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Overview

ID MAG01704
Name HKD1_bin.15
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Myxococcota_A
Class UBA9160
Order UBA9160
Family UBA9160
Genus JAWOLJ01
Species
Assembly information
Completeness (%) 92.79
Contamination (%) 2.33
GC content (%) 72.0
N50 (bp) 23,100
Genome size (bp) 3,997,617

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3469

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1006_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.819e-218 685.0
HKD1_k127_1006_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 579.0
HKD1_k127_1006_10 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000001252 85.0
HKD1_k127_1006_11 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000004516 64.0
HKD1_k127_1006_12 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.000000438 63.0
HKD1_k127_1006_13 chitin binding K21712 - - 0.0008059 53.0
HKD1_k127_1006_2 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 520.0
HKD1_k127_1006_3 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 414.0
HKD1_k127_1006_4 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 302.0
HKD1_k127_1006_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000005462 254.0
HKD1_k127_1006_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000001605 207.0
HKD1_k127_1006_7 PFAM phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000199 129.0
HKD1_k127_1006_8 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000002341 121.0
HKD1_k127_1006_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000189 96.0
HKD1_k127_100664_0 Phosphoglucose isomerase K01810 - 5.3.1.9 7.256e-283 902.0
HKD1_k127_100664_1 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 514.0
HKD1_k127_100664_2 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 509.0
HKD1_k127_100664_3 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 370.0
HKD1_k127_100664_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 343.0
HKD1_k127_100664_5 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000007485 264.0
HKD1_k127_100664_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000002334 178.0
HKD1_k127_1025458_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 504.0
HKD1_k127_1025458_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000001237 159.0
HKD1_k127_1025458_2 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ - - - 0.000000000000000000000001984 113.0
HKD1_k127_1025458_3 - - - - 0.0000001642 59.0
HKD1_k127_1025458_4 Putative zinc-finger - - - 0.00001657 55.0
HKD1_k127_1039166_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 605.0
HKD1_k127_1039166_1 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 471.0
HKD1_k127_1039166_10 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000007666 125.0
HKD1_k127_1039166_11 Tetratricopeptide repeat - - - 0.000000000000000001756 101.0
HKD1_k127_1039166_12 - - - - 0.00000000000001044 81.0
HKD1_k127_1039166_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.00000319 57.0
HKD1_k127_1039166_2 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 410.0
HKD1_k127_1039166_3 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 406.0
HKD1_k127_1039166_4 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005698 282.0
HKD1_k127_1039166_5 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001522 269.0
HKD1_k127_1039166_6 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000159 247.0
HKD1_k127_1039166_7 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000002657 178.0
HKD1_k127_1039166_8 methyltransferase - - - 0.00000000000000000000000000000000000000992 158.0
HKD1_k127_1039166_9 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000001017 141.0
HKD1_k127_1042371_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 520.0
HKD1_k127_1042371_1 formyl-CoA transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 481.0
HKD1_k127_1042371_2 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 418.0
HKD1_k127_1042371_3 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000003173 208.0
HKD1_k127_1042371_4 Acetone carboxylase gamma K10856 - 6.4.1.6 0.0000000000000000000000000000000000000000000000000001774 197.0
HKD1_k127_1057224_0 Phospholipid methyltransferase - - - 0.000000000000000000002635 105.0
HKD1_k127_1057224_1 serine threonine protein kinase - - - 0.00000000000000000001498 105.0
HKD1_k127_1057224_2 Sigma-70 region 2 K03088 - - 0.00000000000000027 89.0
HKD1_k127_1057224_3 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.0000000000000129 82.0
HKD1_k127_1058410_0 Heat shock 70 kDa protein K04043 - - 7.69e-198 642.0
HKD1_k127_1058410_1 PAS domain K13598 - 2.7.13.3 2.678e-196 643.0
HKD1_k127_1058410_10 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000001146 244.0
HKD1_k127_1058410_11 PFAM Protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000009152 247.0
HKD1_k127_1058410_12 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000003748 209.0
HKD1_k127_1058410_13 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000000000000000008542 199.0
HKD1_k127_1058410_14 repeat protein - - - 0.00000000000000000000000000000000000000000000000000175 213.0
HKD1_k127_1058410_15 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000001977 183.0
HKD1_k127_1058410_16 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000001936 150.0
HKD1_k127_1058410_17 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000009515 118.0
HKD1_k127_1058410_18 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000181 111.0
HKD1_k127_1058410_19 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000001988 126.0
HKD1_k127_1058410_2 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 580.0
HKD1_k127_1058410_20 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000001796 100.0
HKD1_k127_1058410_21 Cytochrome c554 and c-prime - - - 0.00000000000000000002485 108.0
HKD1_k127_1058410_22 Cytochrome c554 and c-prime - - - 0.00000000000000000005679 107.0
HKD1_k127_1058410_23 6-phosphogluconolactonase activity - - - 0.0000000000002486 85.0
HKD1_k127_1058410_24 PilZ domain - - - 0.000000437 59.0
HKD1_k127_1058410_25 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.00000106 63.0
HKD1_k127_1058410_3 response regulator K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 552.0
HKD1_k127_1058410_4 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 453.0
HKD1_k127_1058410_5 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 380.0
HKD1_k127_1058410_6 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 329.0
HKD1_k127_1058410_7 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 310.0
HKD1_k127_1058410_8 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 306.0
HKD1_k127_1058410_9 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004272 282.0
HKD1_k127_1075332_0 Acyclic terpene utilisation family protein AtuA - - - 5.726e-285 887.0
HKD1_k127_1075332_1 carboxylase K01968 - 6.4.1.4 1.238e-269 859.0
HKD1_k127_1075332_10 Enoyl-CoA hydratase K01692,K13766 - 4.2.1.17,4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000003591 238.0
HKD1_k127_1075332_11 COG0604 NADPH quinone reductase and related Zn-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000004083 236.0
HKD1_k127_1075332_12 Glyoxalase-like domain K07032 - - 0.0000000000000000000000000000000000000000000000000000000000000003021 222.0
HKD1_k127_1075332_13 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000003718 234.0
HKD1_k127_1075332_14 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000008686 186.0
HKD1_k127_1075332_15 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000009971 165.0
HKD1_k127_1075332_16 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000001835 128.0
HKD1_k127_1075332_17 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000004252 119.0
HKD1_k127_1075332_18 - - - - 0.000002599 50.0
HKD1_k127_1075332_2 Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 603.0
HKD1_k127_1075332_3 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 409.0
HKD1_k127_1075332_4 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 318.0
HKD1_k127_1075332_5 cytochrome p450 K21033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 317.0
HKD1_k127_1075332_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003608 288.0
HKD1_k127_1075332_7 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002538 286.0
HKD1_k127_1075332_8 PFAM 2-nitropropane dioxygenase NPD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005849 282.0
HKD1_k127_1075332_9 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002542 263.0
HKD1_k127_108285_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 1.143e-227 724.0
HKD1_k127_108285_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 375.0
HKD1_k127_108285_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000002966 158.0
HKD1_k127_108285_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000009099 98.0
HKD1_k127_1085888_0 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 559.0
HKD1_k127_1085888_1 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 525.0
HKD1_k127_1085888_10 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000007011 87.0
HKD1_k127_1085888_11 Von Willebrand factor A domain-containing protein 7-like - - - 0.000002422 58.0
HKD1_k127_1085888_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 482.0
HKD1_k127_1085888_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 372.0
HKD1_k127_1085888_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000001955 260.0
HKD1_k127_1085888_5 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000002709 163.0
HKD1_k127_1085888_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000002741 164.0
HKD1_k127_1085888_7 phosphoglycerate mutase family - - - 0.0000000000000000000000000000004221 132.0
HKD1_k127_1085888_8 PFAM Cyclic nucleotide-binding K10914 - - 0.0000000000000000007471 98.0
HKD1_k127_1085888_9 VanZ like family - - - 0.000000000000004661 81.0
HKD1_k127_1144744_0 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000001951 185.0
HKD1_k127_1144744_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000009112 194.0
HKD1_k127_1144744_2 Fibronectin type 3 domain K01179,K06882 - 3.2.1.4 0.00000000000000000000000000000000000000000001136 181.0
HKD1_k127_1144744_3 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000003934 148.0
HKD1_k127_1144744_4 CAAX protease self-immunity K07052 - - 0.00000000001313 74.0
HKD1_k127_1179082_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 3.746e-245 777.0
HKD1_k127_1179082_1 oligoendopeptidase F K08602 - - 2.79e-198 645.0
HKD1_k127_1179082_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 344.0
HKD1_k127_1179082_3 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001857 207.0
HKD1_k127_1179082_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000000000000000000000000000000000000008144 193.0
HKD1_k127_1179082_5 protoporphyrinogen oxidase activity K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000001839 154.0
HKD1_k127_1179082_6 Serine aminopeptidase, S33 - - - 0.0000000000000000007318 101.0
HKD1_k127_1179082_7 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000005857 75.0
HKD1_k127_1205680_0 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 622.0
HKD1_k127_1205680_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 597.0
HKD1_k127_1205680_10 acetylesterase activity K01066 - - 0.00000000000000000000000000000000000000000000000000004471 195.0
HKD1_k127_1205680_11 Carotenoid biosynthesis protein K22502 - 5.5.1.19 0.0000000000000000000000000000000000000000000000000001009 197.0
HKD1_k127_1205680_12 PFAM Alpha beta hydrolase fold-3 domain protein K01066 - - 0.0000000000000000000000000000000000000000003131 161.0
HKD1_k127_1205680_13 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000003792 158.0
HKD1_k127_1205680_15 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000007123 128.0
HKD1_k127_1205680_16 MAATS-type transcriptional repressor, C-terminal region K03577 - - 0.00000000005539 74.0
HKD1_k127_1205680_17 phosphorylase K01243 - 3.2.2.9 0.000000003322 70.0
HKD1_k127_1205680_18 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000001712 62.0
HKD1_k127_1205680_19 Sh3 type 3 domain protein - - - 0.000001846 60.0
HKD1_k127_1205680_2 Squalene-hopene cyclase C-terminal domain K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 488.0
HKD1_k127_1205680_3 Belongs to the long-chain O-acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 441.0
HKD1_k127_1205680_4 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 409.0
HKD1_k127_1205680_5 Domain of unknown function (DUF3463) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 379.0
HKD1_k127_1205680_6 phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 357.0
HKD1_k127_1205680_7 KR domain K00076 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008709,GO:0009056,GO:0009987,GO:0016043,GO:0016054,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0030573,GO:0032787,GO:0033764,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901360,GO:1901575,GO:1901615 1.1.1.159 0.000000000000000000000000000000000000000000000000000000000000000000000000000006228 275.0
HKD1_k127_1205680_8 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000001259 213.0
HKD1_k127_1205680_9 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000005121 211.0
HKD1_k127_1214498_0 Fumarate reductase flavoprotein C-term - - - 9.625e-218 691.0
HKD1_k127_1214498_1 Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 310.0
HKD1_k127_1214498_2 MAPEG family - - - 0.000000000000000000000000001665 119.0
HKD1_k127_1214498_3 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00247 GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008177,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016627,GO:0016635,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803 - 0.0000000001292 74.0
HKD1_k127_1214498_4 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00246 - - 0.000003951 54.0
HKD1_k127_1273657_0 conserved protein (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 366.0
HKD1_k127_1273657_1 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000131 174.0
HKD1_k127_1273657_2 EXOIII K02342 - 2.7.7.7 0.0000000000000000000000000000439 134.0
HKD1_k127_1287979_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006543 244.0
HKD1_k127_1287979_1 Tetratricopeptide repeats - - - 0.0000000000000000000000000002206 131.0
HKD1_k127_1335800_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 381.0
HKD1_k127_1335800_1 carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 317.0
HKD1_k127_1335800_10 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000005923 158.0
HKD1_k127_1335800_11 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 GO:0003674,GO:0003824,GO:0004068,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.11 0.000000000000000000000000000000000000002605 162.0
HKD1_k127_1335800_12 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000123 135.0
HKD1_k127_1335800_13 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000001179 122.0
HKD1_k127_1335800_14 catechol 2,3-dioxygenase activity K07104 - 1.13.11.2 0.0000000000000000000002997 101.0
HKD1_k127_1335800_15 Cytochrome c K12263 - - 0.00000000000000002158 87.0
HKD1_k127_1335800_16 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000452 81.0
HKD1_k127_1335800_17 acyl-CoA dehydrogenase - - - 0.0000000000006031 71.0
HKD1_k127_1335800_18 TonB C terminal - - - 0.0000000001969 72.0
HKD1_k127_1335800_19 F420H(2)-dependent quinone reductase - - - 0.0000001431 60.0
HKD1_k127_1335800_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 315.0
HKD1_k127_1335800_3 TIGRFAM Na H antiporter, bacterial form K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 310.0
HKD1_k127_1335800_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 310.0
HKD1_k127_1335800_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001289 282.0
HKD1_k127_1335800_6 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000006396 270.0
HKD1_k127_1335800_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000001002 209.0
HKD1_k127_1335800_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000001501 192.0
HKD1_k127_1335800_9 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000005431 182.0
HKD1_k127_136394_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 644.0
HKD1_k127_136394_1 Belongs to the GPAT DAPAT family K00631 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 597.0
HKD1_k127_136394_10 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000001747 269.0
HKD1_k127_136394_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000001973 240.0
HKD1_k127_136394_12 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000005027 205.0
HKD1_k127_136394_13 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000002264 203.0
HKD1_k127_136394_14 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000002987 186.0
HKD1_k127_136394_15 Nitrile hydratase beta subunit - - - 0.000000000000000000000000971 108.0
HKD1_k127_136394_16 SMP-30/Gluconolaconase/LRE-like region - - - 0.0000000000000000000005414 103.0
HKD1_k127_136394_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000828 102.0
HKD1_k127_136394_18 Universal stress protein family - - - 0.00000000000000005736 87.0
HKD1_k127_136394_19 Haem-degrading K11477 - - 0.0000000000001284 74.0
HKD1_k127_136394_2 acetyl-CoA hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 522.0
HKD1_k127_136394_3 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 488.0
HKD1_k127_136394_4 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 480.0
HKD1_k127_136394_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 395.0
HKD1_k127_136394_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 421.0
HKD1_k127_136394_7 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 385.0
HKD1_k127_136394_8 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 375.0
HKD1_k127_136394_9 PFAM Nitrile hydratase alpha K01721 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009794 278.0
HKD1_k127_137587_0 oligopeptide transporter, OPT family - - - 2.089e-197 638.0
HKD1_k127_137587_1 acyl-CoA dehydrogenase K14448 - 1.3.8.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 413.0
HKD1_k127_137587_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 362.0
HKD1_k127_137587_3 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001619 266.0
HKD1_k127_137587_4 D-isomer specific 2-hydroxyacid dehydrogenase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001211 249.0
HKD1_k127_137587_5 UPF0056 inner membrane protein K05595 - - 0.0000000000000000000000000000000000000000000008992 176.0
HKD1_k127_137587_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000001723 149.0
HKD1_k127_1470032_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1028.0
HKD1_k127_1470032_1 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 8.931e-219 687.0
HKD1_k127_1470032_10 Cysteine synthase K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 504.0
HKD1_k127_1470032_11 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 451.0
HKD1_k127_1470032_12 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 455.0
HKD1_k127_1470032_13 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 437.0
HKD1_k127_1470032_14 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 409.0
HKD1_k127_1470032_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 427.0
HKD1_k127_1470032_16 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 427.0
HKD1_k127_1470032_17 Nitronate monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 408.0
HKD1_k127_1470032_18 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 383.0
HKD1_k127_1470032_19 Cellulase (glycosyl hydrolase family 5) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 376.0
HKD1_k127_1470032_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18687 - 6.2.1.41 7.437e-210 664.0
HKD1_k127_1470032_20 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 372.0
HKD1_k127_1470032_21 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 375.0
HKD1_k127_1470032_22 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 359.0
HKD1_k127_1470032_23 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 335.0
HKD1_k127_1470032_24 KR domain K00059 GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 346.0
HKD1_k127_1470032_25 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 340.0
HKD1_k127_1470032_26 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 342.0
HKD1_k127_1470032_27 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 322.0
HKD1_k127_1470032_28 lipid-transfer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 321.0
HKD1_k127_1470032_29 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 332.0
HKD1_k127_1470032_3 Thiolase, C-terminal domain K00626,K00632 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575 2.3.1.16,2.3.1.9 6.353e-200 627.0
HKD1_k127_1470032_30 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 325.0
HKD1_k127_1470032_31 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 305.0
HKD1_k127_1470032_32 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 291.0
HKD1_k127_1470032_33 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001607 286.0
HKD1_k127_1470032_34 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000313 267.0
HKD1_k127_1470032_35 Acyl dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005181 240.0
HKD1_k127_1470032_36 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008861 241.0
HKD1_k127_1470032_37 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000002743 226.0
HKD1_k127_1470032_38 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000006641 209.0
HKD1_k127_1470032_39 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000001933 214.0
HKD1_k127_1470032_4 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 617.0
HKD1_k127_1470032_40 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000001203 196.0
HKD1_k127_1470032_41 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000003599 176.0
HKD1_k127_1470032_42 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.0000000000000000000000000000000000000000000105 181.0
HKD1_k127_1470032_43 long-chain fatty acid transporting porin activity K07267 - - 0.0000000000000000000000000000000000000000009668 172.0
HKD1_k127_1470032_44 XdhC and CoxI family - - - 0.0000000000000000000000000000000000000001269 157.0
HKD1_k127_1470032_45 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000000000000393 153.0
HKD1_k127_1470032_46 Alpha/beta hydrolase family K18092 - - 0.0000000000000000000000000000000001954 139.0
HKD1_k127_1470032_47 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000000000000000000005188 111.0
HKD1_k127_1470032_48 - - - - 0.000000000000000000000002079 117.0
HKD1_k127_1470032_49 Transcriptional regulator - - - 0.0000000000000000007661 103.0
HKD1_k127_1470032_5 Acyl-CoA dehydrogenase, middle domain K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 603.0
HKD1_k127_1470032_50 regulation of endocannabinoid signaling pathway - - - 0.000000000002988 70.0
HKD1_k127_1470032_52 DGC domain - - - 0.0000004909 56.0
HKD1_k127_1470032_53 phosphate ion binding K02040 - - 0.000002728 58.0
HKD1_k127_1470032_54 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00009106 46.0
HKD1_k127_1470032_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 602.0
HKD1_k127_1470032_7 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 554.0
HKD1_k127_1470032_8 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 575.0
HKD1_k127_1470032_9 acetyl-coa acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 523.0
HKD1_k127_1571251_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 3.658e-261 824.0
HKD1_k127_1571251_1 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 531.0
HKD1_k127_1571251_10 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000001107 130.0
HKD1_k127_1571251_11 Domain of unknown function (DUF1956) - - - 0.000000000000000000000000005953 126.0
HKD1_k127_1571251_12 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.0000000000000000000000003787 121.0
HKD1_k127_1571251_13 OmpA MotB domain protein K02557 - - 0.00000001551 63.0
HKD1_k127_1571251_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 406.0
HKD1_k127_1571251_3 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006899 276.0
HKD1_k127_1571251_4 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000001546 243.0
HKD1_k127_1571251_5 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000001564 209.0
HKD1_k127_1571251_6 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000003872 192.0
HKD1_k127_1571251_7 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000002153 205.0
HKD1_k127_1571251_8 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000005831 196.0
HKD1_k127_1571251_9 dioxygenase K11159 - - 0.00000000000000000000000000000008711 126.0
HKD1_k127_1605419_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1196.0
HKD1_k127_1605419_1 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 541.0
HKD1_k127_1605419_10 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000001427 267.0
HKD1_k127_1605419_11 of the major facilitator superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000001898 245.0
HKD1_k127_1605419_12 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000131 212.0
HKD1_k127_1605419_13 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000003876 212.0
HKD1_k127_1605419_14 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.00000000000000000000000000000000000000000000000000000003546 202.0
HKD1_k127_1605419_15 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000001915 211.0
HKD1_k127_1605419_16 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 GO:0000041,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006826,GO:0008150,GO:0008152,GO:0008823,GO:0015677,GO:0015682,GO:0016020,GO:0016021,GO:0016491,GO:0016722,GO:0016723,GO:0030001,GO:0031224,GO:0031226,GO:0033216,GO:0034220,GO:0034755,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0052851,GO:0055085,GO:0055114,GO:0071944,GO:0072512,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098706,GO:0098711,GO:0098739,GO:0099587 1.5.1.40 0.0000000000000000000000000000000000000000001932 175.0
HKD1_k127_1605419_17 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000002042 175.0
HKD1_k127_1605419_18 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000003049 172.0
HKD1_k127_1605419_19 lipoprotein biosynthetic process K13292 - - 0.000000000000000000000000000000000000001727 168.0
HKD1_k127_1605419_2 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 477.0
HKD1_k127_1605419_20 4Fe-4S binding domain - - - 0.00000000000000000000000000000000001392 137.0
HKD1_k127_1605419_21 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000596 143.0
HKD1_k127_1605419_22 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000000000001484 132.0
HKD1_k127_1605419_23 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000001365 129.0
HKD1_k127_1605419_24 PilZ domain K02676 - - 0.00000000000000000000007509 104.0
HKD1_k127_1605419_25 - - - - 0.000000000000000000001961 106.0
HKD1_k127_1605419_26 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000004391 98.0
HKD1_k127_1605419_27 Ndr family - - - 0.000000000000003999 82.0
HKD1_k127_1605419_28 PFAM Lytic transglycosylase catalytic - - - 0.000000000006883 75.0
HKD1_k127_1605419_29 transcriptional regulator K09017 - - 0.0000000009167 71.0
HKD1_k127_1605419_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 425.0
HKD1_k127_1605419_30 long-chain fatty acid transporting porin activity - - - 0.000000003148 69.0
HKD1_k127_1605419_31 - - - - 0.0000179 53.0
HKD1_k127_1605419_32 AntiSigma factor - - - 0.0001064 55.0
HKD1_k127_1605419_33 Inositol monophosphatase K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.0001423 54.0
HKD1_k127_1605419_34 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.0007529 49.0
HKD1_k127_1605419_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 383.0
HKD1_k127_1605419_5 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 372.0
HKD1_k127_1605419_6 Binding-protein-dependent transport system inner membrane component K02038 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 368.0
HKD1_k127_1605419_7 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 317.0
HKD1_k127_1605419_8 Two component transcriptional regulator, winged helix family K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006393 264.0
HKD1_k127_1605419_9 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001703 254.0
HKD1_k127_1625819_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1071.0
HKD1_k127_1625819_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 344.0
HKD1_k127_1625819_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001991 269.0
HKD1_k127_1625819_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000001605 76.0
HKD1_k127_1625819_4 FHA domain - - - 0.00000000000003113 79.0
HKD1_k127_1625819_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000008913 62.0
HKD1_k127_1639217_0 AraC type K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 616.0
HKD1_k127_1639217_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 547.0
HKD1_k127_1639217_10 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000001206 247.0
HKD1_k127_1639217_11 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 K18586 - - 0.000000000000000000000000000000000000000000000000000000000000007459 228.0
HKD1_k127_1639217_12 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000001563 218.0
HKD1_k127_1639217_13 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000000000001175 209.0
HKD1_k127_1639217_14 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000007213 219.0
HKD1_k127_1639217_15 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000002449 176.0
HKD1_k127_1639217_16 MaoC like domain - - - 0.0000000000000000000000000000000000000000004316 169.0
HKD1_k127_1639217_17 Pfam Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000007989 177.0
HKD1_k127_1639217_18 Methyltransferase domain - - - 0.0000000000000000000000000000000000000001397 169.0
HKD1_k127_1639217_19 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000001984 149.0
HKD1_k127_1639217_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 467.0
HKD1_k127_1639217_20 methyltransferase - - - 0.000000000000000000000000000000000001568 149.0
HKD1_k127_1639217_21 dehydratase - - - 0.00000000000000000000000000000000002163 141.0
HKD1_k127_1639217_22 endonuclease activity K07451 - - 0.0000000000000000000000000000003442 135.0
HKD1_k127_1639217_23 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000003894 135.0
HKD1_k127_1639217_24 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 K18586 - - 0.00000000000000000000000000000157 138.0
HKD1_k127_1639217_25 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000003275 102.0
HKD1_k127_1639217_26 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000008985 115.0
HKD1_k127_1639217_27 Belongs to the AAA ATPase family K13525 - - 0.00000000000000001059 94.0
HKD1_k127_1639217_28 Transcriptional regulator, Fis family - - - 0.00000000005058 75.0
HKD1_k127_1639217_29 DnaJ molecular chaperone homology domain - - - 0.00000000007776 75.0
HKD1_k127_1639217_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 484.0
HKD1_k127_1639217_30 Belongs to the ompA family - - - 0.0000000001254 70.0
HKD1_k127_1639217_31 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000003773 59.0
HKD1_k127_1639217_33 Domain of unknown function (DUF4388) - - - 0.00008742 55.0
HKD1_k127_1639217_4 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 373.0
HKD1_k127_1639217_5 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 394.0
HKD1_k127_1639217_6 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 372.0
HKD1_k127_1639217_7 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 313.0
HKD1_k127_1639217_8 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 312.0
HKD1_k127_1639217_9 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 295.0
HKD1_k127_1648775_0 PFAM Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 399.0
HKD1_k127_1648775_1 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 376.0
HKD1_k127_1648775_11 WLM domain - GO:0000731,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006508,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0018130,GO:0019438,GO:0019538,GO:0019985,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070011,GO:0071704,GO:0071897,GO:0090304,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.0002641 49.0
HKD1_k127_1648775_12 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0004641 51.0
HKD1_k127_1648775_2 Nitrite and sulphite reductase 4Fe-4S domain K00392 - 1.8.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 376.0
HKD1_k127_1648775_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 346.0
HKD1_k127_1648775_4 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 310.0
HKD1_k127_1648775_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000002691 252.0
HKD1_k127_1648775_6 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000006285 224.0
HKD1_k127_1648775_7 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000003455 177.0
HKD1_k127_1648775_8 to the N-terminal domain of Lon protease K07157 - - 0.000000000000000000000000000000007789 145.0
HKD1_k127_1648775_9 Dihydroneopterin aldolase - - - 0.000000000000001189 81.0
HKD1_k127_1667992_0 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 503.0
HKD1_k127_1667992_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 432.0
HKD1_k127_1667992_10 Acyl-ACP thioesterase K07107 - - 0.00000000000000000001219 104.0
HKD1_k127_1667992_11 RDD family - - - 0.0002081 53.0
HKD1_k127_1667992_2 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 358.0
HKD1_k127_1667992_3 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001498 286.0
HKD1_k127_1667992_4 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000002332 274.0
HKD1_k127_1667992_5 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001046 271.0
HKD1_k127_1667992_6 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000001513 245.0
HKD1_k127_1667992_7 Pectinacetylesterase - - - 0.0000000000000000000000000000000000000000000000000000000005829 228.0
HKD1_k127_1667992_8 Thioredoxin domain-containing protein K05838 - - 0.0000000000000000000000000000000000000000000000000002793 195.0
HKD1_k127_1667992_9 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000002216 187.0
HKD1_k127_1668298_0 PFAM Type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 363.0
HKD1_k127_1668298_1 PFAM Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 298.0
HKD1_k127_1668298_10 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000009435 75.0
HKD1_k127_1668298_11 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00004357 54.0
HKD1_k127_1668298_2 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003092 293.0
HKD1_k127_1668298_3 pfam abc K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005343 267.0
HKD1_k127_1668298_4 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000824 251.0
HKD1_k127_1668298_5 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000006035 234.0
HKD1_k127_1668298_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000919 176.0
HKD1_k127_1668298_7 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000001199 178.0
HKD1_k127_1668298_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000009239 157.0
HKD1_k127_1668298_9 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.000000000000008766 87.0
HKD1_k127_1695194_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.871e-248 779.0
HKD1_k127_1695194_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 6.526e-224 702.0
HKD1_k127_1695194_10 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 488.0
HKD1_k127_1695194_11 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 463.0
HKD1_k127_1695194_12 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 463.0
HKD1_k127_1695194_13 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 426.0
HKD1_k127_1695194_14 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 403.0
HKD1_k127_1695194_15 Glutamate-cysteine ligase family 2(GCS2) K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 398.0
HKD1_k127_1695194_16 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 376.0
HKD1_k127_1695194_17 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 346.0
HKD1_k127_1695194_18 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 353.0
HKD1_k127_1695194_19 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 321.0
HKD1_k127_1695194_2 TIGRFAM Ammonium transporter K03320 - - 3.702e-209 666.0
HKD1_k127_1695194_20 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001948 291.0
HKD1_k127_1695194_21 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005369 291.0
HKD1_k127_1695194_22 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000006249 285.0
HKD1_k127_1695194_23 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000001392 238.0
HKD1_k127_1695194_24 regulatory protein IclR - - - 0.00000000000000000000000000000000000000000000000000000000006003 215.0
HKD1_k127_1695194_25 HD domain - - - 0.000000000000000000000000000000000000000000000000000000001567 219.0
HKD1_k127_1695194_26 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000001196 207.0
HKD1_k127_1695194_27 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000003034 192.0
HKD1_k127_1695194_28 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000000000149 187.0
HKD1_k127_1695194_29 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000001018 134.0
HKD1_k127_1695194_3 Malic enzyme, NAD binding domain K00027,K00029,K00625,K04020,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 587.0
HKD1_k127_1695194_30 response regulator, receiver K02482 - 2.7.13.3 0.0000000000000000000000000000004399 138.0
HKD1_k127_1695194_31 Biotin-requiring enzyme - - - 0.0000000000000000000000000003192 132.0
HKD1_k127_1695194_32 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000000000001487 113.0
HKD1_k127_1695194_33 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000003434 125.0
HKD1_k127_1695194_34 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000004866 117.0
HKD1_k127_1695194_35 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000008193 128.0
HKD1_k127_1695194_36 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.000000000000000001056 98.0
HKD1_k127_1695194_37 Bacterial regulatory protein, Fis family - - - 0.00000000000000011 94.0
HKD1_k127_1695194_38 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000139 92.0
HKD1_k127_1695194_39 His Kinase A (phosphoacceptor) domain - - - 0.000000000001397 81.0
HKD1_k127_1695194_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 557.0
HKD1_k127_1695194_40 protein secretion K03116,K03117,K03646 - - 0.00000000002752 74.0
HKD1_k127_1695194_42 Acetyltransferase (GNAT) domain - - - 0.00003548 56.0
HKD1_k127_1695194_43 Tetratricopeptide repeat - - - 0.0004496 52.0
HKD1_k127_1695194_5 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 526.0
HKD1_k127_1695194_6 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 542.0
HKD1_k127_1695194_7 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 493.0
HKD1_k127_1695194_8 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 484.0
HKD1_k127_1695194_9 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007572 468.0
HKD1_k127_1697192_0 PFAM phenylalanine histidine ammonia-lyase K01745,K10774 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009698,GO:0009699,GO:0009987,GO:0016043,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0022607,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044550,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052883,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.3.1.23,4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 543.0
HKD1_k127_1697192_1 amp-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000959 369.0
HKD1_k127_1697192_10 Dehydratase - - - 0.0000000000000000000008882 110.0
HKD1_k127_1697192_11 acyl carrier protein K02078 - - 0.000000002502 64.0
