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Overview

ID MAG01705
Name HKD1_bin.16
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Vicinamibacteria
Order Fen-336
Family Fen-336
Genus DATKME01
Species
Assembly information
Completeness (%) 60.14
Contamination (%) 1.84
GC content (%) 72.0
N50 (bp) 8,869
Genome size (bp) 3,037,668

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2585

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1010821_0 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 3.817e-216 680.0
HKD1_k127_1010821_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 607.0
HKD1_k127_1010821_2 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 553.0
HKD1_k127_1010821_3 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 530.0
HKD1_k127_1010821_4 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 350.0
HKD1_k127_1010821_5 peptidase S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001697 276.0
HKD1_k127_1010821_6 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000001202 213.0
HKD1_k127_1011713_1 Protein of unknown function, DUF481 K07283 - - 0.0000000000652 75.0
HKD1_k127_1011713_2 Forkhead associated domain K01990,K21397 - - 0.00000004913 61.0
HKD1_k127_1016032_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 2.205e-280 891.0
HKD1_k127_1016032_1 Cytochrome C assembly protein - - - 2.856e-239 762.0
HKD1_k127_1016032_2 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008718 290.0
HKD1_k127_1016032_3 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000009767 237.0
HKD1_k127_1016032_4 RmuC family K09760 - - 0.00000000000000000000000000000000000000004164 176.0
HKD1_k127_1016032_5 B3/4 domain - - - 0.000000000000000000000000000000003182 141.0
HKD1_k127_1016032_6 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000005312 130.0
HKD1_k127_1034411_0 phosphorelay signal transduction system K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000085 434.0
HKD1_k127_1034411_1 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000009141 266.0
HKD1_k127_1034411_2 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000001813 203.0
HKD1_k127_1041250_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 563.0
HKD1_k127_1041250_1 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000005697 91.0
HKD1_k127_1049010_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 530.0
HKD1_k127_1049010_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 525.0
HKD1_k127_1049010_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000008585 200.0
HKD1_k127_1049010_3 Hydrogenase maturation protease K03605 - - 0.00000000000000000000004347 110.0
HKD1_k127_1049010_4 ABC-2 type transporter - - - 0.000000000003243 77.0
HKD1_k127_1049010_5 - - - - 0.00000000004324 75.0
HKD1_k127_1049010_6 Transcriptional regulatory protein, C terminal K07667 - - 0.000001177 61.0
HKD1_k127_1061299_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 508.0
HKD1_k127_1061299_1 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001674 245.0
HKD1_k127_1061299_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000004335 72.0
HKD1_k127_1087995_0 beta-galactosidase activity - - - 6.623e-313 1003.0
HKD1_k127_1087995_1 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 541.0
HKD1_k127_1087995_2 Belongs to the glycosyl hydrolase 18 family K01183 - 3.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 330.0
HKD1_k127_1087995_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000001812 193.0
HKD1_k127_1087995_4 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0000000000000000000000000000000000009979 141.0
HKD1_k127_1087995_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000004028 107.0
HKD1_k127_1087995_6 PspC domain - - - 0.0000000000000001023 90.0
HKD1_k127_1087995_7 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000003898 76.0
HKD1_k127_1087995_8 FHA domain - - - 0.00000000005776 72.0
HKD1_k127_1087995_9 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000001287 57.0
HKD1_k127_1089421_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 473.0
HKD1_k127_1089421_1 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001189 265.0
HKD1_k127_1089421_2 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000001846 244.0
HKD1_k127_1089421_3 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000000001519 88.0
HKD1_k127_1089421_4 zinc metalloprotease K11749 - - 0.0002709 51.0
HKD1_k127_1093324_0 carboxylic acid catabolic process K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 538.0
HKD1_k127_1093324_1 glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 469.0
HKD1_k127_1093324_10 PFAM Bacterial regulatory protein, arsR family - - - 0.000000003804 70.0
HKD1_k127_1093324_2 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 427.0
HKD1_k127_1093324_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001213 256.0
HKD1_k127_1093324_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000005017 205.0
HKD1_k127_1093324_5 Mannosyltransferase (PIG-V) - - - 0.00000000000000000000000000000000000009074 161.0
HKD1_k127_1093324_6 Lipoprotein K05811 - - 0.0000000000000000000000000000000002384 152.0
HKD1_k127_1093324_7 - - - - 0.00000000000000000709 91.0
HKD1_k127_1093324_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000002898 91.0
HKD1_k127_1093324_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000002641 87.0
HKD1_k127_1098906_0 Belongs to the DegT DnrJ EryC1 family K02805,K13010,K18653 - 2.6.1.102,2.6.1.104,2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 331.0
HKD1_k127_1098906_1 PFAM Glycosyl transferase family 2 K07027 - - 0.0000000000000000000000000000004389 141.0
HKD1_k127_1098906_2 Bacterial membrane protein, YfhO - - - 0.0000000000000000000001523 115.0
HKD1_k127_1098906_3 Bacterial transferase hexapeptide repeat protein - - - 0.00000000008269 74.0
HKD1_k127_1117777_0 transcription factor binding K02584 - - 2.615e-210 664.0
HKD1_k127_1117777_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 562.0
HKD1_k127_1117777_10 Ammonium Transporter K03320 - - 0.000000000000003561 76.0
HKD1_k127_1117777_11 GDSL-like Lipase/Acylhydrolase - - - 0.000000000003679 79.0
HKD1_k127_1117777_12 Domain of unknown function (DUF4412) - - - 0.000000003901 67.0
HKD1_k127_1117777_13 von Willebrand factor, type A K12511 - - 0.000000003901 67.0
HKD1_k127_1117777_14 Putative zinc-finger - - - 0.0002043 53.0
HKD1_k127_1117777_2 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000172 243.0
HKD1_k127_1117777_3 ggdef domain - - - 0.0000000000000000000000000000000000000000000000000000000004283 217.0
HKD1_k127_1117777_4 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000002687 178.0
HKD1_k127_1117777_5 von Willebrand factor, type A - - - 0.0000000000000000000000000000000004042 150.0
HKD1_k127_1117777_7 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000505 123.0
HKD1_k127_1117777_8 PFAM Membrane protein of K08972 - - 0.0000000000000003056 90.0
HKD1_k127_1117777_9 - - - - 0.0000000000000003503 88.0
HKD1_k127_1135467_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 1.974e-196 623.0
HKD1_k127_1135467_1 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 600.0
HKD1_k127_1135467_10 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000000000000000000001403 192.0
HKD1_k127_1135467_11 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000007763 166.0
HKD1_k127_1135467_12 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000002386 123.0
HKD1_k127_1135467_13 Hydrogenase maturation protease - - - 0.0000000000000000000007918 107.0
HKD1_k127_1135467_14 Polysulphide reductase, NrfD - - - 0.000000000000001354 77.0
HKD1_k127_1135467_15 Initiates the rapid degradation of small, acid-soluble proteins during spore germination - - - 0.00000000005776 72.0
HKD1_k127_1135467_2 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 556.0
HKD1_k127_1135467_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 488.0
HKD1_k127_1135467_4 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 403.0
HKD1_k127_1135467_5 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 368.0
HKD1_k127_1135467_6 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 380.0
HKD1_k127_1135467_7 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 344.0
HKD1_k127_1135467_8 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002729 284.0
HKD1_k127_1135467_9 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000008276 210.0
HKD1_k127_113906_0 Involved in the tonB-independent uptake of proteins K03641 - - 3.771e-284 893.0
HKD1_k127_113906_1 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 1.626e-257 842.0
HKD1_k127_113906_2 Chlorophyllase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007932 607.0
HKD1_k127_113906_3 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 519.0
HKD1_k127_113906_4 Transcriptional regulator with HTH domain and aminotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 338.0
HKD1_k127_113906_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 319.0
HKD1_k127_113906_6 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.00000000000000000003988 92.0
HKD1_k127_113906_7 - - - - 0.0000000002503 73.0
HKD1_k127_1143745_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 328.0
HKD1_k127_1143745_1 ABC-2 type transporter K01990,K21397 - - 0.00000000001199 77.0
HKD1_k127_1150486_0 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 505.0
HKD1_k127_1150486_1 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 347.0
HKD1_k127_1150486_2 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 295.0
HKD1_k127_1150486_3 Inward rectifier potassium channel K08715 - - 0.000000000000000000000000000000000000000000000000000000003243 209.0
HKD1_k127_1150486_4 mannosylglycerate metabolic process K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.00000000000000000000000000000000000000000000389 186.0
HKD1_k127_1150486_5 transmembrane transport - - - 0.000000000000000000000000000001666 129.0
HKD1_k127_1160932_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 363.0
HKD1_k127_1162177_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 427.0
HKD1_k127_1162177_1 Ppx GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 383.0
HKD1_k127_1162177_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 332.0
HKD1_k127_1162177_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001042 253.0
HKD1_k127_1162177_4 Exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000004725 93.0
HKD1_k127_1162177_5 CHAD - - - 0.0000007222 60.0
HKD1_k127_117760_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000003198 210.0
HKD1_k127_117760_1 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000146 146.0
HKD1_k127_1219483_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 568.0
HKD1_k127_1219483_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 326.0
HKD1_k127_1219483_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000002716 210.0
HKD1_k127_1219483_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000002211 196.0
HKD1_k127_1219483_4 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000004072 143.0
HKD1_k127_1219483_5 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00004682 47.0
HKD1_k127_1219483_6 - - - - 0.0001028 47.0
HKD1_k127_1230179_0 ABC transporter K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 424.0
HKD1_k127_1230179_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008746 389.0
HKD1_k127_1230179_2 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 401.0
HKD1_k127_1230179_3 zinc metallopeptidase K07054 - - 0.00000000000000000002308 99.0
HKD1_k127_123030_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000001019 126.0
HKD1_k127_123030_1 competence protein - - - 0.0000000000000000000000000001566 131.0
HKD1_k127_123030_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000003234 61.0
HKD1_k127_1237892_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1768.0
HKD1_k127_1237892_1 Penicillin amidase K01434 - 3.5.1.11 1.373e-220 712.0
HKD1_k127_1237892_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 439.0
HKD1_k127_1237892_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003539 284.0
HKD1_k127_1237892_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000002836 186.0
HKD1_k127_1257332_0 MacB-like periplasmic core domain K02003,K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001495 274.0
HKD1_k127_1257332_1 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000001945 173.0
HKD1_k127_1257332_2 lipoprotein localization to outer membrane K02004 - - 0.000001373 50.0
HKD1_k127_127913_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 2.572e-233 728.0
HKD1_k127_127913_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 529.0
HKD1_k127_127913_2 major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000481 310.0
HKD1_k127_127913_3 PFAM Enoyl-CoA hydratase isomerase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000001709 236.0
HKD1_k127_127913_4 Protease prsW family - - - 0.00000000000000000000000000000000004765 147.0
HKD1_k127_1281347_0 FGGY family of carbohydrate kinases, C-terminal domain K00853 - 2.7.1.16 2.056e-233 735.0
HKD1_k127_1281347_1 Alcohol dehydrogenase GroES-like domain K00004,K00008,K00098 - 1.1.1.14,1.1.1.264,1.1.1.303,1.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 368.0
HKD1_k127_1281347_2 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 322.0
HKD1_k127_1281347_3 4-epimerase K03077 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0043167,GO:0043169,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046872,GO:0046914,GO:0071704,GO:1901575 5.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002149 269.0
HKD1_k127_1281347_4 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000003536 225.0
HKD1_k127_129295_0 AMP-binding enzyme K12508 - 6.2.1.34 6.867e-207 661.0
HKD1_k127_129295_1 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 2.023e-196 635.0
HKD1_k127_129295_2 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 530.0
HKD1_k127_129295_3 3-carboxy-cis,cis-muconate cycloisomerase K01857 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 466.0
HKD1_k127_129295_4 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 365.0
HKD1_k127_129295_5 protocatechuate 3,4-dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 345.0
HKD1_k127_129295_6 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 301.0
HKD1_k127_129295_7 - - - - 0.0000000000000000000000000000000000000000000000001526 182.0
HKD1_k127_129295_8 phosphorelay signal transduction system - - - 0.000000000000002779 85.0
HKD1_k127_129295_9 Alpha beta hydrolase K01055 - 3.1.1.24 0.000000000000003115 83.0
HKD1_k127_1298234_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 470.0
HKD1_k127_1298234_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 439.0
HKD1_k127_1298234_2 Phosphotransferase enzyme family K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 370.0
HKD1_k127_1298234_3 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000001542 209.0
HKD1_k127_1298234_4 prohibitin homologues K07192 - - 0.00000000000000000000000000000000000002641 160.0
HKD1_k127_1298234_5 TIGRFAM TonB family K03832 - - 0.00000000000000000000000000001433 130.0
HKD1_k127_1318329_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.177e-196 629.0
HKD1_k127_1318329_1 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 415.0
HKD1_k127_1318329_2 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 359.0
HKD1_k127_1318329_3 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000004615 180.0
HKD1_k127_1318329_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000444 68.0
HKD1_k127_1340731_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 617.0
HKD1_k127_1375866_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 1.678e-296 935.0
HKD1_k127_1375866_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 609.0
HKD1_k127_1375866_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 390.0
HKD1_k127_1375866_3 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 363.0
HKD1_k127_1393322_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007778 483.0
HKD1_k127_1393322_1 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 313.0
HKD1_k127_1393322_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.0000000000000001847 94.0
HKD1_k127_1393322_3 - - - - 0.0000000000001493 83.0
HKD1_k127_1393322_4 bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding K03092 - - 0.0002547 45.0
HKD1_k127_1400101_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 396.0
HKD1_k127_1400101_1 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003196 278.0
HKD1_k127_1400101_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000001774 180.0
HKD1_k127_1400101_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000006692 115.0
HKD1_k127_1408225_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 468.0
HKD1_k127_1408225_1 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 378.0
HKD1_k127_1408225_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 375.0
HKD1_k127_1408225_3 GTPase activity K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 299.0
HKD1_k127_1408225_4 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000003458 214.0
HKD1_k127_1408225_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000003301 204.0
HKD1_k127_1408225_6 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000001207 147.0
HKD1_k127_1408225_7 diguanylate cyclase - - - 0.000000000000000000000000000006384 121.0
HKD1_k127_1408225_8 NUDIX domain - - - 0.000000000000000000004038 102.0
HKD1_k127_1408225_9 PFAM Methyltransferase type 11 - - - 0.0000000004606 70.0
HKD1_k127_1421588_0 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 566.0
HKD1_k127_1421588_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 443.0
HKD1_k127_1421588_11 NeuB family K03856 - 2.5.1.54 0.000171 44.0
HKD1_k127_1421588_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 341.0
HKD1_k127_1421588_3 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 306.0
HKD1_k127_1421588_4 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000001604 245.0
HKD1_k127_1421588_5 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000001238 223.0
HKD1_k127_1421588_6 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000003814 207.0
HKD1_k127_1421588_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000007404 192.0
HKD1_k127_1421588_8 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000921 173.0
HKD1_k127_1421588_9 - - - - 0.000000001557 60.0
HKD1_k127_1449923_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00138 - 1.2.1.3,1.2.1.8 0.0 1173.0
HKD1_k127_1449923_1 deoxyribose-phosphate aldolase activity K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 482.0
HKD1_k127_1449923_2 gluconolactonase activity K01053 GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 388.0
HKD1_k127_1449923_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000004422 216.0
HKD1_k127_1449923_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000001099 200.0
HKD1_k127_1449923_5 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000000000000638 127.0
HKD1_k127_1449923_6 aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000003183 104.0
HKD1_k127_1449923_7 PBS lyase HEAT-like repeat - - - 0.0000000001969 69.0
HKD1_k127_145974_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.818e-209 682.0
HKD1_k127_145974_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009735 492.0
HKD1_k127_145974_2 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 403.0
HKD1_k127_145974_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 322.0
HKD1_k127_145974_4 Regulatory protein, FmdB - - - 0.0000000000000000000001259 102.0
HKD1_k127_145974_5 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.0000001476 64.0
HKD1_k127_1460979_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.657e-312 977.0
HKD1_k127_1460979_1 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 479.0
HKD1_k127_1460979_2 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001473 274.0
HKD1_k127_1460979_3 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000002694 222.0
HKD1_k127_1460979_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000001756 119.0
HKD1_k127_1460979_5 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.0000000000000000001704 102.0
HKD1_k127_1460979_6 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00000000000002158 83.0
HKD1_k127_1475997_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 605.0
HKD1_k127_1475997_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 464.0
HKD1_k127_1475997_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001866 294.0
HKD1_k127_1475997_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007117 261.0
HKD1_k127_1475997_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000001863 259.0
HKD1_k127_1475997_5 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000000000000059 174.0
HKD1_k127_1480695_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.363e-287 896.0
HKD1_k127_1480695_1 Amidohydrolase family - - - 9.06e-199 649.0
HKD1_k127_1480695_10 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000917 220.0
HKD1_k127_1480695_11 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000004327 218.0
HKD1_k127_1480695_12 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000001415 201.0
HKD1_k127_1480695_13 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000002182 196.0
HKD1_k127_1480695_15 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000008851 166.0
HKD1_k127_1480695_16 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000123 157.0
HKD1_k127_1480695_17 von Willebrand factor, type A K07114 - - 0.00000000000000000000000008566 119.0
HKD1_k127_1480695_18 lyase activity - - - 0.0000000000000000007976 102.0
HKD1_k127_1480695_19 Polymer-forming cytoskeletal - - - 0.000000003703 63.0
HKD1_k127_1480695_2 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 596.0
HKD1_k127_1480695_20 GDSL-like Lipase/Acylhydrolase - - - 0.00000001402 68.0
HKD1_k127_1480695_21 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0003731 52.0
HKD1_k127_1480695_3 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 605.0
HKD1_k127_1480695_4 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 592.0
HKD1_k127_1480695_5 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 365.0
HKD1_k127_1480695_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 348.0
HKD1_k127_1480695_7 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 326.0
HKD1_k127_1480695_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000007466 239.0
HKD1_k127_1480695_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000008737 226.0
HKD1_k127_1482833_0 AAA domain - - - 4.148e-282 889.0
HKD1_k127_1482833_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 561.0
HKD1_k127_1482833_2 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 389.0
HKD1_k127_1482833_3 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002024 268.0
HKD1_k127_1482833_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000003571 222.0
HKD1_k127_1482833_5 Nicotinamide mononucleotide transporter K03811 - - 0.000000000000000000000000000000000000000000000000435 181.0
HKD1_k127_1482833_6 spore germination K07790 - - 0.0000000000000000000000000000000000000000000001478 181.0
HKD1_k127_1482833_7 AAA domain - - - 0.0000000000000000000000000000000000001297 156.0
HKD1_k127_1482833_8 phosphate ion binding - - - 0.00000000000000000001162 96.0
HKD1_k127_1482833_9 Glycosyl transferase, family 2 - - - 0.000004807 51.0
HKD1_k127_1490692_0 malic protein domain protein K00027 - 1.1.1.38 2.449e-250 784.0
HKD1_k127_1490692_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 3.246e-222 705.0
HKD1_k127_1490692_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 514.0
HKD1_k127_1490692_3 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.00000000000000000000000000000000000000000000000000000009695 207.0
HKD1_k127_1490692_4 Histidine kinase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000003571 194.0
HKD1_k127_1490692_5 Diguanylate cyclase K21084 - 2.7.7.65 0.0000000000000000000000000000000000000000748 175.0
HKD1_k127_1495521_0 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000002096 246.0
HKD1_k127_1495521_1 PFAM Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000005331 140.0
HKD1_k127_1507591_0 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 400.0
HKD1_k127_1507591_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.00000000000000000000000000000000000000000000000000000000000000000000006413 245.0
HKD1_k127_1507591_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001068 192.0
HKD1_k127_1507591_3 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000002727 108.0
HKD1_k127_1507591_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000005091 65.0
HKD1_k127_1524201_0 phosphorelay signal transduction system K02481,K07713,K07714 - - 3.599e-217 681.0
HKD1_k127_1524201_1 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 534.0
HKD1_k127_1524201_10 Protein of unknown function (DUF4019) - - - 0.00000000000000000000000000000001173 137.0
HKD1_k127_1524201_11 metallopeptidase activity K06974 - - 0.0000000000000000000000000000001845 143.0
HKD1_k127_1524201_12 - - - - 0.0000000000000000001343 90.0
HKD1_k127_1524201_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 529.0
HKD1_k127_1524201_3 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 519.0
HKD1_k127_1524201_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 455.0
HKD1_k127_1524201_5 PFAM Alkyl hydroperoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 441.0
HKD1_k127_1524201_6 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 426.0
HKD1_k127_1524201_7 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 377.0
HKD1_k127_1524201_8 glycine decarboxylation via glycine cleavage system K02437 - - 0.000000000000000000000000000000000000000000000000000000000000000000001043 245.0
HKD1_k127_1524201_9 - - - - 0.0000000000000000000000000000000000000000000000000005889 205.0
HKD1_k127_1550994_0 OPT oligopeptide transporter protein - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 548.0
HKD1_k127_1550994_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 312.0
HKD1_k127_1550994_2 dTDP biosynthetic process K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000591 249.0
HKD1_k127_1550994_3 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000005803 242.0
HKD1_k127_1550994_4 Mur ligase middle domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000002289 207.0
HKD1_k127_1550994_5 Yqey-like protein K09117 - - 0.00000000000000000000000000000000004223 140.0
HKD1_k127_1550994_7 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.000000000000000000000003749 119.0
HKD1_k127_1572113_0 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 3.28e-316 986.0
HKD1_k127_1572113_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 422.0
HKD1_k127_1572113_2 Surface antigen K07277,K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009454 273.0
HKD1_k127_1572113_3 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000002592 214.0
HKD1_k127_1572113_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000002848 192.0
HKD1_k127_1572113_5 Penicillinase repressor - - - 0.00000000000000000000000000000000000002964 147.0
HKD1_k127_1572113_6 BlaR1 peptidase M56 - - - 0.0000000000000000000000000000000001123 153.0
HKD1_k127_1572113_7 nitric oxide dioxygenase activity - - - 0.00000000000000000000000000006517 127.0
HKD1_k127_1616006_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 416.0
HKD1_k127_1616006_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 347.0
HKD1_k127_1616006_10 peptidyl-tyrosine sulfation - - - 0.0000000000006089 78.0
HKD1_k127_1616006_11 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000009393 77.0
HKD1_k127_1616006_12 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000001588 66.0
HKD1_k127_1616006_2 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 300.0
HKD1_k127_1616006_3 Aldose 1-epimerase K01792 - 5.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 293.0
HKD1_k127_1616006_4 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003921 276.0
HKD1_k127_1616006_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000005085 239.0
HKD1_k127_1616006_6 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000008569 233.0
HKD1_k127_1616006_7 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000001563 139.0
HKD1_k127_1616006_8 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000000000001263 146.0
HKD1_k127_1616006_9 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000005201 119.0
HKD1_k127_1647127_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 419.0
HKD1_k127_1647127_1 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 375.0
HKD1_k127_1647127_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 373.0
HKD1_k127_1647127_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 296.0
HKD1_k127_1647127_4 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000003539 246.0
HKD1_k127_1647127_5 Hypothetical glycosyl hydrolase 6 - - - 0.0000000000000000000000000000008181 125.0
HKD1_k127_1677220_0 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0 1027.0
HKD1_k127_1677220_1 Bacterial transcriptional activator domain - - - 2.091e-252 818.0
HKD1_k127_1677220_10 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000000001564 211.0
HKD1_k127_1677220_11 PFAM inositol monophosphatase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000008151 189.0
