Overview

ID MAG01706
Name HKD1_bin.18
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA6898
Genus JAKAGF01
Species
Assembly information
Completeness (%) 85.2
Contamination (%) 2.55
GC content (%) 57.0
N50 (bp) 16,289
Genome size (bp) 2,736,296

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2536

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1005796_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.082e-269 849.0
HKD1_k127_1005796_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 1.042e-248 789.0
HKD1_k127_1005796_10 Transcriptional regulator, MerR family - - - 0.0000000000000000000000000000000005595 135.0
HKD1_k127_1005796_11 BON domain - - - 0.00000000000000000000002101 109.0
HKD1_k127_1005796_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000001362 88.0
HKD1_k127_1005796_14 Cupin 2, conserved barrel domain protein - - - 0.00000000001418 70.0
HKD1_k127_1005796_15 PAS fold - - - 0.00000001818 68.0
HKD1_k127_1005796_16 YVTN family beta-propeller repeat - - - 0.0000002853 55.0
HKD1_k127_1005796_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 6.899e-195 629.0
HKD1_k127_1005796_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.911e-194 613.0
HKD1_k127_1005796_4 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 321.0
HKD1_k127_1005796_5 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 307.0
HKD1_k127_1005796_6 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 293.0
HKD1_k127_1005796_7 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000007608 223.0
HKD1_k127_1005796_8 mRNA catabolic process - - - 0.0000000000000000000000000000000000000000000000000000005715 202.0
HKD1_k127_1005796_9 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000006029 140.0
HKD1_k127_1080927_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 3.247e-290 897.0
HKD1_k127_1080927_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.309e-207 651.0
HKD1_k127_1080927_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 550.0
HKD1_k127_1080927_3 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 391.0
HKD1_k127_1080927_4 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 371.0
HKD1_k127_1080927_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.000000000000000000000000000000000000000000000000002546 187.0
HKD1_k127_1080927_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000008915 94.0
HKD1_k127_1085096_0 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 384.0
HKD1_k127_1085096_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 389.0
HKD1_k127_1085096_2 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 325.0
HKD1_k127_1085096_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 328.0
HKD1_k127_1085096_4 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000001602 147.0
HKD1_k127_1085096_6 GatB Yqey domain protein K09117 - - 0.00001661 47.0
HKD1_k127_1088801_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 588.0
HKD1_k127_1088801_1 (ABC) transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 436.0
HKD1_k127_1088801_10 PFAM ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000008805 176.0
HKD1_k127_1088801_11 - - - - 0.00000000000269 69.0
HKD1_k127_1088801_12 - - - - 0.00000007365 56.0
HKD1_k127_1088801_2 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 435.0
HKD1_k127_1088801_3 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 409.0
HKD1_k127_1088801_4 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 408.0
HKD1_k127_1088801_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 303.0
HKD1_k127_1088801_6 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007205 288.0
HKD1_k127_1088801_7 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002163 274.0
HKD1_k127_1088801_8 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000002417 220.0
HKD1_k127_1088801_9 Protein of unknown function (DUF3455) - - - 0.000000000000000000000000000000000000000000000000000000000000036 219.0
HKD1_k127_111973_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.351e-252 784.0
HKD1_k127_111973_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.608e-241 753.0
HKD1_k127_111973_10 HD domain - - - 0.0000000000000000000000000000000000000000000000008409 189.0
HKD1_k127_111973_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000001469 156.0
HKD1_k127_111973_12 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000000002452 158.0
HKD1_k127_111973_13 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000008517 147.0
HKD1_k127_111973_14 Protein required for attachment to host cells - - - 0.000000000000000000000000000000000001093 143.0
HKD1_k127_111973_15 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000002575 141.0
HKD1_k127_111973_16 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000000000000004045 124.0
HKD1_k127_111973_18 Ftsk_gamma K03466 - - 0.0000000000000000003534 87.0
HKD1_k127_111973_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.597e-234 749.0
HKD1_k127_111973_20 antisigma factor binding K04749 - - 0.000000000000005406 80.0
HKD1_k127_111973_21 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000001014 84.0
HKD1_k127_111973_22 helix_turn_helix, Lux Regulon - - - 0.0000000000004929 73.0
HKD1_k127_111973_23 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00001708 52.0
HKD1_k127_111973_24 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0007747 43.0
HKD1_k127_111973_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.418e-222 706.0
HKD1_k127_111973_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 469.0
HKD1_k127_111973_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 400.0
HKD1_k127_111973_6 response regulator receiver K02481,K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 394.0
HKD1_k127_111973_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 319.0
HKD1_k127_111973_8 Protein of unknown function (DUF4239) - - - 0.000000000000000000000000000000000000000000000000000000000000000009154 233.0
HKD1_k127_111973_9 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000001519 209.0
HKD1_k127_1239626_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 559.0
HKD1_k127_1239626_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 463.0
HKD1_k127_1239626_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 417.0
HKD1_k127_1239626_3 pfam abc K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 374.0
HKD1_k127_1239626_4 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 305.0
HKD1_k127_1239626_5 cytochrome - - - 0.0000000000000000000000005476 106.0
HKD1_k127_1340626_0 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 410.0
HKD1_k127_1340626_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 415.0
HKD1_k127_1340626_2 S-methyl-5'-thioadenosine phosphorylase K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004645,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0010033,GO:0016053,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017061,GO:0017144,GO:0019221,GO:0019509,GO:0019752,GO:0023052,GO:0032259,GO:0034097,GO:0034641,GO:0035722,GO:0042221,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070671,GO:0070887,GO:0071265,GO:0071267,GO:0071310,GO:0071345,GO:0071349,GO:0071704,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 321.0
HKD1_k127_1340626_3 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 306.0
HKD1_k127_1340626_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000963 278.0
HKD1_k127_1340626_5 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000006602 223.0
HKD1_k127_1340626_6 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000002015 173.0
HKD1_k127_1340626_7 YtxH-like protein - - - 0.000000000000000000000000000009136 121.0
HKD1_k127_1340626_8 nickel cation binding K04651,K19640 - - 0.00000000000000000000000000007331 121.0
HKD1_k127_1340626_9 Tetratricopeptide repeat - - - 0.0000000000009992 77.0
HKD1_k127_1366526_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 514.0
HKD1_k127_1366526_1 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 510.0
HKD1_k127_1366526_2 Membrane bound O-acyl transferase MBOAT family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 457.0
HKD1_k127_1366526_3 Competence protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 375.0
HKD1_k127_1366526_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 327.0
HKD1_k127_1366526_5 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000006557 241.0
HKD1_k127_1366526_6 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000005092 200.0
HKD1_k127_1366526_7 - - - - 0.000000000000000000000000000000000000000000000004429 188.0
HKD1_k127_1366526_8 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.0000000000000000000000000000000000000002308 160.0
HKD1_k127_1366526_9 YbbR-like protein - - - 0.0000000000000000000000000000000000000004444 162.0
HKD1_k127_1383157_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1020.0
HKD1_k127_1383157_1 metal cluster binding K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 321.0
HKD1_k127_1383157_2 GAF domain - - - 0.00000000000000000000000000000000004303 141.0
HKD1_k127_1383157_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.000000000000000000001827 96.0
HKD1_k127_1383157_6 phosphorelay sensor kinase activity - - - 0.00000002461 63.0
HKD1_k127_1403145_0 PFAM major facilitator superfamily MFS_1 K02575 - - 2.131e-242 756.0
HKD1_k127_1403145_1 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein K11181 GO:0003674,GO:0003824,GO:0005575,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016002,GO:0016020,GO:0016491,GO:0016667,GO:0016673,GO:0019419,GO:0044237,GO:0050311,GO:0055114 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 330.0
HKD1_k127_1403145_2 TIGRFAM respiratory nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 285.0
HKD1_k127_1403145_3 PFAM nitrite and sulphite reductase 4Fe-4S K11180 GO:0005575,GO:0016020 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001967 282.0
HKD1_k127_1403145_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003503 222.0
HKD1_k127_1403145_5 TIGRFAM nitrate reductase molybdenum cofactor assembly chaperone K00373 - - 0.0000000000000000000000000000000001271 139.0
HKD1_k127_1403145_6 sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.000000000000000000005875 96.0
HKD1_k127_1403145_7 Hemerythrin HHE cation binding domain - - - 0.000000009335 58.0
HKD1_k127_1462026_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 1.754e-281 886.0
HKD1_k127_1462026_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 4.069e-209 662.0
HKD1_k127_1462026_10 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000006174 118.0
HKD1_k127_1462026_11 Belongs to the universal stress protein A family - - - 0.0000000000000000000001516 103.0
HKD1_k127_1462026_13 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000003845 56.0
HKD1_k127_1462026_14 Bacterial protein of unknown function (DUF922) - - - 0.0006958 50.0
HKD1_k127_1462026_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 581.0
HKD1_k127_1462026_3 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 479.0
HKD1_k127_1462026_4 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 434.0
HKD1_k127_1462026_5 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 335.0
HKD1_k127_1462026_6 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 331.0
HKD1_k127_1462026_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 332.0
HKD1_k127_1462026_8 PFAM peptidase M28 - - - 0.0000000000000000000000000000000000000001543 157.0
HKD1_k127_1462026_9 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000000001882 138.0
HKD1_k127_1494118_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 507.0
HKD1_k127_1494118_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 488.0
HKD1_k127_1494118_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 473.0
HKD1_k127_1494118_3 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 431.0
HKD1_k127_1494118_4 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000000000000000000002418 217.0
HKD1_k127_1542244_0 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 0.0 1262.0
HKD1_k127_1542244_1 His Kinase A (phospho-acceptor) domain - - - 0.0 1020.0
HKD1_k127_1542244_10 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 365.0
HKD1_k127_1542244_11 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 354.0
HKD1_k127_1542244_12 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 304.0
HKD1_k127_1542244_13 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002025 277.0
HKD1_k127_1542244_14 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002355 275.0
HKD1_k127_1542244_15 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001649 244.0
HKD1_k127_1542244_16 denitrification pathway K02569,K15876 - - 0.00000000000000000000000000000000000000000000000006907 190.0
HKD1_k127_1542244_17 Arginine-tRNA-protein transferase, N terminus K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000001274 173.0
HKD1_k127_1542244_18 response regulator receiver - - - 0.0000000000000000000000000000000000000000101 156.0
HKD1_k127_1542244_19 Protein of unknown function (DUF3617) - - - 0.00000000000000000000000000000000001642 140.0
HKD1_k127_1542244_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2e-323 1004.0
HKD1_k127_1542244_20 Cysteine-rich small domain - - - 0.0000000000000000005264 89.0
HKD1_k127_1542244_21 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000004278 58.0
HKD1_k127_1542244_22 - - - - 0.0000000548 59.0
HKD1_k127_1542244_23 SNARE associated Golgi protein - - - 0.00004633 46.0
HKD1_k127_1542244_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 541.0
HKD1_k127_1542244_4 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 526.0
HKD1_k127_1542244_5 DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 523.0
HKD1_k127_1542244_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 475.0
HKD1_k127_1542244_7 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 473.0
HKD1_k127_1542244_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 446.0
HKD1_k127_1542244_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 421.0
HKD1_k127_1567189_0 Glycosyl transferase family 21 - - - 7.899e-224 701.0
HKD1_k127_1567189_1 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000001146 225.0
HKD1_k127_1567189_3 - - - - 0.000000000000000006175 96.0
HKD1_k127_1567189_4 Tetratricopeptide repeat - - - 0.0000000000009361 75.0
HKD1_k127_1567189_5 PFAM amino acid-binding ACT domain protein - - - 0.000001007 57.0
HKD1_k127_1643243_0 GTP-binding protein TypA K06207 - - 1.321e-267 835.0
HKD1_k127_1643243_1 NADH-quinone oxidoreductase K00341 - 1.6.5.3 1.902e-240 758.0
HKD1_k127_1643243_10 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000007325 149.0
HKD1_k127_1643243_11 - - - - 0.0000000000000000000000000000003065 137.0
HKD1_k127_1643243_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000001137 123.0
HKD1_k127_1643243_13 von Willebrand factor (vWF) type A domain - - - 0.0001475 44.0
HKD1_k127_1643243_14 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0003186 50.0
HKD1_k127_1643243_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 3.105e-195 621.0
HKD1_k127_1643243_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 553.0
HKD1_k127_1643243_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 446.0
HKD1_k127_1643243_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 406.0
HKD1_k127_1643243_6 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 365.0
HKD1_k127_1643243_7 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 288.0
HKD1_k127_1643243_8 Amidohydrolase family - - - 0.000000000000000000000000000000000000000001913 168.0
HKD1_k127_1643243_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000004709 150.0
HKD1_k127_175889_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 520.0
HKD1_k127_175889_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 428.0
HKD1_k127_175889_10 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000005841 155.0
HKD1_k127_175889_11 Domain of unknown function (DUF1992) - - - 0.00000000000000000000000000000000000002265 147.0
HKD1_k127_175889_12 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000007185 127.0
HKD1_k127_175889_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 319.0
HKD1_k127_175889_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005863 276.0
HKD1_k127_175889_5 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000004045 244.0
HKD1_k127_175889_6 PFAM periplasmic solute binding protein K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000211 247.0
HKD1_k127_175889_7 ABC-type Mn2 Zn2 transport system, permease component K09816,K09819,K19976 - - 0.00000000000000000000000000000000000000000000000000000001259 209.0
HKD1_k127_175889_8 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000002294 199.0
HKD1_k127_175889_9 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000003679 195.0
HKD1_k127_1799160_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 4.978e-247 792.0
HKD1_k127_1799160_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.102e-228 722.0
HKD1_k127_1799160_10 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000006986 226.0
HKD1_k127_1799160_11 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000174 149.0
HKD1_k127_1799160_12 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000002122 116.0
HKD1_k127_1799160_13 nucleotidyltransferase activity K07075 - - 0.0000000000000000000000000003021 121.0
HKD1_k127_1799160_14 - - - - 0.00000000000000000000002146 104.0
HKD1_k127_1799160_15 Domain of unknown function (DUF1858) - - - 0.00000000000000000004297 91.0
HKD1_k127_1799160_16 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000004695 67.0
HKD1_k127_1799160_17 4Fe-4S binding domain - - - 0.00000002203 57.0
HKD1_k127_1799160_18 Aspartyl protease - - - 0.000003026 57.0
HKD1_k127_1799160_19 protein trimerization K07114 - - 0.00004278 53.0
HKD1_k127_1799160_2 Peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 537.0
HKD1_k127_1799160_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 553.0
HKD1_k127_1799160_4 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 509.0
HKD1_k127_1799160_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 433.0
HKD1_k127_1799160_6 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 381.0
HKD1_k127_1799160_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009797 304.0
HKD1_k127_1799160_8 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000007911 265.0
HKD1_k127_1799160_9 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000001895 223.0
HKD1_k127_1818540_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1857.0