HKD1_k127_1697192_2 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 308.0
HKD1_k127_1697192_3 Pfam Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002088 257.0
HKD1_k127_1697192_4 Fe-S protein K07140 GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0050896,GO:0098754 - 0.000000000000000000000000000000000000000000000000000000000000000000004548 243.0
HKD1_k127_1697192_5 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000848 220.0
HKD1_k127_1697192_6 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000001794 196.0
HKD1_k127_1697192_7 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000000006448 138.0
HKD1_k127_1697192_8 PFAM phospholipid glycerol acyltransferase - - - 0.000000000000000000000001822 105.0
HKD1_k127_1697192_9 synthase - - - 0.0000000000000000000000465 106.0
HKD1_k127_171556_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.951e-237 773.0
HKD1_k127_171556_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 5.525e-219 712.0
HKD1_k127_171556_10 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000009993 257.0
HKD1_k127_171556_11 NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000192 264.0
HKD1_k127_171556_12 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000008767 202.0
HKD1_k127_171556_14 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000006663 189.0
HKD1_k127_171556_15 Transcriptional Regulator, AraC family - - - 0.00000000000000000000000000000000000000000001976 178.0
HKD1_k127_171556_16 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000000000003078 160.0
HKD1_k127_171556_17 Threonylcarbamoyl adenosine biosynthesis protein TsaE K01775,K06925,K07102 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.1.221,5.1.1.1 0.000000000000000000001199 102.0
HKD1_k127_171556_19 dehydratase - - - 0.0000000000000005953 89.0
HKD1_k127_171556_2 Cytochrome bd-type quinol oxidase subunit 1 K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 557.0
HKD1_k127_171556_20 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.00000000000004694 81.0
HKD1_k127_171556_21 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000005075 81.0
HKD1_k127_171556_22 SLBB domain K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000007614 65.0
HKD1_k127_171556_23 YbbR-like protein - - - 0.00000005193 63.0
HKD1_k127_171556_24 AAA domain K02450 - - 0.00002255 57.0
HKD1_k127_171556_25 RNA processing - - - 0.00009724 54.0
HKD1_k127_171556_26 Glycosyl hydrolases family 25 - - - 0.0001073 54.0
HKD1_k127_171556_27 amine dehydrogenase activity - - - 0.0005836 53.0
HKD1_k127_171556_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 574.0
HKD1_k127_171556_4 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 505.0
HKD1_k127_171556_5 COG0798 Arsenite efflux pump ACR3 and related K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 482.0
HKD1_k127_171556_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 396.0
HKD1_k127_171556_7 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 391.0
HKD1_k127_171556_8 COG1294 Cytochrome bd-type quinol oxidase subunit 2 K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 377.0
HKD1_k127_171556_9 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000002085 269.0
HKD1_k127_1786337_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 400.0
HKD1_k127_1786337_1 Phenazine biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005525 282.0
HKD1_k127_1786337_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00612 - - 0.0000000000000002668 78.0
HKD1_k127_1786337_3 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000006046 84.0
HKD1_k127_1786337_4 MASE1 - - - 0.0000000000108 65.0
HKD1_k127_1868107_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1190.0
HKD1_k127_1868107_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 4.082e-232 740.0
HKD1_k127_1868107_10 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 476.0
HKD1_k127_1868107_11 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 444.0
HKD1_k127_1868107_12 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 398.0
HKD1_k127_1868107_13 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 391.0
HKD1_k127_1868107_14 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 336.0
HKD1_k127_1868107_15 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 308.0
HKD1_k127_1868107_16 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004641 295.0
HKD1_k127_1868107_17 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000002557 239.0
HKD1_k127_1868107_18 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000152 241.0
HKD1_k127_1868107_19 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000003374 213.0
HKD1_k127_1868107_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.894e-207 661.0
HKD1_k127_1868107_20 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000002725 130.0
HKD1_k127_1868107_21 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000003669 123.0
HKD1_k127_1868107_22 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000001367 119.0
HKD1_k127_1868107_23 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.000000000000000000004564 108.0
HKD1_k127_1868107_24 Protein of unknown function (DUF1329) - - - 0.0000000000000002169 93.0
HKD1_k127_1868107_25 - - - - 0.00000000000003252 83.0
HKD1_k127_1868107_26 Peptidoglycan-binding protein LysM - - - 0.000000007501 65.0
HKD1_k127_1868107_27 Tetratricopeptide repeat - - - 0.00002032 55.0
HKD1_k127_1868107_28 SMART helix-turn-helix domain protein K15539 - - 0.00003303 57.0
HKD1_k127_1868107_29 - - - - 0.0000429 56.0
HKD1_k127_1868107_3 Heat shock 70 kDa protein K04043 - - 8.895e-204 647.0
HKD1_k127_1868107_4 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 7.265e-195 614.0
HKD1_k127_1868107_5 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 568.0
HKD1_k127_1868107_6 C-terminal, D2-small domain, of ClpB protein K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 584.0
HKD1_k127_1868107_7 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 555.0
HKD1_k127_1868107_8 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 532.0
HKD1_k127_1868107_9 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 486.0
HKD1_k127_188563_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.477e-248 786.0
HKD1_k127_188563_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 352.0
HKD1_k127_188563_10 Belongs to the UPF0296 family K09777 - - 0.000000000000000000000000003708 117.0
HKD1_k127_188563_11 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000372 101.0
HKD1_k127_188563_12 Oxidoreductase family, NAD-binding Rossmann fold K00010 - 1.1.1.18,1.1.1.369 0.00000272 60.0
HKD1_k127_188563_2 Bifunctional protein K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000007814 268.0
HKD1_k127_188563_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005046 235.0
HKD1_k127_188563_4 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000002605 211.0
HKD1_k127_188563_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000004722 207.0
HKD1_k127_188563_6 PFAM glycosyl transferase family 9 K02843 - - 0.000000000000000000000000000000000000000000000000000009349 209.0
HKD1_k127_188563_7 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000156 194.0
HKD1_k127_188563_8 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000007157 169.0
HKD1_k127_188563_9 nUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000001232 168.0
HKD1_k127_191036_0 Translation-initiation factor 2 K02519 - - 4.418e-203 644.0
HKD1_k127_191036_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000002286 221.0
HKD1_k127_191036_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000003467 93.0
HKD1_k127_191036_3 Protein of unknown function (DUF503) K09764 - - 0.0000000000001839 82.0
HKD1_k127_1922094_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 3.973e-203 654.0
HKD1_k127_1922094_1 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 549.0
HKD1_k127_1922094_10 Belongs to the UPF0102 family K07460 - - 0.00000000000000000001206 102.0
HKD1_k127_1922094_11 Mannose-6-phosphate isomerase - - - 0.00000000003148 69.0
HKD1_k127_1922094_2 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003894 266.0
HKD1_k127_1922094_3 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000009228 229.0
HKD1_k127_1922094_4 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000004267 216.0
HKD1_k127_1922094_5 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K01784,K08678 - 4.1.1.35,4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000002901 198.0
HKD1_k127_1922094_6 - - - - 0.0000000000000000000000000000000000000000000000001129 190.0
HKD1_k127_1922094_7 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000002638 151.0
HKD1_k127_1922094_8 Glycosyl transferase family 4 - - - 0.00000000000000000000000000000005512 139.0
HKD1_k127_1922094_9 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000002271 142.0
HKD1_k127_1941985_0 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 418.0
HKD1_k127_1941985_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 333.0
HKD1_k127_1941985_2 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 328.0
HKD1_k127_1941985_3 belongs to the aldehyde dehydrogenase family K03400 - 1.2.1.50 0.00000000000000000000000000008251 126.0
HKD1_k127_1941985_4 DNA-binding transcriptional activator of the SARP family - - - 0.00000000000000000000002439 118.0
HKD1_k127_196699_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 420.0
HKD1_k127_196699_1 DNA polymerase A domain K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000004109 269.0
HKD1_k127_196699_2 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000002796 183.0
HKD1_k127_196699_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000003466 88.0
HKD1_k127_197245_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 533.0
HKD1_k127_197245_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 443.0
HKD1_k127_197245_10 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006484 293.0
HKD1_k127_197245_11 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000001148 229.0
HKD1_k127_197245_12 - - - - 0.00000000000000000000000000000000000000000000000000000009695 207.0
HKD1_k127_197245_13 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000005168 206.0
HKD1_k127_197245_14 Bacterial protein of unknown function (DUF899) K21701 - - 0.0000000000000000000000000000000000000000000001615 175.0
HKD1_k127_197245_15 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000003633 157.0
HKD1_k127_197245_16 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000006117 150.0
HKD1_k127_197245_17 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000458 135.0
HKD1_k127_197245_18 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000003573 118.0
HKD1_k127_197245_19 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000008615 111.0
HKD1_k127_197245_2 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 438.0
HKD1_k127_197245_20 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000005339 76.0
HKD1_k127_197245_21 - - - - 0.0000000000203 72.0
HKD1_k127_197245_22 Putative bacterial sensory transduction regulator - - - 0.000001598 62.0
HKD1_k127_197245_23 response regulator K02658 - - 0.000007799 58.0
HKD1_k127_197245_24 Heat shock 70 kDa protein K04043 - - 0.00001554 54.0
HKD1_k127_197245_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 384.0
HKD1_k127_197245_4 of the RND superfamily K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 409.0
HKD1_k127_197245_5 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 340.0
HKD1_k127_197245_6 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 329.0
HKD1_k127_197245_7 dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes K13356 - 1.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 322.0
HKD1_k127_197245_8 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 309.0
HKD1_k127_197245_9 Phosphoesterase family K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001477 299.0
HKD1_k127_1978072_0 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 558.0
HKD1_k127_1978072_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 390.0
HKD1_k127_1978072_2 COG4257 Streptogramin lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 368.0
HKD1_k127_1978072_3 CoA-transferase family III K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 309.0
HKD1_k127_1978072_5 transcriptional regulator K10913 - - 0.000000000000000000000000000000003716 138.0
HKD1_k127_1978072_6 - - - - 0.00000000000000000000000004266 124.0
HKD1_k127_1978072_7 O-Glycosyl hydrolase family 30 - - - 0.000000000000000000000004177 119.0
HKD1_k127_1978072_8 Protein conserved in bacteria K07114 - - 0.000000001651 66.0
HKD1_k127_202912_0 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 5.715e-315 991.0
HKD1_k127_202912_1 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 5.667e-223 728.0
HKD1_k127_202912_2 4Fe-4S dicluster domain K17048,K17051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 526.0
HKD1_k127_202912_3 Ethylbenzene dehydrogenase K17052 - - 0.0000000000000000000000000000000000000009663 157.0
HKD1_k127_202912_4 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000005733 153.0
HKD1_k127_2042125_0 FAD dependent oxidoreductase K15736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 347.0
HKD1_k127_2042125_1 nuclease activity - - - 0.0000000000000000000000000000000000000000000000002773 179.0
HKD1_k127_2078634_0 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 7.314e-269 852.0
HKD1_k127_2078634_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3 1.581e-233 777.0
HKD1_k127_2078634_10 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 382.0
HKD1_k127_2078634_11 Na+ dependent nucleoside transporter C-terminus K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 373.0
HKD1_k127_2078634_12 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 355.0
HKD1_k127_2078634_13 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 313.0
HKD1_k127_2078634_14 PFAM beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004587 306.0
HKD1_k127_2078634_15 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003112 278.0
HKD1_k127_2078634_16 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000008093 252.0
HKD1_k127_2078634_17 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000000002128 239.0
HKD1_k127_2078634_18 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000001778 219.0
HKD1_k127_2078634_19 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000001873 222.0
HKD1_k127_2078634_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 5.362e-231 748.0
HKD1_k127_2078634_20 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000007265 207.0
HKD1_k127_2078634_21 PaaX-like protein C-terminal domain K02616 - - 0.000000000000000000000000000000000000000000000000001169 193.0
HKD1_k127_2078634_22 oxidoreductase - - - 0.00000000000000000000000000000000000003212 156.0
HKD1_k127_2078634_23 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000002 141.0
HKD1_k127_2078634_24 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000005345 145.0
HKD1_k127_2078634_25 Major facilitator superfamily - - - 0.0000000000000000000000000001867 129.0
HKD1_k127_2078634_26 CBS domain K04767,K07168,K07182 - - 0.0000000000000000000000000002308 119.0
HKD1_k127_2078634_27 - - - - 0.0000000000000000000000009143 119.0
HKD1_k127_2078634_28 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000006964 115.0
HKD1_k127_2078634_29 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000003929 113.0
HKD1_k127_2078634_3 Cytochrome C oxidase subunit I K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 604.0
HKD1_k127_2078634_30 glycosyl transferase, family 39 - - - 0.000000000000000000003757 108.0
HKD1_k127_2078634_31 cyclic nucleotide-binding K10914 - - 0.00000000000000000000397 104.0
HKD1_k127_2078634_32 Lipid A Biosynthesis N-terminal domain - - - 0.000000000000000000009106 106.0
HKD1_k127_2078634_33 TIGRFAM Transcriptional regulator, Rrf2 - - - 0.00000000000000002605 90.0
HKD1_k127_2078634_34 Universal stress protein - - - 0.00000000000000003564 89.0
HKD1_k127_2078634_35 NnrU protein - - - 0.0000000000000731 82.0
HKD1_k127_2078634_36 - - - - 0.0000001474 61.0
HKD1_k127_2078634_37 Pfam Hemerythrin HHE - - - 0.0001892 51.0
HKD1_k127_2078634_38 - - - - 0.0003029 50.0
HKD1_k127_2078634_4 COG1055 Na H antiporter NhaD and related arsenite - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 569.0
HKD1_k127_2078634_5 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 564.0
HKD1_k127_2078634_6 response regulator K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 451.0
HKD1_k127_2078634_7 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 424.0
HKD1_k127_2078634_8 4Fe-4S dicluster domain K17048,K17051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 437.0
HKD1_k127_2078634_9 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 400.0
HKD1_k127_2107318_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 475.0
HKD1_k127_2107318_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000004859 199.0
HKD1_k127_2107318_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000006335 210.0
HKD1_k127_2107318_3 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000002893 154.0
HKD1_k127_2107318_5 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00004738 55.0
HKD1_k127_2107318_6 phosphorelay signal transduction system K02490 - - 0.00006543 56.0
HKD1_k127_2107318_7 periplasmic or secreted lipoprotein - - - 0.0002845 49.0
HKD1_k127_2108160_0 PFAM Aldehyde dehydrogenase K00128,K00130 - 1.2.1.3,1.2.1.8 5.95e-222 698.0
HKD1_k127_2108160_1 COG1960 Acyl-CoA dehydrogenases - - - 2.238e-197 628.0
HKD1_k127_2108160_2 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 430.0
HKD1_k127_2108160_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 366.0
HKD1_k127_2108160_4 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 314.0
HKD1_k127_2108160_5 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001444 278.0
HKD1_k127_2108160_6 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000117 274.0
HKD1_k127_2108160_7 Belongs to the CDS family K00981,K19664 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41,2.7.7.67 0.00000000008278 70.0
HKD1_k127_2120113_0 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002767 273.0
HKD1_k127_2120113_1 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000005661 160.0
HKD1_k127_2120113_2 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000007823 108.0
HKD1_k127_2120113_3 - - - - 0.000000000000004408 80.0
HKD1_k127_2124370_0 M18 family aminopeptidase K01267 - 3.4.11.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 480.0
HKD1_k127_2124370_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 443.0
HKD1_k127_2124370_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 317.0
HKD1_k127_2124370_3 Iron-regulated protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007796 266.0
HKD1_k127_2124370_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000001776 245.0
HKD1_k127_2124370_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000005331 104.0
HKD1_k127_2124370_6 Glycine-zipper domain - - - 0.0000000000000000002298 96.0
HKD1_k127_2138394_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 494.0
HKD1_k127_2138394_1 metal-dependent hydrolase of the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 482.0
HKD1_k127_2138394_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000001866 52.0
HKD1_k127_2138394_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 449.0
HKD1_k127_2138394_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 417.0
HKD1_k127_2138394_4 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 308.0
HKD1_k127_2138394_5 Evidence 2b Function of strongly homologous gene K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 297.0
HKD1_k127_2138394_6 pfam nudix - - - 0.00000000000000000000000000000000000000000000000005813 184.0
HKD1_k127_2138394_7 very-long-chain-acyl-CoA dehydrogenase activity K00249,K11729 GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0031974,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.8.7 0.000000000000000000000000000000000000000000000003713 181.0
HKD1_k127_2138394_8 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000001389 151.0
HKD1_k127_2138394_9 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000128 113.0
HKD1_k127_2194472_0 Glycosyl Transferase - - - 6.294e-265 847.0
HKD1_k127_2194472_1 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01576,K01652 - 2.2.1.6,4.1.1.7 3.259e-241 754.0
HKD1_k127_2194472_10 regulation of methylation-dependent chromatin silencing K07454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003827 257.0
HKD1_k127_2194472_11 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.00000000000000000000000000000000000000000000000000000000000000007127 243.0
HKD1_k127_2194472_12 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001291 218.0
HKD1_k127_2194472_13 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000000000000004103 218.0
HKD1_k127_2194472_14 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000194 207.0
HKD1_k127_2194472_15 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000001428 190.0
HKD1_k127_2194472_16 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000004836 101.0
HKD1_k127_2194472_18 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000003135 78.0
HKD1_k127_2194472_19 Haem-binding domain - - - 0.0000000000003275 76.0
HKD1_k127_2194472_2 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 554.0
HKD1_k127_2194472_20 PFAM Tetratricopeptide repeat - - - 0.0001223 54.0
HKD1_k127_2194472_21 Phosphotransferase K07028 - - 0.0002725 53.0
HKD1_k127_2194472_3 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 411.0
HKD1_k127_2194472_4 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007901 402.0
HKD1_k127_2194472_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 366.0
HKD1_k127_2194472_6 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008606 316.0
HKD1_k127_2194472_7 cytochrome P-450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 318.0
HKD1_k127_2194472_8 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 315.0
HKD1_k127_2194472_9 NnrU protein K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000003491 261.0
HKD1_k127_2197678_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 303.0
HKD1_k127_2197678_1 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 283.0
HKD1_k127_2197678_2 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002446 261.0
HKD1_k127_2197678_3 Helix-turn-helix domain - - - 0.000000000000000000007972 108.0
HKD1_k127_2199299_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1092.0
HKD1_k127_2199299_1 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 471.0
HKD1_k127_2199299_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000004872 235.0
HKD1_k127_2199299_3 Sulfurtransferase - - - 0.000000000000000000084 97.0
HKD1_k127_2199299_4 PFAM regulatory protein ArsR - - - 0.000000000000000001017 93.0
HKD1_k127_2199299_5 AMP binding - - - 0.0000000002637 63.0
HKD1_k127_2219484_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1230.0
HKD1_k127_2219484_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 294.0
HKD1_k127_2219484_2 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001012 250.0
HKD1_k127_2219484_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000006579 217.0
HKD1_k127_2219484_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000004752 176.0
HKD1_k127_2219484_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000007057 147.0
HKD1_k127_2219484_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000001798 76.0
HKD1_k127_2219484_7 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000007376 54.0
HKD1_k127_222463_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 481.0
HKD1_k127_222463_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 479.0
HKD1_k127_222463_10 PFAM metallophosphoesterase K07313 - 3.1.3.16 0.000000000000000000000000000000000000000232 158.0
HKD1_k127_222463_11 - - - - 0.0000000000000000000000000000000000193 139.0
HKD1_k127_222463_12 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000001729 138.0
HKD1_k127_222463_13 Biotin-requiring enzyme - - - 0.0000000000001869 82.0
HKD1_k127_222463_14 Belongs to the Nudix hydrolase family - - - 0.000000000006186 74.0
HKD1_k127_222463_15 Acetyltransferase (GNAT) family K06976 - - 0.00000002838 65.0
HKD1_k127_222463_2 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 396.0
HKD1_k127_222463_3 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 389.0
HKD1_k127_222463_4 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 361.0
HKD1_k127_222463_5 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 297.0
HKD1_k127_222463_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 304.0
HKD1_k127_222463_7 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001493 301.0
HKD1_k127_222463_8 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001962 282.0
HKD1_k127_222463_9 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000001101 184.0
HKD1_k127_2336341_0 TIGRFAM methylmalonyl-CoA mutase N-terminal domain - - - 3.008e-201 640.0
HKD1_k127_2336341_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 429.0
HKD1_k127_2336341_10 Glycosyl transferase family 2 - - - 0.000008954 52.0
HKD1_k127_2336341_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 373.0
HKD1_k127_2336341_3 ABC-type multidrug transport system ATPase and permease K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 388.0
HKD1_k127_2336341_4 lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000129 276.0
HKD1_k127_2336341_5 Catalyzes the addition of the first glucose residue to the LPS core K02844 - - 0.00000000000000000000000000000000000000000000000000000000000000000001481 264.0
HKD1_k127_2336341_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000009188 243.0
HKD1_k127_2336341_7 cobalamin binding - - - 0.000000000000000000000000000000000008834 156.0
HKD1_k127_2336341_8 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000005233 120.0
HKD1_k127_2336341_9 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000005972 88.0
HKD1_k127_2400906_0 Nitrous oxide reductase K00376 - 1.7.2.4 2.841e-268 843.0
HKD1_k127_2400906_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009612 406.0
HKD1_k127_2400906_2 quinone binding K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000137 296.0
HKD1_k127_2400906_3 Cytochrome c - - - 0.00000000000000000000000003381 115.0
HKD1_k127_2400906_4 - - - - 0.00000000000000000000003027 114.0
HKD1_k127_2400906_5 PFAM Cyclic nucleotide-binding K10914 - - 0.0000000000000000002149 98.0
HKD1_k127_2442080_0 Luciferase-like monooxygenase - - - 5.667e-208 654.0
HKD1_k127_2442080_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 553.0
HKD1_k127_2442080_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 530.0
HKD1_k127_2442080_3 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000000000000000000000000000000000000004575 210.0
HKD1_k127_2442080_4 chorismate binding enzyme K02552 - 5.4.4.2 0.000000000000000000000000000000000000000000000000000002223 214.0
HKD1_k127_2442080_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000007421 206.0
HKD1_k127_2442080_6 Peptidase family M28 - - - 0.00000000000000000000002227 115.0
HKD1_k127_2442080_7 helix_turn_helix, mercury resistance - - - 0.0000000000000000002591 97.0
HKD1_k127_2467100_0 PAS sensor protein K13243 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0008081,GO:0008144,GO:0008150,GO:0009628,GO:0016787,GO:0016788,GO:0019825,GO:0019826,GO:0020037,GO:0036094,GO:0042578,GO:0043167,GO:0043169,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0070482,GO:0071111,GO:0097159,GO:1901363 3.1.4.52 4.66e-237 767.0
HKD1_k127_2467100_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 454.0
HKD1_k127_2467100_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000003048 242.0
HKD1_k127_2467100_3 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000001023 184.0
HKD1_k127_2467100_4 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000007685 150.0
HKD1_k127_2467100_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000003443 138.0
HKD1_k127_2467100_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000003407 111.0
HKD1_k127_2467100_7 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000004589 93.0
HKD1_k127_2469751_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.055e-249 779.0
HKD1_k127_2469751_1 PFAM AMP-dependent synthetase and ligase K00666 - - 2.199e-203 659.0
HKD1_k127_2469751_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 312.0
HKD1_k127_2469751_11 Enoyl-(Acyl carrier protein) reductase K00038 - 1.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 299.0
HKD1_k127_2469751_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 289.0
HKD1_k127_2469751_13 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 307.0
HKD1_k127_2469751_14 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 299.0
HKD1_k127_2469751_15 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004226 284.0
HKD1_k127_2469751_16 COG2818 3-methyladenine DNA glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000001158 270.0
HKD1_k127_2469751_17 DnaJ C terminal domain K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002795 263.0
HKD1_k127_2469751_18 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005971 275.0
HKD1_k127_2469751_19 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002511 246.0
HKD1_k127_2469751_2 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 567.0
HKD1_k127_2469751_20 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001204 249.0
HKD1_k127_2469751_21 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005978 242.0
HKD1_k127_2469751_22 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000001195 235.0
HKD1_k127_2469751_23 dehydrogenase complex catalyzes the overall conversion of - - - 0.000000000000000000000000000000000000000000000000000000241 203.0
HKD1_k127_2469751_24 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000003323 192.0
HKD1_k127_2469751_25 redox protein regulator of disulfide bond formation - - - 0.00000000000000000000000000000000000000000003464 185.0
HKD1_k127_2469751_26 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000002133 167.0
HKD1_k127_2469751_27 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000002259 171.0
HKD1_k127_2469751_28 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000002538 166.0
HKD1_k127_2469751_29 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000001049 159.0
HKD1_k127_2469751_3 Pyridoxal-dependent decarboxylase conserved domain K01580,K13745 - 4.1.1.15,4.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 543.0
HKD1_k127_2469751_30 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000004367 138.0
HKD1_k127_2469751_31 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000002354 141.0
HKD1_k127_2469751_32 YhhN family - - - 0.000000000000000000000000000000121 145.0
HKD1_k127_2469751_33 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000007159 116.0
HKD1_k127_2469751_34 Acetyltransferase (GNAT) domain - - - 0.0000000000000005106 86.0
HKD1_k127_2469751_35 transcriptional regulator - - - 0.000003001 59.0
HKD1_k127_2469751_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 400.0
HKD1_k127_2469751_5 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 400.0
HKD1_k127_2469751_6 fad dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 382.0
HKD1_k127_2469751_7 Thioesterase-like superfamily K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 367.0
HKD1_k127_2469751_8 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 346.0
HKD1_k127_2469751_9 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 338.0
HKD1_k127_2472054_0 Dehydrogenase K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 2.705e-260 820.0
HKD1_k127_2472054_1 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 7.623e-199 653.0
HKD1_k127_2472054_10 Glutathione S-transferase K00799,K03599 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000001387 230.0
HKD1_k127_2472054_11 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000003296 216.0
HKD1_k127_2472054_12 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000008026 201.0
HKD1_k127_2472054_13 PAS PAC sensor signal transduction histidine kinase K19661 - 2.7.13.3 0.00000000000000000000000000000000000000003611 174.0
HKD1_k127_2472054_14 OmpA family - - - 0.0000000000005827 77.0
HKD1_k127_2472054_15 transcriptional regulator - - - 0.00000000006873 74.0
HKD1_k127_2472054_16 CoA-binding domain protein - - - 0.00000008056 55.0
HKD1_k127_2472054_17 Cytochrome c3 - - - 0.000000651 59.0
HKD1_k127_2472054_18 lipolytic protein G-D-S-L family - - - 0.0002062 55.0
HKD1_k127_2472054_2 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 598.0
HKD1_k127_2472054_3 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 513.0
HKD1_k127_2472054_4 antibiotic catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 499.0
HKD1_k127_2472054_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 438.0
HKD1_k127_2472054_6 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 326.0
HKD1_k127_2472054_7 Enoyl-CoA hydratase/isomerase K08299 - 4.2.1.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 313.0
HKD1_k127_2472054_8 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001939 298.0
HKD1_k127_2472054_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009677 266.0
HKD1_k127_2524873_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 378.0
HKD1_k127_2524873_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 308.0
HKD1_k127_2524873_2 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000008333 256.0
HKD1_k127_2524873_3 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000007655 222.0
HKD1_k127_2524873_4 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000000006951 151.0
HKD1_k127_2524873_5 Recombinase - - - 0.000000000000000000000000001274 123.0
HKD1_k127_2524873_6 response regulator - - - 0.000000000000000000003758 103.0
HKD1_k127_2524873_7 - - - - 0.00002177 48.0
HKD1_k127_2524873_8 - - - - 0.0002915 50.0
HKD1_k127_2555672_0 PFAM cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 362.0
HKD1_k127_2555672_1 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 355.0
HKD1_k127_2555672_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000036 219.0
HKD1_k127_2555672_3 trisaccharide binding - - - 0.000000000000000000000000000000000000000000000000000000000005809 213.0
HKD1_k127_2555672_4 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000006474 184.0
HKD1_k127_2555672_5 isomerase activity K01821 - 5.3.2.6 0.000000000000000000000002592 121.0
HKD1_k127_2555672_6 Domain of Unknown Function (DUF748) - - - 0.000000000000000002698 101.0
HKD1_k127_2572799_0 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 479.0
HKD1_k127_2572799_1 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 422.0
HKD1_k127_2572799_2 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 312.0
HKD1_k127_2572799_3 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000002552 206.0
HKD1_k127_2572799_4 Glycine zipper - - - 0.000000000000000000000000002711 128.0
HKD1_k127_2572799_5 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000217 89.0
HKD1_k127_2572799_6 repeat protein - - - 0.00000000005603 75.0
HKD1_k127_257549_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 317.0
HKD1_k127_257549_1 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007902 260.0
HKD1_k127_257549_2 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000006453 244.0
HKD1_k127_257549_3 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000006286 111.0
HKD1_k127_257549_4 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000002192 102.0
HKD1_k127_2596133_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 474.0
HKD1_k127_2596133_1 drug resistance transporter, EmrB QacA subfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 469.0
HKD1_k127_2596133_10 PFAM FecR protein K01179,K03933 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000001809 233.0
HKD1_k127_2596133_11 PFAM aldo keto reductase K07079 - - 0.00000000000000000000000000000000000001226 161.0
HKD1_k127_2596133_12 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000003597 155.0
HKD1_k127_2596133_13 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000006173 133.0
HKD1_k127_2596133_14 SnoaL-like domain - - - 0.000000000000000000000003435 109.0
HKD1_k127_2596133_15 Protein of unknown function (DUF1329) - - - 0.0000000000000000000006787 112.0
HKD1_k127_2596133_16 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000223 103.0
HKD1_k127_2596133_17 PFAM regulatory protein TetR - - - 0.0000000000000000003553 98.0
HKD1_k127_2596133_18 ErfK YbiS YcfS YnhG - - - 0.00000000424 64.0
HKD1_k127_2596133_19 peptidyl-tyrosine sulfation - - - 0.0000002466 65.0
HKD1_k127_2596133_2 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 449.0
HKD1_k127_2596133_3 PFAM LOR SDH bifunctional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 436.0
HKD1_k127_2596133_4 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 398.0
HKD1_k127_2596133_5 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 329.0
HKD1_k127_2596133_6 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004051 283.0
HKD1_k127_2596133_7 PFAM amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 259.0
HKD1_k127_2596133_8 tRNA nucleotidyltransferase domain 2 putative K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000001509 254.0
HKD1_k127_2596133_9 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000416 236.0
HKD1_k127_2610039_0 Transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 306.0
HKD1_k127_2639728_0 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 568.0
HKD1_k127_2639728_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 577.0
HKD1_k127_2639728_10 SnoaL-like domain - - - 0.0000000336 66.0
HKD1_k127_2639728_2 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 550.0
HKD1_k127_2639728_3 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 356.0
HKD1_k127_2639728_4 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006313 279.0
HKD1_k127_2639728_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000016 215.0
HKD1_k127_2639728_6 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000101 197.0
HKD1_k127_2639728_7 oxidoreductase activity, acting on CH-OH group of donors K03520,K09386 - 1.2.5.3 0.000000000000000000000000000000000000000000005638 188.0
HKD1_k127_2639728_8 - - - - 0.000000000000000000000000007075 114.0
HKD1_k127_2639728_9 acetone carboxylase, alpha subunit K10854 - 6.4.1.6 0.000000002665 65.0
HKD1_k127_2657166_0 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 471.0
HKD1_k127_2657166_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 388.0
HKD1_k127_2657166_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000002604 230.0
HKD1_k127_2657166_3 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000000000002113 216.0
HKD1_k127_2657166_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000006389 84.0
HKD1_k127_2670241_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 527.0
HKD1_k127_2670241_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 432.0
HKD1_k127_2670241_10 Mannose-6-phosphate isomerase - - - 0.0000000000004346 71.0
HKD1_k127_2670241_11 ThiS family K03154 - - 0.000000000002317 70.0
HKD1_k127_2670241_12 Protein of unknown function (DUF721) - - - 0.00000000009402 75.0
HKD1_k127_2670241_13 Belongs to the UPF0109 family K06960 - - 0.0000000004883 70.0
HKD1_k127_2670241_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 336.0
HKD1_k127_2670241_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000005375 265.0
HKD1_k127_2670241_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000005823 250.0
HKD1_k127_2670241_5 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000002508 237.0
HKD1_k127_2670241_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000009038 159.0
HKD1_k127_2670241_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - - - 0.00000000000000000000000924 119.0