HKD1_k127_1677220_12 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000001444 184.0
HKD1_k127_1677220_13 Thioesterase K07107 - - 0.000000000000000000000000000000000000001917 151.0
HKD1_k127_1677220_14 Penicillinase repressor - - - 0.0000000000000000000000000000000002257 135.0
HKD1_k127_1677220_15 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000001351 104.0
HKD1_k127_1677220_16 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000001294 97.0
HKD1_k127_1677220_17 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000009352 81.0
HKD1_k127_1677220_2 Berberine and berberine like - - - 4.809e-219 699.0
HKD1_k127_1677220_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.759e-216 703.0
HKD1_k127_1677220_4 Glycosyl hydrolases family 31 - - - 6.852e-206 678.0
HKD1_k127_1677220_5 Glycosyl hydrolase family 30 TIM-barrel domain K01201 - 3.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 606.0
HKD1_k127_1677220_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01707 - 4.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 338.0
HKD1_k127_1677220_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002259 274.0
HKD1_k127_1677220_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003051 284.0
HKD1_k127_1677220_9 Peptidase M56, BlaR1 - - - 0.0000000000000000000000000000000000000000000000000000000000004961 233.0
HKD1_k127_1683437_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 566.0
HKD1_k127_1683437_1 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000003389 250.0
HKD1_k127_1683437_2 Domain of unknown function DUF11 - - - 0.00000000000003801 87.0
HKD1_k127_1683437_3 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.00000002136 67.0
HKD1_k127_1683437_4 Bacterial membrane protein, YfhO - - - 0.0000001407 60.0
HKD1_k127_1700674_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 528.0
HKD1_k127_1700674_1 PFAM Helicase conserved C-terminal domain K17675 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 430.0
HKD1_k127_1706864_0 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 509.0
HKD1_k127_1706864_1 Leukotriene A4 hydrolase, C-terminal K01254 GO:0003674,GO:0003824,GO:0004177,GO:0004301,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016801,GO:0016803,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 502.0
HKD1_k127_1706864_10 response regulator receiver K13599 - - 0.000001334 61.0
HKD1_k127_1706864_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 360.0
HKD1_k127_1706864_3 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 346.0
HKD1_k127_1706864_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001104 278.0
HKD1_k127_1706864_5 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000004067 225.0
HKD1_k127_1706864_6 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000002533 140.0
HKD1_k127_1706864_7 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000001857 81.0
HKD1_k127_1706864_8 Histidine kinase - - - 0.000000000002391 71.0
HKD1_k127_1706864_9 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000001078 63.0
HKD1_k127_170749_0 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 4.684e-300 932.0
HKD1_k127_170749_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 602.0
HKD1_k127_170749_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 419.0
HKD1_k127_170749_3 Male sterility protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 428.0
HKD1_k127_170749_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 380.0
HKD1_k127_170749_5 PFAM N-acetylneuraminic acid synthase K01654,K15898,K18430 - 2.5.1.101,2.5.1.56,2.5.1.97 0.0000000000000000000000000006326 125.0
HKD1_k127_1805273_0 histidine kinase HAMP region domain protein K07641 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 565.0
HKD1_k127_1805273_1 Sulfatase K01137 - 3.1.6.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 456.0
HKD1_k127_1805273_2 WD40-like Beta Propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 419.0
HKD1_k127_1805273_3 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 331.0
HKD1_k127_1805273_4 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000002593 186.0
HKD1_k127_1805273_5 peptidase S41 - - - 0.000000000000000000000000000000000435 144.0
HKD1_k127_1805273_6 beta-galactosidase activity - - - 0.0000000000000000000000001383 123.0
HKD1_k127_1805273_7 - - - - 0.00000000005991 66.0
HKD1_k127_181839_0 PFAM N-acetylneuraminic acid synthase K01654 - 2.5.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 469.0
HKD1_k127_181839_1 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 308.0
HKD1_k127_181839_2 Domain of unknown function (DUF4184) - - - 0.000000000000000000000000006569 121.0
HKD1_k127_181839_3 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate - - - 0.00000000000000000163 88.0
HKD1_k127_1825824_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 454.0
HKD1_k127_1825824_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 383.0
HKD1_k127_185630_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 387.0
HKD1_k127_185630_1 Branched-chain amino acid transport system / permease component K10440,K10553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 378.0
HKD1_k127_185630_2 transport system, ATPase K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 301.0
HKD1_k127_1861995_0 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 442.0
HKD1_k127_1861995_1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 290.0
HKD1_k127_1861995_2 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002917 290.0
HKD1_k127_1861995_3 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004711 278.0
HKD1_k127_1861995_4 LysM domain - - - 0.00000000000000000000000000000000000000000000000006821 186.0
HKD1_k127_1910163_0 protein conserved in bacteria K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 369.0
HKD1_k127_1910163_1 PFAM Protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000004575 222.0
HKD1_k127_1910163_2 Putative DNA-binding domain - - - 0.00000000000000000000000002199 122.0
HKD1_k127_1910163_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000001815 100.0
HKD1_k127_1910163_4 - - - - 0.000005992 53.0
HKD1_k127_1910163_5 - - - - 0.00001119 52.0
HKD1_k127_1922873_0 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 1.368e-246 773.0
HKD1_k127_1922873_1 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 332.0
HKD1_k127_1946129_0 chloride channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 413.0
HKD1_k127_1946129_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001097 291.0
HKD1_k127_196915_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 355.0
HKD1_k127_196915_1 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004753 263.0
HKD1_k127_196915_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000001932 238.0
HKD1_k127_196915_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000267 165.0
HKD1_k127_196915_4 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000004237 140.0
HKD1_k127_196915_5 phosphorelay signal transduction system - - - 0.0000000000000002667 93.0
HKD1_k127_196915_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000007462 70.0
HKD1_k127_196915_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000002524 76.0
HKD1_k127_196915_8 - K05826 - - 0.00008775 46.0
HKD1_k127_196915_9 Belongs to the peptidase S8 family K13276,K17734 - - 0.0001151 52.0
HKD1_k127_1970435_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 6.543e-233 741.0
HKD1_k127_1970435_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 338.0
HKD1_k127_1970435_2 COG1226 Kef-type K transport systems - - - 0.000001125 61.0
HKD1_k127_1976504_0 creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 352.0
HKD1_k127_1976504_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.000000000000000000000000000000000000000000000000000000000001352 231.0
HKD1_k127_1976504_2 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000004547 215.0
HKD1_k127_1976504_3 glycine decarboxylation via glycine cleavage system K02437 - - 0.000000000000000000000000000000000000000000000000001225 198.0
HKD1_k127_1976504_4 Acyltransferase - - - 0.000000000000000000000000000000000000000000000001038 186.0
HKD1_k127_1976504_5 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000009406 132.0
HKD1_k127_1976504_6 helix_turn_helix gluconate operon transcriptional repressor K07978 - - 0.00000000000000000000003343 117.0
HKD1_k127_1976504_8 - - - - 0.0005129 54.0
HKD1_k127_199499_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 336.0
HKD1_k127_1998564_0 carboxylic acid catabolic process K18334 - 4.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 392.0
HKD1_k127_1998564_1 NIPSNAP family containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000556 224.0
HKD1_k127_1998564_2 and related - - - 0.00000000000000000000000000000000000007207 158.0
HKD1_k127_1998564_3 negative regulation of transcription, DNA-templated K10947 - - 0.000000000000000000000000000000000003091 141.0
HKD1_k127_1998564_4 DoxX K16937 - 1.8.5.2 0.0000000000000000000000000001493 121.0
HKD1_k127_1998564_5 membrane - - - 0.0000000000000000002351 98.0
HKD1_k127_2021347_0 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 568.0
HKD1_k127_2021347_1 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 505.0
HKD1_k127_2021347_10 Binding-protein-dependent transport system inner membrane component K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006284 282.0
HKD1_k127_2021347_12 - - - - 0.000000000000000000000000000000000000000000000000000000007223 212.0
HKD1_k127_2021347_13 Domain of unknown function (DUF5009) - - - 0.00000000000000000000000000000000000000000001872 179.0
HKD1_k127_2021347_14 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000001811 118.0
HKD1_k127_2021347_15 amine dehydrogenase activity K21449 - - 0.0000000000000000000002358 103.0
HKD1_k127_2021347_16 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000001474 97.0
HKD1_k127_2021347_17 Protein of unknown function (DUF1698) - - - 0.00000001273 64.0
HKD1_k127_2021347_18 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000007497 58.0
HKD1_k127_2021347_2 Spermidine putrescine-binding periplasmic protein K11069,K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 466.0
HKD1_k127_2021347_3 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 435.0
HKD1_k127_2021347_4 Aldo/keto reductase family K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 411.0
HKD1_k127_2021347_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 386.0
HKD1_k127_2021347_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 400.0
HKD1_k127_2021347_7 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 329.0
HKD1_k127_2021347_8 - K06862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 306.0
HKD1_k127_2021347_9 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 299.0
HKD1_k127_2025222_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 632.0
HKD1_k127_2025222_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 359.0
HKD1_k127_2025222_10 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000001197 109.0
HKD1_k127_2025222_12 Glycosyl transferase family 41 - - - 0.0000007004 55.0
HKD1_k127_2025222_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000259 274.0
HKD1_k127_2025222_3 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000001784 233.0
HKD1_k127_2025222_4 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000006236 231.0
HKD1_k127_2025222_5 Cytidylyltransferase-like K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000127 162.0
HKD1_k127_2025222_6 PFAM Phosphoribosyltransferase K02242 - - 0.00000000000000000000000000000006924 133.0
HKD1_k127_2025222_7 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000005554 122.0
HKD1_k127_2025222_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000001048 121.0
HKD1_k127_2025222_9 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000009139 119.0
HKD1_k127_2031108_0 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 539.0
HKD1_k127_2031108_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 507.0
HKD1_k127_2031108_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 414.0
HKD1_k127_2031108_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 335.0
HKD1_k127_2031108_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001824 295.0
HKD1_k127_2031108_5 FHA domain - - - 0.00000000000000000000000000000000000000000002677 175.0
HKD1_k127_2031108_6 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000001262 147.0
HKD1_k127_2031108_7 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 0.00000000000000000000002341 116.0
HKD1_k127_2031108_8 PFAM nucleic acid binding, OB-fold, tRNA - - - 0.00000000000000005524 90.0
HKD1_k127_2031108_9 - - - - 0.0000002997 55.0
HKD1_k127_2033423_0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) K01787,K16213 - 5.1.3.11,5.1.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004006 290.0
HKD1_k127_2033423_1 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000001401 253.0
HKD1_k127_2033423_2 ASPIC and UnbV - - - 0.000000000000000000000000000000000006685 143.0
HKD1_k127_2033423_3 - - - - 0.0000000000000000000000001085 110.0
HKD1_k127_2036755_0 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 564.0
HKD1_k127_2036755_1 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000104 190.0
HKD1_k127_2036755_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000003509 139.0
HKD1_k127_2036755_3 - - - - 0.00000001796 66.0
HKD1_k127_2041832_0 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000002979 142.0
HKD1_k127_2041832_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000007112 97.0
HKD1_k127_2041832_2 DUF218 domain - - - 0.000000000000000007753 94.0
HKD1_k127_2063296_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 529.0
HKD1_k127_2063296_1 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000002284 162.0
HKD1_k127_2063296_2 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000008939 122.0
HKD1_k127_2063296_3 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000001414 79.0
HKD1_k127_2065153_0 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000001347 267.0
HKD1_k127_2065153_1 NUDIX domain - - - 0.00000000000000000000000000000000000000000000133 171.0
HKD1_k127_2065153_2 COG NOG04879 non supervised orthologous group K05340 - - 0.000000005406 57.0
HKD1_k127_2078790_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 8.95e-196 621.0
HKD1_k127_2078790_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 473.0
HKD1_k127_2078790_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 466.0
HKD1_k127_2078790_3 Sulfate permease family K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 337.0
HKD1_k127_2081001_0 COGs COG0515 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000002766 248.0
HKD1_k127_2081001_1 beta-galactosidase activity K01195 - 3.2.1.31 0.000000000000000000000000000000000000000000000259 182.0
HKD1_k127_2094696_0 isomerase K01820 - 5.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 587.0
HKD1_k127_2094696_1 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 309.0
HKD1_k127_2094696_2 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005235 256.0
HKD1_k127_2094696_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000007008 262.0
HKD1_k127_2094696_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000003697 237.0
HKD1_k127_2094696_5 Thioredoxin-like - - - 0.000000000000000000000000000000001567 134.0
HKD1_k127_2094696_6 YceI-like domain - - - 0.00000000000001455 82.0
HKD1_k127_2094696_7 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate K00848 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008993,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575 2.7.1.5 0.00000000001306 68.0
HKD1_k127_2094696_8 ATP-independent chaperone mediated protein folding K06006 - - 0.00002086 53.0
HKD1_k127_2121468_0 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 554.0
HKD1_k127_2121468_1 Pilus assembly protein K02662 - - 0.0000000000000000000000295 116.0
HKD1_k127_2122276_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 329.0
HKD1_k127_2122276_1 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001122 264.0
HKD1_k127_2122276_10 Protein of unknown function (DUF3467) - - - 0.000121 53.0
HKD1_k127_2122276_11 - - - - 0.0002329 50.0
HKD1_k127_2122276_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000002224 258.0
HKD1_k127_2122276_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000001452 242.0
HKD1_k127_2122276_4 impB/mucB/samB family K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000704 173.0
HKD1_k127_2122276_5 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000004016 142.0
HKD1_k127_2122276_6 - - - - 0.000000000000000000000000000511 132.0
HKD1_k127_2122276_7 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000009397 86.0
HKD1_k127_2122276_8 Domain of unknown function (DUF4912) K09942 - - 0.0000000000000565 83.0
HKD1_k127_2122276_9 lyase activity - - - 0.000000000008605 76.0
HKD1_k127_2123646_0 PFAM Glycoside hydrolase, family 2, TIM barrel K01190 - 3.2.1.23 0.0 1137.0
HKD1_k127_2123646_1 Voltage gated chloride channel - - - 1.45e-256 803.0
HKD1_k127_2123646_10 PFAM Polysaccharide export protein K01991 - - 0.0000000000000000000000000000000000001865 162.0
HKD1_k127_2123646_11 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000005079 144.0
HKD1_k127_2123646_12 polysaccharide biosynthetic process K19431 - - 0.00000000000000000000000000000007185 143.0
HKD1_k127_2123646_13 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000102 126.0
HKD1_k127_2123646_14 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000009743 111.0
HKD1_k127_2123646_15 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000004102 124.0
HKD1_k127_2123646_16 Glycosyl transferases group 1 - - - 0.0000000000000000000001263 115.0
HKD1_k127_2123646_17 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000001362 107.0
HKD1_k127_2123646_18 lipid-A-disaccharide synthase activity K00748 - 2.4.1.182 0.0000000000000001099 94.0
HKD1_k127_2123646_19 PKD domain containing protein - - - 0.0000000001527 75.0
HKD1_k127_2123646_2 SAF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 563.0
HKD1_k127_2123646_20 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000005241 63.0
HKD1_k127_2123646_3 DegT/DnrJ/EryC1/StrS aminotransferase family K13010,K19430 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 519.0
HKD1_k127_2123646_4 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 476.0
HKD1_k127_2123646_5 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 412.0
HKD1_k127_2123646_6 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 379.0
HKD1_k127_2123646_7 Cytidylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 317.0
HKD1_k127_2123646_8 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001626 276.0
HKD1_k127_2123646_9 NUDIX domain K03207 - - 0.0000000000000000000000000000000000000000000000000000000001311 212.0
HKD1_k127_213910_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 340.0
HKD1_k127_213910_1 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004445 283.0
HKD1_k127_213910_2 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000006008 138.0
HKD1_k127_2153584_0 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 564.0
HKD1_k127_2153584_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 512.0
HKD1_k127_2153584_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 466.0
HKD1_k127_2153584_3 Zinc-binding dehydrogenase K12957 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 358.0
HKD1_k127_2153584_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001958 279.0
HKD1_k127_2153584_5 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000000000002651 103.0
HKD1_k127_2159736_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000002984 232.0
HKD1_k127_2159736_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000006541 221.0
HKD1_k127_2159736_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000006883 144.0
HKD1_k127_2170323_0 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000001993 168.0
HKD1_k127_2170323_1 transcriptional K02483,K07667 GO:0008150,GO:0040007 - 0.0000000002814 72.0
HKD1_k127_2170323_2 Protein of unknown function (DUF721) - - - 0.0003214 53.0
HKD1_k127_2212488_0 PFAM oxidoreductase domain protein - - - 3.122e-217 682.0
HKD1_k127_2212488_1 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 9.14e-204 649.0
HKD1_k127_2212488_2 Glycosyl hydrolases family 8 K15531 - 3.2.1.156 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 496.0
HKD1_k127_2212488_3 PFAM MscS Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 424.0
HKD1_k127_2215359_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 501.0
HKD1_k127_2215359_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 392.0
HKD1_k127_2215359_2 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001999 269.0
HKD1_k127_2215359_3 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000008147 207.0
HKD1_k127_2215359_4 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000003035 191.0
HKD1_k127_2215359_5 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000101 158.0
HKD1_k127_2215359_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000106 134.0
HKD1_k127_2219384_0 Adenosine/AMP deaminase N-terminal K19572 GO:0003674,GO:0003824,GO:0004000,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000002244 214.0
HKD1_k127_2219384_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000002832 132.0
HKD1_k127_2254730_0 Domain of unknown function (DUF4976) - - - 1.05e-248 778.0
HKD1_k127_2254730_1 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000002504 203.0
HKD1_k127_2254730_2 - - - - 0.000000000000000000000000000000000003466 142.0
HKD1_k127_2254730_3 glycosyl transferase family 2 K20444 - - 0.000000001967 70.0
HKD1_k127_2254730_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00002366 51.0
HKD1_k127_227890_0 PFAM Type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 616.0
HKD1_k127_227890_1 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 456.0
HKD1_k127_227890_2 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000718 409.0
HKD1_k127_227890_3 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000008642 192.0
HKD1_k127_227890_4 Phospholipid methyltransferase - - - 0.00000000000000000000000000000007968 130.0
HKD1_k127_227890_5 COG0513 Superfamily II DNA and RNA helicases K17675 - 3.6.4.13 0.0000000001384 66.0
HKD1_k127_227890_6 - - - - 0.0000005672 63.0
HKD1_k127_2316291_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 483.0
HKD1_k127_2316291_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 396.0
HKD1_k127_2316291_2 integrase domain protein SAM domain protein K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 299.0
HKD1_k127_2367198_0 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 347.0
HKD1_k127_2367198_1 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000007921 233.0
HKD1_k127_2367198_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000001622 93.0
HKD1_k127_2367198_3 PASTA K08884,K12132 - 2.7.11.1 0.0000000000000009818 83.0
HKD1_k127_2395878_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 311.0
HKD1_k127_2395878_1 Male sterility protein - - - 0.00000000000001249 87.0
HKD1_k127_2406343_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 368.0
HKD1_k127_2406343_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007766 333.0
HKD1_k127_2406343_2 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000728 254.0
HKD1_k127_2410980_0 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000001826 242.0
HKD1_k127_2410980_1 PFAM regulatory protein, MerR K22491 - - 0.00000000000000000000000000000000000004884 158.0
HKD1_k127_2410980_2 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000000000000106 142.0
HKD1_k127_2410980_3 Uncharacterized conserved protein (DUF2249) - - - 0.00000000001078 75.0
HKD1_k127_2410980_4 Cupin 2, conserved barrel domain protein - - - 0.000002371 57.0
HKD1_k127_2431352_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 3.024e-256 827.0
HKD1_k127_2431352_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 411.0
HKD1_k127_2431352_2 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 374.0
HKD1_k127_2431352_3 Gaf domain K21009 - - 0.00000000000000000000000000000000000000000000000000000000005961 226.0
HKD1_k127_2431352_4 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000001059 175.0
HKD1_k127_2431352_5 COG0457 FOG TPR repeat - - - 0.00000000000009899 80.0
HKD1_k127_2462174_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 9.708e-227 733.0
HKD1_k127_2462174_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 2.649e-201 640.0
HKD1_k127_2462174_10 Major facilitator superfamily K08161 - - 0.0000000000000000000000000000000000000000006874 176.0
HKD1_k127_2462174_11 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000001985 119.0
HKD1_k127_2462174_12 cytochrome - - - 0.0000000000000000000003591 102.0
HKD1_k127_2462174_13 - - - - 0.00000000000000000004766 93.0
HKD1_k127_2462174_14 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000135 79.0
HKD1_k127_2462174_15 iron ion binding - - - 0.000000000003013 76.0
HKD1_k127_2462174_16 Carbon-nitrogen hydrolase - - - 0.000000001638 65.0
HKD1_k127_2462174_2 L-asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 608.0
HKD1_k127_2462174_3 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 455.0
HKD1_k127_2462174_4 GatB/GatE catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 471.0
HKD1_k127_2462174_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 384.0
HKD1_k127_2462174_6 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 356.0
HKD1_k127_2462174_7 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000005857 241.0
HKD1_k127_2462174_8 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000001943 247.0
HKD1_k127_2462174_9 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000005914 218.0
HKD1_k127_247055_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 581.0
HKD1_k127_247055_1 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 400.0
HKD1_k127_247055_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K19517 - 2.7.1.15,2.7.1.64 0.000000000000000000000000000000000000002545 169.0
HKD1_k127_247055_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000007608 138.0
HKD1_k127_2474359_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 5.053e-200 634.0
HKD1_k127_2474359_1 PFAM peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 562.0
HKD1_k127_2474359_2 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 353.0
HKD1_k127_2474359_3 Tetratricopeptide repeat - - - 0.00000000000000000000000798 115.0
HKD1_k127_2474359_4 Ribonuclease H K03469 - 3.1.26.4 0.0000000009356 60.0
HKD1_k127_2474359_5 Heat shock protein DnaJ domain protein K05516 - - 0.00000001577 66.0
HKD1_k127_2516368_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000001003 207.0
HKD1_k127_2516368_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000002354 207.0
HKD1_k127_2516368_2 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000001022 181.0
HKD1_k127_2516368_3 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000001228 176.0
HKD1_k127_2516368_4 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.00000000000000000000000000000000000004088 158.0
HKD1_k127_2516368_5 histone H2A K63-linked ubiquitination K10914 - - 0.0000000000000000000000000000000001782 145.0
HKD1_k127_2516368_6 - - - - 0.0000000000000000000000006087 120.0
HKD1_k127_2516368_7 - - - - 0.0000005674 56.0
HKD1_k127_2516368_8 Hfq protein - - - 0.00001045 51.0
HKD1_k127_2555965_0 beta-galactosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 440.0
HKD1_k127_2555965_1 GAF domain - - - 0.000000000000005717 88.0
HKD1_k127_2555965_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00001948 55.0
HKD1_k127_2563283_0 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 298.0
HKD1_k127_2563283_1 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001957 274.0
HKD1_k127_2563283_2 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000003016 205.0
HKD1_k127_2563283_3 CAAX protease self-immunity K07052 - - 0.0000000001377 74.0
HKD1_k127_2568206_0 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 432.0
HKD1_k127_2568206_1 Memo-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001999 276.0
HKD1_k127_2568206_2 Domain of unknown function (DUF362) - - - 0.000000000002373 80.0
HKD1_k127_2571595_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 376.0
HKD1_k127_2571595_1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 336.0
HKD1_k127_2571595_10 Ribosomal L32p protein family K02911 - - 0.0000000000000000000006976 96.0
HKD1_k127_2571595_11 phosphorelay signal transduction system - - - 0.0000000000000000001197 101.0
HKD1_k127_2571595_12 TonB C terminal - - - 0.0000001787 63.0
HKD1_k127_2571595_13 Outer membrane protein (OmpH-like) K06142 - - 0.0000707 51.0
HKD1_k127_2571595_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001216 274.0
HKD1_k127_2571595_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000002178 264.0
HKD1_k127_2571595_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000005518 252.0
HKD1_k127_2571595_5 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000003741 251.0
HKD1_k127_2571595_6 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000005042 249.0
HKD1_k127_2571595_7 YXWGXW repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000000005346 184.0
HKD1_k127_2571595_8 Alg9-like mannosyltransferase family K05286 - - 0.0000000000000000000000000000000000000000000000000759 197.0