HKD1_k127_1818540_1 - K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 427.0
HKD1_k127_1818540_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003494 286.0
HKD1_k127_1818540_3 response regulator K02667 - - 0.00000000000000000000000000006484 121.0
HKD1_k127_1818540_4 protein conserved in bacteria - - - 0.00000000000000000000008579 102.0
HKD1_k127_1818540_5 - - - - 0.0000000000000000007642 90.0
HKD1_k127_1818540_6 AsmA-like C-terminal region K07289 - - 0.00000000003153 76.0
HKD1_k127_1869875_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 487.0
HKD1_k127_1869875_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 404.0
HKD1_k127_1869875_2 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 398.0
HKD1_k127_1869875_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 364.0
HKD1_k127_1869875_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 319.0
HKD1_k127_1869875_5 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000002033 192.0
HKD1_k127_1869875_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000000001259 173.0
HKD1_k127_1869875_7 CAAX protease self-immunity - - - 0.000000005393 64.0
HKD1_k127_1869875_8 Fibronectin type III domain - - - 0.00000008422 65.0
HKD1_k127_1892772_0 chelatase, subunit ChlI K07391 - - 1.806e-205 650.0
HKD1_k127_1892772_1 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 471.0
HKD1_k127_1892772_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000004432 228.0
HKD1_k127_1892772_11 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000007044 220.0
HKD1_k127_1892772_12 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000000000000000000002897 195.0
HKD1_k127_1892772_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000006275 156.0
HKD1_k127_1892772_14 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000005625 136.0
HKD1_k127_1892772_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000142 121.0
HKD1_k127_1892772_17 Regulatory protein, FmdB family - - - 0.0000000000000000002001 89.0
HKD1_k127_1892772_2 cysteine synthase K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 452.0
HKD1_k127_1892772_3 COG0555 ABC-type sulfate transport system, permease component K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 388.0
HKD1_k127_1892772_4 TIGRFAM sulfate ABC transporter, permease protein CysW, sulfate ABC transporter, permease protein K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 387.0
HKD1_k127_1892772_5 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 360.0
HKD1_k127_1892772_6 Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 357.0
HKD1_k127_1892772_7 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 310.0
HKD1_k127_1892772_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 289.0
HKD1_k127_1892772_9 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.0000000000000000000000000000000000000000000000000000000000000001017 228.0
HKD1_k127_1921741_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 1.06e-281 887.0
HKD1_k127_1921741_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 603.0
HKD1_k127_1921741_10 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000005968 170.0
HKD1_k127_1921741_11 - - - - 0.0000000000000000000000000000000000000002408 158.0
HKD1_k127_1921741_12 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000000001393 134.0
HKD1_k127_1921741_13 - - - - 0.0000000000000000000000000009785 116.0
HKD1_k127_1921741_14 PFAM RNA recognition motif - - - 0.00000000000000000000001385 103.0
HKD1_k127_1921741_15 FixH - - - 0.00000000000000004951 84.0
HKD1_k127_1921741_16 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.000000000000004712 79.0
HKD1_k127_1921741_2 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 325.0
HKD1_k127_1921741_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001914 266.0
HKD1_k127_1921741_4 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004559 241.0
HKD1_k127_1921741_5 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000002178 234.0
HKD1_k127_1921741_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000003202 204.0
HKD1_k127_1921741_7 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000008135 205.0
HKD1_k127_1921741_8 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000003043 189.0
HKD1_k127_1921741_9 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000243 182.0
HKD1_k127_1960260_0 E1-E2 ATPase K17686 - 3.6.3.54 6.506e-314 977.0
HKD1_k127_1960260_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 417.0
HKD1_k127_1960260_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000001267 135.0
HKD1_k127_1960260_3 YtkA-like - - - 0.000000000002857 72.0
HKD1_k127_1978506_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 521.0
HKD1_k127_1978506_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 474.0
HKD1_k127_1978506_10 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0002429 45.0
HKD1_k127_1978506_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 392.0
HKD1_k127_1978506_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 295.0
HKD1_k127_1978506_4 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000001339 229.0
HKD1_k127_1978506_5 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000000000000000001714 211.0
HKD1_k127_1978506_6 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000000000000000000000004554 211.0
HKD1_k127_1978506_7 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.00000000000000000000000000000000000000000000001683 174.0
HKD1_k127_1978506_8 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000007229 128.0
HKD1_k127_1978506_9 Protein of unknown function (DUF559) - - - 0.00003106 49.0
HKD1_k127_2011811_0 PFAM V-type ATPase 116 kDa K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009157 556.0
HKD1_k127_2011811_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 528.0
HKD1_k127_2011811_10 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000001869 222.0
HKD1_k127_2011811_11 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000000000000000000000000001702 216.0
HKD1_k127_2011811_13 PAS fold - - - 0.0000000000000000000000002581 113.0
HKD1_k127_2011811_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000001007 101.0
HKD1_k127_2011811_15 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000000000001779 98.0
HKD1_k127_2011811_16 EamA-like transporter family - - - 0.00000000000000000003432 101.0
HKD1_k127_2011811_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000009098 91.0
HKD1_k127_2011811_18 Protein of unknown function (DUF2892) - - - 0.000000000038 70.0
HKD1_k127_2011811_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 496.0
HKD1_k127_2011811_3 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 467.0
HKD1_k127_2011811_4 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 460.0
HKD1_k127_2011811_5 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 385.0
HKD1_k127_2011811_6 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005313 273.0
HKD1_k127_2011811_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002894 266.0
HKD1_k127_2011811_8 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000569 273.0
HKD1_k127_2011811_9 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001537 244.0
HKD1_k127_2075110_0 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13017 - 1.17.1.1,2.6.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 499.0
HKD1_k127_2075110_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 445.0
HKD1_k127_2075110_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 319.0
HKD1_k127_2075110_11 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 309.0
HKD1_k127_2075110_12 glycosyl transferase K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000618 280.0
HKD1_k127_2075110_13 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002199 270.0
HKD1_k127_2075110_14 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000141 267.0
HKD1_k127_2075110_15 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004281 276.0
HKD1_k127_2075110_16 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001744 256.0
HKD1_k127_2075110_17 Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002996 252.0
HKD1_k127_2075110_18 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002983 232.0
HKD1_k127_2075110_19 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000001029 236.0
HKD1_k127_2075110_2 carbamoylphosphate synthase large subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 444.0
HKD1_k127_2075110_20 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.00000000000000000000000000000000000000000000000000000000003744 207.0
HKD1_k127_2075110_21 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000001024 211.0
HKD1_k127_2075110_22 Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000001102 216.0
HKD1_k127_2075110_23 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000001746 197.0
HKD1_k127_2075110_24 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000002101 208.0
HKD1_k127_2075110_25 Hypothetical methyltransferase - - - 0.0000000000000000000000000000000000000000000000002061 187.0
HKD1_k127_2075110_26 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000003833 164.0
HKD1_k127_2075110_27 HlyD family secretion protein K01993,K02005 - - 0.00000000000000000000000000009967 128.0
HKD1_k127_2075110_28 Sulfotransferase domain - - - 0.000000000000000000000000001177 123.0
HKD1_k127_2075110_29 acetyltransferase - - - 0.0000000000000000000000003441 114.0
HKD1_k127_2075110_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 434.0
HKD1_k127_2075110_30 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0003443 53.0
HKD1_k127_2075110_4 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 430.0
HKD1_k127_2075110_5 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 424.0
HKD1_k127_2075110_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 411.0
HKD1_k127_2075110_7 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 408.0
HKD1_k127_2075110_8 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 391.0
HKD1_k127_2075110_9 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 329.0
HKD1_k127_2096717_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 4.697e-209 659.0
HKD1_k127_2096717_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 484.0
HKD1_k127_2096717_10 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000006561 145.0
HKD1_k127_2096717_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000004378 136.0
HKD1_k127_2096717_12 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000001056 132.0
HKD1_k127_2096717_13 phosphorelay signal transduction system - - - 0.000000000000000000000000004947 114.0
HKD1_k127_2096717_14 gag-polyprotein putative aspartyl protease - - - 0.00000000000000000000000002025 118.0
HKD1_k127_2096717_15 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000005317 97.0
HKD1_k127_2096717_16 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000000000000000005508 91.0
HKD1_k127_2096717_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 418.0
HKD1_k127_2096717_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 390.0
HKD1_k127_2096717_4 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 400.0
HKD1_k127_2096717_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 398.0
HKD1_k127_2096717_6 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 364.0
HKD1_k127_2096717_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 307.0
HKD1_k127_2096717_8 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005687 276.0
HKD1_k127_2096717_9 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000003295 169.0
HKD1_k127_2096825_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 2.979e-290 902.0
HKD1_k127_2096825_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 1.435e-243 760.0
HKD1_k127_2096825_10 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000006904 224.0
HKD1_k127_2096825_11 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003212 224.0
HKD1_k127_2096825_12 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000002047 182.0
HKD1_k127_2096825_13 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000002259 194.0
HKD1_k127_2096825_14 PFAM Pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000003624 164.0
HKD1_k127_2096825_15 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000004722 136.0
HKD1_k127_2096825_16 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.00000000000000000000000000000001802 127.0
HKD1_k127_2096825_17 phosphorelay signal transduction system - - - 0.00000000000000000000000000006171 124.0
HKD1_k127_2096825_18 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000008447 106.0
HKD1_k127_2096825_19 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.000000000000000000002093 93.0
HKD1_k127_2096825_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 488.0
HKD1_k127_2096825_20 carbon dioxide binding K04653 - - 0.000000000000000001135 88.0
HKD1_k127_2096825_21 Protein of unknown function (DUF1189) - - - 0.000000000000003077 88.0
HKD1_k127_2096825_22 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000001502 73.0
HKD1_k127_2096825_23 LemA family K03744 - - 0.000003599 53.0
HKD1_k127_2096825_3 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 448.0
HKD1_k127_2096825_4 formate dehydrogenase, beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 383.0
HKD1_k127_2096825_5 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 344.0
HKD1_k127_2096825_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 286.0
HKD1_k127_2096825_7 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003324 273.0
HKD1_k127_2096825_8 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001199 251.0
HKD1_k127_2096825_9 histidine kinase, HAMP K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000003055 244.0
HKD1_k127_2122076_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 5.733e-269 856.0
HKD1_k127_2122076_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.088e-266 836.0
HKD1_k127_2122076_10 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000116 213.0
HKD1_k127_2122076_11 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000001251 204.0
HKD1_k127_2122076_13 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000002966 146.0
HKD1_k127_2122076_14 Cold shock K03704 - - 0.0000000000000000000000001737 108.0
HKD1_k127_2122076_15 part of a sulfur-relay system K11179 - - 0.00000000000000000000002968 101.0
HKD1_k127_2122076_16 Predicted RNA-binding protein - - - 0.0000000000000000001237 91.0
HKD1_k127_2122076_17 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000005549 77.0
HKD1_k127_2122076_18 response regulator, receiver K01338 - 3.4.21.53 0.0000000000103 69.0
HKD1_k127_2122076_2 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 548.0
HKD1_k127_2122076_3 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 473.0
HKD1_k127_2122076_4 Cytochrome C and Quinol oxidase polypeptide I K04561 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0055114 1.7.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 409.0
HKD1_k127_2122076_5 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 361.0
HKD1_k127_2122076_6 PFAM Cytochrome b5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 301.0
HKD1_k127_2122076_7 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001203 287.0
HKD1_k127_2122076_8 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001214 289.0
HKD1_k127_2122076_9 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000003777 235.0
HKD1_k127_2129357_0 Squalene-hopene cyclase C-terminal domain K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 1.503e-228 729.0
HKD1_k127_2129357_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 565.0
HKD1_k127_2129357_10 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001787 263.0
HKD1_k127_2129357_11 Adenylylsulphate kinase K00860 - 2.7.1.25 0.0000000000000000000000000000000000000008314 154.0
HKD1_k127_2129357_12 hopanoid biosynthesis associated protein HpnK K03478 - 3.5.1.105 0.000000000000000000000000000000000000003946 159.0
HKD1_k127_2129357_13 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000005362 139.0
HKD1_k127_2129357_14 EamA-like transporter family - - - 0.000000000000000001033 93.0
HKD1_k127_2129357_15 Copper resistance protein D K07245 - - 0.00000000001044 67.0
HKD1_k127_2129357_16 Phosphorylase superfamily K01243 - 3.2.2.9 0.00000006498 63.0
HKD1_k127_2129357_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 397.0
HKD1_k127_2129357_3 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 405.0
HKD1_k127_2129357_4 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 388.0
HKD1_k127_2129357_5 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 385.0
HKD1_k127_2129357_6 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 352.0
HKD1_k127_2129357_7 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 304.0
HKD1_k127_2129357_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003304 277.0
HKD1_k127_2129357_9 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000002539 273.0
HKD1_k127_2130242_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.724e-196 622.0
HKD1_k127_2130242_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 468.0
HKD1_k127_2130242_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 454.0
HKD1_k127_2130242_3 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000003935 217.0
HKD1_k127_2130242_4 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 0.000000000000000000000000000000001146 132.0
HKD1_k127_2136958_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1568.0
HKD1_k127_2136958_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K05587,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 1.543e-260 815.0
HKD1_k127_2136958_10 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 292.0
HKD1_k127_2136958_11 zinc ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002015 270.0
HKD1_k127_2136958_12 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000598 251.0
HKD1_k127_2136958_13 PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004711 249.0
HKD1_k127_2136958_14 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000153 236.0
HKD1_k127_2136958_15 PHP-associated K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000002079 231.0
HKD1_k127_2136958_16 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.000000000000000000000000000000000000000000000000000000000003209 214.0
HKD1_k127_2136958_17 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000003688 205.0
HKD1_k127_2136958_18 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000001837 191.0
HKD1_k127_2136958_19 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000379 188.0
