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Overview

ID MAG01703
Name HKD1_bin.14
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Steroidobacterales
Family Steroidobacteraceae
Genus RPQJ01
Species
Assembly information
Completeness (%) 86.54
Contamination (%) 5.1
GC content (%) 68.0
N50 (bp) 10,017
Genome size (bp) 3,105,392

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3003

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1002480_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 573.0
HKD1_k127_1011909_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.916e-214 690.0
HKD1_k127_1011909_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 601.0
HKD1_k127_1011909_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 588.0
HKD1_k127_1011909_3 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 298.0
HKD1_k127_1011909_4 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006006 278.0
HKD1_k127_1011909_5 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000005626 181.0
HKD1_k127_1011909_6 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000001138 70.0
HKD1_k127_1022970_0 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 328.0
HKD1_k127_1022970_1 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000852 249.0
HKD1_k127_1022970_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000001036 186.0
HKD1_k127_1022970_3 protein conserved in bacteria - - - 0.00000000000000000000000000000001791 132.0
HKD1_k127_1022970_4 Predicted integral membrane protein (DUF2282) - - - 0.00000000000000000000003572 104.0
HKD1_k127_1024438_0 response regulator K02481,K10941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 617.0
HKD1_k127_1024438_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 594.0
HKD1_k127_1024438_2 COG0457 FOG TPR repeat - - - 0.00000000000000002409 86.0
HKD1_k127_1026986_0 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001462 279.0
HKD1_k127_1026986_1 HTH domain - - - 0.000000000000000000000000000000000000000000000000003882 188.0
HKD1_k127_1026986_2 transglycosylase associated protein - - - 0.00000000000000000000000001488 109.0
HKD1_k127_1028549_0 III protein, CoA-transferase family K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 526.0
HKD1_k127_1028549_1 aminotransferase K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 389.0
HKD1_k127_1028549_2 Belongs to the bacterial solute-binding protein 9 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 353.0
HKD1_k127_1028549_3 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002627 276.0
HKD1_k127_1028549_4 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005196 247.0
HKD1_k127_1034985_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 4.983e-213 669.0
HKD1_k127_1034985_1 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 492.0
HKD1_k127_1034985_2 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 395.0
HKD1_k127_1034985_3 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001038 238.0
HKD1_k127_1034985_4 transcriptional regulator K07506 - - 0.00000000000000000000000000000000000000000000000000000000000002975 225.0
HKD1_k127_1035540_0 COG2015 Alkyl sulfatase and related hydrolases K01138 - - 3.053e-306 952.0
HKD1_k127_1035540_1 arylsulfatase A K01130 - 3.1.6.1 3.63e-283 876.0
HKD1_k127_1035540_10 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000002006 102.0
HKD1_k127_1035540_2 GMC oxidoreductase K03333 - 1.1.3.6 2.404e-225 709.0
HKD1_k127_1035540_3 PFAM thiamine pyrophosphate protein TPP binding domain protein - - - 5.903e-212 672.0
HKD1_k127_1035540_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 265.0
HKD1_k127_1035540_5 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000001648 222.0
HKD1_k127_1035540_6 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000006428 202.0
HKD1_k127_1035540_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000002722 171.0
HKD1_k127_1035540_8 Sh3 type 3 domain protein K01361 - 3.4.21.96 0.0000000000000000000000000000000000000001032 162.0
HKD1_k127_1035540_9 YMGG-like Gly-zipper - - - 0.0000000000000000000000000000004502 130.0
HKD1_k127_1040565_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 371.0
HKD1_k127_1040565_1 FAD binding domain K03391,K05712 - 1.14.13.127,1.14.13.50 0.0000000000000000000004925 102.0
HKD1_k127_1040842_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1220.0
HKD1_k127_1040842_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 381.0
HKD1_k127_1040842_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006959 262.0
HKD1_k127_1040842_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000001415 232.0
HKD1_k127_1040842_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000001606 93.0
HKD1_k127_1042377_0 COG0183 Acetyl-CoA acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 590.0
HKD1_k127_1042377_1 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 580.0
HKD1_k127_1042377_2 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000000000002473 216.0
HKD1_k127_1042377_3 Mycofactocin system - - - 0.000000000000000000002336 97.0
HKD1_k127_1042377_4 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000144 64.0
HKD1_k127_1060798_0 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 7.934e-277 876.0
HKD1_k127_1060798_1 Aminopeptidase puromycin sensitive - - - 1.062e-234 777.0
HKD1_k127_1060798_10 Peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000003553 226.0
HKD1_k127_1060798_11 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000000489 181.0
HKD1_k127_1060798_12 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000025 159.0
HKD1_k127_1060798_13 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000006968 115.0
HKD1_k127_1060798_14 Alpha beta hydrolase - - - 0.00000000000001639 78.0
HKD1_k127_1060798_15 NERD domain protein - - - 0.000000003418 69.0
HKD1_k127_1060798_2 PFAM amidohydrolase K01464,K01466 - 3.5.2.2,3.5.2.5 1.467e-220 693.0
HKD1_k127_1060798_3 peptidase M20 - - - 1.422e-211 666.0
HKD1_k127_1060798_4 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 478.0
HKD1_k127_1060798_5 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 459.0
HKD1_k127_1060798_6 NADP-dependent oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 339.0
HKD1_k127_1060798_7 Preprotein translocase subunit TatD K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 320.0
HKD1_k127_1060798_8 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 297.0
HKD1_k127_1060798_9 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000138 252.0
HKD1_k127_1065745_0 Sugar ABC transporter permease K10109,K15770,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 503.0
HKD1_k127_1072608_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 317.0
HKD1_k127_1072608_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000001476 179.0
HKD1_k127_1072608_2 AntiSigma factor - - - 0.000000000000000000000000000006936 130.0
HKD1_k127_1072608_4 Alpha/beta hydrolase family - - - 0.0006033 49.0
HKD1_k127_1072954_0 PAC sensor-containing diguanylate cyclase phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 338.0
HKD1_k127_1075920_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1223.0
HKD1_k127_1075920_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 4.606e-306 951.0
HKD1_k127_1075920_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 505.0
HKD1_k127_1075920_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 485.0
HKD1_k127_1075920_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 485.0
HKD1_k127_1075920_5 CoA-transferase family III K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 461.0
HKD1_k127_1075920_6 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000000000000000001083 174.0
HKD1_k127_1075920_7 cyclic nucleotide binding K10914 - - 0.000000000000000000000000002862 117.0
HKD1_k127_1075920_8 Asparaginase K01424 - 3.5.1.1 0.0000000000000135 73.0
HKD1_k127_1085781_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.811e-226 717.0
HKD1_k127_1085781_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 522.0
HKD1_k127_1085781_2 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 427.0
HKD1_k127_1085781_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002641 276.0
HKD1_k127_1085781_4 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000001844 169.0
HKD1_k127_1085781_5 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.00000003593 61.0
HKD1_k127_1095373_0 Diguanylate cyclase - - - 4.073e-196 631.0
HKD1_k127_1097617_0 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 604.0
HKD1_k127_1097617_1 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000001194 227.0
HKD1_k127_1097617_2 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000007579 77.0
HKD1_k127_1097617_3 FCD - - - 0.0000000001594 68.0
HKD1_k127_1099128_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 445.0
HKD1_k127_1099128_1 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000001189 232.0
HKD1_k127_1099128_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.00000000000000000000000000000000000000000000000006504 184.0
HKD1_k127_1099128_3 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000007746 127.0
HKD1_k127_1102374_0 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 317.0
HKD1_k127_1102374_1 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 288.0
HKD1_k127_1102374_2 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009956 278.0
HKD1_k127_1102374_3 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000001825 247.0
HKD1_k127_1102374_4 SMART PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000004648 225.0
HKD1_k127_1102374_5 Thioesterase superfamily K07107 - - 0.0000000000000000000000000000000000000002365 156.0
HKD1_k127_1107063_0 permease K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000001641 248.0
HKD1_k127_1107063_1 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000008296 214.0
HKD1_k127_1107063_2 Permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000002508 201.0
HKD1_k127_1107063_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000007458 184.0
HKD1_k127_1107063_4 pfam rdd - - - 0.00000000000000000000000000000000000007198 146.0
HKD1_k127_1107063_5 Cytochrome C' - - - 0.000000000000000000000000393 109.0
HKD1_k127_1107144_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009665 300.0
HKD1_k127_1107144_1 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008873 277.0
HKD1_k127_1107144_2 spectrin binding - - - 0.000000000000000000000000005133 124.0
HKD1_k127_1107510_0 COG3104 Dipeptide tripeptide permease K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 616.0
HKD1_k127_1107510_1 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 437.0
HKD1_k127_1113765_0 GTP-binding protein TypA K06207 - - 1.465e-269 838.0
HKD1_k127_1113765_1 Putative diguanylate phosphodiesterase K03320 - - 0.0000000000000000000000000000009978 123.0
HKD1_k127_1130670_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 571.0
HKD1_k127_1130670_1 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009699 364.0
HKD1_k127_1130994_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 355.0
HKD1_k127_1130994_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000006351 216.0
HKD1_k127_1130994_2 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000002516 177.0
HKD1_k127_1152246_0 DEAD DEAH box helicase K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 483.0
HKD1_k127_1152246_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000004646 235.0
HKD1_k127_1152246_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine - - - 0.0000000000000000000000000000000000000000001689 159.0
HKD1_k127_1160523_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1117.0
HKD1_k127_1160523_1 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 384.0
HKD1_k127_1160523_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002919 280.0
HKD1_k127_1160523_3 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006438 268.0
HKD1_k127_1160523_4 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005179 256.0
HKD1_k127_1160523_5 WHG domain - - - 0.0000000000000000000000000000000000000000000000000000000494 203.0
HKD1_k127_1160523_6 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000004265 193.0
HKD1_k127_1162416_0 PFAM beta-lactamase domain protein K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 520.0
HKD1_k127_1176809_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 485.0
HKD1_k127_1176809_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 356.0
HKD1_k127_1176809_2 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000001293 211.0
HKD1_k127_1176809_3 Exopolysaccharide synthesis, ExoD - - - 0.0000000000000000000000000000000000000000000003305 180.0
HKD1_k127_1176809_4 Protein of unknown function (DUF2505) - - - 0.0003502 49.0
HKD1_k127_1187062_0 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 531.0
HKD1_k127_1187062_1 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 431.0
HKD1_k127_1187062_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000108 236.0
HKD1_k127_1187062_11 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000119 222.0
HKD1_k127_1187062_12 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.0000000000000000000000000000000000000000000000000000000000009295 223.0
HKD1_k127_1187062_13 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001867 192.0
HKD1_k127_1187062_14 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000006395 119.0
HKD1_k127_1187062_15 modulator of DNA gyrase K03568 - - 0.0000000000000004525 77.0
HKD1_k127_1187062_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 409.0
HKD1_k127_1187062_3 ABC transporter substrate-binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 379.0
HKD1_k127_1187062_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 360.0
HKD1_k127_1187062_5 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 323.0
HKD1_k127_1187062_6 Type II secretory pathway component ExeA K02450,K12283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 313.0
HKD1_k127_1187062_7 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006188 280.0
HKD1_k127_1187062_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003583 236.0
HKD1_k127_1187062_9 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000001029 235.0
HKD1_k127_1189544_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 454.0
HKD1_k127_1189544_1 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 313.0
HKD1_k127_1189544_2 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 296.0
HKD1_k127_1189544_3 With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P K04568 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016746,GO:0016755,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052868,GO:0071704,GO:0071915,GO:0072580,GO:0072581,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 295.0
HKD1_k127_1189544_4 Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000007833 257.0
HKD1_k127_1189544_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000000000000000001218 207.0
HKD1_k127_1189544_6 SCO1/SenC K07152 - - 0.00000000000000000000000000000000008808 141.0
HKD1_k127_1200940_0 synthesis repressor, PhaR - - - 0.00000000000000000000000000000000000007277 152.0
HKD1_k127_1200940_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K10778 - 2.1.1.63 0.0000000000000000000000000000001841 127.0
HKD1_k127_1200940_2 N-terminal half of MaoC dehydratase - - - 0.00000000000000000007823 91.0
HKD1_k127_1202477_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 598.0
HKD1_k127_1202477_1 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 448.0
HKD1_k127_1202477_2 KR domain K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000782 235.0
HKD1_k127_1202477_3 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000297 152.0
HKD1_k127_1204444_0 Belongs to the TPP enzyme family K03852 - 2.3.3.15 2.823e-267 842.0
HKD1_k127_1204444_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.225e-245 764.0
HKD1_k127_1204444_2 AMP-binding enzyme C-terminal domain K00666 - - 2.008e-239 753.0
HKD1_k127_1204444_3 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 421.0
HKD1_k127_1204444_4 Flagellar basal body rod K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002897 272.0
HKD1_k127_1204444_5 membrane protein domain - - - 0.0000000000000000000000000000000000000000000000000001301 188.0
HKD1_k127_1204444_6 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000007869 171.0
HKD1_k127_1204444_7 - - - - 0.000000000000253 72.0
HKD1_k127_1207316_0 belongs to the aldehyde dehydrogenase family K00128,K19700 - 1.2.1.3,1.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 495.0
HKD1_k127_1207316_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000008881 133.0
HKD1_k127_1209292_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.232e-244 773.0
HKD1_k127_1209292_1 Bacterial protein of unknown function (DUF885) - - - 3.452e-221 700.0
HKD1_k127_1209292_2 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 394.0
HKD1_k127_1209292_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009898 246.0
HKD1_k127_1209292_4 conserved protein UCP033924 precursor - - - 0.0000000000000009321 82.0
HKD1_k127_1209738_0 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000442 244.0
HKD1_k127_1209738_1 O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000001837 151.0
HKD1_k127_121820_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004001 244.0
HKD1_k127_121820_1 - - - - 0.000000000000000001038 93.0
HKD1_k127_121820_2 cheY-homologous receiver domain - - - 0.00000000005368 70.0
HKD1_k127_1228301_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.242e-228 734.0
HKD1_k127_1228301_1 receptor - - - 1.239e-204 656.0
HKD1_k127_1228301_10 - - - - 0.0001619 49.0
HKD1_k127_1228301_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 556.0
HKD1_k127_1228301_3 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 442.0
HKD1_k127_1228301_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 433.0
HKD1_k127_1228301_5 COG0303 Molybdopterin biosynthesis enzyme K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 369.0
HKD1_k127_1228301_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000001463 209.0
HKD1_k127_1228301_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000007368 199.0
HKD1_k127_1228301_8 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000008993 100.0
HKD1_k127_1228301_9 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000003439 84.0
HKD1_k127_122959_0 FimV N-terminal domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 467.0
HKD1_k127_122959_1 abc transporter, permease K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008037 361.0
HKD1_k127_122959_2 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002593 282.0
HKD1_k127_122959_3 ABC-type molybdate transport system periplasmic component K02020 GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0015689,GO:0015698,GO:0030973,GO:0043167,GO:0043168,GO:0051179,GO:0051234,GO:1901359 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001504 252.0
HKD1_k127_122959_4 Transcriptional regulator K02019 - - 0.00000000000000000000000000000000000000000000000000000000000000000002297 241.0
HKD1_k127_122959_5 phosphate transport system permease K02038 - - 0.0000000000000005283 78.0
HKD1_k127_123283_0 Nickel-dependent hydrogenase K05922,K06281 - 1.12.5.1,1.12.99.6 2.449e-307 949.0
HKD1_k127_123283_1 PFAM Cysteine-rich - - - 2.638e-224 704.0
HKD1_k127_123283_10 Hydrogenase expression formation protein K03605 - - 0.000000000000000000000000000000000000001067 153.0
HKD1_k127_123283_11 transcriptional - - - 0.00000000000000000000002096 113.0
HKD1_k127_123283_12 Nodulation protein S (NodS) - - - 0.0000000000000000000001072 108.0
HKD1_k127_123283_2 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 541.0
HKD1_k127_123283_3 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 523.0
HKD1_k127_123283_4 Hydrogenase (NiFe) small subunit HydA K05927 - 1.12.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 508.0
HKD1_k127_123283_5 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 391.0
HKD1_k127_123283_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002491 262.0
HKD1_k127_123283_7 Glycine cleavage H-protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000002913 225.0
HKD1_k127_123283_8 nitrate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000007505 222.0
HKD1_k127_123283_9 - - - - 0.00000000000000000000000000000000000000001138 164.0
HKD1_k127_1241075_0 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 444.0
HKD1_k127_1241075_1 Na( )-dependent transporter - - - 0.00000000000000000000000000000004142 136.0
HKD1_k127_1251349_0 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 322.0
HKD1_k127_1251349_1 (ABC) transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006443 294.0
HKD1_k127_1251349_2 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000103 251.0
HKD1_k127_1251349_3 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000002144 194.0
HKD1_k127_1251349_4 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000001653 153.0
HKD1_k127_1251349_5 MlaD protein K02067 - - 0.00000000000000000000000000000000001204 149.0
HKD1_k127_1251349_6 transport system, auxiliary component K18480 - - 0.00000000000004438 81.0
HKD1_k127_1279289_0 2,4-dienoyl-coa reductase K00219 - 1.3.1.34 0.0 1043.0
HKD1_k127_1279289_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 485.0
HKD1_k127_1279289_2 phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 447.0
HKD1_k127_1279289_3 Periplasmic solute binding protein K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 364.0
HKD1_k127_1279289_4 signal transduction protein with a C-terminal ATPase domain K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 332.0
HKD1_k127_1279289_5 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 309.0
HKD1_k127_1279289_6 ABC-3 protein K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003199 288.0
HKD1_k127_1279289_7 CBS domain - - - 0.000000000000000642 87.0
HKD1_k127_1279289_8 Protein of unknown function DUF47 K07220 - - 0.0000000004453 61.0
HKD1_k127_1279507_0 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004294 247.0
HKD1_k127_1279507_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000001324 186.0
HKD1_k127_1279507_2 PFAM toluene tolerance family protein K07323 - - 0.000000000000000000000000000000000000000000001062 173.0
HKD1_k127_1279507_3 Furin-like repeats - - - 0.0000003189 63.0
HKD1_k127_1279507_4 PFAM glycosyl transferase family 2 K00721 - 2.4.1.83 0.00002038 50.0
HKD1_k127_1294469_0 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000003249 232.0
HKD1_k127_1294469_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000004727 167.0
HKD1_k127_1294469_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000004064 146.0
HKD1_k127_1294469_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000003748 104.0
HKD1_k127_1298947_0 WD40-like Beta Propeller Repeat - - - 0.0 1177.0
HKD1_k127_1298947_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 9.499e-241 753.0
HKD1_k127_1298947_10 Transcriptional regulator K02624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 319.0
HKD1_k127_1298947_11 Pseudouridine synthase K06175 - 5.4.99.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 310.0
HKD1_k127_1298947_12 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 306.0
HKD1_k127_1298947_13 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005429 279.0
HKD1_k127_1298947_14 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000003356 215.0
HKD1_k127_1298947_15 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.0000000000000000000000000000000000000000000004494 169.0
HKD1_k127_1298947_16 proteolysis - - - 0.0000000000000000000000000000000000000000003597 170.0
HKD1_k127_1298947_17 DNA-templated transcription, initiation K03088,K03091 - - 0.0000000000000000000000000000000004892 138.0
HKD1_k127_1298947_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 8.968e-237 737.0
HKD1_k127_1298947_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 7.157e-214 672.0
HKD1_k127_1298947_4 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 544.0
HKD1_k127_1298947_5 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 456.0
HKD1_k127_1298947_6 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 431.0
HKD1_k127_1298947_7 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 397.0
HKD1_k127_1298947_8 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 329.0
HKD1_k127_1298947_9 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009885 345.0
HKD1_k127_1316016_0 small GTP-binding protein K02355 - - 7.173e-297 924.0
HKD1_k127_1316016_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 360.0
HKD1_k127_1316016_2 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 301.0
HKD1_k127_1316016_3 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000001842 188.0
HKD1_k127_1316016_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000003677 175.0
HKD1_k127_1324930_0 Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 601.0
HKD1_k127_1324930_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 576.0
HKD1_k127_1324930_10 Diguanylate cyclase K21023 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 344.0
HKD1_k127_1324930_11 LysR substrate binding domain K18900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 316.0
HKD1_k127_1324930_12 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 297.0
HKD1_k127_1324930_13 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K01802,K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000001028 203.0
HKD1_k127_1324930_14 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000000000000000007825 191.0
HKD1_k127_1324930_15 Auxin binding protein - - - 0.000000000000000000000000000000000000000000000001474 177.0
HKD1_k127_1324930_16 Uncharacterized ACR, COG1993 - - - 0.000000000000000000000000000000000000008503 154.0
HKD1_k127_1324930_17 Methyltransferase domain - - - 0.0000000000000000000000000000002229 137.0
HKD1_k127_1324930_18 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000003456 118.0
HKD1_k127_1324930_19 PFAM peptidase M61 - - - 0.000000000000000000000000006816 120.0
HKD1_k127_1324930_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 492.0
HKD1_k127_1324930_20 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000008148 118.0
HKD1_k127_1324930_21 - - - - 0.000000000000000000001301 101.0
HKD1_k127_1324930_22 - - - - 0.000000000000000004031 88.0
HKD1_k127_1324930_23 Diacylglycerol kinase K19302 - 3.6.1.27 0.0000000000001401 84.0
HKD1_k127_1324930_3 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 425.0
HKD1_k127_1324930_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009026 401.0
HKD1_k127_1324930_5 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 361.0
HKD1_k127_1324930_6 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000906 353.0
HKD1_k127_1324930_7 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 357.0
HKD1_k127_1324930_8 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 339.0
HKD1_k127_1324930_9 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 327.0
HKD1_k127_1326663_0 Lytic murein transglycosylase K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 610.0
HKD1_k127_1326663_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 524.0
HKD1_k127_1326663_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 372.0
HKD1_k127_1326663_3 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 349.0
HKD1_k127_1326663_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000002248 200.0
HKD1_k127_1326663_5 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.0000000000000000000000000000000000000000000000000002104 200.0
HKD1_k127_1326663_6 cdp-diacylglycerol--glycerol-3-phosphate - - - 0.000000000000000000000000000000000000000005052 163.0
HKD1_k127_1326663_7 - - - - 0.0000000000000000000000000000000000000001429 157.0
HKD1_k127_1368921_0 AcrB/AcrD/AcrF family - - - 1.337e-294 914.0
HKD1_k127_1368921_1 serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 381.0
HKD1_k127_1368921_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 348.0
HKD1_k127_1368921_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000003263 188.0
HKD1_k127_1368921_4 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000001286 180.0
HKD1_k127_1368921_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000009872 151.0
HKD1_k127_1368921_6 Putative zinc-finger - - - 0.0000000000000417 81.0
HKD1_k127_1368921_7 - - - - 0.0000007465 57.0
HKD1_k127_1387837_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 533.0
HKD1_k127_1387837_1 ThiJ/PfpI family-like K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000004824 220.0
HKD1_k127_1387837_2 Protein of unknown function (DUF1203) - - - 0.00000000000000000000000000000000000000000004428 165.0
HKD1_k127_1454145_0 Enoyl-CoA hydratase/isomerase - - - 1.752e-202 651.0
HKD1_k127_1454145_1 PFAM Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004586 265.0
HKD1_k127_1454145_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002229 252.0
HKD1_k127_1454145_3 MTH538 TIR-like domain (DUF1863) - - - 0.00000000000000006381 86.0
HKD1_k127_1454145_4 cytochrome - - - 0.0003759 47.0
HKD1_k127_1456263_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 4.305e-274 865.0
HKD1_k127_1456263_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000001457 230.0
HKD1_k127_1479122_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.648e-257 809.0
HKD1_k127_1479122_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 585.0
HKD1_k127_1479122_10 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000004026 206.0
HKD1_k127_1479122_11 Required for insertion of 4Fe-4S clusters K15724 - - 0.00000000000000000000000000000000000000000000000000003458 189.0
HKD1_k127_1479122_12 Protein of unknown function, DUF484 - - - 0.000000000000000000000000000000000000006717 158.0
HKD1_k127_1479122_14 - - - - 0.000000000000514 78.0
HKD1_k127_1479122_2 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 502.0
HKD1_k127_1479122_3 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 410.0
HKD1_k127_1479122_4 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 341.0
HKD1_k127_1479122_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 324.0
HKD1_k127_1479122_6 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001818 241.0
HKD1_k127_1479122_7 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000697 230.0
HKD1_k127_1479122_8 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000003357 211.0
HKD1_k127_1479122_9 - - - - 0.00000000000000000000000000000000000000000000000000000003836 219.0
HKD1_k127_149226_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 472.0
HKD1_k127_149226_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 342.0
HKD1_k127_149226_2 Belongs to the UPF0758 family K03630 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 297.0
HKD1_k127_149226_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005313 273.0
HKD1_k127_149226_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000006041 247.0
HKD1_k127_149226_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000001797 214.0
HKD1_k127_149226_6 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000002017 128.0
HKD1_k127_149226_7 there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc K02913 - - 0.00000000000000000007511 89.0
HKD1_k127_1522670_0 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 422.0
HKD1_k127_1522670_1 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 295.0
HKD1_k127_1522670_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 291.0
HKD1_k127_1522670_3 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003732 241.0
HKD1_k127_1522670_4 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000000000005889 198.0
HKD1_k127_1522670_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000005218 158.0
HKD1_k127_1522670_6 Acetoacetate decarboxylase (ADC) - - - 0.000000000000000000000000000009856 129.0
HKD1_k127_1522670_7 Isochorismatase family - - - 0.0000000000000000000003048 113.0
HKD1_k127_1522670_8 3,4-dihydroxyphenylacetate 2,3-dioxygenase K00455 - 1.13.11.15 0.000000000000000003267 84.0
HKD1_k127_1534346_0 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 6.278e-274 853.0
HKD1_k127_1534346_1 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 392.0
HKD1_k127_1534346_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000137 256.0
HKD1_k127_1534346_3 Arylsulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001486 256.0
HKD1_k127_1534346_4 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000289 242.0
HKD1_k127_1534346_5 Rhodanese domain protein - - - 0.000000000000000000000000000000000000000000001264 169.0
HKD1_k127_153852_0 TonB dependent receptor K02014 - - 9.602e-273 865.0
HKD1_k127_153852_1 Glycosyl hydrolases family 15 - - - 5.346e-222 705.0
HKD1_k127_153852_10 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007887 254.0
HKD1_k127_153852_11 Phospholipase D. Active site motifs. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003973 259.0
HKD1_k127_153852_12 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000003843 234.0
HKD1_k127_153852_13 PFAM Inositol monophosphatase K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.0000000000000000000000000000000000000000000000000000000000002453 226.0
HKD1_k127_153852_14 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000006954 192.0
HKD1_k127_153852_15 Histidine kinase K05962 - 2.7.13.1 0.00000000000000000000000000000000000000000000000000748 198.0
HKD1_k127_153852_16 - - - - 0.00000000000000000000000000000000000000002856 159.0
HKD1_k127_153852_17 GEPR COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000001213 141.0
HKD1_k127_153852_18 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000000004778 117.0
HKD1_k127_153852_19 SCP-2 sterol transfer family - - - 0.00000000000000000000000003903 115.0
HKD1_k127_153852_2 to Mus musculus sphingosine-1-phosphate lyase Sgpl1 SWALL O54955 (EMBL AF036894) (568 aa) fasta scores E() K01634 - 4.1.2.27 1.012e-221 695.0
HKD1_k127_153852_20 response regulator - - - 0.000000000000000000002058 98.0
HKD1_k127_153852_21 BON domain - - - 0.00000000000000002706 86.0
HKD1_k127_153852_3 FGGY family of carbohydrate kinase, N-terminal domain protein K00854 - 2.7.1.17 2.797e-220 694.0
HKD1_k127_153852_4 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 2.717e-199 638.0
HKD1_k127_153852_5 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 586.0
HKD1_k127_153852_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819,K09251 - 2.6.1.13,2.6.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 346.0
HKD1_k127_153852_7 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 331.0
HKD1_k127_153852_8 Peptidase m28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 284.0
HKD1_k127_153852_9 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002358 270.0
HKD1_k127_1605694_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 293.0
HKD1_k127_1605694_1 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002628 211.0
HKD1_k127_1605694_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000246 166.0
HKD1_k127_16194_0 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 523.0
HKD1_k127_16194_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000006856 198.0
HKD1_k127_16194_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000002152 110.0
HKD1_k127_16194_3 TIGRFAM Cytochrome c-type biogenesis protein CcmI K02200 - - 0.0000000001871 68.0
HKD1_k127_162931_0 COG3209 Rhs family protein - - - 6.515e-195 631.0
