85.0
HKD1_k127_256410_136 - - - - 0.0000000000008483 74.0
HKD1_k127_256410_137 23S rRNA-intervening sequence protein - - - 0.0000000000008787 72.0
HKD1_k127_256410_138 PFAM PspC domain K03973 - - 0.00000000001921 76.0
HKD1_k127_256410_139 Helix-turn-helix domain K15539 - - 0.0000000001438 72.0
HKD1_k127_256410_14 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 585.0
HKD1_k127_256410_140 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000008633 68.0
HKD1_k127_256410_141 domain, Protein - - - 0.000000002317 66.0
HKD1_k127_256410_142 Outer membrane lipoprotein-sorting protein - - - 0.000000002554 60.0
HKD1_k127_256410_143 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000006998 61.0
HKD1_k127_256410_145 integral membrane protein K00728 - 2.4.1.109 0.0000001387 64.0
HKD1_k127_256410_146 - - - - 0.000003446 58.0
HKD1_k127_256410_148 - - - - 0.00007774 45.0
HKD1_k127_256410_149 - - - - 0.0001463 56.0
HKD1_k127_256410_15 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 578.0
HKD1_k127_256410_150 Transcriptional regulator - - - 0.0009008 48.0
HKD1_k127_256410_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 518.0
HKD1_k127_256410_17 phosphorelay signal transduction system K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 516.0
HKD1_k127_256410_18 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 504.0
HKD1_k127_256410_19 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 497.0
HKD1_k127_256410_2 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 6.208e-319 1002.0
HKD1_k127_256410_20 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 494.0
HKD1_k127_256410_21 Surface antigen K07277,K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 533.0
HKD1_k127_256410_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 454.0
HKD1_k127_256410_23 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.17,6.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 463.0
HKD1_k127_256410_24 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 454.0
HKD1_k127_256410_25 PFAM glycosyl transferase family 51 K05366,K21464 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 452.0
HKD1_k127_256410_26 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 397.0
HKD1_k127_256410_27 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 405.0
HKD1_k127_256410_28 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 385.0
HKD1_k127_256410_29 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 385.0
HKD1_k127_256410_30 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 380.0
HKD1_k127_256410_31 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 403.0
HKD1_k127_256410_32 TIR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 370.0
HKD1_k127_256410_33 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 389.0
HKD1_k127_256410_34 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 357.0
HKD1_k127_256410_35 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 338.0
HKD1_k127_256410_37 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 347.0
HKD1_k127_256410_38 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 311.0
HKD1_k127_256410_39 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 315.0
HKD1_k127_256410_4 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 1.371e-249 795.0
HKD1_k127_256410_40 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 315.0
HKD1_k127_256410_41 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 303.0
HKD1_k127_256410_42 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 296.0
HKD1_k127_256410_43 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 313.0
HKD1_k127_256410_44 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 305.0
HKD1_k127_256410_45 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 298.0
HKD1_k127_256410_46 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 302.0
HKD1_k127_256410_47 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 296.0
HKD1_k127_256410_48 mandelate racemase muconate lactonizing K01684,K01781,K08323 - 4.2.1.6,4.2.1.8,5.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 300.0
HKD1_k127_256410_49 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 310.0
HKD1_k127_256410_5 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00124 - - 4.243e-247 779.0
HKD1_k127_256410_50 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007157 284.0
HKD1_k127_256410_51 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003552 297.0
HKD1_k127_256410_52 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005274 275.0
HKD1_k127_256410_53 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004248 259.0
HKD1_k127_256410_54 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001111 252.0
HKD1_k127_256410_55 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003464 251.0
HKD1_k127_256410_56 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007872 247.0
HKD1_k127_256410_57 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008219 230.0
HKD1_k127_256410_58 Belongs to the FPG family K05522 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000001536 231.0
HKD1_k127_256410_59 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000007331 241.0
HKD1_k127_256410_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 1.989e-238 749.0
HKD1_k127_256410_60 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.00000000000000000000000000000000000000000000000000000000000001083 218.0
HKD1_k127_256410_61 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000003448 238.0
HKD1_k127_256410_62 - - - - 0.0000000000000000000000000000000000000000000000000000000000007873 216.0
HKD1_k127_256410_63 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000004642 201.0
HKD1_k127_256410_64 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000005502 211.0
HKD1_k127_256410_65 - - - - 0.00000000000000000000000000000000000000000000000000000007031 218.0
HKD1_k127_256410_66 phosphinothricin N-acetyltransferase activity K03825 - - 0.00000000000000000000000000000000000000000000000000000009127 203.0
HKD1_k127_256410_67 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000144 198.0
HKD1_k127_256410_68 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000000000000000000000000000001704 211.0
HKD1_k127_256410_69 Glycosyl transferase, family 9 K02843,K02849 - - 0.0000000000000000000000000000000000000000000000000001253 200.0
HKD1_k127_256410_7 Major Facilitator Superfamily - - - 1.063e-217 686.0
HKD1_k127_256410_70 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000001262 195.0
HKD1_k127_256410_71 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000001817 196.0
HKD1_k127_256410_72 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000000000000000000000000000002144 191.0
HKD1_k127_256410_73 PFAM Molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000007225 196.0
HKD1_k127_256410_74 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000004759 189.0
HKD1_k127_256410_75 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000008126 182.0
HKD1_k127_256410_76 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000156 184.0
HKD1_k127_256410_77 O-Antigen ligase K18814 - - 0.000000000000000000000000000000000000000000000001123 198.0
HKD1_k127_256410_78 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000002712 186.0
HKD1_k127_256410_79 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K13524 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000001046 192.0
HKD1_k127_256410_8 DNA topological change K03168 - 5.99.1.2 3.01e-217 702.0
HKD1_k127_256410_80 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000004205 182.0
HKD1_k127_256410_81 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000001992 180.0
HKD1_k127_256410_82 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000002208 171.0
HKD1_k127_256410_84 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000005292 178.0
HKD1_k127_256410_85 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000001991 169.0
HKD1_k127_256410_86 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000001667 173.0
HKD1_k127_256410_87 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000002379 155.0
HKD1_k127_256410_88 NADH dehydrogenase (ubiquinone) flavoprotein 2 K03943 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0007275,GO:0007399,GO:0007507,GO:0008137,GO:0008150,GO:0008152,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009888,GO:0009987,GO:0010257,GO:0014706,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042773,GO:0042775,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0048513,GO:0048731,GO:0048738,GO:0048856,GO:0050136,GO:0055086,GO:0055114,GO:0060537,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072359,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000003078 160.0
HKD1_k127_256410_89 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000003384 176.0
HKD1_k127_256410_9 DNA topological change K03168 - 5.99.1.2 1.159e-210 684.0
HKD1_k127_256410_90 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000105 154.0
HKD1_k127_256410_91 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000002632 152.0
HKD1_k127_256410_92 TIR domain - - - 0.000000000000000000000000000000000000004646 163.0
HKD1_k127_256410_93 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000007005 148.0
HKD1_k127_256410_94 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000000001437 145.0
HKD1_k127_256410_95 PFAM DinB family protein - - - 0.0000000000000000000000000000000001939 138.0
HKD1_k127_256410_96 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000005707 149.0
HKD1_k127_256410_97 YCII-related domain K09780 - - 0.000000000000000000000000000000000647 136.0
HKD1_k127_256410_98 GrpB protein - - - 0.0000000000000000000000000000000008735 145.0
HKD1_k127_256410_99 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.000000000000000000000000000000002488 139.0
HKD1_k127_2572746_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1080.0
HKD1_k127_2572746_1 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000001449 156.0
HKD1_k127_2572746_2 Universal stress protein - - - 0.00000001803 64.0
HKD1_k127_265211_0 Monooxygenase, FAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 451.0
HKD1_k127_265211_1 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000333 248.0
HKD1_k127_265211_3 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000003657 128.0
HKD1_k127_2699047_0 Nadh flavin oxidoreductase nadh oxidase K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 401.0
HKD1_k127_2699047_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000009694 225.0
HKD1_k127_2699047_2 - - - - 0.00000000000000000000005177 102.0
HKD1_k127_2699047_3 - - - - 0.000000000000007534 83.0
HKD1_k127_2699047_4 Helix-turn-helix XRE-family like proteins - - - 0.0000000000002144 78.0
HKD1_k127_2699047_5 Beta-lactamase - - - 0.00001324 50.0
HKD1_k127_2868130_0 Belongs to the TPP enzyme family K01577 - 4.1.1.8 7.564e-321 989.0
HKD1_k127_2868130_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 306.0
HKD1_k127_2868130_2 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 0.0000000000000000004629 86.0
HKD1_k127_2911158_0 amino acid K03294 - - 7.693e-228 715.0
HKD1_k127_2911158_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 604.0
HKD1_k127_2911158_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 320.0
HKD1_k127_2911158_3 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002324 283.0
HKD1_k127_2911158_4 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001068 275.0
HKD1_k127_2911158_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000002001 153.0
HKD1_k127_2911158_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000006297 143.0
HKD1_k127_2911158_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000278 136.0
HKD1_k127_2911158_8 Tetratricopeptide repeats - - - 0.000001036 57.0
HKD1_k127_2911158_9 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00004313 48.0
HKD1_k127_2913849_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1138.0
HKD1_k127_2913849_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.966e-206 675.0
HKD1_k127_2913849_10 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 329.0
HKD1_k127_2913849_11 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 327.0
HKD1_k127_2913849_12 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 301.0
HKD1_k127_2913849_13 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 297.0
HKD1_k127_2913849_14 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004043 286.0
HKD1_k127_2913849_15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006478 277.0
HKD1_k127_2913849_16 P-loop ATPase protein family K06958 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003764 278.0
HKD1_k127_2913849_17 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000008065 263.0
HKD1_k127_2913849_18 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000001355 216.0
HKD1_k127_2913849_19 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000003509 196.0
HKD1_k127_2913849_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 554.0
HKD1_k127_2913849_20 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000001636 190.0
HKD1_k127_2913849_21 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000001876 196.0
HKD1_k127_2913849_22 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000333 166.0
HKD1_k127_2913849_23 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000004303 141.0
HKD1_k127_2913849_24 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.0000000000000000000000000000000002656 137.0
HKD1_k127_2913849_25 PHP domain protein - - - 0.000000000000000000000000000000003204 147.0
HKD1_k127_2913849_26 Histidine kinase K13598 - 2.7.13.3 0.0000000000000000000000000000004644 144.0
HKD1_k127_2913849_27 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000004433 136.0
HKD1_k127_2913849_28 Phosphotransferase System K11189 - - 0.0000000000000000000002785 105.0
HKD1_k127_2913849_29 PQQ enzyme repeat - - - 0.00000000000000000006264 106.0
HKD1_k127_2913849_3 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 553.0
HKD1_k127_2913849_30 Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000009149 96.0
HKD1_k127_2913849_31 Outer membrane lipoprotein - - - 0.00000000000001796 84.0
HKD1_k127_2913849_32 general secretion pathway protein K02456,K02650 - - 0.000000000005926 78.0
HKD1_k127_2913849_33 TonB C terminal K03646,K03832 - - 0.00000003149 64.0
HKD1_k127_2913849_34 domain protein - - - 0.0000008885 59.0
HKD1_k127_2913849_35 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.0009561 52.0
HKD1_k127_2913849_4 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 445.0
HKD1_k127_2913849_5 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 444.0
HKD1_k127_2913849_6 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 411.0
HKD1_k127_2913849_7 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 395.0
HKD1_k127_2913849_8 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 376.0
HKD1_k127_2913849_9 Permease, YjgP YjgQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 387.0
HKD1_k127_2979005_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 505.0
HKD1_k127_2979005_1 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 484.0
HKD1_k127_2979005_10 - - - - 0.00002093 53.0
HKD1_k127_2979005_2 cobalt chelatase K09883 - 6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 376.0
HKD1_k127_2979005_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 317.0
HKD1_k127_2979005_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 310.0
HKD1_k127_2979005_5 - - - - 0.00000000000000000000000000000000000000000000000000000229 212.0
HKD1_k127_2979005_6 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000006571 74.0
HKD1_k127_2979005_7 Carboxypeptidase regulatory-like domain - - - 0.00000000229 65.0
HKD1_k127_2979005_9 Protein of unknown function (DUF3443) - - - 0.00000004942 59.0
HKD1_k127_3068938_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.751e-296 921.0
HKD1_k127_3068938_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 9.845e-277 872.0
HKD1_k127_3068938_10 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 457.0
HKD1_k127_3068938_11 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 449.0
HKD1_k127_3068938_12 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 404.0
HKD1_k127_3068938_13 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 419.0
HKD1_k127_3068938_14 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 396.0
HKD1_k127_3068938_15 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 365.0
HKD1_k127_3068938_16 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 353.0
HKD1_k127_3068938_17 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 349.0
HKD1_k127_3068938_18 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 362.0
HKD1_k127_3068938_19 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 325.0
HKD1_k127_3068938_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.897e-211 667.0
HKD1_k127_3068938_20 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 337.0
HKD1_k127_3068938_21 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 314.0
HKD1_k127_3068938_22 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 308.0
HKD1_k127_3068938_23 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002083 293.0
HKD1_k127_3068938_24 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003617 274.0
HKD1_k127_3068938_25 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000549 246.0
HKD1_k127_3068938_26 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000009791 161.0
HKD1_k127_3068938_27 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000000005164 150.0
HKD1_k127_3068938_28 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000001199 133.0
HKD1_k127_3068938_29 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000001021 101.0
HKD1_k127_3068938_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 604.0
HKD1_k127_3068938_30 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000005824 94.0
HKD1_k127_3068938_31 SdpI/YhfL protein family - - - 0.00000000000002237 76.0
HKD1_k127_3068938_33 Peptidase M56 - - - 0.000004452 58.0
HKD1_k127_3068938_35 TonB dependent receptor - - - 0.0006089 53.0
HKD1_k127_3068938_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 574.0
HKD1_k127_3068938_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 516.0
HKD1_k127_3068938_6 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 507.0
HKD1_k127_3068938_7 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 493.0
HKD1_k127_3068938_8 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 481.0
HKD1_k127_3068938_9 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 464.0
HKD1_k127_3093110_0 DNA topological change K03168 - 5.99.1.2 6.77e-247 790.0
HKD1_k127_3093110_1 DNA topological change K03168 - 5.99.1.2 1.574e-238 762.0
HKD1_k127_3093110_10 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 492.0
HKD1_k127_3093110_11 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 486.0
HKD1_k127_3093110_12 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 494.0
HKD1_k127_3093110_13 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 465.0
HKD1_k127_3093110_14 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 439.0
HKD1_k127_3093110_15 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 423.0
HKD1_k127_3093110_16 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 428.0
HKD1_k127_3093110_17 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 414.0
HKD1_k127_3093110_18 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 396.0
HKD1_k127_3093110_19 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 397.0
HKD1_k127_3093110_2 Tetratricopeptide repeat - - - 3.71e-210 672.0
HKD1_k127_3093110_20 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 398.0
HKD1_k127_3093110_21 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 367.0
HKD1_k127_3093110_22 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 395.0
HKD1_k127_3093110_23 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 359.0
HKD1_k127_3093110_24 PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 359.0
HKD1_k127_3093110_25 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 340.0
HKD1_k127_3093110_26 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 319.0
HKD1_k127_3093110_27 KR domain K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 289.0
HKD1_k127_3093110_28 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001189 311.0
HKD1_k127_3093110_29 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001477 307.0
HKD1_k127_3093110_3 PQQ-like domain - - - 3.093e-201 652.0
HKD1_k127_3093110_30 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001211 276.0
HKD1_k127_3093110_31 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001199 277.0
HKD1_k127_3093110_32 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004596 260.0
HKD1_k127_3093110_33 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K08369 - - 0.000000000000000000000000000000000000000000000000000000000000000000001398 261.0
HKD1_k127_3093110_34 response to abiotic stimulus K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000000003274 251.0
HKD1_k127_3093110_35 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001082 220.0
HKD1_k127_3093110_36 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000006312 214.0
HKD1_k127_3093110_37 lactoylglutathione lyase activity K03088 - - 0.0000000000000000000000000000000000000000000000000000000000002915 234.0
HKD1_k127_3093110_38 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001191 216.0
HKD1_k127_3093110_39 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000001207 225.0
HKD1_k127_3093110_4 Protein kinase domain K12132 - 2.7.11.1 4.628e-197 649.0
HKD1_k127_3093110_40 - - - - 0.0000000000000000000000000000000000000000000000000000001279 217.0
HKD1_k127_3093110_41 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - 0.0000000000000000000000000000000000000000000000000000008179 201.0
HKD1_k127_3093110_42 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000002267 220.0
HKD1_k127_3093110_43 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000001606 187.0
HKD1_k127_3093110_44 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000001138 179.0
HKD1_k127_3093110_45 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000000008549 190.0
HKD1_k127_3093110_46 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000002485 173.0
HKD1_k127_3093110_47 - - - - 0.0000000000000000000000000000000000000000001209 172.0
HKD1_k127_3093110_48 PFAM Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000097 165.0
HKD1_k127_3093110_49 - - - - 0.0000000000000000000000000000000000000001497 163.0
HKD1_k127_3093110_5 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 612.0
HKD1_k127_3093110_50 - - - - 0.000000000000000000000000000000000000001327 163.0
HKD1_k127_3093110_51 PFAM PEBP family protein K06910 - - 0.000000000000000000000000000000000001052 145.0
HKD1_k127_3093110_52 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000002147 144.0
HKD1_k127_3093110_53 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000001572 151.0
HKD1_k127_3093110_54 domain protein - - - 0.0000000000000000000000000001062 127.0
HKD1_k127_3093110_55 peptidyl-tyrosine sulfation K13992 - - 0.00000000000000000000000003383 126.0
HKD1_k127_3093110_56 - - - - 0.0000000000000000000000001225 113.0
HKD1_k127_3093110_57 - - - - 0.000000000000000000000001068 115.0
HKD1_k127_3093110_58 Aldo keto reductase - - - 0.000000000000000000000001768 103.0
HKD1_k127_3093110_59 Protein of unknown function (DUF4019) - - - 0.00000000000000000000007424 100.0
HKD1_k127_3093110_6 MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 584.0
HKD1_k127_3093110_60 protocatechuate 3,4-dioxygenase activity - - - 0.00000000000000000005809 106.0
HKD1_k127_3093110_61 - - - - 0.0000000000000000001413 98.0
HKD1_k127_3093110_62 SnoaL-like domain - - - 0.000000000000004549 83.0
HKD1_k127_3093110_64 Sterol carrier protein - - - 0.00000000000349 71.0
HKD1_k127_3093110_65 SET domain K07117 - - 0.000000009632 63.0
HKD1_k127_3093110_66 - - - - 0.00000003638 67.0
HKD1_k127_3093110_67 - - - - 0.000002547 58.0
HKD1_k127_3093110_68 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000003187 59.0
HKD1_k127_3093110_69 DinB family - - - 0.000003844 56.0
HKD1_k127_3093110_7 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 584.0
HKD1_k127_3093110_70 Glyoxalase-like domain - - - 0.000007339 59.0
HKD1_k127_3093110_71 - - - - 0.00004633 57.0
HKD1_k127_3093110_72 COG2335, Secreted and surface protein containing fasciclin-like repeats - - - 0.0001077 50.0
HKD1_k127_3093110_8 Iron-containing alcohol dehydrogenase K11173 - 1.1.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 544.0
HKD1_k127_3093110_9 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 533.0
HKD1_k127_3103803_0 FAD linked oxidases, C-terminal domain - - - 0.0 1155.0
HKD1_k127_3103803_1 Insulinase (Peptidase family M16) K07263 - - 0.0 1125.0
HKD1_k127_3103803_10 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 515.0
HKD1_k127_3103803_11 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 540.0
HKD1_k127_3103803_12 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 476.0
HKD1_k127_3103803_13 PFAM Transketolase central region K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 467.0
HKD1_k127_3103803_14 GMC oxidoreductase K06151 - 1.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 490.0
HKD1_k127_3103803_15 Short chain fatty acid transporter K02106 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 494.0
HKD1_k127_3103803_16 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 459.0
HKD1_k127_3103803_17 Periplasmic binding proteins and sugar binding domain of LacI family K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 418.0
HKD1_k127_3103803_18 Belongs to the binding-protein-dependent transport system permease family K10440,K10553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 408.0
HKD1_k127_3103803_19 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 398.0
HKD1_k127_3103803_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1077.0
HKD1_k127_3103803_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 394.0
HKD1_k127_3103803_21 Alanine-glyoxylate amino-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 349.0
HKD1_k127_3103803_22 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 336.0
HKD1_k127_3103803_23 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 334.0
HKD1_k127_3103803_24 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 336.0
HKD1_k127_3103803_25 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 318.0
HKD1_k127_3103803_26 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 301.0
HKD1_k127_3103803_27 Bacterial protein of unknown function (DUF839) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 314.0
HKD1_k127_3103803_28 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit K21416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 291.0
HKD1_k127_3103803_29 Belongs to the HpcH HpaI aldolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008983 286.0
HKD1_k127_3103803_3 COG3119 Arylsulfatase A and related enzymes - - - 5.234e-249 784.0
HKD1_k127_3103803_30 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000009022 257.0
HKD1_k127_3103803_31 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000003976 227.0
HKD1_k127_3103803_32 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000001762 219.0
HKD1_k127_3103803_33 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000004528 224.0
HKD1_k127_3103803_34 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000002518 230.0
HKD1_k127_3103803_35 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000002542 184.0
HKD1_k127_3103803_36 - - - - 0.0000000000000000000000000000000000000000002664 176.0
HKD1_k127_3103803_37 alkylbase DNA N-glycosylase activity K03652 - 3.2.2.21 0.00000000000000000000000000000000000000004881 173.0
HKD1_k127_3103803_38 Transcriptional regulator K22293 - - 0.0000000000000000000000000000000000000001827 158.0
HKD1_k127_3103803_39 - - - - 0.00000000000000000000000000000000000001692 159.0
HKD1_k127_3103803_4 Dehydrogenase K00114 - 1.1.2.8 2.316e-232 747.0
HKD1_k127_3103803_40 MOSC domain - - - 0.000000000000000000000000000000000001189 143.0
HKD1_k127_3103803_41 Protein of unknown function (DUF3175) - - - 0.00000000000000000000000000000002996 127.0
HKD1_k127_3103803_42 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000006498 127.0
HKD1_k127_3103803_43 - - - - 0.000000000000000000000000007213 114.0
HKD1_k127_3103803_44 - - - - 0.00000000000000000000000004758 121.0
HKD1_k127_3103803_45 - - - - 0.00000000000000000000000005179 117.0
HKD1_k127_3103803_46 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549,K22363 - 2.1.1.14,4.4.1.23 0.000000000000000000001735 98.0
HKD1_k127_3103803_47 AraC-like ligand binding domain - - - 0.000000000000000000003384 111.0
HKD1_k127_3103803_48 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000001379 108.0
HKD1_k127_3103803_49 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.000000000000000001569 99.0
HKD1_k127_3103803_5 PFAM Peptidase M1, membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 8.255e-230 741.0
HKD1_k127_3103803_50 regulatory protein, FmdB family - - - 0.000000009354 59.0
HKD1_k127_3103803_52 - - - - 0.0000002544 57.0
HKD1_k127_3103803_53 - - - - 0.000007753 57.0
HKD1_k127_3103803_55 - - - - 0.0003964 53.0
HKD1_k127_3103803_56 - - - - 0.0005556 51.0
HKD1_k127_3103803_6 secondary active sulfate transmembrane transporter activity K06901 - - 1.295e-220 695.0
HKD1_k127_3103803_7 proline dipeptidase activity - - - 1.997e-203 641.0
HKD1_k127_3103803_8 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 4.73e-197 625.0
HKD1_k127_3103803_9 Oligopeptidase F K08602 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 614.0
HKD1_k127_3112559_0 PFAM LmbE family protein K22136 - - 5.651e-253 829.0
HKD1_k127_3112559_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 526.0
HKD1_k127_3112559_2 PFAM Glycosyl transferase, group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 431.0
HKD1_k127_3112559_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 365.0
HKD1_k127_3112559_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000004391 201.0
HKD1_k127_3112559_5 deacetylase K01463 - - 0.00000000000000000000000000000000000000000000000001114 205.0
HKD1_k127_3112559_6 Major facilitator superfamily K13021 - - 0.0000000000000000000000000000000000000000000000001013 185.0
HKD1_k127_3112559_7 Amino acid oxidase - - - 0.00000000000000000000000000000000003823 149.0
HKD1_k127_3112559_8 domain protein K01992 - - 0.0000000002361 63.0
HKD1_k127_3114623_0 PFAM ABC transporter transmembrane K06147 - - 1.262e-270 845.0
HKD1_k127_3114623_1 MacB-like periplasmic core domain - - - 1.618e-204 686.0
HKD1_k127_3114623_10 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 349.0
HKD1_k127_3114623_11 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 339.0
HKD1_k127_3114623_12 MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003371 275.0
HKD1_k127_3114623_13 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000003599 183.0
HKD1_k127_3114623_14 Disulphide isomerase - - - 0.000000000000000000000000000000000000000000000009363 175.0
HKD1_k127_3114623_15 Protein of unknown function (DUF2844) - - - 0.00000000000000000000000001039 116.0
HKD1_k127_3114623_16 Cysteine-rich CPXCG - - - 0.0000000001375 63.0
HKD1_k127_3114623_18 PFAM regulatory protein, MarR - - - 0.00000002455 65.0
HKD1_k127_3114623_19 PEGA domain - - - 0.000127 54.0
HKD1_k127_3114623_2 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 501.0
HKD1_k127_3114623_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 506.0
HKD1_k127_3114623_4 acyl-CoA dehydrogenase activity K00248,K00253 - 1.3.8.1,1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 457.0
HKD1_k127_3114623_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 449.0
HKD1_k127_3114623_6 G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 374.0
HKD1_k127_3114623_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 356.0
HKD1_k127_3114623_8 Protein of unknown function (DUF3443) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 358.0
HKD1_k127_3114623_9 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 346.0
HKD1_k127_3150459_0 TIGRFAM amino acid adenylation domain - - - 0.0 1601.0
HKD1_k127_3150459_1 non-ribosomal peptide synthetase - - - 0.0 1593.0
HKD1_k127_3150459_10 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002748 258.0
HKD1_k127_3150459_11 Lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001868 251.0
HKD1_k127_3150459_12 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000001496 229.0
HKD1_k127_3150459_13 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000002896 210.0
HKD1_k127_3150459_14 Circularly permuted ATP-grasp type 2 - - - 0.0000000000000000000000000000000000000000000000007976 175.0
HKD1_k127_3150459_16 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000008083 170.0
HKD1_k127_3150459_2 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 0.0 1397.0
HKD1_k127_3150459_3 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 599.0
HKD1_k127_3150459_4 COG4993 Glucose dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 385.0
HKD1_k127_3150459_5 acr, cog1565 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 355.0
HKD1_k127_3150459_6 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 341.0
HKD1_k127_3150459_7 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 339.0
HKD1_k127_3150459_8 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 332.0
HKD1_k127_3150459_9 transcription factor binding K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000142 266.0
HKD1_k127_3176496_0 CoA binding domain - - - 0.0 1175.0
HKD1_k127_3176496_1 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 5.868e-243 753.0
HKD1_k127_3176496_2 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 542.0
HKD1_k127_3176496_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 365.0
HKD1_k127_3176496_4 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002016 297.0
HKD1_k127_3176496_5 - - - - 0.0000000000000000000000000000000000000000000000424 182.0
HKD1_k127_3209442_0 Receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 349.0
HKD1_k127_3209442_1 COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain) - - - 0.00000000000001751 82.0
HKD1_k127_3227119_0 Aldo keto reductase - GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 435.0
HKD1_k127_3227119_1 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 396.0
HKD1_k127_3227119_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003938 286.0
HKD1_k127_3227119_3 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002755 279.0
HKD1_k127_3227119_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005833 248.0
HKD1_k127_3227119_5 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000001872 242.0
HKD1_k127_3227119_6 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000001788 225.0
HKD1_k127_3227119_7 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000000000000000000001367 162.0
HKD1_k127_3227119_8 - - - - 0.000000000000000000000000000000000001652 151.0
HKD1_k127_3257141_0 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 584.0
HKD1_k127_3257141_1 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000003564 152.0
HKD1_k127_3257141_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000002126 153.0
HKD1_k127_3257141_3 Four helix bundle sensory module for signal transduction - - - 0.0000000000000000000000003689 116.0
HKD1_k127_3257141_4 - - - - 0.00005727 54.0
HKD1_k127_3261456_0 AcrB/AcrD/AcrF family - - - 2.509e-233 757.0
HKD1_k127_3261456_1 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 615.0
HKD1_k127_3261456_10 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005513 268.0
HKD1_k127_3261456_11 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000008666 250.0
HKD1_k127_3261456_12 PFAM ABC transporter K09817 - - 0.000000000000000000000000000000000000000000001994 173.0
HKD1_k127_3261456_13 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000003337 187.0
HKD1_k127_3261456_14 Polysaccharide lyase family 4, domain II - - - 0.0000000000000000000000000000000000000000001808 168.0
HKD1_k127_3261456_15 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000005829 172.0
HKD1_k127_3261456_16 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000002547 150.0
HKD1_k127_3261456_17 Cytochrome C' - - - 0.00000000000000000000000000000000001077 145.0
HKD1_k127_3261456_18 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000002115 146.0
HKD1_k127_3261456_19 PFAM Carbohydrate-selective porin OprB - - - 0.00000000000000000000000000000002384 144.0
HKD1_k127_3261456_2 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 606.0
HKD1_k127_3261456_20 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000001743 108.0
HKD1_k127_3261456_21 Cytochrome C' - - - 0.000000000000000000246 97.0
HKD1_k127_3261456_22 Sporulation and spore germination - - - 0.0000000000000000002651 103.0
HKD1_k127_3261456_23 Iron dependent repressor, metal binding and dimerisation domain K09819,K11709,K19976 - - 0.00000000000000004404 91.0
HKD1_k127_3261456_24 - - - - 0.00000000002002 70.0
HKD1_k127_3261456_25 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000004949 73.0
HKD1_k127_3261456_27 YtkA-like - - - 0.0000186 52.0
HKD1_k127_3261456_28 transport - - - 0.0006915 53.0
HKD1_k127_3261456_3 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 540.0
HKD1_k127_3261456_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 428.0
HKD1_k127_3261456_5 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 376.0
HKD1_k127_3261456_6 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 319.0
HKD1_k127_3261456_7 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 309.0
HKD1_k127_3261456_8 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 295.0
HKD1_k127_3261456_9 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008479 278.0
HKD1_k127_3270042_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 5.975e-248 774.0
HKD1_k127_3270042_1 Protein of unknown function, DUF255 K06888 - - 1.479e-209 684.0
HKD1_k127_3270042_10 TIGRFAM anion transporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 324.0
HKD1_k127_3270042_11 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000000000000000000000000000000000000000000000000000000000000000109 248.0
HKD1_k127_3270042_12 - - - - 0.0000000000000000000000000000000000000000000000000000000121 226.0
HKD1_k127_3270042_13 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000001759 209.0
HKD1_k127_3270042_14 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000006751 203.0
HKD1_k127_3270042_15 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000001382 203.0
HKD1_k127_3270042_16 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000003426 175.0
HKD1_k127_3270042_17 Cytochrome P460 - - - 0.0000000000000000000000000000000000000000000001676 175.0
HKD1_k127_3270042_18 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000125 167.0
HKD1_k127_3270042_19 manganese ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000001619 161.0
HKD1_k127_3270042_2 - - - - 2.078e-197 638.0
HKD1_k127_3270042_20 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000007003 141.0
HKD1_k127_3270042_21 - - - - 0.00000000000000000000000006177 118.0
HKD1_k127_3270042_22 - - - - 0.00000000000000000001102 108.0
HKD1_k127_3270042_23 Cold shock protein domain - - - 0.0000000000000000001025 91.0
HKD1_k127_3270042_24 - - - - 0.0000000000000000002859 102.0
HKD1_k127_3270042_25 MacB-like periplasmic core domain - - - 0.00000000000000001323 90.0
HKD1_k127_3270042_26 lipopolysaccharide transmembrane transporter activity K07058,K18979 - 1.17.99.6 0.00000000000000001801 93.0
HKD1_k127_3270042_27 - - - - 0.000000000000003515 89.0
HKD1_k127_3270042_28 Polysaccharide biosynthesis protein - - - 0.000000000000003628 90.0
HKD1_k127_3270042_29 solute binding protein K02035 - - 0.00000000002478 74.0
HKD1_k127_3270042_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 577.0
HKD1_k127_3270042_30 - - - - 0.00000000006214 76.0
HKD1_k127_3270042_32 6-phosphogluconolactonase activity - - - 0.000000003019 69.0
HKD1_k127_3270042_33 Biotin carboxylase C-terminal domain K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3 0.000000004351 68.0
HKD1_k127_3270042_35 COG2755 Lysophospholipase L1 and related K10804 - 3.1.1.5 0.0000001071 63.0
HKD1_k127_3270042_36 GDSL-like Lipase/Acylhydrolase - - - 0.0000001179 63.0
HKD1_k127_3270042_37 Carboxypeptidase regulatory-like domain - - - 0.0000001894 64.0
HKD1_k127_3270042_38 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00001918 57.0
HKD1_k127_3270042_39 - - - - 0.00002798 48.0
HKD1_k127_3270042_4 Biotin carboxylase C-terminal domain K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 504.0
HKD1_k127_3270042_40 cellulase activity - - - 0.0000361 56.0
HKD1_k127_3270042_41 Hep Hag repeat protein K19233,K20276,K21449 - - 0.000105 54.0
HKD1_k127_3270042_42 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000227 53.0
HKD1_k127_3270042_43 Cell motility and secretion Intracellular trafficking and secretion - - - 0.0005898 51.0
HKD1_k127_3270042_44 Part of a membrane complex involved in electron transport K03616 - - 0.0006269 47.0
HKD1_k127_3270042_5 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 374.0
HKD1_k127_3270042_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 357.0
HKD1_k127_3270042_7 HMGL-like K01640 GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 342.0
HKD1_k127_3270042_8 glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 328.0
HKD1_k127_3270042_9 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 339.0
HKD1_k127_3273739_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000195 249.0
HKD1_k127_3273739_1 GYD domain - - - 0.000000000000000000002493 99.0
HKD1_k127_3273739_2 Abhydrolase domain containing 18 - - - 0.000000000000002767 77.0
HKD1_k127_3296898_0 DNA topological change K03168 - 5.99.1.2 5.173e-210 680.0
HKD1_k127_3296898_1 Protein of unknown function (DUF1800) - - - 4.675e-201 639.0
HKD1_k127_3296898_10 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00007814 47.0
HKD1_k127_3296898_11 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00014 49.0
HKD1_k127_3296898_2 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 535.0
HKD1_k127_3296898_3 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 509.0
HKD1_k127_3296898_4 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 492.0
HKD1_k127_3296898_5 Carboxylesterase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 402.0
HKD1_k127_3296898_6 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000001691 193.0
HKD1_k127_3296898_7 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000002454 198.0
HKD1_k127_3296898_8 - - - - 0.00000000000000000000000000000000000000001474 167.0
HKD1_k127_3296898_9 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00005286 53.0
HKD1_k127_3322453_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 353.0
HKD1_k127_3332384_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 3.296e-265 828.0
HKD1_k127_3332384_1 Amino acid permease - - - 3.398e-247 783.0
HKD1_k127_3332384_10 phosphorelay signal transduction system K02490 - - 0.00000000000000000000000000000000001825 156.0
HKD1_k127_3332384_11 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000008684 123.0
HKD1_k127_3332384_12 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000005354 104.0
HKD1_k127_3332384_13 GIY-YIG catalytic domain K07461 - - 0.000000000000000000001377 96.0
HKD1_k127_3332384_14 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000217 51.0
HKD1_k127_3332384_2 ammonium transporteR K03320 - - 2.02e-226 721.0
HKD1_k127_3332384_3 protein histidine kinase activity K11383 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 432.0
HKD1_k127_3332384_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 378.0
HKD1_k127_3332384_5 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 339.0
HKD1_k127_3332384_6 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 312.0
HKD1_k127_3332384_7 Two component transcriptional regulator, winged helix family K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 310.0
HKD1_k127_3332384_8 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000004451 239.0
HKD1_k127_3332384_9 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751,K04752 - - 0.0000000000000000000000000000000000001576 144.0
HKD1_k127_335338_0 alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 4.756e-258 805.0
HKD1_k127_335338_1 Dehydrogenase K00114 - 1.1.2.8 4.344e-221 700.0
HKD1_k127_335338_2 Amidohydrolase K22213 - 4.1.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009213 319.0
HKD1_k127_335338_3 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002064 251.0