HKD1_k127_2670241_8 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000000005655 100.0
HKD1_k127_2670241_9 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000002427 89.0
HKD1_k127_2690744_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 8.372e-302 945.0
HKD1_k127_2690744_1 - K20614 - 4.2.1.127,5.4.4.4 8.905e-235 743.0
HKD1_k127_2690744_10 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 464.0
HKD1_k127_2690744_11 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 398.0
HKD1_k127_2690744_12 PFAM 2-nitropropane dioxygenase NPD K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 377.0
HKD1_k127_2690744_13 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 385.0
HKD1_k127_2690744_14 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 344.0
HKD1_k127_2690744_15 Bifunctional DNA primase/polymerase, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 312.0
HKD1_k127_2690744_16 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 304.0
HKD1_k127_2690744_17 Enoyl-(Acyl carrier protein) reductase K03366 - 1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 305.0
HKD1_k127_2690744_18 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000378 288.0
HKD1_k127_2690744_19 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001533 267.0
HKD1_k127_2690744_2 Carboxyl transferase domain - - - 1.819e-212 672.0
HKD1_k127_2690744_20 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005856 268.0
HKD1_k127_2690744_21 surface antigen K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002378 275.0
HKD1_k127_2690744_22 UDP-glucoronosyl and UDP-glucosyl transferase K16444 - 2.4.1.310 0.0000000000000000000000000000000000000000000000000000000000000000000009731 267.0
HKD1_k127_2690744_23 RNA pseudouridylate synthase K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000000000000000000006666 225.0
HKD1_k127_2690744_24 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000000000000000000000000000000466 200.0
HKD1_k127_2690744_25 Fungal family of unknown function (DUF1776) - - - 0.00000000000000000000000000000000000000000000000001805 202.0
HKD1_k127_2690744_26 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.000000000000000000000000000000000000006171 170.0
HKD1_k127_2690744_27 PFAM Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.00000000000000000000000000000000000004176 153.0
HKD1_k127_2690744_28 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000003291 154.0
HKD1_k127_2690744_29 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000005086 134.0
HKD1_k127_2690744_3 4-hydroxyphenylacetate K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 4.345e-212 671.0
HKD1_k127_2690744_30 glycosyl transferase family - - - 0.0000000000000000000000000000000605 139.0
HKD1_k127_2690744_31 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000003651 115.0
HKD1_k127_2690744_32 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000003278 102.0
HKD1_k127_2690744_33 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K03183 - 2.1.1.163,2.1.1.201 0.0002743 47.0
HKD1_k127_2690744_34 Cytochrome c - - - 0.0004391 44.0
HKD1_k127_2690744_4 Thiolase, C-terminal domain K00626 - 2.3.1.9 4.272e-206 645.0
HKD1_k127_2690744_5 peptidase, M20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 608.0
HKD1_k127_2690744_6 Flavoprotein involved in K transport K03379 - 1.14.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 541.0
HKD1_k127_2690744_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 525.0
HKD1_k127_2690744_8 Biotin carboxylase C-terminal domain K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 525.0
HKD1_k127_2690744_9 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 535.0
HKD1_k127_2698756_0 PFAM AMP-dependent synthetase and ligase K00666 - - 5.197e-312 985.0
HKD1_k127_2698756_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 526.0
HKD1_k127_2698756_2 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 357.0
HKD1_k127_2698756_3 RecQ zinc-binding K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 338.0
HKD1_k127_2698756_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 314.0
HKD1_k127_2698756_5 DNA helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000006992 163.0
HKD1_k127_2698756_6 BolA-like protein - - - 0.00000000000000005247 94.0
HKD1_k127_2698756_7 CBS domain - - - 0.00000000000000109 92.0
HKD1_k127_270387_0 Mismatch repair ATPase (MutS family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 602.0
HKD1_k127_270387_1 radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 563.0
HKD1_k127_270387_2 arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005117 277.0
HKD1_k127_270387_3 Phosphomethylpyrimidine kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000893 72.0
HKD1_k127_2707761_0 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 614.0
HKD1_k127_2707761_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 519.0
HKD1_k127_2707761_10 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000001852 173.0
HKD1_k127_2707761_11 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000136 148.0
HKD1_k127_2707761_12 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000009724 137.0
HKD1_k127_2707761_13 Belongs to the heat shock protein 70 family K04046 - - 0.0000000000000000000000000000001255 126.0
HKD1_k127_2707761_14 alpha-ribazole phosphatase activity K02226,K15634,K15640 - 3.1.3.73,5.4.2.12 0.00000000000000000000000000004832 131.0
HKD1_k127_2707761_15 PFAM Smr protein MutS2 - - - 0.000000000000000000000000005005 123.0
HKD1_k127_2707761_16 Diphthamide synthase - - - 0.00001341 58.0
HKD1_k127_2707761_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 507.0
HKD1_k127_2707761_3 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K17736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 390.0
HKD1_k127_2707761_4 Belongs to the heat shock protein 70 family K04046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 312.0
HKD1_k127_2707761_5 A G-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 316.0
HKD1_k127_2707761_6 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 307.0
HKD1_k127_2707761_7 ThiJ PfpI - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004507 269.0
HKD1_k127_2707761_8 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000125 232.0
HKD1_k127_2707761_9 Sugar fermentation stimulation protein K06206 - - 0.0000000000000000000000000000000000000000000000000000006213 201.0
HKD1_k127_2745781_0 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008604 399.0
HKD1_k127_2745781_1 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001844 285.0
HKD1_k127_2745781_2 Protein of unknown function, DUF255 K06888 - - 0.000001032 53.0
HKD1_k127_2746071_0 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 443.0
HKD1_k127_2746071_1 ATP-binding region ATPase domain protein, response regulator receiver, histidine kinase A domain protein - - - 0.000000000000000000000000000001341 126.0
HKD1_k127_2746071_2 universal stress protein - - - 0.0002651 49.0
HKD1_k127_2766872_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.363e-218 695.0
HKD1_k127_2766872_1 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 502.0
HKD1_k127_2766872_11 Protein of unknown function, DUF481 K07283 - - 0.00000000000000000000000000000286 133.0
HKD1_k127_2766872_12 radical SAM domain protein - - - 0.0000000000000000000000000000181 130.0
HKD1_k127_2766872_13 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000003819 136.0
HKD1_k127_2766872_14 PGAP1-like protein - - - 0.0000000000000000000000002046 122.0
HKD1_k127_2766872_15 YCII-related domain - - - 0.00000000000000000000001347 104.0
HKD1_k127_2766872_16 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000321 103.0
HKD1_k127_2766872_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 429.0
HKD1_k127_2766872_3 Belongs to the sigma-70 factor family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 372.0
HKD1_k127_2766872_4 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007149 293.0
HKD1_k127_2766872_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000002628 228.0
HKD1_k127_2766872_6 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000001056 223.0
HKD1_k127_2766872_7 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000006252 222.0
HKD1_k127_2766872_8 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000004817 180.0
HKD1_k127_2766872_9 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000004135 172.0
HKD1_k127_2891037_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 549.0
HKD1_k127_2921930_0 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 552.0
HKD1_k127_2921930_1 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 394.0
HKD1_k127_2921930_10 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000565 63.0
HKD1_k127_2921930_11 Cytochrome c - - - 0.0000003741 64.0
HKD1_k127_2921930_12 Cytochrome c - - - 0.000004447 61.0
HKD1_k127_2921930_13 Two component regulator propeller - - - 0.00008501 55.0
HKD1_k127_2921930_2 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 327.0
HKD1_k127_2921930_3 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000001367 250.0
HKD1_k127_2921930_4 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000003363 184.0
HKD1_k127_2921930_5 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000001511 167.0
HKD1_k127_2921930_6 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000002879 153.0
HKD1_k127_2921930_7 CcmB protein K02194 - - 0.0000000000000000000000000000000000001081 155.0
HKD1_k127_2921930_8 PFAM nucleic acid binding, OB-fold, tRNA - - - 0.00000000000000000003811 98.0
HKD1_k127_2921930_9 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.0000000000000000002174 96.0
HKD1_k127_294014_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 434.0
HKD1_k127_294014_1 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001729 273.0
HKD1_k127_294014_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000005385 237.0
HKD1_k127_2960476_0 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 441.0
HKD1_k127_2960476_1 ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 421.0
HKD1_k127_2960476_2 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000002169 177.0
HKD1_k127_2960476_3 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.00000000000000000000000000000000000000000001878 175.0
HKD1_k127_2960476_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000001815 126.0
HKD1_k127_2960476_5 sigma-54 factor interaction domain-containing protein K07714 - - 0.00001433 52.0
HKD1_k127_2974815_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 564.0
HKD1_k127_2974815_1 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 340.0
HKD1_k127_2974815_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000005998 230.0
HKD1_k127_2974815_3 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000000000000000000003501 217.0
HKD1_k127_2974815_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000003283 171.0
HKD1_k127_2974815_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000001746 87.0
HKD1_k127_3011987_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 336.0
HKD1_k127_3011987_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 306.0
HKD1_k127_3011987_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000001102 137.0
HKD1_k127_3028492_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 3.905e-219 692.0
HKD1_k127_3028492_1 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 336.0
HKD1_k127_3028492_2 Putative serine esterase (DUF676) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 310.0
HKD1_k127_3028492_3 alpha beta - - - 0.0000000000000000001126 102.0
HKD1_k127_3028492_4 bacterial OsmY and nodulation domain K04065 - - 0.000000000001002 81.0
HKD1_k127_3028492_5 periplasmic or secreted lipoprotein K04065 - - 0.00000002401 66.0
HKD1_k127_307206_0 alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 426.0
HKD1_k127_307206_1 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 332.0
HKD1_k127_307206_10 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000266 160.0
HKD1_k127_307206_11 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000004262 149.0
HKD1_k127_307206_12 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000001474 125.0
HKD1_k127_307206_13 Domain of unknown function (DUF4262) - - - 0.000000000000000000000000004044 129.0
HKD1_k127_307206_14 - - - - 0.0000000000000000001013 103.0
HKD1_k127_307206_15 phosphoglycolate phosphatase activity - - - 0.0000000000000305 83.0
HKD1_k127_307206_16 Antibiotic biosynthesis monooxygenase - - - 0.00000000000005233 83.0
HKD1_k127_307206_17 PFAM Abortive infection protein K07052 - - 0.000000000002267 78.0
HKD1_k127_307206_18 Thioesterase-like superfamily - - - 0.000000000584 70.0
HKD1_k127_307206_19 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000172 61.0
HKD1_k127_307206_2 Superfamily II DNA RNA helicases, SNF2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000002307 225.0
HKD1_k127_307206_20 protein possibly involved in aromatic compounds catabolism - - - 0.00002707 55.0
HKD1_k127_307206_21 pilus assembly - - - 0.0008131 52.0
HKD1_k127_307206_3 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000001406 207.0
HKD1_k127_307206_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000001805 206.0
HKD1_k127_307206_5 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000001113 198.0
HKD1_k127_307206_6 Putative PD-(D/E)XK phosphodiesterase (DUF2161) - - - 0.00000000000000000000000000000000000000000000000000001854 199.0
HKD1_k127_307206_7 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000004749 205.0
HKD1_k127_307206_8 penicillin-binding protein - - - 0.0000000000000000000000000000000000000000000000647 191.0
HKD1_k127_307206_9 COG0694 Thioredoxin-like proteins and domains - - - 0.00000000000000000000000000000000000000000002867 168.0
HKD1_k127_3125861_0 PQQ-like domain K00117 - 1.1.5.2 5.711e-217 705.0
HKD1_k127_3125861_1 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 490.0
HKD1_k127_3125861_10 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.0000000000000000000000000000000000000000000000005104 192.0
HKD1_k127_3125861_11 HAD-hyrolase-like K07025 - - 0.00000000000000000000000000000000000000004673 160.0
HKD1_k127_3125861_12 transcriptional regulator - - - 0.00000000000000000000000000000000000000156 156.0
HKD1_k127_3125861_13 cellular response to DNA damage stimulus K07340 - - 0.000000000000000000000000000002 132.0
HKD1_k127_3125861_14 Membrane - - - 0.00000000000002452 87.0
HKD1_k127_3125861_15 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.0000000000001598 84.0
HKD1_k127_3125861_17 Phosphopantetheine attachment site - - - 0.0000003882 60.0
HKD1_k127_3125861_2 PFAM gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 460.0
HKD1_k127_3125861_3 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 417.0
HKD1_k127_3125861_4 Reductase C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 394.0
HKD1_k127_3125861_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 387.0
HKD1_k127_3125861_6 Tryptophan halogenase K14257 - 1.14.19.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 351.0
HKD1_k127_3125861_7 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 355.0
HKD1_k127_3125861_8 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000004185 251.0
HKD1_k127_3125861_9 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000388 224.0
HKD1_k127_3139279_0 Dehydrogenase E1 component K00164 - 1.2.4.2 5.561e-292 926.0
HKD1_k127_3139279_1 COG0183 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 409.0
HKD1_k127_3139279_10 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000007973 202.0
HKD1_k127_3139279_11 protein involved in response to NO K07234 - - 0.0000000000000000000000000000000000004316 159.0
HKD1_k127_3139279_12 Transcriptional regulator - - - 0.0000000000000000000000000000000000005111 145.0
HKD1_k127_3139279_13 integral membrane protein - - - 0.0000000000000000000000000000000001265 138.0
HKD1_k127_3139279_14 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000005784 132.0
HKD1_k127_3139279_15 Rhodanese Homology Domain - - - 0.00000000000000000000000139 111.0
HKD1_k127_3139279_16 - - - - 0.000000000000000000000003884 115.0
HKD1_k127_3139279_17 Domain of unknown function (DUF3332) - - - 0.00000000000000000001449 102.0
HKD1_k127_3139279_18 Cupin 2, conserved barrel domain protein - - - 0.00000000000000001542 89.0
HKD1_k127_3139279_2 Anthranilate synthase component I, N terminal region K01665,K03342 - 2.6.1.85,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 370.0
HKD1_k127_3139279_3 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 339.0
HKD1_k127_3139279_4 PFAM alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 329.0
HKD1_k127_3139279_5 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 314.0
HKD1_k127_3139279_6 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000004081 257.0
HKD1_k127_3139279_7 response regulator K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001166 257.0
HKD1_k127_3139279_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000001139 248.0
HKD1_k127_3139279_9 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000201 223.0
HKD1_k127_3161333_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.319e-284 911.0
HKD1_k127_3161333_1 tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 553.0
HKD1_k127_3161333_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 571.0
HKD1_k127_3161333_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000006746 190.0
HKD1_k127_3161333_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000001971 177.0
HKD1_k127_3161333_5 aspartic-type endopeptidase activity K06985 - - 0.000000000000003029 90.0
HKD1_k127_3161333_6 outer membrane efflux protein - - - 0.00000000002784 75.0
HKD1_k127_3189362_0 Glycosyl transferase, family 2 - - - 1.241e-280 887.0
HKD1_k127_3189362_1 MMPL family K07003 - - 1.728e-267 854.0
HKD1_k127_3189362_10 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 477.0
HKD1_k127_3189362_11 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 391.0
HKD1_k127_3189362_12 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 362.0
HKD1_k127_3189362_13 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 359.0
HKD1_k127_3189362_14 Glucokinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 333.0
HKD1_k127_3189362_15 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 331.0
HKD1_k127_3189362_16 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002126 262.0
HKD1_k127_3189362_17 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002201 267.0
HKD1_k127_3189362_18 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000000000000001816 199.0
HKD1_k127_3189362_19 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000001625 192.0
HKD1_k127_3189362_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.13e-245 776.0
HKD1_k127_3189362_20 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000002717 182.0
HKD1_k127_3189362_21 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.000000000000000000000000000000000000008713 155.0
HKD1_k127_3189362_22 Bacterial regulatory proteins, tetR family K22107 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0042803,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000001024 124.0
HKD1_k127_3189362_23 Divergent 4Fe-4S mono-cluster K05337 - - 0.000000000000000001485 91.0
HKD1_k127_3189362_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 2.106e-234 751.0
HKD1_k127_3189362_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.15e-213 693.0
HKD1_k127_3189362_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 9.805e-210 703.0
HKD1_k127_3189362_6 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 617.0
HKD1_k127_3189362_7 AMP-binding enzyme C-terminal domain K18688 - 6.2.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 584.0
HKD1_k127_3189362_8 PFAM ABC transporter, transmembrane region K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 541.0
HKD1_k127_3189362_9 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 495.0
HKD1_k127_3190909_0 ABC transporter K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 521.0
HKD1_k127_3190909_1 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 449.0
HKD1_k127_3190909_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 321.0
HKD1_k127_3190909_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000004963 156.0
HKD1_k127_3191480_0 PFAM Major facilitator superfamily K08178 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 522.0
HKD1_k127_3191480_1 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 496.0
HKD1_k127_3191480_10 - - - - 0.00000000000000000000000000005979 123.0
HKD1_k127_3191480_11 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000003988 92.0
HKD1_k127_3191480_12 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.000000000000000001008 91.0
HKD1_k127_3191480_13 Alpha beta hydrolase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000002786 82.0
HKD1_k127_3191480_14 PFAM Cyclic nucleotide-binding K10914,K21563 - - 0.000000000000003704 87.0
HKD1_k127_3191480_15 DNA integration K14059 - - 0.0000000002 70.0
HKD1_k127_3191480_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 370.0
HKD1_k127_3191480_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 360.0
HKD1_k127_3191480_4 Cytochrome P450 K15981 - 1.14.13.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 329.0
HKD1_k127_3191480_5 PFAM CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008849 290.0
HKD1_k127_3191480_6 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000004896 211.0
HKD1_k127_3191480_7 Regulatory protein, MerR - - - 0.0000000000000000000000000000000000000000000000000009934 193.0
HKD1_k127_3191480_8 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000001049 168.0
HKD1_k127_3191480_9 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000003188 151.0
HKD1_k127_3194557_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 7.365e-275 878.0
HKD1_k127_3194557_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.643e-265 825.0
HKD1_k127_3194557_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000003007 156.0
HKD1_k127_3194557_11 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000002905 130.0
HKD1_k127_3194557_12 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000002403 128.0
HKD1_k127_3194557_13 - - - - 0.0000000000000000000000003912 108.0
HKD1_k127_3194557_14 - - - - 0.000000000000000000001866 100.0
HKD1_k127_3194557_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000003949 86.0
HKD1_k127_3194557_17 Methyltransferase domain - - - 0.000008203 51.0
HKD1_k127_3194557_18 - - - - 0.00001178 51.0
HKD1_k127_3194557_19 peptidyl-tyrosine sulfation - - - 0.0003843 53.0
HKD1_k127_3194557_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 533.0
HKD1_k127_3194557_3 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 447.0
HKD1_k127_3194557_4 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001116 294.0
HKD1_k127_3194557_5 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000003483 258.0
HKD1_k127_3194557_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000004025 197.0
HKD1_k127_3194557_7 PFAM MAPEG family - - - 0.0000000000000000000000000000000000000000000000009688 179.0
HKD1_k127_3194557_8 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000002558 193.0
HKD1_k127_3194557_9 - - - - 0.0000000000000000000000000000000000000000000005101 191.0
HKD1_k127_3212429_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1046.0
HKD1_k127_3212429_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 1.012e-208 669.0
HKD1_k127_3212429_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 5.565e-206 670.0
HKD1_k127_3212429_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 385.0
HKD1_k127_3212429_4 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 321.0
HKD1_k127_3212429_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002269 287.0
HKD1_k127_3212429_6 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000006905 228.0
HKD1_k127_3212429_7 PFAM Cyclic nucleotide-binding - - - 0.000002065 61.0
HKD1_k127_3212914_0 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1965.0
HKD1_k127_3212914_1 'glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 1.059e-204 647.0
HKD1_k127_3212914_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 424.0
HKD1_k127_3212914_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 398.0
HKD1_k127_3212914_4 PFAM glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000009704 152.0
HKD1_k127_3212914_5 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000008212 144.0
HKD1_k127_3212914_7 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000008402 114.0
HKD1_k127_3212914_8 - - - - 0.000000000000003766 78.0
HKD1_k127_3212914_9 Cell division protein ZapA K09888 - - 0.0000006385 58.0
HKD1_k127_3260349_0 Thiolase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 586.0
HKD1_k127_3260349_1 CoA-transferase family III K07544 - 2.8.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 579.0
HKD1_k127_3260349_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 526.0
HKD1_k127_3260349_3 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 470.0
HKD1_k127_3260349_4 Enoyl-CoA hydratase/isomerase K07546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 359.0
HKD1_k127_3260349_5 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000222 281.0
HKD1_k127_3260349_6 Electron transfer flavoprotein alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001211 260.0
HKD1_k127_3260349_7 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000000000000000000000000007217 164.0
HKD1_k127_3260349_8 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000001054 128.0
HKD1_k127_3260349_9 COG0183 Acetyl-CoA acetyltransferase - - - 0.00000000009947 63.0
HKD1_k127_3262549_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1231.0
HKD1_k127_3262549_1 Aldehyde dehydrogenase K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 0.0 1129.0
HKD1_k127_3262549_10 PEP-CTERM motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001189 260.0
HKD1_k127_3262549_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000983 271.0
HKD1_k127_3262549_12 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000001509 222.0
HKD1_k127_3262549_13 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000001932 182.0
HKD1_k127_3262549_14 - - - - 0.00000000000000000000000000000000000000001147 161.0
HKD1_k127_3262549_15 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity - - - 0.0000000000000000000004093 109.0
HKD1_k127_3262549_17 outer membrane efflux protein K15725 - - 0.00000000000000003734 95.0
HKD1_k127_3262549_18 amine dehydrogenase activity - - - 0.0000000000000007994 87.0
HKD1_k127_3262549_20 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000001305 58.0
HKD1_k127_3262549_3 Cytochrome P450 - GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 491.0
HKD1_k127_3262549_4 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 449.0
HKD1_k127_3262549_5 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 387.0
HKD1_k127_3262549_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 382.0
HKD1_k127_3262549_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 358.0
HKD1_k127_3262549_8 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 353.0
HKD1_k127_3262549_9 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001024 284.0
HKD1_k127_3368304_0 ATPase family associated with various cellular activities (AAA) K06027 - 3.6.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 539.0
HKD1_k127_3368304_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 496.0
HKD1_k127_3368304_10 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000002343 229.0
HKD1_k127_3368304_11 Acetoacetate decarboxylase (ADC) - - - 0.000000000000000000000000000000000000000000000000000002214 201.0
HKD1_k127_3368304_12 Cytochrome c - - - 0.00000000000000000000000000000000000000000000003962 179.0
HKD1_k127_3368304_13 Radical SAM - - - 0.0000000000000000000000000000000000000000000001819 189.0
HKD1_k127_3368304_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000009681 182.0
HKD1_k127_3368304_15 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000018 146.0
HKD1_k127_3368304_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000001691 145.0
HKD1_k127_3368304_17 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000005418 119.0
HKD1_k127_3368304_18 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000003506 101.0
HKD1_k127_3368304_19 SNARE associated Golgi protein - - - 0.00000000257 61.0
HKD1_k127_3368304_2 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 466.0
HKD1_k127_3368304_20 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0009318 51.0
HKD1_k127_3368304_3 Glutathione S-transferase, C-terminal domain K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 381.0
HKD1_k127_3368304_4 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 394.0
HKD1_k127_3368304_5 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 352.0
HKD1_k127_3368304_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000816 262.0
HKD1_k127_3368304_7 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001457 259.0
HKD1_k127_3368304_8 Evidence 4 Homologs of previously reported genes of K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000203 251.0
HKD1_k127_3368304_9 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000008811 213.0
HKD1_k127_3389731_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 485.0
HKD1_k127_3389731_1 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 477.0
HKD1_k127_3389731_2 Domain of unknown function (DUF4188) - - - 0.00000000000000000000000000000000000000000000000000000002792 209.0
HKD1_k127_3389731_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000001286 189.0
HKD1_k127_3389731_4 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000007559 187.0
HKD1_k127_3389731_5 Belongs to the ompA family - - - 0.000000000000000000000000000000000008459 153.0
HKD1_k127_3389731_6 membrane - - - 0.00000000000000000000000000000001018 134.0
HKD1_k127_3389731_7 Cysteine-rich domain K11473 - - 0.00000000000000000000000000001214 130.0
HKD1_k127_3389731_8 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000542 128.0
HKD1_k127_3389731_9 WHG domain - - - 0.0000000000000000000009427 104.0
HKD1_k127_3392396_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 618.0
HKD1_k127_3392396_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 598.0
HKD1_k127_3392396_10 transport system, permease and ATPase K02471 - - 0.00000000000000000000000000000000000000000000000000001319 207.0
HKD1_k127_3392396_11 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000766 176.0
HKD1_k127_3392396_2 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 568.0
HKD1_k127_3392396_3 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 525.0
HKD1_k127_3392396_4 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 493.0
HKD1_k127_3392396_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 357.0
HKD1_k127_3392396_6 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 340.0
HKD1_k127_3392396_7 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 318.0
HKD1_k127_3392396_8 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 295.0
HKD1_k127_3392396_9 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000166 221.0
HKD1_k127_3411431_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.146e-302 948.0
HKD1_k127_3411431_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.839e-277 877.0
HKD1_k127_3411431_2 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 542.0
HKD1_k127_3411431_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 331.0
HKD1_k127_3411431_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001813 274.0
HKD1_k127_3411431_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000000000000000004802 105.0
HKD1_k127_3411431_6 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000525 105.0
HKD1_k127_3411431_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000004779 71.0
HKD1_k127_3411431_8 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000001906 64.0
HKD1_k127_3475282_0 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 389.0
HKD1_k127_3475282_1 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 316.0
HKD1_k127_3475282_2 COG2211 Na melibiose symporter and related K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000003503 263.0
HKD1_k127_3475282_3 endonuclease activity K07451 - - 0.000000000000000008986 91.0
HKD1_k127_3475282_4 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000004805 58.0
HKD1_k127_349969_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.845e-302 962.0
HKD1_k127_349969_1 DEAD DEAH box helicase K06877 - - 1.169e-290 932.0
HKD1_k127_349969_10 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001156 301.0
HKD1_k127_349969_11 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000136 268.0
HKD1_k127_349969_12 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000001502 260.0
HKD1_k127_349969_13 - - - - 0.0000000000000000000000000000000000000000000000000002019 200.0
HKD1_k127_349969_14 YMGG-like Gly-zipper - - - 0.0000000000000000000000000000000000000000004707 162.0
HKD1_k127_349969_15 ATPases associated with a variety of cellular activities K09820,K11603,K11607 - - 0.000000000000000000000000000000000000000002032 168.0
HKD1_k127_349969_16 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000005025 151.0
HKD1_k127_349969_17 - - - - 0.000000000000000000000001749 117.0
HKD1_k127_349969_18 Protein of unknown function (DUF1634) - - - 0.0000000000000000000005702 99.0
HKD1_k127_349969_19 Transcriptional regulator K13643 - - 0.0000000000000000003878 104.0
HKD1_k127_349969_2 elongation factor G domain IV K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 574.0
HKD1_k127_349969_20 Diguanylate cyclase - - - 0.00000000000001995 87.0
HKD1_k127_349969_21 WD40-like Beta Propeller Repeat - - - 0.000000000001033 79.0
HKD1_k127_349969_22 Putative diguanylate phosphodiesterase - - - 0.000000003898 70.0
HKD1_k127_349969_23 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000183 65.0
HKD1_k127_349969_24 cheY-homologous receiver domain - - - 0.000105 50.0
HKD1_k127_349969_3 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 513.0
HKD1_k127_349969_4 sulfate adenylyltransferase K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 470.0
HKD1_k127_349969_5 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 434.0
HKD1_k127_349969_6 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 408.0
HKD1_k127_349969_7 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 408.0
HKD1_k127_349969_8 Aminotransferase, class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 340.0
HKD1_k127_349969_9 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 314.0
HKD1_k127_351042_0 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 2.003e-198 650.0
HKD1_k127_351042_1 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 376.0
HKD1_k127_351042_10 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000003381 185.0
HKD1_k127_351042_11 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000001139 181.0
HKD1_k127_351042_12 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000004133 108.0
HKD1_k127_351042_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 357.0
HKD1_k127_351042_3 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 342.0
HKD1_k127_351042_4 RNA-3'-phosphate cyclase activity K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 314.0
HKD1_k127_351042_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 341.0
HKD1_k127_351042_6 Helix-hairpin-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 306.0
HKD1_k127_351042_7 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 295.0
HKD1_k127_351042_8 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3 0.0000000000000000000000000000000000000000000000000000000001594 221.0
HKD1_k127_351042_9 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000001733 224.0
HKD1_k127_3541036_0 Ferrous iron transport protein B C terminus K04759 - - 1.587e-195 628.0
HKD1_k127_3541036_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 448.0
HKD1_k127_3541036_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 325.0
HKD1_k127_3541036_3 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000001447 271.0
HKD1_k127_3541036_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000002322 222.0
HKD1_k127_3541036_5 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000002052 199.0
HKD1_k127_3541036_6 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.000000000000000000000000000000000001846 143.0
HKD1_k127_3541036_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000001124 146.0
HKD1_k127_3541036_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 0.000000000000003588 85.0
HKD1_k127_3541036_9 COG1918 Fe2 transport system protein A K04758 - - 0.00000000000000881 77.0
HKD1_k127_3588573_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 580.0
HKD1_k127_3588573_1 dna topoisomerase III K03169 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 477.0
HKD1_k127_3588573_10 Sh3 type 3 domain protein - - - 0.000000000000000001037 103.0
HKD1_k127_3588573_11 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.000000000000000002199 91.0
HKD1_k127_3588573_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000268 90.0
HKD1_k127_3588573_13 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000004955 87.0
HKD1_k127_3588573_14 Sh3 type 3 domain protein - - - 0.0000000000001082 86.0
HKD1_k127_3588573_15 Sh3 type 3 domain protein - - - 0.0000000000001423 85.0
HKD1_k127_3588573_16 Sh3 type 3 domain protein - - - 0.0000000007278 73.0
HKD1_k127_3588573_17 Protein of unknown function (DUF1329) - - - 0.0000115 58.0
HKD1_k127_3588573_2 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 431.0
HKD1_k127_3588573_3 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 428.0
HKD1_k127_3588573_4 Dehydrogenase E1 component K21416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 394.0
HKD1_k127_3588573_5 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 333.0
HKD1_k127_3588573_6 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000000000002646 235.0
HKD1_k127_3588573_7 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000002758 239.0
HKD1_k127_3588573_8 PAC2 family - - - 0.00000000000000000000000000000000000000000000000000000000001406 224.0
HKD1_k127_3588573_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000003499 213.0
HKD1_k127_3605424_0 Amino acid adenylation domain protein - - - 0.0 1105.0
HKD1_k127_3605424_1 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0 1090.0
HKD1_k127_3605424_2 AMP-binding enzyme C-terminal domain K04780 - - 0.000000000000000000000000000000000000000000006648 171.0
HKD1_k127_3656898_0 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000008177 232.0
HKD1_k127_3656898_1 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000009812 197.0
HKD1_k127_3656898_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000655 136.0
HKD1_k127_3785688_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 5.749e-201 654.0
HKD1_k127_3785688_1 PFAM class II aldolase adducin family protein - - - 9.958e-198 639.0
HKD1_k127_3785688_10 PFAM Alpha beta hydrolase fold-3 domain protein K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 387.0
HKD1_k127_3785688_11 Potential Queuosine, Q, salvage protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 332.0
HKD1_k127_3785688_12 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 327.0
HKD1_k127_3785688_13 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 312.0
HKD1_k127_3785688_14 Bacterial periplasmic substrate-binding proteins K01713 - 4.2.1.51,4.2.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 302.0
HKD1_k127_3785688_15 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 300.0
HKD1_k127_3785688_16 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006565 279.0
HKD1_k127_3785688_17 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000734 270.0
HKD1_k127_3785688_18 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008163 269.0