HKD1_k127_2571595_9 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000002861 116.0
HKD1_k127_2574431_0 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 527.0
HKD1_k127_2574431_1 PFAM DinB family - - - 0.00000000000000000000000000000000000000000000000001788 184.0
HKD1_k127_2574431_2 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000004592 155.0
HKD1_k127_2574431_3 Helix-turn-helix domain - - - 0.000001691 53.0
HKD1_k127_2574431_4 - - - - 0.00002668 51.0
HKD1_k127_258401_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.674e-197 621.0
HKD1_k127_258401_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 624.0
HKD1_k127_258401_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000241 282.0
HKD1_k127_258401_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000001085 233.0
HKD1_k127_258401_4 PFAM YbbR family protein - - - 0.000000000000000000000000000000000009075 155.0
HKD1_k127_2585384_0 Belongs to the glycosyl hydrolase 2 family K15855 - 3.2.1.165 0.0 1018.0
HKD1_k127_2585384_1 Glycosyl hydrolase family 30 beta sandwich domain K01201 - 3.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008933 546.0
HKD1_k127_2585384_2 L-lactate permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 539.0
HKD1_k127_2585384_3 Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man) K16213 - 5.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008902 394.0
HKD1_k127_2585384_4 COG3119 Arylsulfatase A K01138 - - 0.000000000000000000000000000000000000000000000000006258 192.0
HKD1_k127_2585384_5 cheY-homologous receiver domain - - - 0.00000000000000000000000004929 119.0
HKD1_k127_2585384_6 ribonuclease BN K07058 - - 0.0000000000000000009383 96.0
HKD1_k127_259034_0 Zinc metalloprotease (Elastase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 453.0
HKD1_k127_259034_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 409.0
HKD1_k127_259034_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 411.0
HKD1_k127_259034_3 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 407.0
HKD1_k127_259034_4 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001022 279.0
HKD1_k127_259034_5 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000005501 172.0
HKD1_k127_259034_6 - - - - 0.00000000003191 75.0
HKD1_k127_2611547_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 451.0
HKD1_k127_2611547_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 374.0
HKD1_k127_2611547_10 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000001313 141.0
HKD1_k127_2611547_11 Membrane - - - 0.0000000000000000000000000000006841 141.0
HKD1_k127_2611547_12 Domain of unknown function (DUF4340) - - - 0.000000000001057 81.0
HKD1_k127_2611547_13 Domain of unknown function (DUF4388) - - - 0.000000001127 71.0
HKD1_k127_2611547_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 370.0
HKD1_k127_2611547_3 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 328.0
HKD1_k127_2611547_4 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003073 273.0
HKD1_k127_2611547_5 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000003291 229.0
HKD1_k127_2611547_6 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000000000000000000000000000000000000000000000000253 216.0
HKD1_k127_2611547_7 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.00000000000000000000000000000000000000000000000000000006969 212.0
HKD1_k127_2611547_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000003936 199.0
HKD1_k127_2611547_9 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000006719 145.0
HKD1_k127_2629862_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 498.0
HKD1_k127_2629862_1 Forkhead associated domain - - - 0.00000000000002438 74.0
HKD1_k127_2629862_2 Hexapeptide repeat of succinyl-transferase - - - 0.000000000006282 67.0
HKD1_k127_2631710_0 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 375.0
HKD1_k127_2631710_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000002939 230.0
HKD1_k127_2631710_2 - - - - 0.00000000000000000000000000000000000000000000004984 188.0
HKD1_k127_2638172_0 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000004725 257.0
HKD1_k127_2638172_1 PFAM Patatin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001579 254.0
HKD1_k127_2638172_2 PFAM PHA accumulation regulator DNA-binding protein - - - 0.00000000000000002823 90.0
HKD1_k127_2638172_3 Phosphate acyltransferases - - - 0.0000000000000004197 79.0
HKD1_k127_2671217_0 Urocanase C-terminal domain K01712 - 4.2.1.49 1.152e-260 824.0
HKD1_k127_2671217_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 523.0
HKD1_k127_2671217_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000009654 232.0
HKD1_k127_2671217_3 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000002076 196.0
HKD1_k127_2671217_4 - - - - 0.000000001106 64.0
HKD1_k127_2692784_0 Fibronectin type III-like domain K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 403.0
HKD1_k127_2692784_1 Thermolysin metallopeptidase, alpha-helical domain K01400,K08777 GO:0005575,GO:0005576 3.4.24.28 0.00000000000000000000000000000000000000000000000000000000000000000000000002601 270.0
HKD1_k127_2701748_0 Ammonium Transporter K03320 - - 2.817e-195 616.0
HKD1_k127_2701748_1 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 466.0
HKD1_k127_2701748_2 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 348.0
HKD1_k127_2701748_3 exonuclease activity K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008325 304.0
HKD1_k127_2701748_4 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000002063 234.0
HKD1_k127_2701748_5 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000002636 196.0
HKD1_k127_2701748_6 - - - - 0.000000000000000000000000002232 124.0
HKD1_k127_2701748_7 Protein of unknown function (DUF4013) - - - 0.000000000000000000006184 102.0
HKD1_k127_2701828_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1227.0
HKD1_k127_2730108_0 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001417 255.0
HKD1_k127_2730108_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000001399 137.0
HKD1_k127_2730108_2 (FHA) domain - - - 0.00000000000000121 79.0
HKD1_k127_2736351_0 DEAD DEAH box K03724 - - 0.0 1340.0
HKD1_k127_2736351_1 metallocarboxypeptidase activity K14054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 494.0
HKD1_k127_2736351_2 Belongs to the thioredoxin family K03671 - - 0.0000000005708 62.0
HKD1_k127_2759154_0 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005501 256.0
HKD1_k127_2759154_1 PFAM PfkB domain protein K00571 - 2.1.1.72 0.00000000000003941 74.0
HKD1_k127_2759154_2 cell redox homeostasis K02199,K03671 - - 0.00000000002456 75.0
HKD1_k127_2766461_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000009886 143.0
HKD1_k127_2766461_1 Gram-negative bacterial TonB protein C-terminal - - - 0.000666 50.0
HKD1_k127_2766930_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 323.0
HKD1_k127_2766930_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000003443 136.0
HKD1_k127_2766930_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000003566 102.0
HKD1_k127_2766930_3 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000001051 70.0
HKD1_k127_2786534_0 ABC transporter C-terminal domain K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 592.0
HKD1_k127_2805156_0 glucose-1-phosphate adenylyltransferase K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000001099 200.0
HKD1_k127_2805156_1 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000004037 137.0
HKD1_k127_2805156_2 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000001014 119.0
HKD1_k127_2805156_3 PDZ DHR GLGF domain protein - - - 0.000000000000000000003177 108.0
HKD1_k127_2805156_4 protein involved in cysteine biosynthesis K06203 - - 0.00000000000000000006823 99.0
HKD1_k127_2814479_0 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 302.0
HKD1_k127_2814479_1 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009389 278.0
HKD1_k127_2814479_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000005249 199.0
HKD1_k127_2814479_3 Transcriptional regulator TetR - - - 0.000000000864 64.0
HKD1_k127_2820992_0 DNA-templated transcription, termination K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 375.0
HKD1_k127_2820992_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 303.0
HKD1_k127_2820992_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000007336 239.0
HKD1_k127_2820992_3 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000002474 220.0
HKD1_k127_2820992_4 Outer membrane efflux protein - - - 0.0001478 54.0
HKD1_k127_2821530_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.134e-215 688.0
HKD1_k127_2821530_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 603.0
HKD1_k127_2821530_2 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 342.0
HKD1_k127_2821530_3 TspO/MBR family K05770 - - 0.000000000000000000000000000000000003306 159.0
HKD1_k127_2821530_4 domain protein K13735,K18491,K20276 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000002121 115.0
HKD1_k127_2830351_0 Cytochrome c554 and c-prime - - - 4.482e-224 719.0
HKD1_k127_2830351_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 570.0
HKD1_k127_2830351_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000858 299.0
HKD1_k127_2830351_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002606 275.0
HKD1_k127_2830351_4 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000000000000000000000000004119 148.0
HKD1_k127_2830351_5 - - - - 0.000000000000000000000000000000007368 143.0
HKD1_k127_2833114_0 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001526 278.0
HKD1_k127_2833114_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000004187 177.0
HKD1_k127_2833114_2 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family K16048 - - 0.000000000000000000000000000000000006857 153.0
HKD1_k127_2833114_3 alpha beta K06889 - - 0.00000000000000000000000000002362 129.0
HKD1_k127_2833114_4 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000001992 77.0
HKD1_k127_2833114_5 - - - - 0.000004223 59.0
HKD1_k127_2838459_0 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000007928 223.0
HKD1_k127_2838459_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000006821 198.0
HKD1_k127_2838459_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000004812 190.0
HKD1_k127_2838459_3 ATP-binding region, ATPase domain protein domain protein K01338,K13587 - 2.7.13.3,3.4.21.53 0.0000000000000000000000000000000005591 148.0
HKD1_k127_2838459_4 ROK family - - - 0.00000001488 56.0
HKD1_k127_2838459_5 HAMP domain - - - 0.000021 55.0
HKD1_k127_2889965_0 ATPase involved in DNA repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 289.0
HKD1_k127_2889965_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007572 268.0
HKD1_k127_2889965_2 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000007034 236.0
HKD1_k127_2889965_3 WHG domain - - - 0.000000000000000000000000000000000000002803 154.0
HKD1_k127_2889965_4 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000009994 144.0
HKD1_k127_2889965_5 - - - - 0.00000000000000005841 93.0
HKD1_k127_2902921_0 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007078 368.0
HKD1_k127_2902921_1 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 331.0
HKD1_k127_2902921_2 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 308.0
HKD1_k127_2902921_3 isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001171 260.0
HKD1_k127_2902921_4 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001924 246.0
HKD1_k127_2902921_5 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000004146 194.0
HKD1_k127_2902921_6 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000001339 173.0
HKD1_k127_2902921_7 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000002266 120.0
HKD1_k127_2902921_8 Belongs to the GcvT family K06980 - - 0.00000000000000000000000466 105.0
HKD1_k127_2955921_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 321.0
HKD1_k127_2955921_1 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000001908 163.0
HKD1_k127_2955921_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000001673 153.0
HKD1_k127_2955921_3 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000002695 144.0
HKD1_k127_2955921_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000001411 58.0
HKD1_k127_2980445_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000004348 252.0
HKD1_k127_2980445_1 Thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000002173 158.0
HKD1_k127_2980445_2 Zn peptidase - - - 0.0000000000000000000000007903 121.0
HKD1_k127_2980445_3 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000001986 83.0
HKD1_k127_2980445_4 Radical SAM domain protein K22227 - - 0.000000000009022 77.0
HKD1_k127_3010057_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1308.0
HKD1_k127_3010057_1 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 327.0
HKD1_k127_3010057_2 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 328.0
HKD1_k127_3010057_3 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008047 287.0
HKD1_k127_3010057_4 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004096 267.0
HKD1_k127_3010057_5 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000002533 219.0
HKD1_k127_3010057_6 phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000002541 207.0
HKD1_k127_3010057_7 DNA-binding transcription factor activity - - - 0.00000000002629 70.0
HKD1_k127_3010057_8 - - - - 0.0000008544 63.0
HKD1_k127_3010057_9 Protein of unknown function (DUF533) - - - 0.0005605 51.0
HKD1_k127_3019920_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000001561 251.0
HKD1_k127_3019920_1 - - - - 0.0006097 53.0
HKD1_k127_3024570_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 481.0
HKD1_k127_3024570_1 Permease YjgP YjgQ family protein K07091,K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 470.0
HKD1_k127_3024570_2 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000104 207.0
HKD1_k127_3024570_3 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000008353 186.0
HKD1_k127_3024570_4 Amidohydrolase family - - - 0.0009642 46.0
HKD1_k127_3029157_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 531.0
HKD1_k127_3029157_1 Belongs to the ClpA ClpB family K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 399.0
HKD1_k127_3029157_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 294.0
HKD1_k127_3029157_3 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001206 311.0
HKD1_k127_3029157_4 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000001015 273.0
HKD1_k127_3029157_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000001615 244.0
HKD1_k127_3029157_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000001796 139.0
HKD1_k127_3029157_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000009363 132.0
HKD1_k127_3029157_8 TM2 domain - - - 0.0000000007057 66.0
HKD1_k127_3029157_9 TolB amino-terminal domain K03641 - - 0.0002485 53.0
HKD1_k127_3049645_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 7.359e-252 790.0
HKD1_k127_3049645_1 Sulfatase K01137 - 3.1.6.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 386.0
HKD1_k127_3049645_2 Arylsulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 295.0
HKD1_k127_3049645_3 lipolytic protein G-D-S-L family K01183 - 3.2.1.14 0.0000000000000000001747 101.0
HKD1_k127_3049645_4 Glycosyl hydrolase family 99 K15538 GO:0000139,GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0004569,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0012505,GO:0015923,GO:0016020,GO:0016787,GO:0016798,GO:0031090,GO:0031984,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0098588,GO:0098791 3.2.1.130 0.00001289 56.0
HKD1_k127_3053896_0 Transcriptional regulator K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 297.0
HKD1_k127_3053896_1 Rnk N-terminus K06140 - - 0.0000000000000000000000000000000003106 140.0
HKD1_k127_3053896_2 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.000000000003866 77.0
HKD1_k127_3056523_0 Glycogen debranching enzyme - - - 0.0 1171.0
HKD1_k127_3056523_1 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 386.0
HKD1_k127_3066921_0 SMART Tetratricopeptide domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 418.0
HKD1_k127_3066921_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000107 288.0
HKD1_k127_3066921_2 transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003663 268.0
HKD1_k127_3066921_3 oxidoreductase activity - - - 0.000000000000000000000003255 119.0
HKD1_k127_3066921_4 Tetratricopeptide repeat - - - 0.00000000001469 74.0
HKD1_k127_3072236_0 aminopeptidase N K01263 - 3.4.11.14 2.458e-231 775.0
HKD1_k127_3072236_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 366.0
HKD1_k127_3072236_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 357.0
HKD1_k127_3072236_3 Natural resistance-associated macrophage protein - - - 0.0000000000582 64.0
HKD1_k127_3072236_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000004622 73.0
HKD1_k127_3073999_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 3.609e-246 793.0
HKD1_k127_3073999_1 PFAM Major Facilitator Superfamily K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 555.0
HKD1_k127_3073999_2 Belongs to the LDH MDH superfamily K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 413.0
HKD1_k127_3073999_3 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 297.0
HKD1_k127_3073999_4 carbohydrate kinase FGGY K00848 - 2.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000001372 241.0
HKD1_k127_3073999_5 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.000000000000000000000000000000000000000000000000000000004351 210.0
HKD1_k127_3073999_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000001635 121.0
HKD1_k127_3080560_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000001599 254.0
HKD1_k127_3080560_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000007016 232.0
HKD1_k127_3080560_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000005061 178.0
HKD1_k127_3080560_3 Could be involved in septation K06412 - - 0.0000000000000000000000000001726 117.0
HKD1_k127_3086388_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 570.0
HKD1_k127_3086388_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 357.0
HKD1_k127_3086388_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002077 278.0
HKD1_k127_3086388_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000006048 286.0
HKD1_k127_3086388_4 Proteasome subunit K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000004284 219.0
HKD1_k127_3086388_5 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000005189 173.0
HKD1_k127_3086388_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000008887 140.0
HKD1_k127_3086388_7 Fibronectin type 3 domain - - - 0.000000000000002435 89.0
HKD1_k127_3086388_8 Regulatory protein, FmdB family - - - 0.000001285 59.0
HKD1_k127_3094871_0 Carboxypeptidase regulatory-like domain - - - 0.0 1186.0
HKD1_k127_3094871_1 Pyrrolo-quinoline quinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 400.0
HKD1_k127_3094871_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 385.0
HKD1_k127_3094871_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342,K03703,K04096 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.00000000000000000000000000000000000000000000000000007638 207.0
HKD1_k127_3094871_4 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000003256 147.0
HKD1_k127_3094871_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000001721 118.0
HKD1_k127_3094871_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.000000000000000000003627 108.0
HKD1_k127_3094871_7 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.00000000000000000002043 106.0
HKD1_k127_3097352_0 malic enzyme K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 1.103e-200 650.0
HKD1_k127_3097352_1 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 584.0
HKD1_k127_3097352_2 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 408.0
HKD1_k127_3097352_3 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 357.0
HKD1_k127_3097352_4 PFAM glycoside hydrolase family 3 K05349 - 3.2.1.21 0.00000000000000000000004527 104.0
HKD1_k127_3103739_0 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 415.0
HKD1_k127_3103739_1 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000273 121.0
HKD1_k127_3103739_2 - - - - 0.000000000000005743 90.0
HKD1_k127_3103739_3 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.000000000007603 71.0
HKD1_k127_3123523_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 317.0
HKD1_k127_3123523_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000414 144.0
HKD1_k127_3123523_2 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000003186 146.0
HKD1_k127_3143701_0 Putative citrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 421.0
HKD1_k127_3143701_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 398.0
HKD1_k127_3143701_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000123 195.0
HKD1_k127_3143701_3 Malate synthase K01638 - 2.3.3.9 0.0004156 47.0
HKD1_k127_3152788_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 379.0
HKD1_k127_3152788_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001468 287.0
HKD1_k127_3152788_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000004037 190.0
HKD1_k127_3152788_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000003012 156.0
HKD1_k127_3152788_4 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000997 147.0
HKD1_k127_3152788_5 Ribosomal protein S18 K02963 - - 0.000000000000000000000000002473 114.0
HKD1_k127_3152788_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000001217 109.0
HKD1_k127_3152788_7 Predicted membrane protein (DUF2232) - - - 0.000000176 63.0
HKD1_k127_3159879_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 490.0
HKD1_k127_3159879_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 310.0
HKD1_k127_3159879_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000018 282.0
HKD1_k127_3159879_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000001092 220.0
HKD1_k127_3159879_4 lipolytic protein G-D-S-L family - - - 0.0000000000003345 79.0
HKD1_k127_3187909_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.0 1448.0
HKD1_k127_3187909_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 7.43e-321 992.0
HKD1_k127_3187909_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 435.0
HKD1_k127_3187909_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003376 274.0
HKD1_k127_3187909_4 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000002382 124.0
HKD1_k127_3187909_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000004836 117.0
HKD1_k127_3187909_6 Glucose / Sorbosone dehydrogenase - - - 0.0000000004622 73.0
HKD1_k127_3213305_0 AMP-binding enzyme C-terminal domain K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 534.0
HKD1_k127_3213305_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 435.0
HKD1_k127_3213305_10 - - - - 0.0000000000000000000000000000000000000282 158.0
HKD1_k127_3213305_11 CoA binding domain K06929 - - 0.00000000000000000000000000000000573 134.0
HKD1_k127_3213305_12 ribosylpyrimidine nucleosidase activity - - - 0.00000000000000000000000001778 112.0
HKD1_k127_3213305_2 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 401.0
HKD1_k127_3213305_3 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 309.0
HKD1_k127_3213305_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 309.0
HKD1_k127_3213305_5 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004734 261.0
HKD1_k127_3213305_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000006699 226.0
HKD1_k127_3213305_7 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.0000000000000000000000000000000000000000000000000004095 194.0
HKD1_k127_3213305_8 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000008361 184.0
HKD1_k127_3213305_9 negative regulation of transcription, DNA-templated - GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000005058 152.0
HKD1_k127_3230235_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 450.0
HKD1_k127_3230235_1 TPR repeat - - - 0.0000000000001097 83.0
HKD1_k127_3237701_0 Pyridine nucleotide-disulphide oxidoreductase K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 299.0
HKD1_k127_3237701_1 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K05299,K05588 - 1.17.1.10,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001253 291.0
HKD1_k127_3237701_2 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000009846 214.0
HKD1_k127_3237701_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000001609 211.0
HKD1_k127_3241164_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 2.435e-286 905.0
HKD1_k127_3241164_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 444.0
HKD1_k127_3241164_10 methyltransferase - - - 0.0000000000000003261 93.0
HKD1_k127_3241164_11 PFAM OmpA MotB domain protein K03640 - - 0.0000000000002777 70.0
HKD1_k127_3241164_12 regulation of translation K05808,K05809 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000008801 60.0
HKD1_k127_3241164_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 327.0
HKD1_k127_3241164_3 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003503 294.0
HKD1_k127_3241164_4 Glucose inhibited division protein A K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000005456 250.0
HKD1_k127_3241164_5 synthase K16167 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006725,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009698,GO:0009699,GO:0009714,GO:0009715,GO:0009987,GO:0016020,GO:0016043,GO:0019438,GO:0019748,GO:0022607,GO:0032991,GO:0034081,GO:0042180,GO:0042181,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000003043 240.0
HKD1_k127_3241164_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000001026 149.0
HKD1_k127_3241164_7 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.000000000000000000000000008184 113.0
HKD1_k127_3241164_8 Outer membrane lipoprotein - - - 0.00000000000000000000002617 111.0
HKD1_k127_3241164_9 PTS HPr component phosphorylation site K11189 - - 0.000000000000000006167 98.0
HKD1_k127_3268574_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 4.135e-288 904.0
HKD1_k127_3268574_1 PFAM Amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 514.0
HKD1_k127_3268574_2 Catalyzes the sodium-dependent transport of glutamate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 377.0
HKD1_k127_3268574_3 Aminotransferase class I and II K00639,K21784 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 313.0
HKD1_k127_3268574_4 PFAM sigma-54 factor interaction domain-containing protein K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 301.0
HKD1_k127_3268574_5 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000003139 199.0
HKD1_k127_3268574_6 Rieske [2Fe-2S] domain - - - 0.0000000000000001521 87.0
HKD1_k127_3268574_7 BON domain - - - 0.0000000000000001776 89.0
HKD1_k127_3268574_8 - - - - 0.000000000000007215 88.0
HKD1_k127_3345866_0 response regulator K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 513.0
HKD1_k127_3345866_1 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 332.0
HKD1_k127_3345866_2 histidine kinase, HAMP K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000224 266.0
HKD1_k127_3345866_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000002506 208.0
HKD1_k127_3345866_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000006948 150.0
HKD1_k127_3345866_5 Phosphatidylglycerophosphatase A K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.00000000000000000000000000002259 134.0
HKD1_k127_3345866_6 LigT like Phosphoesterase K01975 - 3.1.4.58 0.000000000000000000000000003769 124.0
HKD1_k127_3345866_7 RDD family - - - 0.0000004721 62.0
HKD1_k127_3379986_0 Fumarase C C-terminus K01744 - 4.3.1.1 1.61e-208 658.0
HKD1_k127_3379986_1 Inorganic ion transport and metabolism K03319 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 504.0
HKD1_k127_3379986_2 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000000001953 185.0
HKD1_k127_3379986_3 YMGG-like Gly-zipper - - - 0.0000000000006248 72.0
HKD1_k127_3393098_0 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 565.0
HKD1_k127_3393098_1 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 483.0
HKD1_k127_3393098_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000139 223.0
HKD1_k127_3393098_3 Aldo/keto reductase family K00002 - 1.1.1.2 0.00000000000000000000000000000005329 141.0
HKD1_k127_3393098_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000001338 125.0
HKD1_k127_3396986_0 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 390.0
HKD1_k127_3396986_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 296.0
HKD1_k127_3399732_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 436.0
HKD1_k127_3399732_1 Integral membrane protein (intg_mem_TP0381) - - - 0.00000000000000000000000000000000001046 148.0
HKD1_k127_3399732_2 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000002286 127.0
HKD1_k127_3399732_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000002924 69.0
HKD1_k127_3399732_4 - - - - 0.0000000001124 74.0
HKD1_k127_3406200_0 Fibronectin type III-like domain K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 453.0
HKD1_k127_3406200_1 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000002416 119.0
HKD1_k127_3410928_0 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000001205 212.0
HKD1_k127_3410928_1 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000002181 177.0