HKD1_k127_2136958_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.051e-257 812.0
HKD1_k127_2136958_20 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K18330 - 1.12.1.3 0.000000000000000000000000000000000000000000001971 177.0
HKD1_k127_2136958_21 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000007654 158.0
HKD1_k127_2136958_22 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000001547 151.0
HKD1_k127_2136958_23 MgtC family K07507 - - 0.00000000000000000000000000000000000004092 151.0
HKD1_k127_2136958_24 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000000000000000005561 140.0
HKD1_k127_2136958_25 GAF domain - - - 0.0000000000000000000000000000000003571 147.0
HKD1_k127_2136958_26 DRTGG domain - - - 0.0000000000000000000000000000008391 126.0
HKD1_k127_2136958_27 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000104 124.0
HKD1_k127_2136958_28 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000004383 117.0
HKD1_k127_2136958_29 PFAM DRTGG domain - - - 0.000000000000000000000000008859 114.0
HKD1_k127_2136958_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.571e-206 661.0
HKD1_k127_2136958_30 phosphorelay sensor kinase activity - - - 0.000000000000000001419 99.0
HKD1_k127_2136958_31 Sigma-54 dependent response regulator K07714 - - 0.00000000000001744 81.0
HKD1_k127_2136958_32 oligosaccharyl transferase activity - - - 0.00000000496 60.0
HKD1_k127_2136958_33 Prokaryotic N-terminal methylation motif K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0000004615 59.0
HKD1_k127_2136958_35 Tetratricopeptide repeat protein - - - 0.0008696 50.0
HKD1_k127_2136958_4 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 557.0
HKD1_k127_2136958_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 564.0
HKD1_k127_2136958_6 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 496.0
HKD1_k127_2136958_7 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 370.0
HKD1_k127_2136958_8 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 373.0
HKD1_k127_2136958_9 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 337.0
HKD1_k127_215937_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.677e-231 734.0
HKD1_k127_2257591_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K12955 - 3.6.3.6 0.0 1282.0
HKD1_k127_2257591_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.101e-299 927.0
HKD1_k127_2257591_10 Pfam Response regulator receiver K02488 - 2.7.7.65 0.0000000000000000000000000000000000000001579 153.0
HKD1_k127_2257591_11 diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000004637 145.0
HKD1_k127_2257591_12 cheY-homologous receiver domain - - - 0.0000000000000000000000000000008314 129.0
HKD1_k127_2257591_13 - - - - 0.0000000000002072 74.0
HKD1_k127_2257591_14 Domains HisKA, HATPase_c - - - 0.0000000000009776 70.0
HKD1_k127_2257591_2 ABC transporter K06158 - - 4.974e-235 743.0
HKD1_k127_2257591_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 484.0
HKD1_k127_2257591_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 401.0
HKD1_k127_2257591_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 394.0
HKD1_k127_2257591_6 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000007908 254.0
HKD1_k127_2257591_7 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005483 259.0
HKD1_k127_2257591_8 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000005159 248.0
HKD1_k127_2257591_9 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000001116 200.0
HKD1_k127_2263906_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 574.0
HKD1_k127_2263906_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 370.0
HKD1_k127_2263906_2 HAF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 341.0
HKD1_k127_2263906_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000223 186.0
HKD1_k127_2263906_4 Domain of unknown function (DUF4124) K08309 - - 0.000000000000000000000000000000000000000001837 164.0
HKD1_k127_2263906_5 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843,K02849 - - 0.00000000000000000000000000002511 130.0
HKD1_k127_2263906_6 fibronectin type III domain protein - - - 0.00000000000000001239 97.0
HKD1_k127_2263906_7 Cytochrome c K08906,K12263 - - 0.0000000000002927 74.0
HKD1_k127_2263906_8 - - - - 0.00000001262 56.0
HKD1_k127_2263906_9 fibronectin type III domain protein - - - 0.0000355 46.0
HKD1_k127_2331577_0 Glycosyltransferase WbsX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 529.0
HKD1_k127_2331577_1 CAAX prenyl protease N-terminal, five membrane helices - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 429.0
HKD1_k127_2331577_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 421.0
HKD1_k127_2331577_3 sugar transferase K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 395.0
HKD1_k127_2331577_4 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003078 278.0
HKD1_k127_2331577_5 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000008589 224.0
HKD1_k127_2331577_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000008669 151.0
HKD1_k127_2340947_0 Peptidase family M28 - - - 0.0 1042.0
HKD1_k127_2340947_1 SMART Elongator protein 3 MiaB NifB - - - 2.736e-219 689.0
HKD1_k127_2340947_10 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000007787 197.0
HKD1_k127_2340947_11 DoxX K15977 - - 0.000000000000000000000000000000000000000000007284 167.0
HKD1_k127_2340947_12 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000005254 156.0
HKD1_k127_2340947_13 PFAM Carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000002937 139.0
HKD1_k127_2340947_14 GYD domain - - - 0.0000000000000000000000000000000002057 134.0
HKD1_k127_2340947_15 FRG - - - 0.000000000000000000000000000000004619 139.0
HKD1_k127_2340947_16 sulfur carrier activity K04085 - - 0.0000000000000000000000005302 106.0
HKD1_k127_2340947_17 - - - - 0.00000000000000000000001444 101.0
HKD1_k127_2340947_18 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000002162 101.0
HKD1_k127_2340947_19 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000002886 80.0
HKD1_k127_2340947_2 Beta Propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 546.0
HKD1_k127_2340947_20 Universal stress protein family - - - 0.00000000002586 73.0
HKD1_k127_2340947_21 - - - - 0.00000000004981 67.0
HKD1_k127_2340947_22 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000006656 65.0
HKD1_k127_2340947_23 - - - - 0.0000005564 55.0
HKD1_k127_2340947_25 - - - - 0.00003071 57.0
HKD1_k127_2340947_26 - - - - 0.0001945 46.0
HKD1_k127_2340947_3 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 488.0
HKD1_k127_2340947_4 Sulphur transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 429.0
HKD1_k127_2340947_5 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 426.0
HKD1_k127_2340947_6 Amine oxidase, flavin-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 354.0
HKD1_k127_2340947_8 PFAM glycosyl transferase, family 9 K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 332.0
HKD1_k127_2340947_9 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000008499 203.0
HKD1_k127_2467526_0 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 488.0
HKD1_k127_2467526_1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002153 266.0
HKD1_k127_2484450_0 AcrB/AcrD/AcrF family K03296,K19594 - - 0.0 1581.0
HKD1_k127_2484450_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.009e-272 850.0
HKD1_k127_2484450_10 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000002707 205.0
HKD1_k127_2484450_11 TraB family K09973 - - 0.000000000000000000000000000000000000000000000000003247 193.0
HKD1_k127_2484450_12 NosL - - - 0.000000000000000000000000000000000000000006654 160.0
HKD1_k127_2484450_13 translation release factor activity - - - 0.00000000000000000000000000000000000000001728 156.0
HKD1_k127_2484450_14 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000003538 120.0
HKD1_k127_2484450_15 Helix-turn-helix domain protein - - - 0.000000000000000003667 90.0
HKD1_k127_2484450_16 - - - - 0.0000000002838 66.0
HKD1_k127_2484450_17 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000002657 69.0
HKD1_k127_2484450_18 SEC-C motif - - - 0.000000006787 58.0
HKD1_k127_2484450_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 5.766e-217 684.0
HKD1_k127_2484450_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 574.0
HKD1_k127_2484450_4 Biotin-lipoyl like K19595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 447.0
HKD1_k127_2484450_5 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 417.0
HKD1_k127_2484450_6 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 294.0
HKD1_k127_2484450_7 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002329 283.0
HKD1_k127_2484450_8 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001572 276.0
HKD1_k127_2484450_9 PFAM HhH-GPD superfamily base excision DNA repair protein K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005809 249.0
HKD1_k127_252599_0 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 482.0
HKD1_k127_252599_1 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 358.0
HKD1_k127_252599_2 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 331.0
HKD1_k127_252599_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000001276 207.0
HKD1_k127_252599_4 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000000000000000004626 190.0
HKD1_k127_252599_5 General secretion pathway protein H K02457 - - 0.00001802 53.0
HKD1_k127_2566678_0 amino acid K14052 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008324,GO:0008519,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015101,GO:0015203,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015489,GO:0015672,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0033554,GO:0034220,GO:0034641,GO:0040011,GO:0042402,GO:0044106,GO:0044237,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051234,GO:0051674,GO:0051716,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072488,GO:0097164,GO:0098655,GO:0098660,GO:0098662,GO:1901564,GO:1901565,GO:1901575,GO:1902047,GO:1902600 - 2.174e-277 866.0
HKD1_k127_2566678_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.901e-272 844.0
HKD1_k127_2566678_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 535.0
HKD1_k127_2566678_3 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006811 246.0
HKD1_k127_2566678_4 Serine/threonine phosphatases, family 2C, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000004076 223.0
HKD1_k127_2566678_5 - - - - 0.00000000000000000000000000000000000000000000000007477 187.0
HKD1_k127_2566678_6 - - - - 0.00000000000000000000000000000000003875 143.0
HKD1_k127_2566678_7 PFAM thiamineS protein - - - 0.00000000003515 69.0
HKD1_k127_2566678_8 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000004586 59.0
HKD1_k127_2605072_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 452.0
HKD1_k127_2605072_1 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 319.0
HKD1_k127_2605072_2 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 285.0
HKD1_k127_2605072_3 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003597 277.0
HKD1_k127_2605072_4 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000002803 182.0
HKD1_k127_2605072_5 Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000004273 174.0
HKD1_k127_2605072_6 PFAM PHP domain - - - 0.000000000000000000000000000000000000004427 155.0
HKD1_k127_2605072_7 Protein of unknown function (DUF1698) - - - 0.0000000000000000000000000000002668 134.0
HKD1_k127_2605072_8 Protein-disulfide isomerase - - - 0.0000000000000000000000000000005868 126.0
HKD1_k127_2605072_9 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000001129 57.0
HKD1_k127_2609195_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 6.439e-260 816.0
HKD1_k127_2609195_1 Belongs to the thiolase family K00626 - 2.3.1.9 2.532e-227 709.0
HKD1_k127_2609195_10 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001758 277.0
HKD1_k127_2609195_11 FAD binding domain K10960,K21401 - 1.3.1.111,1.3.1.83,1.3.99.38 0.000000000000000000000000000000000000000003755 168.0
HKD1_k127_2609195_12 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000006391 151.0
HKD1_k127_2609195_13 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000298 108.0
HKD1_k127_2609195_14 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000001112 98.0
HKD1_k127_2609195_15 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000001557 60.0
HKD1_k127_2609195_16 Membrane - - - 0.000007373 57.0
HKD1_k127_2609195_17 Putative regulatory protein - - - 0.00001516 49.0
HKD1_k127_2609195_2 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 1.392e-218 690.0
HKD1_k127_2609195_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 608.0
HKD1_k127_2609195_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 591.0
HKD1_k127_2609195_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 512.0
HKD1_k127_2609195_6 histidine kinase A domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 512.0
HKD1_k127_2609195_7 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 494.0
HKD1_k127_2609195_8 COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 451.0
HKD1_k127_2609195_9 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 300.0
HKD1_k127_27347_0 Sigma-54 interaction domain - - - 2.212e-230 727.0
HKD1_k127_27347_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 341.0
HKD1_k127_27347_2 General secretory system II, protein E domain protein K02454 - - 0.000000000000000000000000000001864 125.0
HKD1_k127_27347_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000003748 104.0
HKD1_k127_2738160_0 AsmA-like C-terminal region - - - 4.769e-204 678.0
HKD1_k127_2738160_1 beta-glucosidase activity K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 598.0
HKD1_k127_2738160_10 - - - - 0.0000000000000006574 85.0
HKD1_k127_2738160_2 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 478.0
HKD1_k127_2738160_3 Signal transduction histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 341.0
HKD1_k127_2738160_4 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000441 287.0
HKD1_k127_2738160_5 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004174 278.0
HKD1_k127_2738160_6 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000000002989 164.0
HKD1_k127_2738160_7 Belongs to the ompA family K03286 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000001136 119.0
HKD1_k127_2738160_8 PFAM PRC-barrel domain - - - 0.0000000000000000000000000003838 119.0
HKD1_k127_2738160_9 Short repeat of unknown function (DUF308) - - - 0.00000000000000000002871 102.0
HKD1_k127_2808731_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1576.0
HKD1_k127_2808731_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 522.0
HKD1_k127_2808731_2 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 445.0
HKD1_k127_2808731_3 HMGL-like K01666 - 4.1.3.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 410.0
HKD1_k127_2808731_4 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000004147 183.0
HKD1_k127_2808731_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000003897 149.0
HKD1_k127_2808731_7 - - - - 0.000000214 55.0
HKD1_k127_2808731_8 - - - - 0.0000008115 52.0
HKD1_k127_2812751_0 Chain length determinant protein K16554 - - 3.084e-197 638.0
HKD1_k127_2812751_1 Lipid A core-O-antigen ligase-like enyme K18814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 537.0
HKD1_k127_2812751_2 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.00000000000000000000000001703 112.0
HKD1_k127_2812751_3 export protein K01991 - - 0.00000000000000000007511 89.0
HKD1_k127_2812751_5 PFAM Tetratricopeptide repeat - - - 0.0000009492 62.0
HKD1_k127_2827548_0 4Fe-4S dicluster domain - - - 3.321e-312 960.0
HKD1_k127_2827548_1 Seven times multi-haem cytochrome CxxCH - - - 2.37e-197 625.0
HKD1_k127_2827548_10 - - - - 0.00000000000000000000000000000000000000000005564 164.0
HKD1_k127_2827548_11 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.00000000000000000000000000000000000000006707 152.0
HKD1_k127_2827548_12 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000004524 133.0
HKD1_k127_2827548_13 lyase activity - - - 0.0000000000000000001435 93.0
HKD1_k127_2827548_14 4Fe-4S binding domain - - - 0.000000000000000005171 85.0
HKD1_k127_2827548_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 565.0
HKD1_k127_2827548_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 528.0
HKD1_k127_2827548_4 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 432.0
HKD1_k127_2827548_5 4 iron, 4 sulfur cluster binding K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 334.0
HKD1_k127_2827548_6 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 314.0
HKD1_k127_2827548_7 Histidine kinase K07642,K18143 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001671 273.0
HKD1_k127_2827548_8 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000000000000000000000001785 189.0
HKD1_k127_2827548_9 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000000000000000000000000004142 169.0
HKD1_k127_2851_0 radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 384.0
HKD1_k127_2851_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 394.0
HKD1_k127_2851_2 AMMECR1 K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 331.0
HKD1_k127_2851_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000006332 233.0
HKD1_k127_2851_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000005331 143.0
HKD1_k127_2881496_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 2.269e-246 773.0
HKD1_k127_2881496_1 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22341 - 1.17.1.11,1.17.1.9 5.858e-203 644.0
HKD1_k127_2881496_2 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 485.0
HKD1_k127_2881496_3 phosphorelay signal transduction system K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 482.0
HKD1_k127_2881496_4 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 360.0
HKD1_k127_2881496_5 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 334.0
HKD1_k127_2881496_6 Mo-molybdopterin cofactor metabolic process K02379 - - 0.00000000000000000000000000000000000000000000000000000000003197 214.0
HKD1_k127_2881496_7 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000001207 192.0
HKD1_k127_2881496_8 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000003531 134.0
HKD1_k127_2909384_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 355.0
HKD1_k127_2909384_1 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 342.0
HKD1_k127_2909384_2 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001237 300.0
HKD1_k127_2909384_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000001677 245.0