HKD1_k127_162931_1 Phenylalanine-4-hydroxylase K00500 - 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 487.0
HKD1_k127_162931_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 473.0
HKD1_k127_162931_3 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 376.0
HKD1_k127_162931_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 314.0
HKD1_k127_162931_5 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 288.0
HKD1_k127_162931_6 Cellulose biosynthesis protein BcsQ - - - 0.000000000000000000000000000000000000000000000000000000000000002658 225.0
HKD1_k127_162931_7 Beta-lactamase class C - - - 0.00000000000000000000000000000000000000005436 169.0
HKD1_k127_162931_8 PFAM Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000002686 153.0
HKD1_k127_162931_9 - - - - 0.00000000000000000000000609 106.0
HKD1_k127_169262_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 599.0
HKD1_k127_169262_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 406.0
HKD1_k127_169262_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000007826 70.0
HKD1_k127_171046_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1225.0
HKD1_k127_171046_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1059.0
HKD1_k127_171046_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000007163 218.0
HKD1_k127_171046_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000003647 214.0
HKD1_k127_173190_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1039.0
HKD1_k127_173190_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 1.16e-307 953.0
HKD1_k127_173190_10 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002282 261.0
HKD1_k127_173190_11 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001026 257.0
HKD1_k127_173190_12 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000874 196.0
HKD1_k127_173190_13 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000003898 141.0
HKD1_k127_173190_14 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000005795 84.0
HKD1_k127_173190_15 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.00000000000000001249 85.0
HKD1_k127_173190_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 8.384e-266 842.0
HKD1_k127_173190_3 Cysteine-rich domain - - - 2.464e-204 645.0
HKD1_k127_173190_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 486.0
HKD1_k127_173190_5 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 409.0
HKD1_k127_173190_6 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 358.0
HKD1_k127_173190_7 COG2202 FOG PAS PAC domain K21025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 311.0
HKD1_k127_173190_8 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 300.0
HKD1_k127_173190_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 290.0
HKD1_k127_1767799_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit - - - 1.842e-262 824.0
HKD1_k127_1767799_1 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 455.0
HKD1_k127_1767799_2 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 384.0
HKD1_k127_1767799_3 hydrogenase 4 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002698 261.0
HKD1_k127_1767799_4 Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain K00101,K15054 - 1.1.2.3,1.1.99.31 0.0000000000000000000000000000000000000000000000000009914 186.0
HKD1_k127_1767799_5 PFAM CopG domain protein DNA-binding domain protein - - - 0.00000000000000008374 82.0
HKD1_k127_1931459_0 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 466.0
HKD1_k127_1931459_1 TIGRFAM ABC exporter ATP-binding subunit, DevA family K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 387.0
HKD1_k127_1931459_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000005911 237.0
HKD1_k127_1931459_3 Patatin-like phospholipase - - - 0.000000003035 63.0
HKD1_k127_19721_0 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 436.0
HKD1_k127_19721_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 430.0
HKD1_k127_19721_2 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 357.0
HKD1_k127_19721_3 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06136,K06137,K06138 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 319.0
HKD1_k127_19721_4 Fad dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 322.0
HKD1_k127_19721_5 Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 303.0
HKD1_k127_19721_6 signal peptide protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 301.0
HKD1_k127_19721_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000003183 90.0
HKD1_k127_19721_9 - - - - 0.0000000000006362 80.0
HKD1_k127_197835_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.187e-233 737.0
HKD1_k127_197835_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.206e-223 714.0
HKD1_k127_197835_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 476.0
HKD1_k127_197835_3 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000001483 203.0
HKD1_k127_197835_4 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.000000000000000000000000000000000000000000000000231 184.0
HKD1_k127_197835_5 Sporulation related domain - - - 0.0000000000000001314 90.0
HKD1_k127_197835_6 Protein of unknown function (DUF3106) - - - 0.00000000008431 72.0
HKD1_k127_197835_7 - - - - 0.00009259 53.0
HKD1_k127_2023223_0 Isocitrate dehydrogenase - - - 6.273e-223 698.0
HKD1_k127_2023223_1 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004721,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009987,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 559.0
HKD1_k127_2023223_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000007916 222.0
HKD1_k127_2023223_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000001583 107.0
HKD1_k127_2030833_0 Dehydratase family K01687 - 4.2.1.9 2.789e-250 784.0
HKD1_k127_2030833_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.78e-202 639.0
HKD1_k127_2030833_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 379.0
HKD1_k127_2030833_11 ATP phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 333.0
HKD1_k127_2030833_12 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 317.0
HKD1_k127_2030833_13 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001153 298.0
HKD1_k127_2030833_14 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005943 280.0
HKD1_k127_2030833_15 Belongs to the AB hydrolase superfamily. MetX family K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000002173 261.0
HKD1_k127_2030833_16 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K11755 GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000003101 240.0
HKD1_k127_2030833_17 Histidine biosynthesis protein K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000007861 233.0
HKD1_k127_2030833_18 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000001096 231.0
HKD1_k127_2030833_19 - - - - 0.00000000000000000000000000000000000000002162 161.0
HKD1_k127_2030833_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.332e-196 625.0
HKD1_k127_2030833_20 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000004063 119.0
HKD1_k127_2030833_21 protein, YerC YecD - - - 0.0000000000000000000000002727 108.0
HKD1_k127_2030833_3 cystathionine K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 511.0
HKD1_k127_2030833_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 473.0
HKD1_k127_2030833_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 468.0
HKD1_k127_2030833_6 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 457.0
HKD1_k127_2030833_7 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 449.0
HKD1_k127_2030833_8 Histidine biosynthesis bifunctional protein HisB K01089 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 433.0
HKD1_k127_2030833_9 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 374.0
HKD1_k127_2031451_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 352.0
HKD1_k127_2031451_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 352.0
HKD1_k127_2031451_2 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000003033 196.0
HKD1_k127_2031451_3 cytochrome - - - 0.000000000000000000000000000000000000000000002227 171.0
HKD1_k127_2031451_4 Protein of unknown function (DUF541) - - - 0.000000000000000000000000000000001311 139.0
HKD1_k127_2031451_5 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.000000000005696 70.0
HKD1_k127_2035999_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1474.0
HKD1_k127_2035999_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124 - - 6.14e-233 730.0
HKD1_k127_2035999_2 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.000000000000000000000000000000000000000000002604 166.0
HKD1_k127_2035999_3 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.000000000000104 76.0
HKD1_k127_2037223_0 Aminotransferase K01845 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 610.0
HKD1_k127_2037223_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 577.0
HKD1_k127_2037223_2 peptidase S16, lon K07157 - - 0.00000000000000000000000000000000000000000000000000000005363 203.0
HKD1_k127_2037223_3 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000004972 205.0
HKD1_k127_2037223_4 glycosyl - - - 0.0000000000000000000000000000000000000000000000000002159 198.0
HKD1_k127_2037223_5 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000004476 173.0
HKD1_k127_2037223_6 - - - - 0.00000000000000009465 89.0
HKD1_k127_2046985_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.547e-298 929.0
HKD1_k127_2046985_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.165e-251 785.0
HKD1_k127_2046985_10 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 391.0
HKD1_k127_2046985_11 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 361.0
HKD1_k127_2046985_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 293.0
HKD1_k127_2046985_13 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002316 271.0
HKD1_k127_2046985_14 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001219 257.0
HKD1_k127_2046985_15 Rnf-Nqr subunit, membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001794 231.0
HKD1_k127_2046985_16 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000002716 242.0
HKD1_k127_2046985_17 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000004001 233.0
HKD1_k127_2046985_18 Belongs to the MtfA family K09933 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000005505 230.0
HKD1_k127_2046985_19 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000005151 225.0
HKD1_k127_2046985_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.885e-247 774.0
HKD1_k127_2046985_20 Belongs to the DnaA family. HdA subfamily K10763 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000002851 201.0
HKD1_k127_2046985_21 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000001438 168.0
HKD1_k127_2046985_22 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000009045 164.0
HKD1_k127_2046985_24 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000001327 162.0
HKD1_k127_2046985_25 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000000000001878 148.0
HKD1_k127_2046985_26 PFAM acyl-coA-binding protein, ACBP - - - 0.00000000000000000000001331 103.0
HKD1_k127_2046985_27 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.00000000000000000000002322 106.0
HKD1_k127_2046985_28 protein conserved in bacteria K09938 - - 0.000000000000000000008926 104.0
HKD1_k127_2046985_3 Protein tyrosine kinase - - - 1.953e-231 743.0
HKD1_k127_2046985_30 Predicted membrane protein (DUF2069) - - - 0.000003951 54.0
HKD1_k127_2046985_4 PFAM Type II secretion system protein E - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 494.0
HKD1_k127_2046985_5 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 504.0
HKD1_k127_2046985_6 Major facilitator superfamily K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 485.0
HKD1_k127_2046985_7 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 476.0
HKD1_k127_2046985_8 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 464.0
HKD1_k127_2046985_9 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 443.0
HKD1_k127_2059653_0 Exodeoxyribonuclease IX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 305.0
HKD1_k127_2059653_1 Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001699 259.0
HKD1_k127_2059653_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000007172 147.0
HKD1_k127_2059653_3 HNH endonuclease - - - 0.00000001011 56.0
HKD1_k127_2060939_0 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 441.0
HKD1_k127_2060939_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 433.0
HKD1_k127_2060939_2 glutathione s-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 317.0
HKD1_k127_2060939_3 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.00000000000000000000000000000000000000000000000003051 182.0
HKD1_k127_2062567_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit - - - 1.037e-199 632.0
HKD1_k127_2062567_1 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 590.0
HKD1_k127_2062567_2 nucleoside-diphosphate sugar epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 569.0
HKD1_k127_2062567_3 cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 324.0
HKD1_k127_2062567_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002665 297.0
HKD1_k127_2062567_5 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009027 298.0
HKD1_k127_2062567_6 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000002086 212.0
HKD1_k127_2062567_7 ATP synthase subunit D K02120 - - 0.00000000000000000000000000009331 127.0
HKD1_k127_2062567_8 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.0000008417 56.0
HKD1_k127_2067460_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2563.0
HKD1_k127_2067460_1 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 479.0
HKD1_k127_2067460_10 Belongs to the Nudix hydrolase family K01515 - 3.6.1.13 0.000000000000007758 76.0
HKD1_k127_2067460_2 valine-pyruvate transaminase activity K00835 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009042,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0030632,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 432.0
HKD1_k127_2067460_3 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000005842 233.0
HKD1_k127_2067460_4 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000001493 248.0
HKD1_k127_2067460_5 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000033 196.0
HKD1_k127_2067460_6 Hydrolase K20862 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0022611,GO:0032502,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104 0.00000000000000000000000000000000000000000000000001605 188.0
HKD1_k127_2067460_7 - - - - 0.000000000000000000000000000000000000000000001102 173.0
HKD1_k127_2067460_8 - - - - 0.00000000000000000000000000000000001301 143.0
HKD1_k127_2067460_9 UPF0761 membrane protein K07058 - - 0.00000000000000001521 88.0
HKD1_k127_2068053_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 5.877e-279 869.0
HKD1_k127_2068053_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.683e-219 691.0
HKD1_k127_2068053_10 glyoxalase III activity - - - 0.00000000000000000000000000000000001506 145.0
HKD1_k127_2068053_11 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000000000001539 151.0
HKD1_k127_2068053_12 amino acid K03293,K16237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000001655 67.0
HKD1_k127_2068053_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 558.0
HKD1_k127_2068053_3 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 530.0
HKD1_k127_2068053_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 500.0
HKD1_k127_2068053_5 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 444.0
HKD1_k127_2068053_6 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000002423 222.0
HKD1_k127_2068053_7 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000002135 189.0
HKD1_k127_2068053_8 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000000003412 158.0
HKD1_k127_2068053_9 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - - 0.000000000000000000000000000000000002862 146.0
HKD1_k127_2073031_0 Major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 520.0
HKD1_k127_2073031_1 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 426.0
HKD1_k127_2073031_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008846 286.0
HKD1_k127_2073031_3 UPF0056 membrane protein K05595 - - 0.00000000000000000000000000000000000000000000008626 176.0
HKD1_k127_2073031_4 Rieske [2Fe-2S] domain - - - 0.00000000000000000000004658 115.0
HKD1_k127_2073031_5 - - - - 0.0000000000000000003095 93.0
HKD1_k127_2073031_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 0.0000000000000000005112 87.0
HKD1_k127_2073031_7 Short repeat of unknown function (DUF308) - - - 0.00000001066 61.0
HKD1_k127_2076640_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01668 - 4.1.99.2 4.669e-260 811.0
HKD1_k127_2076640_1 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000009166 184.0
HKD1_k127_2076640_2 - - - - 0.00008055 46.0
HKD1_k127_2078572_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 6.023e-216 696.0
HKD1_k127_2078572_1 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 455.0
HKD1_k127_2078572_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000005797 226.0
HKD1_k127_2078572_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000000000000000000000000000000000001614 224.0
HKD1_k127_2078572_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000001443 158.0
HKD1_k127_2078572_6 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000001604 108.0
HKD1_k127_2078572_7 Polysaccharide biosynthesis protein - - - 0.000000000000007691 88.0
HKD1_k127_2081773_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.185e-195 632.0
HKD1_k127_2081773_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 518.0
HKD1_k127_2081773_10 TolA C-terminal K03646 - - 0.000000000001275 78.0
HKD1_k127_2081773_2 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 447.0
HKD1_k127_2081773_3 E3 component of 2-oxoglutarate dehydrogenase complex K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003663 268.0
HKD1_k127_2081773_4 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002875 256.0
HKD1_k127_2081773_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000003113 231.0
HKD1_k127_2081773_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000002169 183.0
HKD1_k127_2081773_7 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000004344 153.0
HKD1_k127_2081773_8 Biopolymer transport protein K03560 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000005544 149.0
HKD1_k127_2081773_9 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000002611 151.0
HKD1_k127_2088613_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 8.908e-236 742.0
HKD1_k127_2088613_1 SBF-like CPA transporter family (DUF4137) K03453 - - 0.00000000000035 82.0
HKD1_k127_210035_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.248e-307 949.0
HKD1_k127_210035_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 7.875e-265 838.0
HKD1_k127_210035_10 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000008161 248.0
HKD1_k127_210035_11 - - - - 0.0000000000000000000000000000000000000000000000000000000007885 213.0
HKD1_k127_210035_12 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000001915 213.0
HKD1_k127_210035_13 Competence protein - - - 0.000000000000000000000000000000000000000000000000000008974 197.0
HKD1_k127_210035_14 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000004228 190.0
HKD1_k127_210035_15 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000001699 190.0
HKD1_k127_210035_16 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.0000000000000000000000000000000000003584 145.0
HKD1_k127_210035_17 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.000000000000000000005363 100.0
HKD1_k127_210035_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 2.232e-242 763.0
HKD1_k127_210035_3 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 537.0
HKD1_k127_210035_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 459.0
HKD1_k127_210035_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 439.0
HKD1_k127_210035_6 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 435.0
HKD1_k127_210035_7 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 365.0
HKD1_k127_210035_8 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 332.0
HKD1_k127_210035_9 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 314.0
HKD1_k127_2109065_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1240.0
HKD1_k127_2109065_1 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 4.007e-321 992.0
HKD1_k127_2109065_10 PFAM Pyruvate carboxyltransferase K01640,K18314 - 4.1.3.4,4.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 397.0
HKD1_k127_2109065_11 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 357.0
HKD1_k127_2109065_12 hydrolase activity, acting on ester bonds K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 305.0
HKD1_k127_2109065_13 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 293.0
HKD1_k127_2109065_14 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001338 284.0
HKD1_k127_2109065_15 isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000004387 229.0
HKD1_k127_2109065_16 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000003267 204.0
HKD1_k127_2109065_17 - - - - 0.000000000000000000000000000000000000000000000000000001212 199.0
HKD1_k127_2109065_18 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000001007 190.0
HKD1_k127_2109065_19 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000001396 187.0
HKD1_k127_2109065_2 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 5.118e-281 880.0
HKD1_k127_2109065_20 Isochorismatase family K13995 - 3.5.1.107 0.000000000000000000000000000000000000000000001985 172.0
HKD1_k127_2109065_21 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000001255 132.0
HKD1_k127_2109065_22 - - - - 0.0000000000000000000000000000008088 135.0
HKD1_k127_2109065_23 protein acetylation - - - 0.00000000000000000000004579 105.0
HKD1_k127_2109065_3 ATP-dependent helicase K03578 - 3.6.4.13 5.781e-257 813.0
HKD1_k127_2109065_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 591.0
HKD1_k127_2109065_5 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 563.0
HKD1_k127_2109065_6 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 552.0
HKD1_k127_2109065_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 443.0
HKD1_k127_2109065_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 438.0
HKD1_k127_2109065_9 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 406.0
HKD1_k127_2114889_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006599 504.0
HKD1_k127_2114889_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 334.0
HKD1_k127_2114889_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000001469 156.0
HKD1_k127_2114889_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000002726 154.0
HKD1_k127_2114889_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000002253 143.0
HKD1_k127_2115377_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 389.0
HKD1_k127_2115377_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.00000000000000000000000002389 114.0
HKD1_k127_2115377_3 Histidine kinase - - - 0.0000000000000000000000009379 105.0
HKD1_k127_2117489_0 acyl-CoA dehydrogenase - - - 6.607e-226 714.0
HKD1_k127_2117489_1 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 593.0
HKD1_k127_2117489_10 protein involved in response to NO K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001193 263.0
HKD1_k127_2117489_11 COG1024 Enoyl-CoA hydratase carnithine racemase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000003629 223.0
HKD1_k127_2117489_12 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000001198 186.0
HKD1_k127_2117489_13 PFAM Cyclic nucleotide-binding K21563 - - 0.0000000000000000000000000000000000000000004418 166.0
HKD1_k127_2117489_14 Cupin superfamily (DUF985) K09705 - - 0.00000000000000000000000000000000002621 146.0
HKD1_k127_2117489_15 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000001118 133.0
HKD1_k127_2117489_16 Invasion gene expression up-regulator, SirB - - - 0.0000000000000000000000000000005459 128.0
HKD1_k127_2117489_17 Acyl-CoA synthetase (NDP forming) K09181 - - 0.00000000000000000000000000001059 125.0
HKD1_k127_2117489_18 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000788 122.0
HKD1_k127_2117489_19 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.0000000000000000000000004934 117.0
HKD1_k127_2117489_2 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 598.0
HKD1_k127_2117489_20 CHAD - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000002973 86.0
HKD1_k127_2117489_21 - - - - 0.00000000028 65.0
HKD1_k127_2117489_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 563.0
HKD1_k127_2117489_4 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 500.0
HKD1_k127_2117489_5 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 462.0
HKD1_k127_2117489_6 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 448.0
HKD1_k127_2117489_7 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 423.0
HKD1_k127_2117489_8 Acyl-CoA thioesterase K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 312.0
HKD1_k127_2117489_9 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 298.0
HKD1_k127_2129572_0 Glycine cleavage T-protein C-terminal barrel domain K00302,K22086 - 1.5.3.1,1.5.99.5 0.0 1328.0
HKD1_k127_2129572_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 9.505e-234 742.0
HKD1_k127_2129572_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 513.0
HKD1_k127_2129572_3 FAD dependent oxidoreductase K22084 - 1.5.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 389.0
HKD1_k127_2129572_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 295.0
HKD1_k127_2129572_5 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000007495 236.0
HKD1_k127_2129572_6 Sarcosine oxidase, gamma subunit K00305,K22087 - 1.5.3.1,1.5.99.5 0.000000000000000000000000000000000001249 151.0
HKD1_k127_2129572_7 Sarcosine oxidase, delta subunit family K00304,K22085 - 1.5.3.1,1.5.99.5 0.000000000000000000000000000000000001381 139.0
HKD1_k127_2137022_0 AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 552.0
HKD1_k127_2137022_1 Putative 2OG-Fe(II) oxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 308.0
HKD1_k127_2137022_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009947 264.0
HKD1_k127_2137022_3 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000006716 161.0
HKD1_k127_2137022_4 - - - - 0.0000000005064 64.0
HKD1_k127_2137022_5 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX - - - 0.00000008882 61.0
HKD1_k127_2139016_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 452.0
HKD1_k127_2139016_1 Possible lysine decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 284.0
HKD1_k127_2139691_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 401.0
HKD1_k127_2139691_1 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006664 290.0
HKD1_k127_2139691_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000646 285.0
HKD1_k127_2139691_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001255 274.0
HKD1_k127_2139691_4 protein conserved in bacteria K09800 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347 - 0.0000000000000000000000000000000000000000000000000000000000000000000000005534 263.0
HKD1_k127_2139691_5 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000002406 232.0
HKD1_k127_2139691_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000002128 199.0
HKD1_k127_2139691_7 Belongs to the ATCase OTCase family K09065,K13043 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 0.00000000000000000000000000000000000001784 151.0
HKD1_k127_2139691_8 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000002997 105.0
HKD1_k127_2154930_0 glucuronate isomerase K01812 - 5.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 566.0
HKD1_k127_2154930_1 mevalonate kinase activity K00869,K00938,K16190 - 2.7.1.36,2.7.1.43,2.7.4.2 0.000003396 49.0
HKD1_k127_2160448_0 Pfam Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 605.0
HKD1_k127_2160448_1 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003357 235.0
HKD1_k127_2160448_2 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000000000000000000000000001143 204.0
HKD1_k127_2160448_3 Rhodanese Homology Domain - - - 0.0000000001552 75.0
HKD1_k127_2163028_0 Sulfatase - - - 1.058e-262 820.0
HKD1_k127_2163028_1 glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 331.0
HKD1_k127_2163028_3 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000008693 196.0
HKD1_k127_2163028_4 Kelch motif - - - 0.0000000000000000000000000000000000000001573 159.0
HKD1_k127_218070_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1244.0
HKD1_k127_218070_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 376.0
HKD1_k127_218070_2 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001581 264.0
HKD1_k127_218070_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000242 263.0
HKD1_k127_218070_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000003898 212.0
HKD1_k127_2209398_0 FAD dependent oxidoreductase K07077 - - 7.485e-216 692.0
HKD1_k127_2209398_1 Thioesterase K07107 - - 0.0000000000000000000000000003534 123.0
HKD1_k127_2223287_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 546.0
HKD1_k127_2223287_1 Response regulator of the LytR AlgR family K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001799 261.0
HKD1_k127_2223287_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000005742 216.0
HKD1_k127_2223287_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000002591 191.0
HKD1_k127_2223287_4 carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000008355 133.0
HKD1_k127_2223287_5 Cupin 2, conserved barrel domain protein K21700 - - 0.000000000000000000000003116 107.0
HKD1_k127_2223287_6 transcriptional regulator K16138 - - 0.00000000000004822 76.0
HKD1_k127_2223287_7 Histidine kinase - - - 0.000000004306 68.0
HKD1_k127_2229165_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 493.0
HKD1_k127_2229165_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 444.0
HKD1_k127_2229165_2 Sugar (and other) transporter K08195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007173 442.0
HKD1_k127_2229165_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000143 251.0
HKD1_k127_2229165_4 myo-inosose-2 dehydratase activity - - - 0.000000000000000005371 88.0
HKD1_k127_2243448_0 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 511.0
HKD1_k127_2243448_1 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 362.0
HKD1_k127_2243448_2 META domain - - - 0.00000000000000000000000000006268 117.0
HKD1_k127_2244458_0 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 6.94e-237 750.0
HKD1_k127_2244458_1 protein conserved in bacteria - - - 7.753e-209 666.0
HKD1_k127_2244458_10 - - - - 0.0000003382 61.0
HKD1_k127_2244458_11 Cytochrome b/b6/petB K12262 - - 0.0005539 47.0
HKD1_k127_2244458_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 443.0
HKD1_k127_2244458_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 439.0
HKD1_k127_2244458_4 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 324.0
HKD1_k127_2244458_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000001007 247.0
HKD1_k127_2244458_6 Sugar (and other) transporter K07552 - - 0.0000000000000000000000000000000000000000000000000003614 203.0
HKD1_k127_2244458_7 YceI-like domain - - - 0.000000000000000000000000000002961 129.0
HKD1_k127_2244458_8 Protein of unknown function (DUF2845) - - - 0.00000000001101 72.0
HKD1_k127_2244458_9 Protein of unknown function (DUF2845) - - - 0.00000000005752 71.0
HKD1_k127_2250079_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 335.0
HKD1_k127_2250079_1 protein conserved in bacteria K03690 - - 0.000000000000000000000002283 111.0
HKD1_k127_2250079_2 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000004102 76.0
HKD1_k127_2257667_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 4.559e-218 687.0
HKD1_k127_2257667_1 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 2.49e-217 683.0
HKD1_k127_2257667_10 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000244 229.0
HKD1_k127_2257667_11 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000000003554 178.0
HKD1_k127_2257667_12 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000002126 129.0
HKD1_k127_2257667_13 transcriptional regulator K06995 - - 0.00000000000000000000000000003312 121.0
HKD1_k127_2257667_2 Belongs to the aldehyde dehydrogenase family K00130,K09472,K12254 - 1.2.1.54,1.2.1.8,1.2.1.99 5.664e-213 672.0
HKD1_k127_2257667_3 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 514.0
HKD1_k127_2257667_4 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 480.0
HKD1_k127_2257667_5 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 453.0
HKD1_k127_2257667_6 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 439.0
HKD1_k127_2257667_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 328.0
HKD1_k127_2257667_8 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002837 240.0
HKD1_k127_2257667_9 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000003475 239.0
HKD1_k127_2266906_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 514.0
HKD1_k127_2266906_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 429.0
HKD1_k127_2266906_2 ABC transporter, ATP-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 355.0
HKD1_k127_2266906_3 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 319.0
HKD1_k127_2266906_4 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 312.0
HKD1_k127_2266906_5 modulation protein K05808 - - 0.000000000000000000000000000001327 126.0
HKD1_k127_2266906_6 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.000000001039 66.0
HKD1_k127_2309908_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 326.0
HKD1_k127_2309908_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000002615 82.0
HKD1_k127_2318641_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 2.269e-267 834.0
HKD1_k127_2318641_1 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 407.0
HKD1_k127_2318641_2 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 391.0
HKD1_k127_2318641_3 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 361.0
HKD1_k127_2318641_4 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004009 276.0
HKD1_k127_2318641_5 Belongs to the peptidase S51 family - - - 0.0000000000000000000000000000000000000000000000008087 194.0
HKD1_k127_2318641_6 Domain of unknown function (DUF1840) - - - 0.00000000000003965 76.0
HKD1_k127_2318641_7 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.0000009108 60.0
HKD1_k127_232163_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1436.0
HKD1_k127_232163_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 4.489e-280 871.0
HKD1_k127_232163_2 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 594.0
HKD1_k127_232163_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925,K19697 - 2.7.2.1,2.7.2.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 372.0
HKD1_k127_232163_4 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000002986 179.0
HKD1_k127_232163_5 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000000001044 94.0
HKD1_k127_232163_6 PFAM OsmC-like protein - - - 0.0002234 50.0
HKD1_k127_2323046_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 380.0
HKD1_k127_2323046_1 ErfK YbiS YcfS YnhG K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 298.0