HKD1_k127_3785688_19 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000007628 247.0
HKD1_k127_3785688_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K18688 - 6.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 590.0
HKD1_k127_3785688_20 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000006265 250.0
HKD1_k127_3785688_21 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000007849 246.0
HKD1_k127_3785688_22 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000003062 229.0
HKD1_k127_3785688_23 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000001987 212.0
HKD1_k127_3785688_24 Thioesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000000000000000000000001369 192.0
HKD1_k127_3785688_25 protein conserved in bacteria K09922 - - 0.0000000000000000000000000000000000000000000000002868 180.0
HKD1_k127_3785688_26 Adenosine/AMP deaminase - - - 0.000000000000000000000000000000000000000000000001285 186.0
HKD1_k127_3785688_27 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000273 181.0
HKD1_k127_3785688_28 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000001226 174.0
HKD1_k127_3785688_29 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000002947 171.0
HKD1_k127_3785688_3 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 579.0
HKD1_k127_3785688_30 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000001499 173.0
HKD1_k127_3785688_31 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000000833 170.0
HKD1_k127_3785688_32 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07281,K07291 - 2.7.7.74,2.7.8.34 0.0000000000000000000000000000000000000002534 166.0
HKD1_k127_3785688_33 NUDIX domain - - - 0.00000000000000000000000000000000000001416 155.0
HKD1_k127_3785688_34 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000004824 155.0
HKD1_k127_3785688_35 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000008556 147.0
HKD1_k127_3785688_36 PAS PAC sensor signal transduction histidine kinase K19661 - 2.7.13.3 0.0000000000000000000000000000000007446 149.0
HKD1_k127_3785688_37 - - - - 0.0000000000000000000000000000006736 136.0
HKD1_k127_3785688_38 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - 0.0000000000000000000000000001793 134.0
HKD1_k127_3785688_39 Belongs to the Fur family K09825 - - 0.00000000000000000000000000638 118.0
HKD1_k127_3785688_4 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 560.0
HKD1_k127_3785688_40 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000669 128.0
HKD1_k127_3785688_41 ACT domain - - - 0.00000000000000000000001878 106.0
HKD1_k127_3785688_42 - - - - 0.00000000000000000000002997 102.0
HKD1_k127_3785688_43 - - - - 0.000000000000000000003564 94.0
HKD1_k127_3785688_44 Pas domain K03320,K11525 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000004906 101.0
HKD1_k127_3785688_45 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000006648 93.0
HKD1_k127_3785688_46 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000001044 99.0
HKD1_k127_3785688_48 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.0000000000000003933 89.0
HKD1_k127_3785688_49 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000004664 79.0
HKD1_k127_3785688_5 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 520.0
HKD1_k127_3785688_51 - - - - 0.0000000000009361 75.0
HKD1_k127_3785688_52 Responsible for synthesis of pseudouridine from uracil K06179,K06180 - 5.4.99.23,5.4.99.24 0.00000000001862 76.0
HKD1_k127_3785688_53 Pfam:DUF385 - - - 0.0000000002332 67.0
HKD1_k127_3785688_54 SNARE associated Golgi protein - - - 0.000000005018 66.0
HKD1_k127_3785688_55 Cold shock K03704 - - 0.00000001406 63.0
HKD1_k127_3785688_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 460.0
HKD1_k127_3785688_7 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 439.0
HKD1_k127_3785688_8 calcium:proton antiporter activity K07300 GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035725,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 422.0
HKD1_k127_3785688_9 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 400.0
HKD1_k127_3799438_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 500.0
HKD1_k127_3799438_1 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007771 302.0
HKD1_k127_3799438_2 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K00917 - 2.7.1.144 0.0000000000000000000000000000000000005547 153.0
HKD1_k127_3799438_3 4 iron, 4 sulfur cluster binding K05524 GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - 0.0000000000000000000000000000000003387 134.0
HKD1_k127_3799438_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000116 110.0
HKD1_k127_3799438_5 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000149 95.0
HKD1_k127_3799438_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000009013 91.0
HKD1_k127_3844128_0 Mate efflux family protein K03327 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006862,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015215,GO:0015230,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034220,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042886,GO:0042887,GO:0042938,GO:0044464,GO:0044610,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 368.0
HKD1_k127_3844128_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001701 299.0
HKD1_k127_3844128_2 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000003558 231.0
HKD1_k127_3844128_3 CBS domain K04767,K07168,K07182 - - 0.0000000000000000000000000000005217 127.0
HKD1_k127_3844128_4 Universal stress protein - - - 0.000000000000000004291 96.0
HKD1_k127_3844128_5 - - - - 0.0000000006494 66.0
HKD1_k127_385107_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 5.077e-199 660.0
HKD1_k127_385107_1 Cupin domain - - - 0.000000000000000000000000000000000000000000000000003203 185.0
HKD1_k127_385107_2 - - - - 0.00000000000000000001422 100.0
HKD1_k127_385107_3 - - - - 0.00000000001337 65.0
HKD1_k127_3868477_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 480.0
HKD1_k127_3868477_1 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 312.0
HKD1_k127_3868477_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 306.0
HKD1_k127_3868477_3 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001823 236.0
HKD1_k127_3868477_4 pfam ammecr1 K09141 - - 0.000000000000000000000000000000000000000000005419 173.0
HKD1_k127_3868477_6 arylsulfatase A - - - 0.00000000000000000000000000008667 134.0
HKD1_k127_3868477_7 E-Z type HEAT repeats - - - 0.00005877 55.0
HKD1_k127_3900548_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 459.0
HKD1_k127_3900548_1 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003646 283.0
HKD1_k127_3900548_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007824 266.0
HKD1_k127_3900548_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000001163 197.0
HKD1_k127_3900548_4 - - - - 0.00000000000000000000000000000000000000001412 174.0
HKD1_k127_3900548_5 Limonene-1,2-epoxide hydrolase catalytic domain K10533 - 3.3.2.8 0.0000000000000000000000000008647 121.0
HKD1_k127_3900548_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000004865 105.0
HKD1_k127_3900548_7 Type IV pilin PilA K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0000000000006127 77.0
HKD1_k127_3901301_0 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 412.0
HKD1_k127_3901301_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 396.0
HKD1_k127_3901301_2 Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively K00032,K00090,K18916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008873,GO:0008875,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0019520,GO:0019522,GO:0019752,GO:0030267,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046181,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.215,1.1.1.43,1.1.1.79,1.1.1.81,1.20.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 383.0
HKD1_k127_3901301_3 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 364.0
HKD1_k127_3901301_4 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 310.0
HKD1_k127_3901301_5 YacP-like NYN domain - - - 0.00005549 53.0
HKD1_k127_3976223_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.143e-263 835.0
HKD1_k127_3976223_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 454.0
HKD1_k127_3976223_10 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000684 108.0
HKD1_k127_3976223_11 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000001186 104.0
HKD1_k127_3976223_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000001008 91.0
HKD1_k127_3976223_13 Preprotein translocase, subunit SecG K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000001586 98.0
HKD1_k127_3976223_14 DSBA-like thioredoxin domain - - - 0.00000000000000003308 94.0
HKD1_k127_3976223_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 407.0
HKD1_k127_3976223_3 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 357.0
HKD1_k127_3976223_4 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 327.0
HKD1_k127_3976223_5 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008993 305.0
HKD1_k127_3976223_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 291.0
HKD1_k127_3976223_7 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006135 260.0
HKD1_k127_3976223_8 PFAM Flavin - - - 0.000000000000000000000000000000000003681 146.0
HKD1_k127_3976223_9 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000001331 145.0
HKD1_k127_3979387_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1030.0
HKD1_k127_3979387_1 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 417.0
HKD1_k127_3979387_2 Binding-protein-dependent transport system inner membrane component K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 394.0
HKD1_k127_3979387_3 sulfate transport system, permease K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000001757 239.0
HKD1_k127_3979387_4 Kinase/pyrophosphorylase K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000005031 242.0
HKD1_k127_4028396_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 359.0
HKD1_k127_4028396_1 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000002264 156.0
HKD1_k127_4028396_2 Enoyl-CoA hydratase/isomerase K01692,K13766 - 4.2.1.17,4.2.1.18 0.0000000000000002346 82.0
HKD1_k127_4028396_3 PFAM Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000004222 76.0
HKD1_k127_4036846_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 6.082e-284 909.0
HKD1_k127_4036846_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 357.0
HKD1_k127_4036846_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002872 276.0
HKD1_k127_4036846_3 SURF1-like protein K14998 - - 0.00000000000000000000002448 112.0
HKD1_k127_4036846_4 - - - - 0.0000000000002496 78.0
HKD1_k127_4041133_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 536.0
HKD1_k127_4041133_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 340.0
HKD1_k127_4041133_2 'glutamate synthase K00123,K00317,K00528,K09835 - 1.17.1.9,1.18.1.2,1.19.1.1,1.5.8.1,1.5.8.2,5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 325.0
HKD1_k127_4041133_3 Sugar efflux transporter for intercellular exchange - - - 0.000000000000000000000000001823 112.0
HKD1_k127_404425_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 355.0
HKD1_k127_404425_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 327.0
HKD1_k127_404425_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 296.0
HKD1_k127_4068647_0 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 421.0
HKD1_k127_4068647_1 GMC oxidoreductase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000003188 235.0
HKD1_k127_4094578_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0 1243.0
HKD1_k127_4094578_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 5.853e-207 651.0
HKD1_k127_4094578_10 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 305.0
HKD1_k127_4094578_11 Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities K01524 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006797,GO:0006798,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009056,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360,GO:1901575 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 295.0
HKD1_k127_4094578_12 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002166 259.0
HKD1_k127_4094578_13 Protein of unknown function (DUF541) K09797 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002677 252.0
HKD1_k127_4094578_14 Domain of unknown function (DUF4336) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006915 235.0
HKD1_k127_4094578_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000742 247.0
HKD1_k127_4094578_16 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000001751 229.0
HKD1_k127_4094578_17 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000001842 239.0
HKD1_k127_4094578_18 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000005208 203.0
HKD1_k127_4094578_19 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000001553 196.0
HKD1_k127_4094578_2 6-phosphogluconate dehydrogenase (decarboxylating) K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 498.0
HKD1_k127_4094578_20 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000007008 196.0
HKD1_k127_4094578_21 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000001107 200.0
HKD1_k127_4094578_23 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000000000005619 178.0
HKD1_k127_4094578_24 RNHCP domain - - - 0.000000000000000000000000000000000000000002333 164.0
HKD1_k127_4094578_25 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000001109 157.0
HKD1_k127_4094578_26 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000001915 163.0
HKD1_k127_4094578_27 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000002318 154.0
HKD1_k127_4094578_28 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.0000000000000000000000000000000000004295 149.0
HKD1_k127_4094578_29 Acetyltransferase - - - 0.0000000000000000000000000000000000009402 145.0
HKD1_k127_4094578_3 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 504.0
HKD1_k127_4094578_30 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000008701 153.0
HKD1_k127_4094578_31 Domain of unknown function (DUF4184) - - - 0.0000000000000000000000000000000001422 148.0
HKD1_k127_4094578_32 - - - - 0.00000000000000000000000000000006757 131.0
HKD1_k127_4094578_33 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000001497 127.0
HKD1_k127_4094578_34 3D domain protein - - - 0.0000000000000000000000000002195 128.0
HKD1_k127_4094578_35 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000001721 121.0
HKD1_k127_4094578_36 CHAD domain containing protein - - - 0.0000000000000000000000009463 121.0
HKD1_k127_4094578_37 COG1246 N-acetylglutamate synthase and related acetyltransferases K00619 - 2.3.1.1 0.0000000000000000000001626 108.0
HKD1_k127_4094578_38 Universal stress protein family - - - 0.0000000000000000000001626 108.0
HKD1_k127_4094578_4 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 491.0
HKD1_k127_4094578_40 Membrane - - - 0.00000000000006308 81.0
HKD1_k127_4094578_41 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000009022 79.0
HKD1_k127_4094578_42 -acetyltransferase K03828,K17840 - 2.3.1.59 0.000000000007137 76.0
HKD1_k127_4094578_44 Protein of unknown function (DUF3106) - - - 0.00002085 55.0
HKD1_k127_4094578_45 CHAT domain - - - 0.00002511 55.0
HKD1_k127_4094578_5 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 402.0
HKD1_k127_4094578_6 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 374.0
HKD1_k127_4094578_7 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 362.0
HKD1_k127_4094578_8 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 346.0
HKD1_k127_4094578_9 Peptidase family S49 K04773,K04774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 329.0
HKD1_k127_4120032_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 6.857e-273 850.0
HKD1_k127_4120032_1 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001952 288.0
HKD1_k127_4120032_2 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007718 267.0
HKD1_k127_4120032_3 Belongs to the peptidase S8 family K01361 - 3.4.21.96 0.0000000000000000000000000000000000000000000000000000000000002269 235.0
HKD1_k127_4120032_5 - - - - 0.0000000000000000000000002092 115.0
HKD1_k127_4120032_7 Sigma-70, region 4 K03088 - - 0.00000000000108 78.0
HKD1_k127_4122592_0 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 308.0
HKD1_k127_4122592_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 299.0
HKD1_k127_4122592_2 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001307 278.0
HKD1_k127_4122592_3 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.00000000000000000000000000000000124 149.0
HKD1_k127_4122592_4 Chemotaxis protein CheC, inhibitor of MCP K03410 - - 0.00000000000000006487 91.0
HKD1_k127_4122592_5 Histidine Phosphotransfer domain K03407 - 2.7.13.3 0.00003034 49.0
HKD1_k127_4189585_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 368.0
HKD1_k127_4190869_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 3.57e-244 769.0
HKD1_k127_4190869_1 CoA binding domain - - - 5.642e-227 721.0
HKD1_k127_4190869_2 Binding-protein-dependent transport system inner membrane component K02050 - - 1.002e-201 652.0
HKD1_k127_4190869_3 C-terminal AAA-associated domain K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 541.0
HKD1_k127_4190869_4 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 415.0
HKD1_k127_4190869_5 DNA topoisomerase III K03169 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000003593 212.0
HKD1_k127_4190869_6 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.000000000000000000000000000000000000000000000000000001374 201.0
HKD1_k127_4190869_7 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000001991 186.0
HKD1_k127_4190869_8 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000001139 155.0
HKD1_k127_4190869_9 6-phosphogluconolactonase activity - - - 0.00000000329 69.0
HKD1_k127_4209808_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.08e-216 693.0
HKD1_k127_4209808_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.048e-201 651.0
HKD1_k127_4209808_10 - - - - 0.00000000000000000000000000000000000345 151.0
HKD1_k127_4209808_11 HAD-superfamily hydrolase, subfamily IB, PSPase-like K08966 - 3.1.3.87 0.00000000000000000000006679 116.0
HKD1_k127_4209808_12 SMART Tetratricopeptide - - - 0.00000000000005005 85.0
HKD1_k127_4209808_13 Methyltransferase domain - - - 0.0000000001986 72.0
HKD1_k127_4209808_14 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.000000002506 71.0
HKD1_k127_4209808_15 peptidyl-tyrosine sulfation - - - 0.0001004 55.0
HKD1_k127_4209808_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 573.0
HKD1_k127_4209808_3 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 481.0
HKD1_k127_4209808_4 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 445.0
HKD1_k127_4209808_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 394.0
HKD1_k127_4209808_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 369.0
HKD1_k127_4209808_7 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000004345 274.0
HKD1_k127_4209808_8 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000003125 244.0
HKD1_k127_4209808_9 Homocysteine S-methyltransferase K00547,K21169 - 2.1.1.10 0.00000000000000000000000000000000000000000000000000000002349 213.0
HKD1_k127_4274083_0 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 535.0
HKD1_k127_4274083_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 347.0
HKD1_k127_4274083_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 327.0
HKD1_k127_4274083_3 PFAM Ribonuclease BN-like family K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002426 283.0
HKD1_k127_4274083_4 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000003864 213.0
HKD1_k127_4274083_5 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067,K06192 - - 0.0000000000000000000000000000000000000000000000001544 204.0
HKD1_k127_4274083_6 Protein conserved in bacteria K18480 - - 0.000000000000000000000000000000009974 145.0
HKD1_k127_4274083_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0007461 50.0
HKD1_k127_4305116_0 Belongs to the ClpA ClpB family K11907 - - 5.215e-280 890.0
HKD1_k127_4305116_1 protein conserved in bacteria K11900 - - 5.498e-222 698.0
HKD1_k127_4305116_10 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003126 273.0
HKD1_k127_4305116_11 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002576 264.0
HKD1_k127_4305116_12 Type VI secretion system effector, Hcp K11903 - - 0.00000000000000000000000000000000000000000000000000000000000000001856 229.0
HKD1_k127_4305116_13 synthase K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000007096 233.0
HKD1_k127_4305116_14 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000592 214.0
HKD1_k127_4305116_15 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000001526 209.0
HKD1_k127_4305116_16 ImcF-related N-terminal domain K11891 - - 0.00000000000000000000000000000000000000000000000000001108 217.0
HKD1_k127_4305116_17 Type VI secretion, TssG K11895 - - 0.00000000000000000000000000000000000000000000000002808 206.0
HKD1_k127_4305116_18 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.0000000000000000000000000000000000000000000000002288 194.0
HKD1_k127_4305116_19 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000003595 199.0
HKD1_k127_4305116_2 protein conserved in bacteria K11904 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 604.0
HKD1_k127_4305116_20 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.00000000000000000000000000000000000000000000000957 189.0
HKD1_k127_4305116_21 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000006734 180.0
HKD1_k127_4305116_22 Domain of unknown function (DUF4150) - - - 0.0000000000000000000000000000000000000000007721 173.0
HKD1_k127_4305116_23 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ K11910 - - 0.00000000000000000000000000000000000005339 154.0
HKD1_k127_4305116_24 TIGRFAM type VI secretion protein, EvpB VC_A0108 family - - - 0.00000000000000000000000000000000001546 154.0
HKD1_k127_4305116_25 - - - - 0.000000000000000000000000000000199 136.0
HKD1_k127_4305116_26 - - - - 0.000000000000000000000000000001244 130.0
HKD1_k127_4305116_27 Transglycosylase SLT domain K08307 - - 0.000000000000000000000000008423 128.0
HKD1_k127_4305116_28 - - - - 0.00000000000000000000004061 111.0
HKD1_k127_4305116_29 TIGRFAM Type VI secretion system, lysozyme-related K11905 - - 0.000000000000000000264 94.0
HKD1_k127_4305116_3 protein conserved in bacteria K11896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007235 484.0
HKD1_k127_4305116_30 Protein of unknown function (DUF2914) - - - 0.0000000000000003574 94.0
HKD1_k127_4305116_31 Type VI secretion system protein DotU K11892 - - 0.00000000000003508 81.0
HKD1_k127_4305116_32 lyase activity - - - 0.000000000000406 82.0
HKD1_k127_4305116_33 involved in transcriptional mechanism. thought to regulate the biosynthesis of the mycobacterial cell wall arabinan and resistance to ethambutol (Emb - - - 0.000000003868 71.0
HKD1_k127_4305116_34 - - - - 0.00000002409 61.0
HKD1_k127_4305116_35 Forkhead associated domain - - - 0.0000000504 63.0
HKD1_k127_4305116_36 Polysaccharide deacetylase - - - 0.000004438 59.0
HKD1_k127_4305116_37 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 K11906 - - 0.0002845 51.0
HKD1_k127_4305116_38 Protein of unknown function (DUF3187) - - - 0.0004141 53.0
HKD1_k127_4305116_4 COG0277 FAD FMN-containing dehydrogenases K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 442.0
HKD1_k127_4305116_5 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 391.0
HKD1_k127_4305116_6 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 382.0
HKD1_k127_4305116_7 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 362.0
HKD1_k127_4305116_8 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 300.0
HKD1_k127_4305116_9 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 304.0
HKD1_k127_4320645_0 DNA helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 418.0
HKD1_k127_4320645_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000008278 251.0
HKD1_k127_4320645_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000005522 214.0
HKD1_k127_4320645_3 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000004833 191.0
HKD1_k127_4320645_4 MlaD protein K02067 - - 0.00000000000000000000000000000002548 132.0
HKD1_k127_4320645_5 toluene tolerance family protein K07323 - - 0.00000000000000000000000004965 117.0
HKD1_k127_4320645_6 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.0000000006001 70.0
HKD1_k127_4320645_7 PD-(D/E)XK nuclease superfamily - - - 0.000008155 60.0
HKD1_k127_4341202_0 HpcH/HpaI aldolase/citrate lyase family K08691 - 4.1.3.24,4.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 520.0
HKD1_k127_4341202_1 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 474.0
HKD1_k127_4341202_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 381.0
HKD1_k127_4399612_0 DEAD DEAH box K03724 - - 0.0 1845.0
HKD1_k127_4399612_1 TIGRFAM alpha-glucan - - - 2.626e-300 944.0
HKD1_k127_4399612_10 Acetyltransferase (GNAT) domain - - - 0.0000000007386 68.0
HKD1_k127_4399612_2 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 426.0
HKD1_k127_4399612_3 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 374.0
HKD1_k127_4399612_4 AsmA family K07289,K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008563 261.0
HKD1_k127_4399612_5 Phosphate K02040 - - 0.000000000000000000000000000000000000000000000000000000002483 214.0
HKD1_k127_4399612_6 Subtilase family - - - 0.00000000000000000000000000000000000000000008133 181.0
HKD1_k127_4399612_7 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000002979 149.0
HKD1_k127_4399612_8 PFAM CAAX amino terminal protease family K07052 - - 0.000000000000001401 87.0
HKD1_k127_4399612_9 Acylphosphatase K01512 - 3.6.1.7 0.0000000000003698 73.0
HKD1_k127_4403699_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 8.125e-212 676.0
HKD1_k127_4403699_1 AMP-binding enzyme K02182 - 6.2.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 623.0
HKD1_k127_4403699_10 phosphotriesterase homology protein K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 334.0
HKD1_k127_4403699_11 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002847 278.0
HKD1_k127_4403699_12 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008035 271.0
HKD1_k127_4403699_13 Alcohol dehydrogenase GroES-like domain K00121,K00148 - 1.1.1.1,1.1.1.284,1.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000007015 283.0
HKD1_k127_4403699_14 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000003708 245.0
HKD1_k127_4403699_15 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000006717 225.0
HKD1_k127_4403699_16 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000003374 166.0
HKD1_k127_4403699_17 Protein of unknown function (DUF3237) - - - 0.00000000000000000000000000000000000000000000929 168.0
HKD1_k127_4403699_18 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000000000001151 186.0
HKD1_k127_4403699_19 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000971 167.0
HKD1_k127_4403699_2 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 501.0
HKD1_k127_4403699_20 EthD domain - - - 0.00000000000000000000000000000000001232 145.0
HKD1_k127_4403699_21 - - - - 0.00000000000000000000000000000000006679 141.0
HKD1_k127_4403699_22 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000002617 154.0
HKD1_k127_4403699_24 oxidoreductase activity K02674,K07114 - - 0.00000000000000000000000000004832 131.0
HKD1_k127_4403699_25 Protein of unknown function (DUF1329) - - - 0.0000000000000000000000002123 121.0
HKD1_k127_4403699_26 Glycosyl hydrolase - - - 0.000000000000000765 91.0
HKD1_k127_4403699_27 MMPL family - - - 0.00000000000001837 82.0
HKD1_k127_4403699_3 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 444.0
HKD1_k127_4403699_4 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 406.0
HKD1_k127_4403699_5 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 432.0
HKD1_k127_4403699_6 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 422.0
HKD1_k127_4403699_7 PFAM Transketolase central region K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 351.0
HKD1_k127_4403699_8 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 334.0
HKD1_k127_4403699_9 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 330.0
HKD1_k127_4444122_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 3.331e-272 853.0
HKD1_k127_4444122_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 478.0
HKD1_k127_4444122_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 409.0
HKD1_k127_4444122_3 ATP synthase A chain - - - 0.0000000000000000000000000000000000000000000003406 174.0
HKD1_k127_4444122_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000002215 93.0
HKD1_k127_4444122_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000004251 65.0
HKD1_k127_4444122_6 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000006094 62.0
HKD1_k127_4444122_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000191 61.0
HKD1_k127_4481120_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.8e-223 714.0
HKD1_k127_4481120_1 Malic enzyme, N-terminal domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 407.0
HKD1_k127_4481120_2 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 289.0
HKD1_k127_4522016_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 3.759e-298 947.0
HKD1_k127_4522016_1 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 2.437e-266 845.0
HKD1_k127_4522016_10 Bacterial regulatory proteins, tetR family - - - 0.00000008511 62.0
HKD1_k127_4522016_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 380.0
HKD1_k127_4522016_3 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 350.0
HKD1_k127_4522016_4 Putative methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001734 204.0
HKD1_k127_4522016_5 Mate efflux family protein K03327 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006862,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015215,GO:0015230,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034220,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042886,GO:0042887,GO:0042938,GO:0044464,GO:0044610,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1904680 - 0.00000000000000000000000000000000000000000000000000003365 206.0
HKD1_k127_4522016_6 TraB family K09973 - - 0.000000000000000000000000000000000000000003707 173.0
HKD1_k127_4522016_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000004869 156.0
HKD1_k127_4522016_8 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000009421 141.0
HKD1_k127_4522016_9 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000002686 109.0
HKD1_k127_457105_0 glycosyl transferase family K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 6.872e-293 918.0
HKD1_k127_457105_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 1.502e-262 820.0
HKD1_k127_457105_2 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 485.0
HKD1_k127_457105_3 cytochrome p450 K16046 - 1.14.13.221 0.00000000000000000000000000000000008677 135.0
HKD1_k127_457105_4 Ketosteroid isomerase-related protein - - - 0.0002847 51.0
HKD1_k127_4622459_0 FtsX-like permease family K02004 - - 4.088e-244 825.0
HKD1_k127_4622459_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 5.879e-240 755.0
HKD1_k127_4622459_10 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 483.0
HKD1_k127_4622459_11 DNA recombination protein RmuC K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 451.0
HKD1_k127_4622459_12 Belongs to the class-I aminoacyl-tRNA synthetase family K01885,K01894 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 390.0
HKD1_k127_4622459_13 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 362.0
HKD1_k127_4622459_14 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 353.0
HKD1_k127_4622459_15 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 346.0
HKD1_k127_4622459_16 Helix-turn-helix domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 345.0
HKD1_k127_4622459_17 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 337.0
HKD1_k127_4622459_18 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 323.0
HKD1_k127_4622459_19 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 318.0
HKD1_k127_4622459_2 Carboxyl transferase domain - - - 6.223e-235 753.0
HKD1_k127_4622459_20 PFAM Enoyl-CoA hydratase isomerase K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 317.0
HKD1_k127_4622459_21 Fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 318.0
HKD1_k127_4622459_22 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 317.0
HKD1_k127_4622459_23 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 299.0
HKD1_k127_4622459_24 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000136 286.0
HKD1_k127_4622459_25 PFAM glutamine amidotransferase class-I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001306 265.0
HKD1_k127_4622459_26 TIGRFAM carbohydrate kinase, thermoresistant glucokinase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001627 277.0
HKD1_k127_4622459_27 LamB/YcsF family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001321 255.0
HKD1_k127_4622459_28 KR domain K00039 - 1.1.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000003484 255.0
HKD1_k127_4622459_29 Carboxyltransferase domain, subdomain A and B - - - 0.0000000000000000000000000000000000000000000000000000000000000000001283 258.0
HKD1_k127_4622459_3 Molybdopterin oxidoreductase Fe4S4 domain - - - 2.725e-215 691.0
HKD1_k127_4622459_30 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000002796 206.0
HKD1_k127_4622459_31 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000003823 196.0
HKD1_k127_4622459_32 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000002102 174.0
HKD1_k127_4622459_33 LamB/YcsF family K07160 - - 0.000000000000000000000000000000000000000000004116 185.0
HKD1_k127_4622459_34 Lipoate-protein ligase - - - 0.0000000000000000000000000000000000000001867 167.0
HKD1_k127_4622459_35 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000002018 127.0
HKD1_k127_4622459_36 phosphatase activity K07025 - - 0.000000000000000000000000000008318 128.0
HKD1_k127_4622459_37 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000005048 129.0
HKD1_k127_4622459_38 rRNA binding K02909 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001593 106.0
HKD1_k127_4622459_39 - - - - 0.00000000000000000000116 103.0
HKD1_k127_4622459_4 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 580.0
HKD1_k127_4622459_40 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000003819 100.0
HKD1_k127_4622459_41 EamA-like transporter family - - - 0.000000000000003837 87.0
HKD1_k127_4622459_42 Domain of unknown function DUF11 - - - 0.000000000000004976 85.0
HKD1_k127_4622459_43 6-phosphogluconolactonase activity - - - 0.0000000000007934 72.0
HKD1_k127_4622459_44 - - - - 0.0000000008167 68.0
HKD1_k127_4622459_46 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.00000006208 62.0
HKD1_k127_4622459_5 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 573.0
HKD1_k127_4622459_6 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 584.0
HKD1_k127_4622459_7 Belongs to the heat shock protein 70 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 544.0
HKD1_k127_4622459_8 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 546.0
HKD1_k127_4622459_9 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 477.0
HKD1_k127_4631201_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.949e-297 938.0
HKD1_k127_4631201_1 FeS assembly protein SufB K09014 - - 1.057e-253 788.0
HKD1_k127_4631201_10 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 374.0
HKD1_k127_4631201_11 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 372.0
HKD1_k127_4631201_12 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 335.0
HKD1_k127_4631201_13 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 341.0
HKD1_k127_4631201_14 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000247 235.0
HKD1_k127_4631201_15 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000007098 239.0
HKD1_k127_4631201_16 Squalene/phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000000000000007208 229.0
HKD1_k127_4631201_17 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000185 235.0
HKD1_k127_4631201_18 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000004873 213.0
HKD1_k127_4631201_19 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000003793 194.0
HKD1_k127_4631201_2 Amidohydrolase family - - - 5.138e-220 695.0
HKD1_k127_4631201_20 Transcriptional regulator K13771 - - 0.00000000000000000000000000000000000000001977 158.0
HKD1_k127_4631201_21 Pfam:DUF59 K02612 - - 0.00000000000000000000000000000000000001051 148.0
HKD1_k127_4631201_22 Transcriptional regulator - - - 0.0000000000000000000000000000000000003958 146.0
HKD1_k127_4631201_23 arsenate reductase K00537 - 1.20.4.1 0.00000000000000000000000000009856 119.0
HKD1_k127_4631201_24 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000001006 128.0
HKD1_k127_4631201_25 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000155 133.0
HKD1_k127_4631201_26 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000008024 105.0
HKD1_k127_4631201_27 tetR family - - - 0.0000000000000000007257 98.0
HKD1_k127_4631201_28 Bacterial transcriptional repressor C-terminal - - - 0.00000000000000004556 92.0
HKD1_k127_4631201_29 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000009654 92.0
HKD1_k127_4631201_3 Belongs to the RtcB family K14415 - 6.5.1.3 1.702e-204 647.0
HKD1_k127_4631201_30 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000004208 78.0
HKD1_k127_4631201_31 Major Facilitator Superfamily - - - 0.00000000002077 76.0
HKD1_k127_4631201_4 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 591.0
HKD1_k127_4631201_5 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 534.0
HKD1_k127_4631201_6 Squalene-hopene cyclase C-terminal domain K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 436.0
HKD1_k127_4631201_7 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 442.0
HKD1_k127_4631201_8 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 426.0
HKD1_k127_4631201_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 391.0
HKD1_k127_4635080_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 334.0
HKD1_k127_4635080_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002535 286.0
HKD1_k127_4635080_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000001284 231.0
HKD1_k127_4657364_0 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 365.0
HKD1_k127_4657364_1 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 308.0
HKD1_k127_4657364_2 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001461 294.0
HKD1_k127_4657364_3 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007134 283.0
HKD1_k127_4657364_4 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006264 258.0
HKD1_k127_4668015_0 Elongation factor G C-terminus K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 1.394e-209 667.0
HKD1_k127_4668015_1 TrkA-C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 563.0
HKD1_k127_4668015_10 Fad dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 319.0
HKD1_k127_4668015_11 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 299.0
HKD1_k127_4668015_12 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004197 287.0
HKD1_k127_4668015_13 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000003497 207.0
HKD1_k127_4668015_14 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000006529 224.0
HKD1_k127_4668015_15 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000009907 222.0
HKD1_k127_4668015_16 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000006236 191.0
HKD1_k127_4668015_17 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000008325 198.0
HKD1_k127_4668015_18 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000004348 196.0