HKD1_k127_2909384_4 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000001311 242.0
HKD1_k127_2909384_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000164 113.0
HKD1_k127_2909384_6 PFAM Pilus assembly protein PilO K02664 - - 0.00000000000003623 80.0
HKD1_k127_2909384_7 Pilus assembly protein, PilP K02665 - - 0.00000000000013 77.0
HKD1_k127_2909384_8 Fimbrial assembly protein (PilN) K02663 - - 0.0000000001121 70.0
HKD1_k127_2933570_0 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 490.0
HKD1_k127_2933570_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 375.0
HKD1_k127_2933570_2 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 364.0
HKD1_k127_2933570_3 Putative Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 339.0
HKD1_k127_2933570_4 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000008386 235.0
HKD1_k127_2933570_5 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000002255 212.0
HKD1_k127_2933570_6 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000001925 128.0
HKD1_k127_2933570_7 binding domain protein - - - 0.00000000000002188 75.0
HKD1_k127_2937737_0 Phosphoglucan, water dikinase K15535 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019200,GO:0019538,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044275,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046777,GO:0046835,GO:0051752,GO:0071704,GO:1901564,GO:1901575 2.7.9.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 590.0
HKD1_k127_2937737_1 Alpha amylase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 533.0
HKD1_k127_2937737_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K08244 - 2.7.9.4 0.00000000000000000000000000000000000000000000001597 175.0
HKD1_k127_2937737_3 Nitroreductase family - - - 0.000000000000000000000000000000009484 136.0
HKD1_k127_2937737_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000005357 126.0
HKD1_k127_2937737_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000004425 74.0
HKD1_k127_2937737_6 Xylose isomerase-like TIM barrel - - - 0.000008918 60.0
HKD1_k127_2941586_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 6.09e-267 833.0
HKD1_k127_2941586_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 2.244e-202 640.0
HKD1_k127_2941586_2 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 408.0
HKD1_k127_2941586_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009883 241.0
HKD1_k127_2941586_4 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000001 202.0
HKD1_k127_2941586_5 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000005416 155.0
HKD1_k127_2941586_6 LysM domain - - - 0.0000000000000000000000000000000002524 150.0
HKD1_k127_2944762_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1026.0
HKD1_k127_2944762_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 348.0
HKD1_k127_2944762_11 Protein of unknown function (DUF1573) - - - 0.00007865 48.0
HKD1_k127_2944762_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000003511 246.0
HKD1_k127_2944762_3 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000009645 242.0
HKD1_k127_2944762_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000007023 183.0
HKD1_k127_2944762_5 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000000000000000001529 133.0
HKD1_k127_2944762_6 rubredoxin - - - 0.0000000000000000000003225 100.0
HKD1_k127_2944762_7 Major facilitator Superfamily - - - 0.000000000000000001524 87.0
HKD1_k127_2944762_8 NusG domain II K00805 - 2.5.1.30 0.000000000000002322 80.0
HKD1_k127_2944762_9 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000995 78.0
HKD1_k127_2972929_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 7.608e-318 989.0
HKD1_k127_2972929_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.286e-301 943.0
HKD1_k127_2972929_10 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 419.0
HKD1_k127_2972929_11 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 400.0
HKD1_k127_2972929_12 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 396.0
HKD1_k127_2972929_13 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 394.0
HKD1_k127_2972929_14 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 343.0
HKD1_k127_2972929_15 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 336.0
HKD1_k127_2972929_16 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 329.0
HKD1_k127_2972929_17 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 325.0
HKD1_k127_2972929_18 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 316.0
HKD1_k127_2972929_19 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 294.0
HKD1_k127_2972929_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.446e-216 675.0
HKD1_k127_2972929_20 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000001126 236.0
HKD1_k127_2972929_21 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000007353 234.0
HKD1_k127_2972929_22 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000001834 216.0
HKD1_k127_2972929_23 2Fe-2S -binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000004753 215.0
HKD1_k127_2972929_24 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000022 184.0
HKD1_k127_2972929_25 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000002577 165.0
HKD1_k127_2972929_26 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000008896 168.0
HKD1_k127_2972929_27 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000003514 148.0
HKD1_k127_2972929_29 NTPase - - - 0.00000000000000000000000000003027 124.0
HKD1_k127_2972929_3 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 1.343e-213 671.0
HKD1_k127_2972929_30 PFAM thioesterase superfamily - - - 0.000000000000000000000000001316 116.0
HKD1_k127_2972929_31 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000002831 110.0
HKD1_k127_2972929_32 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000003651 106.0
HKD1_k127_2972929_33 - - - - 0.0000000000000000004196 94.0
HKD1_k127_2972929_34 Uncharacterised protein family (UPF0158) - - - 0.000000000267 69.0
HKD1_k127_2972929_37 Tetratricopeptide repeat - - - 0.0008932 52.0
HKD1_k127_2972929_4 Elongation factor SelB, winged helix K03833 - - 3.592e-211 674.0
HKD1_k127_2972929_5 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 519.0
HKD1_k127_2972929_6 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008185 519.0
HKD1_k127_2972929_7 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 458.0
HKD1_k127_2972929_8 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 443.0
HKD1_k127_2972929_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 412.0
HKD1_k127_3019559_0 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 395.0
HKD1_k127_3019559_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 314.0
HKD1_k127_3019559_2 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000001906 259.0
HKD1_k127_3019559_3 - - - - 0.000000000000000000000000000000000000000000000000000000357 199.0
HKD1_k127_3019559_4 - - - - 0.0000000000000008412 79.0
HKD1_k127_3024009_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1502.0
HKD1_k127_3024009_1 Alpha-glucan water dikinase K08244 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009266,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009605,GO:0009607,GO:0009608,GO:0009610,GO:0009620,GO:0009628,GO:0009631,GO:0009941,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0031967,GO:0031975,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0050521,GO:0050896,GO:0051704,GO:0051707,GO:0071704,GO:1901575 2.7.9.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 500.0
HKD1_k127_3024009_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 398.0
HKD1_k127_3024009_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 361.0
HKD1_k127_3024009_4 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 324.0
HKD1_k127_3024009_5 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.000000000000000000000000000000000000000000000139 172.0
HKD1_k127_3024009_6 YtkA-like - - - 0.00000000000000842 79.0
HKD1_k127_311412_0 Sugar (and other) transporter K03446 - - 1.759e-226 711.0
HKD1_k127_311412_1 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 4.708e-215 691.0
HKD1_k127_311412_10 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 314.0
HKD1_k127_311412_11 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003929 279.0
HKD1_k127_311412_12 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000003876 289.0
HKD1_k127_311412_13 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003064 276.0
HKD1_k127_311412_14 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005459 254.0
HKD1_k127_311412_15 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000002164 227.0
HKD1_k127_311412_16 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000002218 226.0
HKD1_k127_311412_17 Maf-like protein K06287 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - 0.000000000000000000000000000000000000000000000005241 179.0
HKD1_k127_311412_18 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000002128 129.0
HKD1_k127_311412_19 metalloendopeptidase activity - - - 0.000000000000000000000007682 113.0
HKD1_k127_311412_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 597.0
HKD1_k127_311412_20 exonuclease activity K16899 - 3.6.4.12 0.00000000000000001492 98.0
HKD1_k127_311412_21 - - - - 0.00000000003865 68.0
HKD1_k127_311412_22 Cytochrome c554 and c-prime - - - 0.000002126 54.0
HKD1_k127_311412_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 464.0
HKD1_k127_311412_4 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 460.0
HKD1_k127_311412_5 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 439.0
HKD1_k127_311412_6 HlyD membrane-fusion protein of T1SS K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 406.0
HKD1_k127_311412_7 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 379.0
HKD1_k127_311412_8 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 344.0
HKD1_k127_311412_9 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 330.0
HKD1_k127_3149230_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 301.0
HKD1_k127_3149230_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009262 273.0
HKD1_k127_3149230_2 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000006038 187.0
HKD1_k127_3149230_3 DJ-1/PfpI family K03152,K05520,K05687 - 3.5.1.124 0.000000000000000000000000000000000000000000000006794 174.0
HKD1_k127_3149230_4 Belongs to the glycosyl hydrolase 3 family K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000013 180.0
HKD1_k127_3149230_5 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000006639 144.0
HKD1_k127_3149230_6 heat shock protein binding - - - 0.000000000139 74.0
HKD1_k127_3149230_7 Transposase - - - 0.00000006116 60.0
HKD1_k127_3149701_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1043.0
HKD1_k127_3149701_1 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1035.0
HKD1_k127_3149701_2 Sigma-54 interaction domain - - - 2.772e-199 634.0
HKD1_k127_3149701_3 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 416.0
HKD1_k127_3149701_4 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000001158 236.0
HKD1_k127_3152024_0 TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 580.0
HKD1_k127_3152024_1 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000001233 242.0
HKD1_k127_3152024_2 PFAM toluene tolerance K07323 - - 0.000000000000000000000000000000000000001954 154.0
HKD1_k127_3152024_3 bacterial OsmY and nodulation domain K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.0000009244 56.0
HKD1_k127_3156776_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 451.0
HKD1_k127_3156776_1 cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000002402 169.0
HKD1_k127_3156776_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000005119 57.0
HKD1_k127_3205400_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 336.0
HKD1_k127_3205400_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003003 244.0
HKD1_k127_3205400_2 Phosphate acyltransferases K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000879 241.0
HKD1_k127_3205400_3 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000001789 172.0
HKD1_k127_3217220_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.475e-277 866.0
HKD1_k127_3217220_1 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 453.0
HKD1_k127_3217220_2 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000019 256.0
HKD1_k127_3217220_3 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006485 248.0
HKD1_k127_3217220_4 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000002074 219.0
HKD1_k127_3217220_5 PFAM Tetratricopeptide repeat - - - 0.000006434 55.0
HKD1_k127_3233141_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 7.042e-283 897.0
HKD1_k127_3233141_1 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 1.162e-259 819.0
HKD1_k127_3233141_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 427.0
HKD1_k127_3233141_11 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 422.0
HKD1_k127_3233141_12 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 384.0
HKD1_k127_3233141_13 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 376.0
HKD1_k127_3233141_14 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 383.0
HKD1_k127_3233141_15 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 362.0
HKD1_k127_3233141_16 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 355.0
HKD1_k127_3233141_17 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 353.0
HKD1_k127_3233141_18 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 316.0
HKD1_k127_3233141_19 His Kinase A (phosphoacceptor) domain K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001752 268.0
HKD1_k127_3233141_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 7.471e-257 805.0
HKD1_k127_3233141_20 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002792 256.0
HKD1_k127_3233141_21 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003403 253.0
HKD1_k127_3233141_22 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000001374 255.0
HKD1_k127_3233141_23 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000006849 232.0
HKD1_k127_3233141_24 electron transfer activity K02305,K08738 - - 0.000000000000000000000000000000000000000000000000000004352 195.0
HKD1_k127_3233141_25 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000006321 187.0
HKD1_k127_3233141_26 PFAM Cache, type 2 - - - 0.0000000000000000000000000000000000000000000000001538 181.0
HKD1_k127_3233141_27 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000002903 179.0
HKD1_k127_3233141_28 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000001921 176.0
HKD1_k127_3233141_29 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.000000000000000000000000000000000000000000000002928 178.0
HKD1_k127_3233141_3 Glycosyl hydrolase family 57 - - - 1.069e-240 766.0
HKD1_k127_3233141_30 radical SAM K06871 - - 0.00000000000000000000000000000000000000001668 165.0
HKD1_k127_3233141_31 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.000000000000000000000000000000000000005592 151.0
HKD1_k127_3233141_32 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000006654 148.0
HKD1_k127_3233141_33 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000001327 141.0
HKD1_k127_3233141_34 - - - - 0.00000000000000000000000000000000005153 140.0
HKD1_k127_3233141_35 - - - - 0.0000000000000000000000000000001196 140.0
HKD1_k127_3233141_36 - - - - 0.00000000000000000000000000003253 121.0
HKD1_k127_3233141_37 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000000001211 94.0
HKD1_k127_3233141_38 Acetyltransferase (GNAT) domain - - - 0.000000000000000000002095 94.0
HKD1_k127_3233141_39 cell cycle K05589,K12065,K13052 - - 0.00000000000003479 76.0
HKD1_k127_3233141_4 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 5.094e-200 640.0
HKD1_k127_3233141_5 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 617.0
HKD1_k127_3233141_6 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 546.0
HKD1_k127_3233141_7 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 469.0
HKD1_k127_3233141_8 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 456.0
HKD1_k127_3233141_9 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 441.0
HKD1_k127_3233648_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 450.0
HKD1_k127_3233648_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000001179 143.0
HKD1_k127_3233648_2 Smr domain - - - 0.000000000000000000000000001202 121.0
HKD1_k127_3233648_3 Membrane - - - 0.000000000000000000000006737 110.0
HKD1_k127_3237186_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 5.544e-310 975.0
HKD1_k127_3237186_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.496e-231 726.0
HKD1_k127_3237186_10 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000009617 115.0
HKD1_k127_3237186_11 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.00000000000000000000000007172 112.0
HKD1_k127_3237186_12 PFAM YcfA-like - - - 0.0000000000000000000000007732 105.0
HKD1_k127_3237186_13 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000009689 103.0
HKD1_k127_3237186_14 toxin-antitoxin pair type II binding K08591,K19159 GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 0.00000000000000000000002995 101.0
HKD1_k127_3237186_15 - - - - 0.00000000000001259 78.0
HKD1_k127_3237186_16 RecX family K03565 - - 0.00000000000003289 79.0
HKD1_k127_3237186_2 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 589.0
HKD1_k127_3237186_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 500.0
HKD1_k127_3237186_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 493.0
HKD1_k127_3237186_5 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 321.0
HKD1_k127_3237186_6 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000000000741 208.0
HKD1_k127_3237186_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000000000000000000000000009982 162.0
HKD1_k127_3237186_8 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000007289 124.0
HKD1_k127_3237186_9 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000001871 118.0
HKD1_k127_324562_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 512.0
HKD1_k127_324562_1 response regulator K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 491.0
HKD1_k127_324562_10 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000003745 115.0
HKD1_k127_324562_11 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000000004966 96.0
HKD1_k127_324562_2 histidine kinase, HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 355.0
HKD1_k127_324562_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002145 258.0
HKD1_k127_324562_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000002442 201.0