HKD1_k127_2323046_2 Maf-like protein K06287 GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0047429 - 0.000000000000000000000000000000000000000000000000007724 197.0
HKD1_k127_2323046_3 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000211 156.0
HKD1_k127_2323046_4 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000006425 109.0
HKD1_k127_2323046_5 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000004767 91.0
HKD1_k127_2323046_6 Uncharacterized ACR, COG1399 - - - 0.000000000001142 75.0
HKD1_k127_2327087_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 394.0
HKD1_k127_2327087_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 287.0
HKD1_k127_2327087_2 Forms part of the polypeptide exit tunnel K02926 GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000008556 244.0
HKD1_k127_2327087_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000008092 178.0
HKD1_k127_2327087_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000004229 109.0
HKD1_k127_2327087_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000002212 81.0
HKD1_k127_233414_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 5.68e-209 653.0
HKD1_k127_233414_1 ATP-dependent helicase K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 536.0
HKD1_k127_233414_10 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 340.0
HKD1_k127_233414_11 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 327.0
HKD1_k127_233414_12 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 295.0
HKD1_k127_233414_13 Acetyltransferases including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000007361 177.0
HKD1_k127_233414_14 Bacterial type II and III secretion system protein - - - 0.00000000000000000000000000000000000005461 155.0
HKD1_k127_233414_15 - - - - 0.000000000000000000000000000000008756 134.0
HKD1_k127_233414_16 NlpC/P60 family - - - 0.000000000000000000000000000239 125.0
HKD1_k127_233414_17 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000002119 91.0
HKD1_k127_233414_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 461.0
HKD1_k127_233414_3 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 448.0
HKD1_k127_233414_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 422.0
HKD1_k127_233414_5 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 408.0
HKD1_k127_233414_6 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 387.0
HKD1_k127_233414_7 Cardiolipin synthase K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 389.0
HKD1_k127_233414_8 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 370.0
HKD1_k127_233414_9 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 365.0
HKD1_k127_2335418_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 2.173e-207 655.0
HKD1_k127_2335418_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.633e-195 617.0
HKD1_k127_2335418_10 carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 324.0
HKD1_k127_2335418_11 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 301.0
HKD1_k127_2335418_12 Transcriptional regulator sugar kinase K00845,K00886 - 2.7.1.2,2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000004418 242.0
HKD1_k127_2335418_13 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000008972 213.0
HKD1_k127_2335418_14 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01761 - 4.4.1.11 0.00000000000000000000000000006779 122.0
HKD1_k127_2335418_15 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000003707 100.0
HKD1_k127_2335418_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072,K11076 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 543.0
HKD1_k127_2335418_3 oxidoreductase K09471 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 512.0
HKD1_k127_2335418_4 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 509.0
HKD1_k127_2335418_5 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 494.0
HKD1_k127_2335418_6 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 470.0
HKD1_k127_2335418_7 Aminotransferase class-V K14287 - 2.6.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 488.0
HKD1_k127_2335418_8 Binding-protein-dependent transport system inner membrane component K11071,K11075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 423.0
HKD1_k127_2335418_9 COG1177 ABC-type spermidine putrescine transport system, permease component II K11074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 389.0
HKD1_k127_234776_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 507.0
HKD1_k127_234776_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 450.0
HKD1_k127_234776_10 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000003846 153.0
HKD1_k127_234776_11 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000006213 138.0
HKD1_k127_234776_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000383 99.0
HKD1_k127_234776_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000001219 72.0
HKD1_k127_234776_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 441.0
HKD1_k127_234776_3 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000002713 262.0
HKD1_k127_234776_4 EamA-like transporter family K15268 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006866 256.0
HKD1_k127_234776_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001595 248.0
HKD1_k127_234776_6 HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000707 244.0
HKD1_k127_234776_7 Biopolymer transporter ExbB K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000001234 248.0
HKD1_k127_234776_8 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000002494 233.0
HKD1_k127_234776_9 Aminotransferase K03430 - 2.6.1.37 0.0000000000000000000000000000000000000000000000000000001897 214.0
HKD1_k127_2350012_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 513.0
HKD1_k127_2350012_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 490.0
HKD1_k127_2350012_2 N-acetylmuramoyl-L-alanine amidase K01448 GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 341.0
HKD1_k127_2350012_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 333.0
HKD1_k127_2350012_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 308.0
HKD1_k127_2350012_5 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000161 258.0
HKD1_k127_2350012_6 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.000000000000000000000000000000000000007143 156.0
HKD1_k127_2350012_7 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000002495 139.0
HKD1_k127_2350012_8 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000001553 136.0
HKD1_k127_2378983_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 323.0
HKD1_k127_2378983_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000001773 211.0
HKD1_k127_2427734_0 Histidine kinase K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004749 288.0
HKD1_k127_2427734_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K02667 - - 0.0000000000000000000000000000000000000000000000000000001175 201.0
HKD1_k127_2427734_2 GtrA-like protein - - - 0.00000000000008178 82.0
HKD1_k127_242919_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 6.851e-206 649.0
HKD1_k127_242919_1 Serine aminopeptidase, S33 K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 404.0
HKD1_k127_242919_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000002068 152.0
HKD1_k127_2440923_0 Belongs to the GcvT family K00315 - 1.5.8.4 0.0 1263.0
HKD1_k127_2440923_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 1.857e-223 700.0
HKD1_k127_2440923_2 Sarcosine oxidase beta subunit K00303,K22084 - 1.5.3.1,1.5.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 382.0
HKD1_k127_2463155_0 Sulfate transporter antisigma-factor antagonist STAS - - - 4.19e-247 770.0
HKD1_k127_2467681_0 Tetratricopeptide repeat K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 611.0
HKD1_k127_2467681_1 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000005495 245.0
HKD1_k127_2476892_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 4.813e-234 745.0
HKD1_k127_2476892_1 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 4.693e-231 733.0
HKD1_k127_2476892_2 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00632 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.16 2.437e-198 623.0
HKD1_k127_2476892_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 574.0
HKD1_k127_2476892_4 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 481.0
HKD1_k127_2476892_5 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K01782,K01825 GO:0003674,GO:0003824,GO:0003857,GO:0004165,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 351.0
HKD1_k127_2476892_6 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 351.0
HKD1_k127_2476892_7 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 341.0
HKD1_k127_2476892_8 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.000000000000000000000000000000000000000000000000000000005497 222.0
HKD1_k127_2476892_9 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000001967 177.0
HKD1_k127_2482407_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1283.0
HKD1_k127_2482407_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 529.0
HKD1_k127_2482407_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 475.0
HKD1_k127_2482407_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 391.0
HKD1_k127_2482407_4 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 388.0
HKD1_k127_2482407_5 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 337.0
HKD1_k127_2482407_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000009087 184.0
HKD1_k127_2482407_7 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000003575 151.0
HKD1_k127_2482407_8 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000000000000000009364 132.0
HKD1_k127_2482407_9 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000539 104.0
HKD1_k127_249594_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1088.0
HKD1_k127_2537120_0 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 462.0
HKD1_k127_2537120_1 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 320.0
HKD1_k127_2537120_2 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000002438 230.0
HKD1_k127_2537120_3 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000000000000007624 211.0
HKD1_k127_2537120_4 Membrane fusogenic activity K09806 - - 0.000000000000000001569 91.0
HKD1_k127_254546_0 CoA-binding domain protein K09181 - - 2.724e-261 833.0
HKD1_k127_254546_1 Flavin-binding monooxygenase-like - - - 2.144e-232 734.0
HKD1_k127_254546_2 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 470.0
HKD1_k127_254546_3 histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 374.0
HKD1_k127_254546_4 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000845 278.0
HKD1_k127_254546_5 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244,K19743 - 1.4.1.1,1.5.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000003522 272.0
HKD1_k127_254546_6 COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0000000000000000000000000000000001436 136.0
HKD1_k127_255263_0 membrane protein, TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 394.0
HKD1_k127_255263_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 394.0
HKD1_k127_255263_10 - - - - 0.000000003289 63.0
HKD1_k127_255263_11 ATP synthase (F/14-kDa) subunit - - - 0.00008661 49.0
HKD1_k127_255263_12 - - - - 0.0003269 51.0
HKD1_k127_255263_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 403.0
HKD1_k127_255263_3 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 381.0
HKD1_k127_255263_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 345.0
HKD1_k127_255263_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000005906 140.0
HKD1_k127_255263_6 - - - - 0.0000000000000000000000000000000000006058 149.0
HKD1_k127_255263_7 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.000000000000000000000002601 116.0
HKD1_k127_255263_8 PilZ domain - - - 0.0000000000252 67.0
HKD1_k127_2608114_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.0000000000000000000000000000000000002654 145.0
HKD1_k127_2608114_1 pfam nudix - - - 0.00000000000000000000000008431 116.0
HKD1_k127_2609638_0 Belongs to the aldehyde dehydrogenase family K00135,K22445 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 436.0
HKD1_k127_2609638_1 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 334.0
HKD1_k127_2609638_2 Pkd domain containing protein - - - 0.000000000000000000000000244 124.0
HKD1_k127_2609638_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000001409 64.0
HKD1_k127_2609638_4 Papain family cysteine protease - - - 0.0000003226 64.0
HKD1_k127_265186_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 9.879e-228 712.0
HKD1_k127_265186_1 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 314.0
HKD1_k127_265186_2 Ribosomal protein L11 methyltransferase K02687 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 302.0
HKD1_k127_265186_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000116 204.0
HKD1_k127_265186_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000002082 168.0
HKD1_k127_265186_5 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000003789 126.0
HKD1_k127_265186_6 Protein of unknown function (DUF3426) - - - 0.00000003429 63.0
HKD1_k127_2661799_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1182.0
HKD1_k127_2661799_1 salt-induced outer membrane protein K07283 - - 0.0000000000000000000000000000000000000000000000004673 183.0
HKD1_k127_2661799_2 PFAM Thioredoxin K05838 - - 0.0000000000000000000000000000000000000383 147.0
HKD1_k127_2681813_0 Hypothetical glycosyl hydrolase family 13 K11931 - - 9.766e-278 870.0
HKD1_k127_2681813_1 AMP-binding enzyme C-terminal domain K00666 - - 8.072e-259 805.0
HKD1_k127_2681813_10 Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000006773 123.0
HKD1_k127_2681813_11 PgaD-like protein - - - 0.000000000000000000000000001465 117.0
HKD1_k127_2681813_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000007358 74.0
HKD1_k127_2681813_13 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000009393 79.0
HKD1_k127_2681813_2 Glycosyl transferase family 21 K11936 - - 1.071e-207 653.0
HKD1_k127_2681813_3 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 567.0
HKD1_k127_2681813_4 Protoporphyrinogen oxidase K00230 GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000006586 243.0
HKD1_k127_2681813_5 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000259 241.0
HKD1_k127_2681813_6 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000006245 213.0
HKD1_k127_2681813_7 Water Stress and Hypersensitive response - - - 0.00000000000000000000000000000000000000000001603 168.0
HKD1_k127_2681813_8 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000008074 160.0
HKD1_k127_2681813_9 - - - - 0.000000000000000000000000000000000000000004341 162.0
HKD1_k127_271809_0 Fatty acid desaturase K00496 - 1.14.15.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 357.0
HKD1_k127_271809_1 Steryl acetyl hydrolase K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000000000000000000000002832 241.0
HKD1_k127_271809_2 Alkylated DNA repair protein - - - 0.00000000000000000000000000000000000000000000000000000001196 208.0
HKD1_k127_271809_3 Transcriptional regulator - - - 0.00000000000000000000000000000000288 149.0
HKD1_k127_271809_4 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000001182 110.0
HKD1_k127_271809_5 Esterase lipase K14731 - 3.1.1.83 0.0000000008232 61.0
HKD1_k127_273980_0 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 291.0
HKD1_k127_273980_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001085 269.0
HKD1_k127_273980_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000102 255.0
HKD1_k127_273980_3 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001375 257.0
HKD1_k127_273980_4 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000000007065 189.0
HKD1_k127_273980_5 Belongs to the bacterial histone-like protein family - - - 0.000000000000000000000000000007594 121.0
HKD1_k127_273980_6 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000005145 123.0
HKD1_k127_273980_7 Domain of unknown function (DUF4426) - - - 0.00000000000000000001928 98.0
HKD1_k127_273980_8 Belongs to the UPF0235 family K09131 - - 0.00000000000000000002643 96.0
HKD1_k127_2788978_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 565.0
HKD1_k127_2788978_1 Amino acid permease K11735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 437.0
HKD1_k127_2788978_2 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 415.0
HKD1_k127_2788978_3 Belongs to the long-chain O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000334 299.0
HKD1_k127_2788978_4 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002117 280.0
HKD1_k127_2788978_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003823 269.0
HKD1_k127_2788978_6 enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000002467 249.0
HKD1_k127_2788978_7 META domain - - - 0.0000000000000000000000000000000000004443 154.0
HKD1_k127_2793757_0 Two component response regulator for the phosphate regulon K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 310.0
HKD1_k127_2793757_1 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000003016 164.0
HKD1_k127_2813489_0 Putative inner membrane exporter, YdcZ - - - 0.00000000000000000000000004191 115.0
HKD1_k127_2813489_1 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000001271 102.0
HKD1_k127_2813489_2 Protein of unknown function (DUF3024) - - - 0.000000000000183 77.0
HKD1_k127_2813489_3 Thiol-disulfide isomerase and thioredoxins - - - 0.00000987 48.0
HKD1_k127_282908_0 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000005305 194.0
HKD1_k127_282908_1 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000001036 134.0
HKD1_k127_282908_2 - - - - 0.000000000000000000000001497 115.0
HKD1_k127_2841630_0 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 404.0
HKD1_k127_2841630_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003718 278.0
HKD1_k127_2841630_2 Protein of unknown function (DUF3302) - - - 0.000000000000000000000000000000000002013 149.0
HKD1_k127_2841630_3 AI-2E family transporter - - - 0.0000000000000000000000000000000004524 132.0
HKD1_k127_2917099_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 516.0
HKD1_k127_2917099_1 PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000003708 131.0
HKD1_k127_2942354_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1091.0
HKD1_k127_2942354_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 4.287e-311 967.0
HKD1_k127_2942354_10 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000474 151.0
HKD1_k127_2942354_11 TIGRFAM Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000005959 140.0
HKD1_k127_2942354_12 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000002564 131.0
HKD1_k127_2942354_13 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000002836 106.0
HKD1_k127_2942354_14 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.0000000000000000000002055 108.0
HKD1_k127_2942354_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 5.244e-291 916.0
HKD1_k127_2942354_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 8.861e-232 732.0
HKD1_k127_2942354_4 Participates in both transcription termination and antitermination K02600 - - 5.262e-222 698.0
HKD1_k127_2942354_5 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 600.0
HKD1_k127_2942354_6 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 291.0
HKD1_k127_2942354_7 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008746 314.0
HKD1_k127_2942354_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000002936 255.0
HKD1_k127_2942354_9 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.0000000000000000000000000000000000000000000000008417 183.0
HKD1_k127_294985_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009529 278.0
HKD1_k127_294985_1 MafB19-like deaminase K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002039 255.0
HKD1_k127_294985_2 XdhC Rossmann domain - - - 0.0000000000000000000000000000000000000000000000000000000000007842 214.0
HKD1_k127_294985_3 Cache domain - - - 0.00000000000000000000000000000000000000000000001136 186.0
HKD1_k127_294985_4 - - - - 0.000000000000000000000000000000000000000453 166.0
HKD1_k127_294985_5 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000000001824 124.0
HKD1_k127_294985_6 Cupin 2, conserved barrel domain protein K21700 - - 0.000000414 58.0
HKD1_k127_294985_7 TIR domain - - - 0.0003533 51.0
HKD1_k127_3027678_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 596.0
HKD1_k127_3027678_1 DNA mediated transformation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 439.0
HKD1_k127_3027678_2 Carboxypeptidase K13049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 323.0
HKD1_k127_3033099_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.269e-306 949.0
HKD1_k127_3033099_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 529.0
HKD1_k127_3033099_10 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000002731 111.0
HKD1_k127_3033099_11 CRS1_YhbY K07574 - - 0.000000000000000000000002627 108.0
HKD1_k127_3033099_12 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000007456 93.0
HKD1_k127_3033099_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009101 356.0
HKD1_k127_3033099_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009189 307.0
HKD1_k127_3033099_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 310.0
HKD1_k127_3033099_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 317.0
HKD1_k127_3033099_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000008049 265.0
HKD1_k127_3033099_7 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000001606 249.0
HKD1_k127_3033099_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000006766 205.0
HKD1_k127_3033099_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000004123 172.0
HKD1_k127_3037649_0 Dak2 K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 493.0
HKD1_k127_3037649_1 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 466.0
HKD1_k127_3037649_2 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 332.0
HKD1_k127_3037649_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001798 272.0
HKD1_k127_3037649_4 Type II secretion system protein B K02451 - - 0.000000000001253 78.0
HKD1_k127_3043828_0 Belongs to the CarB family K01955 - 6.3.5.5 1.487e-229 721.0
HKD1_k127_3043828_1 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 547.0
HKD1_k127_3051894_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 473.0
HKD1_k127_3051894_1 Splits dipeptides with a prolyl residue in the C- terminal position K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 453.0
HKD1_k127_3051894_2 Ribosomal protein L17 K02879 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000002721 164.0
HKD1_k127_3051894_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000007526 153.0
HKD1_k127_3051919_0 Peptidase family M49 - - - 5.347e-219 692.0
HKD1_k127_3051919_1 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 542.0
HKD1_k127_3051919_10 PFAM ADP-ribosylation Crystallin J1 K05521 - 3.2.2.24 0.00000000000000000000000000004642 134.0
HKD1_k127_3051919_11 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000316 121.0
HKD1_k127_3051919_12 - - - - 0.0000000000000000000001052 101.0
HKD1_k127_3051919_13 Bacterial virulence protein (VirJ) - - - 0.0000000000000000002882 89.0
HKD1_k127_3051919_14 Protein of unknown function (DUF2934) - - - 0.00000003029 60.0
HKD1_k127_3051919_2 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 462.0
HKD1_k127_3051919_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 418.0
HKD1_k127_3051919_4 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 400.0
HKD1_k127_3051919_5 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 328.0
HKD1_k127_3051919_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 322.0
HKD1_k127_3051919_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000002002 257.0
HKD1_k127_3051919_8 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000002033 224.0
HKD1_k127_3051919_9 Dual specificity phosphatase, catalytic domain - - - 0.00000000000000000000000000001958 135.0
HKD1_k127_3055139_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 5.364e-284 882.0
HKD1_k127_3055139_1 Biotin-lipoyl like K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 475.0
HKD1_k127_3055139_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 299.0
HKD1_k127_3055139_3 PFAM GGDEF domain containing protein - - - 0.00000000000004158 74.0
HKD1_k127_3060699_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1619.0
HKD1_k127_3060699_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.398e-264 830.0
HKD1_k127_3060699_10 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 392.0
HKD1_k127_3060699_11 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 291.0
HKD1_k127_3060699_12 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004073 274.0
HKD1_k127_3060699_13 Lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007404 293.0
HKD1_k127_3060699_14 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000001346 268.0
HKD1_k127_3060699_15 Involved in formation and maintenance of cell shape K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0043621,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944,GO:0071963 - 0.000000000000000000000000000000000000000000000000000000000000000000000591 249.0
HKD1_k127_3060699_16 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000001227 182.0
HKD1_k127_3060699_17 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.0000000000000000000000000000000000000000000002404 171.0
HKD1_k127_3060699_18 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.0000000000000000000000000000001841 130.0
HKD1_k127_3060699_19 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000002377 111.0
HKD1_k127_3060699_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.164e-248 773.0
HKD1_k127_3060699_20 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000308 104.0
HKD1_k127_3060699_3 Peptidase m28 K01269 - - 2.905e-238 747.0
HKD1_k127_3060699_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.399e-215 683.0
HKD1_k127_3060699_5 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 8.54e-203 651.0
HKD1_k127_3060699_6 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 577.0
HKD1_k127_3060699_7 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 494.0
HKD1_k127_3060699_8 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 451.0
HKD1_k127_3060699_9 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 412.0
HKD1_k127_3061724_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 609.0
HKD1_k127_3061724_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 602.0
HKD1_k127_3061724_10 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 344.0
HKD1_k127_3061724_11 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000002613 203.0
HKD1_k127_3061724_12 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000004504 153.0
HKD1_k127_3061724_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000009045 95.0
HKD1_k127_3061724_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 514.0
HKD1_k127_3061724_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 460.0
HKD1_k127_3061724_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 464.0
HKD1_k127_3061724_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 421.0
HKD1_k127_3061724_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 401.0
HKD1_k127_3061724_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 419.0
HKD1_k127_3061724_8 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 388.0
HKD1_k127_3061724_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 387.0
HKD1_k127_3067310_0 abc transporter atp-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 344.0
HKD1_k127_3067310_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 350.0
HKD1_k127_3067310_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000001072 108.0
HKD1_k127_3067310_3 Putative neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.000000457 55.0
HKD1_k127_3070357_0 Histidine kinase - - - 0.0 1037.0
HKD1_k127_3070357_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 411.0
HKD1_k127_3070357_2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003939 255.0
HKD1_k127_3070357_4 Long-chain fatty aldehyde decarbonylase - - - 0.0000007625 51.0
HKD1_k127_3071150_0 Type II secretory pathway, component HofQ K02666 - - 1.333e-201 651.0
HKD1_k127_3071150_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 444.0
HKD1_k127_3071150_2 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000001022 215.0
HKD1_k127_3071150_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000000000000000005165 198.0
HKD1_k127_3071150_4 COG3166 Tfp pilus assembly protein PilN K02663 - - 0.0000000000000000000000000000000000000000000006277 172.0
HKD1_k127_3071150_5 pilus assembly protein pilp K02665 - - 0.0000000000000000000000000000000000000001441 164.0
HKD1_k127_3071150_6 COG4972 Tfp pilus assembly protein, ATPase PilM K02662 - - 0.000000000003215 68.0
HKD1_k127_308141_0 Peptidase M16 - - - 0.0 1064.0
HKD1_k127_308141_1 OmpW family K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000001848 166.0
HKD1_k127_308141_2 Belongs to the ompA family K03286 - - 0.0000000006813 70.0
HKD1_k127_3083622_0 Pfam Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 358.0
HKD1_k127_3083622_1 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.0000000000000000000000000000000000000000000002756 177.0
HKD1_k127_3085303_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 4.344e-275 863.0
HKD1_k127_3085303_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.488e-258 806.0
HKD1_k127_3085303_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 453.0
HKD1_k127_3085303_3 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 438.0
HKD1_k127_3085303_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000002176 273.0
HKD1_k127_3085303_5 - - - - 0.000000001069 68.0
HKD1_k127_308748_0 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 484.0
HKD1_k127_308748_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001578 232.0
HKD1_k127_308748_2 Domain of unknown function (DUF4377) - - - 0.0000000000000000000000000000000000000000000000001619 188.0
HKD1_k127_308748_3 Protein of unknown function (DUF1428) - - - 0.0000000000000000000000000000000000005194 150.0
HKD1_k127_308748_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000006435 80.0
HKD1_k127_3088782_0 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 530.0
HKD1_k127_3088782_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 295.0
HKD1_k127_3088782_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.00000000000000000000000000000000000000000000000000000000000002423 222.0
HKD1_k127_3088782_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000377 146.0
HKD1_k127_3088782_4 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000005027 114.0
HKD1_k127_3088782_5 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.00000000000000000004781 94.0
HKD1_k127_3100075_1 PFAM Negative transcriptional regulator K07734 - - 0.000000000301 62.0
HKD1_k127_3100075_2 Predicted membrane protein (DUF2157) - - - 0.00000007979 63.0
HKD1_k127_3112950_0 Amino acid permease - - - 5.304e-211 676.0
HKD1_k127_3112950_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 289.0
HKD1_k127_3112950_2 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000002347 134.0
HKD1_k127_3125616_0 ABC-type multidrug transport system ATPase and permease K06147 - - 3.823e-237 743.0
HKD1_k127_3125616_1 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.000000000000000000000000000000000000000000000000000006318 192.0
HKD1_k127_3142740_0 Dehydrogenase K17760 - 1.1.9.1 3.143e-245 771.0
HKD1_k127_3142740_1 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000000009691 201.0
HKD1_k127_3143454_0 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 0.0 1230.0
HKD1_k127_3143454_1 serine dehydratase beta chain K01752 - 4.3.1.17 2.265e-238 749.0
HKD1_k127_3143454_2 Tfp pilus assembly protein FimV - - - 1.071e-198 627.0
HKD1_k127_3143454_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 571.0
HKD1_k127_3143454_4 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 548.0
HKD1_k127_3143454_5 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 450.0
HKD1_k127_3143454_6 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 340.0
HKD1_k127_3143454_7 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000001102 202.0
HKD1_k127_3143454_8 Protein conserved in bacteria - - - 0.0000000000000005244 81.0
HKD1_k127_3144791_0 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 381.0
HKD1_k127_3144791_1 PQQ enzyme repeat K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 379.0
HKD1_k127_3144791_10 metal cluster binding K06940,K18475 - - 0.00000000000000000000000008371 119.0
HKD1_k127_3144791_11 pfam nudix - - - 0.0000000000000000001326 89.0
HKD1_k127_3144791_2 Catechol dioxygenase N terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 351.0
HKD1_k127_3144791_3 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 332.0
HKD1_k127_3144791_4 methyltransferase activity K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006234 277.0
HKD1_k127_3144791_5 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000001094 249.0
HKD1_k127_3144791_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000631 200.0
HKD1_k127_3144791_7 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000128 197.0
HKD1_k127_3144791_8 - - - - 0.00000000000000000000000000000000000000000000003498 175.0
HKD1_k127_3144791_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000009547 120.0
HKD1_k127_3147017_0 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 337.0
HKD1_k127_3147017_1 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 313.0
HKD1_k127_3147017_2 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000003675 218.0
HKD1_k127_3147017_3 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000000000001316 139.0
HKD1_k127_3147017_4 Protein of unknown function (DUF3301) - - - 0.0000000000000003939 82.0
HKD1_k127_3147017_5 small protein containing a coiled-coil domain - - - 0.0000000000000005323 81.0
HKD1_k127_3147436_0 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 7.543e-257 803.0
HKD1_k127_3147436_1 glutamate synthase K00284 - 1.4.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000275 264.0
HKD1_k127_3159283_0 FAD dependent oxidoreductase central domain - - - 0.0 1142.0
HKD1_k127_3159283_1 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 482.0
HKD1_k127_3159283_2 PFAM helix-turn-helix- domain containing protein, AraC type K21826 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 404.0
HKD1_k127_3159283_3 Methyltransferase K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000001789 188.0
HKD1_k127_3164004_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.613e-263 822.0
HKD1_k127_3164004_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 311.0
HKD1_k127_3164004_2 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003954 261.0
HKD1_k127_3164004_3 Belongs to the long-chain O-acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000007224 244.0
HKD1_k127_3203240_0 Cytochrome c-type biogenesis protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 400.0
HKD1_k127_3203240_1 COG0526 Thiol-disulfide isomerase and thioredoxins K02199 - - 0.00000000000000000000000000000000000000000000000000000000001592 211.0
HKD1_k127_3203240_2 MaoC like domain - - - 0.00000000000000000000000000000000000000002824 164.0
HKD1_k127_3203240_3 Cytochrome C biogenesis K02200 - - 0.000000000000000000000000000000006084 142.0