HKD1_k127_3410928_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000007864 136.0
HKD1_k127_3437209_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1748.0
HKD1_k127_3437209_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 347.0
HKD1_k127_3437209_2 histidine kinase HAMP region domain protein - - - 0.0002138 54.0
HKD1_k127_3438787_0 Sodium:solute symporter family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 346.0
HKD1_k127_3438787_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001088 258.0
HKD1_k127_3488160_0 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 418.0
HKD1_k127_3488160_1 ATP-grasp domain K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000003525 268.0
HKD1_k127_3488160_2 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000169 208.0
HKD1_k127_3488160_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000004814 203.0
HKD1_k127_3503538_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.173e-219 694.0
HKD1_k127_3503538_1 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003638 284.0
HKD1_k127_3503538_2 O-acyltransferase activity K00661 - 2.3.1.79 0.0000000000000000000000000000000000000000000000000000000000000008314 239.0
HKD1_k127_3503538_3 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000006991 228.0
HKD1_k127_3503538_4 Methylmalonyl-CoA mutase K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000001848 183.0
HKD1_k127_3503538_5 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000002715 156.0
HKD1_k127_3503538_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family K03406 - - 0.0000000000000000000000000000000003047 145.0
HKD1_k127_3503538_7 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000003948 138.0
HKD1_k127_3503538_8 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000005759 57.0
HKD1_k127_3507013_0 Ndr family - - - 0.00000000000000000000000000000000000000000000000000000000000006533 222.0
HKD1_k127_3507013_1 ABC-type Mn2 Zn2 transport systems permease components K09816 - - 0.0000000000000000000000000000000000000000000000000001504 202.0
HKD1_k127_3507013_2 COG1121 ABC-type Mn Zn transport systems ATPase component K09817 - - 0.000000000000000000000000000000000000000000000001961 194.0
HKD1_k127_3507013_3 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.0000000000000000000000000000000000000000000000405 190.0
HKD1_k127_3507013_4 Belongs to the bacterial solute-binding protein 9 family K09818 - - 0.000000000000000000000000000000000000111 155.0
HKD1_k127_3507013_5 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.000000000000000000000000002513 116.0
HKD1_k127_3517575_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 400.0
HKD1_k127_3517575_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 308.0
HKD1_k127_3517575_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001493 291.0
HKD1_k127_3517575_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000272 247.0
HKD1_k127_3517575_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000003378 201.0
HKD1_k127_3517575_5 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000003708 215.0
HKD1_k127_3517575_6 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000001025 177.0
HKD1_k127_3517597_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 340.0
HKD1_k127_3517597_1 EamA-like transporter family - - - 0.0000000001683 68.0
HKD1_k127_3517597_2 AsmA-like C-terminal region K07289 - - 0.00001677 57.0
HKD1_k127_3517838_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 383.0
HKD1_k127_3517838_1 stem vascular tissue pattern formation - - - 0.000000000000000000000000007674 117.0
HKD1_k127_3517838_2 MotA/TolQ/ExbB proton channel family K03561 - - 0.00001712 55.0
HKD1_k127_3519396_0 Sodium:solute symporter family - - - 6.529e-286 888.0
HKD1_k127_3519396_1 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 355.0
HKD1_k127_3519396_2 KR domain K13774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 289.0
HKD1_k127_3519396_3 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001602 255.0
HKD1_k127_3519396_4 UPF0056 membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000001696 222.0
HKD1_k127_3519396_5 Cytochrome C' - - - 0.000000000000000000002133 104.0
HKD1_k127_3519396_6 aminotransferase class I and II K00375 - - 0.0000000001067 67.0
HKD1_k127_3521791_0 AcrB/AcrD/AcrF family K15726 - - 9.984e-227 728.0
HKD1_k127_3521791_1 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000004883 209.0
HKD1_k127_3521791_2 DUF218 domain - - - 0.0000000000000000001982 98.0
HKD1_k127_3521791_3 Belongs to the P(II) protein family K04752 - - 0.000000000000000003762 88.0
HKD1_k127_3521791_4 Protein of unknown function (DUF2911) - - - 0.000000000000183 77.0
HKD1_k127_3521791_6 - - - - 0.0000000000007628 77.0
HKD1_k127_3521791_7 Sulfurtransferase - - - 0.000000000206 69.0
HKD1_k127_3547767_1 Glycosyl transferase, family 2 K01002,K20534 - 2.7.8.20 0.0000000000000000000000000000000000000002037 168.0
HKD1_k127_3547767_2 Glycosyl transferase family 2 - - - 0.000000000004424 79.0
HKD1_k127_3554154_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 446.0
HKD1_k127_3554154_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000003601 200.0
HKD1_k127_3554154_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000003856 103.0
HKD1_k127_3564731_0 Peptidase family M28 - - - 1.815e-299 965.0
HKD1_k127_3564731_1 Glycoside hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 446.0
HKD1_k127_3564731_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000001036 212.0
HKD1_k127_3569312_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5.393e-313 984.0
HKD1_k127_3569312_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 531.0
HKD1_k127_3569312_2 GDP-mannose 4,6 dehydratase K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 464.0
HKD1_k127_3569312_3 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 389.0
HKD1_k127_3569312_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 375.0
HKD1_k127_3569312_5 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 340.0
HKD1_k127_3569312_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 304.0
HKD1_k127_3569312_7 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 317.0
HKD1_k127_3569312_8 - - - - 0.000000000000000007053 95.0
HKD1_k127_3569312_9 PBS lyase HEAT-like repeat - - - 0.0000000003076 73.0
HKD1_k127_3584509_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 538.0
HKD1_k127_3584509_1 phenylalanyl-tRNA synthetase (beta subunit) K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 461.0
HKD1_k127_3584509_10 TIGRFAM MJ0042 family finger-like protein - - - 0.000000000000001164 90.0
HKD1_k127_3584509_11 Cell division protein ZapA K09888 - - 0.000000000001271 72.0
HKD1_k127_3584509_12 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000004435 67.0
HKD1_k127_3584509_13 Protein of unknown function (DUF2752) - - - 0.00000000979 69.0
HKD1_k127_3584509_14 Glycosyl transferase 4-like domain - - - 0.00000001502 68.0
HKD1_k127_3584509_2 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 385.0
HKD1_k127_3584509_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 357.0
HKD1_k127_3584509_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000001653 223.0
HKD1_k127_3584509_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000002349 200.0
HKD1_k127_3584509_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000003086 136.0
HKD1_k127_3584509_7 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000001104 106.0
HKD1_k127_3584509_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000007561 89.0
HKD1_k127_3584509_9 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000009615 83.0
HKD1_k127_3588562_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 1.876e-277 870.0
HKD1_k127_3588562_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 5.306e-246 775.0
HKD1_k127_3588562_10 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000002907 112.0
HKD1_k127_3588562_2 PFAM peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 539.0
HKD1_k127_3588562_3 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 472.0
HKD1_k127_3588562_4 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 337.0
HKD1_k127_3588562_5 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 336.0
HKD1_k127_3588562_6 Flavin-nucleotide-binding protein K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002541 261.0
HKD1_k127_3588562_7 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000003474 194.0
HKD1_k127_3588562_8 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000000001318 141.0
HKD1_k127_3588562_9 Thioesterase superfamily K10806 - - 0.000000000000000000000000004256 118.0
HKD1_k127_3609223_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 326.0
HKD1_k127_3609223_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 328.0
HKD1_k127_3609223_2 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 331.0
HKD1_k127_3609223_3 ribonuclease inhibitor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000115 273.0
HKD1_k127_3609223_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000006302 227.0
HKD1_k127_3609223_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000004171 185.0
HKD1_k127_3609223_6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000239 174.0
HKD1_k127_3609223_7 4Fe-4S dicluster domain K05524 - - 0.000000000000000000000000000000000001295 140.0
HKD1_k127_3616615_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 1.269e-225 715.0
HKD1_k127_3617730_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 440.0
HKD1_k127_3617730_1 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 411.0
HKD1_k127_3617730_2 PFAM virulence factor family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 411.0
HKD1_k127_3617730_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000001005 207.0
HKD1_k127_3617730_4 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.0000000000000000000000000000000000000000009047 168.0
HKD1_k127_3617730_5 PFAM OsmC family protein - - - 0.00000000000000000000000000000000000000003119 155.0
HKD1_k127_3617730_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000003025 156.0
HKD1_k127_3617730_7 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000004998 149.0
HKD1_k127_3617730_8 Serine aminopeptidase, S33 K06889 - - 0.0007086 50.0
HKD1_k127_3650460_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 507.0
HKD1_k127_3650460_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 371.0
HKD1_k127_3650460_2 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000006014 220.0
HKD1_k127_3650460_3 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000004306 143.0
HKD1_k127_3650460_4 - - - - 0.00000000000000000000000000000000004525 155.0
HKD1_k127_3654533_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000178 289.0
HKD1_k127_3654533_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000001001 224.0
HKD1_k127_3654533_2 - K07112 - - 0.0000000000000000000000000000000000000000000000000000002608 201.0
HKD1_k127_3654533_3 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.00000000000000000013 88.0
HKD1_k127_3660978_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 7.692e-207 655.0
HKD1_k127_3660978_1 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 603.0
HKD1_k127_3660978_2 histidine kinase A domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 494.0
HKD1_k127_3660978_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000004325 183.0
HKD1_k127_3660978_4 DinB family - - - 0.0000000000000000000000000000000000000000000002039 173.0
HKD1_k127_3660978_5 Penicillin binding protein transpeptidase domain K02172 - - 0.0000000000000000000000000000000000000000000004957 190.0
HKD1_k127_3660978_6 - - - - 0.0000000000000000000003006 113.0
HKD1_k127_3660978_7 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000002041 51.0
HKD1_k127_3661011_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 447.0
HKD1_k127_3661011_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 421.0
HKD1_k127_3661011_10 O-methyltransferase activity - - - 0.0002336 46.0
HKD1_k127_3661011_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 353.0
HKD1_k127_3661011_3 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 299.0
HKD1_k127_3661011_4 LysM domain protein K07261 - - 0.000000000000000000000000000000000000000000000000000000000000000004434 241.0
HKD1_k127_3661011_5 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000001077 223.0
HKD1_k127_3661011_6 3-methyladenine DNA glycosylase - - - 0.00000000000000000000000000000000000000000000000000000000001326 227.0
HKD1_k127_3661011_7 Esterase-like activity of phytase - - - 0.0000000000000000000000000000000000000000000001803 183.0
HKD1_k127_3661011_8 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000422 136.0
HKD1_k127_3661011_9 Sigma-54 interaction domain K10126 - - 0.000006504 51.0
HKD1_k127_3665041_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1165.0
HKD1_k127_3665041_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639,K21784 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002224 286.0
HKD1_k127_3665041_2 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.0000000000000000000000000000000000000000000001364 183.0
HKD1_k127_3665041_3 GtrA-like protein K00995 - 2.7.8.5 0.000000000000000000000000004129 128.0
HKD1_k127_3665041_4 acetyltransferase - - - 0.0000000000005349 82.0
HKD1_k127_3665041_5 Acetoacetate decarboxylase (ADC) - - - 0.000541 51.0
HKD1_k127_3665041_6 Pfam:DUF385 - - - 0.0009234 48.0
HKD1_k127_3677375_0 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 1.618e-295 927.0
HKD1_k127_3677375_1 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000006154 263.0
HKD1_k127_3677375_2 Exonuclease K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000002287 256.0
HKD1_k127_3677375_3 Glycosyl transferase family 2 K09931 - - 0.000000000000000000000000000000000001254 149.0
HKD1_k127_3677375_4 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000000000000000000003258 125.0
HKD1_k127_3677375_5 Inosine-uridine preferring nucleoside hydrolase - - - 0.00000000000000000000003155 106.0
HKD1_k127_3677375_6 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000001088 98.0
HKD1_k127_3677375_7 Histidine kinase - - - 0.0000000000000003082 83.0
HKD1_k127_3720396_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1142.0
HKD1_k127_3720396_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 574.0
HKD1_k127_3720396_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000008504 139.0
HKD1_k127_3720396_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K07025 - - 0.0000000000000000000000001375 112.0
HKD1_k127_3720396_2 Glycosyl hydrolase family 115 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 567.0
HKD1_k127_3720396_3 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 395.0
HKD1_k127_3720396_4 Pfam Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 351.0
HKD1_k127_3720396_5 Transcriptional regulator K02529,K07506 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 357.0
HKD1_k127_3720396_6 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004294 266.0
HKD1_k127_3720396_7 PFAM Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000192 241.0
HKD1_k127_3720396_8 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000229 255.0
HKD1_k127_3720396_9 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000005969 216.0
HKD1_k127_3741034_0 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 7.275e-222 706.0
HKD1_k127_3741034_1 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 364.0
HKD1_k127_3741034_2 Winged helix DNA-binding domain K09927 - - 0.0000000000000000000000000000000000000000000000000000000005324 217.0
HKD1_k127_3741034_3 PFAM adenosine AMP deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000002178 156.0
HKD1_k127_3741034_4 Haloacid dehalogenase-like hydrolase K02566 - - 0.00002351 56.0
HKD1_k127_3746112_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 6.032e-200 632.0
HKD1_k127_3746112_1 Cysteine desulfurase K01766,K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 569.0
HKD1_k127_3746112_2 PFAM Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 456.0
HKD1_k127_3746112_3 FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 376.0
HKD1_k127_3746112_4 FeS assembly protein SufD K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 343.0
HKD1_k127_3746112_5 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000007982 145.0
HKD1_k127_3746112_6 biosynthesis protein K08253 - 2.7.10.2 0.00000000000000000000007049 112.0
HKD1_k127_3746112_7 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000002919 98.0
HKD1_k127_3746112_8 Histidine kinase - - - 0.00000000000004269 85.0
HKD1_k127_3757345_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 426.0
HKD1_k127_3757345_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 392.0
HKD1_k127_3757345_2 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 380.0
HKD1_k127_3757345_3 amine dehydrogenase activity K14647,K21449 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000014 289.0
HKD1_k127_3757345_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000005014 141.0
HKD1_k127_3757345_5 - - - - 0.00000000000000000000000001321 128.0
HKD1_k127_3757345_6 membrane - - - 0.000000000002583 78.0
HKD1_k127_3806009_0 glutamine synthetase K01915 - 6.3.1.2 1.889e-228 717.0
HKD1_k127_3806009_1 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000004089 219.0
HKD1_k127_3806009_2 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.00000000000000000000000000000000000000000000000000004361 213.0
HKD1_k127_3806009_3 Histidine kinase K13598 - 2.7.13.3 0.0000000000000000000000000000000000003466 162.0
HKD1_k127_3806009_4 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000003658 145.0
HKD1_k127_3806009_5 - - - - 0.00000000000000005889 94.0
HKD1_k127_3829942_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 336.0
HKD1_k127_3829942_1 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001141 287.0
HKD1_k127_3829942_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009544 281.0
HKD1_k127_3829942_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000027 194.0
HKD1_k127_3829942_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000004967 141.0
HKD1_k127_3829942_5 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000002448 132.0
HKD1_k127_3829942_6 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000003767 101.0
HKD1_k127_3829942_7 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K02169 - 2.1.1.197,2.1.1.222,2.1.1.64 0.0009392 49.0
HKD1_k127_383953_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 582.0
HKD1_k127_383953_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 485.0
HKD1_k127_383953_11 Protein of unknown function (DUF1211) - - - 0.00000505 58.0
HKD1_k127_383953_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 436.0
HKD1_k127_383953_3 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 439.0
HKD1_k127_383953_4 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 326.0
HKD1_k127_383953_5 PFAM response regulator receiver K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 295.0
HKD1_k127_383953_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 303.0
HKD1_k127_383953_7 Integral membrane sensor signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001349 292.0
HKD1_k127_383953_9 Stringent starvation protein B K09985 - - 0.00000000000000000000000000000000000003774 152.0
HKD1_k127_3849766_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006959 265.0
HKD1_k127_3849766_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000006725 238.0
HKD1_k127_3849766_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000004788 208.0
HKD1_k127_3849766_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000004574 182.0
HKD1_k127_3849766_4 SCO1/SenC K07152,K08976 - - 0.0000000000000000000000000000002479 138.0
HKD1_k127_3849766_5 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000002718 131.0
HKD1_k127_3849766_6 Glycoprotease K14742 - - 0.00000000000000000000000000005202 124.0
HKD1_k127_3849766_7 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000001675 93.0
HKD1_k127_3849766_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000005777 81.0
HKD1_k127_3855083_0 Acetyl propionyl-CoA carboxylase alpha subunit K01968 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 520.0
HKD1_k127_3855083_1 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000005846 243.0
HKD1_k127_3855083_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000231 226.0
HKD1_k127_3855083_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000007525 223.0
HKD1_k127_3855083_4 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000002613 136.0
HKD1_k127_3855083_5 anti-sigma regulatory factor K04757 - 2.7.11.1 0.00000000000000000001036 98.0
HKD1_k127_3855083_6 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000002988 95.0
HKD1_k127_3855083_7 Acetyl propionyl-CoA carboxylase alpha subunit K01968,K13777 - 6.4.1.4,6.4.1.5 0.00000000000006154 82.0
HKD1_k127_3858143_0 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 594.0
HKD1_k127_3858143_1 oligopeptide transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 479.0
HKD1_k127_3858143_10 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000008514 185.0
HKD1_k127_3858143_11 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000001508 197.0
HKD1_k127_3858143_12 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000037 183.0
HKD1_k127_3858143_13 4Fe-4S binding domain - - - 0.000000000000000000000000000001862 122.0
HKD1_k127_3858143_14 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.000000000000000000000002975 112.0
HKD1_k127_3858143_15 SMART Parallel beta-helix repeat - - - 0.0000000144 65.0
HKD1_k127_3858143_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 486.0
HKD1_k127_3858143_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 334.0
HKD1_k127_3858143_4 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003326 287.0
HKD1_k127_3858143_5 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001056 273.0
HKD1_k127_3858143_6 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000000000000000000000002302 208.0
HKD1_k127_3858143_7 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000009851 202.0
HKD1_k127_3858143_8 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000009516 197.0
HKD1_k127_3858143_9 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000001574 201.0
HKD1_k127_3934856_0 4Fe-4S dicluster domain K00184 - - 5.064e-241 763.0
HKD1_k127_3934856_1 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006462 275.0
HKD1_k127_3936297_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.633e-235 755.0
HKD1_k127_3936297_1 Transglycosylase K08309 - - 0.0000000000000000000000000000000000000002785 161.0
HKD1_k127_3936297_2 Mitochondrial biogenesis AIM24 - - - 0.000000000000000001005 100.0
HKD1_k127_3936297_3 Domain of unknown function (DUF4870) - - - 0.0000000002056 72.0
HKD1_k127_3936297_4 Zn peptidase - - - 0.000000003711 68.0
HKD1_k127_3964491_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000001088 147.0
HKD1_k127_3964491_1 WD40 domain protein beta Propeller K03641 - - 0.0000000000000000000000000551 121.0
HKD1_k127_3964491_2 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000122 100.0
HKD1_k127_396599_0 Fibronectin type III-like domain K05349 - 3.2.1.21 7.63e-214 679.0
HKD1_k127_396599_1 Belongs to the type-B carboxylesterase lipase family K01044,K01049,K01050,K01063,K03927,K07378,K14999,K15743 GO:0000003,GO:0000902,GO:0000904,GO:0001941,GO:0003674,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005604,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006897,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0007155,GO:0007158,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007416,GO:0007610,GO:0007617,GO:0007618,GO:0008037,GO:0008038,GO:0008039,GO:0008045,GO:0008150,GO:0009605,GO:0009607,GO:0009653,GO:0009986,GO:0009987,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0016192,GO:0016201,GO:0016787,GO:0016788,GO:0019098,GO:0019953,GO:0022008,GO:0022414,GO:0022607,GO:0022610,GO:0023051,GO:0030030,GO:0030154,GO:0030182,GO:0030431,GO:0031012,GO:0031175,GO:0031224,GO:0031226,GO:0032501,GO:0032502,GO:0032504,GO:0032989,GO:0032990,GO:0036465,GO:0040011,GO:0042043,GO:0042221,GO:0042330,GO:0043207,GO:0044085,GO:0044091,GO:0044421,GO:0044425,GO:0044459,GO:0044464,GO:0044703,GO:0045202,GO:0048468,GO:0048488,GO:0048609,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050794,GO:0050804,GO:0050808,GO:0050896,GO:0050919,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051704,GO:0051707,GO:0052689,GO:0060179,GO:0061024,GO:0061564,GO:0062023,GO:0065007,GO:0071709,GO:0071840,GO:0071944,GO:0097090,GO:0097104,GO:0097105,GO:0097485,GO:0098542,GO:0098609,GO:0098657,GO:0099003,GO:0099054,GO:0099068,GO:0099172,GO:0099173,GO:0099177,GO:0099504,GO:0120036,GO:0120039 3.1.1.1,3.1.1.56,3.1.1.59,3.1.1.7,3.1.1.8,3.1.1.84 0.000000000000009876 88.0
HKD1_k127_3991971_0 AcrB/AcrD/AcrF family - - - 1.53e-303 958.0
HKD1_k127_3991971_1 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000003811 209.0
HKD1_k127_3991971_2 Outer membrane efflux protein - - - 0.0000000000000000008049 100.0
HKD1_k127_401581_0 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 460.0
HKD1_k127_401581_1 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002658 268.0
HKD1_k127_401581_2 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000004462 126.0
HKD1_k127_4030768_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000002108 251.0
HKD1_k127_4030768_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000001174 127.0
HKD1_k127_4030768_2 PFAM Glycoside hydrolase 15-related - - - 0.000000000000000000000002489 117.0
HKD1_k127_4030768_3 peptidase K07386 - - 0.000000000002446 67.0
HKD1_k127_4030768_4 peptidase K07386 - - 0.0000000001129 76.0
HKD1_k127_4030768_5 Methyltransferase type 11 - - - 0.000000007411 69.0
HKD1_k127_4030768_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000005929 62.0
HKD1_k127_4056819_0 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 498.0
HKD1_k127_4056819_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 483.0
HKD1_k127_4056819_2 PFAM Glycosyl Hydrolase Family 88 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 415.0
HKD1_k127_4076547_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 573.0
HKD1_k127_4076547_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 395.0
HKD1_k127_4076547_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000709 248.0
HKD1_k127_4076547_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000002431 93.0
HKD1_k127_4078223_0 Zinc carboxypeptidase - - - 4.106e-220 711.0
HKD1_k127_4078223_1 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 339.0
HKD1_k127_4078223_2 Type II secretory pathway, component ExeA K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 323.0
HKD1_k127_4078223_3 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 332.0
HKD1_k127_4078223_4 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000336 281.0
HKD1_k127_4078223_5 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000004447 170.0
HKD1_k127_4078223_6 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.00000000000000000000000000000000000000006388 159.0
HKD1_k127_4078223_7 nickel cation binding K04651 - - 0.000000000000000000000000001893 114.0
HKD1_k127_4078223_8 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.00000001411 56.0
HKD1_k127_4104996_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 552.0
HKD1_k127_4104996_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 478.0
HKD1_k127_4104996_2 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000007603 193.0
HKD1_k127_4104996_3 Protein of unknown function (DUF2911) - - - 0.0000000000000000001076 98.0
HKD1_k127_4104996_4 - - - - 0.00000000000003419 74.0
HKD1_k127_4119675_0 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 409.0
HKD1_k127_415068_0 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 325.0
HKD1_k127_415068_1 Uncharacterised conserved protein (DUF2156) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 325.0
HKD1_k127_415068_2 Biotin-lipoyl like K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000001746 259.0
HKD1_k127_415068_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.00000000000000000000000000000000000000002878 157.0
HKD1_k127_415068_4 outer membrane efflux protein K15725 - - 0.0000000000000000000000000003272 133.0
HKD1_k127_415068_5 SNARE associated Golgi protein - - - 0.0000000000002374 85.0
HKD1_k127_4151702_0 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 387.0
HKD1_k127_4151702_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 374.0
HKD1_k127_4151702_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001386 270.0
HKD1_k127_4151702_3 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000002721 82.0
HKD1_k127_4154155_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 9.905e-209 666.0
HKD1_k127_4154155_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 380.0
HKD1_k127_4154155_10 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000008103 120.0
HKD1_k127_4154155_11 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000001126 127.0
HKD1_k127_4154155_12 DoxX - - - 0.000000000000000004662 95.0
HKD1_k127_4154155_13 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000001138 90.0
HKD1_k127_4154155_14 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.0000000000000001246 85.0