HKD1_k127_4668015_19 Belongs to the acetyltransferase family. ArgA subfamily K00537,K00619 - 1.20.4.1,2.3.1.1 0.0000000000000000000000000000000000000000000001122 183.0
HKD1_k127_4668015_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 390.0
HKD1_k127_4668015_20 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.00000000000000000000000000000000000000002949 168.0
HKD1_k127_4668015_21 Ferredoxin - - - 0.0000000000000000000000000000000000000001059 155.0
HKD1_k127_4668015_22 E3 Ubiquitin ligase - - - 0.000000000000000000000000000000000145 146.0
HKD1_k127_4668015_23 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000652 136.0
HKD1_k127_4668015_24 Phytanoyl-CoA dioxygenase (PhyH) K10674 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.14.11.55 0.00000000000000000000000000000001924 136.0
HKD1_k127_4668015_25 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000002271 123.0
HKD1_k127_4668015_26 recA bacterial DNA recombination protein - - - 0.000000000000000001345 98.0
HKD1_k127_4668015_27 HxlR-like helix-turn-helix - - - 0.00000000000000006777 90.0
HKD1_k127_4668015_28 His Kinase A (phosphoacceptor) domain - - - 0.00000002036 64.0
HKD1_k127_4668015_29 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000004759 63.0
HKD1_k127_4668015_3 pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 353.0
HKD1_k127_4668015_30 COG0760 Parvulin-like peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.000006113 59.0
HKD1_k127_4668015_31 PilZ domain - - - 0.000009895 55.0
HKD1_k127_4668015_32 - - - - 0.00001963 56.0
HKD1_k127_4668015_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 352.0
HKD1_k127_4668015_5 acyl-CoA dehydrogenase K06446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 346.0
HKD1_k127_4668015_6 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 348.0
HKD1_k127_4668015_7 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 349.0
HKD1_k127_4668015_8 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 331.0
HKD1_k127_4668015_9 fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 326.0
HKD1_k127_4696822_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0 1048.0
HKD1_k127_4696822_1 cytochrome C peroxidase - - - 2.753e-317 987.0
HKD1_k127_4696822_10 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 376.0
HKD1_k127_4696822_11 - K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 374.0
HKD1_k127_4696822_12 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 298.0
HKD1_k127_4696822_13 uracil-DNA glycosylase K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 287.0
HKD1_k127_4696822_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000023 288.0
HKD1_k127_4696822_15 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006897 301.0
HKD1_k127_4696822_16 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004732 278.0
HKD1_k127_4696822_17 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005587 258.0
HKD1_k127_4696822_18 PFAM Paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002255 259.0
HKD1_k127_4696822_19 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000002679 257.0
HKD1_k127_4696822_2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 6.103e-215 696.0
HKD1_k127_4696822_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003737 256.0
HKD1_k127_4696822_21 Methylamine dehydrogenase light chain K15228 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000001904 235.0
HKD1_k127_4696822_22 ABC transporter K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000006011 241.0
HKD1_k127_4696822_23 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000008944 201.0
HKD1_k127_4696822_24 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000002442 200.0
HKD1_k127_4696822_25 methylamine dehydrogenase accessory protein MauD - - - 0.000000000000000000000000000000000000000000000000000003925 205.0
HKD1_k127_4696822_26 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000005923 188.0
HKD1_k127_4696822_27 PFAM Paraquat-inducible protein A K03808 - - 0.0000000000000000000000000000000000000000000000000005292 192.0
HKD1_k127_4696822_28 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000006254 198.0
HKD1_k127_4696822_29 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000001958 192.0
HKD1_k127_4696822_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 544.0
HKD1_k127_4696822_30 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000007824 178.0
HKD1_k127_4696822_31 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000002212 175.0
HKD1_k127_4696822_33 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000001049 159.0
HKD1_k127_4696822_35 Haem-NO-binding - - - 0.0000000000000000000000000000000003949 139.0
HKD1_k127_4696822_36 17 kDa outer membrane surface antigen - - - 0.0000000000000000000000000000003015 136.0
HKD1_k127_4696822_37 Cytochrome c - - - 0.0000000000000000000000127 109.0
HKD1_k127_4696822_38 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000000001927 117.0
HKD1_k127_4696822_39 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000009245 108.0
HKD1_k127_4696822_4 PFAM Mammalian cell entry related domain protein K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 462.0
HKD1_k127_4696822_40 Mo-molybdopterin cofactor metabolic process K03636 - - 0.0000000000000000000002455 109.0
HKD1_k127_4696822_41 Methylamine utilisation protein MauE - - - 0.0000000000000000000006255 102.0
HKD1_k127_4696822_42 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000001546 94.0
HKD1_k127_4696822_43 Belongs to the ompA family - - - 0.00000000000000949 87.0
HKD1_k127_4696822_44 - - - - 0.00000000000005432 78.0
HKD1_k127_4696822_45 Inner membrane component of T3SS, cytoplasmic domain - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.00000000001802 78.0
HKD1_k127_4696822_46 YsiA-like protein, C-terminal region K09017 - - 0.0000000001149 72.0
HKD1_k127_4696822_47 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000001147 71.0
HKD1_k127_4696822_48 Bacterial regulatory proteins, tetR family K16137 - - 0.000004679 56.0
HKD1_k127_4696822_5 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 418.0
HKD1_k127_4696822_50 Calcium ion binding - GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005783,GO:0005788,GO:0006996,GO:0007030,GO:0008150,GO:0009987,GO:0010256,GO:0012505,GO:0016043,GO:0031974,GO:0031981,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0070013,GO:0071840 - 0.00008968 50.0
HKD1_k127_4696822_51 TRL-like protein family - - - 0.0002383 48.0
HKD1_k127_4696822_6 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 398.0
HKD1_k127_4696822_7 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 402.0
HKD1_k127_4696822_8 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 389.0
HKD1_k127_4696822_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 375.0
HKD1_k127_4699571_0 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 0.0 1151.0
HKD1_k127_4699571_1 NADH:flavin oxidoreductase / NADH oxidase family K00317 - 1.5.8.1,1.5.8.2 2.775e-230 734.0
HKD1_k127_4699571_10 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 445.0
HKD1_k127_4699571_11 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 443.0
HKD1_k127_4699571_12 NADH flavin oxidoreductase NADH oxidase K22347 - 1.8.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 429.0
HKD1_k127_4699571_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 408.0
HKD1_k127_4699571_14 Luciferase-like monooxygenase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 390.0
HKD1_k127_4699571_15 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 329.0
HKD1_k127_4699571_16 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 334.0
HKD1_k127_4699571_17 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 328.0
HKD1_k127_4699571_18 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 319.0
HKD1_k127_4699571_19 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 306.0
HKD1_k127_4699571_2 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 5.908e-221 719.0
HKD1_k127_4699571_20 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008208 301.0
HKD1_k127_4699571_21 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002124 282.0
HKD1_k127_4699571_22 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008877 266.0
HKD1_k127_4699571_23 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005631 245.0
HKD1_k127_4699571_24 Ethylbenzene dehydrogenase K17052 - - 0.000000000000000000000000000000000000000000000001269 184.0
HKD1_k127_4699571_25 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000003122 173.0
HKD1_k127_4699571_26 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000003652 179.0
HKD1_k127_4699571_27 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000000002847 155.0
HKD1_k127_4699571_28 MaoC like domain - - - 0.0000000000000000000000000000000000000001107 173.0
HKD1_k127_4699571_29 SnoaL-like domain - - - 0.000000000000000000000000000000000000002665 151.0
HKD1_k127_4699571_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 645.0
HKD1_k127_4699571_30 SnoaL-like domain - - - 0.00000000000000000000000000000000000008057 147.0
HKD1_k127_4699571_31 SnoaL-like domain - - - 0.000000000000000000000000000000006976 148.0
HKD1_k127_4699571_32 Ankyrin repeat domain-containing protein 50-like K21440 - - 0.00000000000000000000000000001101 136.0
HKD1_k127_4699571_33 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000003348 102.0
HKD1_k127_4699571_34 Sel1 repeat K07126 - - 0.00000000000000003164 96.0
HKD1_k127_4699571_36 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000001733 80.0
HKD1_k127_4699571_37 SCO1/SenC K07152 - - 0.00000000004031 74.0
HKD1_k127_4699571_4 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 571.0
HKD1_k127_4699571_5 4Fe-4S dicluster domain K17048,K17051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 561.0
HKD1_k127_4699571_6 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 550.0
HKD1_k127_4699571_7 Thiolase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 505.0
HKD1_k127_4699571_8 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 487.0
HKD1_k127_4699571_9 FAD binding domain K16051 - 1.3.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 464.0
HKD1_k127_473741_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 2.439e-217 706.0
HKD1_k127_473741_1 FAD dependent oxidoreductase K05898 - 1.3.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 617.0
HKD1_k127_473741_2 2-Nitropropane dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 490.0
HKD1_k127_473741_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 431.0
HKD1_k127_473741_4 Protein of unknown function (DUF1214) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 419.0
HKD1_k127_473741_5 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 298.0
HKD1_k127_473741_6 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 302.0
HKD1_k127_473741_7 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004599 294.0
HKD1_k127_473741_8 CoA-transferase family III K07543 - 2.8.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000006151 275.0
HKD1_k127_473741_9 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000006749 197.0
HKD1_k127_474635_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1443.0
HKD1_k127_474635_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.781e-282 887.0
HKD1_k127_474635_10 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 475.0
HKD1_k127_474635_11 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 470.0
HKD1_k127_474635_12 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 460.0
HKD1_k127_474635_13 4-alpha-glucanotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 474.0
HKD1_k127_474635_14 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 444.0
HKD1_k127_474635_15 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 434.0
HKD1_k127_474635_16 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 408.0
HKD1_k127_474635_17 biosynthesis protein E K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 402.0
HKD1_k127_474635_18 acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 368.0
HKD1_k127_474635_19 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 352.0
HKD1_k127_474635_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.917e-272 858.0
HKD1_k127_474635_20 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 349.0
HKD1_k127_474635_21 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 347.0
HKD1_k127_474635_22 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 295.0
HKD1_k127_474635_23 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005161 288.0
HKD1_k127_474635_24 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002858 283.0
HKD1_k127_474635_25 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000295 293.0
HKD1_k127_474635_26 COG0659 Sulfate permease and related transporters (MFS K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003985 283.0
HKD1_k127_474635_27 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000168 258.0
HKD1_k127_474635_28 Nicotinamidase K08281 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000002399 263.0
HKD1_k127_474635_29 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009472 265.0
HKD1_k127_474635_3 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 9.49e-244 776.0
HKD1_k127_474635_30 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009766 244.0
HKD1_k127_474635_31 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.000000000000000000000000000000000000000000000000000000000000000000003004 245.0
HKD1_k127_474635_32 Acetyl-CoA dehydrogenase C-terminal like - - - 0.00000000000000000000000000000000000000000000000000000000000000004166 246.0
HKD1_k127_474635_33 PFAM Multi antimicrobial extrusion protein MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000005475 216.0
HKD1_k127_474635_34 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000005715 213.0
HKD1_k127_474635_35 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000000000000000000000000000000000284 205.0
HKD1_k127_474635_36 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000001338 207.0
HKD1_k127_474635_37 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000003571 194.0
HKD1_k127_474635_38 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000002738 203.0
HKD1_k127_474635_39 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000008576 191.0
HKD1_k127_474635_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.206e-222 710.0
HKD1_k127_474635_40 CHRD domain - - - 0.00000000000000000000000000000000000000000000002181 177.0
HKD1_k127_474635_41 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000327 186.0
HKD1_k127_474635_42 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000006141 173.0
HKD1_k127_474635_43 translation release factor activity - - - 0.0000000000000000000000000000000000000001623 171.0
HKD1_k127_474635_44 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000008321 152.0
HKD1_k127_474635_45 Rdx family K07401 - - 0.000000000000000000000000000000000000005026 147.0
HKD1_k127_474635_46 Ferric uptake regulator family K03711,K09825 - - 0.000000000000000000000000000000000002984 148.0
HKD1_k127_474635_47 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000000008063 154.0
HKD1_k127_474635_48 Fibronectin-binding protein - - - 0.0000000000000000000000000000000003886 149.0
HKD1_k127_474635_49 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000001319 139.0
HKD1_k127_474635_5 DNA polymerase IV (family X) K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 590.0
HKD1_k127_474635_50 IMP dehydrogenase activity - - - 0.00000000000000000000004477 107.0
HKD1_k127_474635_51 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000211 100.0
HKD1_k127_474635_52 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000003798 100.0
HKD1_k127_474635_53 membrane K08988 - - 0.000000000000000004032 87.0
HKD1_k127_474635_54 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000007642 95.0
HKD1_k127_474635_55 Phosphopantetheine attachment site - - - 0.0000000000000004331 91.0
HKD1_k127_474635_56 regulation of translation K03704,K05809 - - 0.0000000000001145 81.0
HKD1_k127_474635_57 - - - - 0.0000000000002211 79.0
HKD1_k127_474635_58 ABC-2 family transporter protein K19341 - - 0.000000001074 70.0
HKD1_k127_474635_59 L,D-transpeptidase catalytic domain - - - 0.000005043 59.0
HKD1_k127_474635_6 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 551.0
HKD1_k127_474635_60 tetratricopeptide repeat - - - 0.0004417 54.0
HKD1_k127_474635_61 - - - - 0.0008132 49.0
HKD1_k127_474635_7 Transketolase, C-terminal domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 529.0
HKD1_k127_474635_8 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 503.0
HKD1_k127_474635_9 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 497.0
HKD1_k127_4750507_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 516.0
HKD1_k127_4750507_1 B domain of TMEM189, localisation domain K20656 - - 0.0000000000000000000000000000000000000000006317 166.0
HKD1_k127_4756363_0 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 502.0
HKD1_k127_4756363_1 phosphatase activity K07025 - - 0.000000000000000000000000004949 125.0
HKD1_k127_4756363_2 - - - - 0.00000000000000000004355 106.0
HKD1_k127_4756363_3 Phosphotransferase K07028 - - 0.0001261 51.0
HKD1_k127_4775333_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 613.0
HKD1_k127_4775333_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 450.0
HKD1_k127_4775333_10 PilZ domain - - - 0.00000004278 63.0
HKD1_k127_4775333_2 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 456.0
HKD1_k127_4775333_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 394.0
HKD1_k127_4775333_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 310.0
HKD1_k127_4775333_5 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006966 285.0
HKD1_k127_4775333_6 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000005935 183.0
HKD1_k127_4775333_7 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000004752 191.0
HKD1_k127_4775333_8 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000009087 129.0
HKD1_k127_4775333_9 - - - - 0.0000000002212 74.0
HKD1_k127_4784839_0 - - - - 0.0 1113.0
HKD1_k127_4784839_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 7.314e-305 944.0
HKD1_k127_4784839_10 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003363 251.0
HKD1_k127_4784839_11 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000000000002768 244.0
HKD1_k127_4784839_12 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000008119 201.0
HKD1_k127_4784839_13 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000006996 197.0
HKD1_k127_4784839_14 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000004288 188.0
HKD1_k127_4784839_15 KR domain K07124 - - 0.000000000000000000000000000000000000000000001621 190.0
HKD1_k127_4784839_16 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000004629 161.0
HKD1_k127_4784839_17 NUDIX domain K00077,K01092,K03574,K03795 - 1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3 0.000000000000000000000000003072 117.0
HKD1_k127_4784839_18 DMT(Drug metabolite transporter) superfamily permease - - - 0.00000000000000000002021 93.0
HKD1_k127_4784839_19 Domain of unknown function (DUF4445) - - - 0.0000000007223 72.0
HKD1_k127_4784839_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.876e-209 671.0
HKD1_k127_4784839_20 COG4235 Cytochrome c biogenesis factor K02200 - - 0.000003435 58.0
HKD1_k127_4784839_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 464.0
HKD1_k127_4784839_4 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 458.0
HKD1_k127_4784839_5 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 392.0
HKD1_k127_4784839_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 395.0
HKD1_k127_4784839_7 Belongs to the TPP enzyme family K04103 - 4.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 342.0
HKD1_k127_4784839_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 303.0
HKD1_k127_4784839_9 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001183 263.0
HKD1_k127_4834336_0 adenosylhomocysteinase activity K01251 - 3.3.1.1 2.91e-199 628.0
HKD1_k127_4834336_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 534.0
HKD1_k127_4834336_10 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005224 290.0
HKD1_k127_4834336_11 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009055 261.0
HKD1_k127_4834336_12 SecD/SecF GG Motif K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000002247 244.0
HKD1_k127_4834336_13 PFAM Stage II sporulation D domain protein K06381 - - 0.00000000000000000000000000000000000000000000000000001062 206.0
HKD1_k127_4834336_14 SnoaL-like domain K06893 - - 0.000000000000000000000000000000000000000000000000297 182.0
HKD1_k127_4834336_15 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 - - 0.000000000000000000000000000000000000000000003876 171.0
HKD1_k127_4834336_16 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000004544 168.0
HKD1_k127_4834336_17 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000006786 126.0
HKD1_k127_4834336_18 Polymer-forming cytoskeletal - - - 0.000000000000000000000000001019 119.0
HKD1_k127_4834336_19 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000001587 93.0
HKD1_k127_4834336_2 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 490.0
HKD1_k127_4834336_20 PFAM CBS domain containing protein - - - 0.0000000000000005868 87.0
HKD1_k127_4834336_21 Outer membrane efflux protein K12340 - - 0.000000000001737 74.0
HKD1_k127_4834336_22 PTS HPr component phosphorylation site K11189 - - 0.00000000005562 72.0
HKD1_k127_4834336_23 Hydrogenase maturation protease K03605 - - 0.000000000218 74.0
HKD1_k127_4834336_24 protein conserved in bacteria K09774 - - 0.000002384 61.0
HKD1_k127_4834336_25 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.0007743 49.0
HKD1_k127_4834336_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 471.0
HKD1_k127_4834336_4 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 438.0
HKD1_k127_4834336_5 4Fe-4S dicluster domain K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 393.0
HKD1_k127_4834336_6 Protein export membrane protein K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 385.0
HKD1_k127_4834336_7 PFAM ABC transporter related K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 301.0
HKD1_k127_4834336_8 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002152 299.0
HKD1_k127_4834336_9 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004064 287.0
HKD1_k127_4859137_0 Protein export membrane protein K03296,K18138 - - 0.0 1266.0
HKD1_k127_4859137_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1261.0
HKD1_k127_4859137_10 Outer membrane efflux protein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 422.0
HKD1_k127_4859137_11 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 353.0
HKD1_k127_4859137_12 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004562 294.0
HKD1_k127_4859137_13 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000002644 186.0
HKD1_k127_4859137_14 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000001805 164.0
HKD1_k127_4859137_15 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000657 162.0
HKD1_k127_4859137_16 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000004203 164.0
HKD1_k127_4859137_17 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001265 160.0
HKD1_k127_4859137_18 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000004132 141.0
HKD1_k127_4859137_19 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000002211 137.0
HKD1_k127_4859137_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.992e-316 993.0
HKD1_k127_4859137_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000001328 119.0
HKD1_k127_4859137_21 Domain of unknown function (DUF1844) - - - 0.0000000000000002775 91.0
HKD1_k127_4859137_22 PFAM Colicin V production protein K03558 - - 0.000000001952 66.0
HKD1_k127_4859137_3 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 4.382e-260 819.0
HKD1_k127_4859137_4 Flavin containing amine oxidoreductase - - - 2.188e-197 637.0
HKD1_k127_4859137_5 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 586.0
HKD1_k127_4859137_6 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 578.0
HKD1_k127_4859137_7 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 398.0
HKD1_k127_4859137_8 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 419.0
HKD1_k127_4859137_9 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 392.0
HKD1_k127_5016663_0 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 1.114e-194 646.0
HKD1_k127_5016663_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 580.0
HKD1_k127_5016663_10 PFAM RNA recognition motif - - - 0.0000000000000000000000000000005043 128.0
HKD1_k127_5016663_11 Hemerythrin hhe cation binding - - - 0.00000000000000000000000000216 117.0
HKD1_k127_5016663_12 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000000001258 125.0
HKD1_k127_5016663_13 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000008502 121.0
HKD1_k127_5016663_14 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000003423 92.0
HKD1_k127_5016663_15 Plasmid stabilization - - - 0.0000000000000000008764 95.0
HKD1_k127_5016663_16 COG1145 Ferredoxin - - - 0.000000000000000002503 96.0
HKD1_k127_5016663_17 AI-2E family transporter - - - 0.000000000000000218 89.0
HKD1_k127_5016663_18 Protein of unknown function (DUF3309) - - - 0.0000000000001236 80.0
HKD1_k127_5016663_19 Hexapeptide repeat of succinyl-transferase K00661 - 2.3.1.79 0.0000000000001466 81.0
HKD1_k127_5016663_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 488.0
HKD1_k127_5016663_20 UPF0391 membrane protein - - - 0.000000000001261 72.0
HKD1_k127_5016663_21 - - - - 0.00000000007111 70.0
HKD1_k127_5016663_22 - - - - 0.000000108 61.0
HKD1_k127_5016663_23 protein kinase activity - - - 0.000004409 58.0
HKD1_k127_5016663_24 Phospholipase D Active site motif K01115 - 3.1.4.4 0.000945 43.0
HKD1_k127_5016663_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 379.0
HKD1_k127_5016663_4 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003114 269.0
HKD1_k127_5016663_5 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000007421 221.0
HKD1_k127_5016663_6 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000000000007921 220.0
HKD1_k127_5016663_7 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000001558 204.0
HKD1_k127_5016663_8 Universal stress protein family - - - 0.0000000000000000000000000000000006524 149.0
HKD1_k127_5016663_9 phosphorelay signal transduction system - - - 0.00000000000000000000000000000001013 136.0
HKD1_k127_5021708_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 615.0
HKD1_k127_5021708_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 511.0
HKD1_k127_5021708_10 pfam abc1 - - - 0.000000000000000000000000000000000000000000000000000000000000000001626 243.0
HKD1_k127_5021708_11 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000003473 254.0
HKD1_k127_5021708_12 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000005734 196.0
HKD1_k127_5021708_13 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000002312 179.0
HKD1_k127_5021708_14 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000001565 175.0
HKD1_k127_5021708_15 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000002246 147.0
HKD1_k127_5021708_16 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000008448 159.0
HKD1_k127_5021708_17 Cytochrome C assembly protein - - - 0.000000000000000000000000000001541 131.0
HKD1_k127_5021708_18 Appr-1'-p processing enzyme - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000003049 137.0
HKD1_k127_5021708_19 - - - - 0.0000000000000002483 91.0
HKD1_k127_5021708_2 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 498.0
HKD1_k127_5021708_20 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00003453 46.0
HKD1_k127_5021708_3 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 424.0
HKD1_k127_5021708_4 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 417.0
HKD1_k127_5021708_5 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 354.0
HKD1_k127_5021708_6 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 329.0
HKD1_k127_5021708_7 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 316.0
HKD1_k127_5021708_8 pfam abc K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 302.0
HKD1_k127_5021708_9 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 321.0
HKD1_k127_5049657_0 General secretory system II, protein E domain protein K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 579.0
HKD1_k127_5049657_1 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 540.0
HKD1_k127_5049657_10 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001028 289.0
HKD1_k127_5049657_11 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001244 265.0
HKD1_k127_5049657_12 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000009893 218.0
HKD1_k127_5049657_13 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000001473 222.0
HKD1_k127_5049657_14 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000007031 222.0
HKD1_k127_5049657_15 PFAM luciferase family protein - - - 0.0000000000000000000000000000000000000000000000000000000008719 216.0
HKD1_k127_5049657_16 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000001699 210.0
HKD1_k127_5049657_17 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000002131 205.0
HKD1_k127_5049657_18 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000000000004935 167.0
HKD1_k127_5049657_19 arginine transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000005968 170.0
HKD1_k127_5049657_2 PFAM acyl-CoA dehydrogenase domain protein K00249,K11731 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 472.0
HKD1_k127_5049657_20 Thiol-disulfide oxidoreductase DCC - - - 0.000000000000000000000000000000000000000001266 164.0
HKD1_k127_5049657_21 PFAM PfkB domain protein K00847,K00852 - 2.7.1.15,2.7.1.4 0.000000000000000000000000000000000000005781 157.0
HKD1_k127_5049657_22 transcriptional regulator - - - 0.000000000000000000000000000000000001848 146.0
HKD1_k127_5049657_23 Peptidase C26 K07010 - - 0.000000000000000000000000000000000004762 156.0
HKD1_k127_5049657_24 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain - - - 0.000000000000000000000000000000005123 136.0
HKD1_k127_5049657_25 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000000002845 132.0
HKD1_k127_5049657_26 transcriptional regulator - - - 0.000000000000000000000000001431 125.0
HKD1_k127_5049657_27 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.00000000000000000000000002939 124.0
HKD1_k127_5049657_28 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000001252 106.0
HKD1_k127_5049657_29 EamA-like transporter family - - - 0.000000000000003951 87.0
HKD1_k127_5049657_3 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 468.0
HKD1_k127_5049657_30 Z1 domain - - - 0.0000000000000347 75.0
HKD1_k127_5049657_31 Type II secretory pathway, component - - - 0.00000001756 68.0
HKD1_k127_5049657_32 Cupin domain - - - 0.00001179 55.0
HKD1_k127_5049657_33 Domain of unknown function (DUF4404) - - - 0.000178 53.0
HKD1_k127_5049657_4 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 414.0
HKD1_k127_5049657_5 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 404.0
HKD1_k127_5049657_6 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 395.0
HKD1_k127_5049657_7 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 377.0
HKD1_k127_5049657_8 Steryl acetyl hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 311.0
HKD1_k127_5049657_9 Belongs to the MenA family. Type 1 subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 314.0
HKD1_k127_5084569_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 3.506e-195 628.0
HKD1_k127_5084569_1 Acyl-CoA synthetase (NDP forming) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 578.0
HKD1_k127_5084569_10 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000007179 192.0
HKD1_k127_5084569_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000002241 177.0
HKD1_k127_5084569_12 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000001003 149.0
HKD1_k127_5084569_13 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000001836 142.0
HKD1_k127_5084569_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000003606 156.0
HKD1_k127_5084569_15 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000001074 118.0
HKD1_k127_5084569_16 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000002333 113.0
HKD1_k127_5084569_17 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000001646 109.0
HKD1_k127_5084569_18 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000008356 101.0
HKD1_k127_5084569_19 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000001878 96.0
HKD1_k127_5084569_2 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 493.0
HKD1_k127_5084569_20 response regulator K02483,K07666 - - 0.000000000000001672 91.0
HKD1_k127_5084569_21 Lipase maturation factor - - - 0.00000000007369 67.0
HKD1_k127_5084569_22 lipolytic protein G-D-S-L family K20306 - - 0.000000009299 69.0
HKD1_k127_5084569_23 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000001178 62.0
HKD1_k127_5084569_24 Tetratricopeptide TPR_2 repeat protein - - - 0.000007797 60.0
HKD1_k127_5084569_3 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 455.0
HKD1_k127_5084569_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 419.0
HKD1_k127_5084569_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 397.0
HKD1_k127_5084569_6 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 351.0
HKD1_k127_5084569_7 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 310.0
HKD1_k127_5084569_8 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004377 231.0
HKD1_k127_5084569_9 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000004842 218.0
HKD1_k127_5085026_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 382.0
HKD1_k127_5085026_1 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001292 282.0
HKD1_k127_5085026_2 SOS response associated peptidase (SRAP) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000184 257.0
HKD1_k127_5085026_3 Cation efflux family K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000001847 248.0
HKD1_k127_5085026_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000001856 223.0
HKD1_k127_5101557_0 Phosphoenolpyruvate carboxylase K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 3.916e-199 655.0
HKD1_k127_5101557_1 Belongs to the alpha-IPM synthase homocitrate synthase family K09011 - 2.3.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 531.0
HKD1_k127_5101557_2 o-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002271 278.0
HKD1_k127_5101557_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000008305 233.0
HKD1_k127_5101557_4 pseudouridine synthase activity K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000001437 191.0
HKD1_k127_5101557_5 PFAM Metallophosphoesterase K07098 - - 0.0000000000000000000003284 109.0
HKD1_k127_5101557_6 peptidyl-tyrosine sulfation - - - 0.000000000000224 78.0
HKD1_k127_5101557_7 COG0457 FOG TPR repeat - - - 0.0000000000004073 79.0
HKD1_k127_5101557_8 Acetyltransferase (GNAT) domain - - - 0.0000000000267 75.0
HKD1_k127_5101557_9 flavodoxin nitric oxide synthase K03809 - 1.6.5.2 0.000000000181 74.0
HKD1_k127_510325_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1194.0
HKD1_k127_510325_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 8.274e-313 1010.0
HKD1_k127_510325_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000002573 244.0
HKD1_k127_510325_11 Major facilitator Superfamily K03292 - - 0.000000000000000000000000000000000000000000000000000000000003579 227.0
HKD1_k127_510325_12 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000007346 213.0
HKD1_k127_510325_13 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000006408 221.0
HKD1_k127_510325_14 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000004667 209.0
HKD1_k127_510325_15 Zn peptidase - - - 0.000000000000000000000000000000000000000000000005073 198.0
HKD1_k127_510325_16 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000001442 171.0
HKD1_k127_510325_17 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000002724 171.0
HKD1_k127_510325_18 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000001889 177.0
HKD1_k127_510325_19 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000003624 143.0
HKD1_k127_510325_2 Sulfatase K01130 - 3.1.6.1 4.89e-262 821.0
HKD1_k127_510325_20 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000008861 152.0
HKD1_k127_510325_21 Transcription elongation factor, GreA/GreB, C-term - - - 0.0000000000000000000000000000000001079 144.0
HKD1_k127_510325_22 Protein of unknown function (DUF3530) - - - 0.000000000000000000000001314 109.0
HKD1_k127_510325_23 hemerythrin HHE cation binding domain - - - 0.000000000000000000006001 100.0
HKD1_k127_510325_25 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000001224 81.0
HKD1_k127_510325_27 transferase activity, transferring glycosyl groups - - - 0.000000001063 70.0
HKD1_k127_510325_28 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000086 61.0
HKD1_k127_510325_29 CAAX protease self-immunity K07052 - - 0.000005908 61.0
HKD1_k127_510325_3 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 552.0
HKD1_k127_510325_4 COG0076 Glutamate decarboxylase and related PLP-dependent K01634 - 4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 518.0
HKD1_k127_510325_5 Converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 504.0
HKD1_k127_510325_6 3-isopropylmalate dehydrogenase activity K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 452.0
HKD1_k127_510325_7 glutamyl-tRNA(Gln) amidotransferase subunit A K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 442.0
HKD1_k127_510325_8 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 374.0
HKD1_k127_510325_9 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 381.0
HKD1_k127_5130765_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.281e-233 745.0
HKD1_k127_5130765_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 501.0
HKD1_k127_5130765_2 ABC 3 transport family K09816,K09819 - - 0.0000000000000000000000000000000000000000000001013 179.0
HKD1_k127_5130765_3 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000001085 144.0
HKD1_k127_5130765_4 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K07004 - 3.4.24.40 0.00000000000000000000000000065 130.0
HKD1_k127_5130765_5 metallopeptidase activity K01637 - 4.1.3.1 0.0000000000002858 83.0
HKD1_k127_5149446_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4e-323 1004.0
HKD1_k127_5149446_1 Flavin-binding monooxygenase-like K10215 - - 5.631e-215 677.0
HKD1_k127_5149446_10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 303.0
HKD1_k127_5149446_11 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 287.0
HKD1_k127_5149446_12 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002457 279.0
HKD1_k127_5149446_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002591 270.0
HKD1_k127_5149446_14 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001193 268.0
HKD1_k127_5149446_15 phosphoribosyltransferase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000004303 244.0
HKD1_k127_5149446_16 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000004191 254.0
HKD1_k127_5149446_17 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000000003065 234.0
HKD1_k127_5149446_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001805 231.0
HKD1_k127_5149446_19 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000173 196.0
HKD1_k127_5149446_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.751e-195 630.0
HKD1_k127_5149446_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000002975 181.0
HKD1_k127_5149446_22 COG3000 Sterol desaturase - - - 0.000000000000000000000000000000000000000000458 168.0
HKD1_k127_5149446_23 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000009175 173.0
HKD1_k127_5149446_24 Helix-turn-helix - - - 0.00000000000000000000000000000006776 130.0
HKD1_k127_5149446_25 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000002731 111.0