HKD1_k127_335338_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000007626 207.0
HKD1_k127_335338_5 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000119 194.0
HKD1_k127_335338_7 Transposase, Mutator family - - - 0.000000000000000001163 89.0
HKD1_k127_346025_0 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 594.0
HKD1_k127_346025_1 Inorganic ion transport and metabolism K03319 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 467.0
HKD1_k127_346025_2 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D K01424,K05597 GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0032787,GO:0034641,GO:0042597,GO:0042802,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1,3.5.1.38 0.0000000000000000000000000000000000000000000000000000000008324 206.0
HKD1_k127_3511332_0 Major facilitator Superfamily K03292,K16248 - - 8.582e-212 671.0
HKD1_k127_3511332_1 hydrolase, family 3 K05349 - 3.2.1.21 5.358e-209 659.0
HKD1_k127_3511332_2 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 527.0
HKD1_k127_3535356_0 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 368.0
HKD1_k127_3535356_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 298.0
HKD1_k127_3535356_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000008681 164.0
HKD1_k127_3579754_0 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 333.0
HKD1_k127_3579754_1 - - - - 0.000000000000000000000000000000000000000000000001954 188.0
HKD1_k127_3579754_2 - - - - 0.000000000000000000000000000000000000000004704 162.0
HKD1_k127_3579754_3 Hep Hag repeat protein - - - 0.000000006852 67.0
HKD1_k127_3602437_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1497.0
HKD1_k127_3602437_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1212.0
HKD1_k127_3602437_10 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 351.0
HKD1_k127_3602437_11 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 331.0
HKD1_k127_3602437_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002929 291.0
HKD1_k127_3602437_13 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003592 254.0
HKD1_k127_3602437_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000291 198.0
HKD1_k127_3602437_15 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000002176 197.0
HKD1_k127_3602437_16 - - - - 0.000000000000000000000000000000000000000000009094 171.0
HKD1_k127_3602437_17 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000005666 166.0
HKD1_k127_3602437_18 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000224 141.0
HKD1_k127_3602437_19 helix_turn_helix, mercury resistance K19591 - - 0.00000000000000000000000000001341 122.0
HKD1_k127_3602437_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1074.0
HKD1_k127_3602437_20 - - - - 0.0000000000000000000000000007647 133.0
HKD1_k127_3602437_21 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000001171 113.0
HKD1_k127_3602437_22 - - - - 0.00000000000000000000003284 101.0
HKD1_k127_3602437_23 OmpA family K03640 - - 0.0000000000000000000007888 96.0
HKD1_k127_3602437_24 - - - - 0.000000000000000000001133 101.0
HKD1_k127_3602437_25 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000005759 81.0
HKD1_k127_3602437_3 Glycosyl hydrolase family 57 - - - 8.503e-321 999.0
HKD1_k127_3602437_4 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 3.596e-194 633.0
HKD1_k127_3602437_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 539.0
HKD1_k127_3602437_6 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 391.0
HKD1_k127_3602437_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 390.0
HKD1_k127_3602437_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 386.0
HKD1_k127_3602437_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 383.0
HKD1_k127_3613522_0 Dehydrogenase K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 591.0
HKD1_k127_3613522_1 Aldo/keto reductase family K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 404.0
HKD1_k127_3613522_10 cytochrome c K00368 - 1.7.2.1 0.000000000000000000000001591 109.0
HKD1_k127_3613522_11 Patatin-like phospholipase - - - 0.000000000000000000000003502 119.0
HKD1_k127_3613522_12 YCII-related domain - - - 0.0000000000000000000007256 109.0
HKD1_k127_3613522_13 Domain of unknown function (DUF4198) - - - 0.0000000000000000005382 98.0
HKD1_k127_3613522_14 - - - - 0.000000000000000001075 100.0
HKD1_k127_3613522_15 Cytochrome c - - - 0.000000000000000002333 98.0
HKD1_k127_3613522_16 Outer membrane protein beta-barrel domain - - - 0.000000000000000002631 94.0
HKD1_k127_3613522_17 ankyrin repeat - - - 0.0000000000000001326 93.0
HKD1_k127_3613522_18 - - - - 0.000000000000000231 91.0
HKD1_k127_3613522_19 lactoylglutathione lyase activity - - - 0.0000000001068 68.0
HKD1_k127_3613522_2 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 357.0
HKD1_k127_3613522_21 Disease resistance protein - - - 0.0001349 53.0
HKD1_k127_3613522_3 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000013 231.0
HKD1_k127_3613522_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000003876 212.0
HKD1_k127_3613522_5 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000002793 195.0
HKD1_k127_3613522_6 Cupin 2, conserved barrel domain protein K06720 - 4.2.1.108 0.00000000000000000000000000000000000000000000000001187 190.0
HKD1_k127_3613522_7 Cytochrome c mono- and diheme variants - - - 0.000000000000000000000000000000002682 143.0
HKD1_k127_3613522_8 Transcriptional regulator - - - 0.00000000000000000000000000000008363 134.0
HKD1_k127_3613522_9 - - - - 0.00000000000000000000000001826 120.0
HKD1_k127_3638870_0 AcrB/AcrD/AcrF family - - - 0.0 1173.0
HKD1_k127_3638870_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 2.103e-217 705.0
HKD1_k127_3638870_10 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 412.0
HKD1_k127_3638870_11 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 361.0
HKD1_k127_3638870_12 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 357.0
HKD1_k127_3638870_13 COG3959 Transketolase, N-terminal subunit K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 345.0
HKD1_k127_3638870_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 329.0
HKD1_k127_3638870_15 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000511 278.0
HKD1_k127_3638870_16 Belongs to the PdxA family K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000001592 275.0
HKD1_k127_3638870_17 Fad dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003825 271.0
HKD1_k127_3638870_18 Phosphomethylpyrimidine kinase K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000002607 267.0
HKD1_k127_3638870_19 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000001273 245.0
HKD1_k127_3638870_2 TIGRFAM Aspartate kinase K12524 - 1.1.1.3,2.7.2.4 1.352e-214 694.0
HKD1_k127_3638870_20 PFAM PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001652 224.0
HKD1_k127_3638870_21 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.0000000000000000000000000000000000000000000000000000000002798 215.0
HKD1_k127_3638870_22 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000002384 211.0
HKD1_k127_3638870_23 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000008253 194.0
HKD1_k127_3638870_24 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000134 218.0
HKD1_k127_3638870_25 - - - - 0.00000000000000000000000000000000000000000000000000003998 209.0
HKD1_k127_3638870_26 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000008623 190.0
HKD1_k127_3638870_27 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000007091 203.0
HKD1_k127_3638870_28 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000003188 190.0
HKD1_k127_3638870_29 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000000000000000000000003158 186.0
HKD1_k127_3638870_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 556.0
HKD1_k127_3638870_30 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.0000000000000000000000000000000000000000000006328 181.0
HKD1_k127_3638870_31 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000002095 176.0
HKD1_k127_3638870_32 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000001103 161.0
HKD1_k127_3638870_33 Protein of unknown function (DUF1698) - - - 0.0000000000000000000000000000000001312 145.0
HKD1_k127_3638870_34 DNA polymerase III, delta' K02341 - 2.7.7.7 0.000000000000000000000000000000006251 143.0
HKD1_k127_3638870_35 Universal stress protein family - - - 0.00000000000000000000000000001164 129.0
HKD1_k127_3638870_36 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000002933 131.0
HKD1_k127_3638870_37 TIGRFAM TonB family protein K03832 - - 0.00000000000000000000000000004339 127.0
HKD1_k127_3638870_38 PFAM transcriptional regulator PadR family protein - - - 0.0000000000000000000000000006561 117.0
HKD1_k127_3638870_39 - - - - 0.000000000000000000000000001503 123.0
HKD1_k127_3638870_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 503.0
HKD1_k127_3638870_40 protein TIM barrel - - - 0.000000000000000000000000008468 127.0
HKD1_k127_3638870_41 - - - - 0.00000000000000000000000002596 119.0
HKD1_k127_3638870_42 aspartic-type endopeptidase activity K06985 - - 0.00000000000000000000000144 117.0
HKD1_k127_3638870_43 - - - - 0.00000000000000000000003534 103.0
HKD1_k127_3638870_44 - - - - 0.000000000000000000001415 109.0
HKD1_k127_3638870_46 Universal stress protein K06149 - - 0.00000000000000005126 87.0
HKD1_k127_3638870_47 Phospholipid methyltransferase - - - 0.0000000000000001852 86.0
HKD1_k127_3638870_48 Ig-like domain from next to BRCA1 gene - - - 0.00000000000001927 85.0
HKD1_k127_3638870_49 Prokaryotic cytochrome b561 - - - 0.00000000009686 72.0
HKD1_k127_3638870_5 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 476.0
HKD1_k127_3638870_51 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001417 56.0
HKD1_k127_3638870_52 MgsA AAA+ ATPase C terminal K07478 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0002022 53.0
HKD1_k127_3638870_54 - - - - 0.0006136 52.0
HKD1_k127_3638870_6 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 437.0
HKD1_k127_3638870_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 439.0
HKD1_k127_3638870_8 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 447.0
HKD1_k127_3638870_9 COG1680 Beta-lactamase class C and other penicillin binding proteins K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 393.0
HKD1_k127_3657024_0 TonB-dependent Receptor Plug K02014 - - 4.72e-301 964.0
HKD1_k127_3657024_1 PFAM type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 519.0
HKD1_k127_3657024_10 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 333.0
HKD1_k127_3657024_11 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004085 275.0
HKD1_k127_3657024_12 response regulator K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002843 253.0
HKD1_k127_3657024_13 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000002778 226.0
HKD1_k127_3657024_14 palmitoyl-(protein) hydrolase activity K06999,K15975 - - 0.000000000000000000000000000000000000000000000000000000000000218 236.0
HKD1_k127_3657024_15 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000005623 232.0
HKD1_k127_3657024_16 PFAM type II secretion system K12510 - - 0.0000000000000000000000000000000000000000000000000001073 200.0
HKD1_k127_3657024_17 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000004533 196.0
HKD1_k127_3657024_18 type II secretion system K12511 - - 0.000000000000000000000000000000000000000000005813 184.0
HKD1_k127_3657024_19 Domain of unknown function (DUF1990) - - - 0.000000000000000000000000000000000000000007752 160.0
HKD1_k127_3657024_2 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 473.0
HKD1_k127_3657024_20 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000002763 157.0
HKD1_k127_3657024_21 - - - - 0.000000000000000000000000000000000000001442 158.0
HKD1_k127_3657024_22 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000007573 149.0
HKD1_k127_3657024_23 PFAM SAF domain K02279 - - 0.000000000000000000000000000000000000007614 156.0
HKD1_k127_3657024_24 OmpA family - - - 0.00000000000000000000000000000000007499 142.0
HKD1_k127_3657024_25 - - - - 0.0000000000000000000000000000000000964 143.0
HKD1_k127_3657024_26 - - - - 0.000000000000000000000000000006479 132.0
HKD1_k127_3657024_27 AAA domain K02282 - - 0.00000000000000000000000000001062 132.0
HKD1_k127_3657024_28 FecR protein - - - 0.0000000000000000000000000001886 119.0
HKD1_k127_3657024_29 positive regulation of growth rate - GO:0003674,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0030955,GO:0031420,GO:0035864,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896 - 0.0000000000000000000000000001902 119.0
HKD1_k127_3657024_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 432.0
HKD1_k127_3657024_30 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000002044 132.0
HKD1_k127_3657024_31 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000002137 121.0
HKD1_k127_3657024_32 - - - - 0.00000000000000000000000005183 118.0
HKD1_k127_3657024_33 Protein conserved in bacteria K07114 - - 0.00000000000000000000002117 116.0
HKD1_k127_3657024_34 Type IV leader peptidase family K02278 - 3.4.23.43 0.0000000000000000000000224 107.0
HKD1_k127_3657024_35 - - - - 0.00000000000000000000007116 110.0
HKD1_k127_3657024_36 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000002923 92.0
HKD1_k127_3657024_37 Putative Flp pilus-assembly TadE/G-like - - - 0.000000003133 71.0
HKD1_k127_3657024_38 PFAM TadE family protein - - - 0.000000005 67.0
HKD1_k127_3657024_39 - - - - 0.000007489 54.0
HKD1_k127_3657024_4 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 423.0
HKD1_k127_3657024_40 Flp/Fap pilin component K02651 - - 0.00005647 50.0
HKD1_k127_3657024_41 TPR repeat-containing protein - - - 0.00006017 53.0
HKD1_k127_3657024_42 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0001546 54.0
HKD1_k127_3657024_43 - - - - 0.0002045 50.0
HKD1_k127_3657024_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 414.0
HKD1_k127_3657024_6 Chase2 domain K01768,K07814 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 432.0
HKD1_k127_3657024_7 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 392.0
HKD1_k127_3657024_8 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 384.0
HKD1_k127_3657024_9 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 371.0
HKD1_k127_367289_0 Cytochrome c - - - 0.0 1094.0
HKD1_k127_367289_1 Glycosyl transferases group 1 - - - 3.742e-280 897.0
HKD1_k127_367289_10 Belongs to the peptidase S8 family - - - 2.651e-197 628.0
HKD1_k127_367289_11 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 607.0
HKD1_k127_367289_12 IgA Peptidase M64 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 612.0
HKD1_k127_367289_13 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 582.0
HKD1_k127_367289_14 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 518.0
HKD1_k127_367289_15 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 475.0
HKD1_k127_367289_16 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 469.0
HKD1_k127_367289_17 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 463.0
HKD1_k127_367289_18 Amino acid permease K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 451.0
HKD1_k127_367289_19 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 442.0
HKD1_k127_367289_2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 3.892e-251 810.0
HKD1_k127_367289_20 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 440.0
HKD1_k127_367289_21 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 427.0
HKD1_k127_367289_22 Queuosine biosynthesis protein K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 418.0
HKD1_k127_367289_23 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 392.0
HKD1_k127_367289_24 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 406.0
HKD1_k127_367289_25 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 382.0
HKD1_k127_367289_26 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 373.0
HKD1_k127_367289_27 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 327.0
HKD1_k127_367289_28 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 299.0
HKD1_k127_367289_29 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 280.0
HKD1_k127_367289_3 Sigma-54 interaction domain K15836 - - 5.066e-240 760.0
HKD1_k127_367289_30 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004157 276.0
HKD1_k127_367289_31 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007415 243.0
HKD1_k127_367289_32 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000002508 242.0
HKD1_k127_367289_33 Peptidoglycan-binding domain 1 protein K01207,K01447,K03806,K11066 - 3.2.1.52,3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000289 242.0
HKD1_k127_367289_34 polysaccharide catabolic process K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000006925 229.0
HKD1_k127_367289_35 Short-chain Dehydrogenase reductase - - - 0.0000000000000000000000000000000000000000000000000000000000008575 218.0
HKD1_k127_367289_36 MerR, DNA binding K13639 - - 0.00000000000000000000000000000000000000000000000000000000001674 210.0
HKD1_k127_367289_37 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000001534 210.0
HKD1_k127_367289_38 - - - - 0.000000000000000000000000000000000000000000000000000007328 199.0
HKD1_k127_367289_39 homoserine kinase activity K18844 - - 0.000000000000000000000000000000000000000000000000000007708 214.0
HKD1_k127_367289_4 WD40-like Beta Propeller Repeat - - - 7.896e-227 738.0
HKD1_k127_367289_40 response to copper ion K01187,K16915 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000001584 201.0
HKD1_k127_367289_41 - - - - 0.0000000000000000000000000000000000000000000000000000878 205.0
HKD1_k127_367289_42 LysM domain - - - 0.0000000000000000000000000000000000000000000000006907 183.0
HKD1_k127_367289_43 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000002135 190.0
HKD1_k127_367289_44 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000001181 165.0
HKD1_k127_367289_45 - - - - 0.00000000000000000000000000000000000000002937 160.0
HKD1_k127_367289_46 - - - - 0.0000000000000000000000000000000000002453 154.0
HKD1_k127_367289_47 - - - - 0.000000000000000000000000000000000001195 160.0
HKD1_k127_367289_48 - - - - 0.0000000000000000000000000000000003017 151.0
HKD1_k127_367289_49 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000004779 146.0
HKD1_k127_367289_5 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 4.714e-218 687.0
HKD1_k127_367289_50 Protein of unknown function (DUF3303) - - - 0.000000000000000000000000000000009174 136.0
HKD1_k127_367289_51 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.0000000000000000000000000000001545 139.0
HKD1_k127_367289_52 Haem-degrading - - - 0.0000000000000000000000000009218 121.0
HKD1_k127_367289_53 - - - - 0.000000000000000000000000003172 123.0
HKD1_k127_367289_54 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000001515 113.0
HKD1_k127_367289_55 Sulphur transport K07112 - - 0.0000000000000000000000005947 109.0
HKD1_k127_367289_56 - - - - 0.000000000000000000001227 108.0
HKD1_k127_367289_57 PFAM YeeE YedE family (DUF395) K07112 - - 0.000000000000000000002327 101.0
HKD1_k127_367289_58 Glycosyl transferases group 1 - - - 0.0000000000000000000216 106.0
HKD1_k127_367289_6 Cytochrome c - - - 1.089e-217 732.0
HKD1_k127_367289_60 - K09004 - - 0.0000000000000000003503 97.0
HKD1_k127_367289_61 Amidohydrolase family - - - 0.000000000000000001055 100.0
HKD1_k127_367289_62 PFAM Glycosyl transferases group 1 K20444 - - 0.000000000000000002608 100.0
HKD1_k127_367289_63 Chalcone isomerase-like - - - 0.00000000000000001047 92.0
HKD1_k127_367289_64 Invasin, domain 3 K13735 - - 0.0000000000000002003 94.0
HKD1_k127_367289_65 23S rRNA-intervening sequence protein - - - 0.0000000000000008993 81.0
HKD1_k127_367289_66 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate - - - 0.00000000000002116 78.0
HKD1_k127_367289_67 - - - - 0.00000000002975 68.0
HKD1_k127_367289_68 protein conserved in bacteria K09796 - - 0.0000000003247 66.0
HKD1_k127_367289_69 cellulose synthase operon C domain protein K20543 - - 0.0000000005719 72.0
HKD1_k127_367289_7 Bacterial protein of unknown function (DUF853) K06915 - - 8.304e-214 675.0
HKD1_k127_367289_70 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.000000001078 71.0
HKD1_k127_367289_71 - - - - 0.000000001132 69.0
HKD1_k127_367289_72 Methyltransferase domain - - - 0.000002531 61.0
HKD1_k127_367289_73 Phosphopantetheine attachment site - - - 0.000005795 60.0
HKD1_k127_367289_74 - - - - 0.000006165 53.0
HKD1_k127_367289_75 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000009837 57.0
HKD1_k127_367289_76 Cytochrome c - - - 0.00001219 52.0
HKD1_k127_367289_77 SnoaL-like domain - - - 0.00001526 54.0
HKD1_k127_367289_8 COG COG1132 ABC-type multidrug transport system ATPase and permease components Defense mechanisms K06147 - - 2.165e-204 654.0
HKD1_k127_367289_9 Bacterial protein of unknown function (DUF885) - - - 1.324e-203 652.0
HKD1_k127_3725043_0 Carboxypeptidase regulatory-like domain - - - 0.0 1118.0
HKD1_k127_3725043_1 ABC-type multidrug transport system ATPase and permease K06147,K06148 - - 1.853e-273 852.0
HKD1_k127_3725043_10 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 583.0
HKD1_k127_3725043_11 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 576.0
HKD1_k127_3725043_12 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 571.0
HKD1_k127_3725043_13 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 586.0
HKD1_k127_3725043_14 Aldehyde dehydrogenase family K13922,K18119 - 1.2.1.76,1.2.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 430.0
HKD1_k127_3725043_15 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 414.0
HKD1_k127_3725043_16 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 356.0
HKD1_k127_3725043_17 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 331.0
HKD1_k127_3725043_18 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 327.0
HKD1_k127_3725043_19 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 340.0
HKD1_k127_3725043_2 ABC-type multidrug transport system ATPase and permease K06147 - - 2.767e-267 836.0
HKD1_k127_3725043_20 PFAM Aspartate glutamate uridylate kinase K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 310.0
HKD1_k127_3725043_21 TOBE domain K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 309.0
HKD1_k127_3725043_22 Molybdate ABC transporter K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006436 284.0
HKD1_k127_3725043_23 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003952 283.0
HKD1_k127_3725043_24 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000009628 265.0
HKD1_k127_3725043_25 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004279 279.0
HKD1_k127_3725043_26 phosphoprotein phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001359 249.0
HKD1_k127_3725043_27 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009669 247.0
HKD1_k127_3725043_28 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000002978 247.0
HKD1_k127_3725043_29 Flagellar Assembly Protein A K09749 - - 0.00000000000000000000000000000000000000000000000000008414 202.0
HKD1_k127_3725043_3 Belongs to the peptidase S16 family - - - 7.961e-255 810.0
HKD1_k127_3725043_30 - - - - 0.0000000000000000000000000000000000000000000000000178 192.0
HKD1_k127_3725043_31 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000002705 195.0
HKD1_k127_3725043_32 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000001484 192.0
HKD1_k127_3725043_33 Protein of unknown function (DUF1698) K15257 - - 0.00000000000000000000000000000000000000000001276 171.0
HKD1_k127_3725043_34 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000001918 162.0
HKD1_k127_3725043_35 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000007812 149.0
HKD1_k127_3725043_36 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000001052 151.0
HKD1_k127_3725043_38 TOBE domain - - - 0.000000000000000000000000000005322 124.0
HKD1_k127_3725043_4 Belongs to the ClpA ClpB family K03694 - - 7.493e-247 784.0
HKD1_k127_3725043_40 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000001654 106.0
HKD1_k127_3725043_41 deacetylase K22278 - 3.5.1.104 0.000000000000000000000004887 111.0
HKD1_k127_3725043_42 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000005522 101.0
HKD1_k127_3725043_43 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000009831 94.0
HKD1_k127_3725043_44 PFAM Cytochrome c, class I K02030 - - 0.000000000001062 81.0
HKD1_k127_3725043_5 DNA topological change K03168 - 5.99.1.2 6.846e-233 791.0
HKD1_k127_3725043_6 DNA polymerase beta thumb K02347 - - 8.874e-227 719.0
HKD1_k127_3725043_7 PQQ-like domain - - - 1.838e-226 719.0
HKD1_k127_3725043_8 Belongs to the RtcB family K14415 - 6.5.1.3 8.303e-219 689.0
HKD1_k127_3725043_9 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 621.0
HKD1_k127_3759665_0 Carboxypeptidase regulatory-like domain - - - 3.679e-305 966.0
HKD1_k127_3759665_1 oxidoreductase activity - - - 1.427e-252 820.0
HKD1_k127_3759665_2 Peptidase M56, BlaR1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 406.0
HKD1_k127_3759665_3 - K02172 - - 0.00000000000000000000000000000000000000000000000000004899 198.0
HKD1_k127_3759665_4 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000000000002993 179.0
HKD1_k127_3838386_0 peptidyl-tyrosine sulfation K01277 - 3.4.14.4 5.606e-287 898.0
HKD1_k127_3838386_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 1.465e-225 729.0
HKD1_k127_3838386_10 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 412.0
HKD1_k127_3838386_11 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 399.0
HKD1_k127_3838386_12 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 394.0
HKD1_k127_3838386_13 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 384.0
HKD1_k127_3838386_14 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 363.0
HKD1_k127_3838386_15 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 366.0
HKD1_k127_3838386_16 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 355.0
HKD1_k127_3838386_17 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 311.0
HKD1_k127_3838386_18 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001103 283.0
HKD1_k127_3838386_19 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005287 282.0
HKD1_k127_3838386_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 4.951e-213 684.0
HKD1_k127_3838386_20 Molybdopterin dehydrogenase K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000005285 278.0
HKD1_k127_3838386_21 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005563 284.0
HKD1_k127_3838386_22 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000006439 256.0
HKD1_k127_3838386_23 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000008605 200.0
HKD1_k127_3838386_24 AAA domain K02450 - - 0.0000000000000000000000000000000000000000000000000000139 212.0
HKD1_k127_3838386_25 2Fe-2S -binding domain protein K13483 - - 0.00000000000000000000000000000000000000000000000000004773 194.0
HKD1_k127_3838386_26 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000004275 206.0
HKD1_k127_3838386_27 TIGRFAM CitB domain protein K13795 - - 0.000000000000000000000000000000000000000000000000008599 186.0
HKD1_k127_3838386_28 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000008064 184.0
HKD1_k127_3838386_29 Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000222 174.0
HKD1_k127_3838386_3 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 634.0
HKD1_k127_3838386_30 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000396 157.0
HKD1_k127_3838386_31 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000002906 151.0
HKD1_k127_3838386_32 Sigma-70, region 4 K02405 - - 0.0000000000000000000000000000000000003437 152.0
HKD1_k127_3838386_33 Belongs to the ompA family - - - 0.000000000000000000000000006127 120.0
HKD1_k127_3838386_34 PFAM von Willebrand factor type A - - - 0.000000000000000000000004123 113.0
HKD1_k127_3838386_35 Protein of unknown function (DUF1326) - - - 0.00000000000000000001244 100.0
HKD1_k127_3838386_36 CHRD domain - - - 0.0000000003209 68.0
HKD1_k127_3838386_37 PFAM amino acid-binding ACT domain protein - - - 0.000000002646 64.0
HKD1_k127_3838386_38 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000343 70.0
HKD1_k127_3838386_39 - - - - 0.00000008962 62.0
HKD1_k127_3838386_4 FAD dependent oxidoreductase K13796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 612.0
HKD1_k127_3838386_40 - - - - 0.000003562 53.0
HKD1_k127_3838386_41 Putative beta-barrel porin 2 - - - 0.00001503 57.0
HKD1_k127_3838386_42 Stress responsive A/B Barrel Domain - - - 0.00004781 50.0
HKD1_k127_3838386_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 550.0
HKD1_k127_3838386_6 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 550.0
HKD1_k127_3838386_7 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 495.0
HKD1_k127_3838386_8 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 430.0
HKD1_k127_3838386_9 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 406.0
HKD1_k127_385918_0 Malate synthase K01638 - 2.3.3.9 1.35e-297 936.0
HKD1_k127_385918_1 DNA topological change K03168 - 5.99.1.2 4.153e-235 756.0
HKD1_k127_385918_10 Ankyrin repeats (many copies) - - - 0.0000000000000000000000000000000000000000000002878 189.0
HKD1_k127_385918_11 - - - - 0.0000000000000000000000000000000004711 144.0
HKD1_k127_385918_12 alginic acid biosynthetic process - - - 0.000000000000000000000000000000008701 144.0
HKD1_k127_385918_2 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009553 416.0
HKD1_k127_385918_3 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 391.0
HKD1_k127_385918_4 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 357.0
HKD1_k127_385918_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 329.0
HKD1_k127_385918_6 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000595 290.0
HKD1_k127_385918_7 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005451 255.0
HKD1_k127_385918_8 Aspartyl Asparaginyl beta-hydroxylase K00476,K12979 - 1.14.11.16 0.000000000000000000000000000000000000000000000000000000000000002621 226.0
HKD1_k127_385918_9 Peptidase inhibitor I9 - - - 0.0000000000000000000000000000000000000000000000000002233 201.0
HKD1_k127_3951477_0 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 557.0
HKD1_k127_3951477_1 Subtilase family - - - 0.000000000000000000001211 94.0
HKD1_k127_3982047_0 Serine hydrolase involved in the detoxification of formaldehyde - - - 9.416e-246 771.0
HKD1_k127_3982047_1 Aminomethyltransferase folate-binding domain K15064 - - 8.086e-241 752.0
HKD1_k127_3982047_10 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 488.0
HKD1_k127_3982047_11 Uncharacterised MFS-type transporter YbfB K05548,K05819,K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 473.0
HKD1_k127_3982047_12 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007508 471.0
HKD1_k127_3982047_13 penicillin binding K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 499.0
HKD1_k127_3982047_14 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 374.0
HKD1_k127_3982047_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 379.0
HKD1_k127_3982047_16 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 389.0
HKD1_k127_3982047_17 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 355.0
HKD1_k127_3982047_18 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 351.0
HKD1_k127_3982047_19 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 348.0
HKD1_k127_3982047_2 Alpha-2-Macroglobulin K06894 - - 4.819e-232 788.0
HKD1_k127_3982047_20 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 345.0
HKD1_k127_3982047_21 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 356.0
HKD1_k127_3982047_22 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 327.0
HKD1_k127_3982047_23 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 313.0
HKD1_k127_3982047_24 Flavodoxin-like fold K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 304.0
HKD1_k127_3982047_25 LssY C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 295.0
HKD1_k127_3982047_26 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007105 286.0
HKD1_k127_3982047_27 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001611 295.0
HKD1_k127_3982047_28 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008364 282.0
HKD1_k127_3982047_29 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005654 278.0
HKD1_k127_3982047_3 DNA topological change K03168 - 5.99.1.2 1.268e-222 716.0
HKD1_k127_3982047_30 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007202 274.0
HKD1_k127_3982047_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000017 264.0
HKD1_k127_3982047_32 COG3911 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006616 243.0
HKD1_k127_3982047_33 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000007257 253.0
HKD1_k127_3982047_34 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001011 263.0
HKD1_k127_3982047_35 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000013 204.0
HKD1_k127_3982047_36 - - - - 0.00000000000000000000000000000000000000000000000000002287 200.0
HKD1_k127_3982047_37 - - - - 0.000000000000000000000000000000000000000000000000001793 194.0
HKD1_k127_3982047_38 Belongs to the UPF0311 family - - - 0.00000000000000000000000000000000000000000000005791 176.0
HKD1_k127_3982047_39 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000000000000000000000001069 171.0
HKD1_k127_3982047_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20940 - 1.14.13.218 1.705e-216 683.0
HKD1_k127_3982047_40 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000001016 175.0
HKD1_k127_3982047_41 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000002547 170.0
HKD1_k127_3982047_42 phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000751 158.0
HKD1_k127_3982047_43 - - - - 0.00000000000000000000000000000000000009616 153.0
HKD1_k127_3982047_44 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000002505 147.0
HKD1_k127_3982047_45 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000002609 150.0
HKD1_k127_3982047_46 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000618 144.0
HKD1_k127_3982047_47 - - - - 0.00000000000000000000000000000000265 141.0
HKD1_k127_3982047_48 Low molecular weight phosphotyrosine protein phosphatase - - - 0.00000000000000000000000000000001663 144.0
HKD1_k127_3982047_49 - - - - 0.00000000000000000000000000000002421 134.0
HKD1_k127_3982047_5 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 625.0
HKD1_k127_3982047_50 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000002665 133.0
HKD1_k127_3982047_51 transcriptional regulator, ArsR family protein K03892 - - 0.00000000000000000000003872 106.0
HKD1_k127_3982047_52 - - - - 0.000000000000000000002132 106.0
HKD1_k127_3982047_53 - - - - 0.0000000000000000001258 96.0
HKD1_k127_3982047_55 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000005845 99.0
HKD1_k127_3982047_56 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000005396 96.0
HKD1_k127_3982047_57 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 0.00000000000001297 82.0
HKD1_k127_3982047_58 - - - - 0.0000000000008347 74.0
HKD1_k127_3982047_59 antisigma factor binding - - - 0.000000000009004 76.0
HKD1_k127_3982047_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 580.0
HKD1_k127_3982047_61 - - - - 0.000000000807 66.0
HKD1_k127_3982047_62 Coagulation factor 5 8 type domain protein - - - 0.000000000884 70.0
HKD1_k127_3982047_63 Cytochrome c K17760 - 1.1.9.1 0.00000003948 66.0
HKD1_k127_3982047_64 Carboxypeptidase regulatory-like domain - - - 0.000002125 55.0
HKD1_k127_3982047_65 - - - - 0.00002231 57.0
HKD1_k127_3982047_67 Prokaryotic N-terminal methylation motif K02456 - - 0.0001185 53.0
HKD1_k127_3982047_68 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0001436 53.0
HKD1_k127_3982047_7 Tannase and feruloyl esterase K21105 - 3.1.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 574.0
HKD1_k127_3982047_8 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 558.0
HKD1_k127_3982047_9 Belongs to the TPP enzyme family K01576,K01652 - 2.2.1.6,4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 531.0
HKD1_k127_3993382_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.34e-231 727.0
HKD1_k127_3993382_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 370.0
HKD1_k127_3993382_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001736 255.0
HKD1_k127_3993382_3 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000001925 219.0
HKD1_k127_3993382_4 ErfK YbiS YcfS YnhG family protein K21470 - - 0.000000000000000004831 93.0
HKD1_k127_3993382_5 Putative esterase - - - 0.0000003717 61.0
HKD1_k127_3993382_6 Carboxymuconolactone decarboxylase family - - - 0.0002243 51.0
HKD1_k127_4020842_0 Phosphoenolpyruvate phosphomutase K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 340.0
HKD1_k127_4020842_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003458 287.0
HKD1_k127_4020842_10 - - - - 0.000000000000000002162 93.0
HKD1_k127_4020842_11 - - - - 0.000000000000307 80.0
HKD1_k127_4020842_12 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.000000000004507 72.0
HKD1_k127_4020842_13 lactoylglutathione lyase activity - - - 0.0000000002832 64.0
HKD1_k127_4020842_14 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000001436 68.0
HKD1_k127_4020842_15 alpha/beta hydrolase fold - - - 0.000004319 50.0
HKD1_k127_4020842_16 CAAX protease self-immunity K07052 - - 0.0004026 45.0
HKD1_k127_4020842_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002359 271.0
HKD1_k127_4020842_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001035 253.0
HKD1_k127_4020842_4 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000002797 220.0
HKD1_k127_4020842_5 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000009327 199.0
HKD1_k127_4020842_6 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.00000000000000000000000000000000000000005387 162.0
HKD1_k127_4020842_7 Acetyltransferase (GNAT) domain K03824 - - 0.0000000000000000000000000000000000000002504 154.0
HKD1_k127_4020842_8 DinB superfamily K07552 - - 0.000000000000000000000000243 111.0
HKD1_k127_4022755_0 ASPIC and UnbV - - - 2.981e-267 850.0
HKD1_k127_4022755_1 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 1.994e-205 650.0
HKD1_k127_4022755_10 Anthranilate synthase component I, N terminal region K01657,K01665 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 425.0
HKD1_k127_4022755_11 Fungalysin metallopeptidase (M36) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 364.0
HKD1_k127_4022755_12 Glucose / Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 347.0
HKD1_k127_4022755_13 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 349.0
HKD1_k127_4022755_14 Dehydrogenase K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 329.0
HKD1_k127_4022755_15 curli production assembly transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 307.0
HKD1_k127_4022755_16 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016787,GO:0016810,GO:0016814,GO:0018759,GO:0019238,GO:0043446,GO:0044237,GO:0044424,GO:0044464,GO:0071704 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 318.0
HKD1_k127_4022755_17 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 294.0
HKD1_k127_4022755_18 Belongs to the RimK family K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004623 271.0
HKD1_k127_4022755_19 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001654 261.0
HKD1_k127_4022755_2 PQQ-like domain - - - 1.428e-200 644.0
HKD1_k127_4022755_20 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003041 264.0
HKD1_k127_4022755_21 FAD linked oxidases, C-terminal domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000105 247.0
HKD1_k127_4022755_22 transferase activity, transferring glycosyl groups K06984 - 2.4.2.54 0.00000000000000000000000000000000000000000000000000000000000000288 233.0
HKD1_k127_4022755_23 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.000000000000000000000000000000000000000000000000000000000000004586 237.0
HKD1_k127_4022755_24 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000006372 239.0
HKD1_k127_4022755_25 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.00000000000000000000000000000000000000000000000000000000046 230.0
HKD1_k127_4022755_26 lactoylglutathione lyase activity K03088 - - 0.0000000000000000000000000000000000000000000000000000001283 205.0
HKD1_k127_4022755_27 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000001614 197.0
HKD1_k127_4022755_28 formylmethanofuran dehydrogenase activity K00202 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.0000000000000000000000000000000000000000000001023 183.0
HKD1_k127_4022755_29 Protein of unknown function (DUF447) K09154 - - 0.0000000000000000000000000000000000000000000001642 178.0
HKD1_k127_4022755_3 Metallo-beta-lactamase superfamily - - - 2.17e-196 629.0
HKD1_k127_4022755_30 Pterin 4 alpha carbinolamine dehydratase K01724,K11991 - 3.5.4.33,4.2.1.96 0.000000000000000000000000000000000000000000009231 166.0
HKD1_k127_4022755_31 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000232 168.0
HKD1_k127_4022755_32 AAA domain K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.0000000000000000000000000000000000000000008319 177.0
HKD1_k127_4022755_33 acetyltransferase - - - 0.00000000000000000000000000000000000000001317 177.0
HKD1_k127_4022755_34 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000831 155.0
HKD1_k127_4022755_35 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000273 156.0
HKD1_k127_4022755_36 methylamine metabolic process K03885,K15977 - 1.6.99.3 0.00000000000000000000000000000000002716 139.0
HKD1_k127_4022755_37 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0044281,GO:0071704 2.3.1.101 0.0000000000000000000000000000000002241 134.0
HKD1_k127_4022755_38 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000008341 126.0
HKD1_k127_4022755_39 lipolytic protein G-D-S-L family - - - 0.00000000000000000000001018 113.0
HKD1_k127_4022755_4 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 528.0
HKD1_k127_4022755_40 receptor K16092 - - 0.00000000000000000000001043 117.0
HKD1_k127_4022755_41 - K01633,K07144 - 1.13.11.81,2.7.4.31,4.1.2.25,5.1.99.8 0.00000000000000000000007123 114.0
HKD1_k127_4022755_42 4-HFC-P synthase - - - 0.000000000000002508 85.0
HKD1_k127_4022755_43 - - - - 0.000000000000003558 78.0
HKD1_k127_4022755_45 nuclear chromosome segregation - - - 0.00007601 50.0
HKD1_k127_4022755_46 - - - - 0.0002034 52.0
HKD1_k127_4022755_5 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 473.0
HKD1_k127_4022755_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 471.0
HKD1_k127_4022755_7 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 415.0
HKD1_k127_4022755_8 Cytochrome c K08685 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 419.0
HKD1_k127_4022755_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 430.0
HKD1_k127_4029305_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016614,GO:0030151,GO:0033719,GO:0043167,GO:0043169,GO:0043546,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0097159,GO:1901363 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 290.0
HKD1_k127_4029305_1 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000002866 131.0
HKD1_k127_4029305_2 - - - - 0.00001032 50.0
HKD1_k127_4038063_0 Carboxypeptidase regulatory-like domain - - - 0.0 1315.0
HKD1_k127_4038063_1 AcrB/AcrD/AcrF family K15726 - - 0.0 1045.0
HKD1_k127_4038063_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000002432 185.0
HKD1_k127_4038063_11 - - - - 0.00000000000000000000000000000000000001309 160.0
HKD1_k127_4038063_12 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000001373 161.0
HKD1_k127_4038063_13 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000002419 154.0
HKD1_k127_4038063_14 Multicopper - - - 0.0000000000000000000000000000000001914 144.0
HKD1_k127_4038063_15 Cytochrome c - - - 0.0000000000000000000000000003986 123.0
HKD1_k127_4038063_16 Outer membrane efflux protein K15725 - - 0.0000000000000005976 91.0
HKD1_k127_4038063_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008757 378.0
HKD1_k127_4038063_3 PFAM multicopper oxidase type K08100,K14588 - 1.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 306.0
HKD1_k127_4038063_4 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007205 254.0
HKD1_k127_4038063_5 Transcriptional regulatory protein, C terminal K07669,K07672 - - 0.00000000000000000000000000000000000000000000000000000000000000000065 235.0
HKD1_k127_4038063_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004495 227.0
HKD1_k127_4038063_7 Member of a two-component regulatory system K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000007995 198.0