HKD1_k127_3203240_4 Protein tyrosine serine phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000001096 136.0
HKD1_k127_3203240_5 subunit of a heme lyase K02200 - - 0.00000000000000000000000000002342 130.0
HKD1_k127_3203240_6 bacterial OsmY and nodulation domain K04065 - - 0.0000000002279 72.0
HKD1_k127_3203240_7 bacterial OsmY and nodulation domain K04065 - - 0.0000000003042 71.0
HKD1_k127_3207367_0 PCRF K02835 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 480.0
HKD1_k127_3207367_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 420.0
HKD1_k127_3207367_2 Flavin-binding monooxygenase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 394.0
HKD1_k127_3207367_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006504 273.0
HKD1_k127_3207367_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000004673 261.0
HKD1_k127_3207367_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000299 255.0
HKD1_k127_3207367_6 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000001091 254.0
HKD1_k127_3207367_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000002242 221.0
HKD1_k127_3207367_8 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0010876,GO:0016020,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0034613,GO:0042157,GO:0042277,GO:0043170,GO:0044238,GO:0044462,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0051668,GO:0070727,GO:0071704,GO:0071723,GO:0071944,GO:0072657,GO:1901564 - 0.0000000000000000000001906 106.0
HKD1_k127_3234308_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1567.0
HKD1_k127_3234308_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 608.0
HKD1_k127_3234308_10 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 324.0
HKD1_k127_3234308_11 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 325.0
HKD1_k127_3234308_12 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 318.0
HKD1_k127_3234308_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 317.0
HKD1_k127_3234308_14 diguanylate cyclase K13069 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 289.0
HKD1_k127_3234308_15 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005602 254.0
HKD1_k127_3234308_16 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000006087 233.0
HKD1_k127_3234308_17 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000001823 230.0
HKD1_k127_3234308_18 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000002207 222.0
HKD1_k127_3234308_19 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000006791 222.0
HKD1_k127_3234308_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 601.0
HKD1_k127_3234308_20 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000008691 196.0
HKD1_k127_3234308_21 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K13628 - - 0.000000000000000000000000000000000000000001877 158.0
HKD1_k127_3234308_22 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000005737 164.0
HKD1_k127_3234308_23 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000000008126 164.0
HKD1_k127_3234308_24 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000001302 142.0
HKD1_k127_3234308_25 preprotein translocase subunit YajC K03210 - - 0.0000000000000000000000000000002325 132.0
HKD1_k127_3234308_26 Tetratricopeptide repeat-like domain - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 - 0.00000000000000000000000000001071 130.0
HKD1_k127_3234308_27 PDZ domain - - - 0.000000000000000000000003657 116.0
HKD1_k127_3234308_28 Helix-turn-helix domain K15539 - - 0.000000000000000009902 96.0
HKD1_k127_3234308_29 NifU-like N terminal domain - - - 0.00001018 53.0
HKD1_k127_3234308_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 531.0
HKD1_k127_3234308_4 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 507.0
HKD1_k127_3234308_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 467.0
HKD1_k127_3234308_6 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 442.0
HKD1_k127_3234308_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 422.0
HKD1_k127_3234308_8 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 386.0
HKD1_k127_3234308_9 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 337.0
HKD1_k127_3235182_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 395.0
HKD1_k127_3235182_1 AIR synthase related protein, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 321.0
HKD1_k127_3235182_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000008971 147.0
HKD1_k127_3242687_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 386.0
HKD1_k127_3242687_1 COG1073 Hydrolases of the alpha beta superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009017 263.0
HKD1_k127_3269979_0 COG5598 Trimethylamine corrinoid methyltransferase K14083 - 2.1.1.250 1.667e-233 737.0
HKD1_k127_3269979_1 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.00000000000000000000000000001729 123.0
HKD1_k127_3269979_2 belongs to the aldehyde dehydrogenase family K09472 - 1.2.1.99 0.00000000000002675 81.0
HKD1_k127_3271837_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 470.0
HKD1_k127_3271837_1 transporter, permease K02033,K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 391.0
HKD1_k127_3271837_2 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 344.0
HKD1_k127_3271837_3 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 319.0
HKD1_k127_3271837_4 Oligopeptide/dipeptide transporter, C-terminal region K10823 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000001065 253.0
HKD1_k127_3271837_5 REDY-like protein HapK - - - 0.00000000000000000000000000000006966 128.0
HKD1_k127_3271837_6 breast cancer carboxy-terminal domain K01972 - 6.5.1.2 0.0000000000000000000000000000006647 125.0
HKD1_k127_3271837_7 lactoylglutathione lyase activity - - - 0.00003744 48.0
HKD1_k127_328316_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1043.0
HKD1_k127_328316_1 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 597.0
HKD1_k127_328316_2 COG0209 Ribonucleotide reductase, alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 314.0
HKD1_k127_328316_3 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000005765 186.0
HKD1_k127_328316_4 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000007924 160.0
HKD1_k127_328316_5 Phospholipid-binding protein K06910 - - 0.0000000000000000000000003163 105.0
HKD1_k127_3305451_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 625.0
HKD1_k127_3305451_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K13614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 599.0
HKD1_k127_3305451_2 PFAM Cytochrome P450 K14338 - 1.14.14.1,1.6.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 396.0
HKD1_k127_3305451_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 392.0
HKD1_k127_3305451_4 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 306.0
HKD1_k127_3305451_5 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000002412 272.0
HKD1_k127_3305451_6 Domain of unknown function (DUF374) - - - 0.000000000000000000000000000000000000000000005684 184.0
HKD1_k127_3305451_7 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000008322 171.0
HKD1_k127_3305451_8 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000004141 123.0
HKD1_k127_3305451_9 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000001739 64.0
HKD1_k127_3323430_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 404.0
HKD1_k127_3323430_1 Phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 328.0
HKD1_k127_3347456_0 receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 383.0
HKD1_k127_3347456_1 adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001887 260.0
HKD1_k127_3347456_2 Periplasmic binding protein K02016,K06858 - - 0.0000000000000000000000000000000000000000000000000000000000000001062 238.0
HKD1_k127_3347456_3 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.1.10 0.00000000000000000000000002628 117.0
HKD1_k127_3380700_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 2.577e-211 685.0
HKD1_k127_3380700_1 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002612 279.0
HKD1_k127_3380700_2 Low molecular weight phosphotyrosine protein phosphatase K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000001051 111.0
HKD1_k127_3389748_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000891 307.0
HKD1_k127_3414450_0 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 499.0
HKD1_k127_3414450_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 458.0
HKD1_k127_3414450_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000001481 173.0
HKD1_k127_3414450_3 Nitroreductase family - - - 0.000000000000000000000000000000000001369 142.0
HKD1_k127_341945_0 Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 334.0
HKD1_k127_341945_1 HD domain - - - 0.000000000000000000000112 109.0
HKD1_k127_341945_2 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000001782 81.0
HKD1_k127_341945_3 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.00007062 45.0
HKD1_k127_342191_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 5.995e-212 668.0
HKD1_k127_342191_1 AcnD-accessory protein PrpF K09788 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 526.0
HKD1_k127_342191_2 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 345.0
HKD1_k127_342191_3 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000006133 212.0
HKD1_k127_342191_4 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000001434 197.0
HKD1_k127_342191_5 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000006362 80.0
HKD1_k127_3425024_0 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 297.0
HKD1_k127_3425024_1 Tyrosine-protein kinase, subgroup, catalytic domain K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 287.0
HKD1_k127_3425024_2 TonB family K03832 - - 0.0000000000000009598 84.0
HKD1_k127_3425024_3 Belongs to the ompA family K03640 - - 0.00000000000000365 82.0
HKD1_k127_346_0 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 449.0
HKD1_k127_346_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 422.0
HKD1_k127_346_2 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 340.0
HKD1_k127_346_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 289.0
HKD1_k127_346_4 membrane transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001267 261.0
HKD1_k127_346_5 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000001342 201.0
HKD1_k127_346_6 Belongs to the TPP enzyme family - - - 0.00000007335 54.0
HKD1_k127_3473057_0 Protein of unknown function (DUF3604) - - - 0.0 1078.0
HKD1_k127_3473057_1 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 487.0
HKD1_k127_3473057_2 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 473.0
HKD1_k127_3473057_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 411.0
HKD1_k127_3473057_4 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 325.0
HKD1_k127_3477549_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1323.0
HKD1_k127_3477549_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 428.0
HKD1_k127_3478959_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 375.0
HKD1_k127_3478959_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000005765 201.0
HKD1_k127_3478959_2 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000001248 153.0
HKD1_k127_3478959_3 PFAM Type II secretion system F domain K02653 - - 0.0000000008337 59.0
HKD1_k127_3504551_0 Homospermidine synthase K00808 - 2.5.1.44 4.491e-231 723.0
HKD1_k127_3504551_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 4.294e-199 647.0
HKD1_k127_3504551_10 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000000001593 128.0
HKD1_k127_3504551_11 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000004454 109.0
HKD1_k127_3504551_12 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000007452 111.0
HKD1_k127_3504551_13 membrane - - - 0.000000000000000000000001732 105.0
HKD1_k127_3504551_2 Protein of unknown function (DUF1838) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 337.0
HKD1_k127_3504551_3 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 307.0
HKD1_k127_3504551_4 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001073 264.0
HKD1_k127_3504551_5 Methyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000608 266.0
HKD1_k127_3504551_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000193 216.0
HKD1_k127_3504551_7 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000001151 213.0
HKD1_k127_3504551_8 Protein of unknown function (DUF1134) - - - 0.0000000000000000000000000000000000000000000000000000002467 196.0
HKD1_k127_3504551_9 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000002177 159.0
HKD1_k127_3516777_0 Heat shock 70 kDa protein K04043 - - 3.273e-316 979.0
HKD1_k127_3516777_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 507.0
HKD1_k127_3516777_2 Dihydrodipicolinate reductase, C-terminus K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004856 272.0
HKD1_k127_3516777_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000006889 93.0
HKD1_k127_3516777_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000002635 55.0
HKD1_k127_352415_0 PQQ enzyme repeat K17760 - 1.1.9.1 7.604e-290 908.0
HKD1_k127_352415_1 TonB dependent receptor - - - 1.263e-287 923.0
HKD1_k127_352415_10 Planctomycete cytochrome C - - - 0.0000000000000000000000000000000000007996 142.0
HKD1_k127_352415_11 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000248 118.0
HKD1_k127_352415_12 Transcriptional regulatory protein, C terminal - - - 0.0000000000002529 74.0
HKD1_k127_352415_2 Dehydratase family K01687 - 4.2.1.9 1.091e-267 837.0
HKD1_k127_352415_3 COG3420 Nitrous oxidase accessory protein - - - 4.555e-226 710.0
HKD1_k127_352415_4 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K20034 - 6.2.1.44 3.88e-202 643.0
HKD1_k127_352415_5 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 560.0
HKD1_k127_352415_6 COG1858 Cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 541.0
HKD1_k127_352415_7 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 443.0
HKD1_k127_352415_8 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 375.0
HKD1_k127_352415_9 COG2863 Cytochrome c553 - - - 0.000000000000000000000000000000000000000000000000002156 189.0
HKD1_k127_3594760_0 Peptidase dimerisation domain - - - 1.896e-205 644.0
HKD1_k127_3594760_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 591.0
HKD1_k127_3594760_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007662 287.0
HKD1_k127_3594760_3 - - - - 0.0000000000000000000000000000000000000000000000000000004045 202.0
HKD1_k127_3594760_4 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000001864 172.0
HKD1_k127_3594760_6 Alpha beta hydrolase - - - 0.000003682 48.0
HKD1_k127_3599594_0 ABC transporter - - - 1.805e-295 915.0
HKD1_k127_3599594_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.284e-208 656.0
HKD1_k127_3599594_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 382.0
HKD1_k127_3599594_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000002738 233.0
HKD1_k127_3599594_4 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000001307 229.0
HKD1_k127_3654718_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177,K16877 - 1.17.1.4,1.3.99.8 0.0 1242.0
HKD1_k127_3654718_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 428.0
HKD1_k127_3654718_2 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 417.0
HKD1_k127_3654718_3 VWA domain containing CoxE-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 394.0
HKD1_k127_3654718_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004826 275.0
HKD1_k127_3654718_5 YHS domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001867 254.0
HKD1_k127_3654718_6 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.00000000000000000000000000000000000000000000000000000000003597 214.0
HKD1_k127_3654718_7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000001083 109.0
HKD1_k127_3661244_0 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008742 578.0
HKD1_k127_3661244_1 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 437.0
HKD1_k127_3661244_2 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009674 345.0
HKD1_k127_3661244_3 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 306.0
HKD1_k127_3661244_4 Dehydrogenase K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 302.0
HKD1_k127_3661244_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000001594 170.0
HKD1_k127_3661244_6 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000002143 136.0
HKD1_k127_3661244_7 LysR substrate binding domain - - - 0.0000000004954 70.0
HKD1_k127_3693011_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 584.0
HKD1_k127_3693011_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 467.0
HKD1_k127_3693011_2 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 370.0
HKD1_k127_3693011_3 Dehydrogenase K15054 - 1.1.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003987 294.0
HKD1_k127_3693011_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003001 272.0
HKD1_k127_3710173_0 CoA-substrate-specific enzyme activase - - - 0.0 1750.0
HKD1_k127_3710173_1 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 551.0
HKD1_k127_3710173_10 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000000001254 120.0
HKD1_k127_3710173_11 Protein of unknown function (DUF535) K09824 - - 0.0000000000000000000000000003869 123.0
HKD1_k127_3710173_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 373.0
HKD1_k127_3710173_3 Histidine kinase K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 338.0
HKD1_k127_3710173_4 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002586 262.0
HKD1_k127_3710173_5 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002371 241.0
HKD1_k127_3710173_6 Membrane K08978 - - 0.0000000000000000000000000000000000000000000000000000000000000000004868 233.0
HKD1_k127_3710173_7 response regulator - - - 0.00000000000000000000000000000000000000000000000000000001026 205.0
HKD1_k127_3710173_8 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000000000000000000000002686 194.0
HKD1_k127_3710173_9 - - - - 0.000000000000000000000000000000000003977 143.0
HKD1_k127_375828_0 transposition K07497 - - 0.00000000000000000000003982 111.0
HKD1_k127_375828_1 transposition K07497 - - 0.000000000001275 75.0
HKD1_k127_375828_2 PFAM Integrase catalytic region - - - 0.00000000002931 76.0
HKD1_k127_376028_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.0 1041.0
HKD1_k127_376028_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 8.477e-231 728.0
HKD1_k127_376028_10 Transcriptional regulator K05800 - - 0.000000000000000000000000000000000000000000000001328 178.0
HKD1_k127_376028_11 Uncharacterised conserved protein (DUF2156) K07027,K14205 - 2.3.2.3 0.00000000000000000000000000000000000000000001483 174.0
HKD1_k127_376028_12 Putative adhesin - - - 0.00000000000000000000000000000000000000001695 170.0
HKD1_k127_376028_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000004344 153.0
HKD1_k127_376028_14 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000005975 151.0
HKD1_k127_376028_15 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000001202 138.0
HKD1_k127_376028_16 membrane - - - 0.000000000000000000000000003972 118.0
HKD1_k127_376028_17 Pfam:DUF46 - - - 0.000000000000000003064 92.0
HKD1_k127_376028_18 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.000000000000000006819 90.0
HKD1_k127_376028_19 - - - - 0.00000001439 64.0
HKD1_k127_376028_2 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 622.0
HKD1_k127_376028_20 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0006191 46.0
HKD1_k127_376028_3 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 534.0
HKD1_k127_376028_4 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 518.0
HKD1_k127_376028_5 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 386.0
HKD1_k127_376028_6 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 314.0
HKD1_k127_376028_7 Flavin containing amine oxidoreductase K06955 - - 0.00000000000000000000000000000000000000000000000000000000000000000002576 246.0
HKD1_k127_376028_8 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.000000000000000000000000000000000000000000000000000000000001078 216.0
HKD1_k127_376028_9 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component and related enzymes K09699 - 2.3.1.168 0.0000000000000000000000000000000000000000000000000000005469 204.0
HKD1_k127_378986_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008478 587.0
HKD1_k127_378986_1 in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008183 271.0
HKD1_k127_378986_2 Insecticidal toxin complex protein TcaC - - - 0.00000000000000000000000000000000000000000000000000000000000005886 235.0
HKD1_k127_3794006_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 372.0
HKD1_k127_3794006_1 MazG-like family - - - 0.00000000000000000000000000000000000000001895 155.0
HKD1_k127_3794006_2 - - - - 0.0000000000000000000000000000002429 139.0
HKD1_k127_3794006_3 nuclease K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.0000000000000000000000000000002555 130.0
HKD1_k127_3794006_5 - - - - 0.0005888 46.0
HKD1_k127_382031_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 532.0
HKD1_k127_382031_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 482.0
HKD1_k127_382031_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 409.0
HKD1_k127_382031_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000001568 230.0
HKD1_k127_382031_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000007412 206.0
HKD1_k127_382031_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000004625 148.0
HKD1_k127_382031_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000001166 162.0
HKD1_k127_389452_0 signal transduction histidine kinase K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 333.0
HKD1_k127_389452_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000007988 139.0
HKD1_k127_389452_2 penicillin-binding protein - - - 0.00000000627 65.0
HKD1_k127_389638_0 Belongs to the Orn Lys Arg decarboxylase class-II family K00928,K12526 - 2.7.2.4,4.1.1.20 2.037e-305 959.0
HKD1_k127_389638_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000001177 128.0
HKD1_k127_4031002_0 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 367.0
HKD1_k127_4031002_1 Alkyl hydroperoxide reductase K03387 - - 0.000000000000000000000000000000000000000000008192 164.0
HKD1_k127_4031002_2 Periplasmic or secreted lipoprotein - - - 0.0000000000007074 76.0
HKD1_k127_4031372_0 Short chain dehydrogenase - - - 1.518e-263 827.0
HKD1_k127_4031372_1 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 7.796e-262 834.0
HKD1_k127_4031372_10 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000002342 237.0
HKD1_k127_4031372_11 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000001593 203.0
HKD1_k127_4031372_12 lipid kinase, YegS Rv2252 BmrU family - - - 0.000000000000000000000000000000000000000000005417 178.0
HKD1_k127_4031372_13 - - - - 0.000000000000000000000000000000000000000002031 166.0
HKD1_k127_4031372_14 acetyltransferase - - - 0.0000000000000000000000000000000000577 153.0
HKD1_k127_4031372_15 Poly(hydroxyalcanoate) granule associated protein - - - 0.00000000000000001323 90.0
HKD1_k127_4031372_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 1.375e-238 749.0
HKD1_k127_4031372_3 FtsX-like permease family K02004 - - 5.699e-216 706.0
HKD1_k127_4031372_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K15022 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 515.0
HKD1_k127_4031372_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 477.0
HKD1_k127_4031372_6 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 434.0
HKD1_k127_4031372_7 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 381.0
HKD1_k127_4031372_8 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 299.0
HKD1_k127_4031372_9 PFAM transferase hexapeptide repeat containing protein K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 299.0
HKD1_k127_4032332_0 Aminomethyltransferase folate-binding domain K15066 - 2.1.1.341 5.962e-277 854.0
HKD1_k127_4032332_1 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 402.0
HKD1_k127_4032332_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000007218 187.0
HKD1_k127_4035340_0 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 2.351e-232 746.0
HKD1_k127_4035340_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.065e-198 627.0
HKD1_k127_4035340_10 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000001001 121.0
HKD1_k127_4035340_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 436.0
HKD1_k127_4035340_3 Zn-dependent protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 435.0
HKD1_k127_4035340_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 357.0
HKD1_k127_4035340_5 Pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 342.0
HKD1_k127_4035340_6 PFAM YicC-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005248 263.0
HKD1_k127_4035340_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000002266 240.0
HKD1_k127_4035340_8 - - - - 0.0000000000000000000000000000000000000000000000001997 183.0
HKD1_k127_4035340_9 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000002019 192.0
HKD1_k127_4041685_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 4.08e-207 670.0
HKD1_k127_4041685_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 457.0
HKD1_k127_4041685_10 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000003078 110.0
HKD1_k127_4041685_11 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000001718 112.0
HKD1_k127_4041685_2 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 432.0
HKD1_k127_4041685_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 351.0
HKD1_k127_4041685_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 334.0
HKD1_k127_4041685_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 332.0
HKD1_k127_4041685_6 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 300.0
HKD1_k127_4041685_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007249 250.0
HKD1_k127_4041685_8 Cytidylyltransferase family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000000000000000000000001872 192.0
HKD1_k127_4041685_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 0.00000000000000000000000000000000224 134.0
HKD1_k127_4047135_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1345.0
HKD1_k127_4047135_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 1.208e-263 827.0
HKD1_k127_4047135_10 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 341.0
HKD1_k127_4047135_11 Belongs to the 'phage' integrase family. XerC subfamily K03733 GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 346.0
HKD1_k127_4047135_12 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 331.0
HKD1_k127_4047135_13 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 326.0
HKD1_k127_4047135_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 317.0
HKD1_k127_4047135_15 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 316.0
HKD1_k127_4047135_16 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 308.0
HKD1_k127_4047135_17 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001526 291.0
HKD1_k127_4047135_18 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000139 275.0
HKD1_k127_4047135_19 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000007226 284.0
HKD1_k127_4047135_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 1.453e-204 650.0
HKD1_k127_4047135_20 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007781 268.0
HKD1_k127_4047135_21 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000004709 258.0
HKD1_k127_4047135_22 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009903 260.0
HKD1_k127_4047135_23 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000006406 258.0
HKD1_k127_4047135_24 Response regulator of the LytR AlgR family K08083 - - 0.000000000000000000000000000000000000000000000000000000000000000000005211 243.0
HKD1_k127_4047135_25 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000055 237.0
HKD1_k127_4047135_26 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000662 205.0
HKD1_k127_4047135_27 E3 Ubiquitin ligase - - - 0.0000000000000000000000000000000000000000000000000002488 197.0
HKD1_k127_4047135_28 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000009876 186.0
HKD1_k127_4047135_29 enzyme of heme biosynthesis K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000006562 196.0
HKD1_k127_4047135_3 Ammonium Transporter K03320 - - 2.205e-203 643.0
HKD1_k127_4047135_30 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000002964 197.0
HKD1_k127_4047135_31 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000001901 178.0
HKD1_k127_4047135_32 Indole-3-glycerol phosphate synthase K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.00000000000000000000000000000000000001057 163.0
HKD1_k127_4047135_33 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000001737 143.0
HKD1_k127_4047135_34 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000007321 136.0
HKD1_k127_4047135_35 protein conserved in bacteria K09921 - - 0.0000000000000000000000000000000008668 140.0
HKD1_k127_4047135_36 transcriptional - - - 0.0000000000000000000000000000004859 126.0
HKD1_k127_4047135_37 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000001915 119.0
HKD1_k127_4047135_38 Protein of unknown function (DUF2892) - - - 0.0000000000000000000009911 102.0
HKD1_k127_4047135_39 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000004836 101.0
HKD1_k127_4047135_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 611.0
HKD1_k127_4047135_40 enzyme of heme biosynthesis K02496,K13543 - 2.1.1.107,4.2.1.75 0.0000000000000000002375 100.0
HKD1_k127_4047135_41 Membrane fusogenic activity K09806 - - 0.0000000000000000003043 92.0
HKD1_k127_4047135_43 Glutathione S-transferase - - - 0.00003153 47.0
HKD1_k127_4047135_5 Fad linked oxidase K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 517.0
HKD1_k127_4047135_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 471.0
HKD1_k127_4047135_7 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 421.0
HKD1_k127_4047135_8 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 362.0
HKD1_k127_4047135_9 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 361.0
HKD1_k127_4056596_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1282.0
HKD1_k127_4056635_0 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 1.187e-247 789.0
HKD1_k127_4056635_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.606e-211 664.0
HKD1_k127_4056635_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 473.0
HKD1_k127_4056635_3 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 301.0
HKD1_k127_4056635_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001263 270.0
HKD1_k127_4056635_5 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000005036 233.0
HKD1_k127_4056635_6 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000002282 218.0
HKD1_k127_4056635_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000001765 155.0
HKD1_k127_4069460_0 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 555.0
HKD1_k127_4069460_1 response regulator receiver K02487,K06596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009205 484.0
HKD1_k127_4069460_10 cheY-homologous receiver domain K02658 - - 0.00000000000000000000000000000000000000003899 155.0
HKD1_k127_4069460_11 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000000003829 135.0
HKD1_k127_4069460_12 TIGRFAM TonB K03832 - - 0.00000000000000000000000000000002795 139.0
HKD1_k127_4069460_13 Type IV pili signal transduction protein PilI K02659 - - 0.00000000000000000000000000000003259 133.0
HKD1_k127_4069460_2 twitching motility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 415.0
HKD1_k127_4069460_3 COG0840 Methyl-accepting chemotaxis protein K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 412.0
HKD1_k127_4069460_4 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 393.0
HKD1_k127_4069460_5 Oxidoreductase FAD-binding domain K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 383.0
HKD1_k127_4069460_6 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 329.0
HKD1_k127_4069460_7 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 302.0
HKD1_k127_4069460_8 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000002981 235.0
HKD1_k127_4069460_9 response regulator K02657 - - 0.000000000000000000000000000000000000000000000000000000000001669 211.0
HKD1_k127_4076238_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1644.0
HKD1_k127_4076238_1 Sulfate permease family K03321 - - 7.977e-205 648.0
HKD1_k127_4076238_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 585.0
HKD1_k127_4076238_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 463.0
HKD1_k127_4076238_4 PFAM Patatin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 346.0
HKD1_k127_4076238_5 - - - - 0.0000000000000000000000000000000000000000000003891 173.0
HKD1_k127_4076238_6 - - - - 0.000000000000000000000000006687 116.0
HKD1_k127_4076238_7 - - - - 0.0000000000000008029 79.0
HKD1_k127_4079711_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 407.0
HKD1_k127_4079711_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 400.0
HKD1_k127_4079711_2 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 339.0
HKD1_k127_4090190_0 Beta-eliminating lyase K01667 - 4.1.99.1 2.706e-229 717.0
HKD1_k127_4090190_1 COGs COG5616 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 366.0
HKD1_k127_4090190_2 ChrR Cupin-like domain - - - 0.000000000004053 68.0
HKD1_k127_4090190_3 Protein of unknown function (DUF2845) - - - 0.0004929 49.0
HKD1_k127_4090359_0 Nickel-dependent hydrogenase K06281 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 6.1e-322 991.0
HKD1_k127_4090359_1 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 575.0
HKD1_k127_4090359_2 Prokaryotic cytochrome b561 K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 297.0
HKD1_k127_4090359_3 Hydrogenase maturation protease K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000322 224.0
HKD1_k127_4090359_4 HupH hydrogenase expression protein, C-terminal conserved region K03618 - - 0.0000000000000000000000000000000000000000000000000001012 198.0
HKD1_k127_4090359_5 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.00000000000000000000000000000000001373 144.0
HKD1_k127_4090359_6 Hydrogenase-1 expression protein HyaE - - - 0.000000000000002511 80.0
HKD1_k127_4098449_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 9.119e-225 717.0
HKD1_k127_4098449_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 573.0
HKD1_k127_4098449_10 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000001569 98.0
HKD1_k127_4098449_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 501.0
HKD1_k127_4098449_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 447.0
HKD1_k127_4098449_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 378.0
HKD1_k127_4098449_5 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 297.0
HKD1_k127_4098449_6 Aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006303 273.0
HKD1_k127_4098449_7 Glutamyl-tRNA amidotransferase K09117 - - 0.000000000000000000000000000000000000000000000004722 179.0
HKD1_k127_4098449_8 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000001345 162.0
HKD1_k127_4098449_9 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.000000000000000000000000000000000000007193 155.0
HKD1_k127_4118509_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.745e-199 632.0