HKD1_k127_4154155_15 - - - - 0.000000000000000264 85.0
HKD1_k127_4154155_16 3D domain - - - 0.00000000000002722 80.0
HKD1_k127_4154155_17 Involved in the tonB-independent uptake of proteins - - - 0.0000000000008841 79.0
HKD1_k127_4154155_18 Rhodanese Homology Domain - - - 0.00000000000716 72.0
HKD1_k127_4154155_19 peptidyl-tyrosine sulfation - - - 0.0000000001235 75.0
HKD1_k127_4154155_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000003565 273.0
HKD1_k127_4154155_20 YacP-like NYN domain K06962 - - 0.0004662 49.0
HKD1_k127_4154155_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000006368 217.0
HKD1_k127_4154155_4 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000000285 182.0
HKD1_k127_4154155_5 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000009671 168.0
HKD1_k127_4154155_6 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000002293 167.0
HKD1_k127_4154155_7 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000002132 158.0
HKD1_k127_4154155_8 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000006381 163.0
HKD1_k127_4154155_9 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000002293 132.0
HKD1_k127_4169653_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1110.0
HKD1_k127_4169653_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000009042 79.0
HKD1_k127_4207574_0 WD40-like Beta Propeller Repeat - - - 7.779e-206 652.0
HKD1_k127_4207574_1 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000001638 252.0
HKD1_k127_4207574_2 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000006671 142.0
HKD1_k127_4207574_3 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000001715 100.0
HKD1_k127_4207574_4 phosphorelay signal transduction system K19622 - - 0.000000000000000000007791 104.0
HKD1_k127_4212644_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 9.872e-219 690.0
HKD1_k127_4212644_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 454.0
HKD1_k127_4212644_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006151 293.0
HKD1_k127_4212644_3 DinB family - - - 0.000000000000000000000000000000000000000005954 159.0
HKD1_k127_4212644_5 TPR repeat - - - 0.000004138 57.0
HKD1_k127_4216981_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 385.0
HKD1_k127_4216981_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000000004369 203.0
HKD1_k127_4216981_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000186 119.0
HKD1_k127_4216981_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000008817 109.0
HKD1_k127_4216981_4 Domain of unknown function (DUF4388) - - - 0.0005807 52.0
HKD1_k127_4234687_0 CoA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 492.0
HKD1_k127_4234687_1 Polysaccharide biosynthesis protein K15894,K17716 - 4.2.1.115,5.1.3.2 0.0000000000000000000000000000000000000000000000000129 184.0
HKD1_k127_4234687_2 O-Antigen ligase - - - 0.000000000000000000000000000000000000002938 168.0
HKD1_k127_4234687_3 Evidence 4 Homologs of previously reported genes of - - - 0.00002173 48.0
HKD1_k127_4235747_0 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 514.0
HKD1_k127_4235747_1 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 288.0
HKD1_k127_4235747_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000002074 214.0
HKD1_k127_4235747_3 Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000000000000000000000000000001213 200.0
HKD1_k127_4235747_4 - - - - 0.000000000000000000000000000000000009501 142.0
HKD1_k127_4235747_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000001894 119.0
HKD1_k127_4270830_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 3.308e-197 631.0
HKD1_k127_4322030_0 penicillin-binding protein - - - 0.000000000000000000000000000000000000004342 162.0
HKD1_k127_4322030_1 Peptidase M56 K03646 - - 0.000007137 53.0
HKD1_k127_4323362_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K17217 - 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 447.0
HKD1_k127_4323362_1 EVE domain - - - 0.0000000000000000000000000000000000000001005 154.0
HKD1_k127_4323362_2 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000007832 113.0
HKD1_k127_4323362_3 Stage II sporulation D domain protein K06381 - - 0.000000000000000005289 100.0
HKD1_k127_4328420_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 5.054e-232 733.0
HKD1_k127_4328420_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 513.0
HKD1_k127_4328420_10 PFAM Protein kinase domain - - - 0.000003311 58.0
HKD1_k127_4328420_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 466.0
HKD1_k127_4328420_3 Domain of Unknown Function (DUF349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 334.0
HKD1_k127_4328420_4 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 309.0
HKD1_k127_4328420_5 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000001626 243.0
HKD1_k127_4328420_6 - - - - 0.00000000000000000000000000000000002868 150.0
HKD1_k127_4328420_7 Protein-disulfide isomerase - - - 0.000000000000000000000002534 117.0
HKD1_k127_4328420_8 NUDIX domain - - - 0.00000000000000000000009225 105.0
HKD1_k127_4328420_9 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.00000000000003029 82.0
HKD1_k127_4332537_0 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 380.0
HKD1_k127_4332537_1 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000000000000000000000000000007553 224.0
HKD1_k127_4332537_2 - - - - 0.00000001628 68.0
HKD1_k127_4332622_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0 1078.0
HKD1_k127_4332622_1 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 481.0
HKD1_k127_4332622_10 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000001408 233.0
HKD1_k127_4332622_11 cobalamin-transporting ATPase activity K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000002246 234.0
HKD1_k127_4332622_12 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000003686 207.0
HKD1_k127_4332622_13 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000005755 206.0
HKD1_k127_4332622_14 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000848 183.0
HKD1_k127_4332622_15 PFAM ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000001759 199.0
HKD1_k127_4332622_16 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000005726 167.0
HKD1_k127_4332622_17 AntiSigma factor - - - 0.0000000000000000000000002646 118.0
HKD1_k127_4332622_18 Protein of unknown function (DUF1211) - - - 0.00000000000000000000002892 108.0
HKD1_k127_4332622_19 zinc ion binding K06204 - - 0.000000001254 67.0
HKD1_k127_4332622_2 Amino acid kinase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 467.0
HKD1_k127_4332622_20 Protein of unknown function (DUF429) - - - 0.00000003576 65.0
HKD1_k127_4332622_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 444.0
HKD1_k127_4332622_4 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 403.0
HKD1_k127_4332622_5 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 372.0
HKD1_k127_4332622_6 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 354.0
HKD1_k127_4332622_7 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 306.0
HKD1_k127_4332622_8 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000003517 247.0
HKD1_k127_4332622_9 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004526 242.0
HKD1_k127_4347975_0 Dienelactone hydrolase family - - - 0.0 1232.0
HKD1_k127_4347975_1 Belongs to the GARS family K01945,K01952,K13713 - 6.3.2.6,6.3.4.13,6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 434.0
HKD1_k127_4347975_10 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.0000000000000000000000000000000000000000000000000004634 195.0
HKD1_k127_4347975_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 396.0
HKD1_k127_4347975_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 327.0
HKD1_k127_4347975_4 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 296.0
HKD1_k127_4347975_5 ABC-type transport system involved in lysophospholipase L1 biosynthesis ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002359 248.0
HKD1_k127_4347975_6 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000005041 224.0
HKD1_k127_4347975_7 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000009934 225.0
HKD1_k127_4347975_8 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000002253 220.0
HKD1_k127_4347975_9 Serine aminopeptidase, S33 K07019 - - 0.00000000000000000000000000000000000000000000000000000000001334 219.0
HKD1_k127_4348021_0 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 2.987e-276 867.0
HKD1_k127_4348021_1 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 456.0
HKD1_k127_4348021_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 428.0
HKD1_k127_4348021_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 403.0
HKD1_k127_4348021_4 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 327.0
HKD1_k127_4348021_5 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 293.0
HKD1_k127_4348021_6 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008321 291.0
HKD1_k127_4348021_7 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001164 267.0
HKD1_k127_4348021_8 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001749 261.0
HKD1_k127_4348021_9 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000009383 90.0
HKD1_k127_4381276_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000004786 211.0
HKD1_k127_4381276_1 Phage integrase family - - - 0.00000007401 64.0
HKD1_k127_4470773_0 amino acid transport K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 503.0
HKD1_k127_4470773_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 353.0
HKD1_k127_4470773_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 355.0
HKD1_k127_4470773_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.000000000000000000000000000000000000000000000004079 186.0
HKD1_k127_4470773_4 - - - - 0.000000000000000000000000000000000000000002576 165.0
HKD1_k127_4470773_5 - - - - 0.0000000000000000000000000000000000007516 160.0
HKD1_k127_4470773_6 COG2146 Ferredoxin subunits of nitrite reductase and K00363 - 1.7.1.15 0.00000000000000000000003275 102.0
HKD1_k127_4470773_7 Tfp pilus assembly protein FimV - - - 0.0000000000000000000001401 108.0
HKD1_k127_4470773_8 - - - - 0.000004676 56.0
HKD1_k127_4499744_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 572.0
HKD1_k127_4499744_1 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 467.0
HKD1_k127_4503132_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 457.0
HKD1_k127_4503132_1 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 351.0
HKD1_k127_4503132_2 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000001834 207.0
HKD1_k127_4514947_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1034.0
HKD1_k127_4514947_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.422e-240 759.0
HKD1_k127_4514947_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 551.0
HKD1_k127_4514947_3 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007669 286.0
HKD1_k127_4514947_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000006339 244.0
HKD1_k127_4537603_0 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 3.997e-198 623.0
HKD1_k127_4537603_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 567.0
HKD1_k127_4537603_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 437.0
HKD1_k127_4537603_3 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000009435 264.0
HKD1_k127_4537603_5 Leishmanolysin - - - 0.00000002196 64.0
HKD1_k127_4542853_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 514.0
HKD1_k127_4542853_1 A G-specific adenine glycosylase K03574,K03575 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000003546 274.0
HKD1_k127_4542853_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000001078 261.0
HKD1_k127_4542853_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000008534 201.0
HKD1_k127_4542853_4 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000001877 173.0
HKD1_k127_4549976_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 4.01e-225 713.0
HKD1_k127_4549976_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 474.0
HKD1_k127_4549976_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 383.0
HKD1_k127_4549976_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 352.0
HKD1_k127_4549976_4 4-phosphoerythronate dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 325.0
HKD1_k127_4549976_5 COG0698 Ribose 5-phosphate isomerase RpiB K01808 - 5.3.1.6 0.00000000000000000000000000000000000000001518 165.0
HKD1_k127_4549976_6 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000065 114.0
HKD1_k127_4549976_7 Protein of unknown function, DUF485 - - - 0.000000000000000000000189 109.0
HKD1_k127_4549976_8 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000001761 85.0
HKD1_k127_4559653_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.731e-231 735.0
HKD1_k127_4559653_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 323.0
HKD1_k127_4559653_2 Cytidylyltransferase K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000002264 258.0
HKD1_k127_4579362_0 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 331.0
HKD1_k127_4579362_1 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 322.0
HKD1_k127_4579362_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000002404 218.0
HKD1_k127_4579362_3 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000004706 110.0
HKD1_k127_4579362_4 membrane - - - 0.000000000000004407 90.0
HKD1_k127_4579362_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.000000000000004739 80.0
HKD1_k127_4579362_6 Heat shock protein DnaJ domain protein - - - 0.0000000000000817 83.0
HKD1_k127_4579362_7 Predicted membrane protein (DUF2339) - - - 0.000000007257 68.0
HKD1_k127_4579362_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03591 - - 0.00007967 53.0
HKD1_k127_4616524_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 503.0
HKD1_k127_4616524_2 Belongs to the ATCase OTCase family - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000002912 126.0
HKD1_k127_4616524_3 PFAM von Willebrand factor type A - - - 0.0000000000000709 83.0
HKD1_k127_4618624_0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term - - - 1.082e-294 931.0
HKD1_k127_4618624_1 Cysteine-rich domain K00113 - 1.1.5.3 2.544e-201 637.0
HKD1_k127_4618624_2 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 602.0
HKD1_k127_4618624_3 COGs COG4299 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 457.0
HKD1_k127_4618624_4 TonB-dependent Receptor Plug K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007095 286.0
HKD1_k127_4618624_5 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000003595 231.0
HKD1_k127_4618624_6 Rubrerythrin - - - 0.00000000000000000000000000000000000000001556 153.0
HKD1_k127_4618624_7 Domain of unknown function (DUF5107) - - - 0.0000000000001588 81.0
HKD1_k127_4639553_0 Belongs to the glycosyl hydrolase 28 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 509.0
HKD1_k127_4639553_1 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 361.0
HKD1_k127_4639553_2 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 330.0
HKD1_k127_4639553_3 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000001506 135.0
HKD1_k127_4639553_4 ABC-type cobalt transport system ATPase component K02006 - - 0.000000000000000006878 85.0
HKD1_k127_4639553_5 Domain of unknown function (DUF4861) K01051 - 3.1.1.11 0.00000009682 56.0
HKD1_k127_4707566_0 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 385.0
HKD1_k127_4707566_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000009042 173.0
HKD1_k127_4707566_2 ResB-like family - - - 0.000000000000000000000000000000007577 145.0
HKD1_k127_4707566_3 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000004374 102.0
HKD1_k127_4707566_4 Forkhead associated domain - - - 0.000000000002351 78.0
HKD1_k127_4707566_5 Dimerisation domain of Zinc Transporter - - - 0.000000009502 60.0
HKD1_k127_4726576_0 AcrB/AcrD/AcrF family - - - 0.0 1229.0
HKD1_k127_4726576_1 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0000000000000000000004301 106.0
HKD1_k127_4726576_2 HlyD family secretion protein - - - 0.00000000000000001324 92.0
HKD1_k127_473309_0 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 388.0
HKD1_k127_473309_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009725 284.0
HKD1_k127_473309_2 Polysaccharide biosynthesis protein K01711,K15856 - 1.1.1.281,4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000349 285.0
HKD1_k127_473309_3 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.00000000000000000000000000000000000000000000000000000000000001329 241.0
HKD1_k127_473309_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000002201 98.0
HKD1_k127_4746675_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 366.0
HKD1_k127_4746675_1 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000005747 208.0
HKD1_k127_4746675_2 Protein of unknown function, DUF393 - - - 0.000000000000000001047 101.0
HKD1_k127_4746675_3 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000001813 89.0
HKD1_k127_4746675_4 Tetratricopeptide repeat - - - 0.0002788 53.0
HKD1_k127_4747325_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.69e-200 647.0
HKD1_k127_4747325_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 516.0
HKD1_k127_4747325_2 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 311.0
HKD1_k127_4747325_3 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006893 283.0
HKD1_k127_4747325_4 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000001985 257.0
HKD1_k127_4747325_5 MarR family - - - 0.00000000000000000000000000000000000000000000000000000000003287 209.0
HKD1_k127_4747325_6 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000000000000000000307 185.0
HKD1_k127_4747325_7 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000003981 191.0
HKD1_k127_4747325_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000003618 100.0
HKD1_k127_4751244_0 Cytochrome c554 and c-prime - - - 2.63e-251 793.0
HKD1_k127_4751244_1 ASPIC and UnbV - - - 2.919e-203 676.0
HKD1_k127_4751244_2 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 319.0
HKD1_k127_4783288_0 phospholipase C K01114 - 3.1.4.3 9.855e-204 651.0
HKD1_k127_4783288_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 311.0
HKD1_k127_4783288_2 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001522 268.0
HKD1_k127_4783288_3 methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000002742 241.0
HKD1_k127_4783288_4 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000003935 227.0
HKD1_k127_4783288_5 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000002573 131.0
HKD1_k127_4783288_6 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.00000000000000000009383 98.0
HKD1_k127_4791275_0 xanthine dehydrogenase activity - - - 2.083e-306 951.0
HKD1_k127_4791275_1 CO dehydrogenase flavoprotein C-terminal domain K13479 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 342.0
HKD1_k127_4791275_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00207,K12527,K17723 - 1.3.1.1,1.3.1.2,1.97.1.9 0.000000000000000000000000000000000000000002607 162.0
HKD1_k127_4791275_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000001374 138.0
HKD1_k127_4812598_0 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 406.0
HKD1_k127_4812598_1 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000004131 186.0
HKD1_k127_4812598_2 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000003051 143.0
HKD1_k127_4812598_3 Protein of unknown function (DUF962) - - - 0.0000000000000000000000000000003547 125.0
HKD1_k127_4812598_4 - - - - 0.00000000000001344 85.0
HKD1_k127_4893688_0 TLC ATP/ADP transporter K03301 - - 0.0000000000000000000000000000000000000000000000000000000001267 233.0
HKD1_k127_4893688_1 Calcineurin-like phosphoesterase - - - 0.000000001397 69.0
HKD1_k127_4897781_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000536 230.0
HKD1_k127_4897781_1 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000005349 82.0
HKD1_k127_4897781_2 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000003977 57.0
HKD1_k127_4947644_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002378 273.0
HKD1_k127_4947644_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000002049 201.0
HKD1_k127_4947644_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000007709 173.0
HKD1_k127_4947644_3 TPM domain - - - 0.00000000000000000000000000000000006845 138.0
HKD1_k127_4947644_4 AI-2E family transporter - - - 0.00000000000000000000000000000000009474 149.0
HKD1_k127_4947644_5 ATP synthesis coupled proton transport K02109 - - 0.00000000000000000000000001003 116.0
HKD1_k127_4947644_6 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000002884 92.0
HKD1_k127_4947644_7 - - - - 0.000000004758 67.0
HKD1_k127_4974684_0 PFAM LmbE family protein K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 604.0
HKD1_k127_4974684_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 431.0
HKD1_k127_4974684_2 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000004129 224.0
HKD1_k127_5022163_0 PFAM ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 358.0
HKD1_k127_5022163_1 Transport permease protein K01992 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 317.0
HKD1_k127_5022163_2 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 330.0
HKD1_k127_5022163_3 Protein of unknown function (DUF4038) - - - 0.00000000000000000000000000000000000216 141.0
HKD1_k127_5022163_4 Outer membrane efflux protein - - - 0.000000001118 66.0
HKD1_k127_5057662_0 Belongs to the glycosyl hydrolase 2 family K01192 - 3.2.1.25 2.66e-258 822.0
HKD1_k127_5057662_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009405,GO:0009605,GO:0009607,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0035821,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043207,GO:0043492,GO:0043952,GO:0044003,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0075136,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 2.776e-247 787.0
HKD1_k127_5057662_10 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007791 254.0
HKD1_k127_5057662_11 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000006542 218.0
HKD1_k127_5057662_12 DinB family - - - 0.0000000000000000000000000000000000000000711 156.0
HKD1_k127_5057662_13 - - - - 0.0000000000000000000000000000000000000001689 161.0
HKD1_k127_5057662_14 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000005095 163.0
HKD1_k127_5057662_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000009783 139.0
HKD1_k127_5057662_16 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000001379 119.0
HKD1_k127_5057662_17 peptidyl-tyrosine sulfation - - - 0.00000000000000000003366 101.0
HKD1_k127_5057662_18 4-amino-4-deoxy-L-arabinose transferase activity K16648 - - 0.00000000000000000008395 101.0
HKD1_k127_5057662_19 DinB family - - - 0.000000000000000001744 100.0
HKD1_k127_5057662_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 474.0
HKD1_k127_5057662_20 Major Facilitator Superfamily - - - 0.000001531 56.0
HKD1_k127_5057662_3 COG0076 Glutamate decarboxylase and related PLP-dependent proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 440.0
HKD1_k127_5057662_4 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 368.0
HKD1_k127_5057662_5 Peptidase inhibitor I9 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 351.0
HKD1_k127_5057662_6 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 319.0
HKD1_k127_5057662_7 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 284.0
HKD1_k127_5057662_8 choline dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002274 291.0
HKD1_k127_5057662_9 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000002491 276.0
HKD1_k127_50594_0 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 372.0
HKD1_k127_50594_1 mannose-6-phosphate isomerase, class I K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 344.0
HKD1_k127_50594_10 dockerin type - - - 0.00000000000000000000153 106.0
HKD1_k127_50594_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 312.0
HKD1_k127_50594_3 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 289.0
HKD1_k127_50594_4 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006169 266.0
HKD1_k127_50594_5 - - - - 0.000000000000000000000000000000000000000000000000000001583 198.0
HKD1_k127_50594_6 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000003899 187.0
HKD1_k127_50594_7 Responsible for synthesis of pseudouridine from uracil K06179,K06180 - 5.4.99.23,5.4.99.24 0.0000000000000000000000000000000000000000000009122 178.0
HKD1_k127_50594_8 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000004097 163.0
HKD1_k127_50594_9 Domain of unknown function (DUF1820) - - - 0.0000000000000000000000000000000236 128.0
HKD1_k127_5069178_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 542.0
HKD1_k127_5069178_1 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 511.0
HKD1_k127_5069178_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 481.0
HKD1_k127_5069178_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 486.0
HKD1_k127_5069178_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008846 329.0
HKD1_k127_5069178_5 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 308.0
HKD1_k127_5069178_6 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000003443 136.0
HKD1_k127_5069178_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000001066 127.0
HKD1_k127_5069178_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000001198 109.0
HKD1_k127_5069178_9 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000001763 109.0
HKD1_k127_5108854_0 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 394.0
HKD1_k127_5108854_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 349.0
HKD1_k127_5108854_2 short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000001447 220.0
HKD1_k127_5108854_3 Integral membrane protein CcmA involved in cell shape determination - - - 0.0001084 52.0
HKD1_k127_5114048_0 ASPIC and UnbV - - - 8.087e-263 854.0
HKD1_k127_5114048_1 lysine biosynthetic process via aminoadipic acid - - - 6.491e-204 662.0
HKD1_k127_5114048_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 522.0
HKD1_k127_5114048_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 516.0
HKD1_k127_5114048_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 421.0
HKD1_k127_5114048_5 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 385.0
HKD1_k127_5114048_6 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 400.0
HKD1_k127_5114048_8 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000006715 111.0
HKD1_k127_5114048_9 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000004437 60.0
HKD1_k127_51198_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1491.0
HKD1_k127_51198_1 Two component regulator propeller K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 545.0
HKD1_k127_51198_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000109 228.0
HKD1_k127_51198_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000001855 216.0
HKD1_k127_51198_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000007048 128.0
HKD1_k127_5132318_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 424.0
HKD1_k127_5132318_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 383.0
HKD1_k127_5132318_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 372.0
HKD1_k127_5132318_3 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.00000000000000000000000000000002264 145.0
HKD1_k127_5132318_4 - - - - 0.0000000000000000000000000001441 133.0
HKD1_k127_5132318_5 Protein of unknown function (DUF2662) - - - 0.0000000000004591 81.0
HKD1_k127_5132318_6 Elongation factor SelB, winged helix K03833 - - 0.00000000000391 67.0
HKD1_k127_5132318_7 response regulator - - - 0.0003561 48.0
HKD1_k127_5148954_0 Zn-dependent hydrolases including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009151 412.0
HKD1_k127_5148954_1 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 392.0
HKD1_k127_5148954_2 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 313.0
HKD1_k127_5148954_3 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000005329 247.0
HKD1_k127_5148954_4 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.0000000000000000000000000000000000000000000000000000000004507 221.0
HKD1_k127_5148954_5 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000003634 202.0
HKD1_k127_5148954_6 Bacterial membrane protein, YfhO - - - 0.00000000000000008122 94.0
HKD1_k127_5162119_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000003255 201.0
HKD1_k127_5162119_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000001162 90.0
HKD1_k127_5171077_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 584.0
HKD1_k127_5171077_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 580.0
HKD1_k127_5171077_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 466.0
HKD1_k127_5171077_3 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 396.0
HKD1_k127_5171077_4 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000004158 259.0
HKD1_k127_5171077_5 PFAM Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000132 172.0
HKD1_k127_5171077_6 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000003182 70.0
HKD1_k127_5171077_7 PFAM peptidase S1 and S6 chymotrypsin Hap K04771 - 3.4.21.107 0.0009136 53.0
HKD1_k127_5180473_0 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 342.0
HKD1_k127_5180473_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000004699 108.0
HKD1_k127_5180473_2 Bacterial membrane protein YfhO - - - 0.00000000000001836 87.0