HKD1_k127_5149446_26 - - - - 0.0000000000000000000000004274 112.0
HKD1_k127_5149446_27 IMP dehydrogenase activity - GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0035821,GO:0036293,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070482,GO:0071944,GO:0075136 - 0.0000000000000000000003406 109.0
HKD1_k127_5149446_28 Trypsin-like peptidase domain - - - 0.0000000000000000000006655 106.0
HKD1_k127_5149446_29 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000564 89.0
HKD1_k127_5149446_3 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 466.0
HKD1_k127_5149446_30 - - - - 0.000000000000002004 83.0
HKD1_k127_5149446_31 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000007432 77.0
HKD1_k127_5149446_32 PFAM CBS domain containing protein K04767 - - 0.00000000000001303 89.0
HKD1_k127_5149446_33 Sterol carrier protein - - - 0.00000000001642 78.0
HKD1_k127_5149446_34 Prokaryotic dksA traR C4-type zinc finger - - - 0.000001819 62.0
HKD1_k127_5149446_35 - - - - 0.00006518 54.0
HKD1_k127_5149446_36 DnaK suppressor protein - - - 0.0006819 50.0
HKD1_k127_5149446_4 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 451.0
HKD1_k127_5149446_5 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 418.0
HKD1_k127_5149446_6 KR domain - GO:0000166,GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006694,GO:0006703,GO:0008150,GO:0008152,GO:0008202,GO:0008210,GO:0008289,GO:0008610,GO:0009058,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0010817,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0033764,GO:0034754,GO:0036094,GO:0040007,GO:0042445,GO:0042446,GO:0042562,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051704,GO:0055114,GO:0065007,GO:0065008,GO:0070401,GO:0071704,GO:0097159,GO:0099130,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903924 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 377.0
HKD1_k127_5149446_7 Belongs to the long-chain O-acyltransferase family K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 359.0
HKD1_k127_5149446_8 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 352.0
HKD1_k127_5149446_9 Metal-dependent hydrolase K07044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 344.0
HKD1_k127_5205063_0 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 513.0
HKD1_k127_5205063_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008124 497.0
HKD1_k127_5205063_2 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 462.0
HKD1_k127_5205063_3 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 428.0
HKD1_k127_5205063_4 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001634 278.0
HKD1_k127_5205063_5 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) - - - 0.00000000000000000000000000000000000000000000000000000001152 222.0
HKD1_k127_5205063_6 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000000001372 163.0
HKD1_k127_5205063_7 chorismate binding enzyme K02552 - 5.4.4.2 0.000000000000004399 76.0
HKD1_k127_5211632_0 Extracellular solute-binding protein, family 5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 505.0
HKD1_k127_5211632_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 377.0
HKD1_k127_5211632_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 348.0
HKD1_k127_5211632_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002221 290.0
HKD1_k127_5211632_4 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000001832 129.0
HKD1_k127_5211632_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000002937 57.0
HKD1_k127_5211632_6 serine threonine protein kinase - - - 0.0000743 53.0
HKD1_k127_5225217_0 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003854 266.0
HKD1_k127_5225217_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000002328 198.0
HKD1_k127_5225217_2 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000003096 157.0
HKD1_k127_5225217_3 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000001974 80.0
HKD1_k127_5225217_4 Two component signalling adaptor domain K03408 - - 0.000004618 59.0
HKD1_k127_5286274_0 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000103 211.0
HKD1_k127_5286274_1 Histidine kinase - - - 0.00000000000000000000000000000000000000538 165.0
HKD1_k127_5286274_2 cAMP biosynthetic process - - - 0.0000000005496 68.0
HKD1_k127_5306496_0 General secretory system II, protein E domain protein K02652 - - 5.979e-263 820.0
HKD1_k127_5306496_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 611.0
HKD1_k127_5306496_10 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 324.0
HKD1_k127_5306496_11 Anhydro-N-acetylmuramic acid kinase K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 316.0
HKD1_k127_5306496_12 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 329.0
HKD1_k127_5306496_13 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 327.0
HKD1_k127_5306496_14 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 302.0
HKD1_k127_5306496_15 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001141 294.0
HKD1_k127_5306496_16 ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002014 297.0
HKD1_k127_5306496_17 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002784 287.0
HKD1_k127_5306496_18 Belongs to the sigma-70 factor family K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005629 260.0
HKD1_k127_5306496_19 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001132 284.0
HKD1_k127_5306496_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 505.0
HKD1_k127_5306496_20 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000507 254.0
HKD1_k127_5306496_21 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000003952 241.0
HKD1_k127_5306496_22 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000001415 256.0
HKD1_k127_5306496_23 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000106 231.0
HKD1_k127_5306496_24 Protein phosphatase 2C K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000002753 198.0
HKD1_k127_5306496_25 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000001008 193.0
HKD1_k127_5306496_26 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000004905 188.0
HKD1_k127_5306496_27 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000002005 192.0
HKD1_k127_5306496_28 Histidine kinase - - - 0.000000000000000000000000000000000000000000001348 185.0
HKD1_k127_5306496_29 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000001821 171.0
HKD1_k127_5306496_3 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 501.0
HKD1_k127_5306496_30 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000342 173.0
HKD1_k127_5306496_31 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000001151 166.0
HKD1_k127_5306496_32 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000003152 143.0
HKD1_k127_5306496_33 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000003631 143.0
HKD1_k127_5306496_34 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000001396 139.0
HKD1_k127_5306496_35 response regulator - - - 0.000000000000000000001046 111.0
HKD1_k127_5306496_36 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000595 102.0
HKD1_k127_5306496_37 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000006125 83.0
HKD1_k127_5306496_38 RHS Repeat - - - 0.00000000000001701 85.0
HKD1_k127_5306496_39 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000009215 83.0
HKD1_k127_5306496_4 response regulator K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 467.0
HKD1_k127_5306496_40 - - - - 0.0000000000007713 81.0
HKD1_k127_5306496_41 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000485 76.0
HKD1_k127_5306496_42 Type IV Pilus-assembly protein W K02672 - - 0.0000000747 64.0
HKD1_k127_5306496_43 Prokaryotic N-terminal methylation motif K08084 - - 0.0000004526 59.0
HKD1_k127_5306496_44 Peptidase S24-like - - - 0.0001686 48.0
HKD1_k127_5306496_5 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 409.0
HKD1_k127_5306496_6 Nucleoside recognition K06374 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 398.0
HKD1_k127_5306496_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 377.0
HKD1_k127_5306496_8 pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 370.0
HKD1_k127_5306496_9 response regulator K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 377.0
HKD1_k127_536220_0 Heat shock 70 kDa protein K04043 - - 1.809e-266 833.0
HKD1_k127_536220_1 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 449.0
HKD1_k127_536220_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000506 149.0
HKD1_k127_536220_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000004918 108.0
HKD1_k127_5456942_0 belongs to the aldehyde dehydrogenase family K00130,K00151 - 1.2.1.60,1.2.1.8 1.16e-222 701.0
HKD1_k127_5456942_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 596.0
HKD1_k127_5456942_10 3,4-dihydroxyphenylacetate 2,3-dioxygenase' K00455 - 1.13.11.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000001058 268.0
HKD1_k127_5456942_11 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001823 274.0
HKD1_k127_5456942_12 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000002456 227.0
HKD1_k127_5456942_13 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000006189 211.0
HKD1_k127_5456942_14 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000157 202.0
HKD1_k127_5456942_15 transcriptional regulator - - - 0.0000000000000000000000000000000000000002657 151.0
HKD1_k127_5456942_16 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000002443 156.0
HKD1_k127_5456942_17 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000006655 117.0
HKD1_k127_5456942_18 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K07264 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016763,GO:0033692,GO:0034637,GO:0034645,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.2.43 0.000000000000000000001586 110.0
HKD1_k127_5456942_19 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.00001098 48.0
HKD1_k127_5456942_2 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 573.0
HKD1_k127_5456942_3 Fumarylacetoacetate (FAA) hydrolase family K05921 - 4.1.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 422.0
HKD1_k127_5456942_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 430.0
HKD1_k127_5456942_5 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 400.0
HKD1_k127_5456942_6 PFAM aldo keto reductase K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 383.0
HKD1_k127_5456942_7 glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 348.0
HKD1_k127_5456942_8 Formyl transferase K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 305.0
HKD1_k127_5456942_9 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 303.0
HKD1_k127_5475038_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 3.867e-238 751.0
HKD1_k127_5475038_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 9.604e-224 726.0
HKD1_k127_5475038_10 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000000000000005044 200.0
HKD1_k127_5475038_11 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000006983 186.0
HKD1_k127_5475038_12 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K07004 - 3.4.24.40 0.0000000000000000000000000000000000000000000000000169 197.0
HKD1_k127_5475038_13 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000004936 158.0
HKD1_k127_5475038_14 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000071 154.0
HKD1_k127_5475038_15 Trypsin - - - 0.000000000000000000000000004048 128.0
HKD1_k127_5475038_16 RDD family - - - 0.0000000000000000000000001232 123.0
HKD1_k127_5475038_17 carbon dioxide binding K04653,K04654 - - 0.0000000000000000000000003579 123.0
HKD1_k127_5475038_18 denitrification pathway K02569 - - 0.00000000000000000000002426 109.0
HKD1_k127_5475038_19 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000007994 77.0
HKD1_k127_5475038_2 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009978 484.0
HKD1_k127_5475038_20 - - - - 0.000008236 59.0
HKD1_k127_5475038_21 Cytochrome c K00406,K08906 - - 0.00003261 50.0
HKD1_k127_5475038_3 PFAM NADH ubiquinone oxidoreductase, 20 Kd subunit K05927,K06282 - 1.12.5.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 430.0
HKD1_k127_5475038_4 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 443.0
HKD1_k127_5475038_5 COG0625 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 390.0
HKD1_k127_5475038_6 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 353.0
HKD1_k127_5475038_7 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 306.0
HKD1_k127_5475038_8 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 309.0
HKD1_k127_5475038_9 Enoyl-CoA hydratase/isomerase K01692,K13766 - 4.2.1.17,4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000001618 235.0
HKD1_k127_5515507_0 PFAM Amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 329.0
HKD1_k127_5515507_1 - - - - 0.00000000000001479 87.0
HKD1_k127_564139_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 527.0
HKD1_k127_564139_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 495.0
HKD1_k127_564139_10 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 328.0
HKD1_k127_564139_11 Acyl-CoA dehydrogenase, N-terminal domain K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 296.0
HKD1_k127_564139_12 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004579 295.0
HKD1_k127_564139_13 TIGRFAM arsenite-activated ATPase ArsA K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006868 287.0
HKD1_k127_564139_14 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000009793 257.0
HKD1_k127_564139_15 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000004854 245.0
HKD1_k127_564139_16 protein domain, possibly involved in tellurite resistance - - - 0.00000000000000000000000000000000000000000000000000117 189.0
HKD1_k127_564139_17 Methyltransferase, YaeB family - - - 0.00000000000000000000000000000000000000000000001093 176.0
HKD1_k127_564139_18 protein conserved in bacteria K09793 - - 0.00000000000000000000000000000000000000000000003329 180.0
HKD1_k127_564139_19 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000001248 160.0
HKD1_k127_564139_2 PFAM 2-nitropropane dioxygenase NPD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 467.0
HKD1_k127_564139_20 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000003241 174.0
HKD1_k127_564139_21 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000004993 168.0
HKD1_k127_564139_22 Thioesterase superfamily - - - 0.000000000000000000000000000000000000005143 164.0
HKD1_k127_564139_23 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000002151 167.0
HKD1_k127_564139_24 Fumble K09680 - 2.7.1.33 0.0000000000000000000000000000000000001039 154.0
HKD1_k127_564139_25 methyltransferase activity K00563 - 2.1.1.187 0.00000000000000000000000000000000004817 144.0
HKD1_k127_564139_26 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000007543 151.0
HKD1_k127_564139_27 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000001073 146.0
HKD1_k127_564139_28 - - - - 0.000000000008288 73.0
HKD1_k127_564139_29 Drug metabolite transporter - - - 0.000007552 58.0
HKD1_k127_564139_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 447.0
HKD1_k127_564139_4 Cytochrome P450 K05525,K20497 - 1.14.13.151,1.14.15.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 466.0
HKD1_k127_564139_5 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 GO:0003674,GO:0005215,GO:0005372,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006833,GO:0006884,GO:0006950,GO:0006970,GO:0008150,GO:0008361,GO:0009628,GO:0009987,GO:0009992,GO:0015250,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042044,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0050896,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 355.0
HKD1_k127_564139_6 Enoyl-CoA hydratase K01692,K18383 - 4.1.2.41,4.2.1.101,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 357.0
HKD1_k127_564139_7 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 352.0
HKD1_k127_564139_8 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 338.0
HKD1_k127_564139_9 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 315.0
HKD1_k127_5677087_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.861e-247 776.0
HKD1_k127_5677087_1 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 385.0
HKD1_k127_5677087_2 PFAM helix-turn-helix domain protein - - - 0.00000000000000000000000000000000000000000000000000000001259 207.0
HKD1_k127_5677087_3 DoxX - - - 0.00000000000000000000000000000000000000000000004257 174.0
HKD1_k127_5677087_4 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000006686 127.0
HKD1_k127_5677087_5 protein secretion K03116 GO:0008150,GO:0040007 - 0.00000000000000874 79.0
HKD1_k127_5677087_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000001334 58.0
HKD1_k127_568627_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 581.0
HKD1_k127_568627_1 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 476.0
HKD1_k127_568627_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 439.0
HKD1_k127_568627_3 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 357.0
HKD1_k127_568627_4 Sulfate ABC transporter inner membrane subunit CysT K02046 - - 0.0000000000000000000000000000000000000000000000006057 184.0
HKD1_k127_568627_5 Lipoprotein K04754 - - 0.000000000000000000000000000005176 138.0
HKD1_k127_568627_6 Major Facilitator Superfamily - - - 0.00000000000000000000000563 117.0
HKD1_k127_5692807_0 protein methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 536.0
HKD1_k127_5692807_1 asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 511.0
HKD1_k127_5692807_2 COG0367 Asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 353.0
HKD1_k127_5692807_3 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000002217 229.0
HKD1_k127_5692807_4 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000003347 205.0
HKD1_k127_5692807_5 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000001606 131.0
HKD1_k127_5692807_6 - - - - 0.000000000000000000000000001672 126.0
HKD1_k127_5692807_7 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000005121 64.0
HKD1_k127_570541_0 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000005236 208.0
HKD1_k127_570541_1 methyltransferase - - - 0.00000000000000000000000000000000000000004929 164.0
HKD1_k127_570541_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.0000000000000000002544 88.0
HKD1_k127_570541_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000433 63.0
HKD1_k127_5774598_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 7.114e-253 803.0
HKD1_k127_5774598_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 6.754e-239 748.0
HKD1_k127_5774598_10 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000007691 149.0
HKD1_k127_5774598_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000002473 147.0
HKD1_k127_5774598_12 Pfam Pyridoxamine 5'-phosphate - - - 0.000000000000000000000003245 108.0
HKD1_k127_5774598_13 Lytic murein transglycosylase K08309 - - 0.00000000000000000042 96.0
HKD1_k127_5774598_15 - - - - 0.000000000007512 79.0
HKD1_k127_5774598_16 Large extracellular alpha-helical protein - - - 0.000000000424 72.0
HKD1_k127_5774598_17 MORN repeat variant - - - 0.0000008099 59.0
HKD1_k127_5774598_18 Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA K00564,K11391 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052916,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.172,2.1.1.174 0.00008264 50.0
HKD1_k127_5774598_2 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 571.0
HKD1_k127_5774598_3 oxidoreductases (related to aryl-alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 446.0
HKD1_k127_5774598_4 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 411.0
HKD1_k127_5774598_5 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 383.0
HKD1_k127_5774598_6 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 309.0
HKD1_k127_5774598_7 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 312.0
HKD1_k127_5774598_8 Glycine oxidase K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000001373 246.0
HKD1_k127_5774598_9 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000001444 225.0
HKD1_k127_5778769_0 endonuclease activity K07451 - - 0.0000000000000001083 93.0
HKD1_k127_5778769_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000004776 77.0
HKD1_k127_5818594_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 3.502e-285 897.0
HKD1_k127_5818594_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 6.756e-269 836.0
HKD1_k127_5818594_10 - - - - 0.0000000000000000000000000000000000000000000000000000001258 212.0
HKD1_k127_5818594_11 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000004116 192.0
HKD1_k127_5818594_12 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000005549 192.0
HKD1_k127_5818594_13 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000003306 187.0
HKD1_k127_5818594_14 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000004673 157.0
HKD1_k127_5818594_15 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000002638 149.0
HKD1_k127_5818594_16 von willebrand factor, type a K07114 - - 0.000000000000000000000000000002894 140.0
HKD1_k127_5818594_17 von Willebrand factor, type A K07114 - - 0.000000000000000000000000001435 132.0
HKD1_k127_5818594_18 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000008843 103.0
HKD1_k127_5818594_19 Oxygen tolerance - - - 0.00000000000007487 84.0
HKD1_k127_5818594_2 Cytochrome C and Quinol oxidase polypeptide I - - - 7.798e-266 839.0
HKD1_k127_5818594_20 PFAM helix-turn-helix domain protein - - - 0.0000000001204 69.0
HKD1_k127_5818594_21 AsmA-like C-terminal region - - - 0.0000000007713 73.0
HKD1_k127_5818594_3 TIGRFAM phosphoenolpyruvate-protein phosphotransferase K08484 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 539.0
HKD1_k127_5818594_4 PFAM ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 343.0
HKD1_k127_5818594_5 FAD binding domain K21272 - 1.14.13.222 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 357.0
HKD1_k127_5818594_6 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001585 305.0
HKD1_k127_5818594_7 Cytochrome C oxidase subunit II, periplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006582 267.0
HKD1_k127_5818594_8 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000006424 252.0
HKD1_k127_5818594_9 Cytochrome c oxidase subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000002503 226.0
HKD1_k127_5854135_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0 1290.0
HKD1_k127_5854135_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 7.376e-319 988.0
HKD1_k127_5854135_10 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 378.0
HKD1_k127_5854135_11 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 343.0
HKD1_k127_5854135_12 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 334.0
HKD1_k127_5854135_13 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001051 269.0
HKD1_k127_5854135_14 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000001124 240.0
HKD1_k127_5854135_15 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000002223 219.0
HKD1_k127_5854135_16 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000007559 197.0
HKD1_k127_5854135_17 AAA domain - - - 0.00000000000000000000000000000000004895 155.0
HKD1_k127_5854135_18 Putative DNA-binding domain - - - 0.0000000000000000000000000000001186 136.0
HKD1_k127_5854135_19 DoxX-like family K15977 - - 0.00000000000000000000000000006307 130.0
HKD1_k127_5854135_2 Amylo-alpha-1,6-glucosidase - - - 2.726e-263 856.0
HKD1_k127_5854135_20 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000002014 119.0
HKD1_k127_5854135_21 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000004976 94.0
HKD1_k127_5854135_3 choline dehydrogenase activity - - - 6.463e-208 672.0
HKD1_k127_5854135_4 all-trans-retinol 13,14-reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 583.0
HKD1_k127_5854135_5 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 586.0
HKD1_k127_5854135_6 Transmembrane protein of unknown function (DUF3556) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 526.0
HKD1_k127_5854135_7 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 482.0
HKD1_k127_5854135_8 Glucose dehydrogenase C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 407.0
HKD1_k127_5854135_9 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 386.0
HKD1_k127_5868435_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 2.599e-200 644.0
HKD1_k127_5868435_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 444.0
HKD1_k127_5868435_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000166 221.0
HKD1_k127_5868435_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000002489 162.0
HKD1_k127_5868435_4 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000267 158.0
HKD1_k127_5868435_5 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000002336 113.0
HKD1_k127_5868435_6 Pfam:DUF385 - - - 0.00000000000000000000006992 103.0
HKD1_k127_5868435_7 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000008112 94.0
HKD1_k127_5868435_8 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000001385 66.0
HKD1_k127_5875625_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 394.0
HKD1_k127_5875625_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001645 308.0
HKD1_k127_5875625_2 zinc-ribbon domain - - - 0.000000000000000000000000000001781 129.0
HKD1_k127_5875625_3 PFAM CheW domain protein K03408 - - 0.0000000000000000000000005451 111.0
HKD1_k127_5875625_4 Chemotaxis signal transduction protein K03408 - - 0.00000000000000000001717 98.0
HKD1_k127_5988920_0 Asparagine synthase K01953 - 6.3.5.4 1.251e-213 680.0
HKD1_k127_5988920_1 Glycosyltransferase like family 2 K16870 - 2.4.1.289 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 494.0
HKD1_k127_5988920_10 Belongs to the glycosyl hydrolase 43 family K01181,K09955 - 3.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000778 295.0
HKD1_k127_5988920_11 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003228 281.0
HKD1_k127_5988920_12 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000002282 267.0
HKD1_k127_5988920_13 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004029 246.0
HKD1_k127_5988920_14 AAA domain K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000001577 240.0
HKD1_k127_5988920_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001126 246.0
HKD1_k127_5988920_16 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000001358 237.0
HKD1_k127_5988920_17 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.0000000000000000000000000000000000000000000000000000000001826 220.0
HKD1_k127_5988920_18 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000007646 142.0
HKD1_k127_5988920_19 Lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000001048 154.0
HKD1_k127_5988920_2 Protein of unknown function (DUF1349) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 494.0
HKD1_k127_5988920_20 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000004186 117.0
HKD1_k127_5988920_21 Chain length determinant protein - - - 0.000000000000000000000001326 116.0
HKD1_k127_5988920_22 Forkhead associated domain - - - 0.0000000000000007111 81.0
HKD1_k127_5988920_24 Protein of unknown function (FYDLN_acid) - - - 0.00000000000002182 79.0
HKD1_k127_5988920_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 394.0
HKD1_k127_5988920_4 Utp--glucose-1-phosphate uridylyltransferase K00972,K11442 - 2.7.7.23,2.7.7.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 369.0
HKD1_k127_5988920_5 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 370.0
HKD1_k127_5988920_6 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 338.0
HKD1_k127_5988920_7 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 332.0
HKD1_k127_5988920_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 307.0
HKD1_k127_5988920_9 Polysaccharide biosynthesis protein K03328 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002311 287.0
HKD1_k127_6002188_0 Response regulator, receiver K11384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 557.0
HKD1_k127_6002188_1 Histidine kinase K11383 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 484.0
HKD1_k127_6002188_2 Sugar (and other) transporter K08178 - - 0.000000000000000000000000000000002131 144.0
HKD1_k127_6095240_0 Transcriptional regulator K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 387.0
HKD1_k127_6095240_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 359.0
HKD1_k127_6095240_2 Membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000002793 190.0
HKD1_k127_6095240_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000001942 83.0
HKD1_k127_6095240_4 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000005549 89.0
HKD1_k127_6095240_5 Carboxypeptidase regulatory-like domain - - - 0.0005852 48.0
HKD1_k127_6117400_0 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000529 213.0
HKD1_k127_6117400_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000002128 213.0
HKD1_k127_6117400_2 - - - - 0.00000000000000000000000000000000000000000000000000000001442 210.0
HKD1_k127_6117400_3 - - - - 0.00000000000000000000000000000000000000000000002564 195.0
HKD1_k127_6117400_4 56kDa selenium binding protein (SBP56) K17285 - - 0.00000000000000000000000000000000000000001797 155.0
HKD1_k127_6117400_5 Lysin motif K06194 - - 0.00000000000000000000000000000000000000004166 166.0
HKD1_k127_6117400_6 signal sequence binding K03619 GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 - 0.00000000000000000000000000000000005096 147.0
HKD1_k127_6117400_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000349 136.0
HKD1_k127_6117400_8 Phospholipid methyltransferase - - - 0.000224 48.0
HKD1_k127_6118166_0 Acetyl propionyl-CoA carboxylase, alpha subunit - - - 0.0 1282.0
HKD1_k127_6118166_1 Voltage gated chloride channel K03281 - - 1.651e-214 697.0
HKD1_k127_6118166_10 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 293.0
HKD1_k127_6118166_11 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009834 298.0
HKD1_k127_6118166_12 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59,5.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000002947 249.0
HKD1_k127_6118166_13 Acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000004792 198.0
HKD1_k127_6118166_14 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000154 198.0
HKD1_k127_6118166_15 FabA-like domain K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000001191 164.0
HKD1_k127_6118166_16 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000008961 130.0
HKD1_k127_6118166_17 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000258 84.0
HKD1_k127_6118166_18 - - - - 0.0000001665 58.0
HKD1_k127_6118166_19 4'-phosphopantetheinyl transferase superfamily - - - 0.0000008438 60.0
HKD1_k127_6118166_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 550.0
HKD1_k127_6118166_21 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0005997 43.0
HKD1_k127_6118166_3 transcription factor binding K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 563.0
HKD1_k127_6118166_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 540.0
HKD1_k127_6118166_5 Aldo/keto reductase family K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 448.0
HKD1_k127_6118166_6 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 426.0
HKD1_k127_6118166_7 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 392.0
HKD1_k127_6118166_8 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 397.0
HKD1_k127_6118166_9 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 361.0
HKD1_k127_6123187_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 615.0
HKD1_k127_6123187_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 367.0
HKD1_k127_6123187_2 MaoC like domain K14449 GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.00000000000000000000000000000000000000000000002777 185.0
HKD1_k127_6123187_3 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000004202 87.0
HKD1_k127_6123187_4 Bacterial regulatory proteins, tetR family - - - 0.0000000001637 73.0
HKD1_k127_6151316_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.253e-238 768.0
HKD1_k127_6151316_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000001002 239.0
HKD1_k127_6151316_2 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000004054 235.0
HKD1_k127_6151316_3 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000009883 203.0
HKD1_k127_6151316_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644,K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000007697 187.0
HKD1_k127_6151316_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000003389 81.0
HKD1_k127_6173525_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.625e-222 706.0
HKD1_k127_6173525_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 615.0
HKD1_k127_6173525_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000001657 212.0
HKD1_k127_6173525_11 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000005631 192.0
HKD1_k127_6173525_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000004303 188.0
HKD1_k127_6173525_13 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000004739 180.0
HKD1_k127_6173525_14 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000009375 180.0
HKD1_k127_6173525_15 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000002616 163.0
HKD1_k127_6173525_16 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000003372 177.0
HKD1_k127_6173525_17 PFAM peptidase M22 glycoprotease K01409,K14742 - 2.3.1.234 0.000000000000000000000001499 114.0
HKD1_k127_6173525_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 481.0
HKD1_k127_6173525_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 406.0
HKD1_k127_6173525_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 390.0
HKD1_k127_6173525_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 355.0
HKD1_k127_6173525_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 304.0
HKD1_k127_6173525_7 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002565 281.0
HKD1_k127_6173525_8 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000002981 236.0
HKD1_k127_6173525_9 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000002527 214.0
HKD1_k127_6205471_0 cellulose binding - - - 1.119e-221 693.0
HKD1_k127_6205471_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 573.0
HKD1_k127_6205471_10 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 344.0
HKD1_k127_6205471_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 357.0
HKD1_k127_6205471_12 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000000000000000000005347 199.0
HKD1_k127_6205471_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000002936 162.0
HKD1_k127_6205471_14 YCII-related domain - - - 0.00000000000000000000000000000000000001372 147.0
HKD1_k127_6205471_15 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000000000000000001956 143.0
HKD1_k127_6205471_16 PFAM DoxX family protein K15977 - - 0.00000000000000000000000000000004539 140.0
HKD1_k127_6205471_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000008658 114.0
HKD1_k127_6205471_18 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000007332 103.0
HKD1_k127_6205471_19 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07710 - 2.7.13.3 0.000000000118 62.0
HKD1_k127_6205471_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 561.0
HKD1_k127_6205471_3 Belongs to the sigma-70 factor family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 541.0
HKD1_k127_6205471_4 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 556.0
HKD1_k127_6205471_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 501.0
HKD1_k127_6205471_6 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 483.0
HKD1_k127_6205471_7 quinone binding K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 437.0
HKD1_k127_6205471_8 Selenocysteine-specific translation elongation factor K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 459.0
HKD1_k127_6205471_9 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 413.0
HKD1_k127_6206226_0 Proteasomal ATPase OB/ID domain K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 7.365e-206 657.0
HKD1_k127_6206226_1 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 583.0
HKD1_k127_6206226_10 Proteasome subunit K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007163 278.0
HKD1_k127_6206226_11 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003783 280.0
HKD1_k127_6206226_12 Proteasome subunit K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000007097 277.0
HKD1_k127_6206226_13 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000000000000000000002385 210.0
HKD1_k127_6206226_14 Sulfatase - - - 0.00000000000000000000000000000000000000000000001465 189.0
HKD1_k127_6206226_15 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000001208 134.0
HKD1_k127_6206226_16 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000002217 119.0
HKD1_k127_6206226_17 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000002802 121.0
HKD1_k127_6206226_18 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000004108 119.0
HKD1_k127_6206226_19 HEAT repeat - - - 0.00000000000000000000002739 109.0
HKD1_k127_6206226_2 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 595.0
HKD1_k127_6206226_20 PBS lyase HEAT-like repeat - - - 0.00000000000000000000006058 115.0
HKD1_k127_6206226_21 Pup-like protein K13570 - - 0.00000000001082 68.0
HKD1_k127_6206226_22 SCP-2 sterol transfer family protein - - - 0.0004951 53.0
HKD1_k127_6206226_3 Pup-ligase protein K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 533.0
HKD1_k127_6206226_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 488.0
HKD1_k127_6206226_5 Rod shape-determining protein K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 466.0
HKD1_k127_6206226_6 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 415.0
HKD1_k127_6206226_7 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 351.0
HKD1_k127_6206226_8 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 335.0
HKD1_k127_6206226_9 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 313.0
HKD1_k127_6239409_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 473.0
HKD1_k127_6239409_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000331 182.0
HKD1_k127_6239409_2 transcriptional regulator K18939 - - 0.0000000000000000000000000000000000000000000003067 182.0
HKD1_k127_6305257_0 Heat shock 70 kDa protein K04043 - - 3.558e-210 659.0
HKD1_k127_6305257_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 609.0
HKD1_k127_6305257_10 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000009663 247.0
HKD1_k127_6305257_11 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000001162 270.0
HKD1_k127_6305257_12 Pyrroline-5-carboxylate reductase dimerisation K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000001311 242.0
HKD1_k127_6305257_13 Lactamase, beta 2 - GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0031974,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000211 233.0
HKD1_k127_6305257_14 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000000000000000000000000003211 229.0
HKD1_k127_6305257_15 High-affinity nickel-transport protein K07241 - - 0.0000000000000000000000000000000000000000000000000005958 204.0
HKD1_k127_6305257_16 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000001194 210.0
HKD1_k127_6305257_17 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000007914 175.0
HKD1_k127_6305257_18 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000008478 174.0
HKD1_k127_6305257_19 Type IV pilus assembly protein PilM; K02461 - - 0.00000000000000000000000000000000000000003355 175.0
HKD1_k127_6305257_2 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 592.0
HKD1_k127_6305257_20 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000007893 169.0
HKD1_k127_6305257_21 phosphatase activity K07025 - - 0.00000000000000000000000000000000000001011 156.0
HKD1_k127_6305257_22 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000554 154.0
HKD1_k127_6305257_23 DivIVA protein K04074 - - 0.000000000000000000000000003618 120.0