HKD1_k127_4118509_1 fumarylacetoacetate (FAA) hydrolase K01555 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 609.0
HKD1_k127_4118509_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000004806 191.0
HKD1_k127_4118886_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 4.484e-288 897.0
HKD1_k127_4118886_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 465.0
HKD1_k127_4118886_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 382.0
HKD1_k127_4118886_3 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003188 266.0
HKD1_k127_4118886_4 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000533 243.0
HKD1_k127_4118886_5 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.00000000000000007989 91.0
HKD1_k127_4118886_6 Domain of unknown function DUF11 - - - 0.0006272 49.0
HKD1_k127_4122246_0 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 6.626e-286 895.0
HKD1_k127_4128050_0 Bacterial protein of unknown function (DUF885) - - - 2.911e-200 640.0
HKD1_k127_4128050_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.405e-199 632.0
HKD1_k127_4128050_10 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 308.0
HKD1_k127_4128050_11 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000001057 238.0
HKD1_k127_4128050_12 Ubiquinol--cytochrome c reductase - - - 0.0000000000000000000000000000000000000000000000000000001505 198.0
HKD1_k127_4128050_13 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000009664 150.0
HKD1_k127_4128050_14 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.000000000000000000000000000004277 128.0
HKD1_k127_4128050_15 Belongs to the UPF0149 family K09895 - - 0.00000000000000000000000001746 118.0
HKD1_k127_4128050_16 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000093 105.0
HKD1_k127_4128050_17 TIGRFAM TIGR02449 family protein K09892 - - 0.0000000002317 70.0
HKD1_k127_4128050_18 Domain of unknown function (DUF4440) - - - 0.0000000008085 64.0
HKD1_k127_4128050_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 3.212e-195 623.0
HKD1_k127_4128050_3 acyl-CoA dehydrogenase activity K09456 - - 3.171e-194 626.0
HKD1_k127_4128050_4 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 597.0
HKD1_k127_4128050_5 4Fe-4S dicluster domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 458.0
HKD1_k127_4128050_6 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 388.0
HKD1_k127_4128050_7 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 372.0
HKD1_k127_4128050_8 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 356.0
HKD1_k127_4128050_9 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K18800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 332.0
HKD1_k127_4142445_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 1.707e-227 714.0
HKD1_k127_4142445_1 Bacterial protein of unknown function (DUF885) - - - 4.424e-218 694.0
HKD1_k127_4142445_10 COG0811 Biopolymer transport proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 297.0
HKD1_k127_4142445_11 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001618 298.0
HKD1_k127_4142445_12 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000003529 208.0
HKD1_k127_4142445_13 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000001001 214.0
HKD1_k127_4142445_14 - - - - 0.00000000000000000000000000000000000000000000004741 180.0
HKD1_k127_4142445_15 - - - - 0.0000000000000000000000000000000000000000001273 176.0
HKD1_k127_4142445_16 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000000000000000000000000002383 150.0
HKD1_k127_4142445_17 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000001089 144.0
HKD1_k127_4142445_18 Alpha beta hydrolase - - - 0.0000000000000000000000000001845 124.0
HKD1_k127_4142445_19 Chromate transporter K07240 - - 0.0000000000000004062 82.0
HKD1_k127_4142445_2 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 504.0
HKD1_k127_4142445_20 Glutathione S-transferase, C-terminal domain - - - 0.00000000000002042 84.0
HKD1_k127_4142445_21 - - - - 0.00000000000005629 85.0
HKD1_k127_4142445_22 - - - - 0.0000000000001231 80.0
HKD1_k127_4142445_23 - - - - 0.000000000001126 80.0
HKD1_k127_4142445_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 486.0
HKD1_k127_4142445_4 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 426.0
HKD1_k127_4142445_5 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 423.0
HKD1_k127_4142445_6 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 388.0
HKD1_k127_4142445_7 von Willebrand factor (VWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 331.0
HKD1_k127_4142445_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 329.0
HKD1_k127_4142445_9 Secreted protein, containing von Willebrand factor (VWF) type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 338.0
HKD1_k127_4149186_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.562e-205 647.0
HKD1_k127_4149186_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005084 273.0
HKD1_k127_4149186_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001272 260.0
HKD1_k127_4149186_3 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000001534 174.0
HKD1_k127_4149186_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.0001485 45.0
HKD1_k127_4159610_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 356.0
HKD1_k127_4159610_1 sterol desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001039 272.0
HKD1_k127_4159610_2 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000001844 214.0
HKD1_k127_4159610_3 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000003216 157.0
HKD1_k127_4159610_4 membrane - - - 0.000000000000000000000000000000003708 131.0
HKD1_k127_4163289_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 497.0
HKD1_k127_4163289_1 COG1131 ABC-type multidrug transport system, ATPase component K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 416.0
HKD1_k127_4163289_10 - - - - 0.000007932 53.0
HKD1_k127_4163289_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 349.0
HKD1_k127_4163289_3 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 295.0
HKD1_k127_4163289_4 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000005787 247.0
HKD1_k127_4163289_5 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000002107 225.0
HKD1_k127_4163289_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000004146 238.0
HKD1_k127_4163289_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000002842 138.0
HKD1_k127_4163289_8 Methyltransferase FkbM domain - - - 0.00000000000000000000002341 116.0
HKD1_k127_4163289_9 membrane transporter protein K07090 - - 0.000000000000000000009179 96.0
HKD1_k127_4164403_0 Concanavalin A-like lectin/glucanases superfamily - - - 2.251e-306 959.0
HKD1_k127_4164403_1 - - - - 1.489e-227 716.0
HKD1_k127_4164403_10 Glutathione peroxidase - - - 0.000000000000000000000000000001838 128.0
HKD1_k127_4164403_11 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000005948 123.0
HKD1_k127_4164403_12 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000002539 121.0
HKD1_k127_4164403_13 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000002802 98.0
HKD1_k127_4164403_14 Tetratricopeptide repeat - - - 0.00000000000000001224 99.0
HKD1_k127_4164403_15 - - - - 0.000000000004935 76.0
HKD1_k127_4164403_2 Tetratricopeptide repeat - - - 3.675e-215 708.0
HKD1_k127_4164403_3 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component K00380,K14338 - 1.14.14.1,1.6.2.4,1.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 619.0
HKD1_k127_4164403_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 504.0
HKD1_k127_4164403_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 447.0
HKD1_k127_4164403_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 360.0
HKD1_k127_4164403_7 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000002112 232.0
HKD1_k127_4164403_8 - - - - 0.0000000000000000000000000000000000000000000000000000000001017 209.0
HKD1_k127_4164403_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000933 186.0
HKD1_k127_4173800_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1245.0
HKD1_k127_4173800_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 599.0
HKD1_k127_4173800_10 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 300.0
HKD1_k127_4173800_11 Belongs to the SUA5 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 283.0
HKD1_k127_4173800_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001709 271.0
HKD1_k127_4173800_13 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000002184 267.0
HKD1_k127_4173800_14 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000004331 239.0
HKD1_k127_4173800_15 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000006792 244.0
HKD1_k127_4173800_16 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000004889 195.0
HKD1_k127_4173800_17 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000003117 195.0
HKD1_k127_4173800_18 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000001104 190.0
HKD1_k127_4173800_19 YCII-related domain K09780 - - 0.0000000000000000000000000000000003096 134.0
HKD1_k127_4173800_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 538.0
HKD1_k127_4173800_20 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000002781 137.0
HKD1_k127_4173800_21 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000000000000002059 123.0
HKD1_k127_4173800_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 507.0
HKD1_k127_4173800_4 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 492.0
HKD1_k127_4173800_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 492.0
HKD1_k127_4173800_6 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007778 419.0
HKD1_k127_4173800_7 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 438.0
HKD1_k127_4173800_8 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 419.0
HKD1_k127_4173800_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 338.0
HKD1_k127_4177072_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 550.0
HKD1_k127_4177072_1 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 435.0
HKD1_k127_4177072_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 415.0
HKD1_k127_4177072_3 Serine dehydratase K01752 - 4.3.1.17 0.000000000000000000000000000000000000000003598 154.0
HKD1_k127_4183742_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 570.0
HKD1_k127_4183742_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 567.0
HKD1_k127_4183742_10 (FHA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000008507 225.0
HKD1_k127_4183742_11 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001859 186.0
HKD1_k127_4183742_12 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000009463 181.0
HKD1_k127_4183742_13 Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000003161 172.0
HKD1_k127_4183742_14 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000003097 163.0
HKD1_k127_4183742_15 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000001116 136.0
HKD1_k127_4183742_16 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001515 109.0
HKD1_k127_4183742_17 membrane - - - 0.00000000000000000001998 102.0
HKD1_k127_4183742_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 544.0
HKD1_k127_4183742_3 signal peptide peptidase K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 481.0
HKD1_k127_4183742_4 Mg2 and Co2 transporter CorB - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 463.0
HKD1_k127_4183742_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 373.0
HKD1_k127_4183742_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 376.0
HKD1_k127_4183742_7 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 322.0
HKD1_k127_4183742_8 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 305.0
HKD1_k127_4183742_9 phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000414 284.0
HKD1_k127_4188520_0 PFAM glycoside hydrolase family 39 K01198 - 3.2.1.37 9.036e-236 742.0
HKD1_k127_4188520_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342,K03703,K04096 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.000000000000000000000000000000000000000000000000000000001448 220.0
HKD1_k127_4188520_2 Dehydrogenase K00005 - 1.1.1.6 0.00001795 48.0
HKD1_k127_4221999_0 Immune inhibitor A peptidase M6 K09607 - - 0.0 1191.0
HKD1_k127_4221999_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 518.0
HKD1_k127_4233654_0 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000001098 234.0
HKD1_k127_4233654_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000001009 111.0
HKD1_k127_4237181_0 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 412.0
HKD1_k127_4237181_1 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007957 249.0
HKD1_k127_4237181_2 sulfur carrier activity K04085 - - 0.0000000002834 69.0
HKD1_k127_4281526_0 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 571.0
HKD1_k127_4281526_1 Cysteine synthase K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000001118 171.0
HKD1_k127_428752_0 acyl-CoA dehydrogenase K06445 GO:0003674,GO:0003824,GO:0003995,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 - 3.365e-244 771.0
HKD1_k127_428752_1 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 381.0
HKD1_k127_4320893_0 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 1.39e-266 835.0
HKD1_k127_4320893_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 1.767e-260 808.0
HKD1_k127_4320893_10 Diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000004194 123.0
HKD1_k127_4320893_11 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000001606 95.0
HKD1_k127_4320893_2 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 468.0
HKD1_k127_4320893_3 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 380.0
HKD1_k127_4320893_4 NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 335.0
HKD1_k127_4320893_5 glycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 307.0
HKD1_k127_4320893_6 ArsC family K00537 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000002464 224.0
HKD1_k127_4320893_7 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000002768 199.0
HKD1_k127_4320893_8 Trypsin - - - 0.0000000000000000000000000000000000000000001033 181.0
HKD1_k127_4320893_9 maturation - - - 0.0000000000000000000000000000000723 145.0
HKD1_k127_4320991_0 response regulator K02481,K07714,K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 310.0
HKD1_k127_4320991_1 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000006325 85.0
HKD1_k127_4321173_0 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 516.0
HKD1_k127_4321173_1 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 358.0
HKD1_k127_4321173_2 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 341.0
HKD1_k127_4336064_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 312.0
HKD1_k127_4336064_1 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000376 273.0
HKD1_k127_4336064_2 - - - - 0.000000000000000000000000000000000000000000000000000000000005198 211.0
HKD1_k127_4336064_3 - - - - 0.000000000000000000257 93.0
HKD1_k127_4339077_0 Efflux pump K03296,K18138,K18322 - - 0.0 1581.0
HKD1_k127_4339077_1 Outer membrane efflux protein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 527.0
HKD1_k127_4339077_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 478.0
HKD1_k127_4339077_3 E1-E2 ATPase K01535 - 3.6.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007783 278.0
HKD1_k127_4339077_4 BetI-type transcriptional repressor, C-terminal - - - 0.00000000000000000000000000003103 131.0
HKD1_k127_4339346_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 479.0
HKD1_k127_4339346_1 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 493.0
HKD1_k127_4339346_10 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000001191 205.0
HKD1_k127_4339346_11 PFAM ApaG domain protein K06195 - - 0.00000000000000000000000000000000000000000000000001893 184.0
HKD1_k127_4339346_12 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K06149 - - 0.000000000000000000000000001465 117.0
HKD1_k127_4339346_13 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000001014 93.0
HKD1_k127_4339346_14 Protein of unknown function (DUF493) K09158 - - 0.000000000000000001732 98.0
HKD1_k127_4339346_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 384.0
HKD1_k127_4339346_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 373.0
HKD1_k127_4339346_4 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 345.0
HKD1_k127_4339346_5 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 316.0
HKD1_k127_4339346_6 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00966,K00992 GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002766 283.0
HKD1_k127_4339346_7 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003736 278.0
HKD1_k127_4339346_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000001283 282.0
HKD1_k127_4339346_9 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000006568 255.0
HKD1_k127_4358278_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.97e-273 869.0
HKD1_k127_4358278_1 Protein of unknown function (DUF1343) - - - 1.02e-211 664.0
HKD1_k127_4358278_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.04e-210 664.0
HKD1_k127_4358278_3 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 6.101e-201 637.0
HKD1_k127_4358278_4 PFAM fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 469.0
HKD1_k127_4358278_5 Esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 343.0
HKD1_k127_4358278_6 FAD dependent oxidoreductase K09471 - - 0.000000000000000000000000000000000000000007167 154.0
HKD1_k127_4358278_7 - - - - 0.0000000000000000000000000000000002223 142.0
HKD1_k127_4358278_8 Outer membrane protein W K07275 - - 0.0001206 52.0
HKD1_k127_4367935_0 Bacterial extracellular solute-binding protein K15770 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 493.0
HKD1_k127_4367935_1 Belongs to the ABC transporter superfamily K10111 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 456.0
HKD1_k127_4367935_2 Alpha-amylase domain K01176 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 440.0
HKD1_k127_4367935_3 Sugar ABC transporter permease K10109,K15770,K15771 - - 0.0000000000000000000006861 107.0
HKD1_k127_4368095_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 591.0
HKD1_k127_4368095_1 Putative sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 323.0
HKD1_k127_4368095_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 317.0
HKD1_k127_4368095_3 PadR family transcriptional regulator K10947 - - 0.000000000000000000000000000000000001431 142.0
HKD1_k127_4368095_4 Water Stress and Hypersensitive response - - - 0.0000000000000000000008886 102.0
HKD1_k127_4394041_0 GMC oxidoreductase K00108 - 1.1.99.1 1.683e-282 879.0
HKD1_k127_4394041_1 FAD dependent oxidoreductase - - - 1.102e-219 727.0
HKD1_k127_4394041_10 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.000002897 49.0
HKD1_k127_4394041_2 cobalt chelatase K09883 - 6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 559.0
HKD1_k127_4394041_3 NADPH quinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 426.0
HKD1_k127_4394041_4 cobaltochelatase subunit CobS K09882 - 6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 396.0
HKD1_k127_4394041_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 371.0
HKD1_k127_4394041_6 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 363.0
HKD1_k127_4394041_7 KR domain K00046,K00059 - 1.1.1.100,1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 330.0
HKD1_k127_4394041_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 322.0
HKD1_k127_4394041_9 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000001187 167.0
HKD1_k127_4403065_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 593.0
HKD1_k127_4403065_1 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 371.0
HKD1_k127_4403065_2 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 353.0
HKD1_k127_4403065_3 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000256 199.0
HKD1_k127_4403065_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000009552 156.0
HKD1_k127_4450190_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 3.858e-210 661.0
HKD1_k127_4450190_1 response regulator receiver K02487,K06596 - - 1.392e-202 646.0
HKD1_k127_4450190_2 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000001893 267.0
HKD1_k127_4450190_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000001298 236.0
HKD1_k127_4450190_4 chemotaxis signal transduction protein K06598 - - 0.00000000000000000000000742 106.0
HKD1_k127_4450190_5 Membrane protein required for beta-lactamase induction K03807 - - 0.0000002029 61.0
HKD1_k127_4451049_0 FAD linked oxidase domain protein - - - 0.0 1173.0
HKD1_k127_4466116_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1353.0
HKD1_k127_4466116_1 Diguanylate cyclase - - - 3.522e-199 661.0
HKD1_k127_4466116_10 dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes) K00382 K00382 - 1.8.1.4 0.00000000000000000000000006704 110.0
HKD1_k127_4466116_11 Fe-S protein K06938 - - 0.00000000002976 66.0
HKD1_k127_4466116_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 475.0
HKD1_k127_4466116_3 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 361.0
HKD1_k127_4466116_4 quinolinate catabolic process K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 347.0
HKD1_k127_4466116_5 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004134 284.0
HKD1_k127_4466116_6 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005869 279.0
HKD1_k127_4466116_7 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000009992 235.0
HKD1_k127_4466116_8 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000002301 170.0
HKD1_k127_4466116_9 Domain of unknown function (DUF374) - - - 0.00000000000000000000000000000000000000000007615 168.0
HKD1_k127_4491276_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1110.0
HKD1_k127_4491276_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 3.173e-309 963.0
HKD1_k127_4491276_10 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 359.0
HKD1_k127_4491276_11 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009404 340.0
HKD1_k127_4491276_12 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 322.0
HKD1_k127_4491276_13 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 312.0
HKD1_k127_4491276_14 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 289.0
HKD1_k127_4491276_15 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006746 276.0
HKD1_k127_4491276_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001985 247.0
HKD1_k127_4491276_17 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000003457 221.0
HKD1_k127_4491276_18 PFAM MucB RseB K03598 - - 0.00000000000000000000000000000000000000000000000000212 194.0
HKD1_k127_4491276_19 CYTH domain protein K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000009319 177.0
HKD1_k127_4491276_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.076e-295 915.0
HKD1_k127_4491276_20 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000006695 179.0
HKD1_k127_4491276_21 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication K06980 GO:0003674,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0019842,GO:0022607,GO:0031163,GO:0031406,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071840,GO:0072341,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000007639 157.0
HKD1_k127_4491276_22 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.000000000000000000000000000005918 123.0
HKD1_k127_4491276_23 protein conserved in bacteria - - - 0.00000000000000000000000000002216 126.0
HKD1_k127_4491276_24 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000116 110.0
HKD1_k127_4491276_25 succinate dehydrogenase - - - 0.0000000000000000000002365 113.0
HKD1_k127_4491276_26 Diguanylate cyclase - - - 0.000000000000000297 89.0
HKD1_k127_4491276_27 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000002056 76.0
HKD1_k127_4491276_28 Domain of unknown function (DUF4845) - - - 0.00000000002074 73.0
HKD1_k127_4491276_29 Protein of unknown function (DUF1674) - - - 0.00000000008419 73.0
HKD1_k127_4491276_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 6.63e-210 664.0
HKD1_k127_4491276_30 - - - - 0.0000000005895 73.0
HKD1_k127_4491276_31 PFAM glutaredoxin 2 - - - 0.00000000286 66.0
HKD1_k127_4491276_32 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.0000002374 58.0
HKD1_k127_4491276_33 Negative regulator of sigma E activity - - - 0.00002172 53.0
HKD1_k127_4491276_4 COG0608 Single-stranded DNA-specific exonuclease K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 576.0
HKD1_k127_4491276_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 512.0
HKD1_k127_4491276_6 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 466.0
HKD1_k127_4491276_7 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 438.0
HKD1_k127_4491276_8 Lipoprotein releasing system transmembrane protein K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 420.0
HKD1_k127_4491276_9 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 391.0
HKD1_k127_4502055_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 4.683e-218 704.0
HKD1_k127_4502055_1 Aldehyde dehydrogenase family - - - 2.806e-214 677.0
HKD1_k127_4502055_2 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 557.0
HKD1_k127_4502055_3 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 460.0
HKD1_k127_4502055_4 Peptidase C26 K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000005656 166.0
HKD1_k127_45220_0 TonB-dependent receptor plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 561.0
HKD1_k127_45220_1 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000009574 244.0
HKD1_k127_45220_2 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.000000000000000000000000000000000000000000000000000000002982 205.0
HKD1_k127_45220_3 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000008182 104.0
HKD1_k127_45220_4 Rieske-like [2Fe-2S] domain - - - 0.0000000000000000005066 91.0
HKD1_k127_45220_5 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.000000000000000443 83.0
HKD1_k127_45220_6 YKOF-related Family - - - 0.0000000000001052 81.0
HKD1_k127_45220_7 nicotinamide mononucleotide transporter K03811 - - 0.0000000000858 68.0
HKD1_k127_4522642_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 9.057e-226 708.0
HKD1_k127_4522642_1 pfam mofrl K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 321.0
HKD1_k127_4522642_2 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000003025 214.0
HKD1_k127_4522642_3 membrane protein, required for colicin V production K03558 - - 0.00000000000000000001884 98.0
HKD1_k127_4537132_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.364e-281 891.0
HKD1_k127_4537132_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 530.0
HKD1_k127_4541994_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 5.15e-219 716.0
HKD1_k127_4541994_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 297.0
HKD1_k127_4541994_2 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001092 230.0
HKD1_k127_4541994_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000001996 173.0
HKD1_k127_4541994_4 PFAM Hydantoinase oxoprolinase K01469 - 3.5.2.9 0.000000000000000000000000000000000000000003819 159.0
HKD1_k127_4541994_5 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.000000000000000000000000000004194 123.0
HKD1_k127_4582199_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 534.0
HKD1_k127_4582199_1 Belongs to the CinA family K03743 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016811,GO:0019159 3.5.1.42 0.00000000000000000000000000000000000000000000006363 173.0
HKD1_k127_4582199_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000002739 132.0
HKD1_k127_4582199_3 Domain of unknown function (DUF4136) - - - 0.00000000000000000000001291 104.0
HKD1_k127_4582199_4 - - - - 0.0000000000000004836 85.0
HKD1_k127_4582199_5 - - - - 0.00000000000000123 83.0
HKD1_k127_4603910_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 5.892e-215 681.0
HKD1_k127_4603910_1 Belongs to the GcvT family K00315 - 1.5.8.4 8.463e-195 634.0
HKD1_k127_4603910_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000006262 66.0
HKD1_k127_4641659_0 heptosyltransferase K12982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 412.0
HKD1_k127_4641659_1 3-Deoxy-D-manno-octulosonic-acid transferase K02527 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 393.0
HKD1_k127_4641659_2 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.00000000000000000000000000000000000000000000000004536 187.0
HKD1_k127_4641659_3 type I secretion outer membrane protein, TolC K12340 - - 0.00000000000000000000000000005784 119.0
HKD1_k127_4641659_4 Zinc-finger domain - - - 0.000000007058 68.0
HKD1_k127_466437_0 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1070.0
HKD1_k127_4726257_0 Glycine cleavage T-protein C-terminal barrel domain K00302 - 1.5.3.1 0.0 1217.0
HKD1_k127_4726257_1 Sarcosine oxidase, gamma subunit family K00305 - 1.5.3.1 0.00000000000000000000000000000000000000001105 160.0
HKD1_k127_4726257_2 FAD dependent oxidoreductase central domain - - - 0.000000000001046 68.0
HKD1_k127_5032514_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.296e-315 984.0
HKD1_k127_5032514_1 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 576.0
HKD1_k127_504177_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000001194 188.0
HKD1_k127_504177_1 MAPEG family - - - 0.000000000000000000000000000000003709 133.0
HKD1_k127_504177_2 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000001437 121.0
HKD1_k127_504177_3 PFAM Membrane protein of K08972 - - 0.0000000000000000000000001332 117.0
HKD1_k127_50516_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 494.0
HKD1_k127_50516_1 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 322.0
HKD1_k127_50516_2 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 307.0
HKD1_k127_50516_3 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000000001258 247.0
HKD1_k127_5054269_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 3.302e-232 722.0
HKD1_k127_5054269_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 381.0
HKD1_k127_5054269_2 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.00000000000000000000000000000395 133.0
HKD1_k127_5056377_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 406.0
HKD1_k127_5056377_1 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001126 291.0
HKD1_k127_5056377_2 PFAM sulfatase K01133 - 3.1.6.6 0.00000000000000000001411 96.0
HKD1_k127_5061381_0 Aldehyde dehydrogenase family K00130,K00137 - 1.2.1.19,1.2.1.8 2.256e-232 741.0
HKD1_k127_5061381_1 Spermidine putrescine ABC transporter substrate-binding protein K02055 GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 608.0
HKD1_k127_5061381_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 417.0
HKD1_k127_5061381_3 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 397.0
HKD1_k127_5061381_4 PFAM peptidase M13 K07386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 397.0
HKD1_k127_5061381_5 ABC transporter (permease) K02053 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 348.0
HKD1_k127_5061381_6 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000001405 231.0
HKD1_k127_5061381_7 Cytochrome K12262 - - 0.0000000000000000000000000000000000000006709 154.0
HKD1_k127_5061381_8 YceI-like domain - - - 0.000000000000000000000000000000000000006155 159.0
HKD1_k127_5061381_9 - - - - 0.00000000000147 75.0
HKD1_k127_5079025_0 mannitol 2-dehydrogenase activity K11690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 518.0
HKD1_k127_5079025_1 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 475.0
HKD1_k127_5079025_10 - - - - 0.00000000000000000000000000000000000000000000000000002789 196.0
HKD1_k127_5079025_11 Domain of unknown function (DUF4396) - - - 0.000000000000000000000000000000000000000000000000003751 186.0
HKD1_k127_5079025_12 Allene oxide cyclase - - - 0.0000000000000000000000000000000000000002259 154.0
HKD1_k127_5079025_13 helix_turn_helix, mercury resistance K08365 - - 0.00000000000000000000000000000000008629 138.0
HKD1_k127_5079025_14 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000005995 124.0
HKD1_k127_5079025_16 - - - - 0.000009714 56.0
HKD1_k127_5079025_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 465.0
HKD1_k127_5079025_3 Biotin-lipoyl like K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 291.0
HKD1_k127_5079025_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003625 273.0
HKD1_k127_5079025_5 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009287 268.0
HKD1_k127_5079025_6 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000001825 233.0
HKD1_k127_5079025_7 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000002348 223.0
HKD1_k127_5079025_8 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000006624 227.0
HKD1_k127_5079025_9 lipocalin K03098 - - 0.000000000000000000000000000000000000000000000000000000295 199.0
HKD1_k127_5083552_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1224.0
HKD1_k127_5083552_1 Glucose dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 623.0
HKD1_k127_5083552_2 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 372.0
HKD1_k127_5083552_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 339.0
HKD1_k127_5083552_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 299.0
HKD1_k127_5083552_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000819 287.0
HKD1_k127_5083552_6 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000004171 188.0
HKD1_k127_5083552_7 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000002993 104.0
HKD1_k127_5096766_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 434.0
HKD1_k127_5096766_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 366.0
HKD1_k127_5096766_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 324.0
HKD1_k127_5096766_3 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 308.0
HKD1_k127_5096766_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000007829 160.0
HKD1_k127_5097332_0 Sulfotransferase domain K01014 - 2.8.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 287.0
HKD1_k127_5097332_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002701 250.0
HKD1_k127_5097332_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001133 246.0
HKD1_k127_5097332_3 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000004366 239.0
HKD1_k127_5097332_4 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000008171 188.0
HKD1_k127_5097332_5 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000001712 137.0
HKD1_k127_5097332_6 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000002215 139.0
HKD1_k127_5097332_7 - - - - 0.000351 51.0
HKD1_k127_5109107_0 Aminomethyltransferase folate-binding domain K15066 - 2.1.1.341 3.1e-219 691.0
HKD1_k127_5109107_1 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 370.0
HKD1_k127_5109107_2 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 353.0
HKD1_k127_5109107_3 Dehydrogenase E1 component K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 306.0
HKD1_k127_5109107_4 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000006977 161.0
HKD1_k127_5130260_0 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 342.0
HKD1_k127_5130260_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001056 282.0
HKD1_k127_5130260_2 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K07264 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016763,GO:0033692,GO:0034637,GO:0034645,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.2.43 0.00000000000000000000000000000000000000000000000000003154 209.0