HKD1_k127_5192409_0 belongs to the nudix hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 320.0
HKD1_k127_5192409_1 Inositol monophosphatase K01092,K05602,K18649 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008934,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016053,GO:0016137,GO:0016138,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052745,GO:0052803,GO:0052834,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659 3.1.3.15,3.1.3.25,3.1.3.93 0.0000000000000000000000000000000000000000000000000000000000000000000001869 248.0
HKD1_k127_5192409_2 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000001458 228.0
HKD1_k127_5192409_3 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000004967 235.0
HKD1_k127_5192409_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000009285 184.0
HKD1_k127_5192409_5 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.000000000000000000000000000000000006118 148.0
HKD1_k127_5192409_6 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000538 131.0
HKD1_k127_5192409_7 subfamily IA, variant 1 K07025 - - 0.000000000000000000000000007554 119.0
HKD1_k127_5192409_9 Translation initiation factor 1A / IF-1 K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000003645 91.0
HKD1_k127_5216330_0 aminoacyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000002589 227.0
HKD1_k127_5216330_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000001248 226.0
HKD1_k127_5216330_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000002963 191.0
HKD1_k127_5216330_3 AAA domain (Cdc48 subfamily) K03544 - - 0.00000000000000000000000000000000000000000003892 170.0
HKD1_k127_5216330_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000001877 178.0
HKD1_k127_5216330_5 Peptidase M50 - - - 0.00000000000000000000000000000000000000001161 171.0
HKD1_k127_522242_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 391.0
HKD1_k127_522242_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000472 216.0
HKD1_k127_522242_2 Histidine kinase K02668,K07709,K07710 - 2.7.13.3 0.00000000000000000000000000000000000103 153.0
HKD1_k127_522242_3 - - - - 0.000000000000000000000001688 109.0
HKD1_k127_5223259_0 PFAM ABC transporter transmembrane K06147 - - 8.533e-205 647.0
HKD1_k127_5223259_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 8.818e-199 639.0
HKD1_k127_5223259_2 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009295 568.0
HKD1_k127_5223259_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 483.0
HKD1_k127_5223259_4 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 292.0
HKD1_k127_5223259_5 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000001462 153.0
HKD1_k127_5223259_6 Rhomboid family - - - 0.00000000000000000000000000000000002374 152.0
HKD1_k127_5223259_7 ABC-2 family transporter protein K19341 - - 0.0001746 44.0
HKD1_k127_5235922_0 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 3.069e-234 733.0
HKD1_k127_5235922_1 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 516.0
HKD1_k127_5235922_2 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 492.0
HKD1_k127_5248623_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 540.0
HKD1_k127_5248623_1 flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 506.0
HKD1_k127_5248623_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 431.0
HKD1_k127_5248623_3 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000009797 247.0
HKD1_k127_5248623_4 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000001949 147.0
HKD1_k127_5248623_5 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000001065 122.0
HKD1_k127_5248623_6 - - - - 0.00000000000000000000000004413 117.0
HKD1_k127_5248623_7 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000123 106.0
HKD1_k127_5248623_8 - - - - 0.000000000000002894 85.0
HKD1_k127_5252810_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000004134 123.0
HKD1_k127_5252810_1 - - - - 0.000002217 58.0
HKD1_k127_5253496_0 Aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 593.0
HKD1_k127_5253496_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 442.0
HKD1_k127_5253496_10 Acetyltransferase (GNAT) domain - - - 0.00001668 54.0
HKD1_k127_5253496_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000002378 243.0
HKD1_k127_5253496_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000005241 214.0
HKD1_k127_5253496_4 - K07018 - - 0.00000000000000000000000000000000000000000000000001718 189.0
HKD1_k127_5253496_5 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000002133 176.0
HKD1_k127_5253496_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000002012 107.0
HKD1_k127_5253496_7 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000001271 74.0
HKD1_k127_5253496_8 Two component transcriptional regulator, winged helix family K07659 - - 0.000000007863 62.0
HKD1_k127_5253496_9 Periplasmic binding protein-like domain K10439 - - 0.0000007423 60.0
HKD1_k127_5262787_0 Polysulphide reductase, NrfD K00185 - - 1.541e-210 673.0
HKD1_k127_5262787_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 535.0
HKD1_k127_5262787_10 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007517 244.0
HKD1_k127_5262787_11 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000127 250.0
HKD1_k127_5262787_12 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001559 251.0
HKD1_k127_5262787_13 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000001344 244.0
HKD1_k127_5262787_14 protein tyrosine kinase activity K03593 - - 0.000000000000000000000000000000000000000000000000000008384 200.0
HKD1_k127_5262787_15 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000009788 209.0
HKD1_k127_5262787_16 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000002389 201.0
HKD1_k127_5262787_17 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000003545 198.0
HKD1_k127_5262787_18 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000005881 191.0
HKD1_k127_5262787_19 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000001808 150.0
HKD1_k127_5262787_2 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 492.0
HKD1_k127_5262787_20 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000007296 138.0
HKD1_k127_5262787_21 Proto-chlorophyllide reductase 57 kd subunit - - - 0.0000000000000000000001624 109.0
HKD1_k127_5262787_22 OsmC-like protein K07397 - - 0.00000000000000000351 97.0
HKD1_k127_5262787_23 Putative phosphatase (DUF442) - - - 0.00000000000000002784 89.0
HKD1_k127_5262787_24 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000008797 73.0
HKD1_k127_5262787_3 Proto-chlorophyllide reductase 57 kD subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 348.0
HKD1_k127_5262787_4 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 331.0
HKD1_k127_5262787_5 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 304.0
HKD1_k127_5262787_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 301.0
HKD1_k127_5262787_7 rubredoxin K22405 - 1.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009239 306.0
HKD1_k127_5262787_8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002252 277.0
HKD1_k127_5262787_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000156 270.0
HKD1_k127_5268167_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.933e-248 790.0
HKD1_k127_5268167_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 473.0
HKD1_k127_5268167_10 shape-determining protein MreD K03571 - - 0.0006203 52.0
HKD1_k127_5268167_2 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 445.0
HKD1_k127_5268167_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009199 289.0
HKD1_k127_5268167_4 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000003163 153.0
HKD1_k127_5268167_5 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000008847 156.0
HKD1_k127_5268167_6 PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.000000000000000000000000001428 126.0
HKD1_k127_5268167_7 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.0000000000000000001425 100.0
HKD1_k127_5268167_8 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000004166 97.0
HKD1_k127_5268167_9 outer membrane autotransporter barrel domain protein - - - 0.0004012 53.0
HKD1_k127_5335489_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1303.0
HKD1_k127_5386091_0 Anticodon-binding domain of tRNA K01873 - 6.1.1.9 5.492e-291 908.0
HKD1_k127_5386091_1 Metallo-beta-lactamase superfamily K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 322.0
HKD1_k127_5386091_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 312.0
HKD1_k127_5386091_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000004154 222.0
HKD1_k127_5386091_4 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000002478 166.0
HKD1_k127_5386091_5 outer membrane autotransporter barrel domain protein - - - 0.0000000000000000005825 101.0
HKD1_k127_5386091_6 peptidyl-tyrosine sulfation - - - 0.00000000000002563 87.0
HKD1_k127_5386091_7 Domain of unknown function (DUF1844) - - - 0.0000003412 64.0
HKD1_k127_5429115_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1433.0
HKD1_k127_5429115_1 efflux transmembrane transporter activity K12340 - - 0.00000000000000000000000000000000000000000000000255 195.0
HKD1_k127_54438_0 Glycosyl hydrolase family 3 K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 358.0
HKD1_k127_54438_1 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000007947 181.0
HKD1_k127_54438_2 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000009981 157.0
HKD1_k127_54438_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000003437 103.0
HKD1_k127_54438_4 - - - - 0.000000000003547 66.0
HKD1_k127_54438_5 Glutaredoxin K03676 - - 0.0000000004352 61.0
HKD1_k127_54438_6 - - - - 0.00000001672 60.0
HKD1_k127_54438_7 - - - - 0.00005907 53.0
HKD1_k127_5470583_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003183 304.0
HKD1_k127_5470583_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001634 293.0
HKD1_k127_5470583_2 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000244 250.0
HKD1_k127_5470583_3 PFAM Type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000001108 243.0
HKD1_k127_5470583_4 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000007275 213.0
HKD1_k127_5470583_5 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000703 170.0
HKD1_k127_5482084_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.026e-264 826.0
HKD1_k127_5482084_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000002 150.0
HKD1_k127_5490017_0 Putative oxidoreductase C terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 410.0
HKD1_k127_5490017_1 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009416 325.0
HKD1_k127_5490017_2 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007022 307.0
HKD1_k127_5490017_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000002265 226.0
HKD1_k127_5490017_4 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000001014 186.0
HKD1_k127_5492094_0 Glycosyl hydrolases family 2, TIM barrel domain K01195 - 3.2.1.31 3.316e-203 650.0
HKD1_k127_5492094_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 413.0
HKD1_k127_5492094_2 Ferric uptake regulator family K03711,K09825 - - 0.0000000000000000000000000000000000000000003202 162.0
HKD1_k127_5492094_3 energy transducer activity K03832 - - 0.000000000000000000000000000000000000000001536 176.0
HKD1_k127_5492094_4 Penicillinase repressor - - - 0.000000000000000000000000000000000000009939 149.0
HKD1_k127_5492094_5 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000009638 51.0
HKD1_k127_5536750_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1143.0
HKD1_k127_5536750_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 355.0
HKD1_k127_5536750_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000001027 232.0
HKD1_k127_5613622_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 424.0
HKD1_k127_5613622_1 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 409.0
HKD1_k127_5613622_2 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 369.0
HKD1_k127_5620577_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000002297 236.0
HKD1_k127_5620577_1 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000001409 196.0
HKD1_k127_5620577_2 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000006123 138.0
HKD1_k127_5620577_3 CYTH K05873 - 4.6.1.1 0.00000000000000000000000000007745 123.0
HKD1_k127_5628336_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003077 289.0
HKD1_k127_5628336_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000001047 78.0
HKD1_k127_5635992_0 response regulator K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 520.0
HKD1_k127_5635992_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 396.0
HKD1_k127_5635992_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000005515 194.0
HKD1_k127_5635992_3 response regulator K02481,K07713 - - 0.000000000000000000003867 100.0
HKD1_k127_5635992_4 TIGRFAM thioredoxin K03671 - - 0.000000000000000005796 89.0
HKD1_k127_5664395_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.509e-224 715.0
HKD1_k127_5664395_1 NUBPL iron-transfer P-loop NTPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 325.0
HKD1_k127_5664395_10 Polymer-forming cytoskeletal - - - 0.000000000000000002 98.0
HKD1_k127_5664395_11 R3H domain protein K06346 - - 0.00000000000000000454 98.0
HKD1_k127_5664395_12 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000004947 89.0
HKD1_k127_5664395_13 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000006248 72.0
HKD1_k127_5664395_14 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000004189 71.0
HKD1_k127_5664395_2 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 301.0
HKD1_k127_5664395_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000495 267.0
HKD1_k127_5664395_4 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000004303 228.0
HKD1_k127_5664395_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000001795 185.0
HKD1_k127_5664395_6 - - - - 0.000000000000000000000000000000000001803 141.0
HKD1_k127_5664395_7 ATP synthase K02115 - - 0.000000000000000000000000000009833 120.0
HKD1_k127_5664395_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000009746 104.0
HKD1_k127_5664395_9 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000001231 93.0
HKD1_k127_5673030_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001604 269.0
HKD1_k127_5673030_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000009847 189.0
HKD1_k127_5704933_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 3.32e-276 876.0
HKD1_k127_5704933_1 Domain of unknown function (DUF5107) - - - 2.491e-199 661.0
HKD1_k127_5704933_2 Homoserine O-succinyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 494.0
HKD1_k127_5704933_3 ACT domain K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 324.0
HKD1_k127_5704933_4 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000007008 79.0
HKD1_k127_5708313_0 Proton-conducting membrane transporter K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 368.0
HKD1_k127_5708313_1 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000001921 182.0
HKD1_k127_5708313_2 Hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000002297 154.0
HKD1_k127_5708313_3 dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases - - - 0.00003071 57.0
HKD1_k127_5747928_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1266.0
HKD1_k127_5747928_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 438.0
HKD1_k127_5747928_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 355.0
HKD1_k127_5747928_3 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 293.0
HKD1_k127_5747928_4 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006191 267.0
HKD1_k127_5747928_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000009822 246.0
HKD1_k127_5747928_6 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000373 246.0
HKD1_k127_5747928_7 membrane - - - 0.00000000000000000000000000000000000002477 154.0
HKD1_k127_5747928_8 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000003258 143.0
HKD1_k127_5747928_9 - K01992 - - 0.00000000000004873 86.0
HKD1_k127_5846049_0 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 550.0
HKD1_k127_5846049_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 400.0
HKD1_k127_5846049_10 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000003086 221.0
HKD1_k127_5846049_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000007647 78.0
HKD1_k127_5846049_2 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 413.0
HKD1_k127_5846049_3 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 363.0
HKD1_k127_5846049_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 363.0
HKD1_k127_5846049_5 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 357.0
HKD1_k127_5846049_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 337.0
HKD1_k127_5846049_7 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001164 286.0
HKD1_k127_5846049_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000006112 244.0
HKD1_k127_5846049_9 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000285 235.0
HKD1_k127_589761_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0 1201.0
HKD1_k127_589761_1 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 379.0
HKD1_k127_589761_2 Protein of unknown function (DUF2911) - - - 0.000000000000000000003072 102.0
HKD1_k127_5902910_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 425.0
HKD1_k127_5902910_1 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009611 298.0
HKD1_k127_5902910_2 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000006231 177.0
HKD1_k127_5902910_3 Putative zinc- or iron-chelating domain K18475 - - 0.000000000003853 78.0
HKD1_k127_5902910_4 Amidohydrolase family - - - 0.00006612 46.0
HKD1_k127_5902910_5 - - - - 0.0003039 53.0
HKD1_k127_5907297_0 Sortilin, neurotensin receptor 3, - - - 0.0 1284.0
HKD1_k127_5907297_1 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 6.108e-256 810.0
HKD1_k127_5907297_2 - - - - 0.0000000000000000000000000000000000000000000000000000325 201.0
HKD1_k127_5907297_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000003887 158.0
HKD1_k127_5907297_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000001923 138.0
HKD1_k127_5907297_5 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000005859 76.0
HKD1_k127_5907297_6 Protein involved in meta-pathway of phenol degradation - - - 0.000000003152 68.0
HKD1_k127_5916042_0 Class II Aldolase and Adducin N-terminal domain K00001,K01629 - 1.1.1.1,4.1.2.19 0.0 1022.0
HKD1_k127_5916042_1 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 8.774e-262 834.0
HKD1_k127_5916042_2 Alpha-L-rhamnosidase N-terminal domain K05989 - 3.2.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 459.0
HKD1_k127_5944063_0 elongation factor G K02355 - - 4.119e-237 752.0
HKD1_k127_5944063_1 protein kinase activity - - - 0.000000000000000000001138 107.0
HKD1_k127_5944063_2 Pilus assembly protein K02662 - - 0.00004848 55.0
HKD1_k127_5965434_0 PFAM Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 482.0
HKD1_k127_5965434_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 479.0
HKD1_k127_5965434_2 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003077 252.0
HKD1_k127_5965434_3 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003313 235.0
HKD1_k127_5965434_4 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000002002 168.0
HKD1_k127_5965434_5 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000003453 96.0
HKD1_k127_5965434_6 - - - - 0.0000000000007098 74.0
HKD1_k127_6004744_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 343.0
HKD1_k127_6011530_0 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 587.0
HKD1_k127_6011530_1 K transport systems K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 332.0
HKD1_k127_6011530_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000001425 227.0
HKD1_k127_6011530_3 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000001399 183.0
HKD1_k127_6011530_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000003848 181.0
HKD1_k127_6011530_5 Glucose-regulated metallo-peptidase M90 K09933 - - 0.0000000000000000000000000000000000000000000001138 187.0
HKD1_k127_6011530_6 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000001938 164.0
HKD1_k127_6011530_7 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000003926 112.0
HKD1_k127_6011530_8 Endonuclease exonuclease phosphatase family - - - 0.000000000000004472 77.0
HKD1_k127_6057008_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 304.0
HKD1_k127_6057008_1 TrkA-N domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000135 295.0
HKD1_k127_6057008_2 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000000000003357 211.0
HKD1_k127_6057008_3 Cyclic nucleotide binding domain protein - - - 0.00000000000000000002881 104.0
HKD1_k127_6095064_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 559.0
HKD1_k127_6095064_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 441.0
HKD1_k127_6095064_2 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 354.0
HKD1_k127_6095064_3 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001434 273.0
HKD1_k127_6095064_4 surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000002152 271.0
HKD1_k127_6095064_5 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000004319 205.0
HKD1_k127_6095064_6 PFAM Methyltransferase domain K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000000167 187.0
HKD1_k127_6095064_7 Biotin-requiring enzyme - - - 0.00000000000000000000004189 106.0
HKD1_k127_6095064_8 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00001879 54.0
HKD1_k127_6095064_9 PFAM glycosyl transferase group 1 - - - 0.00002093 57.0
HKD1_k127_6106956_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 467.0
HKD1_k127_6106956_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 449.0
HKD1_k127_6106956_10 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000009412 160.0
HKD1_k127_6106956_11 general secretion pathway protein K02456,K02650 - - 0.00000000000000003936 91.0
HKD1_k127_6106956_12 phosphorelay sensor kinase activity K07638,K07673,K21009 - 2.7.13.3 0.0000000000005125 82.0
HKD1_k127_6106956_13 TonB-linked outer membrane protein, SusC RagA family - - - 0.00005225 54.0
HKD1_k127_6106956_2 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 429.0
HKD1_k127_6106956_3 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 409.0
HKD1_k127_6106956_4 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002782 285.0
HKD1_k127_6106956_5 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000003815 267.0
HKD1_k127_6106956_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000001171 245.0
HKD1_k127_6106956_7 Amidohydrolase family K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000009897 245.0
HKD1_k127_6106956_8 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000001093 207.0
HKD1_k127_6106956_9 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000001427 184.0
HKD1_k127_6107388_0 response regulator, receiver K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009313 467.0
HKD1_k127_6107388_1 isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 404.0
HKD1_k127_6107388_10 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000001321 171.0
HKD1_k127_6107388_11 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000001852 179.0
HKD1_k127_6107388_12 PFAM Haloacid dehalogenase domain protein hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000006712 159.0
HKD1_k127_6107388_13 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000003762 160.0
HKD1_k127_6107388_14 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000004204 134.0
HKD1_k127_6107388_15 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000001492 118.0
HKD1_k127_6107388_16 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000007281 128.0
HKD1_k127_6107388_17 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000005911 105.0
HKD1_k127_6107388_18 PFAM Peptidase family M28 - - - 0.0000000000000001419 93.0
HKD1_k127_6107388_19 Conserved protein - - - 0.000003781 49.0
HKD1_k127_6107388_2 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 353.0
HKD1_k127_6107388_3 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 344.0
HKD1_k127_6107388_4 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 322.0
HKD1_k127_6107388_5 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001979 267.0
HKD1_k127_6107388_6 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000003432 235.0
HKD1_k127_6107388_7 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000003367 216.0
HKD1_k127_6107388_8 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000001383 217.0
HKD1_k127_6107388_9 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000004419 196.0
HKD1_k127_6123857_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 544.0
HKD1_k127_6135753_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 382.0
HKD1_k127_6135753_1 PFAM ThiJ PfpI domain protein K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 333.0
HKD1_k127_6135753_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000008194 69.0
HKD1_k127_6150528_0 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 553.0
HKD1_k127_6150528_1 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000003365 206.0
HKD1_k127_6150528_2 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000002767 149.0
HKD1_k127_6150528_3 O-Antigen ligase K02847 - - 0.0000000000000000000000000000000000005036 157.0
HKD1_k127_6150528_4 - - - - 0.00000000000007988 80.0
HKD1_k127_6162647_0 domain protein - - - 1.491e-217 687.0
HKD1_k127_6162647_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 363.0
HKD1_k127_6162647_2 hydroperoxide reductase activity K01607 - 4.1.1.44 0.000000000000000000000000000000000704 132.0
HKD1_k127_6162647_3 - - - - 0.000000000000000000000000000000304 126.0
HKD1_k127_6164756_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1184.0
HKD1_k127_6164756_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 443.0
HKD1_k127_6164756_2 Haloacid dehalogenase-like hydrolase K02566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 293.0
HKD1_k127_6164756_3 Belongs to the MIP aquaporin (TC 1.A.8) family K03441 GO:0000003,GO:0000322,GO:0000323,GO:0000324,GO:0000746,GO:0000747,GO:0003674,GO:0005215,GO:0005372,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006833,GO:0006846,GO:0008150,GO:0008643,GO:0009987,GO:0015144,GO:0015166,GO:0015168,GO:0015250,GO:0015254,GO:0015267,GO:0015318,GO:0015698,GO:0015700,GO:0015711,GO:0015718,GO:0015791,GO:0015793,GO:0015849,GO:0015850,GO:0015893,GO:0016020,GO:0016021,GO:0019953,GO:0022414,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034219,GO:0042044,GO:0042221,GO:0042493,GO:0042891,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0044703,GO:0044764,GO:0046685,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071702,GO:0071944,GO:1901618 - 0.00000000000000000000000000000000000000000000000004762 194.0
HKD1_k127_6164756_4 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000193 151.0
HKD1_k127_6172027_0 Bacterial alpha-L-rhamnosidase C-terminal domain - - - 4.668e-248 795.0
HKD1_k127_6172027_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 430.0
HKD1_k127_6172027_2 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 370.0
HKD1_k127_6172027_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 336.0
HKD1_k127_6172027_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000009273 184.0
HKD1_k127_6172027_5 Domain of unknown function (DUF4380) - - - 0.000000000000000000000000000000000000000000001632 180.0
HKD1_k127_6172027_6 Antirepressor regulating drug resistance - - - 0.00000000000000000000000000000000000000000001896 175.0
HKD1_k127_6172027_7 Penicillinase repressor - - - 0.0000000000000000000000000000000001832 136.0
HKD1_k127_6172027_8 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.00000000000000000000006533 109.0
HKD1_k127_6204660_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 457.0
HKD1_k127_6204660_1 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 308.0
HKD1_k127_6207843_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 3.809e-271 843.0
HKD1_k127_6207843_1 metallopeptidase activity K01179 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0033946,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0052736,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.4 9.015e-228 719.0
HKD1_k127_6207843_10 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000004979 121.0
HKD1_k127_6207843_11 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000003152 130.0
HKD1_k127_6207843_12 Transcriptional regulator K07729 - - 0.0000000000000000000000321 109.0
HKD1_k127_6207843_2 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 550.0
HKD1_k127_6207843_3 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 489.0
HKD1_k127_6207843_4 acetolactate synthase K01576,K01652 - 2.2.1.6,4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 410.0
HKD1_k127_6207843_5 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 402.0
HKD1_k127_6207843_6 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 324.0
HKD1_k127_6207843_8 Bacitracin ABC transporter, ATP-binding protein K01990,K19309 - - 0.000000000000000000000000000000000000000000000000000000000004717 221.0
HKD1_k127_6207843_9 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000000001096 169.0
HKD1_k127_6209203_0 LeuA allosteric (dimerisation) domain K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 349.0