HKD1_k127_4038063_8 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000002183 185.0
HKD1_k127_4038063_9 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000002305 177.0
HKD1_k127_4039746_0 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 571.0
HKD1_k127_4039746_1 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000001967 246.0
HKD1_k127_4039746_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000009958 225.0
HKD1_k127_4040083_0 transmembrane transporter activity K03296,K07788,K07789 - - 3.087e-314 986.0
HKD1_k127_4040083_1 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 372.0
HKD1_k127_4040083_2 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 295.0
HKD1_k127_404573_0 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 516.0
HKD1_k127_404573_1 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 473.0
HKD1_k127_404573_10 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004213 286.0
HKD1_k127_404573_11 - K06862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002256 256.0
HKD1_k127_404573_12 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002889 216.0
HKD1_k127_404573_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000003151 188.0
HKD1_k127_404573_14 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000000000000000004986 188.0
HKD1_k127_404573_15 carboxylate-amine ligase domain protein - - - 0.0000000000000000000000000000000000000000000000005627 179.0
HKD1_k127_404573_16 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000002489 162.0
HKD1_k127_404573_17 protein import - - - 0.000000000000000000000000000000000000000004783 175.0
HKD1_k127_404573_18 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000244 162.0
HKD1_k127_404573_19 Transcriptional regulator - - - 0.0000000000000000000000000000000000000003893 161.0
HKD1_k127_404573_2 Major facilitator Superfamily K08178 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 460.0
HKD1_k127_404573_20 Domain of unknown function (DUF1956) - - - 0.00000000000000000000000000000000007343 141.0
HKD1_k127_404573_21 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000002593 117.0
HKD1_k127_404573_22 Redoxin K03386 - 1.11.1.15 0.00000000000000000000001332 108.0
HKD1_k127_404573_23 - - - - 0.00000000000000000002547 98.0
HKD1_k127_404573_24 DinB superfamily - - - 0.0000000000000000001462 95.0
HKD1_k127_404573_25 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000805 91.0
HKD1_k127_404573_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 472.0
HKD1_k127_404573_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 402.0
HKD1_k127_404573_5 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 409.0
HKD1_k127_404573_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 341.0
HKD1_k127_404573_7 Glycosyl transferase 4-like domain K03842 GO:0000003,GO:0003006,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009856,GO:0009987,GO:0010483,GO:0012505,GO:0019538,GO:0022414,GO:0032501,GO:0032502,GO:0034645,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044706,GO:0048856,GO:0048868,GO:0051703,GO:0051704,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.142 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 308.0
HKD1_k127_404573_8 MFS_1 like family K08151,K08153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 298.0
HKD1_k127_404573_9 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005421 299.0
HKD1_k127_4052641_0 Tricorn protease PDZ domain K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 539.0
HKD1_k127_4052641_1 von Willebrand factor, type A K07114 - - 0.0000000000000000006668 95.0
HKD1_k127_4070098_0 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 572.0
HKD1_k127_4070098_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 494.0
HKD1_k127_4070098_10 lactoylglutathione lyase activity K01759,K05606,K08234 - 4.4.1.5,5.1.99.1 0.000000000000000000000000002089 127.0
HKD1_k127_4070098_11 Methyltransferase - - - 0.000000001655 72.0
HKD1_k127_4070098_12 - - - - 0.0000005679 63.0
HKD1_k127_4070098_2 Glycosyl transferase, family 2 K01002,K20534 - 2.7.8.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 387.0
HKD1_k127_4070098_3 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 314.0
HKD1_k127_4070098_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001763 267.0
HKD1_k127_4070098_5 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000000000000000000000000000000000000000000004589 214.0
HKD1_k127_4070098_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000005775 190.0
HKD1_k127_4070098_7 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.000000000000000000000000000000000000001068 170.0
HKD1_k127_4070098_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000277 138.0
HKD1_k127_4070098_9 - - - - 0.0000000000000000000000000000002836 133.0
HKD1_k127_4074724_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 325.0
HKD1_k127_4074724_1 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 321.0
HKD1_k127_4074724_2 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000001926 249.0
HKD1_k127_4074724_3 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000001123 233.0
HKD1_k127_4074724_4 Transcriptional regulatory protein, C terminal K07659 - - 0.00000000000000000000000000000000000000000000000000000000000001209 222.0
HKD1_k127_4074724_5 - - - - 0.0000000000000000000000000000000000000000000000000006727 199.0
HKD1_k127_4074724_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000001322 177.0
HKD1_k127_4074724_7 NMT1-like family - - - 0.000000000000000000000000000001035 135.0
HKD1_k127_4074724_9 Cupin 2, conserved barrel domain protein - - - 0.0004146 52.0
HKD1_k127_4079036_0 Evidence 2b Function of strongly homologous gene K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 303.0
HKD1_k127_4079036_1 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000007902 222.0
HKD1_k127_4079036_2 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000002619 149.0
HKD1_k127_408387_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 1.734e-306 957.0
HKD1_k127_408387_1 PFAM aldo keto reductase K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 517.0
HKD1_k127_408387_10 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000001416 173.0
HKD1_k127_408387_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000003753 159.0
HKD1_k127_408387_12 - - - - 0.00000000000000000000000000000000001345 148.0
HKD1_k127_408387_13 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.00000000000000000000000000000000008934 147.0
HKD1_k127_408387_14 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000009059 136.0
HKD1_k127_408387_15 Cyclic nucleotide-monophosphate binding domain K09766 - - 0.00000000000000000000000000000003725 140.0
HKD1_k127_408387_16 - - - - 0.0000000000000000000000000000003189 127.0
HKD1_k127_408387_17 - - - - 0.0000000000000000003064 100.0
HKD1_k127_408387_18 - - - - 0.0000000000000005187 82.0
HKD1_k127_408387_19 - - - - 0.000000002863 65.0
HKD1_k127_408387_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 498.0
HKD1_k127_408387_20 - - - - 0.0000001014 60.0
HKD1_k127_408387_3 nitrite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 343.0
HKD1_k127_408387_4 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004511 301.0
HKD1_k127_408387_5 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 299.0
HKD1_k127_408387_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000525 261.0
HKD1_k127_408387_7 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001572 266.0
HKD1_k127_408387_8 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000000000000000000000000000000000000000000000000000006333 241.0
HKD1_k127_408387_9 HPP family - - - 0.0000000000000000000000000000000000000000000000000000000008417 208.0
HKD1_k127_4108_0 PA domain - - - 2.994e-221 696.0
HKD1_k127_4108_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 497.0
HKD1_k127_4114063_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 380.0
HKD1_k127_4114063_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 383.0
HKD1_k127_4114063_2 - - - - 0.0000000000000000000000000000000000000000000000000000000002351 231.0
HKD1_k127_4114063_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000009613 189.0
HKD1_k127_4114063_4 - - - - 0.0000007067 62.0
HKD1_k127_4117783_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 466.0
HKD1_k127_4117783_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000004356 158.0
HKD1_k127_4124518_0 PFAM asparagine synthase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002708 282.0
HKD1_k127_4124518_1 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000054 158.0
HKD1_k127_4124518_2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000006803 55.0
HKD1_k127_4146027_0 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 455.0
HKD1_k127_4146027_1 PFAM Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 432.0
HKD1_k127_4146027_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000008325 214.0
HKD1_k127_4146027_3 - - - - 0.0000000000000000000000000000000000007883 153.0
HKD1_k127_4146027_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000003376 128.0
HKD1_k127_4174135_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.354e-271 859.0
HKD1_k127_4174135_1 Spermine/spermidine synthase domain - - - 1.39e-251 799.0
HKD1_k127_4174135_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K16049 - 1.13.11.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 452.0
HKD1_k127_4174135_11 ankyrin repeat K15503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 477.0
HKD1_k127_4174135_12 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 449.0
HKD1_k127_4174135_13 tRNA wobble cytosine modification - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 439.0
HKD1_k127_4174135_14 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 422.0
HKD1_k127_4174135_15 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 419.0
HKD1_k127_4174135_16 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836 411.0
HKD1_k127_4174135_17 Amidohydrolase K10220 - 4.2.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 397.0
HKD1_k127_4174135_18 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 381.0
HKD1_k127_4174135_19 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 377.0
HKD1_k127_4174135_2 Glucose / Sorbosone dehydrogenase - - - 2.49e-217 698.0
HKD1_k127_4174135_20 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 386.0
HKD1_k127_4174135_21 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 361.0
HKD1_k127_4174135_22 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 370.0
HKD1_k127_4174135_23 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 340.0
HKD1_k127_4174135_24 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 336.0
HKD1_k127_4174135_25 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 326.0
HKD1_k127_4174135_26 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 298.0
HKD1_k127_4174135_27 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 295.0
HKD1_k127_4174135_28 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000242 314.0
HKD1_k127_4174135_29 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003374 287.0
HKD1_k127_4174135_3 DNA topological change K03168 - 5.99.1.2 1.79e-211 709.0
HKD1_k127_4174135_30 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001211 300.0
HKD1_k127_4174135_31 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001209 293.0
HKD1_k127_4174135_32 SPFH Band 7 PHB domain protein - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000001331 261.0
HKD1_k127_4174135_33 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000009822 246.0
HKD1_k127_4174135_34 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000004009 235.0
HKD1_k127_4174135_35 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000707 235.0
HKD1_k127_4174135_36 transcriptional regulator K09017 - - 0.00000000000000000000000000000000000000000000000000000000000002088 222.0
HKD1_k127_4174135_37 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000006027 218.0
HKD1_k127_4174135_38 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000004641 212.0
HKD1_k127_4174135_39 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000009144 206.0
HKD1_k127_4174135_4 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 517.0
HKD1_k127_4174135_40 COG0714 MoxR-like ATPases K03924 - - 0.00000000000000000000000000000000000000000000000000672 195.0
HKD1_k127_4174135_41 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000001074 190.0
HKD1_k127_4174135_42 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000009293 174.0
HKD1_k127_4174135_43 Belongs to the UPF0311 family - - - 0.0000000000000000000000000000000000000002787 154.0
HKD1_k127_4174135_44 - - - - 0.00000000000000000000000000000000000004594 154.0
HKD1_k127_4174135_46 Transcription factor zinc-finger - - - 0.00000000000000000000000000000001936 132.0
HKD1_k127_4174135_47 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000005327 130.0
HKD1_k127_4174135_48 signal sequence binding K07152 - - 0.000000000000000000000000006593 111.0
HKD1_k127_4174135_49 FMN_bind K19339 - - 0.00000000000000000000000002787 125.0
HKD1_k127_4174135_5 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 541.0
HKD1_k127_4174135_50 Tetratricopeptide repeat - - - 0.00000000000000000000000003097 118.0
HKD1_k127_4174135_51 - - - - 0.000000000000000000000009048 102.0
HKD1_k127_4174135_52 solute binding protein K02035 - - 0.00000000000000000004171 103.0
HKD1_k127_4174135_53 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.000000000000000002238 87.0
HKD1_k127_4174135_54 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000003054 89.0
HKD1_k127_4174135_55 Radical SAM domain protein K06871 - - 0.000000000000001317 90.0
HKD1_k127_4174135_56 Bacterial regulatory proteins, tetR family - GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000005729 83.0
HKD1_k127_4174135_57 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000586 88.0
HKD1_k127_4174135_58 IgA Peptidase M64 - - - 0.00000000000007576 85.0
HKD1_k127_4174135_59 FMN_bind - - - 0.00000000000136 76.0
HKD1_k127_4174135_6 PFAM peptidase U62 modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 533.0
HKD1_k127_4174135_60 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000955 70.0
HKD1_k127_4174135_61 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.000000002478 65.0
HKD1_k127_4174135_62 histidine kinase A domain protein - - - 0.000000002714 66.0
HKD1_k127_4174135_63 oxidoreductase activity K07114 - - 0.0000000285 67.0
HKD1_k127_4174135_64 PFAM PEGA domain - - - 0.0000001032 65.0
HKD1_k127_4174135_65 PFAM von Willebrand factor type A K07114 - - 0.000000146 63.0
HKD1_k127_4174135_66 protein conserved in bacteria K15539 - - 0.0000005351 61.0
HKD1_k127_4174135_67 response regulator K07712 - - 0.000000536 60.0
HKD1_k127_4174135_68 cellulose binding - - - 0.000008462 57.0
HKD1_k127_4174135_69 NMT1-like family K02051,K15551 - - 0.0001731 53.0
HKD1_k127_4174135_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 481.0
HKD1_k127_4174135_70 - - - - 0.0002086 51.0
HKD1_k127_4174135_71 TonB-dependent Receptor Plug Domain - - - 0.0003338 52.0
HKD1_k127_4174135_8 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 509.0
HKD1_k127_4174135_9 Sugar (and other) transporter K08195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 474.0
HKD1_k127_4214011_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.69e-232 728.0
HKD1_k127_4214011_1 HipA domain protein K07154 - 2.7.11.1 1.495e-195 617.0
HKD1_k127_4214011_10 heme binding - - - 0.0000000000000000000000000000000000000000000000000004948 201.0
HKD1_k127_4214011_11 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000005723 206.0
HKD1_k127_4214011_12 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000004732 176.0
HKD1_k127_4214011_13 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000006932 180.0
HKD1_k127_4214011_14 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000004647 170.0
HKD1_k127_4214011_15 Type II secretory pathway component ExeA K02450 - - 0.000000000000000000000000000000000000000000889 174.0
HKD1_k127_4214011_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000001325 159.0
HKD1_k127_4214011_17 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000182 153.0
HKD1_k127_4214011_18 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000003211 126.0
HKD1_k127_4214011_19 PFAM von Willebrand factor type A K07114,K12511 - - 0.000000000000000000000000000001382 136.0
HKD1_k127_4214011_2 Peptidase family S41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 567.0
HKD1_k127_4214011_20 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000949 122.0
HKD1_k127_4214011_21 sequence-specific DNA binding - - - 0.0000000000000000000000000001504 118.0
HKD1_k127_4214011_22 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000004 133.0
HKD1_k127_4214011_23 - - - - 0.000000000000000000000004476 116.0
HKD1_k127_4214011_24 - - - - 0.00000000000000000000001818 112.0
HKD1_k127_4214011_25 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000176 99.0
HKD1_k127_4214011_26 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000003248 83.0
HKD1_k127_4214011_27 - - - - 0.00000000000001792 78.0
HKD1_k127_4214011_28 - - - - 0.00000000002425 78.0
HKD1_k127_4214011_29 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000004627 72.0
HKD1_k127_4214011_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 430.0
HKD1_k127_4214011_30 Outer membrane protein beta-barrel domain - - - 0.00000000007252 72.0
HKD1_k127_4214011_32 oxidoreductase activity - - - 0.000000004673 71.0
HKD1_k127_4214011_33 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.000002621 57.0
HKD1_k127_4214011_34 general secretion pathway protein - - - 0.000005658 49.0
HKD1_k127_4214011_35 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00004087 58.0
HKD1_k127_4214011_4 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 430.0
HKD1_k127_4214011_5 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009159 416.0
HKD1_k127_4214011_6 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 398.0
HKD1_k127_4214011_7 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 338.0
HKD1_k127_4214011_8 gluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002084 258.0
HKD1_k127_4214011_9 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000004079 211.0
HKD1_k127_4215512_0 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000000000000000000000000000001074 240.0
HKD1_k127_4215512_1 Lanthionine synthetase C-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002707 226.0
HKD1_k127_4215512_2 Chloramphenicol phosphotransferase-like protein K18554 - - 0.000000000000000000000000000000000000000000000000000000594 206.0
HKD1_k127_4243439_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.208e-292 918.0
HKD1_k127_4243439_1 carbamoyl transferase, NodU family K00612 - - 7.038e-195 632.0
HKD1_k127_4243439_10 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000009451 226.0
HKD1_k127_4243439_11 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000006076 241.0
HKD1_k127_4243439_12 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000008752 228.0
HKD1_k127_4243439_13 - - - - 0.0000000000000000000000000000000000000000000000000000000001233 222.0
HKD1_k127_4243439_14 Glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000001162 225.0
HKD1_k127_4243439_15 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000001601 206.0
HKD1_k127_4243439_16 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000001003 196.0
HKD1_k127_4243439_17 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000003638 179.0
HKD1_k127_4243439_18 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000003912 182.0
HKD1_k127_4243439_19 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000004465 166.0
HKD1_k127_4243439_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 549.0
HKD1_k127_4243439_20 methyltransferase - - - 0.0000000000000000000000000000000000000003202 169.0
HKD1_k127_4243439_21 export protein K01991 - - 0.000000000000000000000000000000000000001445 160.0
HKD1_k127_4243439_22 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000241 162.0
HKD1_k127_4243439_23 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000001509 136.0
HKD1_k127_4243439_24 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.00000000000000000000000000000001521 140.0
HKD1_k127_4243439_25 Ferrous iron transport protein B K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000001553 118.0
HKD1_k127_4243439_26 Glycosyl transferases group 1 - - - 0.00000000000000000000000001622 126.0
HKD1_k127_4243439_27 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000585 112.0
HKD1_k127_4243439_28 PFAM Methyltransferase type 11 - - - 0.0000000000000000000006543 109.0
HKD1_k127_4243439_29 N-acetyl-alpha-D-glucosaminyl L-malate synthase K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000007622 80.0
HKD1_k127_4243439_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 435.0
HKD1_k127_4243439_30 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000001363 76.0
HKD1_k127_4243439_31 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000004482 72.0
HKD1_k127_4243439_32 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001169 55.0
HKD1_k127_4243439_4 asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 370.0
HKD1_k127_4243439_5 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 319.0
HKD1_k127_4243439_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 297.0
HKD1_k127_4243439_7 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001969 263.0
HKD1_k127_4243439_8 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000001014 254.0
HKD1_k127_4243439_9 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002019 252.0
HKD1_k127_426498_0 TonB-dependent receptor - - - 0.0 1509.0
HKD1_k127_426498_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 2.346e-249 790.0
HKD1_k127_426498_10 Beta-eliminating lyase K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 361.0
HKD1_k127_426498_11 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 313.0
HKD1_k127_426498_12 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 292.0
HKD1_k127_426498_13 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009261 285.0
HKD1_k127_426498_14 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005365 272.0
HKD1_k127_426498_15 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003736 256.0
HKD1_k127_426498_16 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000008892 266.0
HKD1_k127_426498_17 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003611 239.0
HKD1_k127_426498_18 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000002722 238.0
HKD1_k127_426498_19 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000002464 232.0
HKD1_k127_426498_2 Phosphate acyltransferases K01897 - 6.2.1.3 4.277e-239 768.0
HKD1_k127_426498_20 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000142 223.0
HKD1_k127_426498_21 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000001975 217.0
HKD1_k127_426498_22 Belongs to the enoyl-CoA hydratase isomerase family K15313 - - 0.000000000000000000000000000000000000000000000000000000005573 213.0
HKD1_k127_426498_23 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000001055 199.0
HKD1_k127_426498_24 HDOD domain K03088 - - 0.00000000000000000000000000000000000000000000008597 173.0
HKD1_k127_426498_25 RDD family - - - 0.0000000000000000000000000000000000000000000005592 187.0
HKD1_k127_426498_26 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000008328 175.0
HKD1_k127_426498_27 protein methyltransferase activity - - - 0.00000000000000000000000000000000000000000007392 172.0
HKD1_k127_426498_28 P63C domain - - - 0.0000000000000000000000000000000000000000003382 162.0
HKD1_k127_426498_29 FabA-like domain K02372 - 4.2.1.59 0.000000000000000000000000000000000000000008661 160.0
HKD1_k127_426498_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 535.0
HKD1_k127_426498_30 Enoyl-CoA hydratase/isomerase K15312 - - 0.000000000000000000000000002888 123.0
HKD1_k127_426498_31 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000003094 110.0
HKD1_k127_426498_32 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000005303 103.0
HKD1_k127_426498_33 O-linked GlcNAc transferase - - - 0.0000000000000000000002698 109.0
HKD1_k127_426498_34 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000009082 108.0
HKD1_k127_426498_35 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000002984 92.0
HKD1_k127_426498_36 Protein of unknown function (DUF3108) - - - 0.00000000001431 76.0
HKD1_k127_426498_38 - - - - 0.0000005423 62.0
HKD1_k127_426498_4 Belongs to the beta-ketoacyl-ACP synthases family K00646 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 512.0
HKD1_k127_426498_5 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 472.0
HKD1_k127_426498_6 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 445.0
HKD1_k127_426498_7 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 412.0
HKD1_k127_426498_8 synthase K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 405.0
HKD1_k127_426498_9 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 356.0
HKD1_k127_4281814_0 domain protein - - - 0.0 1095.0
HKD1_k127_4281814_1 Carboxypeptidase regulatory-like domain - - - 2.365e-289 919.0
HKD1_k127_4281814_10 Phage tail sheath C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 510.0
HKD1_k127_4281814_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 478.0
HKD1_k127_4281814_12 Pyrrolo-quinoline quinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 496.0
HKD1_k127_4281814_13 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K18219,K20919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 469.0
HKD1_k127_4281814_14 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 455.0
HKD1_k127_4281814_15 Tail protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 442.0
HKD1_k127_4281814_16 PFAM Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 425.0
HKD1_k127_4281814_17 Protein of unknown function (DUF3738) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006633 433.0
HKD1_k127_4281814_18 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 379.0
HKD1_k127_4281814_19 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 376.0
HKD1_k127_4281814_2 Phage tail protein (Tail_P2_I) - - - 1.908e-282 906.0
HKD1_k127_4281814_20 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 353.0
HKD1_k127_4281814_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 365.0
HKD1_k127_4281814_24 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009473 352.0
HKD1_k127_4281814_25 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 349.0
HKD1_k127_4281814_26 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 351.0
HKD1_k127_4281814_27 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 314.0
HKD1_k127_4281814_28 Rhs Element Vgr Protein K11904 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 299.0
HKD1_k127_4281814_29 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 321.0
HKD1_k127_4281814_3 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 2.307e-274 863.0
HKD1_k127_4281814_30 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005406 295.0
HKD1_k127_4281814_31 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002496 295.0
HKD1_k127_4281814_32 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001493 276.0
HKD1_k127_4281814_34 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001221 262.0
HKD1_k127_4281814_35 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001636 240.0
HKD1_k127_4281814_36 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000000000000000000000000000005421 232.0
HKD1_k127_4281814_37 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000003259 226.0
HKD1_k127_4281814_38 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000003078 234.0
HKD1_k127_4281814_39 (2Fe-2S) binding domain protein K07302,K18029 - 1.17.2.1,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000009255 220.0
HKD1_k127_4281814_4 tail sheath protein K06907 - - 1.065e-242 759.0
HKD1_k127_4281814_40 PAAR motif - - - 0.0000000000000000000000000000000000000000000000000000000000003163 214.0
HKD1_k127_4281814_41 GPW gp25 family protein K06903 - - 0.000000000000000000000000000000000000000000000000000000000001931 213.0
HKD1_k127_4281814_42 ankyrin repeat K15503 - - 0.000000000000000000000000000000000000000000000000000000000008952 229.0
HKD1_k127_4281814_43 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000003331 205.0
HKD1_k127_4281814_44 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000000000000000000001034 188.0
HKD1_k127_4281814_45 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000258 175.0
HKD1_k127_4281814_46 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000004598 159.0
HKD1_k127_4281814_47 Protein of unknown function (DUF1109) - - - 0.00000000000000000000000000000000000000001244 162.0
HKD1_k127_4281814_48 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000622 161.0
HKD1_k127_4281814_49 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000005271 150.0
HKD1_k127_4281814_5 Baseplate J-like protein - - - 7.905e-240 757.0
HKD1_k127_4281814_50 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000002339 157.0
HKD1_k127_4281814_51 - - - - 0.000000000000000000000000000000236 140.0
HKD1_k127_4281814_53 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000003041 109.0
HKD1_k127_4281814_55 - - - - 0.00000000000000000001976 106.0
HKD1_k127_4281814_56 - - - - 0.00000000000000000003299 102.0
HKD1_k127_4281814_58 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000007756 86.0
HKD1_k127_4281814_6 DNA topological change K03168 - 5.99.1.2 5.19e-205 664.0
HKD1_k127_4281814_60 - - - - 0.0000000000005776 74.0
HKD1_k127_4281814_61 TadE-like protein - - - 0.000000000002032 75.0
HKD1_k127_4281814_62 DNA topological change - - - 0.000000000002485 68.0
HKD1_k127_4281814_63 Lipocalin-like domain - - - 0.000000008005 67.0
HKD1_k127_4281814_64 Metallo-beta-lactamase superfamily - - - 0.00000004782 64.0
HKD1_k127_4281814_65 Lipocalin-like domain - - - 0.000001359 60.0
HKD1_k127_4281814_66 Cytochrome c K08738 - - 0.00001615 58.0
HKD1_k127_4281814_67 Metallo-beta-lactamase superfamily - - - 0.000108 55.0
HKD1_k127_4281814_7 Late control gene D protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 571.0
HKD1_k127_4281814_8 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 522.0
HKD1_k127_4281814_9 alcohol dehydrogenase K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 521.0
HKD1_k127_4299562_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.804e-313 980.0
HKD1_k127_4299562_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 6.844e-290 937.0
HKD1_k127_4299562_10 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 516.0
HKD1_k127_4299562_11 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 505.0
HKD1_k127_4299562_12 Nucleotidyl transferase K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 450.0
HKD1_k127_4299562_13 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 444.0
HKD1_k127_4299562_14 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 390.0
HKD1_k127_4299562_15 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 378.0
HKD1_k127_4299562_16 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 365.0
HKD1_k127_4299562_17 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 306.0
HKD1_k127_4299562_18 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 308.0
HKD1_k127_4299562_19 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 303.0
HKD1_k127_4299562_2 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 5.667e-282 877.0
HKD1_k127_4299562_20 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004212 279.0
HKD1_k127_4299562_21 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009722 259.0
HKD1_k127_4299562_22 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007294 249.0
HKD1_k127_4299562_23 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000003962 244.0
HKD1_k127_4299562_24 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000004551 180.0
HKD1_k127_4299562_25 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000001803 160.0
HKD1_k127_4299562_26 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000005175 144.0
HKD1_k127_4299562_27 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000001447 119.0
HKD1_k127_4299562_28 Transcription termination factor nusG - - - 0.000000000000000000000000008487 126.0
HKD1_k127_4299562_29 Regulatory protein, FmdB - - - 0.00000000000000000000002916 104.0
HKD1_k127_4299562_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.181e-279 886.0
HKD1_k127_4299562_30 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000001884 98.0
HKD1_k127_4299562_31 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000006657 99.0
HKD1_k127_4299562_32 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000002258 100.0
HKD1_k127_4299562_33 R3H domain protein K06346 - - 0.00000000000000001568 97.0
HKD1_k127_4299562_34 PFAM VanZ like family - - - 0.000000000000001286 81.0
HKD1_k127_4299562_35 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000001825 84.0
HKD1_k127_4299562_36 Ribonuclease P K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.00000000000006116 76.0
HKD1_k127_4299562_37 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001597 72.0
HKD1_k127_4299562_4 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.06e-249 792.0
HKD1_k127_4299562_5 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 1.224e-241 754.0
HKD1_k127_4299562_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.212e-233 741.0
HKD1_k127_4299562_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.487e-224 704.0
HKD1_k127_4299562_8 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 7.831e-203 649.0
HKD1_k127_4299562_9 PFAM UvrD REP helicase K03657 - 3.6.4.12 9.577e-197 638.0
HKD1_k127_43183_0 Cytochrome c - - - 3.615e-197 621.0
HKD1_k127_43183_1 Formylmethanofuran dehydrogenase subunit A K00200 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 589.0
HKD1_k127_43183_10 Methylene-tetrahydromethanopterin dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001053 262.0
HKD1_k127_43183_11 formaldehyde-activating enzyme K10713 - 4.2.1.147 0.00000000000000000000000000000000000000000000000000000000000000000000002229 245.0
HKD1_k127_43183_12 CO2 hydration protein (ChpXY) - - - 0.0000000000000000000000000000000000000000000000000000000001001 219.0
HKD1_k127_43183_13 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000004665 213.0
HKD1_k127_43183_14 ATP-grasp domain K01499,K06913 - 3.5.4.27 0.0000000000000000000000000000000000000000000000000000000059 213.0
HKD1_k127_43183_15 formylmethanofuran dehydrogenase, subunit K00201 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000001597 208.0
HKD1_k127_43183_16 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000000002336 163.0
HKD1_k127_43183_17 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000006382 141.0
HKD1_k127_43183_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000105 66.0
HKD1_k127_43183_2 Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 487.0
HKD1_k127_43183_20 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00001482 56.0
HKD1_k127_43183_3 with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 347.0
HKD1_k127_43183_4 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 326.0
HKD1_k127_43183_5 2-keto-4-pentenoate hydratase K02554 - 4.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 314.0
HKD1_k127_43183_6 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 293.0
HKD1_k127_43183_7 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002238 289.0
HKD1_k127_43183_8 Formylmethanofuran-tetrahydromethanopterin formyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009168 265.0
HKD1_k127_43183_9 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000003002 259.0
HKD1_k127_4330385_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 438.0
HKD1_k127_4330385_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000003128 228.0
HKD1_k127_4330385_2 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000002218 205.0
HKD1_k127_4342225_0 ABC transporter K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 1.766e-285 898.0
HKD1_k127_4342225_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 1.34e-258 821.0
HKD1_k127_4342225_10 phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006944 274.0
HKD1_k127_4342225_11 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001349 264.0
HKD1_k127_4342225_12 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000001644 239.0
HKD1_k127_4342225_13 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000003687 208.0
HKD1_k127_4342225_14 COG0491 Zn-dependent hydrolases, including glyoxylases K13075 - 3.1.1.81 0.000000000000000000000000000000000000000000000000000148 196.0
HKD1_k127_4342225_15 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000191 201.0
HKD1_k127_4342225_16 PFAM SMP-30 Gluconolaconase K08685 - 1.4.9.1 0.0000000000000000000000000000000000009665 160.0
HKD1_k127_4342225_17 CBS domain - - - 0.00000000000000000000000000000000002615 143.0
HKD1_k127_4342225_18 Class I peptide chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000000153 134.0
HKD1_k127_4342225_19 SMART Extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000006467 105.0
HKD1_k127_4342225_2 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 2.435e-228 720.0
HKD1_k127_4342225_20 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000003581 93.0
HKD1_k127_4342225_21 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000006412 89.0
HKD1_k127_4342225_22 helix_turn_helix, Lux Regulon - - - 0.000000000000008553 87.0
HKD1_k127_4342225_23 Belongs to the glycosyl hydrolase 13 family K01176 - 3.2.1.1 0.000000001333 69.0
HKD1_k127_4342225_24 - - - - 0.000002195 59.0
HKD1_k127_4342225_26 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.0008829 51.0
HKD1_k127_4342225_3 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 532.0
HKD1_k127_4342225_4 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 459.0
HKD1_k127_4342225_5 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 452.0
HKD1_k127_4342225_6 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 413.0
HKD1_k127_4342225_7 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 340.0
HKD1_k127_4342225_8 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 340.0
HKD1_k127_4342225_9 G8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 295.0
HKD1_k127_4345674_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 324.0
HKD1_k127_4345674_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 328.0
HKD1_k127_4345674_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 309.0
HKD1_k127_4345674_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000047 197.0
HKD1_k127_4348045_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.305e-249 792.0
HKD1_k127_4348045_1 oligopeptide transporter, OPT family - - - 4.463e-196 632.0
HKD1_k127_4348045_10 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000003058 192.0
HKD1_k127_4348045_11 HD domain - - - 0.000000000000000000000000000000000000000000000006674 196.0
HKD1_k127_4348045_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K00338 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000004727 173.0
HKD1_k127_4348045_13 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000007654 171.0
HKD1_k127_4348045_14 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000003336 173.0
HKD1_k127_4348045_15 geranylgeranyl reductase activity K21401 - 1.3.99.38 0.000000000000000000000000000000000000002265 161.0
HKD1_k127_4348045_16 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000004087 154.0
HKD1_k127_4348045_17 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000002119 153.0
HKD1_k127_4348045_18 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000007814 130.0
HKD1_k127_4348045_19 NnrU protein K21310 - 2.1.1.334 0.00000000000000000000000000004547 125.0
HKD1_k127_4348045_2 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 413.0
HKD1_k127_4348045_20 Mannosyltransferase (PIG-V) - - - 0.000000000000000000000000002014 127.0
HKD1_k127_4348045_21 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.000000000000000000000001209 113.0
HKD1_k127_4348045_22 phosphoesterases, related to the Icc protein - - - 0.000000000000000000000002266 115.0
HKD1_k127_4348045_23 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000005 96.0
HKD1_k127_4348045_3 Histidine kinase K02478 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 338.0
HKD1_k127_4348045_4 PFAM ATPase associated with various cellular activities AAA_3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 323.0
HKD1_k127_4348045_5 PFAM Glutamine cyclotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 314.0
HKD1_k127_4348045_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 332.0
HKD1_k127_4348045_7 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001024 253.0
HKD1_k127_4348045_8 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000546 231.0
HKD1_k127_4348045_9 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000002297 201.0
HKD1_k127_4359855_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1117.0
HKD1_k127_4359855_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 6.834e-307 960.0
HKD1_k127_4359855_10 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 369.0
HKD1_k127_4359855_11 glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 351.0
HKD1_k127_4359855_12 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 305.0
HKD1_k127_4359855_13 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000239 284.0
HKD1_k127_4359855_15 Ferric uptake regulator family K22297 - - 0.000000000000000000000000000000000000000000000000000000002166 202.0
HKD1_k127_4359855_16 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.000000000000000000000000000000000000000000000000006591 198.0
HKD1_k127_4359855_17 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000003922 183.0
HKD1_k127_4359855_18 alpha beta - - - 0.00000000000000000000000000000000000000000003845 179.0
HKD1_k127_4359855_19 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000004271 165.0
HKD1_k127_4359855_2 Glucose / Sorbosone dehydrogenase - - - 1.152e-225 703.0
HKD1_k127_4359855_20 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000007945 158.0
HKD1_k127_4359855_21 - - - - 0.00000000000000000000000000000000002032 152.0
HKD1_k127_4359855_22 Histidine kinase - - - 0.000000000000000000000009912 107.0
HKD1_k127_4359855_23 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000001147 107.0
HKD1_k127_4359855_24 ATPase (AAA K06923 - - 0.00000000000000000009444 90.0
HKD1_k127_4359855_26 Cold shock protein domain - - - 0.0000000000000000008601 92.0
HKD1_k127_4359855_27 endonuclease activity - - - 0.0000000000000001401 87.0
HKD1_k127_4359855_28 YjbR - - - 0.00000000001095 78.0
HKD1_k127_4359855_29 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0000000000233 76.0
HKD1_k127_4359855_3 PFAM Radical SAM - - - 1.788e-217 686.0
HKD1_k127_4359855_30 Protein of unknown function (DUF1566) - - - 0.000002671 59.0
HKD1_k127_4359855_31 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00003546 55.0
HKD1_k127_4359855_32 AraC-like ligand binding domain K18954 - - 0.0001453 53.0
HKD1_k127_4359855_33 Protein of unknown function (DUF2846) - - - 0.000275 53.0
HKD1_k127_4359855_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 601.0
HKD1_k127_4359855_5 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 573.0
HKD1_k127_4359855_6 Belongs to the OprB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 495.0
HKD1_k127_4359855_7 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 398.0
HKD1_k127_4359855_8 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 380.0
HKD1_k127_4359855_9 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000093 372.0
HKD1_k127_4384251_0 Phosphoenolpyruvate carboxykinase - - - 5.382e-291 904.0
HKD1_k127_4384251_1 GTP-binding protein TypA K06207 - - 1.751e-263 822.0
HKD1_k127_4384251_10 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 449.0
HKD1_k127_4384251_11 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 455.0
HKD1_k127_4384251_12 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 421.0
HKD1_k127_4384251_13 Threonine synthase N terminus K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 404.0
HKD1_k127_4384251_14 major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 381.0
HKD1_k127_4384251_15 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 375.0
HKD1_k127_4384251_16 Possible lysine decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 327.0
HKD1_k127_4384251_17 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 344.0
HKD1_k127_4384251_18 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000005635 271.0