HKD1_k127_5130260_3 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000002395 181.0
HKD1_k127_5130260_4 Phosphopantetheine attachment site - - - 0.000000000001072 77.0
HKD1_k127_5131947_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 2.958e-243 781.0
HKD1_k127_5132509_0 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 1.77e-276 869.0
HKD1_k127_5132509_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 447.0
HKD1_k127_5132509_2 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 376.0
HKD1_k127_5132509_3 helix_turn_helix, mercury resistance K19591 - - 0.00000000000000000000000000000000000000000000000000000000000007439 215.0
HKD1_k127_5132509_4 Heavy-metal-associated domain K07213 - - 0.000000000000006419 78.0
HKD1_k127_5132509_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000008931 52.0
HKD1_k127_5138070_0 Nicotinate phosphoribosyltransferase (NAPRTase) family K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 514.0
HKD1_k127_5138070_1 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 399.0
HKD1_k127_5138070_2 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000008557 184.0
HKD1_k127_5138070_3 Universal stress protein family K14055 - - 0.0000000000008957 71.0
HKD1_k127_5149067_0 MaoC like domain K18290 - 4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000002077 259.0
HKD1_k127_5149067_1 UTRA K03710 - - 0.000000000000000000000000000000000000000000004063 180.0
HKD1_k127_5149067_2 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000002438 136.0
HKD1_k127_5159050_0 Sulfatase K01130 - 3.1.6.1 2.271e-264 827.0
HKD1_k127_5159050_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 9.086e-224 717.0
HKD1_k127_5159050_10 - - - - 0.0000000004383 71.0
HKD1_k127_5159050_2 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 585.0
HKD1_k127_5159050_3 LysR substrate binding domain K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 509.0
HKD1_k127_5159050_4 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 402.0
HKD1_k127_5159050_5 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 366.0
HKD1_k127_5159050_6 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008992 241.0
HKD1_k127_5159050_7 Flavodoxin-like fold K19784 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006805,GO:0008150,GO:0008152,GO:0009410,GO:0009987,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0032553,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0052873,GO:0055114,GO:0070887,GO:0071466,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000003637 242.0
HKD1_k127_5159050_8 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000003487 209.0
HKD1_k127_5159050_9 elastin biosynthetic process K17686 GO:0000041,GO:0000166,GO:0000302,GO:0000303,GO:0000305,GO:0000902,GO:0000904,GO:0001101,GO:0001501,GO:0001505,GO:0001568,GO:0001666,GO:0001701,GO:0001775,GO:0001836,GO:0001889,GO:0001942,GO:0001944,GO:0001974,GO:0002009,GO:0002082,GO:0002164,GO:0002252,GO:0002263,GO:0002285,GO:0002286,GO:0002287,GO:0002292,GO:0002293,GO:0002294,GO:0002366,GO:0002376,GO:0002520,GO:0002521,GO:0003674,GO:0003824,GO:0004008,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005774,GO:0005783,GO:0005794,GO:0005798,GO:0005802,GO:0005829,GO:0005886,GO:0005902,GO:0005903,GO:0006082,GO:0006139,GO:0006140,GO:0006163,GO:0006464,GO:0006520,GO:0006568,GO:0006570,GO:0006576,GO:0006584,GO:0006586,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006801,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006875,GO:0006878,GO:0006915,GO:0006950,GO:0006955,GO:0006979,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007589,GO:0007591,GO:0007593,GO:0007595,GO:0007610,GO:0007626,GO:0008047,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008324,GO:0008361,GO:0008544,GO:0008637,GO:0009058,GO:0009059,GO:0009072,GO:0009100,GO:0009101,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009308,GO:0009628,GO:0009636,GO:0009653,GO:0009712,GO:0009713,GO:0009719,GO:0009790,GO:0009791,GO:0009792,GO:0009888,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0010042,GO:0010043,GO:0010155,GO:0010243,GO:0010273,GO:0010288,GO:0010468,GO:0010591,GO:0010592,GO:0010941,GO:0010959,GO:0012501,GO:0012505,GO:0012506,GO:0014910,GO:0014911,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015677,GO:0015679,GO:0016020,GO:0016021,GO:0016043,GO:0016323,GO:0016324,GO:0016358,GO:0016462,GO:0016530,GO:0016531,GO:0016532,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017016,GO:0017048,GO:0017076,GO:0017111,GO:0017144,GO:0018193,GO:0018205,GO:0018958,GO:0019219,GO:0019220,GO:0019222,GO:0019430,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019725,GO:0019752,GO:0019829,GO:0019899,GO:0021533,GO:0021549,GO:0021575,GO:0021587,GO:0021680,GO:0021692,GO:0021694,GO:0021695,GO:0021696,GO:0021697,GO:0021700,GO:0021702,GO:0021859,GO:0021860,GO:0021872,GO:0021879,GO:0021884,GO:0021953,GO:0021954,GO:0022008,GO:0022037,GO:0022404,GO:0022405,GO:0022607,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0022898,GO:0023052,GO:0030001,GO:0030003,GO:0030030,GO:0030097,GO:0030098,GO:0030133,GO:0030135,GO:0030136,GO:0030139,GO:0030140,GO:0030141,GO:0030154,GO:0030182,GO:0030198,GO:0030199,GO:0030217,GO:0030234,GO:0030323,GO:0030324,GO:0030334,GO:0030335,GO:0030554,GO:0030659,GO:0030666,GO:0030670,GO:0030879,GO:0030900,GO:0030902,GO:0031069,GO:0031090,GO:0031175,GO:0031224,GO:0031252,GO:0031253,GO:0031267,GO:0031323,GO:0031344,GO:0031346,GO:0031410,GO:0031526,GO:0031982,GO:0031984,GO:0032025,GO:0032409,GO:0032412,GO:0032501,GO:0032502,GO:0032535,GO:0032553,GO:0032555,GO:0032559,GO:0032767,GO:0032879,GO:0032989,GO:0032990,GO:0033554,GO:0034220,GO:0034599,GO:0034614,GO:0034641,GO:0034645,GO:0034756,GO:0034757,GO:0034759,GO:0034760,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0035295,GO:0035434,GO:0035639,GO:0035710,GO:0036094,GO:0036119,GO:0036120,GO:0036211,GO:0036293,GO:0036294,GO:0036477,GO:0040012,GO:0040017,GO:0042093,GO:0042110,GO:0042127,GO:0042133,GO:0042221,GO:0042303,GO:0042325,GO:0042335,GO:0042414,GO:0042415,GO:0042417,GO:0042421,GO:0042423,GO:0042428,GO:0042430,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0042633,GO:0042981,GO:0042995,GO:0043005,GO:0043009,GO:0043025,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043200,GO:0043204,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043269,GO:0043271,GO:0043367,GO:0043412,GO:0043436,GO:0043467,GO:0043473,GO:0043492,GO:0043523,GO:0043524,GO:0043588,GO:0043682,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044092,GO:0044093,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045121,GO:0045177,GO:0045321,GO:0045335,GO:0045793,GO:0046034,GO:0046189,GO:0046483,GO:0046631,GO:0046632,GO:0046649,GO:0046677,GO:0046686,GO:0046688,GO:0046872,GO:0046873,GO:0046903,GO:0046914,GO:0046915,GO:0046916,GO:0048066,GO:0048067,GO:0048085,GO:0048251,GO:0048286,GO:0048365,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048729,GO:0048730,GO:0048731,GO:0048732,GO:0048771,GO:0048812,GO:0048813,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050678,GO:0050679,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050878,GO:0050896,GO:0051020,GO:0051049,GO:0051051,GO:0051087,GO:0051128,GO:0051130,GO:0051171,GO:0051174,GO:0051179,GO:0051216,GO:0051234,GO:0051270,GO:0051272,GO:0051341,GO:0051353,GO:0051541,GO:0051542,GO:0051716,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0055086,GO:0060003,GO:0060255,GO:0060322,GO:0060429,GO:0060491,GO:0060541,GO:0060548,GO:0061008,GO:0061448,GO:0061687,GO:0062012,GO:0065007,GO:0065008,GO:0065009,GO:0070482,GO:0070848,GO:0070887,GO:0071229,GO:0071230,GO:0071236,GO:0071241,GO:0071248,GO:0071276,GO:0071279,GO:0071280,GO:0071281,GO:0071284,GO:0071310,GO:0071363,GO:0071417,GO:0071450,GO:0071451,GO:0071453,GO:0071456,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0072358,GO:0072359,GO:0072521,GO:0072593,GO:0080090,GO:0080134,GO:0085029,GO:0090066,GO:0090662,GO:0097159,GO:0097164,GO:0097190,GO:0097237,GO:0097367,GO:0097435,GO:0097458,GO:0097501,GO:0097708,GO:0098588,GO:0098589,GO:0098590,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:0098772,GO:0098773,GO:0098791,GO:0098805,GO:0098857,GO:0098858,GO:0098862,GO:0098869,GO:0099131,GO:0099132,GO:0099503,GO:0120025,GO:0120032,GO:0120034,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0140104,GO:1900542,GO:1901135,GO:1901137,GO:1901160,GO:1901214,GO:1901215,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901615,GO:1901617,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902743,GO:1902745,GO:1903034,GO:1903036,GO:1903136,GO:1903578,GO:1904062,GO:1904063,GO:1904732,GO:1904752,GO:1904754,GO:1904959,GO:1990169,GO:1990748,GO:2000145,GO:2000147 3.6.3.54 0.0000000000006201 74.0
HKD1_k127_5168136_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 588.0
HKD1_k127_5168136_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 344.0
HKD1_k127_5168136_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000001856 147.0
HKD1_k127_5168136_3 Integral membrane protein (DUF2244) - - - 0.000000000000000000003394 100.0
HKD1_k127_5168834_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1097.0
HKD1_k127_5168834_1 Domain of Unknown Function (DUF349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 547.0
HKD1_k127_5168834_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000002843 201.0
HKD1_k127_5168834_3 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000611 108.0
HKD1_k127_5168834_4 Dodecin K09165 - - 0.0000001573 57.0
HKD1_k127_5177356_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1252.0
HKD1_k127_5177356_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001248 261.0
HKD1_k127_5177356_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000004477 227.0
HKD1_k127_5177356_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000001055 82.0
HKD1_k127_5177356_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000002238 65.0
HKD1_k127_5186763_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 2.047e-245 771.0
HKD1_k127_5186763_1 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 3.479e-197 637.0
HKD1_k127_5186763_2 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 435.0
HKD1_k127_5186763_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 316.0
HKD1_k127_5186763_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000002117 221.0
HKD1_k127_5186763_5 C-C_Bond_Lyase of the TIM-Barrel fold K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000008464 207.0
HKD1_k127_5186763_6 CcmE - - - 0.0000000000000000000000000000000000000000000000005035 182.0
HKD1_k127_5186763_7 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0015232,GO:0015886,GO:0022857,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:1901678 3.6.3.41 0.000000000000000000000000000000000000000000000001458 182.0
HKD1_k127_5186763_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.00007671 46.0
HKD1_k127_5187806_0 synthetase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 565.0
HKD1_k127_5187806_1 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 410.0
HKD1_k127_5187806_2 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000007709 218.0
HKD1_k127_5187806_3 - - - - 0.000001174 63.0
HKD1_k127_5188839_0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000002015 214.0
HKD1_k127_5188839_1 - - - - 0.000000000000000000000000000000000000000000000003046 184.0
HKD1_k127_5188839_2 Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016043,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051259,GO:0051260,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070813,GO:0070814,GO:0071840,GO:0097159,GO:1901363,GO:1903136 - 0.000000000000000000000000000000002232 135.0
HKD1_k127_5188839_3 Belongs to the peptidase S1B family - - - 0.000000000000000000000001149 113.0
HKD1_k127_5188839_4 Transposase - - - 0.000000000000000002506 91.0
HKD1_k127_5188839_5 Transposase - - - 0.000000000000001103 79.0
HKD1_k127_5188839_6 Transposase - - - 0.000000000005953 66.0
HKD1_k127_5188839_7 - - - - 0.00000000002381 70.0
HKD1_k127_5195270_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 2.457e-267 831.0
HKD1_k127_5195270_1 FAD dependent oxidoreductase K00316 - 1.5.99.6 1.452e-206 661.0
HKD1_k127_5195270_2 GtrA-like protein K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 550.0
HKD1_k127_5195270_3 Permease family K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 557.0
HKD1_k127_5195270_4 amino acid peptide transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 419.0
HKD1_k127_5195270_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 328.0
HKD1_k127_5195270_6 DoxX - - - 0.00000000000000000000000000000000005429 139.0
HKD1_k127_5195270_7 - - - - 0.00000000000000000001721 105.0
HKD1_k127_5195575_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1637.0
HKD1_k127_5195575_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.877e-262 816.0
HKD1_k127_5195575_10 Domain of unknown function (DUF1820) - - - 0.0000000000000000000000000000000000002366 143.0
HKD1_k127_5195575_11 Type VI secretion K07169,K11894,K11913 - - 0.0000000000000000000000000000000004062 147.0
HKD1_k127_5195575_12 - - - - 0.00000000000000000000007807 106.0
HKD1_k127_5195575_13 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0001503 53.0
HKD1_k127_5195575_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 9.697e-230 721.0
HKD1_k127_5195575_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 444.0
HKD1_k127_5195575_4 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 437.0
HKD1_k127_5195575_5 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 427.0
HKD1_k127_5195575_6 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 379.0
HKD1_k127_5195575_7 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000006926 223.0
HKD1_k127_5195575_8 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) - - - 0.000000000000000000000000000000000000000000000008459 194.0
HKD1_k127_5195575_9 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000001263 151.0
HKD1_k127_5200422_0 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 315.0
HKD1_k127_5200422_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000004735 141.0
HKD1_k127_5200422_2 Transcriptional regulator K07726 - - 0.000000000000000000002888 96.0
HKD1_k127_5200422_3 Transcription factor zinc-finger K09981 - - 0.00000468 54.0
HKD1_k127_5204442_0 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 294.0
HKD1_k127_5204442_1 Hypothetical methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001045 210.0
HKD1_k127_5204442_2 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000001146 126.0
HKD1_k127_5204484_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 589.0
HKD1_k127_5204484_1 COG1077 Actin-like ATPase involved in cell morphogenesis K03569 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 481.0
HKD1_k127_5204484_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 428.0
HKD1_k127_5204484_3 Lytic murein transglycosylase K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 307.0
HKD1_k127_5204484_4 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000003212 232.0
HKD1_k127_5204484_5 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.0000000000000000000000000005556 125.0
HKD1_k127_5204484_6 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000002503 92.0
HKD1_k127_5226148_0 Cys Met metabolism pyridoxal-phosphate-dependent enzyme - - - 4.502e-246 784.0
HKD1_k127_5226148_1 Cytochrome c5530 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 439.0
HKD1_k127_5226148_2 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 436.0
HKD1_k127_5226148_3 Surface antigen K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 419.0
HKD1_k127_5226148_4 Peptidase family S41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 354.0
HKD1_k127_5226148_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.00000000000000000000000000000000002258 138.0
HKD1_k127_5230405_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 5.384e-313 975.0
HKD1_k127_5230405_1 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000004838 241.0
HKD1_k127_5259524_0 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006274 280.0
HKD1_k127_5259524_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000008619 258.0
HKD1_k127_5259524_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0042802,GO:0044424,GO:0044464 6.3.2.45 0.0000000000000000000000000000000004661 141.0
HKD1_k127_5259524_3 - - - - 0.00000000000001696 81.0
HKD1_k127_5259524_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000001529 50.0
HKD1_k127_5282390_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1266.0
HKD1_k127_5282390_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000155 294.0
HKD1_k127_5282390_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000184 263.0
HKD1_k127_5282390_3 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K14160 - - 0.00000000000000000000000000000000000000000000000003383 186.0
HKD1_k127_5282390_4 PFAM Thioredoxin K05838 - - 0.00000000000000000000000000001118 125.0
HKD1_k127_5282872_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01584 - 4.1.1.19 8.554e-279 868.0
HKD1_k127_5282872_1 sulphate transporter - - - 0.00000000000000000000000000000005561 127.0
HKD1_k127_5295696_0 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 427.0
HKD1_k127_5295696_1 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003666 254.0
HKD1_k127_5307331_0 (ABC) transporter K06147,K06148 - - 1.815e-196 633.0
HKD1_k127_5307331_1 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000004246 145.0
HKD1_k127_5316208_0 major facilitator superfamily K03446 - - 2.42e-222 699.0
HKD1_k127_5316208_1 Multidrug resistance efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 406.0
HKD1_k127_5316815_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1230.0
HKD1_k127_5316815_1 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 9.604e-196 626.0
HKD1_k127_5316815_10 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K01488 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 0.000000000000000000000000000000000000000000000000000000000003263 227.0
HKD1_k127_5316815_11 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000001265 207.0
HKD1_k127_5316815_12 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 0.000000000000000000000000000000000000004092 151.0
HKD1_k127_5316815_13 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000002193 162.0
HKD1_k127_5316815_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000008323 142.0
HKD1_k127_5316815_15 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000001234 143.0
HKD1_k127_5316815_16 Phosphate starvation-inducible protein PhoH K06217 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000303 96.0
HKD1_k127_5316815_17 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000001365 82.0
HKD1_k127_5316815_2 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 616.0
HKD1_k127_5316815_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 484.0
HKD1_k127_5316815_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 422.0
HKD1_k127_5316815_5 Protein of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006687 374.0
HKD1_k127_5316815_6 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 320.0
HKD1_k127_5316815_7 PFAM CBS domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 328.0
HKD1_k127_5316815_8 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006748 275.0
HKD1_k127_5316815_9 DNA polymerase III, delta subunit K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000006807 246.0
HKD1_k127_5318827_0 PFAM Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 562.0
HKD1_k127_5318827_1 type IV pilus modification protein PilV K02671 - - 0.000000000000000000000000000000000000000000000000000000000000000245 225.0
HKD1_k127_5318827_2 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000000000000000142 179.0
HKD1_k127_5318827_3 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000000000000000000000001065 136.0
HKD1_k127_5322429_0 Ferrous iron transport protein B C terminus K04759 - - 4.86e-256 803.0
HKD1_k127_5322429_1 ABC transporter K15738 - - 3.146e-197 633.0
HKD1_k127_5322429_10 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000003485 200.0
HKD1_k127_5322429_11 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000005152 168.0
HKD1_k127_5322429_12 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000009651 158.0
HKD1_k127_5322429_13 Lipocalin-like domain - - - 0.00000000000000000000000000000000003648 142.0
HKD1_k127_5322429_14 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000006955 144.0
HKD1_k127_5322429_15 Protease prsW family - - - 0.0000000000000001529 83.0
HKD1_k127_5322429_16 FeoA K04758 - - 0.000000000007733 77.0
HKD1_k127_5322429_17 cytochrome - - - 0.00002136 52.0
HKD1_k127_5322429_18 Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis K08906 - - 0.000607 47.0
HKD1_k127_5322429_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 495.0
HKD1_k127_5322429_3 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 496.0
HKD1_k127_5322429_4 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 459.0
HKD1_k127_5322429_5 4Fe-4S binding domain K08358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 332.0
HKD1_k127_5322429_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 316.0
HKD1_k127_5322429_7 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005288 266.0
HKD1_k127_5322429_8 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001359 246.0
HKD1_k127_5322429_9 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000008724 256.0
HKD1_k127_5326388_0 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 434.0
HKD1_k127_5326388_1 electron transfer flavoprotein beta subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 330.0
HKD1_k127_5326388_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000009987 148.0
HKD1_k127_5326388_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000001313 124.0
HKD1_k127_5340757_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01907 - 6.2.1.16 1.024e-264 829.0
HKD1_k127_5340757_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.375e-227 715.0
HKD1_k127_5340757_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 463.0
HKD1_k127_5340757_3 Reduces the stability of FtsZ polymers in the presence of ATP K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 348.0
HKD1_k127_5340757_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 317.0
HKD1_k127_5340757_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003022 285.0
HKD1_k127_5340757_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000005542 201.0
HKD1_k127_5340757_7 MarR family transcriptional regulator - - - 0.000000000000000000000000000000000001415 150.0
HKD1_k127_5340757_8 glutamate dehydrogenase K15371 - 1.4.1.2 0.00000000000000004674 86.0
HKD1_k127_5340757_9 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0000000002477 63.0
HKD1_k127_53492_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 2.395e-225 708.0
HKD1_k127_53492_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000002221 215.0
HKD1_k127_53492_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000002864 83.0
HKD1_k127_5373292_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.258e-274 871.0
HKD1_k127_5373292_1 Cytochrome c554 and c-prime - - - 3.236e-233 750.0
HKD1_k127_5373292_10 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000003042 187.0
HKD1_k127_5373292_11 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000003533 171.0
HKD1_k127_5373292_12 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000005197 154.0
HKD1_k127_5373292_13 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000003667 137.0
HKD1_k127_5373292_14 YMGG-like Gly-zipper - - - 0.00000000000000000000003668 108.0
HKD1_k127_5373292_15 - - - - 0.000000000002758 75.0
HKD1_k127_5373292_2 protein conserved in bacteria - - - 3.561e-203 651.0
HKD1_k127_5373292_3 pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 8.753e-196 623.0
HKD1_k127_5373292_4 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 587.0
HKD1_k127_5373292_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 531.0
HKD1_k127_5373292_6 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 520.0
HKD1_k127_5373292_7 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 416.0
HKD1_k127_5373292_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K18357 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002835 271.0
HKD1_k127_5373292_9 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000003324 225.0
HKD1_k127_5401463_0 Alpha-amylase domain K01176 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 456.0
HKD1_k127_5401463_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 0.000000000000000000000000000000000000000000000000000000004924 204.0
HKD1_k127_5419866_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 445.0
HKD1_k127_5419866_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 331.0
HKD1_k127_5419866_2 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 298.0
HKD1_k127_5419866_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000001885 271.0
HKD1_k127_5419866_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000001759 236.0
HKD1_k127_5419866_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000001082 220.0
HKD1_k127_5419866_6 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000005764 123.0
HKD1_k127_5419866_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000008414 95.0
HKD1_k127_5458871_0 Malate synthase K01638 - 2.3.3.9 1.081e-238 750.0
HKD1_k127_5458871_1 Catalyzes the reversible formation of glyoxylate and succinate from isocitrate K01637 - 4.1.3.1 1.167e-236 736.0
HKD1_k127_5458871_10 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 285.0
HKD1_k127_5458871_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002549 275.0
HKD1_k127_5458871_12 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.00000000000000000000000000000000000000000000000000000000000000000000004857 252.0
HKD1_k127_5458871_13 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.0000000000000000000000000000000000000000000000000000000000001285 215.0
HKD1_k127_5458871_14 - - - - 0.000000000000000000000000000000000000000000000000297 182.0
HKD1_k127_5458871_15 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity - - - 0.000000000000000000000000000000000000000000188 163.0
HKD1_k127_5458871_16 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000000000000000000000000000000001202 141.0
HKD1_k127_5458871_2 Aldehyde dehydrogenase family K00128 - 1.2.1.3 5.771e-202 663.0
HKD1_k127_5458871_3 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 2.101e-199 629.0
HKD1_k127_5458871_4 Outer membrane receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 626.0
HKD1_k127_5458871_5 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 559.0
HKD1_k127_5458871_6 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 477.0
HKD1_k127_5458871_7 saccharopine dehydrogenase activity K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 443.0
HKD1_k127_5458871_8 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 322.0
HKD1_k127_5458871_9 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 308.0
HKD1_k127_5473787_0 Acetyl-CoA acetyltransferase K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 586.0
HKD1_k127_5473787_1 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 576.0
HKD1_k127_5473787_2 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 418.0
HKD1_k127_5473787_3 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 388.0
HKD1_k127_5473787_4 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 359.0
HKD1_k127_5473787_5 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 324.0
HKD1_k127_5473787_6 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 315.0
HKD1_k127_5473787_7 NAD dependent epimerase/dehydratase family K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 307.0
HKD1_k127_5473787_8 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000007678 185.0
HKD1_k127_5473787_9 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000003817 69.0
HKD1_k127_5543322_0 glutamate synthase K00284 - 1.4.7.1 0.0 2532.0
HKD1_k127_5543322_1 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000002254 211.0
HKD1_k127_554821_0 TonB dependent receptor K02014 - - 3.384e-300 954.0
HKD1_k127_554821_1 trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 555.0
HKD1_k127_554821_2 ATPases associated with a variety of cellular activities K02000 - 3.6.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 437.0
HKD1_k127_554821_3 Binding-protein-dependent transport system inner membrane component K02001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 344.0
HKD1_k127_5560840_0 FAD linked oxidase domain protein K00803,K11472 - 2.5.1.26 1.885e-213 672.0
HKD1_k127_5560840_1 FGGY family of carbohydrate kinases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 589.0
HKD1_k127_5560840_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 467.0
HKD1_k127_5560840_3 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 425.0
HKD1_k127_5560840_4 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K21826 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 302.0
HKD1_k127_5560840_5 Beta-lactamase - - - 0.000000000000000004091 91.0
HKD1_k127_5580999_0 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 415.0
HKD1_k127_5580999_1 Belongs to the heme-copper respiratory oxidase family K02274,K02298 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 353.0
HKD1_k127_5580999_2 oxidase, assembly K02258 - - 0.0000000000000000000000000000000002277 139.0
HKD1_k127_5580999_3 SURF1-like protein K14998 - - 0.00000000000000000000183 99.0
HKD1_k127_5580999_4 Protein of unknown function (DUF2909) - - - 0.00000000001913 69.0
HKD1_k127_5593578_0 Belongs to the GcvT family K00315 - 1.5.8.4 0.0 1018.0
HKD1_k127_5610177_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 570.0
HKD1_k127_5610177_1 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 430.0
HKD1_k127_5610177_2 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000001013 162.0
HKD1_k127_5610177_3 Belongs to the BolA IbaG family - - - 0.000000000000000000005958 94.0
HKD1_k127_5610177_4 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.000003172 57.0
HKD1_k127_5631973_0 Alkyl hydroperoxide reductase K03387 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008785,GO:0009321,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 - 9.913e-203 644.0
HKD1_k127_5631973_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 466.0
HKD1_k127_5631973_2 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 337.0
HKD1_k127_5631973_3 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004281 260.0
HKD1_k127_5631973_4 Inositol monophosphatase family K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.00000000000000000000000000000000000000000000000000000000000003698 229.0
HKD1_k127_5631973_5 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000695 192.0
HKD1_k127_5631973_6 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000001878 174.0
HKD1_k127_5631973_7 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000524 163.0
HKD1_k127_5631973_8 COG2076 Membrane transporters of cations and cationic drugs K03297 - - 0.000000000000000000000000000004502 135.0
HKD1_k127_5631973_9 - - - - 0.00000000000000001104 93.0
HKD1_k127_56454_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2139.0
HKD1_k127_56454_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2126.0
HKD1_k127_56454_10 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002589 149.0
HKD1_k127_56454_11 Haem-degrading - - - 0.00000000002485 71.0
HKD1_k127_56454_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1071.0
HKD1_k127_56454_3 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 368.0
HKD1_k127_56454_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009345 295.0
HKD1_k127_56454_5 PFAM NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002044 252.0
HKD1_k127_56454_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000001509 228.0
HKD1_k127_56454_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000002345 223.0
HKD1_k127_56454_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000003055 218.0
HKD1_k127_56454_9 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000005268 210.0
HKD1_k127_5661056_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000002215 192.0
HKD1_k127_5661056_1 Histidine kinase - - - 0.0000000000000000000000000000000000000005119 166.0
HKD1_k127_5661056_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000001 64.0
HKD1_k127_5687137_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 2.174e-196 619.0
HKD1_k127_5687137_1 Cytochrome C1 family K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007146 261.0
HKD1_k127_5687137_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000003206 248.0
HKD1_k127_5687137_3 Stringent starvation protein A K03599 - - 0.0000000000000000000000000000000000000000000000000000000004136 209.0
HKD1_k127_5687137_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.000000000000000000000000002816 111.0
HKD1_k127_5687137_5 COG2969 Stringent starvation protein B K03600 GO:0000502,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0009376,GO:0009893,GO:0009894,GO:0009896,GO:0010604,GO:0019222,GO:0019899,GO:0031597,GO:0032781,GO:0032991,GO:0042176,GO:0042802,GO:0042803,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045732,GO:0046983,GO:0048518,GO:0050789,GO:0050790,GO:0051117,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:1901363,GO:1902494,GO:1904949,GO:1905368,GO:1905369,GO:1990904 - 0.00000000000000009652 91.0
HKD1_k127_5693499_0 Flavin containing amine oxidoreductase - - - 1.033e-248 777.0
HKD1_k127_5693499_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 396.0
HKD1_k127_5693499_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001486 273.0
HKD1_k127_5693499_3 SnoaL-like domain K06893 - - 0.000000000000001997 78.0
HKD1_k127_5693499_4 - - - - 0.00000000000002497 85.0
HKD1_k127_569876_0 COG2148 Sugar transferases involved in lipopolysaccharide synthesis K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 426.0
HKD1_k127_569876_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000001999 153.0
HKD1_k127_57562_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1107.0
HKD1_k127_57562_1 Global regulator protein family K03563 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005979,GO:0006109,GO:0006139,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010675,GO:0010677,GO:0010906,GO:0010962,GO:0016070,GO:0016071,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032881,GO:0032885,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043255,GO:0043467,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045719,GO:0045912,GO:0045947,GO:0046483,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0062012,GO:0065007,GO:0070873,GO:0070874,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.0000000000002015 70.0
HKD1_k127_5761625_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001509 259.0
HKD1_k127_58457_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 8.938e-211 668.0
HKD1_k127_58457_1 Polymer-forming cytoskeletal - - - 0.00000000000000009053 87.0
HKD1_k127_58457_2 Polymer-forming cytoskeletal - - - 0.000009455 53.0
HKD1_k127_602717_0 YidE YbjL K07085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 369.0
HKD1_k127_602717_1 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000007344 191.0
HKD1_k127_6036750_0 Sulfatase K01130 - 3.1.6.1 1.997e-306 949.0