HKD1_k127_324562_5 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000001351 180.0
HKD1_k127_324562_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000002711 148.0
HKD1_k127_324562_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000005584 145.0
HKD1_k127_324562_8 copG family - - - 0.0000000000000000000000000000000007703 130.0
HKD1_k127_324562_9 response regulator - - - 0.0000000000000000000000000000001527 128.0
HKD1_k127_3261356_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 608.0
HKD1_k127_3261356_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 458.0
HKD1_k127_3261356_10 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008166 266.0
HKD1_k127_3261356_11 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003283 265.0
HKD1_k127_3261356_12 NosL - - - 0.0000000000000000000000000000000000000000001738 166.0
HKD1_k127_3261356_13 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000001621 116.0
HKD1_k127_3261356_14 PIN domain K07063 - - 0.00000000000000000000000001349 115.0
HKD1_k127_3261356_15 Predicted membrane protein (DUF2318) - - - 0.00000000000000000000009957 103.0
HKD1_k127_3261356_16 - - - - 0.000000000000000000001141 99.0
HKD1_k127_3261356_17 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.000000000000000003852 86.0
HKD1_k127_3261356_18 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.00000000000000001061 98.0
HKD1_k127_3261356_19 - - - - 0.00000000000003556 76.0
HKD1_k127_3261356_2 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007173 402.0
HKD1_k127_3261356_20 Protein of unknown function (DUF1573) - - - 0.00003416 54.0
HKD1_k127_3261356_3 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 386.0
HKD1_k127_3261356_4 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 380.0
HKD1_k127_3261356_5 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 332.0
HKD1_k127_3261356_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 303.0
HKD1_k127_3261356_7 Abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001721 282.0
HKD1_k127_3261356_8 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002467 288.0
HKD1_k127_3261356_9 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009138 272.0
HKD1_k127_3280617_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 331.0
HKD1_k127_3280617_1 Bacterial type II and III secretion system protein K02453,K03219 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 336.0
HKD1_k127_3280617_2 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000001282 130.0
HKD1_k127_3280617_3 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00005632 55.0
HKD1_k127_3280617_4 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.00007303 52.0
HKD1_k127_3287230_0 Multicopper oxidase K22350 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 596.0
HKD1_k127_3287230_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 422.0
HKD1_k127_3287230_2 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 374.0
HKD1_k127_3287230_3 Ribosomal RNA large subunit methyltransferase J K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000004548 211.0
HKD1_k127_3287230_4 Multicopper - - - 0.000000000000000000000000000000000000000000007414 166.0
HKD1_k127_3287230_5 Cupredoxin-like domain K02275 - 1.9.3.1 0.000000000000000000000000000004207 125.0
HKD1_k127_3302904_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1007.0
HKD1_k127_3302904_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 2.849e-318 997.0
HKD1_k127_3302904_10 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 367.0
HKD1_k127_3302904_11 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 364.0
HKD1_k127_3302904_12 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 327.0
HKD1_k127_3302904_13 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 288.0
HKD1_k127_3302904_14 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000001513 250.0
HKD1_k127_3302904_15 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000001328 204.0
HKD1_k127_3302904_16 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000005094 174.0
HKD1_k127_3302904_17 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000000000000000000000000000008084 166.0
HKD1_k127_3302904_18 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000008176 170.0
HKD1_k127_3302904_19 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000007964 153.0
HKD1_k127_3302904_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 3.203e-274 854.0
HKD1_k127_3302904_20 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000004247 154.0
HKD1_k127_3302904_21 - - - - 0.000000000000000000000000000000001051 134.0
HKD1_k127_3302904_22 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000001435 132.0
HKD1_k127_3302904_23 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000000225 125.0
HKD1_k127_3302904_24 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000004652 119.0
HKD1_k127_3302904_25 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000000002246 115.0
HKD1_k127_3302904_26 Cupredoxin-like domain - - - 0.00000000000000000000000001277 123.0
HKD1_k127_3302904_27 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000001272 107.0
HKD1_k127_3302904_28 - - - - 0.00000000000000000286 91.0
HKD1_k127_3302904_29 Amino acid permease - - - 0.00000000000000003032 88.0
HKD1_k127_3302904_3 Domain in cystathionine beta-synthase and other proteins. K07182 - - 1.325e-256 805.0
HKD1_k127_3302904_30 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000001292 61.0
HKD1_k127_3302904_31 cytochrome C - - - 0.000006787 57.0
HKD1_k127_3302904_4 glycolate transport K14393 - - 1.34e-223 711.0
HKD1_k127_3302904_5 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 588.0
HKD1_k127_3302904_6 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 606.0
HKD1_k127_3302904_7 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 492.0
HKD1_k127_3302904_8 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 460.0
HKD1_k127_3302904_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 421.0
HKD1_k127_3356339_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0 1067.0
HKD1_k127_3356339_1 Surface antigen K07277 - - 9.571e-248 788.0
HKD1_k127_3356339_10 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.00000000000000000000000001875 115.0
HKD1_k127_3356339_2 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 589.0
HKD1_k127_3356339_3 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 549.0
HKD1_k127_3356339_4 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 395.0
HKD1_k127_3356339_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 380.0
HKD1_k127_3356339_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 376.0
HKD1_k127_3356339_7 2Fe-2S -binding domain K13483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005164 264.0
HKD1_k127_3356339_8 Psort location Cytoplasmic, score 8.96 K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005259 268.0
HKD1_k127_3356339_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000001754 180.0
HKD1_k127_3372057_0 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 572.0
HKD1_k127_3372057_1 all-trans-retinol 13,14-reductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 560.0
HKD1_k127_3372057_10 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000004321 242.0
HKD1_k127_3372057_11 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002444 241.0
HKD1_k127_3372057_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000008566 222.0
HKD1_k127_3372057_13 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000002391 224.0
HKD1_k127_3372057_14 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000002816 205.0
HKD1_k127_3372057_15 Universal stress protein family K07090 - - 0.000000000000000000000000000000000000000000000000000148 196.0
HKD1_k127_3372057_16 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000000000000000000006976 194.0
HKD1_k127_3372057_17 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000001801 172.0
HKD1_k127_3372057_18 - - - - 0.0000000000000000000000000000000000000001541 160.0
HKD1_k127_3372057_19 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000001905 154.0
HKD1_k127_3372057_2 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 520.0
HKD1_k127_3372057_20 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity K00950,K13940 GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000000004317 148.0
HKD1_k127_3372057_21 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000008552 131.0
HKD1_k127_3372057_22 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.00000000000000000000000000000001578 133.0
HKD1_k127_3372057_23 nucleotidyltransferase activity K07075 - - 0.0000000000000000000000000006677 115.0
HKD1_k127_3372057_24 Histidine kinase - - - 0.000000000000000000000000116 118.0
HKD1_k127_3372057_25 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000003893 100.0
HKD1_k127_3372057_26 Belongs to the 'phage' integrase family - - - 0.00002471 48.0
HKD1_k127_3372057_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 383.0
HKD1_k127_3372057_4 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 374.0
HKD1_k127_3372057_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529,K18227,K18249 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 318.0
HKD1_k127_3372057_6 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 278.0
HKD1_k127_3372057_7 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001595 272.0
HKD1_k127_3372057_8 Pyruvate phosphate dikinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001153 254.0
HKD1_k127_3372057_9 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001113 252.0
HKD1_k127_3373519_0 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 554.0
HKD1_k127_3373519_1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 391.0
HKD1_k127_3373519_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000004285 228.0
HKD1_k127_3373519_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000002279 185.0
HKD1_k127_3373519_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000002289 121.0
HKD1_k127_342985_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1053.0
HKD1_k127_342985_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 580.0
HKD1_k127_342985_10 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000000004777 144.0
HKD1_k127_342985_11 YCII-related domain - - - 0.000000000000000000000000000000000005383 141.0
HKD1_k127_342985_12 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000447 97.0
HKD1_k127_342985_13 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000496 78.0
HKD1_k127_342985_14 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000001038 78.0
HKD1_k127_342985_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 400.0
HKD1_k127_342985_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 332.0
HKD1_k127_342985_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 292.0
HKD1_k127_342985_5 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000006369 256.0
HKD1_k127_342985_6 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001438 243.0
HKD1_k127_342985_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000006126 204.0
HKD1_k127_342985_8 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000000000000000000000000818 178.0
HKD1_k127_342985_9 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000001067 177.0
HKD1_k127_350129_0 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008642 363.0
HKD1_k127_350129_1 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 315.0
HKD1_k127_350129_2 MltA-interacting MipA family protein K07274 - - 0.0000000000000000000000000000000000000000000000000000001067 205.0
HKD1_k127_350129_3 Cysteine rich repeat - - - 0.0000000000000000000000000000000000000000007639 162.0
HKD1_k127_350129_4 YMGG-like Gly-zipper - - - 0.00000000000000000000000000000000000000007624 158.0
HKD1_k127_350129_5 Cysteine rich repeat - - - 0.00000000000000000006315 95.0
HKD1_k127_350129_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000001373 74.0
HKD1_k127_350129_7 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000001875 70.0
HKD1_k127_350129_8 - - - - 0.00000000001109 71.0
HKD1_k127_3504760_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 7.485e-205 646.0
HKD1_k127_3504760_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 2.033e-198 623.0
HKD1_k127_3504760_10 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000119 194.0
HKD1_k127_3504760_11 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000006279 181.0
HKD1_k127_3504760_12 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000347 179.0
HKD1_k127_3504760_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000431 174.0
HKD1_k127_3504760_14 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000008384 173.0
HKD1_k127_3504760_15 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000008983 128.0
HKD1_k127_3504760_16 Domain of unknown function (DUF370) K09777 - - 0.0000000000000000000000000005915 117.0
HKD1_k127_3504760_17 Tetratricopeptide repeat - - - 0.00000000000000000009587 101.0
HKD1_k127_3504760_18 Roadblock/LC7 domain - - - 0.000000000000000004791 88.0
HKD1_k127_3504760_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 504.0
HKD1_k127_3504760_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 370.0
HKD1_k127_3504760_4 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 328.0
HKD1_k127_3504760_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 307.0
HKD1_k127_3504760_6 Creatinase Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000004617 276.0
HKD1_k127_3504760_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000002202 243.0
HKD1_k127_3504760_8 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000005254 217.0
HKD1_k127_3504760_9 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000001521 199.0
HKD1_k127_3542295_0 FAD binding domain K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 619.0
HKD1_k127_3542295_1 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 468.0
HKD1_k127_3542295_2 PFAM HAMP domain, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, His Kinase A (phosphoacceptor) domain, Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 346.0
HKD1_k127_3542295_3 response regulator K02483,K07666,K07774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008637 258.0
HKD1_k127_3542295_4 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000001858 230.0
HKD1_k127_3542295_5 glycogen (starch) synthase activity - - - 0.0000000000000000000000000000000000000000000000001325 192.0
HKD1_k127_3542295_6 zinc-ribbon domain - - - 0.000000000000000000000000009612 118.0
HKD1_k127_3647028_0 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 380.0
HKD1_k127_3647028_1 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 312.0
HKD1_k127_3647028_10 overlaps another CDS with the same product name K02458 - - 0.0000001105 59.0
HKD1_k127_3647028_11 Prokaryotic N-terminal methylation motif K02459 - - 0.00002959 55.0
HKD1_k127_3647028_12 - - - - 0.0002224 51.0
HKD1_k127_3647028_2 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000001409 184.0
HKD1_k127_3647028_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000002283 147.0
HKD1_k127_3647028_4 PFAM Type II secretion system protein E K02454 - - 0.0000000000000000000000000000000004442 134.0
HKD1_k127_3647028_5 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000002353 136.0
HKD1_k127_3647028_6 Iron-sulfur cluster-binding domain - - - 0.000000000006266 76.0
HKD1_k127_3647028_7 Type II secretion system (T2SS), protein M subtype b - - - 0.0000000005937 68.0
HKD1_k127_3647028_8 PFAM Fimbrial assembly K02461 - - 0.000000001699 70.0
HKD1_k127_3647028_9 General secretion pathway protein H K02457 - - 0.000000003131 64.0
HKD1_k127_3715628_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 605.0
HKD1_k127_3715628_1 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 495.0
HKD1_k127_3715628_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000002459 258.0
HKD1_k127_3715628_3 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000006196 229.0
HKD1_k127_3715628_4 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000000001028 192.0
HKD1_k127_3715628_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000003522 107.0
HKD1_k127_3715628_6 phosphate starvation-inducible protein K06217 - - 0.00000000000000000001698 91.0
HKD1_k127_3771389_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 597.0
HKD1_k127_3771389_1 glycogen (starch) synthase activity - - - 0.0000000000000000000000000000000000000000000000000001785 201.0
HKD1_k127_3771389_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000002128 137.0
HKD1_k127_3771389_3 GlcNAc-PI de-N-acetylase K01463,K20444 - - 0.000000000000000000000000000528 122.0
HKD1_k127_3771389_4 Glycosyl transferases group 1 - - - 0.00000000003554 65.0
HKD1_k127_3797890_0 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 3.949e-314 975.0
HKD1_k127_3797890_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 503.0
HKD1_k127_3797890_10 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005974 259.0
HKD1_k127_3797890_11 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008364 250.0
HKD1_k127_3797890_12 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000491 213.0
HKD1_k127_3797890_13 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000001082 185.0
HKD1_k127_3797890_14 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000005261 165.0
HKD1_k127_3797890_15 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000000008512 149.0
HKD1_k127_3797890_16 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000007597 144.0
HKD1_k127_3797890_17 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000001096 137.0
HKD1_k127_3797890_18 lipopolysaccharide metabolic process K19302 - 3.6.1.27 0.00000000001507 75.0
HKD1_k127_3797890_19 Kinase domain K12132 - 2.7.11.1 0.00000000005233 70.0
HKD1_k127_3797890_2 histidine kinase A domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 472.0
HKD1_k127_3797890_21 transferase activity, transferring glycosyl groups - - - 0.000003854 55.0
HKD1_k127_3797890_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 455.0
HKD1_k127_3797890_4 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 434.0
HKD1_k127_3797890_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007268 378.0
HKD1_k127_3797890_6 ATPases associated with a variety of cellular activities K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 301.0
HKD1_k127_3797890_7 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 284.0
HKD1_k127_3797890_8 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000515 270.0