HKD1_k127_4384251_19 Met-10+ like-protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004762 250.0
HKD1_k127_4384251_2 protein secretion by the type I secretion system K11085 - - 2.676e-246 777.0
HKD1_k127_4384251_20 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000005867 246.0
HKD1_k127_4384251_21 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000001598 243.0
HKD1_k127_4384251_22 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000001005 218.0
HKD1_k127_4384251_23 RNA pseudouridylate synthase K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000007066 209.0
HKD1_k127_4384251_24 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000008554 204.0
HKD1_k127_4384251_25 TraB family K09973 - - 0.0000000000000000000000000000000000000000000000000007589 195.0
HKD1_k127_4384251_26 UvrD/REP helicase N-terminal domain - - - 0.00000000000000000000000000000000000000000000003412 176.0
HKD1_k127_4384251_27 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.0000000000000000000000000000000000000000000002126 175.0
HKD1_k127_4384251_28 WYL domain K13572 - - 0.00000000000000000000000000000000000000000000165 178.0
HKD1_k127_4384251_29 ECF sigma factor - - - 0.000000000000000000000000000000000000000001866 165.0
HKD1_k127_4384251_3 PD-(D/E)XK nuclease superfamily - - - 5.955e-236 790.0
HKD1_k127_4384251_30 CoA-binding protein K06929 - - 0.000000000000000000000000000000000002298 157.0
HKD1_k127_4384251_31 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000003943 144.0
HKD1_k127_4384251_32 PFAM S23 ribosomal protein - - - 0.000000000000000000000000000001934 124.0
HKD1_k127_4384251_33 - - - - 0.0000000000000000000005528 110.0
HKD1_k127_4384251_34 Domain of unknown function (DUF4440) - - - 0.0000000000000007946 92.0
HKD1_k127_4384251_35 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000001948 77.0
HKD1_k127_4384251_36 fructose-bisphosphate aldolase, class II, yeast E. coli subtype K01624 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.1.2.13 0.000000000006149 73.0
HKD1_k127_4384251_37 Stress responsive A/B Barrel Domain - - - 0.00000000004435 72.0
HKD1_k127_4384251_38 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000008035 57.0
HKD1_k127_4384251_39 Phosphopantetheine attachment site - - - 0.0001427 48.0
HKD1_k127_4384251_4 Oligopeptidase F K08602 - - 7.264e-212 674.0
HKD1_k127_4384251_40 - - - - 0.0006033 49.0
HKD1_k127_4384251_5 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 1.874e-195 617.0
HKD1_k127_4384251_6 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 576.0
HKD1_k127_4384251_7 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 455.0
HKD1_k127_4384251_8 Aldo Keto reductase K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 466.0
HKD1_k127_4384251_9 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 436.0
HKD1_k127_4388437_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 572.0
HKD1_k127_4388437_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003704 268.0
HKD1_k127_4388437_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000008632 227.0
HKD1_k127_4388437_3 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000117 189.0
HKD1_k127_4388437_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000002912 183.0
HKD1_k127_4388437_5 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000009885 114.0
HKD1_k127_4397462_0 - - - - 2.949e-220 704.0
HKD1_k127_4397462_1 Alpha amylase, catalytic domain K00690,K05343 - 2.4.1.7,3.2.1.1,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 607.0
HKD1_k127_4397462_10 - - - - 0.0000002658 62.0
HKD1_k127_4397462_11 - - - - 0.000001024 59.0
HKD1_k127_4397462_2 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 567.0
HKD1_k127_4397462_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 500.0
HKD1_k127_4397462_4 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 495.0
HKD1_k127_4397462_5 Belongs to the glycosyl hydrolase 13 family K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 406.0
HKD1_k127_4397462_6 G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 374.0
HKD1_k127_4397462_7 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 310.0
HKD1_k127_4397462_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000009198 232.0
HKD1_k127_4397462_9 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000002282 130.0
HKD1_k127_4420539_0 Domain of Unknown Function (DUF1080) - - - 0.0 1497.0
HKD1_k127_4420539_1 Aminomethyltransferase folate-binding domain K15066 - 2.1.1.341 9.127e-234 730.0
HKD1_k127_4420539_10 Domain of unknown function (DUF4281) - - - 0.0000000000000000000000000000000000000000001511 163.0
HKD1_k127_4420539_11 ATPases associated with a variety of cellular activities K02017,K02018 - 3.6.3.29 0.0000000000000000000000000000000000000000084 164.0
HKD1_k127_4420539_12 - - - - 0.00000000000000000000000000000000000000369 158.0
HKD1_k127_4420539_13 WHG domain - - - 0.00000000000000000000000000000000007442 141.0
HKD1_k127_4420539_14 - - - - 0.0000000000000000000000001296 111.0
HKD1_k127_4420539_15 PQ loop repeat K15383 - - 0.0000000004139 72.0
HKD1_k127_4420539_17 - - - - 0.000001916 60.0
HKD1_k127_4420539_18 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000005303 59.0
HKD1_k127_4420539_2 Carboxypeptidase regulatory-like domain - - - 8.084e-217 704.0
HKD1_k127_4420539_3 Cytochrome D1 heme domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 499.0
HKD1_k127_4420539_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 383.0
HKD1_k127_4420539_5 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001592 285.0
HKD1_k127_4420539_6 Ankyrin repeats (many copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003174 288.0
HKD1_k127_4420539_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003299 234.0
HKD1_k127_4420539_8 Pyruvate phosphate dikinase - - - 0.0000000000000000000000000000000000000000000000000000000000000515 220.0
HKD1_k127_4420539_9 - - - - 0.0000000000000000000000000000000000000000000000000003005 195.0
HKD1_k127_4425502_0 PFAM Peptidase M16 K07263 - - 0.0 1035.0
HKD1_k127_4425502_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 1.419e-212 670.0
HKD1_k127_4425502_10 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 334.0
HKD1_k127_4425502_11 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 314.0
HKD1_k127_4425502_12 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000444 299.0
HKD1_k127_4425502_13 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002211 299.0
HKD1_k127_4425502_14 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001221 257.0
HKD1_k127_4425502_15 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000001411 233.0
HKD1_k127_4425502_16 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000001066 255.0
HKD1_k127_4425502_17 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000111 225.0
HKD1_k127_4425502_18 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000002141 231.0
HKD1_k127_4425502_19 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000002944 222.0
HKD1_k127_4425502_2 radical SAM domain protein - - - 6.021e-211 667.0
HKD1_k127_4425502_20 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000002167 193.0
HKD1_k127_4425502_21 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000005468 202.0
HKD1_k127_4425502_22 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000001163 193.0
HKD1_k127_4425502_23 - - - - 0.000000000000000000000000000000000000000000000002238 190.0
HKD1_k127_4425502_24 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000005559 156.0
HKD1_k127_4425502_25 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000006323 138.0
HKD1_k127_4425502_26 AhpC/TSA family - - - 0.000000000000000000000000001499 131.0
HKD1_k127_4425502_27 arsR family - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000003435 109.0
HKD1_k127_4425502_28 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX - - - 0.000000000000000000036 106.0
HKD1_k127_4425502_29 Methyltransferase - - - 0.000000000003127 77.0
HKD1_k127_4425502_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 8.048e-206 647.0
HKD1_k127_4425502_30 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000006833 62.0
HKD1_k127_4425502_4 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 423.0
HKD1_k127_4425502_5 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 416.0
HKD1_k127_4425502_6 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 384.0
HKD1_k127_4425502_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 389.0
HKD1_k127_4425502_8 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 392.0
HKD1_k127_4425502_9 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 345.0
HKD1_k127_4448759_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 344.0
HKD1_k127_4505964_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.02e-317 985.0
HKD1_k127_4505964_1 Spermine/spermidine synthase domain - - - 2.798e-262 831.0
HKD1_k127_4505964_10 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 405.0
HKD1_k127_4505964_11 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 398.0
HKD1_k127_4505964_12 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 403.0
HKD1_k127_4505964_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 327.0
HKD1_k127_4505964_14 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 337.0
HKD1_k127_4505964_15 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 323.0
HKD1_k127_4505964_16 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 322.0
HKD1_k127_4505964_17 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 289.0
HKD1_k127_4505964_18 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 288.0
HKD1_k127_4505964_19 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000008997 287.0
HKD1_k127_4505964_2 protein conserved in bacteria - - - 6.762e-220 709.0
HKD1_k127_4505964_20 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001131 266.0
HKD1_k127_4505964_21 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001726 260.0
HKD1_k127_4505964_22 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000004519 241.0
HKD1_k127_4505964_23 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000001671 231.0
HKD1_k127_4505964_24 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000103 224.0
HKD1_k127_4505964_25 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000004567 224.0
HKD1_k127_4505964_26 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000001703 218.0
HKD1_k127_4505964_27 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000001937 213.0
HKD1_k127_4505964_28 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000001003 213.0
HKD1_k127_4505964_29 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001283 206.0
HKD1_k127_4505964_3 Elongation factor G, domain IV K02355 - - 2.511e-211 671.0
HKD1_k127_4505964_30 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000008389 202.0
HKD1_k127_4505964_31 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000005363 203.0
HKD1_k127_4505964_32 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000008049 203.0
HKD1_k127_4505964_33 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000001785 189.0
HKD1_k127_4505964_34 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000001158 190.0
HKD1_k127_4505964_35 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000127 184.0
HKD1_k127_4505964_36 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000001629 186.0
HKD1_k127_4505964_37 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000678 184.0
HKD1_k127_4505964_38 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000007204 188.0
HKD1_k127_4505964_39 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000006187 166.0
HKD1_k127_4505964_4 Cystathionine beta-synthase K01697 - 4.2.1.22 1.177e-200 633.0
HKD1_k127_4505964_40 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000004778 170.0
HKD1_k127_4505964_41 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000902 158.0
HKD1_k127_4505964_42 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000105 153.0
HKD1_k127_4505964_43 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast K02881 - - 0.00000000000000000000000000000000000002918 147.0
HKD1_k127_4505964_45 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000005087 140.0
HKD1_k127_4505964_46 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000001042 136.0
HKD1_k127_4505964_47 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001226 138.0
HKD1_k127_4505964_48 - - - - 0.0000000000000000000000000000009309 135.0
HKD1_k127_4505964_5 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 606.0
HKD1_k127_4505964_50 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000004357 121.0
HKD1_k127_4505964_51 - - - - 0.0000000000000000000000000003331 128.0
HKD1_k127_4505964_52 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000001006 98.0
HKD1_k127_4505964_53 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000002524 108.0
HKD1_k127_4505964_54 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000006542 98.0
HKD1_k127_4505964_55 Protein of unknown function (DUF952) - - - 0.0000000000000001675 90.0
HKD1_k127_4505964_56 PFAM Photosynthetic reaction centre cytochrome C subunit K13992 - - 0.0000000000000003113 85.0
HKD1_k127_4505964_57 - - - - 0.0000000000000003412 90.0
HKD1_k127_4505964_58 PFAM blue (type 1) copper domain protein - - - 0.00000000000003637 79.0
HKD1_k127_4505964_59 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000006473 69.0
HKD1_k127_4505964_6 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 557.0
HKD1_k127_4505964_60 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000006416 76.0
HKD1_k127_4505964_61 Ribosomal protein L30p/L7e K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000009157 67.0
HKD1_k127_4505964_62 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000006253 60.0
HKD1_k127_4505964_63 PFAM blue (type 1) copper domain protein - - - 0.0001096 51.0
HKD1_k127_4505964_64 - - - - 0.0002045 50.0
HKD1_k127_4505964_65 intracellular chloride channel activity - - - 0.0004452 52.0
HKD1_k127_4505964_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 473.0
HKD1_k127_4505964_8 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 476.0
HKD1_k127_4505964_9 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 466.0
HKD1_k127_451166_0 radical SAM domain protein - - - 1.356e-287 894.0
HKD1_k127_451166_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.085e-272 856.0
HKD1_k127_451166_10 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 377.0
HKD1_k127_451166_11 Metallopeptidase family M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 368.0
HKD1_k127_451166_12 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 316.0
HKD1_k127_451166_13 serine-type endopeptidase activity K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 306.0
HKD1_k127_451166_14 beta' subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000002251 268.0
HKD1_k127_451166_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001927 251.0
HKD1_k127_451166_16 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000003223 261.0
HKD1_k127_451166_17 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000001059 248.0
HKD1_k127_451166_18 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000000000000000000000000005204 221.0
HKD1_k127_451166_19 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000007633 242.0
HKD1_k127_451166_2 Carbohydrate phosphorylase K00688 - 2.4.1.1 2.47e-248 804.0
HKD1_k127_451166_20 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000008552 238.0
HKD1_k127_451166_21 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000001289 229.0
HKD1_k127_451166_22 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000181 209.0
HKD1_k127_451166_23 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000001942 224.0
HKD1_k127_451166_24 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000008783 220.0
HKD1_k127_451166_25 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000001229 216.0
HKD1_k127_451166_26 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000001313 184.0
HKD1_k127_451166_27 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000003052 206.0
HKD1_k127_451166_28 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000004542 190.0
HKD1_k127_451166_29 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000008394 166.0
HKD1_k127_451166_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 9.501e-231 744.0
HKD1_k127_451166_30 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000008149 160.0
HKD1_k127_451166_31 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000007856 156.0
HKD1_k127_451166_32 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000007636 130.0
HKD1_k127_451166_33 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000003025 129.0
HKD1_k127_451166_34 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000003452 111.0
HKD1_k127_451166_35 CYTH K05873 - 4.6.1.1 0.000000000000000000000003989 110.0
HKD1_k127_451166_36 Protein of unknown function with PCYCGC motif - - - 0.00000000000000000000005155 106.0
HKD1_k127_451166_37 Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation K02485,K07315 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009893,GO:0010556,GO:0010604,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031647,GO:0031648,GO:0032268,GO:0032270,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0140110,GO:1903506,GO:2001141 3.1.3.3 0.00000000000000001852 89.0
HKD1_k127_451166_38 lipolytic protein G-D-S-L family K20306 - - 0.00000000000000007086 94.0
HKD1_k127_451166_39 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.0000000000000008016 81.0
HKD1_k127_451166_4 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 3.756e-196 621.0
HKD1_k127_451166_40 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000001944 74.0
HKD1_k127_451166_41 PrcB C-terminal - - - 0.000000006016 70.0
HKD1_k127_451166_42 Cupredoxin-like domain K00376 - 1.7.2.4 0.00000001654 61.0
HKD1_k127_451166_44 glycoside hydrolase family 81 - - - 0.0000837 56.0
HKD1_k127_451166_45 - - - - 0.0004641 55.0
HKD1_k127_451166_5 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 548.0
HKD1_k127_451166_6 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 507.0
HKD1_k127_451166_7 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 441.0
HKD1_k127_451166_8 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 416.0
HKD1_k127_451166_9 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 381.0
HKD1_k127_4523825_0 Dienelactone hydrolase family - - - 2.799e-247 788.0
HKD1_k127_4523825_1 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 606.0
HKD1_k127_4523825_2 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 527.0
HKD1_k127_4523825_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 502.0
HKD1_k127_4523825_4 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 432.0
HKD1_k127_4523825_5 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 403.0
HKD1_k127_4523825_6 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001198 284.0
HKD1_k127_4523825_7 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000003593 228.0
HKD1_k127_4523825_8 DinB family - - - 0.000000000000000000000000000000000000002635 154.0
HKD1_k127_4523825_9 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000000000009432 144.0
HKD1_k127_4524949_0 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 599.0
HKD1_k127_4524949_1 Penicillinase repressor - - - 0.000000000000000000000000000000000000000007007 158.0
HKD1_k127_4524949_2 - K01286 - 3.4.16.4 0.000000000000000000000000000000000003124 149.0
HKD1_k127_4525834_0 serine dehydratase beta chain K01752 - 4.3.1.17 8.028e-248 787.0
HKD1_k127_4525834_1 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 529.0
HKD1_k127_4525834_2 Protein of unknown function, DUF481 - - - 0.000000000000000000000000000000001979 140.0
HKD1_k127_4525834_3 Tfp pilus assembly protein FimV - - - 0.0000000000000006607 81.0
HKD1_k127_4651505_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.251e-269 841.0
HKD1_k127_4651505_1 ASPIC and UnbV - - - 1.81e-259 820.0
HKD1_k127_4651505_10 ATP-dependent helicase K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 372.0
HKD1_k127_4651505_11 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 360.0
HKD1_k127_4651505_12 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 349.0
HKD1_k127_4651505_13 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 341.0
HKD1_k127_4651505_14 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 323.0
HKD1_k127_4651505_15 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 336.0
HKD1_k127_4651505_16 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 304.0
HKD1_k127_4651505_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 317.0
HKD1_k127_4651505_18 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 316.0
HKD1_k127_4651505_19 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002024 286.0
HKD1_k127_4651505_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 581.0
HKD1_k127_4651505_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001712 275.0
HKD1_k127_4651505_21 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000361 266.0
HKD1_k127_4651505_22 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001107 265.0
HKD1_k127_4651505_23 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001921 280.0
HKD1_k127_4651505_24 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004475 266.0
HKD1_k127_4651505_25 Threonyl alanyl tRNA synthetase SAD K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000001771 272.0
HKD1_k127_4651505_26 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009484 257.0
HKD1_k127_4651505_27 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000002435 251.0
HKD1_k127_4651505_28 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000001401 252.0
HKD1_k127_4651505_29 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005103 249.0
HKD1_k127_4651505_3 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 491.0
HKD1_k127_4651505_30 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000517 253.0
HKD1_k127_4651505_31 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000401 248.0
HKD1_k127_4651505_32 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000001932 223.0
HKD1_k127_4651505_33 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000019 222.0
HKD1_k127_4651505_34 Subtilase family K17734 - - 0.000000000000000000000000000000000000000000000000000000007972 223.0
HKD1_k127_4651505_35 SpoU rRNA Methylase family - - - 0.0000000000000000000000000000000000000000000000000000004644 207.0
HKD1_k127_4651505_36 ATP-dependent helicase K03579 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000002616 201.0
HKD1_k127_4651505_37 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000001483 201.0
HKD1_k127_4651505_38 - - - - 0.00000000000000000000000000000000000000000000000002007 186.0
HKD1_k127_4651505_39 DinB superfamily - - - 0.0000000000000000000000000000000000000000000003084 173.0
HKD1_k127_4651505_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 469.0
HKD1_k127_4651505_40 - - - - 0.000000000000000000000000000000000000000000000599 181.0
HKD1_k127_4651505_41 - - - - 0.000000000000000000000000000000000000000000002455 169.0
HKD1_k127_4651505_42 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000007903 183.0
HKD1_k127_4651505_43 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000759 165.0
HKD1_k127_4651505_44 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000001202 174.0
HKD1_k127_4651505_45 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000001737 177.0
HKD1_k127_4651505_46 ethanolamine catabolic process K04027 - - 0.00000000000000000000000000000000000001523 145.0
HKD1_k127_4651505_47 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000000154 151.0
HKD1_k127_4651505_48 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000004215 145.0
HKD1_k127_4651505_49 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000001128 143.0
HKD1_k127_4651505_5 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 471.0
HKD1_k127_4651505_50 DinB superfamily - - - 0.00000000000000000000000000002365 126.0
HKD1_k127_4651505_51 DinB family - - - 0.0000000000000000000000000006956 118.0
HKD1_k127_4651505_52 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.00000000000000000000000002129 110.0
HKD1_k127_4651505_53 ioli protein K06606 - 5.3.99.11 0.00000000000000000000000004056 119.0
HKD1_k127_4651505_54 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000002498 120.0
HKD1_k127_4651505_55 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.000000000000000000002299 96.0
HKD1_k127_4651505_56 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.00000000000000000001541 93.0
HKD1_k127_4651505_57 Tetratricopeptide repeat - - - 0.000000000000000003237 93.0
HKD1_k127_4651505_58 Acetyltransferase (GNAT) domain - - - 0.00000000000000001058 93.0
HKD1_k127_4651505_59 Protein of unknown function (DUF2911) - - - 0.00000000000000001276 93.0
HKD1_k127_4651505_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 452.0
HKD1_k127_4651505_60 Nodulation protein S (NodS) - - - 0.0000000000000009982 87.0
HKD1_k127_4651505_61 Unextendable partial coding region - - - 0.000000000006014 66.0
HKD1_k127_4651505_63 Heat shock 70 kDa protein K04043 - - 0.0000003356 59.0
HKD1_k127_4651505_64 GDSL-like Lipase/Acylhydrolase - - - 0.000006019 58.0
HKD1_k127_4651505_65 peptidyl-tyrosine sulfation - - - 0.00004285 55.0
HKD1_k127_4651505_66 YbbR-like protein - - - 0.0003295 53.0
HKD1_k127_4651505_67 SMART TRASH domain protein - - - 0.0003469 52.0
HKD1_k127_4651505_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 451.0
HKD1_k127_4651505_8 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 404.0
HKD1_k127_4651505_9 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 377.0
HKD1_k127_466121_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 7.964e-209 666.0
HKD1_k127_466121_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000001418 200.0
HKD1_k127_4664013_0 alpha-L-rhamnosidase - - - 2.315e-236 751.0
HKD1_k127_4664013_1 glycoside hydrolase family 2 sugar binding - - - 0.000000000000000000001078 95.0
HKD1_k127_4693609_0 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000003344 174.0
HKD1_k127_4693609_1 antisigma factor binding K04749 - - 0.00001303 55.0
HKD1_k127_4693609_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0003688 44.0
HKD1_k127_4713263_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1356.0
HKD1_k127_4713263_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1255.0
HKD1_k127_4713263_10 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 380.0
HKD1_k127_4713263_11 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 339.0
HKD1_k127_4713263_12 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 363.0
HKD1_k127_4713263_13 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 333.0
HKD1_k127_4713263_14 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 345.0
HKD1_k127_4713263_15 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 319.0
HKD1_k127_4713263_16 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005975 283.0
HKD1_k127_4713263_17 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001126 289.0
HKD1_k127_4713263_18 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007174 263.0
HKD1_k127_4713263_19 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002141 254.0
HKD1_k127_4713263_2 Carboxypeptidase regulatory-like domain - - - 3e-323 1025.0
HKD1_k127_4713263_20 ribonuclease inhibitor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002126 244.0
HKD1_k127_4713263_21 PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000004331 239.0
HKD1_k127_4713263_22 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000642 232.0
HKD1_k127_4713263_23 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000004952 222.0
HKD1_k127_4713263_24 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000001071 210.0
HKD1_k127_4713263_25 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000001688 201.0
HKD1_k127_4713263_26 VIT family - - - 0.00000000000000000000000000000000000000000000000000001887 197.0
HKD1_k127_4713263_27 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000007482 207.0
HKD1_k127_4713263_28 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000001625 193.0
HKD1_k127_4713263_29 Alginate export - - - 0.0000000000000000000000000000000000000000000000000002138 203.0
HKD1_k127_4713263_3 Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 449.0
HKD1_k127_4713263_30 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.0000000000000000000000000000000000000000000005413 179.0
HKD1_k127_4713263_31 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000000001247 167.0
HKD1_k127_4713263_32 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000002922 181.0
HKD1_k127_4713263_33 - - - - 0.0000000000000000000000000000000000000002886 170.0
HKD1_k127_4713263_34 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000002405 132.0
HKD1_k127_4713263_35 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000005019 126.0
HKD1_k127_4713263_36 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.0000000000000000000000002816 115.0
HKD1_k127_4713263_37 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000001055 111.0
HKD1_k127_4713263_38 CHAD - - - 0.000000002882 68.0
HKD1_k127_4713263_39 PEP-CTERM motif - - - 0.00000006498 63.0
HKD1_k127_4713263_4 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 440.0
HKD1_k127_4713263_40 Disulphide bond corrector protein DsbC - - - 0.00000269 60.0
HKD1_k127_4713263_5 Belongs to the PstS family K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 409.0
HKD1_k127_4713263_6 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 402.0
HKD1_k127_4713263_7 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 398.0
HKD1_k127_4713263_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008685 378.0
HKD1_k127_4713263_9 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 382.0
HKD1_k127_4910797_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 1.808e-223 720.0
HKD1_k127_4910797_1 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 522.0
HKD1_k127_4910797_10 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 344.0
HKD1_k127_4910797_11 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 314.0
HKD1_k127_4910797_12 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003442 280.0
HKD1_k127_4910797_13 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005285 253.0
HKD1_k127_4910797_14 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001125 262.0
HKD1_k127_4910797_15 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000002607 233.0
HKD1_k127_4910797_16 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000001658 235.0
HKD1_k127_4910797_17 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000003135 231.0
HKD1_k127_4910797_18 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000004112 232.0
HKD1_k127_4910797_19 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000009038 206.0
HKD1_k127_4910797_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 506.0
HKD1_k127_4910797_20 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000008228 170.0
HKD1_k127_4910797_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000002007 151.0
HKD1_k127_4910797_22 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000009695 158.0
HKD1_k127_4910797_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000001983 143.0
HKD1_k127_4910797_24 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000001473 141.0
HKD1_k127_4910797_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000004419 127.0
HKD1_k127_4910797_26 Cytochrome C assembly protein - - - 0.0000000000000000000000000978 118.0
HKD1_k127_4910797_27 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000008777 108.0
HKD1_k127_4910797_28 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000001528 90.0
HKD1_k127_4910797_29 von Willebrand factor, type A K07114 - - 0.000000000000009661 85.0
HKD1_k127_4910797_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 495.0
HKD1_k127_4910797_30 - - - - 0.0000000000144 67.0
HKD1_k127_4910797_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 467.0
HKD1_k127_4910797_5 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 452.0
HKD1_k127_4910797_6 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007594 426.0
HKD1_k127_4910797_7 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 403.0
HKD1_k127_4910797_8 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 375.0
HKD1_k127_4910797_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 368.0
HKD1_k127_4958207_0 PQQ-like domain K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 451.0
HKD1_k127_5013736_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 520.0
HKD1_k127_5013736_1 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 429.0
HKD1_k127_5013736_10 - - - - 0.000000000000000000000000001837 123.0
HKD1_k127_5013736_11 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000004963 77.0
HKD1_k127_5013736_2 epoxide hydrolase K21159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 406.0
HKD1_k127_5013736_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005338 299.0
HKD1_k127_5013736_4 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000385 256.0
HKD1_k127_5013736_5 cellulase activity - - - 0.00000000000000000000000000000000000000000000005995 188.0
HKD1_k127_5013736_6 - - - - 0.0000000000000000000000000000000000000000005946 171.0
HKD1_k127_5013736_7 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000001044 157.0
HKD1_k127_5013736_8 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000006316 153.0
HKD1_k127_5013736_9 Outer membrane receptor - - - 0.00000000000000000000000000001399 138.0
HKD1_k127_5048673_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 3.205e-243 775.0
HKD1_k127_5048673_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 332.0
HKD1_k127_5048673_2 ABC transporter K02003 - - 0.000000000000000000003245 94.0
HKD1_k127_5048673_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0009782 49.0
HKD1_k127_5049931_0 Amino acid permease - - - 3.309e-233 743.0
HKD1_k127_5049931_1 mannose metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 360.0
HKD1_k127_5049931_2 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.000000000001162 68.0
HKD1_k127_5049971_0 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 569.0
HKD1_k127_5049971_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000239 174.0
HKD1_k127_5077525_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 5.299e-195 623.0
HKD1_k127_5077525_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 547.0
HKD1_k127_5077525_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 415.0
HKD1_k127_5077525_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000009236 176.0
HKD1_k127_5077525_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000009543 112.0
HKD1_k127_5077525_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000001065 71.0
HKD1_k127_5077525_6 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00002399 50.0
HKD1_k127_5077525_7 Carboxypeptidase regulatory-like domain - - - 0.0002036 47.0
HKD1_k127_5084088_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.727e-287 898.0
HKD1_k127_5084088_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000004953 233.0
HKD1_k127_5084088_2 TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000007671 162.0
HKD1_k127_5084088_3 Domain of unknown function (DUF1850) - - - 0.000000000000000000000000000003525 138.0
HKD1_k127_5084088_4 Rhodanese Homology Domain - - - 0.00000000000000000003478 97.0
HKD1_k127_509857_0 amidase activity K01426 - 3.5.1.4 2.608e-244 770.0
HKD1_k127_509857_1 PFAM Radical SAM - - - 2.555e-210 672.0
HKD1_k127_509857_10 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001336 271.0
HKD1_k127_509857_11 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000006822 263.0
HKD1_k127_509857_12 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000002216 236.0
HKD1_k127_509857_13 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000001078 222.0
HKD1_k127_509857_14 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000005012 191.0
HKD1_k127_509857_15 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000451 181.0
HKD1_k127_509857_16 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000004497 173.0
HKD1_k127_509857_17 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000006755 170.0
HKD1_k127_509857_18 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000002143 140.0
HKD1_k127_509857_19 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000003954 150.0
HKD1_k127_509857_2 DNA topological change K03168 - 5.99.1.2 2.241e-203 681.0
HKD1_k127_509857_20 negative regulation of translational initiation - - - 0.0000000000000000000000000000000009417 139.0
HKD1_k127_509857_21 Protein conserved in bacteria - - - 0.00000000000000000000000152 106.0
HKD1_k127_509857_22 PHD zinc finger K09187,K09188 GO:0000003,GO:0000981,GO:0001067,GO:0001555,GO:0001701,GO:0002682,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006325,GO:0006342,GO:0006355,GO:0006357,GO:0006464,GO:0006479,GO:0006807,GO:0006996,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008284,GO:0008757,GO:0009790,GO:0009792,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0009994,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0016043,GO:0016049,GO:0016278,GO:0016279,GO:0016458,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018022,GO:0018024,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023056,GO:0030154,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031974,GO:0031981,GO:0032259,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033143,GO:0033145,GO:0033146,GO:0033148,GO:0034708,GO:0034968,GO:0035097,GO:0036211,GO:0040007,GO:0040028,GO:0040029,GO:0042054,GO:0042127,GO:0042800,GO:0043009,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043627,GO:0043933,GO:0044085,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044666,GO:0044703,GO:0045595,GO:0045637,GO:0045652,GO:0045814,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0048468,GO:0048477,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048580,GO:0048583,GO:0048584,GO:0048588,GO:0048589,GO:0048599,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051568,GO:0051704,GO:0060255,GO:0061062,GO:0065003,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:0140096,GO:0140110,GO:1901363,GO:1901564,GO:1902494,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1903706,GO:1904837,GO:1990234,GO:2000026,GO:2000112,GO:2000113,GO:2001141 2.1.1.43 0.0000000000000000000001619 107.0
HKD1_k127_509857_23 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.00000000000000000007025 90.0
HKD1_k127_509857_24 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000002537 82.0
HKD1_k127_509857_25 - - - - 0.0000000000005094 74.0
HKD1_k127_509857_26 serine-type endopeptidase activity - - - 0.00000000001533 73.0
HKD1_k127_509857_27 cheY-homologous receiver domain - - - 0.0000000002539 66.0
HKD1_k127_509857_28 TadE-like protein - - - 0.000000008267 63.0
HKD1_k127_509857_29 - - - - 0.0000002811 61.0
HKD1_k127_509857_3 - - - - 3.509e-195 625.0
HKD1_k127_509857_30 - - - - 0.00005438 54.0
HKD1_k127_509857_4 COG2303 Choline dehydrogenase and related flavoproteins K03333 - 1.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 596.0
HKD1_k127_509857_5 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 493.0
HKD1_k127_509857_6 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 482.0
HKD1_k127_509857_7 ankyrin repeat K15503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 417.0
HKD1_k127_509857_8 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 398.0
HKD1_k127_509857_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 361.0
HKD1_k127_5107883_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 425.0
HKD1_k127_5107883_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 378.0
HKD1_k127_5107883_2 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 329.0
HKD1_k127_5107883_3 GTP-binding protein TypA K06207 - - 0.000000000000000000009463 92.0
HKD1_k127_5107883_4 Biotin-lipoyl like K03585 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0006869,GO:0008150,GO:0010876,GO:0015238,GO:0015711,GO:0015718,GO:0015721,GO:0015849,GO:0015850,GO:0015893,GO:0016020,GO:0022857,GO:0031224,GO:0031226,GO:0033036,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.000001145 51.0
HKD1_k127_5110821_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 474.0
HKD1_k127_5110821_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 353.0
HKD1_k127_5110821_2 Acyl-homoserine-lactone synthase K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000004137 197.0
HKD1_k127_5110821_3 - - - - 0.0000000000000000000000000005773 120.0
HKD1_k127_5110824_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 356.0
HKD1_k127_5110824_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 301.0
HKD1_k127_5110824_2 Acyl-homoserine-lactone synthase K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000001591 194.0
HKD1_k127_5110824_3 - - - - 0.00000000000000000000000000202 118.0
HKD1_k127_5118874_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 469.0
HKD1_k127_5118874_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 324.0
HKD1_k127_5118874_2 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000001395 190.0
HKD1_k127_5118874_3 PFAM Organic solvent tolerance protein K04744 - - 0.00000000002074 73.0
HKD1_k127_5126902_0 Sulfatase K01130 - 3.1.6.1 0.0 1332.0
HKD1_k127_5126902_1 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 521.0
HKD1_k127_5126902_10 long-chain fatty acid transport protein - - - 0.0000000000000851 81.0
HKD1_k127_5126902_11 - - - - 0.0000000000002478 79.0
HKD1_k127_5126902_12 - - - - 0.000000000008333 79.0
HKD1_k127_5126902_13 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000006472 55.0
HKD1_k127_5126902_14 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00001084 58.0
HKD1_k127_5126902_15 Abortive infection protein K07052 - - 0.00005769 54.0
HKD1_k127_5126902_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 401.0
HKD1_k127_5126902_3 - - - - 0.00000000000000000000000000000000000000000000000001022 189.0
HKD1_k127_5126902_4 CoA binding domain K06929 - - 0.0000000000000000000000000000000000003877 154.0
HKD1_k127_5126902_5 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000003445 156.0
HKD1_k127_5126902_6 KR domain - - - 0.00000000000000000000000000000000002467 155.0
HKD1_k127_5126902_7 NHL repeat - - - 0.0000000000000000000000000000002315 138.0
HKD1_k127_5126902_8 Predicted nucleotide-binding protein containing TIR-like domain - - - 0.00000000000000000000000000103 125.0
HKD1_k127_5126902_9 - - - - 0.00000000000000000003763 97.0
HKD1_k127_5146383_0 - - - - 0.00000000000000000000000000000000000008396 152.0
HKD1_k127_5146383_1 Tetratricopeptide repeat - - - 0.00000005124 66.0
HKD1_k127_5165448_0 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 475.0
HKD1_k127_5165448_1 COG2015, Alkyl sulfatase and related hydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 387.0
HKD1_k127_5165448_10 PFAM regulatory protein, MarR - - - 0.0000000000000000000008757 101.0
HKD1_k127_5165448_11 - - - - 0.00005664 49.0
HKD1_k127_5165448_2 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 342.0
HKD1_k127_5165448_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004146 281.0
HKD1_k127_5165448_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000861 232.0
HKD1_k127_5165448_5 Putative zinc-finger - - - 0.000000000000000000000000000000000000000000000000000000009079 208.0
HKD1_k127_5165448_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000006413 181.0
HKD1_k127_5165448_7 Cyclic nucleotide-monophosphate binding domain K01420 - - 0.0000000000000000000000000000000001093 141.0
HKD1_k127_5165448_8 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000002641 116.0
HKD1_k127_5165448_9 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.000000000000000000000000004728 127.0
HKD1_k127_5174141_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1195.0
HKD1_k127_5198621_0 AcrB/AcrD/AcrF family - - - 0.0 1170.0
HKD1_k127_5198621_1 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 372.0
HKD1_k127_5198621_10 Outer membrane efflux protein - - - 0.000000000000000000000000000000000004997 158.0
HKD1_k127_5198621_11 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000007923 145.0
HKD1_k127_5198621_12 Putative zinc-finger K03088 - - 0.00000000000000000000000004364 121.0
HKD1_k127_5198621_13 Sulfurtransferase - - - 0.00000000000000000005375 90.0
HKD1_k127_5198621_14 Tetratricopeptide repeat - - - 0.0000000000000000001248 104.0
HKD1_k127_5198621_15 RNA polymerase K03088 - - 0.0003561 48.0