HKD1_k127_6036750_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004187 246.0
HKD1_k127_6036750_2 - - - - 0.00000000000000000000000000000000000000001887 156.0
HKD1_k127_6036750_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000004512 145.0
HKD1_k127_6043161_0 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 431.0
HKD1_k127_6043161_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 316.0
HKD1_k127_6043161_2 DinB superfamily - - - 0.00000000000003905 77.0
HKD1_k127_6047180_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 6.333e-218 691.0
HKD1_k127_6047180_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 382.0
HKD1_k127_6047180_2 - - - - 0.00000000000000002917 83.0
HKD1_k127_6060182_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 518.0
HKD1_k127_6060182_1 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 304.0
HKD1_k127_6060790_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001125 273.0
HKD1_k127_6060790_1 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000472 202.0
HKD1_k127_6060790_2 Oxidoreductase - - - 0.0000000857 53.0
HKD1_k127_6062554_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 5.055e-202 655.0
HKD1_k127_6069334_0 Belongs to the purine-cytosine permease (2.A.39) family K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 591.0
HKD1_k127_6069334_1 CoA-binding domain protein K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 523.0
HKD1_k127_6069334_2 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 356.0
HKD1_k127_6069334_3 TraB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 315.0
HKD1_k127_6069334_4 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 288.0
HKD1_k127_6069334_5 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000001864 125.0
HKD1_k127_6069334_6 Thioesterase - - - 0.0000000000000000000000000002708 120.0
HKD1_k127_6069334_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000004722 64.0
HKD1_k127_6070335_0 PQQ-like domain K22473 - 1.1.5.5 1.144e-243 773.0
HKD1_k127_6070335_1 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 5.049e-226 711.0
HKD1_k127_6070335_2 Belongs to the GMC oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 610.0
HKD1_k127_6070335_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 380.0
HKD1_k127_6070335_4 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 334.0
HKD1_k127_6070335_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 325.0
HKD1_k127_6070335_6 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000002464 207.0
HKD1_k127_6070335_7 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000002044 206.0
HKD1_k127_6070335_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000001477 188.0
HKD1_k127_6075813_0 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00366,K00381,K00392 GO:0003674,GO:0003824,GO:0004783,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016673,GO:0019419,GO:0020037,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0097159,GO:1901363 1.7.7.1,1.8.1.2,1.8.7.1 7.207e-259 807.0
HKD1_k127_6075813_1 Protein involved in UDP-N-acetylmuramate dehydrogenase activity and amino sugar metabolic process K05797 - 1.17.99.1 3.127e-194 618.0
HKD1_k127_6075813_10 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000001102 194.0
HKD1_k127_6075813_11 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000446 181.0
HKD1_k127_6075813_12 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000003503 106.0
HKD1_k127_6075813_13 Cytochrome c K00406 - - 0.0000000004952 65.0
HKD1_k127_6075813_14 - - - - 0.00000004968 57.0
HKD1_k127_6075813_15 FAD binding domain K02567 - - 0.000008278 48.0
HKD1_k127_6075813_2 Sodium:dicarboxylate symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 598.0
HKD1_k127_6075813_3 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 523.0
HKD1_k127_6075813_4 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 508.0
HKD1_k127_6075813_5 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 514.0
HKD1_k127_6075813_6 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 376.0
HKD1_k127_6075813_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 335.0
HKD1_k127_6075813_8 Belongs to the PAPS reductase family. CysH subfamily K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 325.0
HKD1_k127_6075813_9 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000007367 230.0
HKD1_k127_6081221_0 Protein of unknown function, DUF255 K06888 - - 3.633e-244 772.0
HKD1_k127_6081221_1 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 605.0
HKD1_k127_6081221_10 Protein conserved in bacteria K09922 - - 0.00000000000000000000000000000000000000000000000006038 183.0
HKD1_k127_6081221_11 bis(5'-adenosyl)-triphosphatase activity - - - 0.0000000000000000000000000000000000000000001836 168.0
HKD1_k127_6081221_12 Cysteine-rich motif following a subset of SET domains K07117 - - 0.0000000000000000000000000000000000000000008848 173.0
HKD1_k127_6081221_13 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000001281 147.0
HKD1_k127_6081221_14 Haloacid dehalogenase-like hydrolase K07025,K20866 - 3.1.3.10 0.00000000000000000000000000001379 129.0
HKD1_k127_6081221_2 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009551 548.0
HKD1_k127_6081221_3 (SAM)-dependent K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 456.0
HKD1_k127_6081221_4 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 432.0
HKD1_k127_6081221_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 440.0
HKD1_k127_6081221_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 359.0
HKD1_k127_6081221_7 Belongs to the SUA5 family K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 326.0
HKD1_k127_6081221_8 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001611 282.0
HKD1_k127_6081221_9 Belongs to the ComB family K05979 - 3.1.3.71 0.0000000000000000000000000000000000000000000000000000003594 201.0
HKD1_k127_6081912_0 receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 500.0
HKD1_k127_6081912_1 - - - - 0.00000000000000000000000000000000000008374 145.0
HKD1_k127_6081912_2 acetyltransferase K18815 - 2.3.1.82 0.00000000000000000000000000004806 126.0
HKD1_k127_6081912_3 metal cluster binding K06940,K18475 - - 0.000000000000000000000004646 111.0
HKD1_k127_6081912_4 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000002367 85.0
HKD1_k127_6081912_5 Flavin containing amine oxidoreductase - - - 0.0000000000000006031 91.0
HKD1_k127_6097038_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1618.0
HKD1_k127_6097038_1 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 436.0
HKD1_k127_6097038_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001281 230.0
HKD1_k127_6097038_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000006687 116.0
HKD1_k127_6097038_4 Limonene-1,2-epoxide hydrolase catalytic domain K10533 - 3.3.2.8 0.0000000007474 66.0
HKD1_k127_6101070_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 425.0
HKD1_k127_6101070_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 408.0
HKD1_k127_6101070_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000006459 198.0
HKD1_k127_6101070_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000002467 120.0
HKD1_k127_6101070_4 - - - - 0.000000000004698 79.0
HKD1_k127_6145400_0 Beta-ketoacyl synthase, N-terminal domain - - - 2.678e-213 674.0
HKD1_k127_6145400_1 Belongs to the long-chain O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 508.0
HKD1_k127_6145400_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002006 238.0
HKD1_k127_6147910_0 Radical SAM K01012 - 2.8.1.6 1.192e-210 662.0
HKD1_k127_6147910_1 Radical SAM K09711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 290.0
HKD1_k127_6152865_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 3554.0
HKD1_k127_6152865_1 Glutathione S-transferase K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 472.0
HKD1_k127_6152865_10 transporter component K07112 - - 0.00000000000000000000000000000001027 135.0
HKD1_k127_6152865_11 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000008182 120.0
HKD1_k127_6152865_12 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000008966 114.0
HKD1_k127_6152865_13 cytochrome C peroxidase - - - 0.000000000000000001487 99.0
HKD1_k127_6152865_14 cytochrome C peroxidase - - - 0.00000000001934 68.0
HKD1_k127_6152865_15 SnoaL-like domain - - - 0.0004802 52.0
HKD1_k127_6152865_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009553 416.0
HKD1_k127_6152865_3 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 374.0
HKD1_k127_6152865_4 Luciferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 361.0
HKD1_k127_6152865_5 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000385 249.0
HKD1_k127_6152865_6 Virulence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002873 241.0
HKD1_k127_6152865_7 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000001646 155.0
HKD1_k127_6152865_8 transporter component K07112 - - 0.000000000000000000000000000000000005906 142.0
HKD1_k127_6152865_9 Protein of unknown function (DUF2799) - - - 0.000000000000000000000000000000005902 136.0
HKD1_k127_6156243_0 Domain of unknown function (DUF4032) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 415.0
HKD1_k127_6156243_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001991 263.0
HKD1_k127_6156478_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.856e-205 657.0
HKD1_k127_6156478_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 402.0
HKD1_k127_6156478_2 Rubrerythrin - - - 0.0000000000000000000000000000000000001067 160.0
HKD1_k127_6156478_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000001486 104.0
HKD1_k127_6156804_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 8.881e-290 902.0
HKD1_k127_6156804_1 PQQ-dependent polyvinyl alcohol dehydrogenase - - - 4.931e-210 670.0
HKD1_k127_6156804_2 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 396.0
HKD1_k127_6156804_3 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 347.0
HKD1_k127_6156804_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000002607 234.0
HKD1_k127_6156804_5 proline dipeptidase activity - - - 0.000000000000000007155 97.0
HKD1_k127_6156804_6 RHS Repeat - - - 0.00000101 62.0
HKD1_k127_6158392_0 CHASE2 domain protein - - - 9.763e-215 679.0
HKD1_k127_6179060_0 silver ion transport K07787 - - 0.0 1360.0
HKD1_k127_6179060_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000003655 228.0
HKD1_k127_6179060_2 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000001381 170.0
HKD1_k127_6181681_0 Acetylornithine deacetylase Succinyl-diaminopimelate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 577.0
HKD1_k127_6181681_1 Uncharacterized protein conserved in bacteria (DUF2058) K09912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000005079 150.0
HKD1_k127_6181681_2 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000003022 124.0
HKD1_k127_6181681_3 protease with the C-terminal PDZ domain - - - 0.000000000000000000004341 95.0
HKD1_k127_6182165_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 3.316e-207 667.0
HKD1_k127_6182165_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 346.0
HKD1_k127_6182165_2 PFAM Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000355 215.0
HKD1_k127_6182165_3 Domain of unknown function (DUF1841) - - - 0.0000000000000000000000000000000000000000000001223 171.0
HKD1_k127_6182165_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000005486 76.0
HKD1_k127_6191021_0 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1052.0
HKD1_k127_6191021_1 sarcosine oxidase, beta subunit K00303 - 1.5.3.1 1.085e-224 704.0
HKD1_k127_6191863_0 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 548.0
HKD1_k127_6191863_1 Phosphate transport regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 557.0
HKD1_k127_6191863_2 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 369.0
HKD1_k127_6200342_0 AAA-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 509.0
HKD1_k127_6200342_1 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 477.0
HKD1_k127_6200342_2 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 452.0
HKD1_k127_6200342_3 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 417.0
HKD1_k127_6200342_4 TIGRFAM sulfate ABC transporter, permease protein CysW, sulfate ABC transporter, permease protein K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 385.0
HKD1_k127_6200342_5 Sulfate ABC transporter, permease protein CysT K02046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 342.0
HKD1_k127_6200342_6 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001284 261.0
HKD1_k127_6200342_7 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002957 251.0
HKD1_k127_6200342_8 ABC-type multidrug transport system ATPase and permease K06147 - - 0.00000000000000000000000000000000000000000000000000000000000009365 214.0
HKD1_k127_620315_0 Belongs to the 5'-nucleotidase family K01081,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 485.0
HKD1_k127_620315_1 PFAM Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 471.0
HKD1_k127_620315_2 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000004903 203.0
HKD1_k127_620315_3 PFAM alpha beta hydrolase fold K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000002022 207.0
HKD1_k127_620315_4 - - - - 0.0000000000000000000000000004164 121.0
HKD1_k127_6213523_0 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 377.0
HKD1_k127_6213523_1 Unextendable partial coding region - - - 0.000000000000000000002426 94.0
HKD1_k127_6213523_2 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000007232 85.0
HKD1_k127_6213523_3 - - - - 0.000000001268 64.0
HKD1_k127_6218594_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 1571.0
HKD1_k127_6218594_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 4.433e-262 813.0
HKD1_k127_6218594_10 Asparaginase K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 324.0
HKD1_k127_6218594_11 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 317.0
HKD1_k127_6218594_12 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002051 272.0
HKD1_k127_6218594_13 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000135 240.0
HKD1_k127_6218594_14 Universal stress protein family K14055 - - 0.0000000000000000000000000000000000000000000000000000000000004579 222.0
HKD1_k127_6218594_15 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000002074 214.0
HKD1_k127_6218594_16 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000271 199.0
HKD1_k127_6218594_17 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000001876 168.0
HKD1_k127_6218594_18 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000216 133.0
HKD1_k127_6218594_19 Protein-glutamate methylesterase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000003256 107.0
HKD1_k127_6218594_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 1.516e-212 687.0
HKD1_k127_6218594_20 MerR HTH family regulatory protein K18997 - - 0.000000000000000007118 87.0
HKD1_k127_6218594_21 HlyD family secretion protein K01993 - - 0.0000000000001755 76.0
HKD1_k127_6218594_22 Cytochrome oxidase maturation protein - - - 0.0000000000004198 72.0
HKD1_k127_6218594_23 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.0000000000004905 70.0
HKD1_k127_6218594_24 - - - - 0.000000000001727 72.0
HKD1_k127_6218594_25 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.000000001551 61.0
HKD1_k127_6218594_26 FixH K09926 - - 0.000000006902 59.0
HKD1_k127_6218594_3 TIGRFAM cytochrome c oxidase accessory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 586.0
HKD1_k127_6218594_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 502.0
HKD1_k127_6218594_5 GGDEF domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 475.0
HKD1_k127_6218594_6 DnaJ-class molecular chaperone K05516 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 389.0
HKD1_k127_6218594_7 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 384.0
HKD1_k127_6218594_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 360.0
HKD1_k127_6218594_9 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 342.0
HKD1_k127_6221873_0 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.0 1088.0
HKD1_k127_6221873_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 601.0
HKD1_k127_6221873_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K17735 - 1.1.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 516.0
HKD1_k127_6221873_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 495.0
HKD1_k127_6221873_4 Serine aminopeptidase, S33 K09023 - - 0.0000000000000000000000000000000000000000000000000000006913 209.0
HKD1_k127_6221873_5 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.0000000001483 63.0
HKD1_k127_6229540_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 2.068e-205 644.0
HKD1_k127_6229540_1 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 4.711e-198 636.0
HKD1_k127_6229540_2 TIGRFAM acyltransferase, WS DGAT MGAT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 554.0
HKD1_k127_6229540_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007265 544.0
HKD1_k127_6229540_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003541 285.0
HKD1_k127_6229540_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002648 266.0
HKD1_k127_6229540_6 QueF-like protein K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000005348 263.0
HKD1_k127_6229540_7 Belongs to the long-chain O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000002087 185.0
HKD1_k127_6229540_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000823 150.0
HKD1_k127_6255053_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1335.0
HKD1_k127_6255053_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 3.088e-203 647.0
HKD1_k127_6255053_2 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 385.0
HKD1_k127_6255053_3 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 304.0
HKD1_k127_6255053_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000002761 192.0
HKD1_k127_6259954_0 5-oxoprolinase K01469 - 3.5.2.9 0.0 1132.0
HKD1_k127_6259954_1 SMART Peptidoglycan-binding Lysin subgroup K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 358.0
HKD1_k127_6259954_2 Phage tail sheath C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 326.0
HKD1_k127_6259954_3 TPM domain - - - 0.0000000000000000000000000000000000001575 144.0
HKD1_k127_6264260_0 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 449.0
HKD1_k127_6264260_1 NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 309.0
HKD1_k127_6264260_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000003513 188.0
HKD1_k127_6264260_3 Putative aminopeptidase - - - 0.000000000000005662 77.0
HKD1_k127_6281018_0 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 406.0
HKD1_k127_6281018_1 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000000006773 184.0
HKD1_k127_6281018_2 COG0350 Methylated DNA-protein cysteine methyltransferase K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000001519 185.0
HKD1_k127_6281018_3 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000006566 157.0
HKD1_k127_6281018_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000001069 86.0
HKD1_k127_6289536_0 Belongs to the GARS family K01945,K13713 GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 538.0
HKD1_k127_6289536_1 Bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 411.0
HKD1_k127_6289536_2 glycosyl transferase family - - - 0.0000000000000000000000000000000000000003256 165.0
HKD1_k127_6317419_0 Succinyldiaminopimelate K14261,K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 526.0
HKD1_k127_6317419_1 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 428.0
HKD1_k127_6317419_2 Belongs to the transferase hexapeptide repeat family K00674 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 411.0
HKD1_k127_6317419_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 387.0
HKD1_k127_6317419_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000003652 165.0
HKD1_k127_6317419_5 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 0.000000000000001256 78.0
HKD1_k127_6318319_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1158.0
HKD1_k127_6318319_1 Amidohydrolase family - - - 3.853e-195 619.0
HKD1_k127_6318319_10 Thioesterase superfamily K19222 - 3.1.2.28 0.000000000000000000000000000000000000000000000000000007798 195.0
HKD1_k127_6318319_11 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000009479 182.0
HKD1_k127_6318319_12 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000225 125.0
HKD1_k127_6318319_13 OmpA-like transmembrane domain - - - 0.00000000000000000000003824 108.0
HKD1_k127_6318319_14 OmpA-like transmembrane domain - - - 0.000000000000000000001441 101.0
HKD1_k127_6318319_2 COG1960 Acyl-CoA dehydrogenases K20035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 617.0
HKD1_k127_6318319_3 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 319.0
HKD1_k127_6318319_4 fumarylacetoacetate hydrolase K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 308.0
HKD1_k127_6318319_5 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 308.0
HKD1_k127_6318319_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003735 263.0
HKD1_k127_6318319_7 maleylacetoacetate isomerase K01801 - 5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001845 263.0
HKD1_k127_6318319_8 PFAM cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000003558 209.0
HKD1_k127_6318319_9 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000001593 207.0
HKD1_k127_6328423_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 2.65e-267 836.0
HKD1_k127_6328423_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 7.882e-259 818.0
HKD1_k127_6328423_2 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001872 248.0
HKD1_k127_6328423_3 gluconolactonase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000001534 180.0
HKD1_k127_6328423_4 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000009454 88.0
HKD1_k127_6328423_5 Cupin domain - - - 0.0000000000000000002264 88.0
HKD1_k127_6338060_0 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 347.0
HKD1_k127_6364082_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.079e-316 994.0
HKD1_k127_6364082_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0003952,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 8.498e-307 954.0
HKD1_k127_6364082_10 protein conserved in bacteria K09793 - - 0.00000000000000000000000000000000000001005 148.0
HKD1_k127_6364082_11 - - - - 0.0000000000000002545 83.0
HKD1_k127_6364082_2 Pyruvate formate lyase-activating protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 595.0
HKD1_k127_6364082_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 491.0
HKD1_k127_6364082_4 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 368.0
HKD1_k127_6364082_5 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 324.0
HKD1_k127_6364082_6 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008886 271.0
HKD1_k127_6364082_7 PFAM histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000000000168 184.0
HKD1_k127_6364082_8 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000001138 175.0
HKD1_k127_6364082_9 AMMECR1 - - - 0.000000000000000000000000000000000000002933 153.0
HKD1_k127_6370339_0 Lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 317.0
HKD1_k127_6370339_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000003283 265.0
HKD1_k127_6370339_2 Belongs to the ATCase OTCase family K09065,K13043 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 0.000000000000000000000000000000000000002295 153.0
HKD1_k127_6370339_3 EamA-like transporter family K08978 - - 0.0000000000000000005959 87.0
HKD1_k127_6371173_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.292e-306 951.0
HKD1_k127_6371173_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 2.509e-201 629.0
HKD1_k127_6371173_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 528.0
HKD1_k127_6371173_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 519.0
HKD1_k127_6371173_4 ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 292.0
HKD1_k127_6371173_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000915 205.0
HKD1_k127_6377298_0 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 5.037e-220 691.0
HKD1_k127_6377298_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000001563 263.0
HKD1_k127_6377298_2 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000001019 226.0
HKD1_k127_6407491_0 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 447.0
HKD1_k127_6407491_1 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 322.0
HKD1_k127_6407491_2 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 317.0
HKD1_k127_6407491_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000003119 221.0
HKD1_k127_6407491_4 COG3103 SH3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000003802 216.0
HKD1_k127_6407491_5 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000719 180.0
HKD1_k127_6407491_6 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000001227 104.0
HKD1_k127_6407491_7 Domain of unknown function (DUF4266) - - - 0.000000000000000001753 94.0
HKD1_k127_6416980_0 PFAM PrkA AAA K07180 - - 7.021e-300 934.0
HKD1_k127_6416980_1 SpoVR family K06415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 529.0
HKD1_k127_6416980_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 410.0
HKD1_k127_6416980_3 Belongs to the UPF0229 family K09786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 391.0
HKD1_k127_6416980_4 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 370.0
HKD1_k127_6416980_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000001156 201.0
HKD1_k127_6416980_6 CHASE2 domain protein - - - 0.000000000000000000000000003705 114.0
HKD1_k127_645287_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 479.0
HKD1_k127_645287_1 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 363.0
HKD1_k127_645287_10 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712 - - 0.000000000000000000004576 94.0
HKD1_k127_645287_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 322.0
HKD1_k127_645287_3 COG4942 Membrane-bound metallopeptidase - GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000004154 241.0
HKD1_k127_645287_4 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000001177 211.0
HKD1_k127_645287_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000006243 200.0
HKD1_k127_645287_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000004072 158.0
HKD1_k127_645287_7 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000003485 123.0
HKD1_k127_645287_8 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000372 120.0
HKD1_k127_645287_9 PFAM Rhodanese-like K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000002869 108.0
HKD1_k127_648210_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 8.242e-271 844.0
HKD1_k127_648210_1 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000001784 231.0
HKD1_k127_648210_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000001023 129.0
HKD1_k127_648210_3 Regulatory protein, FmdB family - - - 0.00000000000000001838 85.0
HKD1_k127_6546326_0 lytic transglycosylase K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 405.0
HKD1_k127_6546326_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 357.0
HKD1_k127_6546326_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005189 284.0
HKD1_k127_6546326_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000001279 207.0
HKD1_k127_6551236_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 5.903e-271 861.0
HKD1_k127_6551236_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 409.0
HKD1_k127_6551236_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000001716 132.0
HKD1_k127_6560867_0 Binding-protein-dependent transport systems inner membrane component K02050 - - 2.985e-229 722.0
HKD1_k127_6560867_1 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 602.0
HKD1_k127_6560867_2 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 395.0
HKD1_k127_6560867_3 S-acyltransferase activity K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 375.0
HKD1_k127_6560867_5 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001627 243.0
HKD1_k127_6560867_6 transporter - - - 0.0000000000000000001914 89.0
HKD1_k127_6595602_0 DNA segregation ATPase FtsK SpoIIIE K03466 - - 1.683e-288 904.0
HKD1_k127_6595602_1 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 1.174e-197 622.0
HKD1_k127_6595602_2 ATPase (AAA K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 569.0
HKD1_k127_6595602_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 497.0
HKD1_k127_6595602_4 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 359.0
HKD1_k127_6595602_5 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001276 272.0
HKD1_k127_6595602_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000005277 181.0
HKD1_k127_6595602_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000004672 134.0
HKD1_k127_6666062_0 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 482.0
HKD1_k127_6666062_1 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 355.0
HKD1_k127_6666062_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000001922 65.0
HKD1_k127_6666062_2 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 338.0
HKD1_k127_6666062_3 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 297.0
HKD1_k127_6666062_4 Part of the ABC transporter FtsEX involved in cellular division K09811 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008614 270.0
HKD1_k127_6666062_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004586 265.0
HKD1_k127_6666062_6 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001483 243.0
HKD1_k127_6666062_7 periplasmic protein K09797 - - 0.0000000000000000000000000000000000000000000004005 176.0
HKD1_k127_6666062_8 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000005784 102.0
HKD1_k127_6666062_9 BON domain - - - 0.000000000000003714 80.0
HKD1_k127_6687614_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1483.0
HKD1_k127_6687614_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 4.716e-223 706.0
HKD1_k127_6687614_10 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 299.0
HKD1_k127_6687614_11 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 293.0
HKD1_k127_6687614_12 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 299.0
HKD1_k127_6687614_13 KR domain K05296 - 1.1.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009677 274.0
HKD1_k127_6687614_14 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000004388 237.0
HKD1_k127_6687614_15 Glycosyltransferase, group 2 family protein - - - 0.000000000000000000000000000000000000000000000000000000000001039 228.0
HKD1_k127_6687614_16 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000002417 179.0
HKD1_k127_6687614_17 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000003965 160.0
HKD1_k127_6687614_18 Choline/ethanolamine kinase - - - 0.00000000000000000000000001538 121.0
HKD1_k127_6687614_19 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000004887 110.0
HKD1_k127_6687614_2 Ring hydroxylating alpha subunit (catalytic domain) - - - 9.643e-211 664.0
HKD1_k127_6687614_20 nicotinamide mononucleotide transporter K03811 - - 0.000000000000000000001914 96.0
HKD1_k127_6687614_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008803 560.0
HKD1_k127_6687614_4 Transketolase, C-terminal domain K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 471.0
HKD1_k127_6687614_5 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 444.0
HKD1_k127_6687614_6 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 438.0
HKD1_k127_6687614_7 Dehydrogenase E1 component K21416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 414.0
HKD1_k127_6687614_8 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 372.0
HKD1_k127_6687614_9 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 335.0
HKD1_k127_6712069_0 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 479.0
HKD1_k127_6712069_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 483.0
HKD1_k127_6712069_10 EamA-like transporter family - - - 0.00000000000000000000000000000000000000002483 158.0
HKD1_k127_6712069_11 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000004341 150.0
HKD1_k127_6712069_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 472.0
HKD1_k127_6712069_3 Histidine kinase K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 445.0
HKD1_k127_6712069_4 Peptidogalycan biosysnthesis/recognition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 424.0
HKD1_k127_6712069_5 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 421.0
HKD1_k127_6712069_6 Esterase lipase K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000994 408.0
HKD1_k127_6712069_7 abc transporter atp-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 342.0
HKD1_k127_6712069_8 Secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008636 259.0
HKD1_k127_6712069_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000001415 184.0
HKD1_k127_67125_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0 1039.0
HKD1_k127_67125_1 PFAM Pyridoxal-dependent decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 565.0
HKD1_k127_67125_10 Transcriptional regulator K18900 - - 0.00000000000000000000000000000000000000000000000000000000000001163 227.0
HKD1_k127_67125_11 membrane K15977 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000001591 161.0
HKD1_k127_67125_12 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000001505 121.0
HKD1_k127_67125_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04127,K11325,K21174 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 468.0
HKD1_k127_67125_3 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 420.0
HKD1_k127_67125_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 411.0
HKD1_k127_67125_5 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 401.0
HKD1_k127_67125_6 histidine kinase HAMP region domain protein K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 341.0
HKD1_k127_67125_7 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 332.0
HKD1_k127_67125_8 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity - - - 0.00000000000000000000000000000000000000000000000000000000000000006019 229.0
HKD1_k127_67125_9 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000001068 222.0
HKD1_k127_67322_0 Exporters of the RND superfamily K07003 - - 0.0 1082.0
HKD1_k127_67322_1 peptidase K01354 - 3.4.21.83 1.766e-218 692.0
HKD1_k127_67322_10 - - - - 0.0000000000000001184 92.0
HKD1_k127_67322_2 Protein of unknown function (DUF1329) - - - 6.309e-210 660.0
HKD1_k127_67322_3 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 603.0
HKD1_k127_67322_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 437.0
HKD1_k127_67322_5 Glutathione S-transferase, C-terminal domain K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 356.0
HKD1_k127_67322_6 COG0501 Zn-dependent protease with chaperone function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 330.0
HKD1_k127_67322_7 DSBA-like thioredoxin domain K14584 - 5.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 310.0
HKD1_k127_67322_8 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 302.0
HKD1_k127_67589_0 Serine dehydratase beta chain K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 377.0
HKD1_k127_67589_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000282 251.0
HKD1_k127_67589_2 PFAM Phosphoglycerate mutase K08296 - - 0.0000000000000000000000000000000000005066 148.0
HKD1_k127_67589_3 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.000000000000000000000001768 103.0