HKD1_k127_3797890_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000002887 267.0
HKD1_k127_381980_0 Belongs to the aldehyde dehydrogenase family K13821 - 1.2.1.88,1.5.5.2 2.7e-322 1015.0
HKD1_k127_381980_1 GAF domain - - - 5.033e-208 698.0
HKD1_k127_381980_2 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 584.0
HKD1_k127_381980_3 CoA binding domain K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 504.0
HKD1_k127_381980_4 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 497.0
HKD1_k127_381980_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 418.0
HKD1_k127_381980_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000001522 258.0
HKD1_k127_381980_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000001247 235.0
HKD1_k127_381980_8 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000001585 173.0
HKD1_k127_381980_9 - - - - 0.00000000000000000004024 97.0
HKD1_k127_3875698_0 DHHA2 domain K15986 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 565.0
HKD1_k127_3875698_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 483.0
HKD1_k127_3875698_10 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000004705 73.0
HKD1_k127_3875698_11 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.00000000427 65.0
HKD1_k127_3875698_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 456.0
HKD1_k127_3875698_3 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000211 273.0
HKD1_k127_3875698_4 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000354 262.0
HKD1_k127_3875698_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000001383 231.0
HKD1_k127_3875698_6 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000033 196.0
HKD1_k127_3875698_7 Domain of unknown function (DUF202) K00389 - - 0.0000000000000000000000000000000000000000008581 163.0
HKD1_k127_3875698_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000002864 108.0
HKD1_k127_3875698_9 - - - - 0.00000000000000000000000004648 108.0
HKD1_k127_3917213_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 352.0
HKD1_k127_3917213_1 NADPH-dependent FMN reductase K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000002701 202.0
HKD1_k127_3917213_10 Predicted membrane protein (DUF2318) K09005 - - 0.0000000002893 66.0
HKD1_k127_3917213_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000002818 203.0
HKD1_k127_3917213_3 HNH nucleases - - - 0.000000000000000000000000000000000000000000000003265 175.0
HKD1_k127_3917213_4 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000001014 162.0
HKD1_k127_3917213_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000005346 152.0
HKD1_k127_3917213_7 - - - - 0.000000000000000000000004156 103.0
HKD1_k127_3917213_8 - - - - 0.00000000000000000003174 97.0
HKD1_k127_3917213_9 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000006306 82.0
HKD1_k127_3993731_0 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 433.0
HKD1_k127_3993731_1 Oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003417 282.0
HKD1_k127_3993731_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006037 244.0
HKD1_k127_3993731_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004749 243.0
HKD1_k127_3993731_4 DRTGG domain K06873 - - 0.00000000000000000000000000158 114.0
HKD1_k127_3993731_5 heat shock protein binding - - - 0.000000001947 70.0
HKD1_k127_4016842_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 545.0
HKD1_k127_4016842_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 531.0
HKD1_k127_4016842_10 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.00000000000000000000000000000000000000114 171.0
HKD1_k127_4016842_11 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000007006 148.0
HKD1_k127_4016842_12 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000000000000000000008546 154.0
HKD1_k127_4016842_13 Two component signalling adaptor domain K03408 - - 0.000000000000000003961 93.0
HKD1_k127_4016842_15 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000004544 54.0
HKD1_k127_4016842_16 chemotaxis protein K03406 - - 0.00003369 56.0
HKD1_k127_4016842_2 Galactose oxidase, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 333.0
HKD1_k127_4016842_3 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 295.0
HKD1_k127_4016842_4 response regulator K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 294.0
HKD1_k127_4016842_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001235 307.0
HKD1_k127_4016842_6 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001099 275.0
HKD1_k127_4016842_7 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001179 274.0
HKD1_k127_4016842_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000398 265.0
HKD1_k127_4016842_9 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008532 271.0
HKD1_k127_4047645_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1600.0
HKD1_k127_4047645_1 Belongs to the complex I 49 kDa subunit family K00333,K14090 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 478.0
HKD1_k127_4047645_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 308.0
HKD1_k127_4047645_3 4Fe-4S dicluster domain K14091 - - 0.0000000000000000000000000000000001259 137.0
HKD1_k127_4047645_4 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000008898 110.0
HKD1_k127_4074911_0 Endoribonuclease that initiates mRNA decay K18682 - - 2.58e-206 659.0
HKD1_k127_4074911_1 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 458.0
HKD1_k127_4074911_2 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 321.0
HKD1_k127_4074911_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 326.0
HKD1_k127_4074911_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000001028 217.0
HKD1_k127_4074911_5 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.0000000000000000000000000000000000000000000000000000004295 203.0
HKD1_k127_4074911_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000005042 94.0
HKD1_k127_4074911_7 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 0.0000000000000000123 86.0
HKD1_k127_4074911_8 Bacterial SH3 domain - - - 0.0008573 46.0
HKD1_k127_4107183_0 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.0 1093.0
HKD1_k127_4107183_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1088.0
HKD1_k127_4107183_10 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 429.0
HKD1_k127_4107183_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 411.0
HKD1_k127_4107183_12 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 410.0
HKD1_k127_4107183_13 Cytochrome b/b6/petB K00412,K03888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 399.0
HKD1_k127_4107183_14 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 371.0
HKD1_k127_4107183_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 336.0
HKD1_k127_4107183_16 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 336.0
HKD1_k127_4107183_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 306.0
HKD1_k127_4107183_18 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 295.0
HKD1_k127_4107183_19 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000001022 210.0
HKD1_k127_4107183_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 9.873e-290 899.0
HKD1_k127_4107183_20 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000001387 178.0
HKD1_k127_4107183_21 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000005182 177.0
HKD1_k127_4107183_22 SPTR Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000005623 162.0
HKD1_k127_4107183_23 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000000002157 153.0
HKD1_k127_4107183_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000002067 144.0
HKD1_k127_4107183_26 response regulator - - - 0.00000000000000000000000000000000000187 151.0
HKD1_k127_4107183_27 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000002975 141.0
HKD1_k127_4107183_28 - - - - 0.00000000000000000000000000000001792 130.0
HKD1_k127_4107183_29 electron transfer activity K00428 - 1.11.1.5 0.000000000000000000000000001468 117.0
HKD1_k127_4107183_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 4.651e-240 756.0
HKD1_k127_4107183_30 cheY-homologous receiver domain - - - 0.0000001343 61.0
HKD1_k127_4107183_31 Regulatory protein, FmdB family - - - 0.000007971 50.0
HKD1_k127_4107183_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 7.386e-236 737.0
HKD1_k127_4107183_5 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 6.49e-207 650.0
HKD1_k127_4107183_6 Domain of unknown function (DUF4139) - - - 1.871e-200 634.0
HKD1_k127_4107183_7 Proton-conducting membrane transporter K00342 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 599.0
HKD1_k127_4107183_8 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 488.0
HKD1_k127_4107183_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 480.0
HKD1_k127_4228083_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 6.816e-231 724.0
HKD1_k127_4228083_1 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 546.0
HKD1_k127_4228083_10 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000001179 122.0
HKD1_k127_4228083_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 528.0
HKD1_k127_4228083_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 512.0
HKD1_k127_4228083_4 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 384.0
HKD1_k127_4228083_5 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 326.0
HKD1_k127_4228083_6 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000009293 234.0
HKD1_k127_4228083_7 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000009823 226.0
HKD1_k127_4228083_8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000002377 202.0
HKD1_k127_4228083_9 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000002677 191.0
HKD1_k127_4301873_0 Elongation factor G, domain IV K02355 - - 9.226e-244 772.0
HKD1_k127_4301873_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 546.0
HKD1_k127_4301873_10 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000001486 243.0
HKD1_k127_4301873_11 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000007407 231.0
HKD1_k127_4301873_12 dTDP-4-dehydrorhamnose 3,5-epimerase - - - 0.0000000000000000000000000000000000000000000008835 171.0
HKD1_k127_4301873_13 Glycosyltransferase like family 2 - - - 0.000000000000000000000001563 115.0
HKD1_k127_4301873_14 DUF218 domain - - - 0.0000000000000000000002106 105.0
HKD1_k127_4301873_15 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00000000000000005235 86.0
HKD1_k127_4301873_16 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0000000000284 66.0
HKD1_k127_4301873_17 YtxH-like protein - - - 0.00000004169 56.0
HKD1_k127_4301873_18 Bacterial membrane protein, YfhO - - - 0.000003309 61.0
HKD1_k127_4301873_19 - - - - 0.00002943 54.0
HKD1_k127_4301873_2 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 471.0
HKD1_k127_4301873_20 - - - - 0.0001216 51.0
HKD1_k127_4301873_21 - - - - 0.0007654 48.0
HKD1_k127_4301873_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 449.0
HKD1_k127_4301873_4 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 439.0
HKD1_k127_4301873_5 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 422.0
HKD1_k127_4301873_6 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 400.0
HKD1_k127_4301873_7 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 392.0
HKD1_k127_4301873_8 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 312.0
HKD1_k127_4301873_9 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001586 284.0
HKD1_k127_4303083_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1315.0
HKD1_k127_4303083_1 Aldehyde dehydrogenase family K22187 - - 7.845e-199 631.0
HKD1_k127_4303083_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 576.0
HKD1_k127_4303083_3 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 556.0
HKD1_k127_4303083_4 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 405.0
HKD1_k127_4309976_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.251e-260 817.0
HKD1_k127_4309976_1 Sigma-54 interaction domain - - - 2.818e-208 657.0
HKD1_k127_4309976_10 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000008851 185.0
HKD1_k127_4309976_11 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.00000000000000000000000000000003069 132.0
HKD1_k127_4309976_12 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000001189 113.0
HKD1_k127_4309976_13 - - - - 0.00000000000000002355 84.0
HKD1_k127_4309976_14 isochorismatase - - - 0.000000005667 58.0
HKD1_k127_4309976_2 membrane transporter protein K07090 - - 1.319e-197 624.0
HKD1_k127_4309976_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 515.0
HKD1_k127_4309976_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 347.0
HKD1_k127_4309976_5 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 319.0
HKD1_k127_4309976_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009406 273.0
HKD1_k127_4309976_7 PFAM UspA - - - 0.000000000000000000000000000000000000000000000000000000000003818 218.0
HKD1_k127_4309976_8 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000005504 189.0
HKD1_k127_4309976_9 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000001795 185.0
HKD1_k127_4339964_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 592.0
HKD1_k127_4339964_1 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 575.0
HKD1_k127_4339964_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 550.0
HKD1_k127_4339964_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 508.0
HKD1_k127_4339964_4 PFAM peptidase K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 407.0
HKD1_k127_4339964_5 PFAM ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 379.0
HKD1_k127_4339964_6 Belongs to the MurCDEF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 299.0
HKD1_k127_4339964_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000001765 212.0
HKD1_k127_4339964_8 nucleotide metabolic process - - - 0.00000000000000000000000000000004207 130.0
HKD1_k127_4363703_0 PFAM Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 305.0
HKD1_k127_4363703_1 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 285.0
HKD1_k127_4363703_2 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002052 275.0
HKD1_k127_4363703_3 ABC transporter K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000002109 267.0
HKD1_k127_4363703_4 MoeZ MoeB domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006665 257.0
HKD1_k127_4363703_5 Elongator protein 3, MiaB family, Radical SAM K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007859 243.0
HKD1_k127_4377432_0 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 329.0
HKD1_k127_4377432_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000009475 224.0
HKD1_k127_4377432_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000004242 211.0
HKD1_k127_4377432_3 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000007093 194.0
HKD1_k127_4377432_4 SMART Cold shock protein K03704 - - 0.00000000000000000000000001001 109.0
HKD1_k127_4377432_5 - - - - 0.0000000000000000000000001317 120.0
HKD1_k127_4377432_6 - - - - 0.000000000000005915 77.0
HKD1_k127_4397786_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 574.0
HKD1_k127_4397786_1 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 535.0
HKD1_k127_4397786_10 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000002391 165.0
HKD1_k127_4397786_11 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000004641 164.0
HKD1_k127_4397786_12 Methyltransferase domain - - - 0.0000000000000000000000000000002057 132.0
HKD1_k127_4397786_13 TIGRFAM Protein of - - - 0.00000000000000000000000004682 108.0
HKD1_k127_4397786_15 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000001014 103.0
HKD1_k127_4397786_16 ACT domain protein - - - 0.0000000000588 68.0
HKD1_k127_4397786_17 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.0003415 46.0
HKD1_k127_4397786_2 GHKL domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 497.0
HKD1_k127_4397786_3 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 307.0
HKD1_k127_4397786_4 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006924 281.0
HKD1_k127_4397786_5 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004065 266.0
HKD1_k127_4397786_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000969 263.0
HKD1_k127_4397786_7 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000004929 199.0
HKD1_k127_4397786_8 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000002793 195.0
HKD1_k127_4397786_9 Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000001743 167.0
HKD1_k127_4411414_0 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 457.0
HKD1_k127_4411414_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 398.0
HKD1_k127_4411414_2 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 319.0
HKD1_k127_4411414_3 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000009918 247.0
HKD1_k127_4411414_4 - - - - 0.00000000000000000000000000000000000000000001017 166.0
HKD1_k127_4411414_5 Universal stress protein family K07090 - - 0.0000000000000000000000000000004949 127.0
HKD1_k127_4411414_6 UTRA K03710 - - 0.0000000000000000000000000000008648 131.0
HKD1_k127_4411540_0 Alpha amylase, catalytic domain - - - 2.962e-236 739.0
HKD1_k127_4411540_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 392.0
HKD1_k127_4411540_2 esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 374.0
HKD1_k127_4411540_3 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 302.0
HKD1_k127_4422276_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 501.0
HKD1_k127_4422276_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 373.0
HKD1_k127_4422276_2 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000007774 228.0
HKD1_k127_4422276_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000002473 228.0
HKD1_k127_4440993_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 527.0
HKD1_k127_4440993_1 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 301.0
HKD1_k127_4440993_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000005985 213.0
HKD1_k127_4446599_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 309.0
HKD1_k127_4446599_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001968 272.0
HKD1_k127_4446599_10 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000002314 124.0
HKD1_k127_4446599_11 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00005155 48.0
HKD1_k127_4446599_12 Protein of unknown function (DUF1670) - - - 0.00005458 49.0
HKD1_k127_4446599_13 DNA-binding transcription factor activity K02444,K03655 - 3.6.4.12 0.0001126 49.0
HKD1_k127_4446599_2 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000009766 241.0