HKD1_k127_6209203_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 349.0
HKD1_k127_6209203_2 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 306.0
HKD1_k127_6209203_3 Anaphase-promoting complex subunit 4 WD40 domain - - - 0.000000000000000000000000000000001889 141.0
HKD1_k127_6215187_0 peptidase K01415,K07386 - 3.4.24.71 1.931e-234 769.0
HKD1_k127_6215187_1 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 608.0
HKD1_k127_6215187_2 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 400.0
HKD1_k127_6215187_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003637 283.0
HKD1_k127_6215187_4 Transcriptional regulator - - - 0.00000000000000000000000000000009409 137.0
HKD1_k127_6215187_5 Late embryogenesis abundant protein - - - 0.0001692 55.0
HKD1_k127_6217783_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 578.0
HKD1_k127_6217783_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 489.0
HKD1_k127_6217783_2 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000001934 220.0
HKD1_k127_6217783_3 Carboxypeptidase regulatory-like domain - - - 0.00073 52.0
HKD1_k127_6254942_0 Domain of unknown function (DUF4132) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 407.0
HKD1_k127_6254942_1 - - - - 0.0000000000000000000000000000000003172 136.0
HKD1_k127_6255100_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 570.0
HKD1_k127_6255100_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 332.0
HKD1_k127_6255100_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 314.0
HKD1_k127_6255100_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000004341 274.0
HKD1_k127_6255100_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002148 247.0
HKD1_k127_6255100_5 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000001703 235.0
HKD1_k127_6255100_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000007115 117.0
HKD1_k127_6255100_7 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000008304 86.0
HKD1_k127_6284954_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 395.0
HKD1_k127_6284954_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03615,K05580 - 1.6.5.3 0.000000000000000000000000000000000000422 145.0
HKD1_k127_6284954_2 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000006894 139.0
HKD1_k127_6284954_3 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000008269 117.0
HKD1_k127_628874_0 amidohydrolase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 608.0
HKD1_k127_628874_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 569.0
HKD1_k127_628874_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 418.0
HKD1_k127_628874_3 UDP-glucose 4-epimerase activity K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 359.0
HKD1_k127_628874_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000002418 111.0
HKD1_k127_631225_0 PFAM short-chain dehydrogenase reductase SDR K15314 - - 0.0 1337.0
HKD1_k127_6330610_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 527.0
HKD1_k127_6330610_1 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 458.0
HKD1_k127_6330610_2 DinB superfamily K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007587 389.0
HKD1_k127_6330610_3 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000006118 267.0
HKD1_k127_6330610_4 ATPases associated with a variety of cellular activities K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000366 268.0
HKD1_k127_6330610_5 - - - - 0.000000000000000000000000000000000000000000000000000000001139 215.0
HKD1_k127_6330610_6 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000000000000001303 90.0
HKD1_k127_6330610_7 Transcriptional regulatory protein, C terminal - - - 0.000000000000001504 89.0
HKD1_k127_6352510_0 radical SAM domain protein K22318 - - 1.647e-195 636.0
HKD1_k127_6352510_1 SMART helicase c2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 557.0
HKD1_k127_6352510_11 - - - - 0.0006363 46.0
HKD1_k127_6352510_2 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 456.0
HKD1_k127_6352510_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 308.0
HKD1_k127_6352510_4 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000004937 188.0
HKD1_k127_6352510_5 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000006848 195.0
HKD1_k127_6352510_6 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000006265 163.0
HKD1_k127_6352510_7 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000001924 158.0
HKD1_k127_6352510_8 - - - - 0.0000001182 59.0
HKD1_k127_6352510_9 CHRD domain - - - 0.000003246 57.0
HKD1_k127_6369086_0 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 513.0
HKD1_k127_6369086_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 348.0
HKD1_k127_6369086_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 351.0
HKD1_k127_6369086_3 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 327.0
HKD1_k127_6369086_4 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002207 261.0
HKD1_k127_6369086_5 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002538 244.0
HKD1_k127_6369086_6 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000001779 239.0
HKD1_k127_6369086_7 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000004016 219.0
HKD1_k127_6369086_8 GMP synthase-glutamine amidotransferase - - - 0.00001713 58.0
HKD1_k127_6378725_0 Belongs to the CarB family K01955 - 6.3.5.5 2.998e-279 880.0
HKD1_k127_6378725_1 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000003813 207.0
HKD1_k127_6378725_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000003683 174.0
HKD1_k127_6378725_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000008432 166.0
HKD1_k127_6378725_4 esterase of the alpha-beta hydrolase K07001 - - 0.00000000000000000000000000000079 133.0
HKD1_k127_6378725_5 protein-disulfide reductase activity K05807 - - 0.00000000000000008648 92.0
HKD1_k127_6383484_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 416.0
HKD1_k127_6383484_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 382.0
HKD1_k127_6383484_2 Formyl transferase K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000001275 237.0
HKD1_k127_6383484_3 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000003408 181.0
HKD1_k127_6383484_4 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000001736 98.0
HKD1_k127_6387744_0 Belongs to the UPF0441 family - - - 1.67e-320 1010.0
HKD1_k127_6387744_1 Thiolase, C-terminal domain - - - 2.714e-196 619.0
HKD1_k127_6387744_2 DNA polymerase type-B family K02336 - 2.7.7.7 3.201e-194 634.0
HKD1_k127_6387744_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 603.0
HKD1_k127_6387744_4 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 333.0
HKD1_k127_6387744_5 LssY C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000005576 240.0
HKD1_k127_6387744_6 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000004871 180.0
HKD1_k127_6387744_7 acetylesterase activity - - - 0.0000000265 61.0
HKD1_k127_639431_0 Belongs to the glycosyl hydrolase 31 family K01811 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.177 1.149e-243 780.0
HKD1_k127_639431_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000001834 114.0
HKD1_k127_6417298_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 461.0
HKD1_k127_6417298_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 410.0
HKD1_k127_6417298_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 404.0
HKD1_k127_6417298_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000001664 167.0
HKD1_k127_6417298_4 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.00000000000000000000000000000000000007368 157.0
HKD1_k127_6417298_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000001939 144.0
HKD1_k127_6417298_6 - - - - 0.000000000000001889 83.0
HKD1_k127_6428280_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 565.0
HKD1_k127_6428280_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 479.0
HKD1_k127_6428280_2 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005189 284.0
HKD1_k127_6428280_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000004144 174.0
HKD1_k127_6470063_0 FAD binding domain K00481 - 1.14.13.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 563.0
HKD1_k127_6470063_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 525.0
HKD1_k127_6470063_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 325.0
HKD1_k127_6470063_3 3-oxoadipate enol-lactonase K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004408 270.0
HKD1_k127_6470063_4 Alpha/beta hydrolase family K01055,K14727 - 3.1.1.24,4.1.1.44 0.000000000000000000000000000000000000000001084 166.0
HKD1_k127_6470063_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000004569 57.0
HKD1_k127_6491017_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000429 53.0
HKD1_k127_6503046_0 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000006881 166.0
HKD1_k127_6503046_1 Histidine kinase - - - 0.00000000000000000000000000000000000000001293 177.0
HKD1_k127_6503046_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000401 124.0
HKD1_k127_6515213_0 Aminotransferase K14267,K14287 - 2.6.1.17,2.6.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 424.0
HKD1_k127_6515213_1 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000004121 98.0
HKD1_k127_6540122_0 4Fe-4S single cluster domain K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 587.0
HKD1_k127_6540122_1 PFAM Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 341.0
HKD1_k127_6540122_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 316.0
HKD1_k127_6540122_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000001704 188.0
HKD1_k127_6540122_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000275 141.0
HKD1_k127_6540122_5 ATP synthase delta (OSCP) subunit K02113 - - 0.0000000000000000000004586 100.0
HKD1_k127_6540122_6 ATP synthase subunit C K02110 - - 0.000000000000001778 91.0
HKD1_k127_6540122_7 Stage II K07315 - 3.1.3.3 0.0000000000001123 74.0
HKD1_k127_6610301_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 503.0
HKD1_k127_6610301_1 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 322.0
HKD1_k127_6663952_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 413.0
HKD1_k127_6663952_1 TIGRFAM arsenite-activated ATPase ArsA K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 381.0
HKD1_k127_6663952_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 369.0
HKD1_k127_6663952_3 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 334.0
HKD1_k127_6663952_4 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001111 263.0
HKD1_k127_6663952_5 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000002128 181.0
HKD1_k127_6663952_7 Chalcone isomerase-like - - - 0.0000000000005302 79.0
HKD1_k127_6682277_0 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 444.0
HKD1_k127_6682277_1 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007153 279.0
HKD1_k127_6682277_10 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000006139 80.0
HKD1_k127_6682277_11 Regulatory protein, FmdB family - - - 0.0000323 51.0
HKD1_k127_6682277_2 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001686 250.0
HKD1_k127_6682277_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000004357 213.0
HKD1_k127_6682277_4 Putative regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000142 199.0
HKD1_k127_6682277_5 - - - - 0.00000000000000000000000000000000000000000000001203 191.0
HKD1_k127_6682277_6 PFAM Lipocalin family protein K03098 - - 0.00000000000000000000000000000000000000000000002527 179.0
HKD1_k127_6682277_7 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0018130,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0019438,GO:0019538,GO:0033499,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042125,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046835,GO:0046872,GO:0046914,GO:0052573,GO:0052574,GO:0055086,GO:0070085,GO:0070569,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.7.12 0.0000000000000000000000000000000000000004419 157.0
HKD1_k127_6682277_8 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000000000000001305 142.0
HKD1_k127_6682277_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000008754 125.0
HKD1_k127_6684279_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 3.543e-248 778.0
HKD1_k127_6684279_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 3.305e-226 712.0
HKD1_k127_6684279_10 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.00000000000000000000000000000000004636 153.0
HKD1_k127_6684279_11 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000001097 148.0
HKD1_k127_6684279_12 Cytidylate kinase-like family - - - 0.000000000000000000000000003346 130.0
HKD1_k127_6684279_13 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000001147 113.0
HKD1_k127_6684279_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000003424 104.0
HKD1_k127_6684279_15 Protein of unknown function (DUF2892) - - - 0.000000000000000000001534 97.0
HKD1_k127_6684279_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 1.363e-212 671.0
HKD1_k127_6684279_3 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006067 347.0
HKD1_k127_6684279_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 366.0
HKD1_k127_6684279_5 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000009557 225.0
HKD1_k127_6684279_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000001628 234.0
HKD1_k127_6684279_7 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000758 215.0
HKD1_k127_6684279_8 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000002751 164.0
HKD1_k127_6684279_9 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000000001716 160.0
HKD1_k127_6716838_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 334.0
HKD1_k127_6716838_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001522 263.0
HKD1_k127_6726992_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 563.0
HKD1_k127_6726992_1 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 448.0
HKD1_k127_6726992_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000003404 190.0
HKD1_k127_6726992_3 TilS substrate binding domain K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000004085 196.0
HKD1_k127_6726992_4 Dolichyl-phosphate-mannose-protein mannosyltransferase K07264 - 2.4.2.43 0.000000000000000000000000000000000001736 157.0
HKD1_k127_6726992_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 0.0000000000000000000000000000000001434 151.0
HKD1_k127_6736094_0 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 0.0 1161.0
HKD1_k127_6736094_1 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 413.0
HKD1_k127_6736094_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004593 297.0
HKD1_k127_6745742_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 446.0
HKD1_k127_6745742_1 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 418.0
HKD1_k127_6745742_2 deaminase activity K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 427.0
HKD1_k127_6745742_3 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001731 240.0
HKD1_k127_6745742_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000003316 169.0
HKD1_k127_6745742_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000001559 152.0
HKD1_k127_6745742_6 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000003391 137.0
HKD1_k127_6745742_7 PBS lyase HEAT-like repeat - - - 0.00000001291 68.0
HKD1_k127_6764241_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000002694 201.0
HKD1_k127_6764241_1 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000001784 81.0
HKD1_k127_6804147_0 peptidyl-tyrosine sulfation - - - 1.887e-232 742.0
HKD1_k127_6804147_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 583.0
HKD1_k127_6804147_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 334.0
HKD1_k127_6804147_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000002286 232.0
HKD1_k127_6804147_4 YwiC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000001102 221.0
HKD1_k127_6804147_5 Protein of unknown function (DUF4019) - - - 0.00000000000000000000001391 106.0
HKD1_k127_6809725_0 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000002515 227.0
HKD1_k127_6809725_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000006798 147.0
HKD1_k127_6809725_2 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000115 105.0
HKD1_k127_6809725_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000008647 109.0
HKD1_k127_6817177_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102,K11103 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 559.0
HKD1_k127_6817177_1 L-lactate permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 492.0
HKD1_k127_6817177_2 Putative oxidoreductase C terminal domain - - - 0.00000000000000002335 83.0
HKD1_k127_6819415_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K03918,K07250,K13524 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 481.0
HKD1_k127_6819415_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 335.0
HKD1_k127_6819415_10 heat shock protein binding - - - 0.0000000000000001575 94.0
HKD1_k127_6819415_11 Response regulator, receiver - - - 0.0001422 55.0
HKD1_k127_6819415_2 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 313.0
HKD1_k127_6819415_3 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001523 284.0
HKD1_k127_6819415_4 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000131 271.0
HKD1_k127_6819415_5 belongs to the thioredoxin family K03671,K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.0000000000000000000000000000000000000001153 155.0
HKD1_k127_6819415_6 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000008411 127.0
HKD1_k127_6819415_7 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000003167 138.0
HKD1_k127_6819415_8 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000008468 117.0
HKD1_k127_6819415_9 cyclic nucleotide binding K04739,K10914 - - 0.00000000000000000005382 103.0
HKD1_k127_6820266_0 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 449.0
HKD1_k127_6820266_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 429.0
HKD1_k127_6820266_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002117 264.0
HKD1_k127_6854155_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.267e-257 816.0
HKD1_k127_6854155_1 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000001083 149.0
HKD1_k127_6854155_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000002337 131.0
HKD1_k127_6854155_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000005128 56.0
HKD1_k127_6855928_0 Amidohydrolase family - - - 6.407e-202 642.0
HKD1_k127_6855928_1 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 606.0
HKD1_k127_6855928_2 Oligopeptide transporter OPT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 552.0
HKD1_k127_6855928_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 449.0
HKD1_k127_6855928_4 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 427.0
HKD1_k127_6855928_5 Protein of unknown function (DUF2785) - - - 0.00000000000000000000000000000000000000000000002059 194.0
HKD1_k127_6855928_6 Elongation factor P K02356 - - 0.000000000000000000000000000000002607 138.0
HKD1_k127_6882262_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 455.0
HKD1_k127_6882262_1 Oligopeptide transporter OPT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002764 244.0
HKD1_k127_6882262_2 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000000000000000009474 187.0
HKD1_k127_6882262_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000121 175.0
HKD1_k127_6882262_4 PFAM phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000000001663 125.0
HKD1_k127_6882262_5 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.000000004873 57.0
HKD1_k127_6923760_0 Belongs to the mandelate racemase muconate lactonizing enzyme family K01706 - 4.2.1.40 4.462e-208 657.0
HKD1_k127_6923760_1 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 501.0
HKD1_k127_6923760_2 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002992 246.0
HKD1_k127_6923760_3 PAS fold - - - 0.00000000000003974 73.0
HKD1_k127_6948374_0 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 8.772e-198 628.0
HKD1_k127_6948374_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000004043 206.0
HKD1_k127_6948374_2 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000001525 165.0
HKD1_k127_6991543_0 Sodium:alanine symporter family K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 591.0
HKD1_k127_6991543_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 450.0
HKD1_k127_6991543_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000196 286.0
HKD1_k127_6991543_3 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003727 283.0
HKD1_k127_6991543_4 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000006724 237.0
HKD1_k127_6991543_5 PAS domain - - - 0.0000000000000000000000000000000000000000005638 182.0
HKD1_k127_6991543_6 Helix-turn-helix domain - - - 0.00000000000000000006075 103.0
HKD1_k127_7042258_0 transmembrane transporter activity K03296 - - 2.165e-238 786.0
HKD1_k127_7042258_1 Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose K16212 - 2.4.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 585.0
HKD1_k127_7042258_2 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 555.0
HKD1_k127_7042258_3 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 355.0
HKD1_k127_7042258_4 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000001151 193.0
HKD1_k127_7042258_5 COG1538 Outer membrane protein K15725 - - 0.00000000000000000000000000000002076 144.0
HKD1_k127_7042258_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000006553 136.0
HKD1_k127_7042258_7 Transcriptional regulatory protein, C terminal K07669,K07672 - - 0.00000000000001246 85.0
HKD1_k127_7044477_0 PFAM glycoside hydrolase family 39 K01198 - 3.2.1.37 4.677e-247 774.0
HKD1_k127_7044477_1 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 319.0
HKD1_k127_7044477_2 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.0000000000000000000000000000000000000000002085 167.0
HKD1_k127_7044477_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000005707 134.0
HKD1_k127_7044477_4 competence protein - - - 0.0000000000000000000000000005719 129.0
HKD1_k127_7044477_5 peptidase S9 K01278 - 3.4.14.5 0.0000000002012 72.0
HKD1_k127_7044477_6 Putative zinc-finger - - - 0.0002148 51.0
HKD1_k127_7062760_0 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 507.0
HKD1_k127_7062760_1 Vault protein inter-alpha-trypsin domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 415.0
HKD1_k127_7062760_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 375.0
HKD1_k127_7062760_3 HAMP domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 327.0
HKD1_k127_7062760_4 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000001149 228.0
HKD1_k127_7062760_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000988 175.0
HKD1_k127_7062760_6 Peptidase family M54 K06974 - - 0.000000000000000000000002048 120.0
HKD1_k127_7062760_7 diguanylate cyclase - - - 0.0000000009011 72.0
HKD1_k127_7062760_8 - - - - 0.0000000806 60.0
HKD1_k127_7062760_9 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.000001514 58.0
HKD1_k127_7086466_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 381.0
HKD1_k127_7086466_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000001097 99.0
HKD1_k127_7086466_2 PFAM Peptidase family M23 K08259 - 3.4.24.75 0.000000000267 62.0
HKD1_k127_7101625_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 519.0
HKD1_k127_7101625_1 Efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000004627 217.0
HKD1_k127_7101625_2 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000001529 73.0
HKD1_k127_7120347_0 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 348.0
HKD1_k127_7120347_1 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000005802 235.0
HKD1_k127_7120347_3 - - - - 0.00000000000006455 73.0
HKD1_k127_7142097_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 9.684e-222 699.0
HKD1_k127_7142097_1 General secretory system II, protein E domain protein K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 548.0
HKD1_k127_7142097_2 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884 426.0
HKD1_k127_7142097_3 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000009523 220.0
HKD1_k127_7142097_4 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000002976 190.0
HKD1_k127_7142097_5 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000001026 177.0
HKD1_k127_7149454_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000009919 153.0
HKD1_k127_7149454_1 S1 P1 Nuclease - - - 0.00000000000000000000000000001071 129.0
HKD1_k127_7149454_2 antisigma factor binding K04749,K06378 - - 0.000000008546 65.0
HKD1_k127_7149454_3 Protein of unknown function (DUF1573) - - - 0.00003516 54.0
HKD1_k127_7152892_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 558.0
HKD1_k127_7152892_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000001808 272.0
HKD1_k127_7152892_2 Trm112p-like protein K09791 - - 0.00000000000000000003596 90.0
HKD1_k127_7152892_3 O-antigen ligase like membrane protein - - - 0.0000000000000000007484 100.0
HKD1_k127_7164649_0 LytB protein K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 450.0
HKD1_k127_7164649_1 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 338.0
HKD1_k127_7164649_2 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 309.0
HKD1_k127_7164649_3 PFAM response regulator receiver K07657,K07664 - - 0.0000000000000000000000000000000000000004897 154.0
HKD1_k127_7167068_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 536.0
HKD1_k127_7167068_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 370.0
HKD1_k127_7167068_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 361.0
HKD1_k127_7167068_3 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 330.0
HKD1_k127_7167068_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 294.0
HKD1_k127_7167068_5 UDP-N-acetylenolpyruvoylglucosamine reductase K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000001464 201.0
HKD1_k127_7167068_6 Cell division protein FtsQ K03589 - - 0.0000000002213 74.0
HKD1_k127_7172721_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 329.0
HKD1_k127_7172721_1 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000001596 231.0
HKD1_k127_7184107_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 483.0
HKD1_k127_7184107_1 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000004453 261.0
HKD1_k127_7184107_2 COG4206 Outer membrane cobalamin receptor protein K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000006958 234.0
HKD1_k127_7184107_3 PDGLE domain K02007 - - 0.0000000000000000000000000000000000000000000000000000000000009412 226.0
HKD1_k127_7184107_4 Cobalt transport protein K02008 - - 0.000000000000000000000000003222 118.0
HKD1_k127_7184107_5 transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00004337 46.0
HKD1_k127_7206823_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000001908 152.0
HKD1_k127_7206823_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000175 94.0
HKD1_k127_7227111_0 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008757 583.0
HKD1_k127_7227111_1 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007746 537.0
HKD1_k127_7227111_2 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 425.0
HKD1_k127_7227111_3 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 408.0
HKD1_k127_7227111_4 - - - - 0.00000000000000000000000003999 118.0
HKD1_k127_7227111_5 protein secretion K03116 - - 0.000000000004151 68.0
HKD1_k127_7257851_0 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001839 267.0
HKD1_k127_7257851_1 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000003431 210.0
HKD1_k127_7257851_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000002588 181.0
HKD1_k127_7257851_3 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000000000109 123.0
HKD1_k127_7259500_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 539.0
HKD1_k127_7259500_1 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000006444 228.0
HKD1_k127_7259500_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000001336 239.0
HKD1_k127_7259500_3 - - - - 0.0000000000000000000000000000000003302 150.0
HKD1_k127_7259500_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000002904 111.0
HKD1_k127_7259500_6 - K14337 - - 0.000000000000000001179 102.0
HKD1_k127_7332750_0 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008373 537.0
HKD1_k127_7332750_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 425.0
HKD1_k127_7332750_2 DNA helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000008237 173.0
HKD1_k127_7332750_3 RF-1 domain K15034 - - 0.000000000000000000000000000000003 133.0
HKD1_k127_7332750_4 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000003801 113.0
HKD1_k127_7357372_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 7.846e-241 777.0
HKD1_k127_7357372_1 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 597.0
HKD1_k127_7357372_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 542.0
HKD1_k127_7410772_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 5.44e-321 1013.0
HKD1_k127_7410772_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.779e-209 659.0
HKD1_k127_7410772_10 GAF domain - - - 0.00000000000000003797 88.0
HKD1_k127_7410772_11 virulence factor MVIN family protein - - - 0.0000003871 63.0
HKD1_k127_7410772_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 300.0
HKD1_k127_7410772_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000003885 235.0