HKD1_k127_5198621_2 Domain of unknown function (DUF4071) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 349.0
HKD1_k127_5198621_3 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 304.0
HKD1_k127_5198621_4 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003157 277.0
HKD1_k127_5198621_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000177 253.0
HKD1_k127_5198621_6 competence protein COMEC K02238 - - 0.0000000000000000000000000000000000000000000000000000000002781 218.0
HKD1_k127_5198621_7 conserved protein - - - 0.0000000000000000000000000000000000000000000000006547 190.0
HKD1_k127_5198621_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000002974 174.0
HKD1_k127_5198621_9 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000004176 178.0
HKD1_k127_5200748_0 xanthine dehydrogenase activity - - - 0.0 1047.0
HKD1_k127_5200748_1 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002678 278.0
HKD1_k127_5200748_2 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000003768 248.0
HKD1_k127_5200748_3 InterPro IPR014922 - - - 0.0000000000000000000000000000000000000000000000000000000001033 213.0
HKD1_k127_5200748_4 - - - - 0.00000000000000000000000000000000000000000004697 169.0
HKD1_k127_5200748_5 YCII-related domain - - - 0.000000000000000000000000000000000004867 139.0
HKD1_k127_5200748_6 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.0000000000000000000000000000004954 123.0
HKD1_k127_5200748_7 - - - - 0.00000000000000000000000004622 109.0
HKD1_k127_5201348_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1193.0
HKD1_k127_5201348_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1073.0
HKD1_k127_5201348_10 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 305.0
HKD1_k127_5201348_12 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000009562 247.0
HKD1_k127_5201348_13 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000001146 252.0
HKD1_k127_5201348_14 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000009629 244.0
HKD1_k127_5201348_15 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000005449 199.0
HKD1_k127_5201348_16 COG3258 Cytochrome c K19713 - 1.8.2.2 0.00000000000000000000000000000000000000000000004511 186.0
HKD1_k127_5201348_17 Peptidase family M23 - - - 0.0000000000000000000000000000000000000007055 160.0
HKD1_k127_5201348_18 BMC K04027 - - 0.000000000000000000000000000000000000005267 147.0
HKD1_k127_5201348_19 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000005646 161.0
HKD1_k127_5201348_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 582.0
HKD1_k127_5201348_20 transglycosylase K08309 - - 0.000000000000000000000000000000001738 137.0
HKD1_k127_5201348_21 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000001399 127.0
HKD1_k127_5201348_22 domain protein K14194 - - 0.0000000000000000000000000005379 132.0
HKD1_k127_5201348_23 Helix-hairpin-helix motif - - - 0.000000000000000000005054 97.0
HKD1_k127_5201348_24 - - - - 0.000000000000000002836 97.0
HKD1_k127_5201348_25 COG1555 DNA uptake protein and related DNA-binding proteins K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000002413 80.0
HKD1_k127_5201348_26 Putative phosphatase (DUF442) - - - 0.000000006317 64.0
HKD1_k127_5201348_27 Protein of unknown function (DUF1634) - - - 0.0000047 59.0
HKD1_k127_5201348_28 Sulfatase K01133 - 3.1.6.6 0.0001653 53.0
HKD1_k127_5201348_3 PFAM magnesium chelatase K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 550.0
HKD1_k127_5201348_4 TIGRFAM acetaldehyde dehydrogenase (acetylating) K00132 - 1.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 501.0
HKD1_k127_5201348_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 432.0
HKD1_k127_5201348_6 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 387.0
HKD1_k127_5201348_7 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 377.0
HKD1_k127_5201348_8 PFAM Type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 375.0
HKD1_k127_5201348_9 PFAM beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 344.0
HKD1_k127_5207846_0 Dehydrogenase K00114 - 1.1.2.8 2.173e-196 628.0
HKD1_k127_5207846_1 PFAM major facilitator superfamily MFS_1 K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 533.0
HKD1_k127_5207846_10 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000001659 166.0
HKD1_k127_5207846_11 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000003392 84.0
HKD1_k127_5207846_2 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 445.0
HKD1_k127_5207846_3 SMP-30/Gluconolaconase/LRE-like region K01053,K13735 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 437.0
HKD1_k127_5207846_4 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 415.0
HKD1_k127_5207846_5 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 299.0
HKD1_k127_5207846_6 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004005 282.0
HKD1_k127_5207846_7 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000000000000000001883 190.0
HKD1_k127_5207846_8 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000000000005463 171.0
HKD1_k127_5207846_9 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K03737 - 1.2.7.1 0.000000000000000000000000000000000000000009487 159.0
HKD1_k127_5240330_0 PKD domain - - - 0.0000000000000000000000000000001102 143.0
HKD1_k127_5240330_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03321 - - 0.00000000000000000000000000001801 123.0
HKD1_k127_5240330_2 general secretion pathway protein - - - 0.000000000000000000006537 108.0
HKD1_k127_5296555_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1110.0
HKD1_k127_5296555_1 Angiotensin-converting enzyme K01283 - 3.4.15.1 4.06e-259 807.0
HKD1_k127_5296555_10 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000003621 178.0
HKD1_k127_5296555_11 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000002856 179.0
HKD1_k127_5296555_12 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000003181 151.0
HKD1_k127_5296555_13 - - - - 0.000000000000000000000000000000000003303 148.0
HKD1_k127_5296555_14 cheY-homologous receiver domain - - - 0.00000000000000000000000000000005267 137.0
HKD1_k127_5296555_15 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000002984 134.0
HKD1_k127_5296555_16 cell adhesion - - - 0.000001576 61.0
HKD1_k127_5296555_17 Sporulation related domain - - - 0.0006898 50.0
HKD1_k127_5296555_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.683e-230 724.0
HKD1_k127_5296555_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 3.049e-194 626.0
HKD1_k127_5296555_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 498.0
HKD1_k127_5296555_5 Dehydrogenase K00248,K09478 - 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 295.0
HKD1_k127_5296555_6 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 294.0
HKD1_k127_5296555_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000006977 265.0
HKD1_k127_5296555_8 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000001622 202.0
HKD1_k127_5296555_9 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000005401 213.0
HKD1_k127_5306457_1 F5/8 type C domain - - - 0.0000000000000000000001361 107.0
HKD1_k127_5374218_0 Carboxypeptidase regulatory-like domain - - - 7.083e-299 941.0
HKD1_k127_5379514_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1041.0
HKD1_k127_5379514_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 3.47e-280 873.0
HKD1_k127_5379514_10 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 345.0
HKD1_k127_5379514_11 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 325.0
HKD1_k127_5379514_12 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 314.0
HKD1_k127_5379514_13 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004196 271.0
HKD1_k127_5379514_14 Converts the prephenate produced from the shikimate- chorismate pathway into phenylalanine K05359 GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009507,GO:0009536,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047769,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51,4.2.1.91 0.0000000000000000000000000000000000000000000000000000000144 204.0
HKD1_k127_5379514_15 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000002859 186.0
HKD1_k127_5379514_16 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000006269 192.0
HKD1_k127_5379514_17 lipid kinase, YegS Rv2252 BmrU family - - - 0.000000000000000000000000000000000000000000005639 179.0
HKD1_k127_5379514_18 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000009671 168.0
HKD1_k127_5379514_19 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000001367 127.0
HKD1_k127_5379514_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.414e-236 740.0
HKD1_k127_5379514_20 Copper resistance protein D K07245 - - 0.00000000000000005517 88.0
HKD1_k127_5379514_21 Protein of unknown function (DUF2905) - - - 0.000000000003955 68.0
HKD1_k127_5379514_3 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 6.124e-220 688.0
HKD1_k127_5379514_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 513.0
HKD1_k127_5379514_5 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 498.0
HKD1_k127_5379514_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 428.0
HKD1_k127_5379514_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 414.0
HKD1_k127_5379514_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 403.0
HKD1_k127_5379514_9 Succinate dehydrogenase fumarate reductase Fe-S protein subunit K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 359.0
HKD1_k127_5410871_0 transmembrane transporter activity K03296,K07788,K07789 - - 0.0 1021.0
HKD1_k127_5410871_1 transmembrane transporter activity K03296,K07788,K07789 - - 0.0000000000000000000000000002863 115.0
HKD1_k127_5410872_0 transmembrane transporter activity K03296,K07788,K07789 - - 0.0 1446.0
HKD1_k127_5410872_1 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 1.378e-205 646.0
HKD1_k127_5410872_10 Flp Fap pilin component K02651 - - 0.0001414 46.0
HKD1_k127_5410872_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 426.0
HKD1_k127_5410872_3 Threonine/Serine exporter, ThrE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008908 417.0
HKD1_k127_5410872_4 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 330.0
HKD1_k127_5410872_5 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009066 324.0
HKD1_k127_5410872_6 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000005391 190.0
HKD1_k127_5410872_7 - - - - 0.000000000000000000000000000000000000001567 160.0
HKD1_k127_5410872_8 transmembrane transporter activity K03296,K07788,K07789 - - 0.0000000000000000000000000001448 116.0
HKD1_k127_5410872_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000001671 103.0
HKD1_k127_5433467_0 Dehydrogenase K14028 - 1.1.2.7 8.455e-253 792.0
HKD1_k127_5433467_1 Peptidase family M3 K01392 - 3.4.24.15 9.682e-212 680.0
HKD1_k127_5433467_10 amino acid transport K02030,K16254 - - 0.0000000000000000000000000000000000000000000000000000000000000001343 236.0
HKD1_k127_5433467_11 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000008018 214.0
HKD1_k127_5433467_12 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000005363 201.0
HKD1_k127_5433467_13 geranylgeranyl reductase activity K06444,K17830 - 1.3.1.101,1.3.7.11,5.5.1.18 0.000000000000000000000000000000000000000000000000002148 198.0
HKD1_k127_5433467_14 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000000000001001 188.0
HKD1_k127_5433467_15 asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000001261 187.0
HKD1_k127_5433467_16 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000001047 183.0
HKD1_k127_5433467_17 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000002812 177.0
HKD1_k127_5433467_18 macromolecule localization K01992,K09690 - - 0.0000000000000000000000000000000000000000006941 167.0
HKD1_k127_5433467_19 PRMT5 arginine-N-methyltransferase K11434 - 2.1.1.319 0.0000000000000000000000000000000000000006937 162.0
HKD1_k127_5433467_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 497.0
HKD1_k127_5433467_20 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000009793 134.0
HKD1_k127_5433467_21 Cytochrome c K16255 - - 0.000000000000000000000000002288 125.0
HKD1_k127_5433467_22 - - - - 0.00000000000000000000000000325 115.0
HKD1_k127_5433467_23 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000002593 115.0
HKD1_k127_5433467_24 HPr kinase - - - 0.00000000000000000003431 102.0
HKD1_k127_5433467_25 O-Antigen ligase K02847 - - 0.000000000000000001606 99.0
HKD1_k127_5433467_26 PFAM Glycosyl transferase family 2 - - - 0.000000000000004776 86.0
HKD1_k127_5433467_27 Glycosyl transferase 4-like domain - - - 0.00000000000004102 76.0
HKD1_k127_5433467_28 PFAM Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000001925 79.0
HKD1_k127_5433467_29 integral membrane protein K00728 - 2.4.1.109 0.00000000003537 77.0
HKD1_k127_5433467_3 LOR/SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 460.0
HKD1_k127_5433467_30 Transglutaminase-like superfamily - - - 0.00001798 55.0
HKD1_k127_5433467_4 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 406.0
HKD1_k127_5433467_5 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000624 353.0
HKD1_k127_5433467_6 Tannase and feruloyl esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 337.0
HKD1_k127_5433467_7 PFAM ABC transporter K01990,K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 332.0
HKD1_k127_5433467_8 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009804 275.0
HKD1_k127_5433467_9 tRNA pseudouridine synthase K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000706 254.0
HKD1_k127_5466426_0 Major facilitator superfamily MFS_1 - - - 1.007e-211 680.0
HKD1_k127_5466426_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 2.265e-208 683.0
HKD1_k127_5466426_10 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 392.0
HKD1_k127_5466426_11 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 357.0
HKD1_k127_5466426_12 abc transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 325.0
HKD1_k127_5466426_13 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009337 319.0
HKD1_k127_5466426_14 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 299.0
HKD1_k127_5466426_15 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 297.0
HKD1_k127_5466426_16 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002093 280.0
HKD1_k127_5466426_17 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001238 279.0
HKD1_k127_5466426_18 protein involved in propionate catabolism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001157 281.0
HKD1_k127_5466426_19 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001698 248.0
HKD1_k127_5466426_2 RESPONSE REGULATOR receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 604.0
HKD1_k127_5466426_20 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000121 235.0
HKD1_k127_5466426_21 PFAM Cache K08738 - - 0.000000000000000000000000000000000000000000000000000000000000003158 240.0
HKD1_k127_5466426_22 - - - - 0.00000000000000000000000000000000000000000000000000000000000039 223.0
HKD1_k127_5466426_23 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000002885 224.0
HKD1_k127_5466426_24 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000003516 208.0
HKD1_k127_5466426_25 - - - - 0.000000000000000000000000000000000000000000000000000001063 198.0
HKD1_k127_5466426_26 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000001229 200.0
HKD1_k127_5466426_27 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000001761 195.0
HKD1_k127_5466426_28 Cupin 2, conserved barrel domain protein K11312 - - 0.0000000000000000000000000000000000000000000000006926 182.0
HKD1_k127_5466426_29 Single Cache domain 2 K07647 - 2.7.13.3 0.00000000000000000000000000000000000000000001941 183.0
HKD1_k127_5466426_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 506.0
HKD1_k127_5466426_30 META domain K03929 - - 0.00000000000000000000000000000000000000000005872 179.0
HKD1_k127_5466426_31 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000007415 164.0
HKD1_k127_5466426_32 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000000000000009597 159.0
HKD1_k127_5466426_34 - - - - 0.0000000000000000000000000000009216 137.0
HKD1_k127_5466426_35 TonB dependent receptor - - - 0.00000000000000006097 96.0
HKD1_k127_5466426_36 Rhomboid family K19225 - 3.4.21.105 0.00000000000000101 90.0
HKD1_k127_5466426_39 Tetratricopeptide repeat - - - 0.000008319 57.0
HKD1_k127_5466426_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 512.0
HKD1_k127_5466426_5 cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 469.0
HKD1_k127_5466426_6 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 486.0
HKD1_k127_5466426_7 electron transfer activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 454.0
HKD1_k127_5466426_8 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 441.0
HKD1_k127_5466426_9 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 390.0
HKD1_k127_5478988_0 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 425.0
HKD1_k127_5478988_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 404.0
HKD1_k127_5478988_10 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001125 287.0
HKD1_k127_5478988_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004778 278.0
HKD1_k127_5478988_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001408 288.0
HKD1_k127_5478988_13 allophanate hydrolase subunit 2 K01457,K01941,K06350 - 3.5.1.54,6.3.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000004124 274.0
HKD1_k127_5478988_14 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.00000000000000000000000000000000000000000000000000000000000000000000002342 251.0
HKD1_k127_5478988_15 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.0000000000000000000000000000000000000000000000000000000000000001203 240.0
HKD1_k127_5478988_16 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000725 230.0
HKD1_k127_5478988_17 Allophanate hydrolase subunit 1 K06351 - - 0.00000000000000000000000000000000000000000000000000000000000004278 227.0
HKD1_k127_5478988_18 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000001364 213.0
HKD1_k127_5478988_19 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000004557 205.0
HKD1_k127_5478988_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 336.0
HKD1_k127_5478988_20 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000001703 198.0
HKD1_k127_5478988_21 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.000000000000000000000000000000000000000000000000000471 192.0
HKD1_k127_5478988_22 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000006312 194.0
HKD1_k127_5478988_23 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000007217 177.0
HKD1_k127_5478988_24 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000006771 169.0
HKD1_k127_5478988_25 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000006315 163.0
HKD1_k127_5478988_26 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000003905 168.0
HKD1_k127_5478988_27 - - - - 0.00000000000000000000000004441 121.0
HKD1_k127_5478988_28 - - - - 0.00000000000000000000000009353 111.0
HKD1_k127_5478988_29 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000001314 115.0
HKD1_k127_5478988_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 337.0
HKD1_k127_5478988_30 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000003202 119.0
HKD1_k127_5478988_31 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000003912 109.0
HKD1_k127_5478988_32 - - - - 0.0000000000000000000006852 109.0
HKD1_k127_5478988_33 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000006803 102.0
HKD1_k127_5478988_34 - - - - 0.0000000000155 76.0
HKD1_k127_5478988_35 SNARE associated Golgi protein - - - 0.0000000001551 68.0
HKD1_k127_5478988_36 Fimbrial assembly protein (PilN) K02663 - - 0.000000001203 71.0
HKD1_k127_5478988_37 Pilus assembly protein, PilP K02665 - - 0.000000004075 68.0
HKD1_k127_5478988_38 - - - - 0.00007775 56.0
HKD1_k127_5478988_39 Sigma-54 interaction domain - - - 0.0009536 48.0
HKD1_k127_5478988_4 pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 338.0
HKD1_k127_5478988_5 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 336.0
HKD1_k127_5478988_6 cytochrome K17230 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 334.0
HKD1_k127_5478988_7 Type ii and iii secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 336.0
HKD1_k127_5478988_8 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 323.0
HKD1_k127_5478988_9 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 313.0
HKD1_k127_548434_0 PFAM Radical SAM - - - 1.189e-221 702.0
HKD1_k127_5539322_0 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 302.0
HKD1_k127_5539322_1 RNA polymerase sigma factor K02405 - - 0.000000000006591 74.0
HKD1_k127_5539322_2 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000003256 63.0
HKD1_k127_5555149_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 402.0
HKD1_k127_5555149_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004904 274.0
HKD1_k127_5567373_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1178.0
HKD1_k127_5567373_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 8.681e-257 814.0
HKD1_k127_5567373_10 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 377.0
HKD1_k127_5567373_11 extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 349.0
HKD1_k127_5567373_12 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 295.0
HKD1_k127_5567373_13 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001031 310.0
HKD1_k127_5567373_14 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004945 286.0
HKD1_k127_5567373_15 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003234 262.0
HKD1_k127_5567373_16 tyrosine recombinase XerC K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003682 263.0
HKD1_k127_5567373_17 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008234 259.0
HKD1_k127_5567373_18 Belongs to the DapA family K18123 - 4.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000007945 247.0
HKD1_k127_5567373_19 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000005143 239.0
HKD1_k127_5567373_2 C-terminus of AA_permease K03294 - - 1.318e-218 687.0
HKD1_k127_5567373_20 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000548 223.0
HKD1_k127_5567373_21 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000001597 205.0
HKD1_k127_5567373_22 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000001924 210.0
HKD1_k127_5567373_23 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000004589 214.0
HKD1_k127_5567373_24 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000005104 201.0
HKD1_k127_5567373_25 ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component - - - 0.0000000000000000000000000000000000000000000000001335 184.0
HKD1_k127_5567373_26 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000006171 181.0
HKD1_k127_5567373_27 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000006778 167.0
HKD1_k127_5567373_28 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000001653 153.0
HKD1_k127_5567373_29 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000005701 143.0
HKD1_k127_5567373_3 H( )-stimulated, divalent metal cation uptake system K03322 - - 4.612e-201 634.0
HKD1_k127_5567373_30 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000823 155.0
HKD1_k127_5567373_31 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K01488 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 0.00000000000000000000000000000000002277 154.0
HKD1_k127_5567373_32 NlpC P60 family protein - - - 0.0000000000000000000000000000000218 132.0
HKD1_k127_5567373_33 Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000006231 136.0
HKD1_k127_5567373_34 thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000003633 131.0
HKD1_k127_5567373_35 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000001051 126.0
HKD1_k127_5567373_36 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000437 123.0
HKD1_k127_5567373_37 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000004391 109.0
HKD1_k127_5567373_38 Phosphoribosyl transferase domain - - - 0.000000000000000000000007274 115.0
HKD1_k127_5567373_39 domain protein - - - 0.0000000000000000000001944 110.0
HKD1_k127_5567373_4 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 619.0
HKD1_k127_5567373_40 radical SAM domain protein - - - 0.000000000000000000000969 109.0
HKD1_k127_5567373_41 response regulator - - - 0.00000000000000000003148 101.0
HKD1_k127_5567373_43 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000001099 81.0
HKD1_k127_5567373_44 STAS domain K04749 - - 0.0000000002981 72.0
HKD1_k127_5567373_45 TIGRFAM amino acid adenylation domain - - - 0.0000001111 64.0
HKD1_k127_5567373_47 - - - - 0.0001591 47.0
HKD1_k127_5567373_48 Putative zinc-finger - - - 0.0001668 54.0
HKD1_k127_5567373_5 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 516.0
HKD1_k127_5567373_6 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 436.0
HKD1_k127_5567373_7 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 377.0
HKD1_k127_5567373_8 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 366.0
HKD1_k127_5567373_9 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 368.0
HKD1_k127_5568622_0 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 1.662e-259 830.0
HKD1_k127_5568622_1 alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 355.0
HKD1_k127_5607040_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.935e-200 632.0
HKD1_k127_5607040_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002027 280.0
HKD1_k127_5607040_2 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000001619 242.0
HKD1_k127_5607040_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000009327 237.0
HKD1_k127_5607040_4 Fibronectin type 3 domain - - - 0.0000000002234 74.0
HKD1_k127_5620651_0 PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 377.0
HKD1_k127_5620651_1 - - - - 0.0000000000000000000000000000000000006391 152.0
HKD1_k127_5620651_2 - - - - 0.000000000000000000000000000000000002347 151.0
HKD1_k127_5620651_3 Conserved hypothetical protein 698 - - - 0.000000000000000004005 86.0
HKD1_k127_5620651_4 Histidine kinase - - - 0.0000000000001184 78.0
HKD1_k127_5620651_6 Domain of unknown function (DUF4118) - - - 0.00000009391 60.0
HKD1_k127_5620651_7 - - - - 0.0000006997 61.0
HKD1_k127_5635417_0 Hep Hag repeat protein K19233,K21449 - - 0.000000000000000000000000000000001873 150.0
HKD1_k127_5635417_1 HD domain K07814 - - 0.000000000000000001324 95.0
HKD1_k127_5635417_3 amine dehydrogenase activity K07004,K20276 - - 0.0000000001179 75.0
HKD1_k127_5635417_4 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000006291 70.0
HKD1_k127_567507_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 432.0
HKD1_k127_567507_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000005404 260.0
HKD1_k127_567507_2 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 0.000000000000000000000000000000000000000000000000000000004385 201.0
HKD1_k127_5682498_0 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 595.0
HKD1_k127_5682498_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 512.0
HKD1_k127_5682498_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 361.0
HKD1_k127_5682498_11 Methyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 334.0
HKD1_k127_5682498_12 glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004581 270.0
HKD1_k127_5682498_13 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000002366 225.0
HKD1_k127_5682498_14 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000005772 214.0
HKD1_k127_5682498_15 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000001302 171.0
HKD1_k127_5682498_16 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000002586 179.0
HKD1_k127_5682498_17 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000001761 150.0
HKD1_k127_5682498_18 DUF218 domain - GO:0000270,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0030203,GO:0031224,GO:0042546,GO:0043164,GO:0043170,GO:0044085,GO:0044425,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901564 - 0.000000000000000002817 94.0
HKD1_k127_5682498_19 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000000000007323 76.0
HKD1_k127_5682498_2 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 483.0
HKD1_k127_5682498_20 PFAM DUF218 domain - - - 0.000000000002789 80.0
HKD1_k127_5682498_21 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000004836 78.0
HKD1_k127_5682498_22 Methyltransferase domain - - - 0.0000000002748 71.0
HKD1_k127_5682498_23 O-antigen polymerase K18814 - - 0.000000001149 72.0
HKD1_k127_5682498_24 PFAM glycosyl transferase family 39 - - - 0.0002354 54.0
HKD1_k127_5682498_3 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 502.0
HKD1_k127_5682498_4 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 432.0
HKD1_k127_5682498_5 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 395.0
HKD1_k127_5682498_6 Thiazole biosynthesis protein ThiG K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 375.0
HKD1_k127_5682498_7 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 366.0
HKD1_k127_5682498_8 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009272 368.0
HKD1_k127_5682498_9 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008647 355.0
HKD1_k127_5734548_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 503.0
HKD1_k127_5734548_1 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000002037 250.0
HKD1_k127_5734548_2 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000008587 211.0
HKD1_k127_5756992_0 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 466.0
HKD1_k127_5756992_1 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003812 264.0
HKD1_k127_5756992_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000002101 79.0
HKD1_k127_5756992_3 CarboxypepD_reg-like domain - - - 0.0000003608 63.0
HKD1_k127_5775572_0 COG1960 Acyl-CoA dehydrogenases K20035 - - 0.0000000000000000000000000000000000000000000000000000000003849 207.0
HKD1_k127_5775572_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000001153 199.0
HKD1_k127_5802531_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1242.0
HKD1_k127_5802531_1 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 2.138e-269 852.0
HKD1_k127_5802531_10 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002158 280.0
HKD1_k127_5802531_11 RibD C-terminal domain K00082,K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004173 280.0
HKD1_k127_5802531_12 Methyltransferase FkbM family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002901 263.0
HKD1_k127_5802531_13 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000004619 259.0
HKD1_k127_5802531_14 surface antigen variable number - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001031 283.0
HKD1_k127_5802531_15 6-pyruvoyl tetrahydropterin synthase - - - 0.000000000000000000000000000000000000000000000000000000000004345 211.0
HKD1_k127_5802531_16 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000001403 216.0
HKD1_k127_5802531_17 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.0000000000000000000000000000000000000000000000000000000002892 223.0
HKD1_k127_5802531_18 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000001055 185.0
HKD1_k127_5802531_19 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000009666 182.0
HKD1_k127_5802531_2 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.968e-200 629.0
HKD1_k127_5802531_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000007361 163.0
HKD1_k127_5802531_21 - - - - 0.00000000000000000000000000000000006767 149.0
HKD1_k127_5802531_22 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000202 134.0
HKD1_k127_5802531_23 Alpha/beta hydrolase family - - - 0.0000000000000000000000000001558 122.0
HKD1_k127_5802531_24 DinB family - - - 0.0000000000000000000000000007512 121.0
HKD1_k127_5802531_25 Alpha/beta hydrolase family - - - 0.0000000000000000000000000007718 123.0
HKD1_k127_5802531_26 Binds the 23S rRNA K02909 - - 0.000000000000000000000000006666 112.0
HKD1_k127_5802531_27 Biotin-requiring enzyme - - - 0.0000000000000000002221 94.0
HKD1_k127_5802531_28 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000001681 59.0
HKD1_k127_5802531_29 PFAM CAAX amino terminal protease family K07052 - - 0.0005168 51.0
HKD1_k127_5802531_3 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 417.0
HKD1_k127_5802531_4 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 404.0
HKD1_k127_5802531_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 417.0
HKD1_k127_5802531_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 355.0
HKD1_k127_5802531_7 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 330.0
HKD1_k127_5802531_8 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 316.0
HKD1_k127_5802531_9 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001694 310.0
HKD1_k127_5808785_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 456.0
HKD1_k127_5808785_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.000000000000000000000000000006516 120.0
HKD1_k127_5808785_2 - K00262 - 1.4.1.4 0.00000000000001271 73.0
HKD1_k127_581192_0 PQQ enzyme repeat - - - 4.147e-217 697.0
HKD1_k127_581192_1 PQQ enzyme repeat K00117 - 1.1.5.2 7.81e-201 647.0
HKD1_k127_581192_2 extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 332.0
HKD1_k127_581192_3 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007821 260.0
HKD1_k127_581192_4 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002831 254.0
HKD1_k127_581192_5 - - - - 0.00000000000000000000000000000000000001371 166.0
HKD1_k127_581192_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000006106 71.0
HKD1_k127_5932014_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1028.0
HKD1_k127_5932014_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.624e-286 900.0
HKD1_k127_5932014_10 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 417.0
HKD1_k127_5932014_11 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 389.0
HKD1_k127_5932014_12 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01919,K01955,K03802 - 6.3.2.2,6.3.2.29,6.3.2.30,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 387.0
HKD1_k127_5932014_13 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 368.0
HKD1_k127_5932014_14 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 377.0
HKD1_k127_5932014_15 carboxylic acid catabolic process K01856,K19802 - 5.1.1.20,5.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 314.0
HKD1_k127_5932014_16 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 301.0
HKD1_k127_5932014_17 Phosphoesterase family K21302 - 3.1.3.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001158 289.0
HKD1_k127_5932014_18 Spore coat protein CotH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000481 282.0
HKD1_k127_5932014_19 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001897 266.0
HKD1_k127_5932014_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.21e-243 771.0
HKD1_k127_5932014_20 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000004439 247.0
HKD1_k127_5932014_21 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000009418 241.0
HKD1_k127_5932014_22 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000001556 235.0
HKD1_k127_5932014_23 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000004271 232.0
HKD1_k127_5932014_24 Site-specific DNA-methyltransferase (adenine-specific) K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000001652 231.0
HKD1_k127_5932014_25 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000001661 230.0
HKD1_k127_5932014_26 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000004445 201.0
HKD1_k127_5932014_27 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000005297 205.0
HKD1_k127_5932014_28 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000000000000000000000000000000000002004 211.0
HKD1_k127_5932014_29 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000001295 196.0
HKD1_k127_5932014_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.067e-231 725.0
HKD1_k127_5932014_30 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000000000000000000000000000000001827 196.0
HKD1_k127_5932014_31 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000001866 165.0
HKD1_k127_5932014_32 MoaE protein K21142 - 2.8.1.12 0.00000000000000000000000000000000000000003873 157.0
HKD1_k127_5932014_33 Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000001944 151.0
HKD1_k127_5932014_34 Endoribonuclease L-PSP K09021,K09022 GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019740,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.99.10 0.000000000000000000000000000000000000008316 151.0
HKD1_k127_5932014_35 - - - - 0.000000000000000000000000000000000000305 155.0
HKD1_k127_5932014_36 Belongs to the Nudix hydrolase family K01515 - 3.6.1.13 0.000000000000000000000000000000000014 141.0
HKD1_k127_5932014_37 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000009846 140.0
HKD1_k127_5932014_38 protein maturation K13628 - - 0.000000000000000000000000000000001572 132.0
HKD1_k127_5932014_39 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000001676 146.0
HKD1_k127_5932014_4 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 604.0
HKD1_k127_5932014_40 protein-(glutamine-N5) methyltransferase activity - - - 0.00000000000000000000000000000002243 133.0
HKD1_k127_5932014_41 Trehalose utilisation - - - 0.000000000000000000000000000009592 124.0
HKD1_k127_5932014_42 Protein involved in formate dehydrogenase formation K02380 - - 0.0000000000000000000000001923 118.0
HKD1_k127_5932014_43 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000001372 113.0
HKD1_k127_5932014_44 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000001886 115.0
HKD1_k127_5932014_45 Belongs to the Fur family K03711 - - 0.00000000000000000000005676 112.0
HKD1_k127_5932014_46 - - - - 0.0000000000000000000004427 103.0
HKD1_k127_5932014_47 - - - - 0.000000000000000000003927 100.0
HKD1_k127_5932014_48 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000003612 88.0
HKD1_k127_5932014_49 Domain of unknown function (DUF4399) - - - 0.000000000000000001379 99.0
HKD1_k127_5932014_5 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 591.0
HKD1_k127_5932014_50 PFAM histidine triad (HIT) protein - - - 0.0000000000000001933 85.0
HKD1_k127_5932014_51 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000264 85.0
HKD1_k127_5932014_52 - - - - 0.000000000000001762 81.0
HKD1_k127_5932014_53 HAD-hyrolase-like K20862 - 3.1.3.102,3.1.3.104 0.000000000000001932 86.0
HKD1_k127_5932014_54 - - - - 0.00000000000002712 81.0
HKD1_k127_5932014_55 Cold shock protein domain - - - 0.0000000000006248 72.0
HKD1_k127_5932014_56 ABC transporter K02003 - - 0.000000000004937 78.0
HKD1_k127_5932014_57 PFAM molybdopterin biosynthesis MoaE protein K03635,K21142 - 2.8.1.12 0.00000000000673 74.0
HKD1_k127_5932014_58 Cold-shock protein K03704 - - 0.0000000001567 65.0
HKD1_k127_5932014_59 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0005784 51.0
HKD1_k127_5932014_6 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 561.0
HKD1_k127_5932014_60 Protein of unknown function (DUF1232) - - - 0.0009402 51.0
HKD1_k127_5932014_7 ATP dependent DNA ligase C terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 501.0
HKD1_k127_5932014_8 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 494.0
HKD1_k127_5932014_9 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 461.0
HKD1_k127_598441_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 1.186e-213 682.0
HKD1_k127_598441_1 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 421.0
HKD1_k127_598441_10 - - - - 0.00000000000000000000000000000000000008185 154.0
HKD1_k127_598441_11 PAP2 superfamily - - - 0.0000000000000000000000000000000000001517 153.0
HKD1_k127_598441_12 - - - - 0.000000000000000000000000000000000001472 154.0
HKD1_k127_598441_13 - - - - 0.00000000000000000000000001702 123.0
HKD1_k127_598441_14 - K02172 - - 0.0000000000000000000000002253 116.0
HKD1_k127_598441_15 - - - - 0.0000000000000000000000005965 115.0
HKD1_k127_598441_16 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000001342 91.0
HKD1_k127_598441_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000001388 76.0
HKD1_k127_598441_18 - - - - 0.00000000001777 76.0
HKD1_k127_598441_19 - - - - 0.00000003335 66.0
HKD1_k127_598441_2 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 314.0
HKD1_k127_598441_20 dihydroorotate dehydrogenase activity - - - 0.00001395 55.0
HKD1_k127_598441_3 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000000000000000000000000004022 225.0
HKD1_k127_598441_4 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000000000000000000000002594 225.0
HKD1_k127_598441_5 - - - - 0.0000000000000000000000000000000000000000000000000001113 196.0
HKD1_k127_598441_6 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000005207 207.0
HKD1_k127_598441_7 - - - - 0.0000000000000000000000000000000000000000000002652 173.0
HKD1_k127_598441_8 - - - - 0.00000000000000000000000000000000000000000003924 168.0
HKD1_k127_598441_9 amidohydrolase - - - 0.00000000000000000000000000000000000000009378 169.0
HKD1_k127_599279_0 COG1404 Subtilisin-like serine proteases K14645 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000001193 237.0
HKD1_k127_599279_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000007236 187.0
HKD1_k127_6006922_0 gluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 481.0
HKD1_k127_6006922_1 polysaccharide catabolic process K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 414.0
HKD1_k127_6006922_10 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002319 272.0
HKD1_k127_6006922_11 thioesterase involved in non-ribosomal peptide biosynthesis K01071 - 3.1.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000003638 247.0
HKD1_k127_6006922_12 PFAM Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000007244 239.0
HKD1_k127_6006922_13 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000001079 231.0
HKD1_k127_6006922_14 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000000000000000000001446 218.0
HKD1_k127_6006922_15 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000003504 205.0
HKD1_k127_6006922_16 - - - - 0.00000000000000000000000000000000000000000000000323 199.0
HKD1_k127_6006922_17 Sulfotransferase - - - 0.0000000000000000000000000000000000000000000002327 181.0
HKD1_k127_6006922_18 Methyltransferase domain - - - 0.000000000000000000000000000000000003896 153.0
HKD1_k127_6006922_19 MbtH-like protein K05375 - - 0.0000000000000000000000000145 121.0
HKD1_k127_6006922_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 399.0
HKD1_k127_6006922_20 guanyl-nucleotide exchange factor activity K20276 - - 0.0000000000000000000000002799 124.0
HKD1_k127_6006922_21 - - - - 0.00000000000000000004265 106.0
HKD1_k127_6006922_22 dextransucrase activity - - - 0.000000000000000002937 87.0
HKD1_k127_6006922_23 Peptidase family M23 - - - 0.000000000000004194 91.0
HKD1_k127_6006922_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 343.0
HKD1_k127_6006922_4 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 334.0
HKD1_k127_6006922_5 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 307.0
HKD1_k127_6006922_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007828 277.0
HKD1_k127_6006922_7 polygalacturonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001041 296.0
HKD1_k127_6006922_8 Belongs to the glycosyl hydrolase 32 family K00692 - 2.4.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000005729 288.0
HKD1_k127_6006922_9 dextransucrase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008917 287.0
HKD1_k127_6038930_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.812e-209 657.0
HKD1_k127_6038930_1 Two component transcriptional regulator, winged helix family K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000001477 229.0
HKD1_k127_6059224_0 Dehydrogenase K00117 - 1.1.5.2 7.541e-294 915.0
HKD1_k127_6059224_1 - - - - 2.221e-280 884.0
HKD1_k127_6059224_10 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000001036 217.0
HKD1_k127_6059224_11 - - - - 0.0000000000000000000000000000000000000000000002967 179.0
HKD1_k127_6059224_12 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000000000000000006098 146.0
HKD1_k127_6059224_13 RES - - - 0.00000000000000000000000000000000003577 147.0
HKD1_k127_6059224_14 - - - - 0.0000000000000000000000000000000002292 147.0
HKD1_k127_6059224_15 Belongs to the peptidase S8 family K14645,K20276 - - 0.000000000000000000000008404 114.0
HKD1_k127_6059224_16 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000001235 114.0
HKD1_k127_6059224_17 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000003404 80.0
HKD1_k127_6059224_2 repeat protein - - - 1.314e-206 653.0
HKD1_k127_6059224_20 Common central domain of tyrosinase - - - 0.0000007089 57.0