HKD1_k127_4446599_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000004122 232.0
HKD1_k127_4446599_4 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000005046 209.0
HKD1_k127_4446599_5 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000002016 209.0
HKD1_k127_4446599_6 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005509,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903135 - 0.000000000000000000000000000000000000000000000000000001435 203.0
HKD1_k127_4446599_7 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000005621 193.0
HKD1_k127_4446599_8 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000003199 189.0
HKD1_k127_4446599_9 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000008147 124.0
HKD1_k127_4459550_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 596.0
HKD1_k127_4459550_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 592.0
HKD1_k127_4459550_10 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009495 290.0
HKD1_k127_4459550_11 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003686 276.0
HKD1_k127_4459550_12 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000005224 244.0
HKD1_k127_4459550_13 metal ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000002155 227.0
HKD1_k127_4459550_14 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000008732 198.0
HKD1_k127_4459550_15 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000001298 190.0
HKD1_k127_4459550_16 ferredoxin-thioredoxin reductase activity - - - 0.00000000000000000000000000000000000001564 146.0
HKD1_k127_4459550_17 SWI complex, BAF60b domains - - - 0.00000000000000000000000000000000002819 138.0
HKD1_k127_4459550_18 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000006157 138.0
HKD1_k127_4459550_19 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.0000000000000000000000387 104.0
HKD1_k127_4459550_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 561.0
HKD1_k127_4459550_20 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000009646 90.0
HKD1_k127_4459550_22 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000003411 72.0
HKD1_k127_4459550_24 Protein of unknown function (DUF721) - - - 0.00007684 52.0
HKD1_k127_4459550_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 558.0
HKD1_k127_4459550_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 499.0
HKD1_k127_4459550_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 361.0
HKD1_k127_4459550_6 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 365.0
HKD1_k127_4459550_7 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 328.0
HKD1_k127_4459550_8 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 307.0
HKD1_k127_4459550_9 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002405 284.0
HKD1_k127_4668736_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 1.836e-274 867.0
HKD1_k127_4668736_1 3-hydroxyacyl-CoA dehydrogenase K00074,K01782 - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 372.0
HKD1_k127_4668736_2 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 312.0
HKD1_k127_4668736_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000004315 261.0
HKD1_k127_4668736_4 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000774 256.0
HKD1_k127_4668736_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000001912 235.0
HKD1_k127_4668736_6 pfam nudix - - - 0.00000000000000000000000000000000000000000000000000008313 190.0
HKD1_k127_4668736_7 Histidine kinase K02660,K11525 - - 0.000000000000000000000000000001019 132.0
HKD1_k127_4668736_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000008667 93.0
HKD1_k127_4668736_9 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000006062 78.0
HKD1_k127_4687265_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 456.0
HKD1_k127_4687265_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 364.0
HKD1_k127_4687265_10 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000005378 210.0
HKD1_k127_4687265_11 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000228 203.0
HKD1_k127_4687265_12 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000001047 202.0
HKD1_k127_4687265_13 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000003672 193.0
HKD1_k127_4687265_14 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000025 172.0
HKD1_k127_4687265_15 competence protein - - - 0.00000000000000000000000000000000000000000004196 171.0
HKD1_k127_4687265_16 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000004736 171.0
HKD1_k127_4687265_17 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000001287 159.0
HKD1_k127_4687265_18 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000002069 152.0
HKD1_k127_4687265_19 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000001155 145.0
HKD1_k127_4687265_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 347.0
HKD1_k127_4687265_20 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000000444 134.0
HKD1_k127_4687265_21 Glutathione peroxidase - - - 0.0000000000000000000000000009093 119.0
HKD1_k127_4687265_22 Bacterial PH domain - - - 0.00000000000002741 79.0
HKD1_k127_4687265_24 Glycolate oxidase subunit K00104 - 1.1.3.15 0.00000002786 55.0
HKD1_k127_4687265_27 PDZ DHR GLGF domain protein - - - 0.0003891 51.0
HKD1_k127_4687265_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 338.0
HKD1_k127_4687265_4 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 316.0
HKD1_k127_4687265_5 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004516 289.0
HKD1_k127_4687265_6 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008835 276.0
HKD1_k127_4687265_7 cytochrome complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000567 244.0
HKD1_k127_4687265_8 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000001536 231.0
HKD1_k127_4687265_9 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000002552 220.0
HKD1_k127_4724783_0 Major Facilitator Superfamily K02575 - - 1.752e-283 880.0
HKD1_k127_4724783_1 Nitrate reductase, beta subunit K00371,K17051 - 1.7.5.1 3.274e-240 750.0
HKD1_k127_4724783_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 7.204e-199 624.0
HKD1_k127_4724783_3 TIGRFAM respiratory nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001576 282.0
HKD1_k127_4724783_4 TIGRFAM nitrate reductase molybdenum cofactor assembly chaperone K00373 - - 0.0000000000000000000000000000000000000000001934 167.0
HKD1_k127_4724783_5 sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.0000000000000000000000165 103.0
HKD1_k127_4764892_0 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 445.0
HKD1_k127_4764892_1 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000006199 207.0
HKD1_k127_4764892_2 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000005436 180.0
HKD1_k127_4764892_3 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000000000003023 172.0
HKD1_k127_4780811_0 Heat shock 70 kDa protein K04043 - - 0.0 1009.0
HKD1_k127_4780811_1 C-terminal, D2-small domain, of ClpB protein K03694 - - 9.496e-289 907.0
HKD1_k127_4780811_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 454.0
HKD1_k127_4780811_11 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 439.0
HKD1_k127_4780811_12 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 416.0
HKD1_k127_4780811_13 cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 378.0
HKD1_k127_4780811_14 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 367.0
HKD1_k127_4780811_15 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 362.0
HKD1_k127_4780811_16 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 352.0
HKD1_k127_4780811_17 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 300.0
HKD1_k127_4780811_18 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000154 289.0
HKD1_k127_4780811_19 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002638 302.0
HKD1_k127_4780811_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 7.475e-239 747.0
HKD1_k127_4780811_20 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002793 279.0
HKD1_k127_4780811_21 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000002526 214.0
HKD1_k127_4780811_22 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000001437 205.0
HKD1_k127_4780811_23 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000001348 203.0
HKD1_k127_4780811_24 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000004189 190.0
HKD1_k127_4780811_25 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000669 161.0
HKD1_k127_4780811_26 YceI-like domain - - - 0.0000000000000000000000000000000000000004288 156.0
HKD1_k127_4780811_27 - - - - 0.0000000000000000000000000000000000002503 162.0
HKD1_k127_4780811_28 Universal stress protein family - - - 0.000000000000000000000000000000000001771 143.0
HKD1_k127_4780811_29 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000006326 138.0
HKD1_k127_4780811_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.926e-227 721.0
HKD1_k127_4780811_30 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000004248 122.0
HKD1_k127_4780811_31 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000005823 118.0
HKD1_k127_4780811_32 - - - - 0.00000000000000000000009428 106.0
HKD1_k127_4780811_33 Cold shock protein domain K03704 - - 0.000000000005419 66.0
HKD1_k127_4780811_34 Protein of unknown function (DUF2934) - - - 0.0000000184 59.0
HKD1_k127_4780811_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.144e-226 712.0
HKD1_k127_4780811_5 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 532.0
HKD1_k127_4780811_6 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 502.0
HKD1_k127_4780811_7 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 506.0
HKD1_k127_4780811_8 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 501.0
HKD1_k127_4780811_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 459.0
HKD1_k127_4845085_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 466.0
HKD1_k127_4845085_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 437.0
HKD1_k127_4845085_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 345.0
HKD1_k127_4845085_3 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000004185 134.0
HKD1_k127_4845085_4 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.00000000002228 74.0
HKD1_k127_490098_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 6.858e-202 640.0
HKD1_k127_490098_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 481.0
HKD1_k127_490098_2 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 340.0
HKD1_k127_490098_3 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 321.0
HKD1_k127_490098_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000009749 261.0
HKD1_k127_490098_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000002229 236.0
HKD1_k127_490098_6 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000004372 224.0
HKD1_k127_490098_8 - - - - 0.00000000000005417 76.0
HKD1_k127_4916728_0 Protein conserved in bacteria - - - 1.378e-222 716.0
HKD1_k127_4916728_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 578.0
HKD1_k127_4916728_10 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000001095 126.0
HKD1_k127_4916728_12 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000000001153 100.0
HKD1_k127_4916728_13 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0006148 46.0
HKD1_k127_4916728_2 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 436.0
HKD1_k127_4916728_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 403.0
HKD1_k127_4916728_4 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003092 263.0
HKD1_k127_4916728_5 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005039 256.0
HKD1_k127_4916728_6 PFAM Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000003932 225.0
HKD1_k127_4916728_7 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000448 151.0
HKD1_k127_4916728_8 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000002051 150.0
HKD1_k127_4916728_9 Thioredoxin - - - 0.0000000000000000000000000000000008142 143.0
HKD1_k127_50332_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001841 239.0
HKD1_k127_50332_1 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000005929 186.0
HKD1_k127_50332_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000003925 159.0
HKD1_k127_50332_3 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.00000000000000000000005618 115.0
HKD1_k127_50332_4 lipolytic protein G-D-S-L family - - - 0.0000000000000000000001591 111.0
HKD1_k127_50332_5 PFAM glycosyl transferase family 39 K00728 - 2.4.1.109 0.00000000000000001261 95.0
HKD1_k127_50332_6 Alternative locus ID K00612 - - 0.0000000000001321 70.0
HKD1_k127_50332_7 - - - - 0.000000000001429 68.0
HKD1_k127_5057924_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535 - 3.6.3.6 3.726e-291 914.0
HKD1_k127_5057924_1 GTP-binding GTPase Middle Region K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 608.0
HKD1_k127_5057924_10 SMART Cold shock protein K03704 - - 0.000000000000000000000000002759 112.0
HKD1_k127_5057924_11 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000006334 72.0
HKD1_k127_5057924_12 transglycosylase - - - 0.00000003009 63.0
HKD1_k127_5057924_2 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 589.0
HKD1_k127_5057924_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 453.0
HKD1_k127_5057924_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 422.0
HKD1_k127_5057924_5 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 358.0
HKD1_k127_5057924_6 endonuclease III K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 302.0
HKD1_k127_5057924_7 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000004092 228.0
HKD1_k127_5057924_8 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000009045 226.0
HKD1_k127_5057924_9 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000008299 202.0
HKD1_k127_5085030_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1225.0
HKD1_k127_5085030_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1054.0
HKD1_k127_5085030_2 Phosphoglucose isomerase K01810 - 5.3.1.9 4.674e-272 843.0
HKD1_k127_5085030_3 Phosphofructokinase K00850 - 2.7.1.11 2.605e-201 634.0
HKD1_k127_5085030_4 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 573.0
HKD1_k127_5085030_5 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 555.0
HKD1_k127_5085030_6 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000762 159.0
HKD1_k127_5095740_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.044e-280 876.0
HKD1_k127_5095740_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 491.0
HKD1_k127_5095740_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 455.0
HKD1_k127_5095740_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000002069 181.0
HKD1_k127_5095740_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000144 153.0
HKD1_k127_5095740_5 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000007681 151.0
HKD1_k127_5095740_6 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000139 90.0
HKD1_k127_5095740_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.0000000000000003209 91.0
HKD1_k127_5095740_8 mercury ion transmembrane transporter activity K07213 - - 0.00000000000004158 74.0
HKD1_k127_5104501_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 4.987e-197 628.0
HKD1_k127_5104501_1 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 588.0
HKD1_k127_5104501_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 508.0
HKD1_k127_5104501_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 355.0
HKD1_k127_5104501_4 CO dehydrogenase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 312.0
HKD1_k127_5104501_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008263 279.0
HKD1_k127_5104501_6 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000000000000000000000000000000000001003 149.0
HKD1_k127_5104501_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000007834 125.0
HKD1_k127_5104501_8 Phospholipid methyltransferase - - - 0.00000000000000000001225 100.0
HKD1_k127_5157472_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 4.107e-281 883.0
HKD1_k127_5157472_1 Dehydratase family K01687 - 4.2.1.9 3.137e-258 806.0
HKD1_k127_5157472_10 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 314.0
HKD1_k127_5157472_11 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003112 272.0
HKD1_k127_5157472_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000007013 256.0
HKD1_k127_5157472_13 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000003381 228.0
HKD1_k127_5157472_14 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000001069 223.0
HKD1_k127_5157472_15 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000004677 209.0
HKD1_k127_5157472_16 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000000000000000000000001052 204.0
HKD1_k127_5157472_17 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000006505 194.0
HKD1_k127_5157472_18 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000001235 180.0
HKD1_k127_5157472_19 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000001413 180.0
HKD1_k127_5157472_2 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 1.128e-237 751.0
HKD1_k127_5157472_20 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000002421 124.0
HKD1_k127_5157472_22 Protein of unknown function (DUF465) K09794 - - 0.000000000000000007915 85.0
HKD1_k127_5157472_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 421.0
HKD1_k127_5157472_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 417.0
HKD1_k127_5157472_5 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 373.0
HKD1_k127_5157472_6 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 369.0
HKD1_k127_5157472_7 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 340.0
HKD1_k127_5157472_8 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 355.0
HKD1_k127_5157472_9 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 316.0
HKD1_k127_5162528_0 TIGRFAM Ammonium transporter K03320 - - 1.023e-245 769.0
HKD1_k127_5162528_1 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 513.0
HKD1_k127_5162528_2 Serine/threonine phosphatases, family 2C, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 456.0
HKD1_k127_5162528_3 - K09771 - - 0.000000000000000000000000000000000000000001967 158.0
HKD1_k127_5162528_4 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000001752 68.0
HKD1_k127_5164494_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 1.168e-198 654.0
HKD1_k127_5164494_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 572.0
HKD1_k127_5164494_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 549.0
HKD1_k127_5164494_3 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 314.0