HKD1_k127_7410772_4 ATP:ADP antiporter activity K01932,K03301 - - 0.00000000000000000000000000000000000000000000000064 196.0
HKD1_k127_7410772_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000003297 149.0
HKD1_k127_7410772_6 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000001821 153.0
HKD1_k127_7410772_7 - - - - 0.0000000000000000000000000001687 121.0
HKD1_k127_7410772_8 B12 binding domain - - - 0.0000000000000000000000000125 126.0
HKD1_k127_7410772_9 Smr domain - - - 0.0000000000000000000001047 109.0
HKD1_k127_7435262_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000008258 241.0
HKD1_k127_7435262_1 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000001384 232.0
HKD1_k127_7435262_3 - - - - 0.0000000000000000000000000000001219 137.0
HKD1_k127_7435262_4 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000000000003135 127.0
HKD1_k127_7435262_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.00000000002982 71.0
HKD1_k127_7435262_7 (FHA) domain - - - 0.000000004097 66.0
HKD1_k127_7470237_0 Carbon starvation protein CstA K06200 - - 3.43e-277 869.0
HKD1_k127_7470237_1 PFAM homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 374.0
HKD1_k127_7470237_2 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 301.0
HKD1_k127_7470237_3 molybdate ABC transporter, inner membrane subunit K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007909 260.0
HKD1_k127_7470237_4 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000005104 211.0
HKD1_k127_7470237_5 FeS assembly SUF system protein SufT - - - 0.000000000000000000000000000000000000000000000000000004056 196.0
HKD1_k127_7470237_6 2 iron, 2 sulfur cluster binding - - - 0.00000000000000000000000000000000002478 147.0
HKD1_k127_7470237_7 NifU-like N terminal domain K04488 - - 0.0000000000000000000005473 96.0
HKD1_k127_7470237_8 cellulase activity - - - 0.00003638 56.0
HKD1_k127_7483688_0 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 426.0
HKD1_k127_7483688_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 306.0
HKD1_k127_7483688_2 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000009657 238.0
HKD1_k127_7483688_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000003327 216.0
HKD1_k127_7483688_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000004715 218.0
HKD1_k127_7483688_5 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000001274 124.0
HKD1_k127_7483688_6 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000004683 93.0
HKD1_k127_7483688_7 Forkhead associated domain - - - 0.000006052 60.0
HKD1_k127_7483688_8 PilZ domain - - - 0.00003749 53.0
HKD1_k127_7490799_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005716 405.0
HKD1_k127_7490799_1 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000003548 258.0
HKD1_k127_7490799_2 - - - - 0.000000000000000000000000000000000000000000000000001096 188.0
HKD1_k127_7490799_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000001704 113.0
HKD1_k127_7490799_4 Double zinc ribbon - - - 0.00006071 55.0
HKD1_k127_7491857_0 Malate/L-lactate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 408.0
HKD1_k127_7491857_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 357.0
HKD1_k127_7491857_2 - - - - 0.00000000000000000000000000000000000000000000000000005013 194.0
HKD1_k127_7491857_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000001469 186.0
HKD1_k127_7491857_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000008406 160.0
HKD1_k127_7491857_5 cytochrome complex assembly - - - 0.000000000000571 83.0
HKD1_k127_7491857_6 NADP oxidoreductase coenzyme F420-dependent - - - 0.0000001041 59.0
HKD1_k127_7493358_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1251.0
HKD1_k127_7493358_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 395.0
HKD1_k127_7493358_2 Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000003459 204.0
HKD1_k127_7493358_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000001483 162.0
HKD1_k127_7493358_4 Recombination factor protein RarA K07478 - - 0.000000000000000000002043 95.0
HKD1_k127_749615_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001246 240.0
HKD1_k127_749615_1 Putative ABC exporter - - - 0.0000000000000000000009291 110.0
HKD1_k127_7506899_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 510.0
HKD1_k127_7506899_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 408.0
HKD1_k127_7506899_10 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.00000000000000000000000000000000002188 150.0
HKD1_k127_7506899_2 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 383.0
HKD1_k127_7506899_3 Abhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 357.0
HKD1_k127_7506899_4 geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 326.0
HKD1_k127_7506899_5 periplasmic ligand-binding sensor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001368 296.0
HKD1_k127_7506899_6 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002719 267.0
HKD1_k127_7506899_7 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000001164 214.0
HKD1_k127_7506899_8 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000007392 215.0
HKD1_k127_7506899_9 dCMP deaminase activity K01493 - 3.5.4.12 0.000000000000000000000000000000000000000001906 164.0
HKD1_k127_7533426_0 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 539.0
HKD1_k127_7533426_1 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 531.0
HKD1_k127_7533426_2 TIGRFAM acetylornithine and succinylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 366.0
HKD1_k127_7533426_3 N-acetyl-gamma-glutamyl-phosphate reductase K00145 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0010035,GO:0010038,GO:0016020,GO:0031974,GO:0031981,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046686,GO:0046872,GO:0046914,GO:0050896,GO:0070013 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000004485 264.0
HKD1_k127_7533426_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000003667 222.0
HKD1_k127_7533426_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000005884 163.0
HKD1_k127_7537176_0 PFAM glycosyl transferase family 39 K14340 - - 0.0000000000000000000000000000000000000000000000000000000000000000002349 258.0
HKD1_k127_7537176_1 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000001218 159.0
HKD1_k127_7537176_2 actin binding - - - 0.00000000000000000000000000000000000000006421 154.0
HKD1_k127_7537176_3 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000006729 157.0
HKD1_k127_7537176_4 ECF sigma factor K03088 - - 0.0000000000000000009755 93.0
HKD1_k127_7537176_5 lipolytic protein G-D-S-L family - - - 0.000000004161 68.0
HKD1_k127_7537176_6 GDSL-like Lipase/Acylhydrolase family - - - 0.0002121 54.0
HKD1_k127_7540029_0 4 iron, 4 sulfur cluster binding K00184 - - 5.049e-307 968.0
HKD1_k127_7540029_1 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 565.0
HKD1_k127_7540029_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000002952 189.0
HKD1_k127_7548586_0 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 484.0
HKD1_k127_7548586_1 PAS domain containing protein K02030 - - 0.00000000000000000000000000000000000000000000000000000000000008914 221.0
HKD1_k127_7548586_2 response regulator - - - 0.00000000000000334 81.0
HKD1_k127_7556190_0 Glycogen debranching enzyme K05989 - 3.2.1.40 4.901e-275 861.0
HKD1_k127_7556190_1 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 493.0
HKD1_k127_7556190_2 Involved in the anomeric conversion of L-rhamnose K03534 - 5.1.3.32 0.00000000000000000000000000000000000000002966 154.0
HKD1_k127_7556190_3 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000006523 160.0
HKD1_k127_7556190_4 PFAM phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000000000000001996 141.0
HKD1_k127_7556190_5 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000002595 95.0
HKD1_k127_7556190_6 - - - - 0.00000000001362 70.0
HKD1_k127_7556190_7 Putative zinc-finger - - - 0.00001536 55.0
HKD1_k127_7572015_0 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 467.0
HKD1_k127_7572015_1 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 447.0
HKD1_k127_7572015_2 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 391.0
HKD1_k127_7572015_3 Sulfate ABC transporter inner membrane subunit CysT K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 362.0
HKD1_k127_7572015_4 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 321.0
HKD1_k127_7572015_5 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005318 280.0
HKD1_k127_7572015_7 Domain of unknown function (DUF4395) - - - 0.0000002003 59.0
HKD1_k127_7572015_8 Uncharacterized small protein (DUF2292) - - - 0.00001281 53.0
HKD1_k127_7573531_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 3.284e-230 722.0
HKD1_k127_7573531_1 Heat shock 70 kDa protein K04043 - - 2.671e-212 675.0
HKD1_k127_7573531_2 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 421.0
HKD1_k127_7573531_3 HrcA protein C terminal domain K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 302.0
HKD1_k127_7573531_4 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000008903 149.0
HKD1_k127_7573531_5 alpha beta alpha domain I K01840 - 5.4.2.8 0.00000000000000000000000000001871 118.0
HKD1_k127_7573531_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000001208 121.0
HKD1_k127_7573531_7 Polymer-forming cytoskeletal - - - 0.000000000000000000006809 100.0
HKD1_k127_7573531_8 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000002689 104.0
HKD1_k127_757564_0 Endonuclease exonuclease phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009918 256.0
HKD1_k127_757564_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008116 261.0
HKD1_k127_757564_2 phosphorelay signal transduction system K14987 - - 0.00000000000000000000000000000000000000000000001618 194.0
HKD1_k127_759900_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004716 287.0
HKD1_k127_759900_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000009401 195.0
HKD1_k127_759900_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000001775 130.0
HKD1_k127_759900_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000005064 128.0
HKD1_k127_759900_4 Tetratricopeptide repeats - - - 0.000000000000000000000000000007572 138.0
HKD1_k127_759900_5 Belongs to the UPF0109 family K06960 - - 0.000000008464 58.0
HKD1_k127_7649198_0 TrkA-C domain K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004003 275.0
HKD1_k127_7649198_1 TrkA-N domain K03499,K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000002619 235.0
HKD1_k127_7649198_2 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000006098 231.0
HKD1_k127_7652458_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000002781 155.0
HKD1_k127_7652458_2 Protein of unknown function (DUF2892) - - - 0.000000000000000001425 88.0
HKD1_k127_7652458_3 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.000000000000000004059 85.0
HKD1_k127_7652458_4 TIGRFAM TonB family K03832 - - 0.00000000000000678 88.0
HKD1_k127_7738209_0 ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 296.0
HKD1_k127_7738209_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001519 285.0
HKD1_k127_7738209_10 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000007698 164.0
HKD1_k127_7738209_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000004063 141.0
HKD1_k127_7738209_12 Polysaccharide deacetylase - - - 0.000000000000000000000008686 113.0
HKD1_k127_7738209_13 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000004986 113.0
HKD1_k127_7738209_14 PFAM O-antigen polymerase - - - 0.00000004582 66.0
HKD1_k127_7738209_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009047 254.0
HKD1_k127_7738209_3 bacterial-type flagellum-dependent cell motility K20951,K20952 - - 0.0000000000000000000000000000000000000000000000000000000000000000588 246.0
HKD1_k127_7738209_4 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000002404 240.0
HKD1_k127_7738209_5 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000004855 207.0
HKD1_k127_7738209_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000002495 216.0
HKD1_k127_7738209_7 deacetylase - - - 0.00000000000000000000000000000000000000000006546 174.0
HKD1_k127_7738209_8 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000009988 169.0
HKD1_k127_7738209_9 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000002395 168.0
HKD1_k127_7754220_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 449.0
HKD1_k127_7754220_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 400.0
HKD1_k127_7754220_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 347.0
HKD1_k127_7754220_3 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 308.0
HKD1_k127_7754220_4 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000000000000000000000001622 213.0
HKD1_k127_7754220_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000007372 71.0
HKD1_k127_7763855_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 307.0
HKD1_k127_7763855_1 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001794 288.0
HKD1_k127_7763855_2 Glycosyl hydrolase-like 10 - - - 0.00000000000000000000000000000000000000000000407 179.0
HKD1_k127_7778724_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 532.0
HKD1_k127_7790567_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 426.0
HKD1_k127_7790567_1 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008861 266.0
HKD1_k127_7790567_2 PFAM Peptidase S41 K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000256 220.0
HKD1_k127_7790567_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000492 202.0
HKD1_k127_7790567_4 YceG-like family K07082 - - 0.000000000000000000000000000000000000000133 168.0
HKD1_k127_7790567_5 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000003899 164.0
HKD1_k127_7790567_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000001312 129.0
HKD1_k127_7790567_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000001313 99.0
HKD1_k127_7790567_8 Peptidase M56 - - - 0.00005106 55.0
HKD1_k127_7796158_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 314.0
HKD1_k127_7796158_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000001906 250.0
HKD1_k127_7796158_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000002739 59.0
HKD1_k127_7827320_0 General secretory system II protein E domain protein - - - 5.469e-206 679.0
HKD1_k127_7827320_1 NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 568.0
HKD1_k127_7827320_10 - - - - 0.00000000000000000000007051 99.0
HKD1_k127_7827320_2 ATP-dependent helicase K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 567.0
HKD1_k127_7827320_3 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 516.0
HKD1_k127_7827320_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 469.0
HKD1_k127_7827320_5 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001642 287.0
HKD1_k127_7827320_6 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008547 287.0
HKD1_k127_7827320_7 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000004289 203.0
HKD1_k127_7827320_8 tRNA methyltransferase complex GCD14 subunit - - - 0.00000000000000000000000000000000000000000001227 184.0
HKD1_k127_7827320_9 membrane - - - 0.0000000000000000000000000000000004104 142.0
HKD1_k127_7850010_0 purine nucleobase transmembrane transporter activity K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 547.0
HKD1_k127_7850010_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 454.0
HKD1_k127_7850010_2 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 389.0
HKD1_k127_7850010_3 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 401.0
HKD1_k127_7850010_4 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001412 271.0
HKD1_k127_7850010_5 COG0474 Cation transport ATPase K01535,K12955 - 3.6.3.6 0.0000000000000000000000000000000000000000000000000000000000000000001439 238.0
HKD1_k127_7850010_6 metallopeptidase activity K15531,K19668,K20276 - 3.2.1.156,3.2.1.91 0.00001663 51.0
HKD1_k127_7877554_0 PFAM ABC transporter transmembrane K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 377.0
HKD1_k127_7877554_1 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 307.0
HKD1_k127_7881432_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 535.0
HKD1_k127_7881432_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 439.0
HKD1_k127_7881432_2 glycerophosphodiester transmembrane transport K02026,K08715 - - 0.00000000000008889 72.0
HKD1_k127_7892741_0 RNA binding S1 domain protein K06959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 614.0
HKD1_k127_7892741_1 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 559.0
HKD1_k127_7892741_2 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000003303 165.0
HKD1_k127_7892741_3 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000002 113.0
HKD1_k127_7901391_0 Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 415.0
HKD1_k127_7901391_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000006152 164.0
HKD1_k127_7901391_2 Acid phosphatase - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000001089 132.0
HKD1_k127_7925497_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004676 282.0
HKD1_k127_7925497_1 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002733 261.0
HKD1_k127_7925497_10 Belongs to the UPF0235 family K09131 - - 0.00000000002368 72.0
HKD1_k127_7925497_11 Amidohydrolase family K01468 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.2.7 0.000004811 54.0
HKD1_k127_7925497_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000007076 255.0
HKD1_k127_7925497_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000006725 218.0
HKD1_k127_7925497_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000001064 214.0
HKD1_k127_7925497_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000007315 99.0
HKD1_k127_7925497_6 DivIVA protein K04074 - - 0.00000000000000000007288 95.0
HKD1_k127_7925497_7 peptidyl-tyrosine sulfation - - - 0.000000000000000001747 96.0
HKD1_k127_7925497_8 YGGT family K02221 - - 0.00000000000000001918 85.0
HKD1_k127_7925497_9 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000005787 82.0
HKD1_k127_7978659_0 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 437.0
HKD1_k127_7978659_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002118 280.0
HKD1_k127_7978659_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000001069 229.0
HKD1_k127_7978659_3 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000002938 196.0
HKD1_k127_7978659_4 Glycoside hydrolase - - - 0.000000000000000000000000000000000000000005404 168.0
HKD1_k127_7978659_5 - - - - 0.000000000000000000000000000000000416 147.0
HKD1_k127_7978659_6 - - - - 0.000000000000000000000000000007149 127.0
HKD1_k127_798518_0 Glucuronate isomerase K01812 - 5.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 550.0
HKD1_k127_798518_1 PFAM Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 477.0
HKD1_k127_798518_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 351.0
HKD1_k127_798518_3 FCD K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000001237 238.0
HKD1_k127_798518_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000002381 165.0
HKD1_k127_7988124_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 1.328e-261 820.0
HKD1_k127_7988124_1 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 429.0
HKD1_k127_7989171_0 Glycosyl transferases group 1 K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 401.0
HKD1_k127_7989171_1 Bacillithiol biosynthesis BshC K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000003538 236.0
HKD1_k127_7989171_2 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000002693 185.0
HKD1_k127_7989758_0 Phosphopantetheine attachment site - - - 5.017e-241 783.0
HKD1_k127_7989758_1 regulation of translation K03530 - - 0.000000000000000000000002993 104.0
HKD1_k127_7989758_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000001006 76.0
HKD1_k127_7998757_0 Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 483.0
HKD1_k127_7998757_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 306.0
HKD1_k127_7998757_2 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 305.0
HKD1_k127_7998757_3 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000377 218.0
HKD1_k127_7998757_4 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000006285 125.0
HKD1_k127_7998757_5 oxidative phosphorylation K00426 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.0001134 46.0
HKD1_k127_838505_0 Transporter associated domain K03699,K06189 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 398.0
HKD1_k127_838505_1 Type ii and iii secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000001495 196.0
HKD1_k127_838505_2 Belongs to the GSP D family K02453 - - 0.0000000000000000000000000000035 136.0
HKD1_k127_838505_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000003456 107.0
HKD1_k127_83964_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 407.0
HKD1_k127_83964_1 Phenazine biosynthesis-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 323.0
HKD1_k127_83964_2 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009382 278.0
HKD1_k127_83964_3 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001236 283.0
HKD1_k127_83964_4 Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000002266 246.0
HKD1_k127_83964_5 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000003041 235.0
HKD1_k127_83964_6 Thioredoxin K03671 - - 0.00000000000000000000000000000000002953 141.0
HKD1_k127_83964_7 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07478 - - 0.000000000000000000000002234 117.0
HKD1_k127_83964_8 - - - - 0.00005352 53.0
HKD1_k127_852416_0 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 312.0
HKD1_k127_852416_1 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000008183 242.0
HKD1_k127_852416_3 PAS domain containing protein K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000001934 240.0
HKD1_k127_870234_0 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 557.0
HKD1_k127_870234_1 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 536.0
HKD1_k127_870234_2 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 436.0
HKD1_k127_870234_3 COGs COG2912 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000006245 239.0
HKD1_k127_870234_4 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000002349 208.0
HKD1_k127_870234_5 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000001273 167.0
HKD1_k127_870234_6 NAD(P)+ transhydrogenase (AB-specific) activity K00324 - 1.6.1.2 0.0000000000000000000001124 105.0
HKD1_k127_870234_7 guanyl-nucleotide exchange factor activity - - - 0.0000006265 62.0
HKD1_k127_886556_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 346.0
HKD1_k127_886556_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 333.0
HKD1_k127_886556_2 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000002015 199.0
HKD1_k127_886556_3 LamB/YcsF family K07160 - - 0.0001728 53.0
HKD1_k127_892624_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 403.0
HKD1_k127_892624_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639,K20967 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0030312,GO:0040007,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0071944,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22,4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 346.0
HKD1_k127_892624_10 Oxygen tolerance - - - 0.000000000000000000000000000000000000005707 166.0
HKD1_k127_892624_11 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000000002264 149.0
HKD1_k127_892624_12 NUDIX domain - - - 0.00000000000000000000000000000004286 140.0
HKD1_k127_892624_14 Shikimate O-hydroxycinnamoyltransferase-like K13065 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0008150,GO:0008152,GO:0008374,GO:0009058,GO:0009698,GO:0009699,GO:0009808,GO:0009809,GO:0009889,GO:0009891,GO:0009893,GO:0009962,GO:0009963,GO:0009987,GO:0010252,GO:0016020,GO:0016740,GO:0016746,GO:0016747,GO:0019222,GO:0019438,GO:0019748,GO:0042592,GO:0044237,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0047172,GO:0047205,GO:0048518,GO:0048878,GO:0050734,GO:0050737,GO:0050789,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:1901360,GO:1901362,GO:1901576 2.3.1.133 0.0000000000002076 82.0
HKD1_k127_892624_15 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.0000000000002219 75.0
HKD1_k127_892624_16 - - - - 0.0000000000007009 79.0
HKD1_k127_892624_17 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.0000000008223 70.0
HKD1_k127_892624_19 Transcriptional regulator, Fis family - - - 0.00007738 50.0
HKD1_k127_892624_2 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 349.0
HKD1_k127_892624_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 316.0
HKD1_k127_892624_4 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 292.0
HKD1_k127_892624_5 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000276 251.0
HKD1_k127_892624_6 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000008959 254.0
HKD1_k127_892624_7 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000001636 249.0
HKD1_k127_892624_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000002459 211.0
HKD1_k127_892624_9 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000008417 188.0
HKD1_k127_894384_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.737e-283 891.0
HKD1_k127_894384_1 hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 512.0
HKD1_k127_894384_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 376.0
HKD1_k127_894384_3 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 353.0
HKD1_k127_894384_4 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000000000000000001194 209.0
HKD1_k127_894384_5 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.00000000000000000000000000000000007078 141.0
HKD1_k127_894384_6 HupF/HypC family K04653 - - 0.000000000000000000000000001979 114.0
HKD1_k127_894384_7 High-affinity Fe2 Pb2 permease K07243 - - 0.000000000000002082 83.0
HKD1_k127_894384_8 HupF/HypC family K04653 - - 0.0005848 53.0
HKD1_k127_903414_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 332.0
HKD1_k127_903414_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007345 286.0
HKD1_k127_915444_0 Hydrolase CocE NonD family - - - 3.697e-313 971.0
HKD1_k127_915444_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.19e-270 873.0
HKD1_k127_915444_10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000009368 264.0
HKD1_k127_915444_11 ATP:ADP antiporter activity K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001114 278.0
HKD1_k127_915444_12 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000005332 195.0
HKD1_k127_915444_13 PFAM pyruvate phosphate dikinase PEP pyruvate-binding protein - - - 0.0000000000000000000000000000000000000000000005356 184.0
HKD1_k127_915444_14 PFAM Hemerythrin HHE cation binding domain protein - - - 0.000000000000000000000000000000000000002574 154.0
HKD1_k127_915444_15 Copper binding proteins, plastocyanin/azurin family - - - 0.00000001281 66.0
HKD1_k127_915444_16 PFAM EamA-like transporter family - - - 0.0002778 52.0
HKD1_k127_915444_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.063e-226 710.0
HKD1_k127_915444_3 Alpha-L-fucosidase C-terminal domain K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 608.0
HKD1_k127_915444_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 559.0
HKD1_k127_915444_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 510.0
HKD1_k127_915444_6 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 507.0
HKD1_k127_915444_7 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 460.0
HKD1_k127_915444_8 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 353.0
HKD1_k127_915444_9 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 373.0
HKD1_k127_935848_0 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000221 263.0
HKD1_k127_935848_1 Virulence factor BrkB K07058 - - 0.000000000000000127 89.0
HKD1_k127_935848_2 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.0000000161 61.0
HKD1_k127_952668_0 ABC transporter, transmembrane K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 587.0
HKD1_k127_952668_1 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 461.0
HKD1_k127_952668_10 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000619 60.0
HKD1_k127_952668_2 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 440.0
HKD1_k127_952668_3 N-acyl-L-amino acid amidohydrolase K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 401.0
HKD1_k127_952668_4 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 404.0
HKD1_k127_952668_5 S4 RNA-binding domain K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.00000000000000000000000000000000000000000000000000004177 203.0
HKD1_k127_952668_6 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000005009 151.0
HKD1_k127_952668_7 Belongs to the ompA family - - - 0.000000000000000000000000000000001069 148.0
HKD1_k127_952668_8 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000006465 131.0
HKD1_k127_952668_9 von Willebrand factor, type A K12511 - - 0.0000000000000000001073 100.0
HKD1_k127_964304_0 Serine carboxypeptidase - - - 5.823e-234 738.0
HKD1_k127_964304_1 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 556.0
HKD1_k127_964304_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 458.0
HKD1_k127_964304_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000004336 237.0
HKD1_k127_964304_4 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000007997 121.0
HKD1_k127_964304_5 - - - - 0.00005608 56.0