HKD1_k127_6059224_3 L-lactate dehydrogenase K00101,K16422 - 1.1.2.3,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 463.0
HKD1_k127_6059224_4 Common central domain of tyrosinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 433.0
HKD1_k127_6059224_5 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 428.0
HKD1_k127_6059224_6 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 314.0
HKD1_k127_6059224_7 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 334.0
HKD1_k127_6059224_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 308.0
HKD1_k127_6059224_9 oxidoreductase activity K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009883 283.0
HKD1_k127_6059938_0 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 442.0
HKD1_k127_6059938_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 360.0
HKD1_k127_6059938_10 YjbR - - - 0.00000182 59.0
HKD1_k127_6059938_11 YjbR - - - 0.0002841 48.0
HKD1_k127_6059938_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009612 349.0
HKD1_k127_6059938_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 303.0
HKD1_k127_6059938_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004212 273.0
HKD1_k127_6059938_5 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000001079 287.0
HKD1_k127_6059938_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008737 262.0
HKD1_k127_6059938_7 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000004878 219.0
HKD1_k127_6059938_8 - - - - 0.0000000000000000000000000000000000000000000001419 179.0
HKD1_k127_6059938_9 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000007567 149.0
HKD1_k127_6064436_0 Putative peptidoglycan binding domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 328.0
HKD1_k127_6064436_1 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 293.0
HKD1_k127_6064436_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000001738 223.0
HKD1_k127_6064436_3 FCD - - - 0.00000000000000000000000000000000000000000000000000000002308 205.0
HKD1_k127_6064436_4 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000244 187.0
HKD1_k127_6064436_5 Amino acid permease - - - 0.0000000000000000000000000000000000000008578 154.0
HKD1_k127_6064436_6 - - - - 0.0000000000000000000000000003257 133.0
HKD1_k127_6064436_7 PFAM TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000007293 132.0
HKD1_k127_6064436_8 Cbs domain K04767 - - 0.0000000000000000000004723 104.0
HKD1_k127_6121030_0 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000006681 195.0
HKD1_k127_6121030_1 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000003275 161.0
HKD1_k127_612519_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 501.0
HKD1_k127_612519_1 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000008309 162.0
HKD1_k127_612519_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000006464 147.0
HKD1_k127_6193794_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1521.0
HKD1_k127_6193794_1 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0 1187.0
HKD1_k127_6193794_10 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000003881 250.0
HKD1_k127_6193794_11 ABC transporter K02049,K15578,K15579 - - 0.000000000000000000000000000000000000000000000000000000000000000001933 237.0
HKD1_k127_6193794_12 Nitrogen regulatory protein P-II K04751,K04752 - - 0.00000000000000000000000000000000000000004473 155.0
HKD1_k127_6193794_13 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.000000000000000000000001981 119.0
HKD1_k127_6193794_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1045.0
HKD1_k127_6193794_3 molybdopterin cofactor binding K00372 - - 6.83e-266 836.0
HKD1_k127_6193794_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051,K15576,K22067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 559.0
HKD1_k127_6193794_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 504.0
HKD1_k127_6193794_6 Nitrate nitrite transporter K02575 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008351 409.0
HKD1_k127_6193794_7 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 336.0
HKD1_k127_6193794_8 COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 347.0
HKD1_k127_6193794_9 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002484 271.0
HKD1_k127_619687_0 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 389.0
HKD1_k127_619687_1 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 338.0
HKD1_k127_619687_2 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 338.0
HKD1_k127_619687_3 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000135 261.0
HKD1_k127_619687_4 cellulase activity - - - 0.00000000000000000000000000000000000000000000000017 203.0
HKD1_k127_619687_5 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000934 167.0
HKD1_k127_6200656_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1211.0
HKD1_k127_6200656_1 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 4.115e-259 843.0
HKD1_k127_6200656_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000028 175.0
HKD1_k127_6200656_11 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000002673 130.0
HKD1_k127_6200656_12 acr, cog1993 K09137 - - 0.00000000000000000000000000009967 134.0
HKD1_k127_6200656_13 Glycoprotease K14742 - - 0.0000000000000000000003092 105.0
HKD1_k127_6200656_14 Tetratricopeptide repeat - - - 0.00000499 57.0
HKD1_k127_6200656_15 regulation of response to stimulus K01347,K20276 - 3.4.21.72 0.0003186 52.0
HKD1_k127_6200656_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 4.56e-254 797.0
HKD1_k127_6200656_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 411.0
HKD1_k127_6200656_4 PFAM Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004002 291.0
HKD1_k127_6200656_5 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 266.0
HKD1_k127_6200656_6 Histidine kinase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000001632 205.0
HKD1_k127_6200656_7 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000000000000000000000002051 198.0
HKD1_k127_6200656_8 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000001249 197.0
HKD1_k127_6200656_9 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000006696 193.0
HKD1_k127_6205781_0 Cytochrome c K02305,K07152 - - 0.0000000000000283 82.0
HKD1_k127_6205781_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000006241 83.0
HKD1_k127_6205781_2 amine dehydrogenase activity - - - 0.0000000002107 69.0
HKD1_k127_6229837_0 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 411.0
HKD1_k127_6229837_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000004527 263.0
HKD1_k127_6229837_2 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.0000000000000000000000000000000000000000000000000000635 193.0
HKD1_k127_6236510_0 Polysulphide reductase, NrfD K00185 - - 1.796e-225 707.0
HKD1_k127_6236510_1 PFAM 4Fe-4S K00184,K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 467.0
HKD1_k127_6236510_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 370.0
HKD1_k127_6236510_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001312 251.0
HKD1_k127_6236510_4 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000005292 234.0
HKD1_k127_6236510_5 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000003426 163.0
HKD1_k127_6236510_6 - - - - 0.000000000000007993 88.0
HKD1_k127_6240308_0 Dehydrogenase K00117 - 1.1.5.2 7.276e-289 900.0
HKD1_k127_6240308_1 PFAM ABC transporter - - - 8.901e-286 890.0
HKD1_k127_6240308_10 Ferredoxin--NADP reductase K21567 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000001392 128.0
HKD1_k127_6240308_11 - - - - 0.00000000000000000000000001832 121.0
HKD1_k127_6240308_12 Cupredoxin-like domain - - - 0.00007225 51.0
HKD1_k127_6240308_2 DNA helicase K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 479.0
HKD1_k127_6240308_3 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 449.0
HKD1_k127_6240308_4 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 393.0
HKD1_k127_6240308_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 329.0
HKD1_k127_6240308_6 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001292 243.0
HKD1_k127_6240308_7 BlaR1 peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000003653 229.0
HKD1_k127_6240308_8 Penicillinase repressor - - - 0.000000000000000000000000000000000001701 154.0
HKD1_k127_6240308_9 - - - - 0.00000000000000000000000000003869 128.0
HKD1_k127_62693_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1193.0
HKD1_k127_62693_1 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 9.388e-229 719.0
HKD1_k127_62693_10 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 359.0
HKD1_k127_62693_11 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 361.0
HKD1_k127_62693_12 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 349.0
HKD1_k127_62693_13 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 334.0
HKD1_k127_62693_14 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 325.0
HKD1_k127_62693_15 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 344.0
HKD1_k127_62693_16 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 301.0
HKD1_k127_62693_17 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 304.0
HKD1_k127_62693_18 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 306.0
HKD1_k127_62693_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005011 304.0
HKD1_k127_62693_2 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 507.0
HKD1_k127_62693_20 PFAM peptidase K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000001181 280.0
HKD1_k127_62693_21 PFAM Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009937 276.0
HKD1_k127_62693_22 COG0210 Superfamily I DNA and RNA helicases K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000166 241.0
HKD1_k127_62693_23 Belongs to the DapB family K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000001444 211.0
HKD1_k127_62693_24 membrane - - - 0.000000000000000000000000000000000000000000000000000000001368 210.0
HKD1_k127_62693_25 decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000005937 204.0
HKD1_k127_62693_26 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000000000000000001518 159.0
HKD1_k127_62693_27 O-methyltransferase - - - 0.00000000000000000000000000000000000000002272 162.0
HKD1_k127_62693_28 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000001269 157.0
HKD1_k127_62693_3 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 452.0
HKD1_k127_62693_30 - - - - 0.00000000000000000000000001779 120.0
HKD1_k127_62693_31 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000006998 117.0
HKD1_k127_62693_32 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000001268 106.0
HKD1_k127_62693_33 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000001838 109.0
HKD1_k127_62693_34 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.000000000000007198 90.0
HKD1_k127_62693_35 Putative MetA-pathway of phenol degradation - - - 0.000000000003221 78.0
HKD1_k127_62693_36 - - - - 0.0000000002041 73.0
HKD1_k127_62693_37 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000002302 55.0
HKD1_k127_62693_38 - - - - 0.0003354 48.0
HKD1_k127_62693_39 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0007259 45.0
HKD1_k127_62693_4 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 443.0
HKD1_k127_62693_40 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0009772 47.0
HKD1_k127_62693_5 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 408.0
HKD1_k127_62693_6 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 393.0
HKD1_k127_62693_7 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 394.0
HKD1_k127_62693_8 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 377.0
HKD1_k127_62693_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 366.0
HKD1_k127_6327780_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 1.603e-294 919.0
HKD1_k127_6327780_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 1.983e-281 872.0
HKD1_k127_6327780_10 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 490.0
HKD1_k127_6327780_101 - - - - 0.00000000001244 76.0
HKD1_k127_6327780_102 - - - - 0.00000000002739 74.0
HKD1_k127_6327780_103 - - - - 0.0000000007434 72.0
HKD1_k127_6327780_104 - - - - 0.000000001042 69.0
HKD1_k127_6327780_106 Psort location CytoplasmicMembrane, score K09153 - - 0.000000002956 64.0
HKD1_k127_6327780_107 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000217 51.0
HKD1_k127_6327780_108 PFAM PEGA domain - - - 0.000003709 58.0
HKD1_k127_6327780_109 PFAM VanZ family protein - - - 0.000003874 59.0
HKD1_k127_6327780_11 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006718 487.0
HKD1_k127_6327780_111 - - - - 0.0002518 51.0
HKD1_k127_6327780_112 PFAM von Willebrand factor type A K07114 - - 0.0002847 51.0
HKD1_k127_6327780_12 N,N-dimethylaniline monooxygenase activity K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 459.0
HKD1_k127_6327780_13 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 451.0
HKD1_k127_6327780_14 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 455.0
HKD1_k127_6327780_15 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 465.0
HKD1_k127_6327780_16 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 459.0
HKD1_k127_6327780_17 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 437.0
HKD1_k127_6327780_18 Belongs to the glutaminase family K01425 - 3.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 413.0
HKD1_k127_6327780_19 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 427.0
HKD1_k127_6327780_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.998e-271 847.0
HKD1_k127_6327780_20 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 398.0
HKD1_k127_6327780_21 glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 378.0
HKD1_k127_6327780_22 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 385.0
HKD1_k127_6327780_23 TIGRFAM FemAB-related protein, PEP-CTERM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 353.0
HKD1_k127_6327780_24 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 365.0
HKD1_k127_6327780_25 PFAM Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 338.0
HKD1_k127_6327780_26 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 338.0
HKD1_k127_6327780_27 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 340.0
HKD1_k127_6327780_28 xylanase chitin deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 325.0
HKD1_k127_6327780_29 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 316.0
HKD1_k127_6327780_3 1,4-alpha-glucan branching enzyme K00700,K01236 - 2.4.1.18,3.2.1.141 5.028e-229 723.0
HKD1_k127_6327780_30 teichoic acid transport K01990,K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 311.0
HKD1_k127_6327780_31 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 309.0
HKD1_k127_6327780_32 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005316 277.0
HKD1_k127_6327780_33 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001629 291.0
HKD1_k127_6327780_34 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000022 272.0
HKD1_k127_6327780_35 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004189 284.0
HKD1_k127_6327780_36 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001058 268.0
HKD1_k127_6327780_37 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001977 267.0
HKD1_k127_6327780_38 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001047 258.0
HKD1_k127_6327780_39 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001259 271.0
HKD1_k127_6327780_4 COG1680 Beta-lactamase class C and other penicillin binding - - - 1.133e-217 707.0
HKD1_k127_6327780_40 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006092 267.0
HKD1_k127_6327780_41 Lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009668 267.0
HKD1_k127_6327780_42 Domain of unknown function (DUF5009) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001035 253.0
HKD1_k127_6327780_43 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006029 250.0
HKD1_k127_6327780_44 transcriptional regulator K11914 GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000001037 246.0
HKD1_k127_6327780_45 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004296 254.0
HKD1_k127_6327780_46 Methyltransferase domain K05303 - - 0.0000000000000000000000000000000000000000000000000000000000000000004605 236.0
HKD1_k127_6327780_47 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000003697 235.0
HKD1_k127_6327780_48 involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000009961 228.0
HKD1_k127_6327780_49 Macrocin-O-methyltransferase (TylF) - - - 0.0000000000000000000000000000000000000000000000000000000000000005061 228.0
HKD1_k127_6327780_5 - - - - 1.67e-214 698.0
HKD1_k127_6327780_50 - - - - 0.0000000000000000000000000000000000000000000000000000000000000008533 250.0
HKD1_k127_6327780_51 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000001643 224.0
HKD1_k127_6327780_52 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000004718 225.0
HKD1_k127_6327780_53 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000000000000000000000000000008566 226.0
HKD1_k127_6327780_54 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000003598 218.0
HKD1_k127_6327780_55 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000004348 211.0
HKD1_k127_6327780_56 Sugar transferase, PEP-CTERM EpsH1 system associated - - - 0.0000000000000000000000000000000000000000000000000000000002284 219.0
HKD1_k127_6327780_57 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000005378 210.0
HKD1_k127_6327780_58 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000015 216.0
HKD1_k127_6327780_59 - - - - 0.00000000000000000000000000000000000000000000000000000007772 206.0
HKD1_k127_6327780_6 COG4993 Glucose dehydrogenase - - - 6.403e-199 649.0
HKD1_k127_6327780_60 - - - - 0.0000000000000000000000000000000000000000000000000000004258 213.0
HKD1_k127_6327780_61 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000002856 206.0
HKD1_k127_6327780_62 maltose O-acetyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000009598 204.0
HKD1_k127_6327780_63 TIR domain - - - 0.0000000000000000000000000000000000000000000000000009303 195.0
HKD1_k127_6327780_64 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000329 202.0
HKD1_k127_6327780_65 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000002349 189.0
HKD1_k127_6327780_66 -O-antigen - - - 0.00000000000000000000000000000000000000000000000003205 196.0
HKD1_k127_6327780_67 Maleate cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000005217 185.0
HKD1_k127_6327780_68 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000002228 190.0
HKD1_k127_6327780_69 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - 0.000000000000000000000000000000000000000000000003074 182.0
HKD1_k127_6327780_7 Animal haem peroxidase - - - 2.942e-198 631.0
HKD1_k127_6327780_70 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000001176 175.0
HKD1_k127_6327780_71 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000003944 181.0
HKD1_k127_6327780_72 - - - - 0.0000000000000000000000000000000000000000000005033 192.0
HKD1_k127_6327780_73 Belongs to the globin family - - - 0.000000000000000000000000000000000000000000002794 169.0
HKD1_k127_6327780_74 Transport permease protein K09688,K09690 - - 0.00000000000000000000000000000000000000000001079 174.0
HKD1_k127_6327780_75 transcriptional regulator K13652,K13653 - - 0.00000000000000000000000000000000000000000006925 168.0
HKD1_k127_6327780_76 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000002358 169.0
HKD1_k127_6327780_77 - - - - 0.0000000000000000000000000000000000000000143 166.0
HKD1_k127_6327780_78 - - - - 0.0000000000000000000000000000000000000003459 162.0
HKD1_k127_6327780_79 TIGRFAM EpsI family protein - - - 0.00000000000000000000000000000000000001773 153.0
HKD1_k127_6327780_8 Cyclic nucleotide-monophosphate binding domain - - - 1.365e-197 627.0
HKD1_k127_6327780_80 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000002287 154.0
HKD1_k127_6327780_81 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000001854 155.0
HKD1_k127_6327780_82 methyltransferase - - - 0.000000000000000000000000000000000005758 148.0
HKD1_k127_6327780_83 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000005844 147.0
HKD1_k127_6327780_84 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000000000002616 147.0
HKD1_k127_6327780_85 - - - - 0.0000000000000000000000000000000001073 146.0
HKD1_k127_6327780_86 AAA domain K08252 - 2.7.10.1 0.0000000000000000000000000000000003528 145.0
HKD1_k127_6327780_87 helix-turn-helix- domain containing protein, AraC type K13653 - - 0.000000000000000000000000000000001944 141.0
HKD1_k127_6327780_88 - - - - 0.0000000000000000000000000000004225 137.0
HKD1_k127_6327780_89 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000001833 134.0
HKD1_k127_6327780_9 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 492.0
HKD1_k127_6327780_90 - - - - 0.000000000000000000000000000423 133.0
HKD1_k127_6327780_91 hyperosmotic response - - - 0.00000000000000000000000002688 121.0
HKD1_k127_6327780_92 - - - - 0.0000000000000000000001679 110.0
HKD1_k127_6327780_93 Amidohydrolase family - - - 0.000000000000000000005041 106.0
HKD1_k127_6327780_94 - - - - 0.000000000000000000179 102.0
HKD1_k127_6327780_95 - - - - 0.0000000000000000005342 90.0
HKD1_k127_6327780_96 Globin - - - 0.000000000000000001569 91.0
HKD1_k127_6327780_97 - - - - 0.0000000000000005566 83.0
HKD1_k127_6327780_99 23S rRNA-intervening sequence protein - - - 0.0000000000002009 77.0
HKD1_k127_6346153_0 Radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 598.0
HKD1_k127_6346153_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 480.0
HKD1_k127_6346153_10 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0003502 49.0
HKD1_k127_6346153_2 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 296.0
HKD1_k127_6346153_3 sulphate transporter - - - 0.00000000000000000000000000000000000000000000000000611 186.0
HKD1_k127_6346153_4 - - - - 0.00000000000000000000000000000000000000000000221 173.0
HKD1_k127_6346153_5 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000005811 136.0
HKD1_k127_6346153_6 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000006802 131.0
HKD1_k127_6346153_7 COG4635 Flavodoxin K00230 - 1.3.5.3 0.00000000000000000000000000007245 126.0
HKD1_k127_6346153_8 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000003761 99.0
HKD1_k127_6346153_9 - - - - 0.00002612 55.0
HKD1_k127_6347142_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3 2.607e-198 649.0
HKD1_k127_6401341_0 Glycogen debranching enzyme - - - 0.0 1411.0
HKD1_k127_6401341_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 417.0
HKD1_k127_6401341_11 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000008569 66.0
HKD1_k127_6401341_12 - - - - 0.00001084 56.0
HKD1_k127_6401341_2 Histidine kinase K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 304.0
HKD1_k127_6401341_3 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005232 273.0
HKD1_k127_6401341_4 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002896 231.0
HKD1_k127_6401341_5 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000004706 241.0
HKD1_k127_6401341_6 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000006357 130.0
HKD1_k127_6401341_7 cheY-homologous receiver domain - - - 0.000000000000000000000000003116 115.0
HKD1_k127_6401341_8 AraC-binding-like domain - - - 0.0000000000000001467 84.0
HKD1_k127_6401341_9 Tfp pilus assembly protein FimV - - - 0.0000000000001796 81.0
HKD1_k127_6419705_0 Lon protease (S16) C-terminal proteolytic domain K01338 - 3.4.21.53 0.0 1096.0
HKD1_k127_6419705_1 membrane K07027,K14205 - 2.3.2.3 9.896e-253 805.0
HKD1_k127_6419705_10 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 383.0
HKD1_k127_6419705_11 carboxylic ester hydrolase activity K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 386.0
HKD1_k127_6419705_12 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 329.0
HKD1_k127_6419705_13 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 332.0
HKD1_k127_6419705_14 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 290.0
HKD1_k127_6419705_15 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000946 284.0
HKD1_k127_6419705_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001874 275.0
HKD1_k127_6419705_17 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003172 284.0
HKD1_k127_6419705_18 Bacterial extracellular solute-binding proteins, family 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004495 240.0
HKD1_k127_6419705_19 Alg9-like mannosyltransferase family K05286 - - 0.0000000000000000000000000000000000000000000000000000000000000003985 239.0
HKD1_k127_6419705_2 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 9.278e-200 639.0
HKD1_k127_6419705_20 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000003355 244.0
HKD1_k127_6419705_21 ankyrin repeat K15503 - - 0.0000000000000000000000000000000000000000000000000000000000002467 233.0
HKD1_k127_6419705_22 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000009258 233.0
HKD1_k127_6419705_23 - - - - 0.00000000000000000000000000000000000000000000000000000002106 212.0
HKD1_k127_6419705_24 - - - - 0.00000000000000000000000000000000000000000000000000002122 201.0
HKD1_k127_6419705_25 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.000000000000000000000000000000000000005817 160.0
HKD1_k127_6419705_26 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000007407 151.0
HKD1_k127_6419705_27 - - - - 0.00000000000000000000000000000000002057 149.0
HKD1_k127_6419705_28 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000001297 147.0
HKD1_k127_6419705_29 - - - - 0.000000000000000000000000000000000514 135.0
HKD1_k127_6419705_3 DNA topological change - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 603.0
HKD1_k127_6419705_30 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000003204 147.0
HKD1_k127_6419705_31 - - - - 0.00000000000000000000000000006553 128.0
HKD1_k127_6419705_32 Outer membrane efflux protein - - - 0.000000000000000000000000001187 129.0
HKD1_k127_6419705_33 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000005213 107.0
HKD1_k127_6419705_34 - - - - 0.0000000000000000000004638 106.0
HKD1_k127_6419705_35 Cupin 2, conserved barrel domain protein - - - 0.0000000000008182 74.0
HKD1_k127_6419705_36 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000001869 67.0
HKD1_k127_6419705_37 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000002412 62.0
HKD1_k127_6419705_38 - - - - 0.00002395 55.0
HKD1_k127_6419705_4 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 598.0
HKD1_k127_6419705_5 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 503.0
HKD1_k127_6419705_6 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 473.0
HKD1_k127_6419705_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 465.0
HKD1_k127_6419705_8 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 420.0
HKD1_k127_6419705_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 425.0
HKD1_k127_6432539_0 MacB-like periplasmic core domain - - - 9.67e-270 862.0
HKD1_k127_6432539_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.021e-210 670.0
HKD1_k127_6432539_10 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000000005013 192.0
HKD1_k127_6432539_11 - - - - 0.00000000000000000000000000000000000000000000004732 190.0
HKD1_k127_6432539_12 Histidine kinase K02668,K07709,K07710 - 2.7.13.3 0.0000000000000000000000000000000000000002975 165.0
HKD1_k127_6432539_13 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000001992 163.0
HKD1_k127_6432539_14 OmpA family K03640 - - 0.0000000000000000000006602 108.0
HKD1_k127_6432539_15 Thioredoxin - - - 0.00000000000000002074 95.0
HKD1_k127_6432539_16 protein N-acetylglucosaminyltransferase activity - - - 0.000005039 57.0
HKD1_k127_6432539_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 1.323e-197 628.0
HKD1_k127_6432539_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 485.0
HKD1_k127_6432539_4 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 462.0
HKD1_k127_6432539_5 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 301.0
HKD1_k127_6432539_6 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 320.0
HKD1_k127_6432539_7 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002136 247.0
HKD1_k127_6432539_8 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000001101 234.0
HKD1_k127_6432539_9 - - - - 0.000000000000000000000000000000000000000000000000000000002314 212.0
HKD1_k127_646847_0 Amidohydrolase family - - - 4.886e-199 634.0
HKD1_k127_646847_1 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 598.0
HKD1_k127_646847_10 DinB family - - - 0.0000000000000000000000000000000000000000000000000000005308 198.0
HKD1_k127_646847_11 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000000000000000009673 180.0
HKD1_k127_646847_12 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.0000000000000000000000000000000000000000000002534 184.0
HKD1_k127_646847_13 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000000000000002162 166.0
HKD1_k127_646847_14 DinB family - - - 0.00000000000000000000000000000000000000341 160.0
HKD1_k127_646847_15 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000007185 120.0
HKD1_k127_646847_16 - - - - 0.00000000000000000000000001408 121.0
HKD1_k127_646847_17 Methyltransferase - - - 0.000000000000000000009335 102.0
HKD1_k127_646847_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 405.0
HKD1_k127_646847_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 306.0
HKD1_k127_646847_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 308.0
HKD1_k127_646847_5 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 321.0
HKD1_k127_646847_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006734 291.0
HKD1_k127_646847_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005565 262.0
HKD1_k127_646847_8 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.000000000000000000000000000000000000000000000000000000000000005866 224.0
HKD1_k127_646847_9 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000002234 218.0
HKD1_k127_6493447_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.15e-248 773.0
HKD1_k127_6493447_1 Homospermidine synthase K00808 - 2.5.1.44 6.619e-231 724.0
HKD1_k127_6493447_10 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003111 278.0
HKD1_k127_6493447_11 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000148 267.0
HKD1_k127_6493447_12 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000002695 160.0
HKD1_k127_6493447_13 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000001359 136.0
HKD1_k127_6493447_14 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.000000000000000000000000000004125 138.0
HKD1_k127_6493447_16 Protein of unknown function VcgC/VcgE (DUF2780) - - - 0.0000000000000001339 92.0
HKD1_k127_6493447_17 carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000003071 81.0
HKD1_k127_6493447_18 Domain of unknown function (DUF1992) - - - 0.00000000000003221 87.0
HKD1_k127_6493447_19 - - - - 0.0000000000001428 81.0
HKD1_k127_6493447_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 1.21e-210 660.0
HKD1_k127_6493447_20 Glyoxalase-like domain - - - 0.00001985 56.0
HKD1_k127_6493447_21 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00002588 57.0
HKD1_k127_6493447_22 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00004946 55.0
HKD1_k127_6493447_3 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 1.686e-199 629.0
HKD1_k127_6493447_4 Saccharopine dehydrogenase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 563.0
HKD1_k127_6493447_5 PFAM Orn DAP Arg decarboxylase 2 K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 554.0
HKD1_k127_6493447_6 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 573.0
HKD1_k127_6493447_7 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 543.0
HKD1_k127_6493447_8 Amino acid kinase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 515.0
HKD1_k127_6493447_9 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 324.0
HKD1_k127_6534715_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 4.04e-278 871.0
HKD1_k127_6534715_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 349.0
HKD1_k127_6534715_2 Peptidase, M16 K07263 - - 0.000000000000000000000000000001171 133.0
HKD1_k127_6668157_0 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 458.0
HKD1_k127_6668157_1 - - - - 0.00000000000000000000000000000000000000001105 161.0
HKD1_k127_6750014_0 PQQ enzyme repeat K00117 - 1.1.5.2 4.362e-200 645.0
HKD1_k127_6750014_1 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 499.0
HKD1_k127_6750014_10 Transposase K07486 - - 0.00001661 47.0
HKD1_k127_6750014_2 cytochrome K17230 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 409.0
HKD1_k127_6750014_3 TIGRFAM polyphosphate nucleotide phosphotransferase, PPK2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 319.0
HKD1_k127_6750014_5 Thermolysin metallopeptidase, alpha-helical domain K01400,K08777 GO:0005575,GO:0005576 3.4.24.28 0.00000000000000000000000000000000000000000000000000000000000000000000008965 261.0
HKD1_k127_6750014_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000008314 217.0
HKD1_k127_6750014_7 decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000837 173.0
HKD1_k127_6750014_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000004159 71.0
HKD1_k127_6890059_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 4.934e-202 646.0
HKD1_k127_6890059_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 367.0
HKD1_k127_6890059_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.00000000000000000000000000000000000000000000000000000001548 222.0
HKD1_k127_6890059_3 recA bacterial DNA recombination protein - - - 0.00000000000000000000000000000002714 134.0
HKD1_k127_692515_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000194 248.0
HKD1_k127_692515_1 Domain of unknown function (DUF4383) - - - 0.0000000000000000002645 97.0
HKD1_k127_692515_2 COG0526 Thiol-disulfide isomerase and thioredoxins K00384 - 1.8.1.9 0.00000000002448 68.0
HKD1_k127_6928003_0 antibiotic catabolic process K13277,K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001246 269.0
HKD1_k127_6928003_1 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002588 245.0
HKD1_k127_6928003_2 - - - - 0.000000000000000000000000009895 123.0
HKD1_k127_6928003_3 - - - - 0.0000000000000009889 90.0
HKD1_k127_6928003_4 alpha/beta hydrolase fold - - - 0.00000002186 59.0
HKD1_k127_6928003_5 NmrA-like family - - - 0.000006884 49.0
HKD1_k127_7049531_0 MacB-like periplasmic core domain - - - 1.275e-321 1004.0
HKD1_k127_7049531_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 310.0
HKD1_k127_7049531_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000001494 192.0
HKD1_k127_7049531_3 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000006302 176.0
HKD1_k127_7049531_4 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000008022 139.0
HKD1_k127_7049531_5 - - - - 0.0000001102 58.0
HKD1_k127_7049531_6 Activator of Hsp90 ATPase 1 family protein - - - 0.000003122 60.0
HKD1_k127_7054199_0 Tripartite tricarboxylate transporter TctA family - - - 3.488e-248 781.0
HKD1_k127_7054199_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 436.0
HKD1_k127_7054199_2 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 312.0
HKD1_k127_7054199_3 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003572 251.0
HKD1_k127_7054199_4 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000003205 155.0
HKD1_k127_7055224_0 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.000000000000000000000000000000000000000000000000000000000000000000000000009996 270.0
HKD1_k127_7055224_1 cheY-homologous receiver domain K07658 - - 0.000000000000000000000003662 107.0
HKD1_k127_7055224_2 Oxidoreductase FAD-binding domain K17995 - 1.12.98.4 0.0000004719 53.0
HKD1_k127_7065605_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 1.795e-217 687.0
HKD1_k127_7065605_1 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 569.0
HKD1_k127_7065605_10 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 354.0
HKD1_k127_7065605_11 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 328.0
HKD1_k127_7065605_12 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 314.0
HKD1_k127_7065605_13 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002847 284.0
HKD1_k127_7065605_14 Lytic murein transglycosylase K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007528 252.0
HKD1_k127_7065605_15 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000001015 216.0
HKD1_k127_7065605_16 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000002721 212.0
HKD1_k127_7065605_17 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000001643 214.0
HKD1_k127_7065605_18 - - - - 0.000000000000000000000000000000000000000000000002845 181.0
HKD1_k127_7065605_19 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000001089 136.0
HKD1_k127_7065605_2 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 496.0
HKD1_k127_7065605_20 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000001443 143.0
HKD1_k127_7065605_21 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000001689 142.0
HKD1_k127_7065605_22 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000002108 118.0
HKD1_k127_7065605_23 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000007638 115.0
HKD1_k127_7065605_24 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000002326 124.0
HKD1_k127_7065605_25 23S rRNA-intervening sequence protein - - - 0.00000000000000000000007801 105.0
HKD1_k127_7065605_26 - - - - 0.000000000000000002002 89.0
HKD1_k127_7065605_27 AAA ATPase domain - - - 0.00000000000006301 83.0
HKD1_k127_7065605_28 Transcriptional regulator PadR-like family - - - 0.00003176 53.0
HKD1_k127_7065605_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 462.0
HKD1_k127_7065605_4 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 451.0
HKD1_k127_7065605_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 479.0
HKD1_k127_7065605_6 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 381.0
HKD1_k127_7065605_7 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 362.0
HKD1_k127_7065605_8 imidazolonepropionase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 340.0
HKD1_k127_7065605_9 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 338.0
HKD1_k127_7070615_0 PFAM Sulfatase - - - 2.093e-234 735.0
HKD1_k127_7070615_1 DNA topological change K03168 - 5.99.1.2 5.643e-232 743.0
HKD1_k127_7070615_10 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 488.0
HKD1_k127_7070615_11 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 472.0
HKD1_k127_7070615_12 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 451.0
HKD1_k127_7070615_13 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 448.0
HKD1_k127_7070615_14 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 413.0
HKD1_k127_7070615_15 Pyridoxal-phosphate dependent enzyme K12339,K21148 - 2.5.1.113,2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 406.0
HKD1_k127_7070615_16 Deoxyhypusine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 386.0
HKD1_k127_7070615_17 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 406.0
HKD1_k127_7070615_18 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 376.0
HKD1_k127_7070615_19 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 371.0
HKD1_k127_7070615_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 5.194e-198 632.0
HKD1_k127_7070615_20 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 354.0
HKD1_k127_7070615_21 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 327.0
HKD1_k127_7070615_22 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 329.0
HKD1_k127_7070615_23 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 321.0
HKD1_k127_7070615_24 Diphthamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 316.0
HKD1_k127_7070615_25 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 329.0
HKD1_k127_7070615_26 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 326.0
HKD1_k127_7070615_27 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 307.0
HKD1_k127_7070615_28 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 308.0
HKD1_k127_7070615_29 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 299.0
HKD1_k127_7070615_3 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 607.0
HKD1_k127_7070615_30 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009653 287.0
HKD1_k127_7070615_31 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001538 298.0
HKD1_k127_7070615_32 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001138 273.0
HKD1_k127_7070615_33 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002247 295.0
HKD1_k127_7070615_34 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005602 277.0
HKD1_k127_7070615_35 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003449 280.0
HKD1_k127_7070615_36 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004061 263.0
HKD1_k127_7070615_37 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001781 264.0
HKD1_k127_7070615_38 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000211 256.0
HKD1_k127_7070615_39 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002283 270.0
HKD1_k127_7070615_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 603.0
HKD1_k127_7070615_40 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000002818 254.0
HKD1_k127_7070615_41 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000003133 233.0
HKD1_k127_7070615_42 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000004275 229.0
HKD1_k127_7070615_43 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000006091 236.0
HKD1_k127_7070615_44 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000007119 228.0
HKD1_k127_7070615_45 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000005941 231.0
HKD1_k127_7070615_46 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000003094 213.0
HKD1_k127_7070615_47 PFAM ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000003926 211.0
HKD1_k127_7070615_48 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000002484 204.0
HKD1_k127_7070615_49 - - - - 0.0000000000000000000000000000000000000000000000000006249 196.0
HKD1_k127_7070615_5 Heat shock 70 kDa protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 587.0
HKD1_k127_7070615_50 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000006252 192.0
HKD1_k127_7070615_51 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000002416 186.0
HKD1_k127_7070615_52 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000000000000003964 173.0
HKD1_k127_7070615_53 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.000000000000000000000000000000000000000000006701 173.0
HKD1_k127_7070615_54 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000001594 171.0
HKD1_k127_7070615_55 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000003121 162.0
HKD1_k127_7070615_56 Membrane - - - 0.00000000000000000000000000000000000000001023 169.0
HKD1_k127_7070615_57 - - - - 0.00000000000000000000000000000000000000003954 166.0
HKD1_k127_7070615_58 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000001699 168.0
HKD1_k127_7070615_59 Transcriptional regulator - - - 0.000000000000000000000000000000000000001178 152.0
HKD1_k127_7070615_6 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 562.0
HKD1_k127_7070615_60 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000000002187 154.0
HKD1_k127_7070615_61 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000003135 157.0
HKD1_k127_7070615_62 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.000000000000000000000000000000000003388 152.0
HKD1_k127_7070615_63 PFAM heat shock protein DnaJ K04082 - - 0.00000000000000000000000000000000003696 145.0
HKD1_k127_7070615_64 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000004575 140.0
HKD1_k127_7070615_65 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000003658 142.0
HKD1_k127_7070615_66 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000485 139.0
HKD1_k127_7070615_67 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000003228 138.0
HKD1_k127_7070615_68 proteolysis - - - 0.000000000000000000000000000002777 124.0
HKD1_k127_7070615_69 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0034986,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000003392 122.0
HKD1_k127_7070615_7 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 494.0
HKD1_k127_7070615_70 methyltransferase activity - - - 0.000000000000000000000000000005334 132.0
HKD1_k127_7070615_71 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.000000000000000000000000008256 119.0
HKD1_k127_7070615_72 - - - - 0.000000000000000000000004237 113.0
HKD1_k127_7070615_73 Phage integrase family - - - 0.000000000000000000000004461 109.0