HKD1_k127_6808166_0 Major Facilitator Superfamily K02445,K07783 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 342.0
HKD1_k127_6808166_1 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 308.0
HKD1_k127_6908684_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.7e-320 1002.0
HKD1_k127_6908684_1 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 606.0
HKD1_k127_6908684_10 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000118 271.0
HKD1_k127_6908684_11 PFAM Peptidoglycan-binding lysin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001108 255.0
HKD1_k127_6908684_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000003085 231.0
HKD1_k127_6908684_13 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000003117 168.0
HKD1_k127_6908684_14 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000000004773 168.0
HKD1_k127_6908684_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000001655 143.0
HKD1_k127_6908684_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000005874 117.0
HKD1_k127_6908684_17 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000277 115.0
HKD1_k127_6908684_18 AntiSigma factor - - - 0.0000000000000223 83.0
HKD1_k127_6908684_19 Domain of unknown function (DUF4136) - - - 0.000004248 56.0
HKD1_k127_6908684_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 531.0
HKD1_k127_6908684_3 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 491.0
HKD1_k127_6908684_4 response regulator receiver K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 438.0
HKD1_k127_6908684_5 serine protease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 411.0
HKD1_k127_6908684_6 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 376.0
HKD1_k127_6908684_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008548 358.0
HKD1_k127_6908684_8 PFAM DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 329.0
HKD1_k127_6908684_9 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 290.0
HKD1_k127_7044026_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 364.0
HKD1_k127_7044026_1 Mur ligase middle domain protein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000001331 261.0
HKD1_k127_7044026_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000006514 213.0
HKD1_k127_7044026_3 - - - - 0.00000002587 64.0
HKD1_k127_7044026_4 Acetyltransferase (GNAT) domain - - - 0.00000189 59.0
HKD1_k127_7046518_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 5.33e-218 685.0
HKD1_k127_7046518_1 3-oxoadipate enol-lactonase K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000004978 268.0
HKD1_k127_7046518_2 Domain of unknown function (DUF4286) - - - 0.00000000000000000000002563 109.0
HKD1_k127_7046518_3 Protein of unknown function (DUF3667) - - - 0.000000000000000000001021 104.0
HKD1_k127_7046518_4 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.000000000000000000001394 96.0
HKD1_k127_7046582_0 RES - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003711 273.0
HKD1_k127_7046582_1 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000009854 158.0
HKD1_k127_7046582_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00004127 47.0
HKD1_k127_7048144_0 TIGRFAM RHS repeat-associated core domain-containing protein, YD repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 413.0
HKD1_k127_7048144_1 RHS repeat-associated core domain protein - - - 0.000000000000000000000000003279 130.0
HKD1_k127_7064035_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 3.193e-256 797.0
HKD1_k127_7064035_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 579.0
HKD1_k127_7064035_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 366.0
HKD1_k127_7064035_3 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000001271 223.0
HKD1_k127_7064035_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000008787 160.0
HKD1_k127_7064035_5 competence protein ComEA K02237 - - 0.000000000000001005 82.0
HKD1_k127_7066192_0 PFAM Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 586.0
HKD1_k127_7066192_1 Phospholipase D. Active site motifs. K06132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 534.0
HKD1_k127_7066192_2 (barnase) inhibitor - - - 0.000000000000000000000000005466 117.0
HKD1_k127_7066192_3 Guanyl-specific ribonuclease Sa - - - 0.00000000000000000003846 89.0
HKD1_k127_7066192_4 6-phosphogluconolactonase activity K20276 - - 0.0000181 55.0
HKD1_k127_7069859_0 Carboxyl transferase domain K13778 - 6.4.1.5 5.211e-254 807.0
HKD1_k127_7069859_1 Biotin carboxylase C-terminal domain K01968,K13777 - 6.4.1.4,6.4.1.5 1.069e-245 779.0
HKD1_k127_7069859_2 acyl-CoA dehydrogenase K11731 - - 5.775e-194 610.0
HKD1_k127_7069859_3 Enoyl-(Acyl carrier protein) reductase K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 407.0
HKD1_k127_7069859_4 Enoyl-CoA hydratase/isomerase K13779 - 4.2.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000005177 247.0
HKD1_k127_7069859_5 Pfam:Kce - - - 0.00000000000000000000000001337 122.0
HKD1_k127_7075401_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 450.0
HKD1_k127_7075401_1 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000002524 265.0
HKD1_k127_7075401_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000002323 252.0
HKD1_k127_7075401_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000007736 244.0
HKD1_k127_7075401_4 lipid-A-disaccharide synthase activity - - - 0.00000000000000000000000000000002206 134.0
HKD1_k127_7075401_5 Belongs to the UPF0434 family K09791 - - 0.000000000000000000000682 96.0
HKD1_k127_7075872_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 393.0
HKD1_k127_7075872_1 Chromate resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 377.0
HKD1_k127_7075872_2 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 349.0
HKD1_k127_7075872_3 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009803 276.0
HKD1_k127_7075872_4 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001047 260.0
HKD1_k127_7075872_5 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000003747 206.0
HKD1_k127_7075872_6 - - - - 0.000000000000000000000000146 121.0
HKD1_k127_7075872_7 - - - - 0.000001094 59.0
HKD1_k127_7075883_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 557.0
HKD1_k127_7075883_1 Anthranilate synthase component I K01657,K01665 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 436.0
HKD1_k127_7075883_10 General secretion pathway protein J K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0000000000000000000006319 107.0
HKD1_k127_7075883_11 Type II secretion system (T2SS), protein I - - - 0.000000000000000002088 94.0
HKD1_k127_7075883_12 general secretion pathway protein h K02457 - - 0.00000000001473 74.0
HKD1_k127_7075883_2 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 375.0
HKD1_k127_7075883_3 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 339.0
HKD1_k127_7075883_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 334.0
HKD1_k127_7075883_5 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000003091 198.0
HKD1_k127_7075883_6 Amino-transferase class IV K02619 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 4.1.3.38 0.00000000000000000000000000000000000000000000000000002354 202.0
HKD1_k127_7075883_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000003992 188.0
HKD1_k127_7075883_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000001891 127.0
HKD1_k127_7075883_9 Rhomboid family - - - 0.000000000000000000000000000009509 126.0
HKD1_k127_7075944_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 374.0
HKD1_k127_7075944_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009025 284.0
HKD1_k127_7075944_2 PFAM Phosphatidic acid phosphatase type 2 haloperoxidase - - - 0.000000000000000000000000000000000000000000000000000000003254 215.0
HKD1_k127_7075944_3 Fad dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000002488 178.0
HKD1_k127_7075944_4 Water Stress and Hypersensitive response - - - 0.0000000000000000000000000000000000000000000003868 171.0
HKD1_k127_7075944_5 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564 - 0.000000000000000000000000000001079 126.0
HKD1_k127_7078419_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 7.078e-312 968.0
HKD1_k127_7078419_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 491.0
HKD1_k127_7078419_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 448.0
HKD1_k127_7078419_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004161 248.0
HKD1_k127_7078419_4 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000008449 245.0
HKD1_k127_7078625_0 TIGRFAM FeS assembly protein SufB K09014 - - 1.86e-269 840.0
HKD1_k127_7078625_1 SMART Nucleotide binding protein, PINc K07175 - - 2.314e-214 676.0
HKD1_k127_7078625_10 assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001696 261.0
HKD1_k127_7078625_11 VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000003687 215.0
HKD1_k127_7078625_12 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000005908 199.0
HKD1_k127_7078625_13 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000002874 202.0
HKD1_k127_7078625_14 Peroxiredoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000005044 200.0
HKD1_k127_7078625_15 PFAM Amino acid-binding ACT K03567 - - 0.0000000000000000000000000000000000000000000000000002666 196.0
HKD1_k127_7078625_16 ABC-type transport system involved in resistance to organic solvents auxiliary component K07323 - - 0.000000000000000000000000000000000000009367 160.0
HKD1_k127_7078625_17 MlaD protein K02067 - - 0.00000000000000000000000000000000002335 152.0
HKD1_k127_7078625_18 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000009142 138.0
HKD1_k127_7078625_19 transcriptional regulator - - - 0.000000000000000000000000000000009664 134.0
HKD1_k127_7078625_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 566.0
HKD1_k127_7078625_20 Rieske-like [2Fe-2S] domain K05710,K18087 - - 0.0000000000000000000005841 100.0
HKD1_k127_7078625_21 Phosphoglycerate mutase family - - - 0.000000000000009979 83.0
HKD1_k127_7078625_22 NTP binding protein (Contains STAS domain) K07122 - - 0.0000000008937 66.0
HKD1_k127_7078625_23 Recombinase zinc beta ribbon domain - - - 0.00000697 56.0
HKD1_k127_7078625_3 FeS assembly ATPase SufC K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 392.0
HKD1_k127_7078625_4 PFAM ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 346.0
HKD1_k127_7078625_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 343.0
HKD1_k127_7078625_6 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 314.0
HKD1_k127_7078625_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000001429 270.0
HKD1_k127_7078625_8 FeS assembly SUF system protein SufT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002497 257.0
HKD1_k127_7078625_9 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001009 259.0
HKD1_k127_7079865_0 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 428.0
HKD1_k127_7079865_2 Belongs to the peptidase S8 family K20276 - - 0.0000001468 61.0
HKD1_k127_7081432_0 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 408.0
HKD1_k127_7081432_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000005984 208.0
HKD1_k127_7081432_2 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.0000000000000000000000000000000000000000000000000004288 190.0
HKD1_k127_7092307_0 Phosphoribulokinase / Uridine kinase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 446.0
HKD1_k127_7092307_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 451.0
HKD1_k127_7092307_2 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 413.0
HKD1_k127_7092307_3 CbbX protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 414.0
HKD1_k127_7092307_4 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 286.0
HKD1_k127_7092307_5 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000001193 208.0
HKD1_k127_7093289_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 2.149e-207 658.0
HKD1_k127_7093289_1 protein conserved in bacteria K16514 GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016853,GO:0016860,GO:0016863,GO:0017144,GO:0018918,GO:0018958,GO:0019336,GO:0019396,GO:0019439,GO:0019752,GO:0032787,GO:0042537,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 5.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 471.0
HKD1_k127_7093289_2 Aldolase/RraA K02553,K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 321.0
HKD1_k127_7093289_3 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K04099 - 1.13.11.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001427 273.0
HKD1_k127_7093289_4 Dehydrogenase - - - 0.00000000000000000000000000006622 126.0
HKD1_k127_7108152_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 7.462e-307 949.0
HKD1_k127_7108152_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 434.0
HKD1_k127_7108152_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000008222 151.0
HKD1_k127_7108152_3 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000005579 134.0
HKD1_k127_7108152_4 TonB-dependent receptor - - - 0.0004005 46.0
HKD1_k127_7126556_0 iron-nicotianamine transmembrane transporter activity - - - 1.911e-310 970.0
HKD1_k127_7126556_1 M3B, thimet oligopeptidase F K01392 - 3.4.24.15 6.917e-262 823.0
HKD1_k127_7126556_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 8.409e-236 743.0
HKD1_k127_7126556_3 Glutathione S-Transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009671 278.0
HKD1_k127_7126556_4 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003313 279.0
HKD1_k127_7126556_5 IQR COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002226 267.0
HKD1_k127_7126556_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000003768 235.0
HKD1_k127_7126556_7 carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000388 125.0
HKD1_k127_7126556_8 - - - - 0.000000005123 65.0
HKD1_k127_7127681_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1095.0
HKD1_k127_7127681_1 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 9.735e-259 808.0
HKD1_k127_7127681_10 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000007362 247.0
HKD1_k127_7127681_11 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000009029 219.0
HKD1_k127_7127681_12 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000000001717 127.0
HKD1_k127_7127681_13 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000004075 91.0
HKD1_k127_7127681_14 - - - - 0.0000000000001476 73.0
HKD1_k127_7127681_15 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000002413 72.0
HKD1_k127_7127681_17 peptidase M24 - - - 0.0001078 46.0
HKD1_k127_7127681_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 5.447e-207 653.0
HKD1_k127_7127681_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 488.0
HKD1_k127_7127681_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 471.0
HKD1_k127_7127681_5 mechanosensitive ion channel K03442,K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 422.0
HKD1_k127_7127681_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 402.0
HKD1_k127_7127681_7 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000073 277.0
HKD1_k127_7127681_8 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000005564 262.0
HKD1_k127_7127681_9 cytochrome c oxidase (Subunit II) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003556 254.0
HKD1_k127_7132265_0 DNA polymerase X family K02347 - - 2.848e-221 700.0
HKD1_k127_7132265_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 602.0
HKD1_k127_7132265_2 trimethylamine methyltransferase K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 469.0
HKD1_k127_7132265_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009254 431.0
HKD1_k127_7132265_4 Domain of unknown function (DUF4382) - - - 0.0000000000000000000000000000000000000000000000000000001657 208.0
HKD1_k127_7132265_5 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.0000000000000000000000000000000000000000000000000004192 190.0
HKD1_k127_7132265_7 Aminotransferase K03430 - 2.6.1.37 0.0000000004356 64.0
HKD1_k127_7134088_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1048.0
HKD1_k127_7134088_1 - - - - 3.81e-203 653.0
HKD1_k127_7134088_2 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 8.579e-201 640.0
HKD1_k127_7134088_3 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 514.0
HKD1_k127_7134088_4 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 409.0
HKD1_k127_7134088_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 348.0
HKD1_k127_7134088_6 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 335.0
HKD1_k127_7134088_7 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000001614 130.0
HKD1_k127_7136897_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 8.543e-226 737.0
HKD1_k127_7136897_1 COG3156 Type II secretory pathway, component PulK K02460 - - 0.000000000000000000000000000000000000000000000000001223 198.0
HKD1_k127_7136897_2 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.000000000000000000000000000000002224 145.0
HKD1_k127_7136897_3 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.0000000000000000000000288 113.0
HKD1_k127_7136897_4 General secretion pathway protein J K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.00000000002922 67.0
HKD1_k127_7136897_5 Type II secretion system (T2SS), protein N K02463 - - 0.0001071 53.0
HKD1_k127_7164586_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.606e-201 643.0
HKD1_k127_7164586_1 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 618.0
HKD1_k127_7164586_10 PFAM Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001716 249.0
HKD1_k127_7164586_11 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000001221 216.0
HKD1_k127_7164586_12 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000005715 175.0
HKD1_k127_7164586_2 With LivFGHM is involved in the high affinity leucine transport K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 584.0
HKD1_k127_7164586_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009619 535.0
HKD1_k127_7164586_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 443.0
HKD1_k127_7164586_5 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 441.0
HKD1_k127_7164586_6 ABC transporter K01996,K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 321.0
HKD1_k127_7164586_7 Mur ligase middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 330.0
HKD1_k127_7164586_8 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 310.0
HKD1_k127_7164586_9 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009956 278.0
HKD1_k127_7191183_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 324.0
HKD1_k127_7191183_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001632 271.0
HKD1_k127_7191183_10 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000002048 146.0
HKD1_k127_7191183_11 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000008855 124.0
HKD1_k127_7191183_12 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000003433 108.0
HKD1_k127_7191183_13 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000003263 104.0
HKD1_k127_7191183_14 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000001765 76.0
HKD1_k127_7191183_2 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000002956 216.0
HKD1_k127_7191183_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000003354 223.0
HKD1_k127_7191183_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003776 213.0
HKD1_k127_7191183_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000003516 198.0
HKD1_k127_7191183_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001179 183.0
HKD1_k127_7191183_7 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000001262 167.0
HKD1_k127_7191183_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000006443 164.0
HKD1_k127_7191183_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000008044 154.0
HKD1_k127_7226212_0 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 399.0
HKD1_k127_7226212_1 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000367 198.0
HKD1_k127_7226212_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000006364 190.0
HKD1_k127_7226212_3 - - - - 0.00002097 54.0
HKD1_k127_7241013_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 0.0 1158.0
HKD1_k127_7241013_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 4.679e-244 790.0
HKD1_k127_7241013_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 6.881e-225 717.0
HKD1_k127_7241013_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 316.0
HKD1_k127_7241013_4 Protein of unknown function (DUF1249) K09920 - - 0.00000000000000000000000000000001936 132.0
HKD1_k127_7247345_0 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005124 250.0
HKD1_k127_7247345_1 M COG4775 Outer membrane protein protective antigen OMA87 K07278 - - 0.0000000000000000000000000000000000000000000000000000000003156 222.0
HKD1_k127_7247345_2 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000004253 172.0
HKD1_k127_7251402_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000009595 212.0
HKD1_k127_7264443_0 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 607.0
HKD1_k127_7264443_1 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 444.0
HKD1_k127_7264443_2 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 428.0
HKD1_k127_7264443_3 dehydrogenase e1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 419.0
HKD1_k127_7264443_4 Transketolase, pyrimidine binding domain K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 415.0
HKD1_k127_7264443_5 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000007272 87.0
HKD1_k127_7274095_0 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 315.0
HKD1_k127_7274095_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K09699 - 2.3.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 297.0
HKD1_k127_7290690_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 499.0
HKD1_k127_7290690_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 425.0
HKD1_k127_7290690_2 Type II secretory pathway, component HofQ K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 362.0
HKD1_k127_7290690_3 PFAM Ig domain protein, group 1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 321.0
HKD1_k127_7290690_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000001483 199.0
HKD1_k127_7290690_5 sister chromatid segregation - - - 0.00000001712 61.0
HKD1_k127_7300987_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 340.0
HKD1_k127_7300987_1 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 316.0
HKD1_k127_7300987_2 ThiS family K03636 - - 0.000000000000000007596 94.0
HKD1_k127_7308513_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 7.815e-227 714.0
HKD1_k127_7308513_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000001077 237.0
HKD1_k127_7314032_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 391.0
HKD1_k127_7314032_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 332.0
HKD1_k127_7314032_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000005449 246.0
HKD1_k127_7314032_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000008459 160.0
HKD1_k127_7315325_0 Hydrogenase formation hypA family K04654 GO:0003674,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0036211,GO:0042165,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070025,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 572.0
HKD1_k127_7315325_1 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 332.0
HKD1_k127_7315325_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000004558 188.0
HKD1_k127_7315325_3 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000000001627 166.0
HKD1_k127_7315325_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000799 145.0
HKD1_k127_7315325_5 - - - - 0.000000000000000000000000000000001645 132.0
HKD1_k127_7315325_6 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000009215 117.0
HKD1_k127_7315325_7 - - - - 0.0000000184 60.0
HKD1_k127_7319348_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 7.282e-286 883.0
HKD1_k127_7334507_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 7.101e-296 929.0
HKD1_k127_7334507_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002452 241.0
HKD1_k127_7334507_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000006936 199.0
HKD1_k127_7360630_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 349.0
HKD1_k127_7360630_1 Purine nucleoside permease - - - 0.00000000000000000000000000000000000000000000001034 182.0
HKD1_k127_7373942_0 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000000000000000000000000000000000000000002165 211.0
HKD1_k127_7373942_2 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000001315 164.0
HKD1_k127_7380003_0 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000004174 142.0
HKD1_k127_7395452_0 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 394.0
HKD1_k127_7395452_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 305.0
HKD1_k127_7395452_2 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001382 254.0
HKD1_k127_7395452_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006033 267.0
HKD1_k127_7395452_4 Flavodoxin domain K00230 GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.3 0.0000000000000000000000000000000000000000000000000006192 192.0
HKD1_k127_7395452_5 Protein of unknown function (DUF3187) - - - 0.00000000000000000000000000000000000000000000002953 190.0
HKD1_k127_7395452_6 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000001633 144.0
HKD1_k127_7395452_7 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000105 134.0
HKD1_k127_7395452_8 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000003507 72.0
HKD1_k127_7395452_9 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000007043 57.0
HKD1_k127_741464_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1437.0
HKD1_k127_741464_1 Translation Elongation Factor K03833 - - 1.119e-204 670.0
HKD1_k127_741464_2 Formate dehydrogenase N, transmembrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 519.0
HKD1_k127_741464_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 503.0
HKD1_k127_741464_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 345.0
HKD1_k127_741464_5 Formate dehydrogenase gamma subunit K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002952 271.0
HKD1_k127_741464_6 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006919 274.0
HKD1_k127_741464_7 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007052 269.0
HKD1_k127_7428059_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 599.0
HKD1_k127_7428059_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 475.0
HKD1_k127_7428059_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 340.0
HKD1_k127_7428059_3 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000002963 140.0
HKD1_k127_7428059_4 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000003275 102.0
HKD1_k127_7428059_5 transcriptional regulator - - - 0.00000000004635 69.0
HKD1_k127_7428059_6 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00004127 47.0
HKD1_k127_7473796_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 339.0
HKD1_k127_7473796_1 Capsular polysaccharide biosynthesis protein CapK K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000003285 196.0
HKD1_k127_7473796_2 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) - - - 0.000000000000000000000000000000002345 145.0
HKD1_k127_7498460_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.282e-197 616.0
HKD1_k127_7498460_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 554.0
HKD1_k127_7498460_2 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 430.0
HKD1_k127_7498460_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 395.0
HKD1_k127_7498460_4 YdjC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002647 275.0
HKD1_k127_7498460_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008997 280.0
HKD1_k127_7498460_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000004468 204.0
HKD1_k127_7498460_7 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000004503 179.0
HKD1_k127_7498460_8 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000001303 165.0
HKD1_k127_7498460_9 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000003191 143.0
HKD1_k127_7512184_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.48e-294 921.0
HKD1_k127_7512184_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 1.065e-195 622.0
HKD1_k127_7512184_2 PFAM TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 551.0
HKD1_k127_7512184_3 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009278 552.0
HKD1_k127_7512184_4 protein conserved in bacteria - - - 0.0000000000002022 75.0
HKD1_k127_7513530_0 Acetolactate synthase K01652 - 2.2.1.6 7.176e-296 918.0
HKD1_k127_7513530_1 alcohol dehydrogenase K00001,K00055 - 1.1.1.1,1.1.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 503.0
HKD1_k127_7513530_10 Ferredoxin K02230 - 6.6.1.2 0.000000000000000000000000000000003131 133.0
HKD1_k127_7513530_2 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 424.0
HKD1_k127_7513530_3 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008256 405.0
HKD1_k127_7513530_4 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 338.0
HKD1_k127_7513530_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001417 282.0
HKD1_k127_7513530_6 Glutathione S-transferase, C-terminal domain K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000001775 249.0
HKD1_k127_7513530_7 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000006358 189.0
HKD1_k127_7513530_8 Belongs to the P(II) protein family K04752 GO:0003674,GO:0005488,GO:0005515,GO:0006808,GO:0008150,GO:0042802,GO:0045848,GO:0048518,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000004759 181.0
HKD1_k127_7513530_9 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000002689 161.0
HKD1_k127_7535501_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 425.0
HKD1_k127_7535501_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 410.0
HKD1_k127_7535501_2 surface antigen variable number repeat protein K07001 - - 0.000000000000000000000000000000000000000000000000006906 199.0
HKD1_k127_7613765_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.289e-286 895.0
HKD1_k127_7613765_1 Glycine cleavage T-protein C-terminal barrel domain - - - 3.368e-194 611.0
HKD1_k127_7613765_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 569.0
HKD1_k127_7613765_3 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 336.0
HKD1_k127_7613765_4 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 333.0
HKD1_k127_7613765_5 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 312.0
HKD1_k127_7613765_6 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000007533 230.0
HKD1_k127_7722282_0 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 341.0
HKD1_k127_77950_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 297.0
HKD1_k127_7887718_0 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease K03694 - - 2.184e-206 651.0
HKD1_k127_7887718_1 PFAM Type II secretion system protein E K02454 - - 8.434e-203 646.0
HKD1_k127_7887718_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 578.0
HKD1_k127_7887718_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 563.0
HKD1_k127_7887718_4 General Secretion Pathway protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 573.0
HKD1_k127_7887718_5 General secretion pathway protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 419.0
HKD1_k127_7887718_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000002229 160.0
HKD1_k127_7887718_7 Type II secretion system protein C - - - 0.00000000000000000000000000000000000192 151.0
HKD1_k127_7887718_8 Belongs to the HSP15 family K04762 - - 0.000000000000000000000000000001644 125.0
HKD1_k127_7887718_9 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000001094 94.0
HKD1_k127_7936316_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00244 - 1.3.5.4 2.5e-323 1002.0
HKD1_k127_7936316_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.724e-227 713.0
HKD1_k127_7936316_10 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000004526 242.0
HKD1_k127_7936316_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000173 220.0
HKD1_k127_7936316_12 Cytochrome c - - - 0.000000000000000000000000000000000000000000000002911 179.0
HKD1_k127_7936316_13 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000000000000002094 170.0
HKD1_k127_7936316_14 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000001305 138.0
HKD1_k127_7936316_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 9.208e-213 676.0
HKD1_k127_7936316_3 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 592.0
HKD1_k127_7936316_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 501.0
HKD1_k127_7936316_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 451.0
HKD1_k127_7936316_6 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 376.0
HKD1_k127_7936316_7 fumarate reductase respiratory complex transmembrane subunit K00246 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 317.0
HKD1_k127_7936316_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 310.0
HKD1_k127_7936316_9 NADH:flavin oxidoreductase / NADH oxidase family K00219,K09461 - 1.14.13.40,1.3.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000002321 246.0
HKD1_k127_85282_0 Repeat of Unknown Function (DUF347) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 354.0
HKD1_k127_85282_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003436 270.0
HKD1_k127_85282_2 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000004491 229.0
HKD1_k127_85282_3 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.00000000000000000000000000000000000006687 145.0
HKD1_k127_85282_4 PFAM translation initiation factor SUI1 K03113 - - 0.0000000000000000000000000000000009417 139.0
HKD1_k127_85282_5 glutathione s-transferase K00799 - 2.5.1.18 0.0000000294 56.0
HKD1_k127_8544_0 Sulfatase K01130 - 3.1.6.1 0.0 1313.0
HKD1_k127_8544_1 - - - - 0.00000000000000000000000000000000000000000000000002185 188.0
HKD1_k127_8544_2 Radical SAM superfamily K06871 - - 0.000000000000000000000000000000000006597 138.0
HKD1_k127_927073_0 COG2133 Glucose sorbosone dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 429.0
HKD1_k127_927073_1 glutathione s-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 286.0
HKD1_k127_927073_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000008054 177.0
HKD1_k127_97105_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1264.0
HKD1_k127_97448_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 3.448e-245 764.0
HKD1_k127_97448_1 Glycine cleavage system P-protein K00282 - 1.4.4.2 1.214e-199 631.0
HKD1_k127_97448_2 serine-type endopeptidase activity - GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006508,GO:0006629,GO:0006807,GO:0006915,GO:0006950,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009416,GO:0009507,GO:0009536,GO:0009628,GO:0009642,GO:0009644,GO:0009892,GO:0009987,GO:0010109,GO:0010205,GO:0012501,GO:0016787,GO:0017171,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0033554,GO:0034605,GO:0042548,GO:0043155,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043467,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051603,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1905156 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 581.0
HKD1_k127_97448_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 490.0
HKD1_k127_97448_4 pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 442.0
HKD1_k127_97448_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.0000000000000000000000000000000000000000000006476 175.0