HKD1_k127_6305257_24 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000451 94.0
HKD1_k127_6305257_25 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - 0.000000000000767 82.0
HKD1_k127_6305257_26 Regulatory protein, FmdB family - - - 0.000000000002954 72.0
HKD1_k127_6305257_27 Belongs to the UPF0235 family K09131 - - 0.000000003136 63.0
HKD1_k127_6305257_28 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000005559 69.0
HKD1_k127_6305257_29 PDZ DHR GLGF domain protein K02452 - - 0.00000001589 67.0
HKD1_k127_6305257_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 468.0
HKD1_k127_6305257_30 General secretion pathway protein K K02460 - - 0.00000001815 67.0
HKD1_k127_6305257_31 Prokaryotic N-terminal methylation motif K02457 - - 0.000003144 59.0
HKD1_k127_6305257_32 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.00006545 55.0
HKD1_k127_6305257_4 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 404.0
HKD1_k127_6305257_5 Bacterial type II/III secretion system short domain K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 406.0
HKD1_k127_6305257_6 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 361.0
HKD1_k127_6305257_7 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 354.0
HKD1_k127_6305257_8 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 339.0
HKD1_k127_6305257_9 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 299.0
HKD1_k127_6349161_0 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 318.0
HKD1_k127_6349161_1 hemolysin activation secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001637 291.0
HKD1_k127_6349161_10 Dodecin K09165 - - 0.000842 51.0
HKD1_k127_6349161_2 haemagglutination activity domain - - - 0.00000000000000000000000000000000000000000000004319 197.0
HKD1_k127_6349161_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000002014 181.0
HKD1_k127_6349161_4 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.0000000000000000000000000000000000000009921 159.0
HKD1_k127_6349161_5 Universal stress protein - - - 0.0000000000000000000004459 110.0
HKD1_k127_6349161_6 Cytidylate kinase-like family - - - 0.00000000000000000000178 108.0
HKD1_k127_6349161_7 regulatory protein TetR - - - 0.00000000000000000576 92.0
HKD1_k127_6349161_8 Putative porin - - - 0.0000000000006834 81.0
HKD1_k127_6349161_9 Dodecin K09165 - - 0.000000000006382 71.0
HKD1_k127_6370868_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 514.0
HKD1_k127_6370868_1 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 422.0
HKD1_k127_6370868_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000013 243.0
HKD1_k127_6370868_3 hydrolase activity, acting on ester bonds K07097 - - 0.00000000000000000000000000000000000000000000001497 184.0
HKD1_k127_6370868_4 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000001827 126.0
HKD1_k127_6370868_5 Belongs to the BolA IbaG family K05527 - - 0.0000000000000001543 93.0
HKD1_k127_6387183_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 561.0
HKD1_k127_6387183_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 475.0
HKD1_k127_6387183_10 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000001121 84.0
HKD1_k127_6387183_11 Cytosol aminopeptidase family, N-terminal domain - - - 0.000000000003122 78.0
HKD1_k127_6387183_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 311.0
HKD1_k127_6387183_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 308.0
HKD1_k127_6387183_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000003983 168.0
HKD1_k127_6387183_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000003513 177.0
HKD1_k127_6387183_6 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000001279 133.0
HKD1_k127_6387183_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000001914 112.0
HKD1_k127_6387183_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000001199 108.0
HKD1_k127_6387183_9 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000006344 94.0
HKD1_k127_6397593_0 Zinc-binding dehydrogenase K17829 - 1.3.1.86 3.794e-210 662.0
HKD1_k127_6397593_1 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 572.0
HKD1_k127_6397593_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006059 295.0
HKD1_k127_6397593_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000001342 191.0
HKD1_k127_6397593_4 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000002504 91.0
HKD1_k127_6447426_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 6.181e-201 636.0
HKD1_k127_6447426_1 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001266 261.0
HKD1_k127_6447426_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000001799 197.0
HKD1_k127_6447426_3 May be involved in the folding of the extracellular lipase during its passage through the periplasm - - - 0.00000000000000000000000000000000000000000000001077 193.0
HKD1_k127_6447426_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000001006 169.0
HKD1_k127_6447426_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000004283 136.0
HKD1_k127_6447426_6 Bacterial membrane protein, YfhO - - - 0.0000001108 64.0
HKD1_k127_6541443_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 618.0
HKD1_k127_6541443_1 cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008732 501.0
HKD1_k127_6541443_10 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000692 296.0
HKD1_k127_6541443_11 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002499 282.0
HKD1_k127_6541443_12 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000006741 205.0
HKD1_k127_6541443_13 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000001714 195.0
HKD1_k127_6541443_14 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000001863 185.0
HKD1_k127_6541443_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000007991 187.0
HKD1_k127_6541443_16 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000009305 173.0
HKD1_k127_6541443_17 Diguanylate cyclase - - - 0.00000000000000000000000000000000000002727 163.0
HKD1_k127_6541443_18 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000005739 123.0
HKD1_k127_6541443_19 beta-lactamase - - - 0.0000000000000000000000000002069 119.0
HKD1_k127_6541443_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 396.0
HKD1_k127_6541443_20 Small multidrug resistance protein K03297 - - 0.0000000000000000000000003918 116.0
HKD1_k127_6541443_21 Sigma-70, region 4 K03088 - - 0.000000000000007848 87.0
HKD1_k127_6541443_22 Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000005939 86.0
HKD1_k127_6541443_23 Periplasmic copper-binding protein (NosD) - - - 0.00000000000009431 84.0
HKD1_k127_6541443_24 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000003579 66.0
HKD1_k127_6541443_25 beta-lactamase - - - 0.00002276 57.0
HKD1_k127_6541443_26 Resolvase - - - 0.00005491 54.0
HKD1_k127_6541443_3 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 387.0
HKD1_k127_6541443_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 368.0
HKD1_k127_6541443_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 359.0
HKD1_k127_6541443_6 Sulfotransferase domain K01014 - 2.8.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 334.0
HKD1_k127_6541443_7 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 339.0
HKD1_k127_6541443_8 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 329.0
HKD1_k127_6541443_9 PFAM O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 295.0
HKD1_k127_6577026_0 cobalamin binding K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1349.0
HKD1_k127_6577026_1 TIGRFAM methylmalonyl-CoA mutase N-terminal domain K01847,K01848 - 5.4.99.2 0.0 1072.0
HKD1_k127_6577026_10 Small GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000001303 241.0
HKD1_k127_6577026_11 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000002418 248.0
HKD1_k127_6577026_12 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000001529 179.0
HKD1_k127_6577026_13 Transcription regulator MerR DNA binding K21902 - - 0.000000000000000000000000371 111.0
HKD1_k127_6577026_14 PFAM VWA containing CoxE family protein K07161 - - 0.0002298 44.0
HKD1_k127_6577026_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 580.0
HKD1_k127_6577026_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 466.0
HKD1_k127_6577026_4 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 392.0
HKD1_k127_6577026_5 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 382.0
HKD1_k127_6577026_6 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 358.0
HKD1_k127_6577026_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 349.0
HKD1_k127_6577026_8 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 336.0
HKD1_k127_6577026_9 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 320.0
HKD1_k127_6582246_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 8.239e-196 625.0
HKD1_k127_6582246_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 417.0
HKD1_k127_6582246_10 - - - - 0.000000000000000000000000000000000000764 160.0
HKD1_k127_6582246_11 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000001662 123.0
HKD1_k127_6582246_12 TIGRFAM cytochrome c oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000001811 116.0
HKD1_k127_6582246_13 Bacterial membrane protein, YfhO - - - 0.0000000000000000007544 100.0
HKD1_k127_6582246_14 FixH - - - 0.0000001945 63.0
HKD1_k127_6582246_2 Heavy metal transport detoxification protein K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 435.0
HKD1_k127_6582246_3 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 297.0
HKD1_k127_6582246_4 TIGRFAM cytochrome c oxidase accessory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 305.0
HKD1_k127_6582246_5 Glycosyltransferase like family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005303 265.0
HKD1_k127_6582246_6 Belongs to the heme-copper respiratory oxidase family K15862 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000001027 252.0
HKD1_k127_6582246_7 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000003892 239.0
HKD1_k127_6582246_8 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000009393 175.0
HKD1_k127_6582246_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000001012 170.0
HKD1_k127_661815_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 352.0
HKD1_k127_661815_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 322.0
HKD1_k127_661815_10 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000001482 246.0
HKD1_k127_661815_11 WYL domain K13572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005517 248.0
HKD1_k127_661815_12 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000592 258.0
HKD1_k127_661815_13 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000001385 241.0
HKD1_k127_661815_14 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006483 254.0
HKD1_k127_661815_15 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000001635 237.0
HKD1_k127_661815_16 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000004122 232.0
HKD1_k127_661815_17 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000002469 218.0
HKD1_k127_661815_18 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000003369 217.0
HKD1_k127_661815_19 glycosyl transferase family 39 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000001417 184.0
HKD1_k127_661815_2 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 329.0
HKD1_k127_661815_20 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000164 162.0
HKD1_k127_661815_21 COG0208 Ribonucleotide reductase, beta subunit - - - 0.00000000000000000000000000000000000000007627 171.0
HKD1_k127_661815_23 Translation initiation factor SUI1 K03113 - - 0.000000000000000000000000000000000005153 149.0
HKD1_k127_661815_24 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000008408 150.0
HKD1_k127_661815_25 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.000000000000000000000000000000004037 137.0
HKD1_k127_661815_26 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000007978 134.0
HKD1_k127_661815_27 CoA-binding protein K06929 - - 0.000000000000000000000000000002774 139.0
HKD1_k127_661815_28 Cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000002716 128.0
HKD1_k127_661815_29 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000002122 119.0
HKD1_k127_661815_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 306.0
HKD1_k127_661815_30 Amino-transferase class IV K00826,K02619 - 2.6.1.42,4.1.3.38 0.0000000000000000224 96.0
HKD1_k127_661815_31 transcriptional regulator, (TetR family - - - 0.0000000000001605 80.0
HKD1_k127_661815_32 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000178 74.0
HKD1_k127_661815_33 - - - - 0.0000000002012 70.0
HKD1_k127_661815_34 - - - - 0.0000000424 61.0
HKD1_k127_661815_35 TIGRFAM PEP-CTERM system TPR-repeat lipoprotein - - - 0.000949 51.0
HKD1_k127_661815_4 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007797 278.0
HKD1_k127_661815_5 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001052 274.0
HKD1_k127_661815_6 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002476 272.0
HKD1_k127_661815_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003757 258.0
HKD1_k127_661815_8 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001009 254.0
HKD1_k127_661815_9 citrate synthase K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000001873 256.0
HKD1_k127_6624582_0 Glycogen debranching enzyme - - - 0.0 1540.0
HKD1_k127_6624582_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.028e-253 811.0
HKD1_k127_6624582_10 Sterol carrier protein - - - 0.0000000005399 66.0
HKD1_k127_6624582_11 Sterol carrier protein - - - 0.000001038 58.0
HKD1_k127_6624582_12 transcriptional regulator, SARP family - - - 0.0004815 49.0
HKD1_k127_6624582_2 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 454.0
HKD1_k127_6624582_3 PFAM Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 300.0
HKD1_k127_6624582_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001433 268.0
HKD1_k127_6624582_5 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000008382 229.0
HKD1_k127_6624582_6 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000001239 193.0
HKD1_k127_6624582_7 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000001357 189.0
HKD1_k127_6624582_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000114 168.0
HKD1_k127_6624582_9 Glycosyltransferase, group 2 family protein - - - 0.0000000000000000000000000007749 124.0
HKD1_k127_6664447_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 584.0
HKD1_k127_6664447_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 562.0
HKD1_k127_6664447_10 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000008756 216.0
HKD1_k127_6664447_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000001502 201.0
HKD1_k127_6664447_12 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000003442 213.0
HKD1_k127_6664447_13 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000002847 204.0
HKD1_k127_6664447_14 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000002531 192.0
HKD1_k127_6664447_15 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000006094 173.0
HKD1_k127_6664447_16 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000002161 173.0
HKD1_k127_6664447_17 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000003181 184.0
HKD1_k127_6664447_18 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000002133 138.0
HKD1_k127_6664447_19 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000274 121.0
HKD1_k127_6664447_2 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 542.0
HKD1_k127_6664447_20 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000001189 124.0
HKD1_k127_6664447_21 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000000000004479 113.0
HKD1_k127_6664447_22 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000003783 121.0
HKD1_k127_6664447_23 protein-(glutamine-N5) methyltransferase activity - - - 0.00000000000000000000000226 117.0
HKD1_k127_6664447_24 Bacterial regulatory proteins, tetR family - - - 0.000000000000000001612 96.0
HKD1_k127_6664447_25 Crp-like helix-turn-helix domain K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000002183 97.0
HKD1_k127_6664447_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 380.0
HKD1_k127_6664447_4 COG0208 Ribonucleotide reductase, beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 318.0
HKD1_k127_6664447_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 300.0
HKD1_k127_6664447_6 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001746 294.0
HKD1_k127_6664447_7 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001482 278.0
HKD1_k127_6664447_8 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000005443 256.0
HKD1_k127_6664447_9 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000005075 263.0
HKD1_k127_6707042_0 Penicillin amidase K01434 - 3.5.1.11 6.092e-226 736.0
HKD1_k127_6707042_1 Aminotransferase class-III K00819 - 2.6.1.13 1.9e-205 652.0
HKD1_k127_6707042_10 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 422.0
HKD1_k127_6707042_11 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 383.0
HKD1_k127_6707042_12 His Kinase A (phospho-acceptor) domain K02484,K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 370.0
HKD1_k127_6707042_13 ABC transporter transmembrane region 2 K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 319.0
HKD1_k127_6707042_14 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 321.0
HKD1_k127_6707042_15 NnrU protein K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 316.0
HKD1_k127_6707042_16 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 304.0
HKD1_k127_6707042_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 296.0
HKD1_k127_6707042_18 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 296.0
HKD1_k127_6707042_19 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006363 290.0
HKD1_k127_6707042_2 PFAM MMPL family K07003 - - 3.249e-201 652.0
HKD1_k127_6707042_20 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007864 290.0
HKD1_k127_6707042_21 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003823 260.0
HKD1_k127_6707042_22 organic phosphonate transport K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000289 256.0
HKD1_k127_6707042_23 PFAM Rhodanese domain protein K03892 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001294 248.0
HKD1_k127_6707042_24 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002351 254.0
HKD1_k127_6707042_25 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000002078 243.0
HKD1_k127_6707042_26 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000003819 241.0
HKD1_k127_6707042_27 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000007294 215.0
HKD1_k127_6707042_28 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000002491 227.0
HKD1_k127_6707042_29 Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.00000000000000000000000000000000000000000000000000000000003608 229.0
HKD1_k127_6707042_3 Pfam Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 596.0
HKD1_k127_6707042_30 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000002629 220.0
HKD1_k127_6707042_31 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000000000000002153 211.0
HKD1_k127_6707042_32 PFAM DinB family protein - - - 0.00000000000000000000000000000000000000000000000000006653 196.0
HKD1_k127_6707042_33 nodulation - - - 0.000000000000000000000000000000000000000000000000001519 206.0
HKD1_k127_6707042_34 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000002533 176.0
HKD1_k127_6707042_35 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000001476 179.0
HKD1_k127_6707042_36 DIE2/ALG10 family - - - 0.0000000000000000000000000000000000000000006363 176.0
HKD1_k127_6707042_37 Methyltransferase domain - - - 0.0000000000000000000000000000000000000001593 158.0
HKD1_k127_6707042_38 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000000000001907 154.0
HKD1_k127_6707042_39 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000006828 153.0
HKD1_k127_6707042_4 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 577.0
HKD1_k127_6707042_40 Dihaem cytochrome c - - - 0.000000000000000000000000000000000001573 152.0
HKD1_k127_6707042_42 Transcriptional regulator K16137 - - 0.0000000000000000000000000000000001294 141.0
HKD1_k127_6707042_43 PFAM Transglycosylase associated protein - - - 0.00000000000000000000000000001209 128.0
HKD1_k127_6707042_44 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000001804 134.0
HKD1_k127_6707042_45 radical SAM domain protein - - - 0.0000000000000000000000000008735 124.0
HKD1_k127_6707042_47 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000008332 115.0
HKD1_k127_6707042_48 Belongs to the ompA family - - - 0.00000000000000000000211 100.0
HKD1_k127_6707042_49 acetyltransferase - - - 0.000000000000000009875 97.0
HKD1_k127_6707042_5 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 559.0
HKD1_k127_6707042_51 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000321 52.0
HKD1_k127_6707042_52 Carbohydrate-selective porin, OprB family K07267 - - 0.0005913 44.0
HKD1_k127_6707042_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 503.0
HKD1_k127_6707042_7 Conserved TM helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 493.0
HKD1_k127_6707042_8 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 493.0
HKD1_k127_6707042_9 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 404.0
HKD1_k127_6727470_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 386.0
HKD1_k127_6727470_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003654 280.0
HKD1_k127_6727470_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000545 265.0
HKD1_k127_6727470_3 Fumarylacetoacetate (FAA) hydrolase family K16164 - 3.7.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000001313 256.0
HKD1_k127_6727470_4 PFAM Isochorismatase - - - 0.00000000000000000000000000000000000000003727 164.0
HKD1_k127_6727470_5 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000001363 168.0
HKD1_k127_6727470_6 TIGRFAM Protein of - - - 0.0000000000000000000000000002232 122.0
HKD1_k127_6727470_7 Aminotransferase class-III - - - 0.00000000000000000004446 97.0
HKD1_k127_6727470_8 Virulence activator alpha C-term - - - 0.00000000000000000008852 96.0
HKD1_k127_6727470_9 signal transduction histidine kinase - - - 0.000001583 59.0
HKD1_k127_6733891_0 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 3.88e-289 900.0
HKD1_k127_6733891_1 AMP-binding enzyme C-terminal domain K00666 - - 2.86e-206 654.0
HKD1_k127_6733891_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 331.0
HKD1_k127_6733891_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 306.0
HKD1_k127_6733891_12 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 299.0
HKD1_k127_6733891_13 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 291.0
HKD1_k127_6733891_14 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 306.0
HKD1_k127_6733891_15 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000005497 253.0
HKD1_k127_6733891_16 Conserved hypothetical ATP binding protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002779 252.0
HKD1_k127_6733891_17 Peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000001335 241.0
HKD1_k127_6733891_18 serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000005681 254.0
HKD1_k127_6733891_19 PD-(D/E)XK nuclease superfamily K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000007677 239.0
HKD1_k127_6733891_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 510.0
HKD1_k127_6733891_20 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000187 244.0
HKD1_k127_6733891_21 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000002863 233.0
HKD1_k127_6733891_22 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000003622 218.0
HKD1_k127_6733891_23 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000104 213.0
HKD1_k127_6733891_24 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000122 211.0
HKD1_k127_6733891_25 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000006657 182.0
HKD1_k127_6733891_26 phospholipase C K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000002421 192.0
HKD1_k127_6733891_27 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000009064 173.0
HKD1_k127_6733891_28 PFAM thioesterase superfamily K07107 - - 0.000000000000000000000008043 106.0
HKD1_k127_6733891_29 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000216 115.0
HKD1_k127_6733891_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 460.0
HKD1_k127_6733891_30 haloacid dehalogenase-like hydrolase K06019 - 3.6.1.1 0.0000000000000000000007077 103.0
HKD1_k127_6733891_31 Belongs to the NUDIX hydrolase family - - - 0.000000000000000000008789 98.0
HKD1_k127_6733891_32 Protein of unknown function (DUF1232) - - - 0.00000000000000000003065 106.0
HKD1_k127_6733891_33 Acyltransferase - - - 0.00000000000000006417 81.0
HKD1_k127_6733891_34 Carboxymuconolactone decarboxylase family - - - 0.000000000000388 79.0
HKD1_k127_6733891_35 NifU-like N terminal domain K04488,K07126,K13819 - - 0.00000000006658 69.0
HKD1_k127_6733891_36 subunit of a heme lyase K02200 - - 0.000000003897 69.0
HKD1_k127_6733891_37 alpha-galactosidase K07407 - 3.2.1.22 0.0000181 58.0
HKD1_k127_6733891_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 438.0
HKD1_k127_6733891_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 383.0
HKD1_k127_6733891_6 nitronate monooxygenase activity K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 353.0
HKD1_k127_6733891_7 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 346.0
HKD1_k127_6733891_8 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 329.0
HKD1_k127_6733891_9 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 344.0
HKD1_k127_674388_0 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 501.0
HKD1_k127_674388_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 317.0
HKD1_k127_674388_2 PFAM catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000004327 279.0
HKD1_k127_674388_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000006398 182.0
HKD1_k127_674388_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000004918 186.0
HKD1_k127_674388_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000001731 175.0
HKD1_k127_674388_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.000000000000000000000000000000003705 131.0
HKD1_k127_674388_8 Protein of unknown function (DUF1285) - - - 0.0002972 50.0
HKD1_k127_6750354_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 329.0
HKD1_k127_6750354_1 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 289.0
HKD1_k127_6750354_2 Lactoylglutathione lyase - - - 0.0000000000000000000000000000000000000000000000000746 184.0
HKD1_k127_6753959_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 599.0
HKD1_k127_6753959_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 401.0
HKD1_k127_6753959_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 377.0
HKD1_k127_6753959_3 DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000145 257.0
HKD1_k127_6753959_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000003968 192.0
HKD1_k127_6753959_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000001885 144.0
HKD1_k127_6753959_6 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000003047 87.0
HKD1_k127_6753959_7 DnaD domain protein - - - 0.000000000276 74.0
HKD1_k127_6753959_8 Loader and inhibitor of phage G40P - - - 0.0000000013 67.0
HKD1_k127_675704_0 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 606.0
HKD1_k127_675704_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 465.0
HKD1_k127_675704_10 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000001985 127.0
HKD1_k127_675704_11 Luciferase-like monooxygenase - - - 0.00000000000000000000004374 114.0
HKD1_k127_675704_12 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000002885 98.0
HKD1_k127_675704_13 Putative adhesin - - - 0.000000000001288 78.0
HKD1_k127_675704_14 - - - - 0.00002414 53.0
HKD1_k127_675704_2 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 295.0
HKD1_k127_675704_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 294.0
HKD1_k127_675704_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007812 270.0
HKD1_k127_675704_5 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000004777 178.0
HKD1_k127_675704_6 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000007779 168.0
HKD1_k127_675704_7 Rhomboid family K09650 - 3.4.21.105 0.0000000000000000000000000000000000000005839 160.0
HKD1_k127_675704_8 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.0000000000000000000000000000000000000008494 163.0
HKD1_k127_675704_9 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000000000000000000006183 152.0
HKD1_k127_6772624_0 Belongs to the DEAD box helicase family K05592,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 396.0
HKD1_k127_6772624_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 295.0
HKD1_k127_6772624_2 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001629 278.0
HKD1_k127_6772624_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000001078 91.0
HKD1_k127_6822124_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 7.283e-248 785.0
HKD1_k127_6822124_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 9.413e-225 717.0
HKD1_k127_6822124_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 499.0
HKD1_k127_6822124_3 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 409.0
HKD1_k127_6822124_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001804 288.0
HKD1_k127_6822124_5 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000002273 194.0
HKD1_k127_6822124_6 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000002292 159.0
HKD1_k127_6822124_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000002688 125.0
HKD1_k127_6822124_8 Domain of unknown function (DUF4281) - - - 0.00000000000000003365 87.0
HKD1_k127_6822124_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000003058 92.0
HKD1_k127_6951973_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 519.0
HKD1_k127_6951973_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 460.0
HKD1_k127_6951973_10 PFAM glycosyl transferase family 9 K02841 - - 0.00000000000000000000000000000000000000000000000003676 202.0
HKD1_k127_6951973_11 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000662 171.0
HKD1_k127_6951973_12 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000004354 161.0
HKD1_k127_6951973_13 SMART Immunoglobulin C2 type - - - 0.00000000000000000003922 107.0
HKD1_k127_6951973_14 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000002062 89.0
HKD1_k127_6951973_15 PFAM Outer membrane K06142 - - 0.00000000000005274 78.0
HKD1_k127_6951973_16 kinase activity - - - 0.0000000000001516 83.0
HKD1_k127_6951973_2 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 325.0
HKD1_k127_6951973_3 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003174 288.0
HKD1_k127_6951973_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000001127 267.0
HKD1_k127_6951973_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002416 257.0
HKD1_k127_6951973_6 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000001308 274.0
HKD1_k127_6951973_7 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000004211 241.0
HKD1_k127_6951973_8 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000135 241.0
HKD1_k127_6951973_9 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000007538 219.0
HKD1_k127_6984714_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 520.0
HKD1_k127_6984714_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000006042 250.0
HKD1_k127_6984714_2 E1-E2 ATPase K01547 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000002003 198.0
HKD1_k127_6984714_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11383 - 2.7.13.3 0.0007096 52.0
HKD1_k127_7004073_0 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000006166 194.0
HKD1_k127_7004073_1 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000001975 177.0
HKD1_k127_7004073_2 Sugar efflux transporter for intercellular exchange - - - 0.000000000000000000000000000001555 136.0
HKD1_k127_7004073_3 Belongs to the ompA family K03640 GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032153,GO:0044425,GO:0044462,GO:0044464,GO:0051301,GO:0071944,GO:0098552 - 0.0000000000000528 80.0
HKD1_k127_700762_0 COG2124 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 447.0
HKD1_k127_700762_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 380.0
HKD1_k127_700762_2 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 306.0
HKD1_k127_700762_3 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000000001457 123.0
HKD1_k127_700762_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000005285 126.0
HKD1_k127_700762_5 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000003389 103.0
HKD1_k127_700762_6 Lipase maturation factor - - - 0.000000000000007538 76.0
HKD1_k127_700762_7 - - - - 0.0000000000002161 79.0
HKD1_k127_7040398_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 498.0
HKD1_k127_7040398_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 293.0
HKD1_k127_7040398_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000001337 252.0
HKD1_k127_7040398_3 RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000009661 114.0
HKD1_k127_7040398_4 Protein of unknown function (DUF1329) - - - 0.0000000000000000000001684 109.0
HKD1_k127_7040398_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000002561 66.0
HKD1_k127_7040398_6 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor - - - 0.0000001084 63.0
HKD1_k127_7043262_0 AMP-binding enzyme C-terminal domain K00666 - - 5.264e-205 650.0
HKD1_k127_7043262_1 4Fe-4S dicluster domain K00184 - - 3.91e-202 666.0
HKD1_k127_7043262_10 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000001969 183.0
HKD1_k127_7043262_11 Protein of unknown function (DUF3341) - - - 0.0000000000000000000004978 113.0
HKD1_k127_7043262_12 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000006419 102.0
HKD1_k127_7043262_13 Belongs to the P(II) protein family K04751 - - 0.00000000000000001195 88.0
HKD1_k127_7043262_15 Metallo-beta-lactamase superfamily - - - 0.0000000000000006403 92.0
HKD1_k127_7043262_16 PFAM Rhomboid family protein - - - 0.00000000000466 79.0
HKD1_k127_7043262_17 PFAM peptidase - - - 0.000005335 59.0
HKD1_k127_7043262_2 Psort location CytoplasmicMembrane, score 10.00 K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 505.0
HKD1_k127_7043262_3 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 474.0
HKD1_k127_7043262_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 438.0
HKD1_k127_7043262_5 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 387.0
HKD1_k127_7043262_6 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 356.0
HKD1_k127_7043262_7 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000004479 240.0
HKD1_k127_7043262_8 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000048 219.0
HKD1_k127_7043262_9 NUBPL iron-transfer P-loop NTPase - - - 0.0000000000000000000000000000000000000000000000003063 193.0
HKD1_k127_7045499_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 615.0
HKD1_k127_7045499_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 567.0
HKD1_k127_7045499_10 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000009519 232.0
HKD1_k127_7045499_11 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000001054 205.0
HKD1_k127_7045499_12 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000004948 218.0
HKD1_k127_7045499_13 protein transport - - - 0.00000000000000000000000000000000000000000000000000003699 201.0
HKD1_k127_7045499_14 Domain of unknown function (DUF3291) - - - 0.00000000000000000000000000000000000000000000000001279 186.0
HKD1_k127_7045499_15 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000004636 179.0
HKD1_k127_7045499_16 chain release factor K15034 - - 0.0000000000000000000000000000000002189 141.0
HKD1_k127_7045499_17 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000000000000000000003027 128.0
HKD1_k127_7045499_18 - - - - 0.00000000000000000000000000005997 129.0
HKD1_k127_7045499_19 Cupin domain - - - 0.000000000000000000000000000753 114.0
HKD1_k127_7045499_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K14257 - 1.14.19.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 464.0
HKD1_k127_7045499_20 - - - - 0.0000000000000000000000003329 111.0
HKD1_k127_7045499_21 - - - - 0.000000000000004507 82.0
HKD1_k127_7045499_22 Putative inner membrane exporter, YdcZ K09936 - - 0.00000000000223 76.0
HKD1_k127_7045499_25 Bacterial protein of unknown function (DUF922) - - - 0.000001826 60.0
HKD1_k127_7045499_3 Belongs to the thiolase family K00626 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 407.0
HKD1_k127_7045499_4 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 390.0
HKD1_k127_7045499_5 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 289.0
HKD1_k127_7045499_6 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000419 278.0
HKD1_k127_7045499_7 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002609 287.0
HKD1_k127_7045499_8 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007984 253.0
HKD1_k127_7045499_9 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000002582 235.0
HKD1_k127_7063427_0 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001277 248.0
HKD1_k127_7063427_1 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000481 197.0
HKD1_k127_7063427_2 inositol monophosphate 1-phosphatase activity K01092,K05602,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.000000000000000000000000000000000000000002527 168.0
HKD1_k127_7063427_3 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.000000002736 63.0
HKD1_k127_7073945_0 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 613.0
HKD1_k127_7073945_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 404.0
HKD1_k127_7073945_10 IMP dehydrogenase activity - - - 0.000000000000000000000000003538 119.0
HKD1_k127_7073945_11 - - - - 0.000000000000000000814 91.0
HKD1_k127_7073945_13 energy transducer activity K03832 - - 0.0000005744 63.0
HKD1_k127_7073945_14 Membrane-bound serine protease (ClpP class) K07403 - - 0.0002533 49.0
HKD1_k127_7073945_15 Oxidoreductase - - - 0.0009149 53.0
HKD1_k127_7073945_2 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 394.0
HKD1_k127_7073945_3 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 381.0
HKD1_k127_7073945_4 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000138 229.0
HKD1_k127_7073945_5 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.00000000000000000000000000000000000000000000001857 183.0
HKD1_k127_7073945_6 Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB K02014,K16092 - - 0.000000000000000000000000000000000000000000004865 187.0
HKD1_k127_7073945_7 - - - - 0.00000000000000000000000000000000000000000006925 168.0
HKD1_k127_7073945_8 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000231 166.0
HKD1_k127_7073945_9 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000000003397 146.0
HKD1_k127_7077876_0 metallopeptidase activity - - - 7.593e-247 790.0
HKD1_k127_7077876_1 Putative zinc binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 613.0
HKD1_k127_7077876_10 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000003067 251.0
HKD1_k127_7077876_11 Oligosaccharide biosynthesis protein Alg14 like - - - 0.0000000000000000000000000000000000000000000001002 175.0
HKD1_k127_7077876_12 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000001342 125.0
HKD1_k127_7077876_13 - - - - 0.000000000000000002895 91.0
HKD1_k127_7077876_14 - - - - 0.000000000000002283 87.0
HKD1_k127_7077876_15 PFAM Dual specificity protein phosphatase K14165 - 3.1.3.16,3.1.3.48 0.00000000000333 76.0
HKD1_k127_7077876_2 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 467.0
HKD1_k127_7077876_3 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 457.0
HKD1_k127_7077876_4 Nucleotidyl transferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 398.0
HKD1_k127_7077876_5 C-methyltransferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 377.0