HKD1_k127_7070615_74 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000005277 104.0
HKD1_k127_7070615_75 Tetratricopeptide repeat - - - 0.0000000000000000000001795 110.0
HKD1_k127_7070615_76 FeS assembly protein IscX - - - 0.0000000000000000000005173 104.0
HKD1_k127_7070615_77 bleomycin resistance protein - - - 0.000000000000000000000794 99.0
HKD1_k127_7070615_78 - - - - 0.000000000000000000007847 97.0
HKD1_k127_7070615_79 - - - - 0.00000000000000000002757 102.0
HKD1_k127_7070615_8 quinolinate synthetase A activity K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 470.0
HKD1_k127_7070615_80 Frataxin-like domain K06202 - - 0.00000000000000000002765 93.0
HKD1_k127_7070615_81 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000005414 106.0
HKD1_k127_7070615_82 - - - - 0.0000000000000000003719 99.0
HKD1_k127_7070615_83 23S rRNA-intervening sequence protein - - - 0.0000000000000000005627 95.0
HKD1_k127_7070615_84 DNA-sulfur modification-associated - - - 0.00000000000000000246 98.0
HKD1_k127_7070615_85 Catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate K00619 - 2.3.1.1 0.000000000000000002981 99.0
HKD1_k127_7070615_86 OsmC-like protein K07397 - - 0.000000000000000005059 90.0
HKD1_k127_7070615_87 - - - - 0.0000000000000004211 88.0
HKD1_k127_7070615_88 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000106 79.0
HKD1_k127_7070615_89 - - - - 0.0000001494 61.0
HKD1_k127_7070615_9 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 481.0
HKD1_k127_7070615_90 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.0000002369 57.0
HKD1_k127_7070615_92 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000002971 55.0
HKD1_k127_7070615_95 Cupin 2, conserved barrel domain protein - - - 0.00002135 54.0
HKD1_k127_7070615_96 function. Source PGD - - - 0.00006573 53.0
HKD1_k127_7175333_0 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 623.0
HKD1_k127_7175333_1 COG0520 Selenocysteine lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 526.0
HKD1_k127_7175333_10 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005616 258.0
HKD1_k127_7175333_11 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000213 237.0
HKD1_k127_7175333_12 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000004483 237.0
HKD1_k127_7175333_13 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000002769 232.0
HKD1_k127_7175333_14 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000001196 164.0
HKD1_k127_7175333_15 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000003672 162.0
HKD1_k127_7175333_16 - - - - 0.00000000000000000000000000000000000001254 154.0
HKD1_k127_7175333_17 - - - - 0.0000000000000000000000000000000000004554 151.0
HKD1_k127_7175333_18 - - - - 0.0000000000000000000000000000000000006289 149.0
HKD1_k127_7175333_19 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000008013 138.0
HKD1_k127_7175333_2 transmembrane transporter activity K08196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 519.0
HKD1_k127_7175333_20 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000001051 118.0
HKD1_k127_7175333_21 - - - - 0.0000000000000000000000000008899 123.0
HKD1_k127_7175333_22 DoxX K15977 - - 0.00000000000000000000000002633 124.0
HKD1_k127_7175333_24 - - - - 0.00000000000000000000322 108.0
HKD1_k127_7175333_25 - - - - 0.000000000000000007625 96.0
HKD1_k127_7175333_26 - - - - 0.00000000000000004277 86.0
HKD1_k127_7175333_27 TIGRFAM TonB family protein K03832 - - 0.0000000000000008313 82.0
HKD1_k127_7175333_28 - - - - 0.0000000002646 67.0
HKD1_k127_7175333_29 TPR repeat-containing protein - - - 0.00000002189 68.0
HKD1_k127_7175333_3 Belongs to the alpha-IPM synthase homocitrate synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 404.0
HKD1_k127_7175333_30 DoxX K15977 - - 0.00003806 56.0
HKD1_k127_7175333_31 Lactoylglutathione lyase K01759,K15772 - 4.4.1.5 0.0004277 49.0
HKD1_k127_7175333_4 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 407.0
HKD1_k127_7175333_5 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 360.0
HKD1_k127_7175333_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 312.0
HKD1_k127_7175333_7 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004987 299.0
HKD1_k127_7175333_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001114 289.0
HKD1_k127_7175333_9 abc transporter atp-binding protein K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000001885 253.0
HKD1_k127_7201158_0 Dehydrogenase E1 component K11381 - 1.2.4.4 6.233e-269 848.0
HKD1_k127_7201158_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 1.403e-228 730.0
HKD1_k127_7201158_10 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 434.0
HKD1_k127_7201158_11 response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 413.0
HKD1_k127_7201158_12 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 406.0
HKD1_k127_7201158_13 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 393.0
HKD1_k127_7201158_14 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009909 389.0
HKD1_k127_7201158_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 373.0
HKD1_k127_7201158_16 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 363.0
HKD1_k127_7201158_17 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 340.0
HKD1_k127_7201158_18 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 346.0
HKD1_k127_7201158_19 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 344.0
HKD1_k127_7201158_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009143 571.0
HKD1_k127_7201158_20 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 335.0
HKD1_k127_7201158_21 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 339.0
HKD1_k127_7201158_22 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 331.0
HKD1_k127_7201158_23 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 334.0
HKD1_k127_7201158_24 FES K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 301.0
HKD1_k127_7201158_25 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 296.0
HKD1_k127_7201158_26 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003878 274.0
HKD1_k127_7201158_27 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000007029 234.0
HKD1_k127_7201158_28 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000003279 229.0
HKD1_k127_7201158_29 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000004038 236.0
HKD1_k127_7201158_3 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 546.0
HKD1_k127_7201158_30 TIGRFAM squalene-associated FAD-dependent desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000001229 232.0
HKD1_k127_7201158_31 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000005278 234.0
HKD1_k127_7201158_32 Squalene/phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000008351 221.0
HKD1_k127_7201158_33 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000007562 218.0
HKD1_k127_7201158_34 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000008174 194.0
HKD1_k127_7201158_35 NUDIX domain K00077,K01092,K03574,K03795 - 1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3 0.00000000000000000000000000000000000000000000000000002262 193.0
HKD1_k127_7201158_36 PFAM Rhomboid family - - - 0.000000000000000000000000000000000000000000000000001145 200.0
HKD1_k127_7201158_37 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000003994 192.0
HKD1_k127_7201158_38 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000004577 192.0
HKD1_k127_7201158_39 COGs COG2912 conserved - - - 0.0000000000000000000000000000000000000000000000005502 187.0
HKD1_k127_7201158_4 Peptidase dimerisation domain K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 549.0
HKD1_k127_7201158_40 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.000000000000000000000000000000000000000000000008345 187.0
HKD1_k127_7201158_41 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000001837 172.0
HKD1_k127_7201158_42 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000002636 170.0
HKD1_k127_7201158_43 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000003318 191.0
HKD1_k127_7201158_44 radical SAM K06871 - - 0.000000000000000000000000000000000000000000008419 181.0
HKD1_k127_7201158_45 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000005212 162.0
HKD1_k127_7201158_46 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000008322 173.0
HKD1_k127_7201158_47 Dienelactone hydrolase family K07018 - - 0.0000000000000000000000000000000000003606 157.0
HKD1_k127_7201158_48 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000004582 149.0
HKD1_k127_7201158_49 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000007634 136.0
HKD1_k127_7201158_5 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 501.0
HKD1_k127_7201158_50 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000001392 134.0
HKD1_k127_7201158_51 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000001224 128.0
HKD1_k127_7201158_52 Yqey-like protein K09117 - - 0.00000000000000000000000001418 124.0
HKD1_k127_7201158_53 - - - - 0.000000000000000000000001662 115.0
HKD1_k127_7201158_54 nUDIX hydrolase K03574,K03575 - 3.6.1.55 0.0000000000000000000000482 111.0
HKD1_k127_7201158_55 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000002919 105.0
HKD1_k127_7201158_56 Response regulator, receiver - - - 0.000000000000000006819 90.0
HKD1_k127_7201158_57 ATPase activity K14338 - 1.14.14.1,1.6.2.4 0.000000000000159 74.0
HKD1_k127_7201158_58 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000000001788 83.0
HKD1_k127_7201158_59 Serine aminopeptidase, S33 - - - 0.00000000006969 72.0
HKD1_k127_7201158_6 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007314 501.0
HKD1_k127_7201158_60 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000004753 70.0
HKD1_k127_7201158_61 - - - - 0.000002411 61.0
HKD1_k127_7201158_62 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.000002423 54.0
HKD1_k127_7201158_63 WD40 repeats - - - 0.000004166 59.0
HKD1_k127_7201158_7 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 462.0
HKD1_k127_7201158_8 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 449.0
HKD1_k127_7201158_9 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 455.0
HKD1_k127_7215475_0 Phosphoesterase family K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 461.0
HKD1_k127_7215475_1 Aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 372.0
HKD1_k127_7215475_2 glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 330.0
HKD1_k127_7215475_3 spheroidene biosynthetic process K09844 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016122,GO:0016123,GO:0016829,GO:0016835,GO:0016836,GO:0018904,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046148,GO:0071704,GO:1901178,GO:1901180,GO:1901503,GO:1901576 4.2.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000001175 259.0
HKD1_k127_7215475_4 Beta-lactamase superfamily domain K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000004639 239.0
HKD1_k127_7215475_5 - - - - 0.0000000000000000000000000000000000000000000001246 184.0
HKD1_k127_7215475_6 Polymer-forming cytoskeletal - - - 0.0000000000000000009509 93.0
HKD1_k127_7220790_0 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 559.0
HKD1_k127_7220790_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 556.0
HKD1_k127_7220790_10 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 330.0
HKD1_k127_7220790_11 GTPase activity K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 321.0
HKD1_k127_7220790_12 CoA-binding domain K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 316.0
HKD1_k127_7220790_13 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 308.0
HKD1_k127_7220790_14 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 306.0
HKD1_k127_7220790_15 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 302.0
HKD1_k127_7220790_16 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007024 282.0
HKD1_k127_7220790_17 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000002975 258.0
HKD1_k127_7220790_18 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000305 263.0
HKD1_k127_7220790_19 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000002693 198.0
HKD1_k127_7220790_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 516.0
HKD1_k127_7220790_20 peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000001761 199.0
HKD1_k127_7220790_21 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000002167 179.0
HKD1_k127_7220790_22 Stationary phase survival protein, YicC family, YicC_N and DUF1732 domain-containing - - - 0.000000000000000000000000000000000000000000002949 188.0
HKD1_k127_7220790_23 Dual specificity phosphatase, catalytic domain - - - 0.000000000000000000000000000000000000001081 152.0
HKD1_k127_7220790_24 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000001967 167.0
HKD1_k127_7220790_25 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000034 156.0
HKD1_k127_7220790_26 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000003338 155.0
HKD1_k127_7220790_27 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000005273 151.0
HKD1_k127_7220790_28 - - - - 0.00004021 52.0
HKD1_k127_7220790_3 GDP-mannose 4,6 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 469.0
HKD1_k127_7220790_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 466.0
HKD1_k127_7220790_5 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 401.0
HKD1_k127_7220790_6 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 376.0
HKD1_k127_7220790_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 375.0
HKD1_k127_7220790_8 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 383.0
HKD1_k127_7220790_9 PFAM PfkB domain protein K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 344.0
HKD1_k127_7227771_0 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 482.0
HKD1_k127_7227771_1 Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 476.0
HKD1_k127_7227771_10 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004242 243.0
HKD1_k127_7227771_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000105 203.0
HKD1_k127_7227771_12 negative regulation of cytoplasmic translation - - - 0.00000000000000000000000000000000000000000000000000000004371 215.0
HKD1_k127_7227771_13 - - - - 0.00000000000000000000000000000000000000000000002814 184.0
HKD1_k127_7227771_14 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000006812 165.0
HKD1_k127_7227771_15 FR47-like protein K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000004199 170.0
HKD1_k127_7227771_16 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000001098 156.0
HKD1_k127_7227771_17 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000001652 174.0
HKD1_k127_7227771_18 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000002445 151.0
HKD1_k127_7227771_19 Acetyltransferase (GNAT) domain K18816 - 2.3.1.82 0.0000000000000000000000000000000004234 136.0
HKD1_k127_7227771_2 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 465.0
HKD1_k127_7227771_20 Protein of unknown function (DUF1569) - - - 0.00000000000000000000000000000000276 134.0
HKD1_k127_7227771_21 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000004398 120.0
HKD1_k127_7227771_22 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000004591 95.0
HKD1_k127_7227771_23 transferase activity, transferring acyl groups K03824 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000009344 72.0
HKD1_k127_7227771_3 carboxylic ester hydrolase activity K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 470.0
HKD1_k127_7227771_4 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 430.0
HKD1_k127_7227771_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 364.0
HKD1_k127_7227771_6 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 294.0
HKD1_k127_7227771_7 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001001 282.0
HKD1_k127_7227771_8 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000152 276.0
HKD1_k127_7227771_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004548 267.0
HKD1_k127_7266828_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 527.0
HKD1_k127_7266828_1 outer membrane efflux - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 399.0
HKD1_k127_7266828_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K19595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002039 285.0
HKD1_k127_729947_0 Peptidase family M28 - - - 7.859e-199 635.0
HKD1_k127_729947_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 552.0
HKD1_k127_729947_10 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000002148 74.0
HKD1_k127_729947_12 PFAM ABC transporter related K02003 - - 0.0000355 51.0
HKD1_k127_729947_13 Tetratricopeptide repeat - - - 0.0009151 52.0
HKD1_k127_729947_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 343.0
HKD1_k127_729947_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 327.0
HKD1_k127_729947_4 Dehydrogenase K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000006069 233.0
HKD1_k127_729947_5 - - - - 0.00000000000000000000000000000000000000000001579 174.0
HKD1_k127_729947_6 Cytochrome c - - - 0.00000000000000000000000000000000000000139 154.0
HKD1_k127_729947_7 DNA-templated transcription, initiation - - - 0.0000000000000000000000000001059 122.0
HKD1_k127_729947_9 Limonene-1,2-epoxide hydrolase catalytic domain K10533 - 3.3.2.8 0.000000000001216 74.0
HKD1_k127_7350806_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1153.0
HKD1_k127_7350806_1 Heat shock 70 kDa protein K04043 - - 2.19e-291 906.0
HKD1_k127_7350806_10 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 555.0
HKD1_k127_7350806_11 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 557.0
HKD1_k127_7350806_12 Endoribonuclease that initiates mRNA decay K18682 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 527.0
HKD1_k127_7350806_13 PFAM aminotransferase, class I K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 518.0
HKD1_k127_7350806_14 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 482.0
HKD1_k127_7350806_15 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 452.0
HKD1_k127_7350806_16 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 451.0
HKD1_k127_7350806_17 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 415.0
HKD1_k127_7350806_18 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 415.0
HKD1_k127_7350806_19 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 385.0
HKD1_k127_7350806_2 Dehydrogenase K00117 - 1.1.5.2 1.986e-233 734.0
HKD1_k127_7350806_20 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 355.0
HKD1_k127_7350806_21 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 355.0
HKD1_k127_7350806_22 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 362.0
HKD1_k127_7350806_23 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 340.0
HKD1_k127_7350806_24 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 324.0
HKD1_k127_7350806_25 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 305.0
HKD1_k127_7350806_26 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 304.0
HKD1_k127_7350806_27 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 317.0
HKD1_k127_7350806_28 ATPases associated with a variety of cellular activities K05847 GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 300.0
HKD1_k127_7350806_29 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 307.0
HKD1_k127_7350806_3 Peptidase family M49 - - - 1.523e-224 708.0
HKD1_k127_7350806_30 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002667 292.0
HKD1_k127_7350806_31 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005964 285.0
HKD1_k127_7350806_32 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006475 285.0
HKD1_k127_7350806_33 protein homotetramerization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009065 270.0
HKD1_k127_7350806_34 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000001378 255.0
HKD1_k127_7350806_35 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000001498 256.0
HKD1_k127_7350806_36 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000006919 241.0
HKD1_k127_7350806_37 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000004486 245.0
HKD1_k127_7350806_38 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000006882 240.0
HKD1_k127_7350806_39 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000001699 229.0
HKD1_k127_7350806_4 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.564e-224 712.0
HKD1_k127_7350806_40 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000002474 220.0
HKD1_k127_7350806_41 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000005924 220.0
HKD1_k127_7350806_42 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000003157 211.0
HKD1_k127_7350806_43 Signal transduction histidine kinase, LytS K02478 - 2.7.13.3 0.00000000000000000000000000000000000000000000002848 184.0
HKD1_k127_7350806_44 PFAM AMMECR1 domain protein K09141 - - 0.000000000000000000000000000000000000000001285 163.0
HKD1_k127_7350806_45 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000879 151.0
HKD1_k127_7350806_46 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000006251 149.0
HKD1_k127_7350806_47 - - - - 0.000000000000000000000000000000002998 134.0
HKD1_k127_7350806_48 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000003664 132.0
HKD1_k127_7350806_49 S1/P1 Nuclease - - - 0.0000000000000000000000000000000718 136.0
HKD1_k127_7350806_5 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.499e-194 636.0
HKD1_k127_7350806_51 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000003966 124.0
HKD1_k127_7350806_52 phosphatase (DUF442) - - - 0.00000000000000000000000000001619 136.0
HKD1_k127_7350806_53 Mannosyltransferase (PIG-V) - - - 0.0000000000000000000000000001186 130.0
HKD1_k127_7350806_54 peptidase - - - 0.000000000000000000000000001329 126.0
HKD1_k127_7350806_55 - - - - 0.00000000000000000000000001533 113.0
HKD1_k127_7350806_56 - - - - 0.000000000000000000000000136 117.0
HKD1_k127_7350806_57 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000001943 111.0
HKD1_k127_7350806_58 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000001022 94.0
HKD1_k127_7350806_59 Regulatory protein, FmdB family - - - 0.00000000000000007926 82.0
HKD1_k127_7350806_6 (ABC) transporter K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 624.0
HKD1_k127_7350806_60 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000002054 81.0
HKD1_k127_7350806_61 3D domain - - - 0.0000000000000004524 85.0
HKD1_k127_7350806_62 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000002245 86.0
HKD1_k127_7350806_63 - - - - 0.00000000000003236 77.0
HKD1_k127_7350806_64 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000001691 78.0
HKD1_k127_7350806_65 - - - - 0.0000000000006907 79.0
HKD1_k127_7350806_67 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000002052 70.0
HKD1_k127_7350806_68 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000001301 68.0
HKD1_k127_7350806_69 cAMP biosynthetic process - - - 0.0000000006171 73.0
HKD1_k127_7350806_7 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 567.0
HKD1_k127_7350806_71 SnoaL-like domain - - - 0.0000005617 58.0
HKD1_k127_7350806_72 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0003061 48.0
HKD1_k127_7350806_8 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 575.0
HKD1_k127_7350806_9 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 580.0
HKD1_k127_7362773_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 472.0
HKD1_k127_7362773_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 404.0
HKD1_k127_7362773_10 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000001276 140.0
HKD1_k127_7362773_11 Alpha/beta hydrolase family - - - 0.000000000000000000000000000004574 123.0
HKD1_k127_7362773_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 323.0
HKD1_k127_7362773_3 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000006245 269.0
HKD1_k127_7362773_5 molybdenum ion binding K07140 - - 0.00000000000000000000000000000000000000000000000000000000004854 214.0
HKD1_k127_7362773_6 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000001137 201.0
HKD1_k127_7362773_7 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000001336 192.0
HKD1_k127_7362773_8 - - - - 0.0000000000000000000000000000000000000000003472 168.0
HKD1_k127_7362773_9 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000007975 143.0
HKD1_k127_73632_0 Subtilase family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 501.0
HKD1_k127_73632_1 Subtilase family - - - 0.00000002362 63.0
HKD1_k127_7388172_0 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 632.0
HKD1_k127_7388172_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 621.0
HKD1_k127_7388172_10 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.0000000000000000000000000000000000003544 151.0
HKD1_k127_7388172_11 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000001395 148.0
HKD1_k127_7388172_12 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000736 145.0
HKD1_k127_7388172_13 - - - - 0.000000000000000000000000001175 119.0
HKD1_k127_7388172_14 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000003409 98.0
HKD1_k127_7388172_15 - - - - 0.0000000000000000006966 91.0
HKD1_k127_7388172_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000001226 90.0
HKD1_k127_7388172_18 Methyltransferase domain - - - 0.000000000001041 77.0
HKD1_k127_7388172_19 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000005072 56.0
HKD1_k127_7388172_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 541.0
HKD1_k127_7388172_20 glyoxalase bleomycin resistance protein dioxygenase K20431 - 5.1.3.33 0.00001389 54.0
HKD1_k127_7388172_21 Cupin domain - - - 0.00004938 56.0
HKD1_k127_7388172_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 383.0
HKD1_k127_7388172_4 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 361.0
HKD1_k127_7388172_5 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002801 276.0
HKD1_k127_7388172_6 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000009749 209.0
HKD1_k127_7388172_7 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000005118 213.0
HKD1_k127_7388172_8 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000000000000000000000000000000000000000000000000000002125 204.0
HKD1_k127_7388172_9 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000002892 186.0
HKD1_k127_7455402_0 PQQ-like domain K00117 - 1.1.5.2 2.639e-213 681.0
HKD1_k127_7455402_1 PQQ-like domain K00117 - 1.1.5.2 3.511e-212 678.0
HKD1_k127_7455402_10 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 322.0
HKD1_k127_7455402_11 Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002882 291.0
HKD1_k127_7455402_12 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000405 282.0
HKD1_k127_7455402_13 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001804 277.0
HKD1_k127_7455402_14 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006582 253.0
HKD1_k127_7455402_15 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000007257 233.0
HKD1_k127_7455402_17 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000009311 156.0
HKD1_k127_7455402_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000003484 143.0
HKD1_k127_7455402_19 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000617 141.0
HKD1_k127_7455402_2 PFAM glycine cleavage T protein (aminomethyl transferase) - - - 2.232e-199 632.0
HKD1_k127_7455402_22 - - - - 0.000000000000000000001353 111.0
HKD1_k127_7455402_23 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000000001416 111.0
HKD1_k127_7455402_24 photosystem II stabilization K02237 - - 0.000008491 57.0
HKD1_k127_7455402_3 PQQ-like domain K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 596.0
HKD1_k127_7455402_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 449.0
HKD1_k127_7455402_5 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 397.0
HKD1_k127_7455402_6 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 407.0
HKD1_k127_7455402_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 381.0
HKD1_k127_7455402_8 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 388.0
HKD1_k127_7455402_9 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 340.0
HKD1_k127_7486795_0 polyketide synthase - - - 0.0 3218.0
HKD1_k127_7486795_1 acyl transferase domain - - - 0.0 1718.0
HKD1_k127_7486795_10 non-ribosomal peptide synthetase - - - 8.067e-210 739.0
HKD1_k127_7486795_11 Heparinase II/III N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 568.0
HKD1_k127_7486795_12 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 465.0
HKD1_k127_7486795_13 undecaprenyl-phosphate glucose phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 424.0
HKD1_k127_7486795_14 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 372.0
HKD1_k127_7486795_15 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 301.0
HKD1_k127_7486795_16 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000139 298.0
HKD1_k127_7486795_17 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000916 284.0
HKD1_k127_7486795_18 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003781 251.0
HKD1_k127_7486795_19 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000003598 240.0
HKD1_k127_7486795_2 Ketoacyl-synthetase C-terminal extension - - - 0.0 1474.0
HKD1_k127_7486795_20 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000001689 231.0
HKD1_k127_7486795_21 - - - - 0.00000000000000000000000000000000000000000000000000000000006279 232.0
HKD1_k127_7486795_22 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000007663 216.0
HKD1_k127_7486795_23 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000003574 181.0
HKD1_k127_7486795_24 Aspartyl/Asparaginyl beta-hydroxylase K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000009391 173.0
HKD1_k127_7486795_25 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000352 164.0
HKD1_k127_7486795_26 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000002148 168.0
HKD1_k127_7486795_27 Transport permease protein K01992 - - 0.0000000000000000000001434 107.0
HKD1_k127_7486795_3 COGs COG3321 Polyketide synthase modules and related protein - - - 0.0 1460.0
HKD1_k127_7486795_4 Ketoacyl-synthetase C-terminal extension - - - 0.0 1429.0
HKD1_k127_7486795_5 polyketide synthase - - - 0.0 1307.0
HKD1_k127_7486795_6 acyl transferase domain - - - 0.0 1257.0
HKD1_k127_7486795_7 PKS_DH - - - 0.0 1247.0
HKD1_k127_7486795_8 Amino acid adenylation domain - - - 9.4e-323 1025.0
HKD1_k127_7486795_9 Condensation domain - - - 5.77e-310 986.0
HKD1_k127_7489552_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 5.827e-228 715.0
HKD1_k127_7489552_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 584.0
HKD1_k127_7517801_0 Dienelactone hydrolase family - - - 1.579e-214 690.0
HKD1_k127_7517801_1 Biotin carboxylase K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 512.0
HKD1_k127_7517801_10 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.00000000000000000006096 105.0
HKD1_k127_7517801_11 Belongs to the 'phage' integrase family - - - 0.00000000003605 67.0
HKD1_k127_7517801_12 metallopeptidase activity - - - 0.0000008209 63.0
HKD1_k127_7517801_13 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000784 59.0
HKD1_k127_7517801_14 - - - - 0.00002013 57.0
HKD1_k127_7517801_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 497.0
HKD1_k127_7517801_3 antiporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 414.0
HKD1_k127_7517801_4 N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 332.0
HKD1_k127_7517801_5 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 322.0
HKD1_k127_7517801_6 Coenzyme A transferase K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 304.0
HKD1_k127_7517801_7 TIGRFAM para-aminobenzoate synthase, subunit I K01665,K03342 - 2.6.1.85,4.1.3.38 0.000000000000000000000000000000000000000000000000000002169 198.0
HKD1_k127_7517801_8 Haem-degrading - - - 0.00000000000000000000000000000002845 132.0
HKD1_k127_7517801_9 - - - - 0.0000000000000000000000003877 116.0
HKD1_k127_7558961_0 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000001136 211.0
HKD1_k127_7558961_1 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000005196 192.0
HKD1_k127_7558961_2 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000008749 136.0
HKD1_k127_7558961_3 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000002316 93.0
HKD1_k127_7558961_4 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000004293 59.0
HKD1_k127_7558961_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00007818 50.0
HKD1_k127_7565128_0 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 307.0
HKD1_k127_7565128_1 Polysaccharide lyase family 4, domain II - - - 0.0000000000000000000000000000000000000000000000000000000000000000001108 239.0
HKD1_k127_7565128_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000001115 254.0
HKD1_k127_7565128_3 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000000000000000000000008583 206.0
HKD1_k127_7565128_4 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000000002981 157.0
HKD1_k127_7565128_5 PFAM transposase, IS111A IS1328 IS1533 K07486 - - 0.0000002753 52.0
HKD1_k127_7588776_0 Phosphoribulokinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 474.0
HKD1_k127_7588776_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000003797 179.0
HKD1_k127_7588776_2 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000001832 107.0
HKD1_k127_75979_0 Dehydrogenase K00117,K19813 - 1.1.5.2,1.1.5.9 2.439e-215 687.0
HKD1_k127_75979_1 DNA topological change K03168 - 5.99.1.2 8.171e-195 636.0
HKD1_k127_75979_10 glycerophosphodiester transmembrane transport K02026,K08715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004716 287.0
HKD1_k127_75979_11 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000002289 233.0
HKD1_k127_75979_12 - - - - 0.000000000000000000000000009302 118.0
HKD1_k127_75979_13 PFAM PKD domain containing protein - - - 0.000000000000000000000001887 115.0
HKD1_k127_75979_15 deoxyhypusine monooxygenase activity - - - 0.0000003934 57.0
HKD1_k127_75979_2 Dehydrogenase K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 589.0
HKD1_k127_75979_3 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 399.0
HKD1_k127_75979_4 Mo-co oxidoreductase dimerisation domain K17225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 398.0
HKD1_k127_75979_5 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 375.0
HKD1_k127_75979_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 336.0
HKD1_k127_75979_7 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 304.0
HKD1_k127_75979_8 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 319.0
HKD1_k127_75979_9 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 311.0
HKD1_k127_7598481_0 Tricorn protease homolog K08676 - - 8.814e-207 664.0
HKD1_k127_7598481_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 411.0
HKD1_k127_7685357_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0 1170.0
HKD1_k127_7685357_1 Glutamine synthetase type III K01915 - 6.3.1.2 9.091e-297 927.0
HKD1_k127_7685357_10 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 462.0
HKD1_k127_7685357_11 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 456.0
HKD1_k127_7685357_12 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 464.0
HKD1_k127_7685357_13 COG COG1132 ABC-type multidrug transport system ATPase and permease components Defense mechanisms K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 452.0
HKD1_k127_7685357_14 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 422.0
HKD1_k127_7685357_15 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 402.0
HKD1_k127_7685357_16 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 377.0
HKD1_k127_7685357_17 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 356.0
HKD1_k127_7685357_18 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 358.0
HKD1_k127_7685357_19 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 349.0
HKD1_k127_7685357_2 COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit K02469 - 5.99.1.3 1.101e-288 907.0
HKD1_k127_7685357_20 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 332.0
HKD1_k127_7685357_21 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 329.0
HKD1_k127_7685357_22 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 327.0
HKD1_k127_7685357_23 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 319.0
HKD1_k127_7685357_24 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 316.0
HKD1_k127_7685357_25 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 316.0
HKD1_k127_7685357_26 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 314.0
HKD1_k127_7685357_27 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 295.0
HKD1_k127_7685357_28 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 297.0
HKD1_k127_7685357_29 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003756 294.0
HKD1_k127_7685357_3 COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit K02470,K02622 - 5.99.1.3 2.267e-279 871.0
HKD1_k127_7685357_30 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001136 298.0
HKD1_k127_7685357_31 Domain of Unknown Function (DUF349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001248 298.0
HKD1_k127_7685357_32 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002022 264.0
HKD1_k127_7685357_33 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000003807 242.0
HKD1_k127_7685357_34 PFAM Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000007664 232.0
HKD1_k127_7685357_35 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000005506 231.0
HKD1_k127_7685357_36 PFAM Peptidoglycan-binding domain 1 protein K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000003228 246.0
HKD1_k127_7685357_37 - K06921 - - 0.0000000000000000000000000000000000000000000000000000000000000006472 233.0
HKD1_k127_7685357_38 UDP-glucoronosyl and UDP-glucosyl transferase K16444 - 2.4.1.310 0.0000000000000000000000000000000000000000000000000000000000001859 227.0
HKD1_k127_7685357_39 cellulase activity K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000003904 229.0
HKD1_k127_7685357_4 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 4.461e-257 803.0
HKD1_k127_7685357_40 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000007422 207.0
HKD1_k127_7685357_41 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000001503 195.0
HKD1_k127_7685357_42 mitochondrion morphogenesis K06195 - - 0.000000000000000000000000000000000000000000001066 168.0
HKD1_k127_7685357_43 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000001705 182.0
HKD1_k127_7685357_44 Hydrolase of the alpha beta-hydrolase K07020 - - 0.00000000000000000000000000000000000000000001141 171.0
HKD1_k127_7685357_45 Ferredoxin - - - 0.0000000000000000000000000000000000000000001982 162.0
HKD1_k127_7685357_46 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000002404 164.0
HKD1_k127_7685357_47 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000000000000000000000009489 150.0
HKD1_k127_7685357_48 NUDIX domain - - - 0.00000000000000000000000000000000000001461 155.0
HKD1_k127_7685357_49 GDSL-like lipase acylhydrolase domain protein - - - 0.00000000000000000000000000000000000004428 156.0
HKD1_k127_7685357_5 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 5.01e-242 755.0
HKD1_k127_7685357_50 GlcNAc-PI de-N-acetylase K15525 - 3.5.1.103 0.0000000000000000000000000000000000001473 153.0
HKD1_k127_7685357_51 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000008373 142.0
HKD1_k127_7685357_52 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000003782 152.0
HKD1_k127_7685357_53 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000005238 150.0
HKD1_k127_7685357_54 - - - - 0.000000000000000000000000000000004372 143.0
HKD1_k127_7685357_55 Methyltransferase domain - - - 0.00000000000000000000000000001381 134.0
HKD1_k127_7685357_56 BON domain - - - 0.0000000000000000000000000001374 123.0
HKD1_k127_7685357_57 PFAM Bacterial regulatory proteins, gntR family K07979 - - 0.00000000000000000001913 95.0
HKD1_k127_7685357_58 - - - - 0.00000000000000004677 87.0
HKD1_k127_7685357_59 SNARE associated Golgi protein - - - 0.000000000003587 73.0
HKD1_k127_7685357_6 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 9.95e-205 644.0
HKD1_k127_7685357_60 tetratricopeptide repeat - - - 0.0000000002085 73.0
HKD1_k127_7685357_61 Cytochrome c K00413 - - 0.0000000006939 66.0
HKD1_k127_7685357_62 Acetyltransferase (GNAT) domain - - - 0.000000002116 66.0
HKD1_k127_7685357_63 Type II secretory pathway, component PulD - - - 0.00000001329 67.0
HKD1_k127_7685357_64 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000937 60.0
HKD1_k127_7685357_65 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00002106 58.0
HKD1_k127_7685357_7 PFAM Glycosyl transferase family 2 - - - 2.926e-198 664.0
HKD1_k127_7685357_8 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 614.0
HKD1_k127_7685357_9 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 490.0
HKD1_k127_770180_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 480.0
HKD1_k127_770180_1 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 456.0
HKD1_k127_770180_10 Phosphatidylethanolamine-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000002567 222.0
HKD1_k127_770180_11 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001764 234.0
HKD1_k127_770180_12 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000003348 177.0
HKD1_k127_770180_13 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000001289 171.0
HKD1_k127_770180_14 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000001744 145.0
HKD1_k127_770180_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000001295 124.0
HKD1_k127_770180_16 Pirin K06911 - - 0.0000000000000000000806 89.0
HKD1_k127_770180_17 DinB family - - - 0.00000000000000003796 89.0
HKD1_k127_770180_19 - - - - 0.000000064 63.0
HKD1_k127_770180_2 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 392.0
HKD1_k127_770180_3 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 354.0
HKD1_k127_770180_4 major facilitator superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 316.0
HKD1_k127_770180_5 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 308.0
HKD1_k127_770180_6 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 299.0
HKD1_k127_770180_7 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 304.0
HKD1_k127_770180_8 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001308 294.0
HKD1_k127_770180_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003404 246.0
HKD1_k127_7706099_0 Zinc carboxypeptidase - - - 0.0 1099.0
HKD1_k127_7706099_1 Aldehyde dehydrogenase family K00138 - - 5.631e-254 789.0
HKD1_k127_7706099_10 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008348 446.0
HKD1_k127_7706099_11 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 421.0
HKD1_k127_7706099_12 Uncharacterised MFS-type transporter YbfB K08369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 414.0
HKD1_k127_7706099_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 386.0
HKD1_k127_7706099_14 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 333.0
HKD1_k127_7706099_15 DNA modification - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 347.0
HKD1_k127_7706099_16 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 314.0
HKD1_k127_7706099_17 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 301.0
HKD1_k127_7706099_18 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000001035 268.0
HKD1_k127_7706099_19 PFAM helicase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001329 240.0
HKD1_k127_7706099_2 pyrroloquinoline quinone binding - - - 3.157e-214 684.0
HKD1_k127_7706099_20 TIGRFAM CitB domain protein K13795 - - 0.0000000000000000000000000000000000000000000000000000000000002256 217.0
HKD1_k127_7706099_21 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000002031 224.0
HKD1_k127_7706099_22 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000001518 207.0
HKD1_k127_7706099_23 DinB family - - - 0.000000000000000000000000000000000000000000000000000214 190.0
HKD1_k127_7706099_24 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000001261 199.0
HKD1_k127_7706099_25 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000000000000000000002457 177.0
HKD1_k127_7706099_26 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000001015 191.0
HKD1_k127_7706099_27 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000005488 149.0
HKD1_k127_7706099_28 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000002332 150.0
HKD1_k127_7706099_29 BMC domain K04027 - - 0.000000000000000000000000000000366 126.0
HKD1_k127_7706099_3 Peptidase family M28 - - - 2.404e-206 656.0
HKD1_k127_7706099_30 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.00000000000000000006446 95.0
HKD1_k127_7706099_32 helix_turn_helix, mercury resistance - - - 0.00000000000000709 84.0