HKD1_k127_7077876_6 C-methyltransferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 363.0
HKD1_k127_7077876_7 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 341.0
HKD1_k127_7077876_8 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 338.0
HKD1_k127_7077876_9 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000109 275.0
HKD1_k127_708414_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 421.0
HKD1_k127_708414_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 416.0
HKD1_k127_708414_2 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 329.0
HKD1_k127_708414_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 311.0
HKD1_k127_708414_4 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000008628 260.0
HKD1_k127_708414_5 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000008856 124.0
HKD1_k127_708414_6 Histone deacetylase domain - - - 0.0000000194 59.0
HKD1_k127_7093661_0 Methionine synthase K00548 - 2.1.1.13 0.0 1832.0
HKD1_k127_7093661_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 621.0
HKD1_k127_7093661_10 lysyltransferase activity K07027 - - 0.00000000000000000000000001744 123.0
HKD1_k127_7093661_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 503.0
HKD1_k127_7093661_3 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 327.0
HKD1_k127_7093661_4 cytochrome P450 K16593 GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.14.14.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 312.0
HKD1_k127_7093661_5 TIGRFAM hopanoid biosynthesis associated protein HpnK - - - 0.00000000000000000000000000000000000000000000000000000000003725 216.0
HKD1_k127_7093661_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000001579 170.0
HKD1_k127_7093661_7 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000009112 168.0
HKD1_k127_7093661_8 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000002327 128.0
HKD1_k127_7093661_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K14331 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0071771 1.16.3.1,4.1.99.5 0.000000000000000000000000000002324 130.0
HKD1_k127_7106091_0 Luciferase-like monooxygenase - - - 7.093e-210 665.0
HKD1_k127_7106091_1 Na melibiose symporter and related transporters K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 471.0
HKD1_k127_7106091_2 dioxygenase K11159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 362.0
HKD1_k127_7106091_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 313.0
HKD1_k127_7106091_4 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 299.0
HKD1_k127_713330_0 Molydopterin dinucleotide binding domain - - - 3.51e-292 915.0
HKD1_k127_713330_1 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 597.0
HKD1_k127_713330_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002598 255.0
HKD1_k127_713330_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000005934 224.0
HKD1_k127_713330_12 - - - - 0.00000000000000000000000000000000000000000000000000000000002048 211.0
HKD1_k127_713330_13 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000002999 177.0
HKD1_k127_713330_14 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000009679 155.0
HKD1_k127_713330_15 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000005876 126.0
HKD1_k127_713330_16 - - - - 0.000000000000000000000000007727 123.0
HKD1_k127_713330_17 transcriptional regulator - - - 0.00000000000000000002642 102.0
HKD1_k127_713330_18 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000005406 102.0
HKD1_k127_713330_19 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000004577 76.0
HKD1_k127_713330_2 cytochrome P450 K05917 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008398,GO:0016125,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0032451,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0055114,GO:0070988,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901615 1.14.13.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 578.0
HKD1_k127_713330_20 PDZ DHR GLGF domain protein - - - 0.00007165 55.0
HKD1_k127_713330_3 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 475.0
HKD1_k127_713330_4 nitrite transmembrane transporter activity K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 425.0
HKD1_k127_713330_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 412.0
HKD1_k127_713330_6 BFD-like [2Fe-2S] binding domain K00362 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 399.0
HKD1_k127_713330_7 beta-galactosidase activity K01190,K17624 - 3.2.1.23,3.2.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 306.0
HKD1_k127_713330_8 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001831 282.0
HKD1_k127_713330_9 IQR COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004024 277.0
HKD1_k127_7165743_0 Tetratricopeptide repeats - - - 0.00000004535 65.0
HKD1_k127_718704_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 3.053e-280 874.0
HKD1_k127_718704_1 Sugar (and other) transporter K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 519.0
HKD1_k127_718704_10 PFAM secretion protein HlyD family protein K03543 - - 0.000000000000000000000000000000000000000000000000000000002942 212.0
HKD1_k127_718704_11 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000002619 203.0
HKD1_k127_718704_12 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000609 171.0
HKD1_k127_718704_13 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000002713 162.0
HKD1_k127_718704_14 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000001035 172.0
HKD1_k127_718704_2 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 470.0
HKD1_k127_718704_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 452.0
HKD1_k127_718704_4 Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 428.0
HKD1_k127_718704_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 305.0
HKD1_k127_718704_6 hydrolase activity, hydrolyzing O-glycosyl compounds K00689 GO:0005575,GO:0005576 2.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 330.0
HKD1_k127_718704_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000007101 244.0
HKD1_k127_718704_8 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001557 243.0
HKD1_k127_718704_9 proteins of the AP superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000002794 241.0
HKD1_k127_720823_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 537.0
HKD1_k127_720823_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 394.0
HKD1_k127_720823_10 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.0000000000000000000000000000000000000881 153.0
HKD1_k127_720823_11 PFAM PHA accumulation regulator DNA-binding protein - - - 0.0000000000000000004457 95.0
HKD1_k127_720823_12 helix_turn_helix, mercury resistance - - - 0.000000000000000006223 89.0
HKD1_k127_720823_13 thiolester hydrolase activity K06889 - - 0.00000000000000003776 91.0
HKD1_k127_720823_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000005309 83.0
HKD1_k127_720823_15 DNA-templated transcription, initiation K03088 - - 0.000000000000002225 84.0
HKD1_k127_720823_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 311.0
HKD1_k127_720823_3 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 296.0
HKD1_k127_720823_4 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003335 248.0
HKD1_k127_720823_5 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000008641 245.0
HKD1_k127_720823_6 ATP cone domain K05715 - - 0.0000000000000000000000000000000000000000000000000000000000000000009973 242.0
HKD1_k127_720823_7 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000001639 258.0
HKD1_k127_720823_8 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000006479 193.0
HKD1_k127_720823_9 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000721 177.0
HKD1_k127_7208402_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 551.0
HKD1_k127_7208402_1 transport system involved in gliding motility, auxiliary K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004981 294.0
HKD1_k127_7208402_10 Bacterial regulatory proteins, tetR family K13770 - - 0.0000000000000000000000000000000000005717 160.0
HKD1_k127_7208402_11 - - - - 0.0000000000000000000000002732 113.0
HKD1_k127_7208402_12 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000009092 108.0
HKD1_k127_7208402_13 Polymer-forming cytoskeletal - - - 0.00000000000000000002079 98.0
HKD1_k127_7208402_14 Domain of unknown function (DUF4340) - - - 0.0000000000000001512 93.0
HKD1_k127_7208402_15 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000003204 78.0
HKD1_k127_7208402_16 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.00005411 55.0
HKD1_k127_7208402_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000462 273.0
HKD1_k127_7208402_3 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003104 263.0
HKD1_k127_7208402_4 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000001469 265.0
HKD1_k127_7208402_5 hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000407 246.0
HKD1_k127_7208402_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000001882 207.0
HKD1_k127_7208402_7 Peptidase, S54 (Rhomboid) family - - - 0.0000000000000000000000000000000000000000000000000000003235 218.0
HKD1_k127_7208402_8 Molybdenum cofactor biosynthesis K03638,K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000002166 177.0
HKD1_k127_7208402_9 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000000000000009649 164.0
HKD1_k127_7210446_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1457.0
HKD1_k127_7210446_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 9.334e-245 786.0
HKD1_k127_7210446_10 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 470.0
HKD1_k127_7210446_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 443.0
HKD1_k127_7210446_12 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 451.0
HKD1_k127_7210446_13 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 443.0
HKD1_k127_7210446_14 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 426.0
HKD1_k127_7210446_15 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 426.0
HKD1_k127_7210446_16 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 392.0
HKD1_k127_7210446_17 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 374.0
HKD1_k127_7210446_18 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 383.0
HKD1_k127_7210446_19 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 349.0
HKD1_k127_7210446_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 8.678e-219 706.0
HKD1_k127_7210446_20 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 316.0
HKD1_k127_7210446_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 302.0
HKD1_k127_7210446_22 alpha beta - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 335.0
HKD1_k127_7210446_23 COGs COG0531 Amino acid transporter K03294,K20265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 304.0
HKD1_k127_7210446_24 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002079 293.0
HKD1_k127_7210446_25 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002872 261.0
HKD1_k127_7210446_26 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000003195 218.0
HKD1_k127_7210446_27 Ribosomal protein L16p/L10e K02878 - - 0.00000000000000000000000000000000000000000000000000000000002302 209.0
HKD1_k127_7210446_28 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002003 198.0
HKD1_k127_7210446_29 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002509 209.0
HKD1_k127_7210446_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 4.496e-208 655.0
HKD1_k127_7210446_30 Ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000003882 200.0
HKD1_k127_7210446_31 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000005539 199.0
HKD1_k127_7210446_32 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000006619 201.0
HKD1_k127_7210446_33 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000001554 211.0
HKD1_k127_7210446_34 glycosyl transferase family 39 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000453 212.0
HKD1_k127_7210446_35 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000002215 180.0
HKD1_k127_7210446_36 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000008949 177.0
HKD1_k127_7210446_37 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000002915 193.0
HKD1_k127_7210446_38 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000006013 154.0
HKD1_k127_7210446_39 Glutathione peroxidase - - - 0.000000000000000000000000000000000000001128 153.0
HKD1_k127_7210446_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 591.0
HKD1_k127_7210446_40 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000001355 157.0
HKD1_k127_7210446_41 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000002818 144.0
HKD1_k127_7210446_42 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000002782 135.0
HKD1_k127_7210446_43 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000003684 120.0
HKD1_k127_7210446_44 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000004871 116.0
HKD1_k127_7210446_45 major facilitator superfamily - - - 0.0000000000000000000000001333 121.0
HKD1_k127_7210446_46 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000725 113.0
HKD1_k127_7210446_47 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000002201 105.0
HKD1_k127_7210446_48 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000001798 76.0
HKD1_k127_7210446_49 PFAM ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000002278 76.0
HKD1_k127_7210446_5 aminotransferase K14261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 542.0
HKD1_k127_7210446_50 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000008145 72.0
HKD1_k127_7210446_51 Thiol disulfide interchange protein - - - 0.000000000004162 75.0
HKD1_k127_7210446_52 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000001486 69.0
HKD1_k127_7210446_53 PAP2 superfamily K19302 - 3.6.1.27 0.0000001179 63.0
HKD1_k127_7210446_54 Putative prokaryotic signal transducing protein - - - 0.0000001893 61.0
HKD1_k127_7210446_55 Protein involved in meta-pathway of phenol degradation - - - 0.00000807 59.0
HKD1_k127_7210446_56 PFAM Sporulation domain protein K03749 - - 0.00006132 56.0
HKD1_k127_7210446_6 TIGRFAM arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 511.0
HKD1_k127_7210446_7 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 518.0
HKD1_k127_7210446_8 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 477.0
HKD1_k127_7210446_9 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 477.0
HKD1_k127_7235902_0 DEAD DEAH box helicase - - - 8.522e-273 865.0
HKD1_k127_7235902_1 Superfamily II DNA RNA helicases, SNF2 family - - - 7.771e-256 821.0
HKD1_k127_7235902_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 502.0
HKD1_k127_7235902_3 EVE domain - - - 0.00000000000000000000000000000000000000000000000002501 204.0
HKD1_k127_7261267_0 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 351.0
HKD1_k127_7261267_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005998 303.0
HKD1_k127_7261267_2 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.000000000000000000000000000000000000000004076 178.0
HKD1_k127_7261267_3 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000005355 135.0
HKD1_k127_7261267_4 Tetratricopeptide repeat - - - 0.000000000000000000000337 113.0
HKD1_k127_7305605_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.016e-229 736.0
HKD1_k127_7305605_1 ATP synthase alpha/beta chain, C terminal domain K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 569.0
HKD1_k127_7305605_10 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000002482 242.0
HKD1_k127_7305605_11 Two component transcriptional regulator, winged helix family K07657 - - 0.000000000000000000000000000000000000000000000001968 186.0
HKD1_k127_7305605_12 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000002061 182.0
HKD1_k127_7305605_13 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000002141 149.0
HKD1_k127_7305605_14 sugar phosphate isomerase involved in capsule formation K06041 - 5.3.1.13 0.0000000000000000000000000000000005067 153.0
HKD1_k127_7305605_15 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000007698 141.0
HKD1_k127_7305605_16 domain, Protein - - - 0.0000000000000000000000000002917 129.0
HKD1_k127_7305605_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000002071 110.0
HKD1_k127_7305605_18 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000005013 108.0
HKD1_k127_7305605_19 DNA uptake protein and related DNA-binding proteins K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000003624 79.0
HKD1_k127_7305605_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 550.0
HKD1_k127_7305605_20 Protein containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.0000000000006774 73.0
HKD1_k127_7305605_21 Belongs to the DapA family K01639,K01714 - 4.1.3.3,4.3.3.7 0.0001441 56.0
HKD1_k127_7305605_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 451.0
HKD1_k127_7305605_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 379.0
HKD1_k127_7305605_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01906 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47,6.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 368.0
HKD1_k127_7305605_6 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002851 285.0
HKD1_k127_7305605_7 Amidohydrolase family K01443,K16786,K16787 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000009006 251.0
HKD1_k127_7305605_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000008449 245.0
HKD1_k127_7305605_9 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000002627 237.0
HKD1_k127_732800_0 glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 518.0
HKD1_k127_732800_1 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 475.0
HKD1_k127_732800_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 364.0
HKD1_k127_732800_3 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 349.0
HKD1_k127_732800_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000008565 241.0
HKD1_k127_732800_6 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000001458 211.0
HKD1_k127_732800_7 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000003902 196.0
HKD1_k127_732800_8 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000002342 101.0
HKD1_k127_732800_9 Tetratricopeptide repeat - - - 0.0000000001183 71.0
HKD1_k127_7353823_0 PFAM AMP-dependent synthetase K00666 - - 5.01e-217 691.0
HKD1_k127_7353823_1 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 520.0
HKD1_k127_7353823_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 501.0
HKD1_k127_7353823_3 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 394.0
HKD1_k127_7353823_4 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 314.0
HKD1_k127_7353823_5 Methylmuconolactone methyl-isomerase - - - 0.0000000000000000000000000000000000000000132 156.0
HKD1_k127_7353823_6 Selenoprotein B glycine betaine sarcosine D-proline reductase K10794 - 1.21.4.1 0.000000000000000000000000001112 116.0
HKD1_k127_7353823_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000003589 104.0
HKD1_k127_7410005_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 434.0
HKD1_k127_7410005_1 PFAM PhoH family protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 366.0
HKD1_k127_7410005_10 DNA polymerase III K02340 - 2.7.7.7 0.000000000000001028 89.0
HKD1_k127_7410005_11 GGDEF domain K03413 - - 0.0000000000002516 74.0
HKD1_k127_7410005_12 Tetratricopeptide repeat - - - 0.00000000003792 76.0
HKD1_k127_7410005_13 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.0001756 51.0
HKD1_k127_7410005_14 Binds directly to 16S ribosomal RNA K02968 - - 0.0004551 54.0
HKD1_k127_7410005_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 350.0
HKD1_k127_7410005_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 319.0
HKD1_k127_7410005_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002282 287.0
HKD1_k127_7410005_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000141 283.0
HKD1_k127_7410005_6 HEAT repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000287 244.0
HKD1_k127_7410005_7 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000000008134 179.0
HKD1_k127_7410005_8 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000001525 176.0
HKD1_k127_7410005_9 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000001222 121.0
HKD1_k127_7460615_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1401.0
HKD1_k127_7460615_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1195.0
HKD1_k127_7460615_10 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 397.0
HKD1_k127_7460615_11 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 373.0
HKD1_k127_7460615_12 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 366.0
HKD1_k127_7460615_13 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 305.0
HKD1_k127_7460615_14 Acyl-CoA thioesterase K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000002505 234.0
HKD1_k127_7460615_15 MgtC family - - - 0.00000000000000000000000000000000000000000000000000000003122 222.0
HKD1_k127_7460615_16 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000003981 196.0
HKD1_k127_7460615_17 repeat protein - - - 0.000000000000000000000000000000000000000000002646 190.0
HKD1_k127_7460615_18 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000001698 162.0
HKD1_k127_7460615_19 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000001767 136.0
HKD1_k127_7460615_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 6.801e-283 887.0
HKD1_k127_7460615_20 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000006609 141.0
HKD1_k127_7460615_21 repeat protein - - - 0.0000000000000000000000003222 124.0
HKD1_k127_7460615_22 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000009459 98.0
HKD1_k127_7460615_23 Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000004966 92.0
HKD1_k127_7460615_3 4-hydroxyphenylacetate 3-hydroxylase K14534 - 4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 632.0
HKD1_k127_7460615_4 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 563.0
HKD1_k127_7460615_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 548.0
HKD1_k127_7460615_6 Cytochrome P450 K20497 - 1.14.15.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 531.0
HKD1_k127_7460615_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 505.0
HKD1_k127_7460615_8 Biotin carboxylase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 472.0
HKD1_k127_7460615_9 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 464.0
HKD1_k127_7482778_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 546.0
HKD1_k127_7482778_1 alcohol dehydrogenase K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 528.0
HKD1_k127_7482778_10 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000002682 261.0
HKD1_k127_7482778_11 Type II secretory pathway, component ExeA K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004252 252.0
HKD1_k127_7482778_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007598 268.0
HKD1_k127_7482778_13 Mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000001945 261.0
HKD1_k127_7482778_14 transferase K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000001299 232.0
HKD1_k127_7482778_15 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000007847 207.0
HKD1_k127_7482778_16 eight transmembrane protein EpsH - - - 0.000000000000000000000000000000000000000000000000347 199.0
HKD1_k127_7482778_17 NUBPL iron-transfer P-loop NTPase K00903 - 2.7.10.2 0.00000000000000000000000000000000000000000003116 174.0
HKD1_k127_7482778_18 Lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000001543 176.0
HKD1_k127_7482778_19 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000002597 154.0
HKD1_k127_7482778_2 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 484.0
HKD1_k127_7482778_20 Transcriptional regulator, Crp Fnr family K10914 - - 0.00000000000000000000000000000000000007769 151.0
HKD1_k127_7482778_21 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000005624 137.0
HKD1_k127_7482778_3 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 458.0
HKD1_k127_7482778_4 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 423.0
HKD1_k127_7482778_5 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 407.0
HKD1_k127_7482778_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 389.0
HKD1_k127_7482778_7 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 366.0
HKD1_k127_7482778_8 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 344.0
HKD1_k127_7482778_9 PFAM NAD dependent epimerase dehydratase family K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 318.0
HKD1_k127_7493661_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2014.0
HKD1_k127_7493661_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 458.0
HKD1_k127_7548046_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 548.0
HKD1_k127_7548046_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 536.0
HKD1_k127_7548046_10 Essential cell division protein K03589 - - 0.0001178 54.0
HKD1_k127_7548046_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 417.0
HKD1_k127_7548046_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 337.0
HKD1_k127_7548046_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000002492 251.0
HKD1_k127_7548046_5 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000002188 235.0
HKD1_k127_7548046_6 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000003093 236.0
HKD1_k127_7548046_7 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000001986 222.0
HKD1_k127_7548046_8 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000007829 205.0
HKD1_k127_7548046_9 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000002116 70.0
HKD1_k127_7562695_0 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008515 272.0
HKD1_k127_7562695_1 3-demethylubiquinone-9 3-O-methyltransferase activity K15257,K16868,K18827,K20444 - 2.1.1.265,2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000008202 249.0
HKD1_k127_7562695_2 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000005488 216.0
HKD1_k127_7562695_3 YCII-related domain - - - 0.00000000000000000000000000000000000000003218 161.0
HKD1_k127_7562695_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.00000000000000000000000000000000000002331 155.0
HKD1_k127_7562695_6 depolymerase - - - 0.0001681 54.0
HKD1_k127_7583655_0 alpha-glucan phosphorylase K00688 - 2.4.1.1 2.259e-224 716.0
HKD1_k127_7583655_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.667e-221 715.0
HKD1_k127_7583655_10 Binding-protein-dependent transport system inner membrane component K02050,K15552,K15554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 305.0
HKD1_k127_7583655_11 Abc transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002494 300.0
HKD1_k127_7583655_12 TIGRFAM Tyrosine recombinase XerD K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000119 265.0
HKD1_k127_7583655_13 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008003 254.0
HKD1_k127_7583655_14 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000001387 263.0
HKD1_k127_7583655_15 pfam abc1 K03688 - - 0.00000000000000000000000000000000000000000000000000000000000002122 237.0
HKD1_k127_7583655_16 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000006281 222.0
HKD1_k127_7583655_17 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000009817 224.0
HKD1_k127_7583655_18 ErfK YbiS YcfS YnhG family protein K16291 - - 0.000000000000000000000000000000000000000000000000000000002908 214.0
HKD1_k127_7583655_19 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000002103 205.0
HKD1_k127_7583655_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 1.467e-204 669.0
HKD1_k127_7583655_20 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000003076 190.0
HKD1_k127_7583655_21 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000001829 177.0
HKD1_k127_7583655_22 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000008905 167.0
HKD1_k127_7583655_23 diguanylate cyclase - - - 0.00000000000000000000000000000000000008749 164.0
HKD1_k127_7583655_24 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000002725 138.0
HKD1_k127_7583655_25 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000000007204 118.0
HKD1_k127_7583655_26 - - - - 0.000000000000000000000001984 113.0
HKD1_k127_7583655_27 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000009456 109.0
HKD1_k127_7583655_28 peptidoglycan-binding protein, lysm - - - 0.00000000000000000000133 96.0
HKD1_k127_7583655_3 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.223e-202 678.0
HKD1_k127_7583655_30 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000005706 67.0
HKD1_k127_7583655_31 Lipopolysaccharide assembly protein A domain K08992 - - 0.00003431 51.0
HKD1_k127_7583655_4 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 526.0
HKD1_k127_7583655_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 409.0
HKD1_k127_7583655_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 336.0
HKD1_k127_7583655_7 amino acid-binding ACT domain protein K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 356.0
HKD1_k127_7583655_8 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 347.0
HKD1_k127_7583655_9 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 330.0
HKD1_k127_762261_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01907 - 6.2.1.16 2.337e-263 827.0
HKD1_k127_762261_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 512.0
HKD1_k127_762261_10 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000027 175.0
HKD1_k127_762261_11 - - - - 0.0000000000000000004501 100.0
HKD1_k127_762261_12 Outer membrane lipoprotein-sorting protein - - - 0.000000000169 72.0
HKD1_k127_762261_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 404.0
HKD1_k127_762261_3 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 334.0
HKD1_k127_762261_4 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 314.0
HKD1_k127_762261_5 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006359 293.0
HKD1_k127_762261_6 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002497 273.0
HKD1_k127_762261_7 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001118 257.0
HKD1_k127_762261_9 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000000000000000000006094 173.0
HKD1_k127_7637073_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 0.0 1403.0
HKD1_k127_7637073_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1021.0
HKD1_k127_7637073_10 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000003436 243.0
HKD1_k127_7637073_11 PFAM ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000006735 215.0
HKD1_k127_7637073_12 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000006126 193.0
HKD1_k127_7637073_13 TPM domain K06872 - - 0.00000000000000000000000000000002263 141.0
HKD1_k127_7637073_14 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000001896 138.0
HKD1_k127_7637073_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 606.0
HKD1_k127_7637073_3 4-alpha-glucanotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 605.0
HKD1_k127_7637073_4 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 518.0
HKD1_k127_7637073_5 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 486.0
HKD1_k127_7637073_6 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 435.0
HKD1_k127_7637073_7 PFAM ABC transporter related K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006719 265.0
HKD1_k127_7637073_8 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000003086 259.0
HKD1_k127_7637073_9 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000001164 237.0
HKD1_k127_7661815_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 528.0
HKD1_k127_7661815_1 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 378.0
HKD1_k127_7661815_10 Phosphopantetheine attachment site - - - 0.000001856 54.0
HKD1_k127_7661815_11 maltose O-acetyltransferase activity - - - 0.000003193 59.0
HKD1_k127_7661815_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003157 306.0
HKD1_k127_7661815_3 - - - - 0.000000000000000000000000000000000000000000000000000000176 210.0
HKD1_k127_7661815_4 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000003623 207.0
HKD1_k127_7661815_5 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000008376 166.0
HKD1_k127_7661815_6 transferase activity, transferring glycosyl groups K07011,K20444 - - 0.0000000000000002812 92.0
HKD1_k127_7661815_8 Glycosyl transferases group 1 - - - 0.000000000003948 78.0
HKD1_k127_7661815_9 COG3307 Lipid A core - O-antigen ligase and related enzymes K18814 - - 0.0000002172 63.0
HKD1_k127_773246_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.877e-199 664.0
HKD1_k127_773246_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 421.0
HKD1_k127_773246_10 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000001216 156.0
HKD1_k127_773246_11 - - - - 0.00000000000000000000000000001679 124.0
HKD1_k127_773246_12 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000006195 121.0
HKD1_k127_773246_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000001046 83.0
HKD1_k127_773246_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 408.0
HKD1_k127_773246_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 340.0
HKD1_k127_773246_4 Catalyzes the synthesis of activated sulfate K00860 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016740,GO:0016772,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001183 286.0
HKD1_k127_773246_5 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008288 265.0
HKD1_k127_773246_6 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000002165 248.0
HKD1_k127_773246_7 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000006498 243.0
HKD1_k127_773246_8 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000004971 217.0
HKD1_k127_773246_9 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000002854 190.0
HKD1_k127_7733493_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 413.0
HKD1_k127_7733493_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 404.0
HKD1_k127_7857264_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.068e-205 652.0
HKD1_k127_7857264_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 569.0
HKD1_k127_7857264_2 PFAM Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000005723 212.0
HKD1_k127_7857264_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000005715 91.0
HKD1_k127_7857264_4 - - - - 0.0000001394 65.0
HKD1_k127_7857264_5 Domain of unknown function (DUF4388) - - - 0.000001146 61.0
HKD1_k127_7875658_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 9.131e-235 742.0
HKD1_k127_7875658_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007118 497.0
HKD1_k127_7875658_10 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000005498 230.0
HKD1_k127_7875658_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000001095 232.0
HKD1_k127_7875658_12 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000003065 227.0
HKD1_k127_7875658_13 phosphatidylcholine synthase activity K01004,K17103 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24,2.7.8.8 0.000000000000000000000000000000000000000000000009958 183.0
HKD1_k127_7875658_16 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000003367 160.0
HKD1_k127_7875658_17 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000007035 134.0
HKD1_k127_7875658_18 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008289,GO:0009405,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0030312,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0043177,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050662,GO:0050789,GO:0050794,GO:0051704,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204 2.3.1.61 0.00000000000000000000000007647 109.0
HKD1_k127_7875658_19 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000003901 99.0
HKD1_k127_7875658_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 428.0
HKD1_k127_7875658_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000197 86.0
HKD1_k127_7875658_21 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000001506 82.0
HKD1_k127_7875658_22 Cytochrome c - - - 0.000000002779 62.0
HKD1_k127_7875658_23 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000001086 64.0
HKD1_k127_7875658_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 421.0
HKD1_k127_7875658_4 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 411.0
HKD1_k127_7875658_5 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 386.0
HKD1_k127_7875658_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 366.0
HKD1_k127_7875658_7 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 327.0
HKD1_k127_7875658_8 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001426 271.0
HKD1_k127_7875658_9 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001645 269.0
HKD1_k127_799457_0 HI0933-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 438.0
HKD1_k127_799457_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 334.0
HKD1_k127_799457_10 PEP-CTERM motif - - - 0.0000000000000000000000000001048 124.0
HKD1_k127_799457_11 PFAM YeeE YedE family (DUF395) K07112 - - 0.000000000000000000001416 106.0
HKD1_k127_799457_12 NUDIX domain - - - 0.000000000000000000002439 107.0
HKD1_k127_799457_13 - K07112 - - 0.0000000000000000001339 96.0
HKD1_k127_799457_15 Histidine kinase - - - 0.0000000000003669 81.0
HKD1_k127_799457_16 GPR1/FUN34/yaaH family K07034 - - 0.0000000001346 70.0
HKD1_k127_799457_17 - - - - 0.0000000009437 70.0
HKD1_k127_799457_2 protein conserved in bacteria K09990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 317.0
HKD1_k127_799457_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000148 287.0
HKD1_k127_799457_4 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000109 291.0
HKD1_k127_799457_5 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000399 256.0
HKD1_k127_799457_6 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009691 246.0
HKD1_k127_799457_7 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000003351 127.0
HKD1_k127_799457_8 PAS fold - - - 0.000000000000000000000000000005894 132.0
HKD1_k127_799457_9 Putative stress-induced transcription regulator - - - 0.0000000000000000000000000000139 126.0
HKD1_k127_8034630_0 Peptidase family C69 K14358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 304.0
HKD1_k127_8034630_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001921 282.0
HKD1_k127_8034630_2 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000003192 87.0
HKD1_k127_8034630_3 Helix-turn-helix domain - - - 0.00006391 50.0
HKD1_k127_903579_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 491.0
HKD1_k127_903579_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 444.0
HKD1_k127_903579_2 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 406.0
HKD1_k127_903579_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 366.0
HKD1_k127_903579_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 325.0
HKD1_k127_903579_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007287 277.0
HKD1_k127_903579_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000281 241.0
HKD1_k127_903579_7 imidazoleglycerol-phosphate dehydratase activity K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000021 233.0
HKD1_k127_903579_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000002764 219.0
HKD1_k127_903579_9 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000005475 92.0
HKD1_k127_938634_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K19594 - - 0.0 1395.0
HKD1_k127_938634_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008204 484.0
HKD1_k127_938634_2 outer membrane efflux - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 464.0
HKD1_k127_938634_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K19595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 327.0
HKD1_k127_938634_4 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00004,K00008,K05351,K08322 - 1.1.1.14,1.1.1.303,1.1.1.380,1.1.1.4,1.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001261 260.0
HKD1_k127_938634_5 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000001023 104.0