HKD1_k127_7706099_33 hyperosmotic response - - - 0.00000000003068 74.0
HKD1_k127_7706099_35 PFAM S23 ribosomal protein - - - 0.0003267 46.0
HKD1_k127_7706099_4 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 546.0
HKD1_k127_7706099_5 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 528.0
HKD1_k127_7706099_6 metallocarboxypeptidase activity K14054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 538.0
HKD1_k127_7706099_7 Isocitrate/isopropylmalate dehydrogenase K07246 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006108,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009027,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019752,GO:0036094,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046553,GO:0046872,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008302 499.0
HKD1_k127_7706099_8 symporter activity K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 496.0
HKD1_k127_7706099_9 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 475.0
HKD1_k127_7706537_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 1.529e-240 774.0
HKD1_k127_7706537_1 Peptidase family M1 domain K01256 - 3.4.11.2 3.808e-239 766.0
HKD1_k127_7706537_10 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001134 302.0
HKD1_k127_7706537_11 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003811 283.0
HKD1_k127_7706537_12 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002774 260.0
HKD1_k127_7706537_13 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000005724 245.0
HKD1_k127_7706537_14 branched-chain amino acid transmembrane transporter activity K01996 - - 0.00000000000000000000000000000000000000000000000000000000000003106 221.0
HKD1_k127_7706537_15 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000009539 228.0
HKD1_k127_7706537_16 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000003756 204.0
HKD1_k127_7706537_17 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000001097 205.0
HKD1_k127_7706537_18 Zn-dependent hydrolases of the beta-lactamase fold K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000001161 199.0
HKD1_k127_7706537_19 Glucose dehydrogenase C-terminus K00001,K00344 - 1.1.1.1,1.6.5.5 0.0000000000000000000000000000000000000000000000000007455 206.0
HKD1_k127_7706537_2 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 553.0
HKD1_k127_7706537_20 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000021 157.0
HKD1_k127_7706537_21 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000002548 163.0
HKD1_k127_7706537_22 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000003991 137.0
HKD1_k127_7706537_23 Cytochrome c - - - 0.000000000000000000000000000000249 134.0
HKD1_k127_7706537_24 membrane K08972 - - 0.000000000000000000000000000001198 127.0
HKD1_k127_7706537_25 Protein of unknown function (DUF861) - - - 0.000000000000000000000000382 121.0
HKD1_k127_7706537_26 Lactoylglutathione lyase K08234 - - 0.000000001594 65.0
HKD1_k127_7706537_27 - - - - 0.000000002395 68.0
HKD1_k127_7706537_28 PFAM PEGA domain - - - 0.0000008774 61.0
HKD1_k127_7706537_29 protein possibly involved in utilization of glycolate and propanediol - - - 0.0000503 57.0
HKD1_k127_7706537_3 PFAM amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 358.0
HKD1_k127_7706537_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 351.0
HKD1_k127_7706537_5 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 349.0
HKD1_k127_7706537_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 339.0
HKD1_k127_7706537_7 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 336.0
HKD1_k127_7706537_8 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 331.0
HKD1_k127_7706537_9 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 293.0
HKD1_k127_7717089_0 alpha amylase, catalytic region - - - 2.259e-272 842.0
HKD1_k127_7717089_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 2.136e-268 836.0
HKD1_k127_7717089_10 Mo-co oxidoreductase dimerisation domain K17225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 463.0
HKD1_k127_7717089_11 Aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 464.0
HKD1_k127_7717089_12 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 452.0
HKD1_k127_7717089_13 hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 407.0
HKD1_k127_7717089_14 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 428.0
HKD1_k127_7717089_15 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 383.0
HKD1_k127_7717089_16 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 369.0
HKD1_k127_7717089_17 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 290.0
HKD1_k127_7717089_18 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001236 267.0
HKD1_k127_7717089_19 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002876 273.0
HKD1_k127_7717089_2 serine dehydratase beta chain K01752 - 4.3.1.17 7.32e-252 787.0
HKD1_k127_7717089_20 ankyrin repeat K15503 - - 0.00000000000000000000000000000000000000000000000000000000001976 225.0
HKD1_k127_7717089_21 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000000000000006254 204.0
HKD1_k127_7717089_22 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.00000000000000000000000000000000000000000000000002241 190.0
HKD1_k127_7717089_23 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000000000000000000334 182.0
HKD1_k127_7717089_24 peptidase - - - 0.0000000000000000000000000000000000000000000000006617 199.0
HKD1_k127_7717089_25 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000003247 173.0
HKD1_k127_7717089_26 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000002927 166.0
HKD1_k127_7717089_27 - - - - 0.00000000000000000000000000000000000000001006 166.0
HKD1_k127_7717089_28 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000003382 145.0
HKD1_k127_7717089_29 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000009692 147.0
HKD1_k127_7717089_3 PFAM HypF finger K04656 - - 3.577e-251 799.0
HKD1_k127_7717089_30 ABC transporter K06158 GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 - 0.0000000000000000000000000000000001077 133.0
HKD1_k127_7717089_31 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000002556 141.0
HKD1_k127_7717089_32 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000006967 136.0
HKD1_k127_7717089_33 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000000001115 143.0
HKD1_k127_7717089_34 NIPSNAP - - - 0.0000000000000000000000000000001947 140.0
HKD1_k127_7717089_35 - - - - 0.0000000000000000000000000000002629 132.0
HKD1_k127_7717089_36 SMP-30/Gluconolaconase/LRE-like region - - - 0.0000000000000000000000000000003085 142.0
HKD1_k127_7717089_37 Protein of unknown function (DUF1109) - - - 0.00000000000000000000000000003198 125.0
HKD1_k127_7717089_38 - - - - 0.0000000000000000000000000009333 126.0
HKD1_k127_7717089_39 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000001857 113.0
HKD1_k127_7717089_4 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 581.0
HKD1_k127_7717089_40 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000006818 106.0
HKD1_k127_7717089_41 Transcriptional regulator - - - 0.0000000000000000000003102 96.0
HKD1_k127_7717089_42 - - - - 0.00000000000000001315 98.0
HKD1_k127_7717089_43 - - - - 0.00000000000000003904 92.0
HKD1_k127_7717089_44 - - - - 0.0000000000000004065 83.0
HKD1_k127_7717089_45 DoxX K15977 - - 0.00000000000000441 78.0
HKD1_k127_7717089_46 Sigma-70 region 2 K03088 - - 0.00000000000001783 79.0
HKD1_k127_7717089_47 permease K07243 - - 0.00000000000007597 76.0
HKD1_k127_7717089_48 - - - - 0.00000000000009221 83.0
HKD1_k127_7717089_49 - - - - 0.00000000001657 72.0
HKD1_k127_7717089_5 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 593.0
HKD1_k127_7717089_50 - - - - 0.00000000005728 68.0
HKD1_k127_7717089_51 Peptidoglycan-binding domain 1 protein - - - 0.000000006681 61.0
HKD1_k127_7717089_52 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000001019 57.0
HKD1_k127_7717089_53 - - - - 0.0000001734 63.0
HKD1_k127_7717089_6 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 552.0
HKD1_k127_7717089_7 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 514.0
HKD1_k127_7717089_8 cell adhesion involved in biofilm formation K01186 - 3.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 516.0
HKD1_k127_7717089_9 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 470.0
HKD1_k127_7728963_0 TonB-dependent Receptor Plug Domain - - - 0.0 1015.0
HKD1_k127_7728963_1 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 1.508e-264 824.0
HKD1_k127_7728963_10 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 504.0
HKD1_k127_7728963_11 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 516.0
HKD1_k127_7728963_12 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 465.0
HKD1_k127_7728963_13 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 440.0
HKD1_k127_7728963_14 Twin-arginine translocation pathway signal sequence - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 438.0
HKD1_k127_7728963_15 belongs to the thioredoxin family K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 449.0
HKD1_k127_7728963_16 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 424.0
HKD1_k127_7728963_17 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 389.0
HKD1_k127_7728963_18 Membrane dipeptidase (Peptidase family M19) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 379.0
HKD1_k127_7728963_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 361.0
HKD1_k127_7728963_2 Amidase K01426 - 3.5.1.4 7.056e-212 671.0
HKD1_k127_7728963_20 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 333.0
HKD1_k127_7728963_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002946 262.0
HKD1_k127_7728963_22 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000003458 252.0
HKD1_k127_7728963_23 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002213 256.0
HKD1_k127_7728963_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004596 259.0
HKD1_k127_7728963_25 Glycosyl transferase family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000226 234.0
HKD1_k127_7728963_26 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000002449 215.0
HKD1_k127_7728963_27 protein kinase activity K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000001661 212.0
HKD1_k127_7728963_28 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000006828 214.0
HKD1_k127_7728963_29 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000001146 194.0
HKD1_k127_7728963_3 PQQ-like domain K05889 - 1.1.2.6 2.606e-200 654.0
HKD1_k127_7728963_30 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000001145 173.0
HKD1_k127_7728963_31 Haem-degrading - - - 0.000000000000000000000000000000000000000000334 164.0
HKD1_k127_7728963_32 - - - - 0.00000000000000000000000000000000000000002018 158.0
HKD1_k127_7728963_33 - - - - 0.00000000000000000000000000000004957 146.0
HKD1_k127_7728963_34 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000002866 127.0
HKD1_k127_7728963_35 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000001309 135.0
HKD1_k127_7728963_36 DoxX K15977 - - 0.0000000000000000000000000004164 119.0
HKD1_k127_7728963_37 cell redox homeostasis K02199 - - 0.00000000000000000000000008239 123.0
HKD1_k127_7728963_38 transmembrane transport - - - 0.000000000000000000000001401 116.0
HKD1_k127_7728963_39 peptidase S8 and S53, subtilisin, kexin, sedolisin K14645 - - 0.00000000000000000000329 110.0
HKD1_k127_7728963_4 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007263 620.0
HKD1_k127_7728963_40 - - - - 0.000000000000000001126 98.0
HKD1_k127_7728963_41 PFAM Tetratricopeptide - - - 0.000000000001134 82.0
HKD1_k127_7728963_42 TPR repeat - - - 0.000000000002282 80.0
HKD1_k127_7728963_43 STAS domain - - - 0.000000001007 65.0
HKD1_k127_7728963_44 Phosphate-selective porin O and P K07221 - - 0.0009819 49.0
HKD1_k127_7728963_5 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008124 590.0
HKD1_k127_7728963_6 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 557.0
HKD1_k127_7728963_7 Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate K11103 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 503.0
HKD1_k127_7728963_8 Belongs to the peptidase S1B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 509.0
HKD1_k127_7728963_9 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 477.0
HKD1_k127_7777334_0 Heat shock 70 kDa protein K04043 - - 1.621e-301 936.0
HKD1_k127_7777334_1 DNA topological change K03168 - 5.99.1.2 1.853e-241 777.0
HKD1_k127_7777334_10 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001805 275.0
HKD1_k127_7777334_11 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000844 240.0
HKD1_k127_7777334_12 - - - - 0.0000000000001773 73.0
HKD1_k127_7777334_13 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.000000001422 62.0
HKD1_k127_7777334_14 CHRD domain containing protein - - - 0.000000005577 63.0
HKD1_k127_7777334_2 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 622.0
HKD1_k127_7777334_3 MviN-like protein K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 576.0
HKD1_k127_7777334_4 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 504.0
HKD1_k127_7777334_5 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 426.0
HKD1_k127_7777334_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 404.0
HKD1_k127_7777334_7 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 340.0
HKD1_k127_7777334_8 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 324.0
HKD1_k127_7777334_9 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 316.0
HKD1_k127_7784245_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1479.0
HKD1_k127_7784245_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.443e-298 927.0
HKD1_k127_7784245_10 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 463.0
HKD1_k127_7784245_11 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 451.0
HKD1_k127_7784245_12 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 455.0
HKD1_k127_7784245_13 PFAM Cytochrome b b6 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 425.0
HKD1_k127_7784245_14 Cytochrome b(C-terminal)/b6/petD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 395.0
HKD1_k127_7784245_15 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 380.0
HKD1_k127_7784245_16 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 401.0
HKD1_k127_7784245_17 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 373.0
HKD1_k127_7784245_18 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 351.0
HKD1_k127_7784245_19 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 341.0
HKD1_k127_7784245_2 Acetolactate synthase, large subunit K01652 - 2.2.1.6 4.937e-283 878.0
HKD1_k127_7784245_20 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 305.0
HKD1_k127_7784245_21 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007716 284.0
HKD1_k127_7784245_22 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001644 277.0
HKD1_k127_7784245_23 PFAM NAD binding domain of 6-phosphogluconate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000001106 252.0
HKD1_k127_7784245_24 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000009491 240.0
HKD1_k127_7784245_25 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000001801 241.0
HKD1_k127_7784245_26 Transporter associated domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000003033 231.0
HKD1_k127_7784245_27 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000006532 210.0
HKD1_k127_7784245_28 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000006242 224.0
HKD1_k127_7784245_29 6-phosphogluconate dehydrogenase, NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000003881 212.0
HKD1_k127_7784245_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.804e-252 812.0
HKD1_k127_7784245_30 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000002154 199.0
HKD1_k127_7784245_31 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000001815 197.0
HKD1_k127_7784245_32 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000001552 173.0
HKD1_k127_7784245_33 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000002651 130.0
HKD1_k127_7784245_34 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000002285 123.0
HKD1_k127_7784245_35 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000005529 105.0
HKD1_k127_7784245_36 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000001093 91.0
HKD1_k127_7784245_37 Mediates influx of magnesium ions K03284 - - 0.00000000000000002106 92.0
HKD1_k127_7784245_38 MlaD protein K02067 - - 0.0000000000000003827 90.0
HKD1_k127_7784245_39 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000003154 74.0
HKD1_k127_7784245_4 DNA topological change K03168 - 5.99.1.2 9.868e-206 669.0
HKD1_k127_7784245_40 lyase activity - - - 0.00000002348 65.0
HKD1_k127_7784245_41 YtxH-like protein - - - 0.00000004992 58.0
HKD1_k127_7784245_42 Patatin phospholipase K07001 - - 0.00005269 57.0
HKD1_k127_7784245_43 - - - - 0.000509 53.0
HKD1_k127_7784245_5 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 574.0
HKD1_k127_7784245_6 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 570.0
HKD1_k127_7784245_7 AAA ATPase, central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 535.0
HKD1_k127_7784245_8 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 531.0
HKD1_k127_7784245_9 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 479.0
HKD1_k127_779244_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1158.0
HKD1_k127_779244_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.268e-221 695.0
HKD1_k127_779244_10 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 486.0
HKD1_k127_779244_11 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 458.0
HKD1_k127_779244_12 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 425.0
HKD1_k127_779244_13 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 411.0
HKD1_k127_779244_14 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 394.0
HKD1_k127_779244_15 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 389.0
HKD1_k127_779244_16 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 371.0
HKD1_k127_779244_17 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 347.0
HKD1_k127_779244_18 PFAM Binding-protein-dependent transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 344.0
HKD1_k127_779244_19 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 342.0
HKD1_k127_779244_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.184e-217 691.0
HKD1_k127_779244_20 SpoIVB peptidase S55 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 343.0
HKD1_k127_779244_21 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 331.0
HKD1_k127_779244_22 DnaJ molecular chaperone homology domain K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 316.0
HKD1_k127_779244_23 response regulator, receiver K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 295.0
HKD1_k127_779244_24 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001297 301.0
HKD1_k127_779244_25 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001072 287.0
HKD1_k127_779244_26 Shikimate dehydrogenase substrate binding domain K13832 - 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000147 290.0
HKD1_k127_779244_27 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003048 278.0
HKD1_k127_779244_28 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008014 282.0
HKD1_k127_779244_29 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001212 293.0
HKD1_k127_779244_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.079e-198 655.0
HKD1_k127_779244_30 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003755 282.0
HKD1_k127_779244_31 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000001398 261.0
HKD1_k127_779244_32 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000007673 265.0
HKD1_k127_779244_33 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000318 252.0
HKD1_k127_779244_34 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000003209 258.0
HKD1_k127_779244_35 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000002497 254.0
HKD1_k127_779244_36 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000003535 250.0
HKD1_k127_779244_37 Sigma-54 interaction domain K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000003933 261.0
HKD1_k127_779244_38 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000000000000000000000000000000000000000000000000394 232.0
HKD1_k127_779244_39 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000005827 235.0
HKD1_k127_779244_4 Ftsk_gamma K03466 - - 3.663e-198 644.0
HKD1_k127_779244_40 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000008788 224.0
HKD1_k127_779244_41 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000001356 224.0
HKD1_k127_779244_42 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000006706 210.0
HKD1_k127_779244_43 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000003099 209.0
HKD1_k127_779244_44 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000001376 223.0
HKD1_k127_779244_45 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000002596 204.0
HKD1_k127_779244_46 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000001679 187.0
HKD1_k127_779244_47 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000001652 191.0
HKD1_k127_779244_48 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000008373 187.0
HKD1_k127_779244_49 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000008364 172.0
HKD1_k127_779244_5 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 590.0
HKD1_k127_779244_50 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000002026 169.0
HKD1_k127_779244_51 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000002945 157.0
HKD1_k127_779244_52 thioesterase K07107 - - 0.00000000000000000000000000000000000003667 147.0
HKD1_k127_779244_53 SCO1/SenC - - - 0.0000000000000000000000000000000000000817 149.0
HKD1_k127_779244_54 galactose-6-phosphate isomerase activity K00568,K01808 - 2.1.1.222,2.1.1.64,5.3.1.6 0.0000000000000000000000000000000000005998 147.0
HKD1_k127_779244_55 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000001061 140.0
HKD1_k127_779244_56 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000005675 146.0
HKD1_k127_779244_57 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000006093 134.0
HKD1_k127_779244_58 Cytochrome c - - - 0.00000000000000000000000001713 115.0
HKD1_k127_779244_59 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000000008213 110.0
HKD1_k127_779244_6 Tannase and feruloyl esterase K21105 - 3.1.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 579.0
HKD1_k127_779244_60 PASTA domain K12132 - 2.7.11.1 0.00000000000000000000003776 108.0
HKD1_k127_779244_61 metal-dependent protease of the PAD1 JAB1 superfamily K21140 - 3.13.1.6 0.00000000000000000000005529 105.0
HKD1_k127_779244_62 helix_turn_helix, mercury resistance K13640 - - 0.0000000000000000000004579 105.0
HKD1_k127_779244_63 Chorismate mutase type II K04093 - 5.4.99.5 0.0000000000000000001971 93.0
HKD1_k127_779244_64 - - - - 0.0000000000000005953 89.0
HKD1_k127_779244_65 Outer membrane lipoprotein K05807 - - 0.000000000000003965 89.0
HKD1_k127_779244_66 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.0000000000002668 79.0
HKD1_k127_779244_67 Belongs to the HSP15 family K04762 - - 0.0000000000008754 74.0
HKD1_k127_779244_68 LysM domain K01185,K02030,K04043 - 3.2.1.17 0.00000003487 66.0
HKD1_k127_779244_69 - - - - 0.000001394 57.0
HKD1_k127_779244_7 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 536.0
HKD1_k127_779244_70 tpr domain protein - - - 0.000008907 59.0
HKD1_k127_779244_8 Pyrrolo-quinoline quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 519.0
HKD1_k127_779244_9 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 479.0
HKD1_k127_7810370_0 Insulinase (Peptidase family M16) K07263 - - 5.807e-208 680.0
HKD1_k127_7810370_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 480.0
HKD1_k127_7810370_10 - - - - 0.00000000000001805 84.0
HKD1_k127_7810370_11 - - - - 0.0000000000005821 76.0
HKD1_k127_7810370_12 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000004227 74.0
HKD1_k127_7810370_13 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.000000005492 60.0
HKD1_k127_7810370_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 351.0
HKD1_k127_7810370_3 Oxidoreductase molybdopterin binding domain K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001084 278.0
HKD1_k127_7810370_4 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001893 269.0
HKD1_k127_7810370_5 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000004046 164.0
HKD1_k127_7810370_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000002734 110.0
HKD1_k127_7810370_7 - - - - 0.0000000000000000000000007321 116.0
HKD1_k127_7810370_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000001609 98.0
HKD1_k127_7810370_9 Glyoxalase-like domain - - - 0.0000000000000000009571 98.0
HKD1_k127_7871652_0 Molecular chaperone. Has ATPase activity K04079 - - 8.034e-271 849.0
HKD1_k127_7871652_1 metallopeptidase activity - - - 4.261e-236 778.0
HKD1_k127_7871652_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000006042 224.0
HKD1_k127_7871652_3 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000001782 216.0
HKD1_k127_7871652_4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000004206 206.0
HKD1_k127_7871652_5 - - - - 0.000000000000000000000000001182 117.0
HKD1_k127_7871652_6 response regulator K02667 - - 0.0006075 50.0
HKD1_k127_7886312_0 TonB dependent receptor K16090 - - 7.841e-222 712.0
HKD1_k127_7886312_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019464,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045250,GO:0045252,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 627.0
HKD1_k127_7886312_10 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 396.0
HKD1_k127_7886312_11 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 370.0
HKD1_k127_7886312_12 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 334.0
HKD1_k127_7886312_13 Serine aminopeptidase, S33 K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 303.0
HKD1_k127_7886312_14 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 289.0
HKD1_k127_7886312_15 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 311.0
HKD1_k127_7886312_16 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 289.0
HKD1_k127_7886312_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 257.0
HKD1_k127_7886312_18 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002182 249.0
HKD1_k127_7886312_19 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000002364 222.0
HKD1_k127_7886312_2 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 575.0
HKD1_k127_7886312_20 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000004885 213.0
HKD1_k127_7886312_21 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000003531 214.0
HKD1_k127_7886312_22 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000001978 201.0
HKD1_k127_7886312_23 Uncharacterised protein family UPF0052 - - - 0.000000000000000000000000000000000000000000000000000003806 202.0
HKD1_k127_7886312_24 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000000000000000000006741 194.0
HKD1_k127_7886312_25 - - - - 0.0000000000000000000000000000000000000000001672 166.0
HKD1_k127_7886312_26 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000000000000000000731 153.0
HKD1_k127_7886312_27 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000008406 157.0
HKD1_k127_7886312_28 GAF domain - - - 0.000000000000000000000000000000000000004004 168.0
HKD1_k127_7886312_29 DinB family - - - 0.000000000000000000000000000000000000007102 153.0
HKD1_k127_7886312_3 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 526.0
HKD1_k127_7886312_30 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000000008074 151.0
HKD1_k127_7886312_31 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000005528 153.0
HKD1_k127_7886312_32 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000005543 130.0
HKD1_k127_7886312_33 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000199 126.0
HKD1_k127_7886312_34 TPM domain K06872 - - 0.00000000000000000000000001646 125.0
HKD1_k127_7886312_35 PFAM CBS domain containing protein - - - 0.0000000000000000000000005456 112.0
HKD1_k127_7886312_36 - - - - 0.000000000000000000001346 108.0
HKD1_k127_7886312_37 - - - - 0.0000000000000000001614 93.0
HKD1_k127_7886312_38 nucleotidyltransferase activity - - - 0.000000000000000004552 94.0
HKD1_k127_7886312_39 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000001256 87.0
HKD1_k127_7886312_4 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 515.0
HKD1_k127_7886312_40 Putative zinc-finger - - - 0.0000003405 61.0
HKD1_k127_7886312_41 gag-polyprotein putative aspartyl protease - - - 0.000001635 61.0
HKD1_k127_7886312_42 Transcriptional regulator PadR-like family - - - 0.00009573 49.0
HKD1_k127_7886312_43 Copper binding proteins, plastocyanin/azurin family - - - 0.0004188 49.0
HKD1_k127_7886312_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 502.0
HKD1_k127_7886312_6 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 473.0
HKD1_k127_7886312_7 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 438.0
HKD1_k127_7886312_8 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 402.0
HKD1_k127_7886312_9 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 390.0
HKD1_k127_7892432_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1106.0
HKD1_k127_7892432_1 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 3.247e-224 711.0
HKD1_k127_7892432_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000001899 120.0
HKD1_k127_7892432_11 - - - - 0.0000000000000000000001663 103.0
HKD1_k127_7892432_12 WHG domain - - - 0.00000000000000000000129 112.0
HKD1_k127_7892432_13 - - - - 0.00000000000001215 76.0
HKD1_k127_7892432_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 543.0
HKD1_k127_7892432_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 443.0
HKD1_k127_7892432_4 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 351.0
HKD1_k127_7892432_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008454 280.0
HKD1_k127_7892432_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000007906 248.0
HKD1_k127_7892432_7 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000003593 252.0
HKD1_k127_7892432_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000009771 159.0
HKD1_k127_7892432_9 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000007357 166.0
HKD1_k127_7896826_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 358.0
HKD1_k127_7896826_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000001228 218.0
HKD1_k127_7896826_2 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000002552 167.0
HKD1_k127_7896826_3 OmpA family K03640 - - 0.000000000000000000000000000000000009512 139.0
HKD1_k127_7896826_4 - - - - 0.00000000000000000000000000006067 127.0
HKD1_k127_7896826_5 MacB-like periplasmic core domain - - - 0.00000000000002182 79.0
HKD1_k127_7896826_6 Glutaredoxin-like domain (DUF836) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000002642 78.0
HKD1_k127_790331_0 Dehydrogenase K00117 - 1.1.5.2 7.809e-279 877.0
HKD1_k127_790331_1 Ankyrin repeats (many copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 315.0
HKD1_k127_7959813_0 DNA topological change - - - 1.551e-217 699.0
HKD1_k127_7959813_1 PQQ-like domain K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 614.0
HKD1_k127_7959813_10 G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 372.0
HKD1_k127_7959813_11 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 357.0
HKD1_k127_7959813_12 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 337.0
HKD1_k127_7959813_13 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 336.0
HKD1_k127_7959813_14 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 320.0
HKD1_k127_7959813_15 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006579 277.0
HKD1_k127_7959813_16 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000447 257.0
HKD1_k127_7959813_17 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000002353 251.0
HKD1_k127_7959813_18 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000322 224.0
HKD1_k127_7959813_19 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000304 209.0
HKD1_k127_7959813_2 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 536.0
HKD1_k127_7959813_20 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000008278 216.0
HKD1_k127_7959813_21 - - - - 0.00000000000000000000000000000000000000000000000000000003591 217.0
HKD1_k127_7959813_22 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000006415 211.0
HKD1_k127_7959813_23 PFAM von Willebrand factor type A K07114,K12511 - - 0.0000000000000000000000000000000000000000000000000000025 204.0
HKD1_k127_7959813_24 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000006276 197.0
HKD1_k127_7959813_25 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000001913 211.0
HKD1_k127_7959813_26 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.0000000000000000000000000000000000000000000000000002251 199.0
HKD1_k127_7959813_27 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000003945 200.0
HKD1_k127_7959813_28 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000003279 192.0
HKD1_k127_7959813_29 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000001817 181.0
HKD1_k127_7959813_3 flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 507.0
HKD1_k127_7959813_30 lactoylglutathione lyase activity K03088 - - 0.0000000000000000000000000000000000000000000004618 182.0
HKD1_k127_7959813_31 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000000000000002337 169.0
HKD1_k127_7959813_32 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000003263 158.0
HKD1_k127_7959813_33 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000000000000000000000000000002581 146.0
HKD1_k127_7959813_35 - - - - 0.0000000000000000000000000000000000002027 153.0
HKD1_k127_7959813_36 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000001109 161.0
HKD1_k127_7959813_37 - - - - 0.00000000000000000000000000000000001438 152.0
HKD1_k127_7959813_38 YXWGXW repeat (2 copies) - - - 0.000000000000000000000000000000004021 134.0
HKD1_k127_7959813_39 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000002257 131.0
HKD1_k127_7959813_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 485.0
HKD1_k127_7959813_40 Dehydrogenase K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 0.00000000000000000000001569 105.0
HKD1_k127_7959813_41 - - - - 0.0000000000000000000001722 106.0
HKD1_k127_7959813_43 AraC-like ligand binding domain - - - 0.0000000000000000004987 101.0
HKD1_k127_7959813_45 NIPSNAP - - - 0.000000000000004004 83.0
HKD1_k127_7959813_46 Cupin 2, conserved barrel domain protein - - - 0.000000000003411 76.0
HKD1_k127_7959813_48 Belongs to the ParB family K03497 - - 0.00000002965 65.0
HKD1_k127_7959813_49 peptidyl-tyrosine sulfation - - - 0.0000001224 65.0
HKD1_k127_7959813_5 SMP-30/Gluconolaconase/LRE-like region K13874,K14274 - 3.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 462.0
HKD1_k127_7959813_50 - - - - 0.0000803 56.0
HKD1_k127_7959813_51 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000488 51.0
HKD1_k127_7959813_6 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 459.0
HKD1_k127_7959813_7 3-keto-5-aminohexanoate cleavage protein K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 447.0
HKD1_k127_7959813_8 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 437.0
HKD1_k127_7959813_9 Belongs to the TPP enzyme family K01568,K04103 - 4.1.1.1,4.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 456.0
HKD1_k127_824375_0 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 556.0
HKD1_k127_824375_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 372.0
HKD1_k127_824375_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000005815 226.0
HKD1_k127_824375_3 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000000001387 158.0
HKD1_k127_824375_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000002511 92.0
HKD1_k127_824375_5 transglycosylase associated protein - - - 0.000000000000006419 78.0
HKD1_k127_824375_6 PFAM Integrase, catalytic - - - 0.00000000001761 66.0
HKD1_k127_826539_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 6.212e-251 779.0
HKD1_k127_826539_1 cellulose binding - - - 1.047e-223 706.0
HKD1_k127_826539_10 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 322.0
HKD1_k127_826539_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000203 268.0
HKD1_k127_826539_12 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000001928 260.0
HKD1_k127_826539_13 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002415 269.0
HKD1_k127_826539_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001989 252.0
HKD1_k127_826539_15 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000461 247.0
HKD1_k127_826539_16 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000002986 202.0
HKD1_k127_826539_17 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000008899 224.0
HKD1_k127_826539_18 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000002453 219.0
HKD1_k127_826539_19 TipAS antibiotic-recognition domain - - - 0.00000000000000000000000000000000000000000000000000005136 200.0
HKD1_k127_826539_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 2.382e-221 704.0
HKD1_k127_826539_20 - - - - 0.0000000000000000000000000000000000000000000000000000585 199.0
HKD1_k127_826539_21 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07671 GO:0000287,GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043167,GO:0043169,GO:0044110,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051704,GO:0071944 - 0.000000000000000000000000000000000000007915 154.0
HKD1_k127_826539_22 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000007515 142.0
HKD1_k127_826539_23 - - - - 0.00000000000000000000000000000000004368 144.0
HKD1_k127_826539_24 - - - - 0.0000000000000000000000000000002772 139.0
HKD1_k127_826539_25 - - - - 0.00000000000000000000000000243 121.0
HKD1_k127_826539_26 NAD(P)+ transhydrogenase (AB-specific) activity K00324 - 1.6.1.2 0.000000000000000000001453 108.0
HKD1_k127_826539_28 YceI-like domain - - - 0.0000000000000000001698 98.0
HKD1_k127_826539_29 phosphatidate phosphatase activity K19302 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.27 0.000000000000000001117 101.0
HKD1_k127_826539_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 546.0
HKD1_k127_826539_30 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000077 94.0
HKD1_k127_826539_31 - - - - 0.0000000000000002757 87.0
HKD1_k127_826539_32 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000006976 85.0
HKD1_k127_826539_33 Cytochrome c K17760 - 1.1.9.1 0.0000000000004524 76.0
HKD1_k127_826539_34 Surface antigen - - - 0.000000005181 68.0
HKD1_k127_826539_35 Outer membrane protein, OMP85 family K07277 - - 0.000005523 59.0
HKD1_k127_826539_36 Lipocalin-like domain - - - 0.0002038 53.0
HKD1_k127_826539_4 PFAM aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 564.0
HKD1_k127_826539_5 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 527.0
HKD1_k127_826539_6 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 513.0
HKD1_k127_826539_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 428.0
HKD1_k127_826539_8 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 371.0
HKD1_k127_826539_9 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 356.0
HKD1_k127_838040_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 625.0
HKD1_k127_838040_1 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 494.0
HKD1_k127_838040_10 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 374.0
HKD1_k127_838040_11 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 352.0
HKD1_k127_838040_12 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 329.0
HKD1_k127_838040_13 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 323.0
HKD1_k127_838040_14 Arginase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 326.0
HKD1_k127_838040_15 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 286.0
HKD1_k127_838040_16 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000398 276.0
HKD1_k127_838040_17 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002697 265.0
HKD1_k127_838040_18 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000004568 240.0
HKD1_k127_838040_19 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000001269 235.0
HKD1_k127_838040_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 438.0
HKD1_k127_838040_20 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000008089 186.0
HKD1_k127_838040_21 Belongs to the peptidase S11 family K01286,K07258,K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.4.16.4 0.00000000000000000000000000000000000000004422 171.0
HKD1_k127_838040_22 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000007624 158.0
HKD1_k127_838040_23 belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.000000000000000000000000000000000000001877 149.0
HKD1_k127_838040_24 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000001612 139.0
HKD1_k127_838040_25 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000003473 132.0
HKD1_k127_838040_26 - - - - 0.000000000000000000000000004589 116.0
HKD1_k127_838040_27 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000001649 123.0
HKD1_k127_838040_28 YXWGXW repeat (2 copies) - - - 0.000000000000000000000000476 111.0
HKD1_k127_838040_29 DUF167 K09131 - - 0.0000000000000000000001118 103.0
HKD1_k127_838040_3 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 427.0
HKD1_k127_838040_30 O-methyltransferase - - - 0.000000000000000000001491 110.0
HKD1_k127_838040_31 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000002571 95.0
HKD1_k127_838040_32 Transcriptional regulatory protein, C terminal K07671 - - 0.000000000000003279 80.0
HKD1_k127_838040_33 oxidoreductase activity - - - 0.00000000000004591 85.0
HKD1_k127_838040_35 response regulator K07714 - - 0.00000001819 61.0
HKD1_k127_838040_36 - - - - 0.0000008616 54.0
HKD1_k127_838040_37 collagen metabolic process K07004,K08677,K10440,K14274,K21449 - - 0.000001984 53.0
HKD1_k127_838040_38 Tetratricopeptide TPR_2 repeat protein - - - 0.000007634 58.0
HKD1_k127_838040_39 methyltransferase - - - 0.00006275 53.0
HKD1_k127_838040_4 PFAM Peptidase M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 430.0
HKD1_k127_838040_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 414.0
HKD1_k127_838040_6 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671,K22345 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 404.0
HKD1_k127_838040_7 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 385.0
HKD1_k127_838040_8 Cys/Met metabolism PLP-dependent enzyme K01758 GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 4.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 372.0
HKD1_k127_838040_9 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 380.0
HKD1_k127_882171_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 5.061e-284 904.0
HKD1_k127_882171_1 DNA topological change K03168 - 5.99.1.2 2.813e-201 672.0
HKD1_k127_882171_10 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000004088 262.0
HKD1_k127_882171_11 response regulator, receiver K02483,K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000002167 241.0
HKD1_k127_882171_12 AI-2E family transporter - - - 0.00000000000000000000000000000000000003075 163.0
HKD1_k127_882171_13 ankyrin 3, node of Ranvier (ankyrin G) - - - 0.00000000000000000000005601 114.0
HKD1_k127_882171_14 NMT1-like family K07080 - - 0.0000003042 64.0
HKD1_k127_882171_15 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0002845 44.0
HKD1_k127_882171_2 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009306 573.0
HKD1_k127_882171_3 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 557.0
HKD1_k127_882171_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 545.0
HKD1_k127_882171_5 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 449.0
HKD1_k127_882171_6 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 461.0
HKD1_k127_882171_7 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 443.0
HKD1_k127_882171_8 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 409.0
HKD1_k127_882171_9 Bile acid K03453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006473 266.0
HKD1_k127_904731_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.245e-200 640.0
HKD1_k127_904731_1 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002759 275.0
HKD1_k127_904731_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002585 229.0
HKD1_k127_904731_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000762 190.0
HKD1_k127_904731_4 - - - - 0.00000000000000000000000000000000000000002025 174.0
HKD1_k127_904731_5 - - - - 0.0000000000000542 81.0