HKD1_k127_5164494_4 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000008006 229.0
HKD1_k127_5164494_5 PFAM Phosphomethylpyrimidine kinase type-1 K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000005803 211.0
HKD1_k127_5164494_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000002118 199.0
HKD1_k127_5164494_7 adenylate kinase activity K00939,K01939 - 2.7.4.3,6.3.4.4 0.00000000000000000000000000000000000000000000000005754 187.0
HKD1_k127_5164494_8 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000006506 156.0
HKD1_k127_5188501_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.145e-281 878.0
HKD1_k127_5188501_1 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 3.858e-194 626.0
HKD1_k127_5188501_2 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 544.0
HKD1_k127_5188501_3 HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide K12138,K12139,K15829 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 340.0
HKD1_k127_5188501_4 Proton-conducting membrane transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002418 256.0
HKD1_k127_5188501_5 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000033 242.0
HKD1_k127_5188501_6 haloacid dehalogenase-like hydrolase - - - 0.00009787 45.0
HKD1_k127_5193100_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1885.0
HKD1_k127_5193100_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1701.0
HKD1_k127_5193100_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 355.0
HKD1_k127_5193100_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001661 259.0
HKD1_k127_5193100_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000002607 211.0
HKD1_k127_5193100_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000000002034 196.0
HKD1_k127_5193100_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000004067 149.0
HKD1_k127_5193100_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000006028 92.0
HKD1_k127_5193100_8 Ribosomal protein L33 K02913 - - 0.00000000000000305 76.0
HKD1_k127_5193100_9 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000001494 70.0
HKD1_k127_5201803_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1630.0
HKD1_k127_5201803_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07789,K18138 - - 0.0 1516.0
HKD1_k127_5201803_10 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 442.0
HKD1_k127_5201803_11 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 426.0
HKD1_k127_5201803_12 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 421.0
HKD1_k127_5201803_13 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 353.0
HKD1_k127_5201803_14 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 316.0
HKD1_k127_5201803_15 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 303.0
HKD1_k127_5201803_16 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 303.0
HKD1_k127_5201803_17 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001223 280.0
HKD1_k127_5201803_18 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000003344 200.0
HKD1_k127_5201803_19 Putative transmembrane protein (Alph_Pro_TM) - - - 0.0000000000000000000000000000000000000000000005166 177.0
HKD1_k127_5201803_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1132.0
HKD1_k127_5201803_20 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000001601 173.0
HKD1_k127_5201803_21 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000004391 167.0
HKD1_k127_5201803_22 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000006767 159.0
HKD1_k127_5201803_23 - - - - 0.000000000000000000000000000000000000227 154.0
HKD1_k127_5201803_24 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000000000000000000000006853 145.0
HKD1_k127_5201803_25 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000005328 139.0
HKD1_k127_5201803_26 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000002294 136.0
HKD1_k127_5201803_27 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000001772 126.0
HKD1_k127_5201803_28 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.00000000000000000000000000002054 121.0
HKD1_k127_5201803_29 Putative regulatory protein - - - 0.000000000000000000001925 96.0
HKD1_k127_5201803_3 ABC transporter K06020 - 3.6.3.25 5.205e-306 944.0
HKD1_k127_5201803_30 Cytochrome c - - - 0.00000000000000001799 86.0
HKD1_k127_5201803_32 PFAM UspA - - - 0.0000000000000008213 82.0
HKD1_k127_5201803_33 YtxH-like protein - - - 0.0000000000005399 74.0
HKD1_k127_5201803_34 cyclic nucleotide binding K10187,K21562 - 4.1.99.16,4.2.3.22,4.2.3.75 0.000000104 63.0
HKD1_k127_5201803_35 cheY-homologous receiver domain - - - 0.000005122 53.0
HKD1_k127_5201803_4 Putative diguanylate phosphodiesterase - - - 9.774e-194 638.0
HKD1_k127_5201803_5 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 593.0
HKD1_k127_5201803_6 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 528.0
HKD1_k127_5201803_7 Outer membrane efflux protein K18903 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 524.0
HKD1_k127_5201803_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 494.0
HKD1_k127_5201803_9 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 464.0
HKD1_k127_5248869_0 Nitrogenase component 1 type Oxidoreductase K02587 - - 2.24e-280 885.0
HKD1_k127_5248869_1 Nitrogenase protein alpha chain K02586 - 1.18.6.1 9.158e-236 741.0
HKD1_k127_5248869_2 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 2.804e-230 727.0
HKD1_k127_5248869_3 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588,K04037,K11333 - 1.18.6.1,1.3.7.14,1.3.7.15,1.3.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 484.0
HKD1_k127_5248869_4 cyclic diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000002607 237.0
HKD1_k127_5248869_5 Nitrogen regulatory protein P-II K02590 - - 0.0000000000000000000000000000000000000000000000000000005517 197.0
HKD1_k127_5248869_6 Nitrogen regulatory protein P-II K02589 - - 0.000000000000000000000000000000000000000000000000005108 183.0
HKD1_k127_5248869_7 lyase activity - - - 0.000000000000000000000000000000000000000000000000492 196.0
HKD1_k127_5248869_8 Dinitrogenase iron-molybdenum cofactor K02596 - - 0.000000000000000000000000000000000000000001094 160.0
HKD1_k127_5248869_9 4Fe-4S dicluster domain - - - 0.000000000000000000000000000001357 123.0
HKD1_k127_5296041_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 471.0
HKD1_k127_5296041_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 431.0
HKD1_k127_5296041_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000001336 261.0
HKD1_k127_5296041_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000006136 193.0
HKD1_k127_5296041_4 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000007716 165.0
HKD1_k127_5296041_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000005781 115.0
HKD1_k127_5296041_6 Protein of unknown function (DUF507) - - - 0.000000000000000000000000006229 114.0
HKD1_k127_5296041_7 Protein of unknown function (DUF507) - - - 0.00000000000000000000000001207 112.0
HKD1_k127_5296041_8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000001796 104.0
HKD1_k127_5306226_0 PFAM Polysulphide reductase, NrfD K00185 - - 6.26e-234 740.0
HKD1_k127_5306226_1 PFAM 4Fe-4S K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 443.0
HKD1_k127_5306226_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000004068 177.0
HKD1_k127_5306226_3 lyase activity - - - 0.000000000000000003647 94.0
HKD1_k127_5306226_4 Hemerythrin HHE cation binding domain - - - 0.000000004404 60.0
HKD1_k127_5329019_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 536.0
HKD1_k127_5329019_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 329.0
HKD1_k127_5329019_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 302.0
HKD1_k127_5329019_3 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006541 232.0
HKD1_k127_5329019_4 6-carboxyhexanoate-CoA ligase activity K00652,K01906 - 2.3.1.47,6.2.1.14 0.0000000000000000000000000000000000000000000000000004344 194.0
HKD1_k127_5329019_5 radical SAM domain protein - - - 0.000000000000000000000000000000003315 140.0
HKD1_k127_5329019_6 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02243,K02652 - - 0.00000000000000000000000002038 117.0
HKD1_k127_5329019_7 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000003436 109.0
HKD1_k127_5370493_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0 1232.0
HKD1_k127_5370493_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 289.0
HKD1_k127_5370493_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000044 194.0
HKD1_k127_5370493_3 MGS-like domain - - - 0.0000000000000000000000000000000000000000000002232 176.0
HKD1_k127_5370493_4 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000001807 153.0
HKD1_k127_5370493_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000001021 123.0
HKD1_k127_5370493_6 - - - - 0.0000000000000000000001228 104.0
HKD1_k127_5370493_7 Acetyltransferase (GNAT) domain - - - 0.00000000000004797 79.0
HKD1_k127_5370493_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000005811 60.0
HKD1_k127_5393154_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 616.0
HKD1_k127_5393154_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 405.0
HKD1_k127_5393154_10 - - - - 0.000008977 56.0
HKD1_k127_5393154_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 317.0
HKD1_k127_5393154_3 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001018 264.0
HKD1_k127_5393154_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000001789 263.0
HKD1_k127_5393154_5 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000000000000000000000000000000000000003365 198.0
HKD1_k127_5393154_6 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000002241 125.0
HKD1_k127_5393154_7 - - - - 0.0000000000000000000003648 101.0
HKD1_k127_5410919_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 8.386e-198 625.0
HKD1_k127_5410919_1 ABC transporter transmembrane region K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 486.0
HKD1_k127_5410919_2 Cys Met metabolism K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 384.0
HKD1_k127_5410919_3 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002213 284.0
HKD1_k127_5410919_4 Putative beta-barrel porin 2 K20920 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008933 261.0
HKD1_k127_5410919_5 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000001266 203.0
HKD1_k127_5410919_6 - - - - 0.00000000000000000000003483 110.0
HKD1_k127_5410919_7 Belongs to the peptidase S26 family - - - 0.00000001765 61.0
HKD1_k127_5410919_8 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0002115 47.0
HKD1_k127_5413811_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335,K03469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7,3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 515.0
HKD1_k127_5413811_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 454.0
HKD1_k127_5413811_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 380.0
HKD1_k127_5413811_3 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 304.0
HKD1_k127_5413811_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000001115 237.0
HKD1_k127_5413811_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000007282 168.0
HKD1_k127_5413811_7 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000001026 120.0
HKD1_k127_5413811_9 Domain of unknown function (DUF4912) K09942 - - 0.000001449 58.0
HKD1_k127_5542000_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 528.0
HKD1_k127_5542000_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 486.0
HKD1_k127_5542000_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 335.0
HKD1_k127_5542000_3 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 291.0
HKD1_k127_5542000_4 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000004638 250.0
HKD1_k127_5542000_5 Chemotaxis sensory transducer K03406 - - 0.00007828 46.0
HKD1_k127_5615413_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 5.61e-309 954.0
HKD1_k127_5615413_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.744e-246 770.0
HKD1_k127_5615413_10 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000002147 187.0
HKD1_k127_5615413_11 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000008227 173.0
HKD1_k127_5615413_12 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000868 159.0
HKD1_k127_5615413_13 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000006782 114.0
HKD1_k127_5615413_14 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000001095 87.0
HKD1_k127_5615413_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 606.0
HKD1_k127_5615413_3 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 488.0
HKD1_k127_5615413_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 424.0
HKD1_k127_5615413_5 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 369.0
HKD1_k127_5615413_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000004323 262.0
HKD1_k127_5615413_7 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000004692 254.0
HKD1_k127_5615413_8 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001335 239.0
HKD1_k127_5615413_9 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000002922 226.0
HKD1_k127_568308_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 3.992e-271 846.0
HKD1_k127_568308_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.351e-218 683.0
HKD1_k127_568308_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 406.0
HKD1_k127_568308_11 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 378.0
HKD1_k127_568308_12 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 330.0
HKD1_k127_568308_13 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 315.0
HKD1_k127_568308_14 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 308.0
HKD1_k127_568308_15 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 302.0
HKD1_k127_568308_16 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000004135 244.0
HKD1_k127_568308_17 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000001461 237.0
HKD1_k127_568308_18 ACT domain - - - 0.00000000000000000000000000000000000000000000000000000000005923 207.0
HKD1_k127_568308_19 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000013 204.0
HKD1_k127_568308_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 9.909e-214 670.0
HKD1_k127_568308_20 retrograde transport, endosome to Golgi K07095 - - 0.00000000000000000000000000000000000000000000000000008623 190.0
HKD1_k127_568308_21 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000004545 176.0
HKD1_k127_568308_22 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000001354 169.0
HKD1_k127_568308_23 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000000001728 147.0
HKD1_k127_568308_24 Protein of unknown function (DUF559) - - - 0.00000000000000000000000000000000000004117 147.0
HKD1_k127_568308_25 Cupin domain - - - 0.0000000000000000000000000000000003443 136.0
HKD1_k127_568308_26 4Fe-4S binding domain - - - 0.000000000000000000000000000000007905 129.0
HKD1_k127_568308_27 DNA restriction-modification system - - - 0.000000000000000000000000000001865 128.0
HKD1_k127_568308_28 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000001932 78.0
HKD1_k127_568308_3 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 534.0
HKD1_k127_568308_30 Eco57I restriction-modification methylase - - - 0.00000001881 57.0
HKD1_k127_568308_31 Protein of unknown function (DUF3568) - - - 0.0000003115 62.0
HKD1_k127_568308_4 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 503.0
HKD1_k127_568308_5 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 471.0
HKD1_k127_568308_6 Sodium/hydrogen exchanger family K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 447.0
HKD1_k127_568308_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 453.0
HKD1_k127_568308_8 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 428.0
HKD1_k127_568308_9 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 409.0
HKD1_k127_5687079_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 1.246e-271 858.0
HKD1_k127_5687079_1 amino acid - - - 2.158e-200 641.0
HKD1_k127_5687079_10 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 392.0
HKD1_k127_5687079_11 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 384.0
HKD1_k127_5687079_12 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 372.0
HKD1_k127_5687079_13 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 370.0
HKD1_k127_5687079_14 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 358.0
HKD1_k127_5687079_15 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 343.0
HKD1_k127_5687079_16 Radical SAM superfamily K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 332.0
HKD1_k127_5687079_17 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 327.0
HKD1_k127_5687079_18 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 331.0
HKD1_k127_5687079_19 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 333.0
HKD1_k127_5687079_2 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 610.0
HKD1_k127_5687079_20 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 312.0
HKD1_k127_5687079_21 Receptor K02014,K16087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 302.0
HKD1_k127_5687079_22 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 308.0
HKD1_k127_5687079_23 Histidine kinase K07642,K18143 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000009544 267.0
HKD1_k127_5687079_24 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000003603 260.0
HKD1_k127_5687079_25 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003713 247.0
HKD1_k127_5687079_26 phosphatidate phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000002248 239.0
HKD1_k127_5687079_27 PFAM ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000001197 228.0
HKD1_k127_5687079_28 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000007094 228.0
HKD1_k127_5687079_29 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000003596 227.0
HKD1_k127_5687079_3 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 568.0
HKD1_k127_5687079_30 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000000002666 182.0
HKD1_k127_5687079_31 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000001533 179.0
HKD1_k127_5687079_32 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000155 141.0
HKD1_k127_5687079_33 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000005402 132.0
HKD1_k127_5687079_34 RNA-binding protein containing a PIN domain K06962 - - 0.000000000000000000000000000005763 126.0
HKD1_k127_5687079_35 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.000000000000000000000000000006413 129.0
HKD1_k127_5687079_36 SMART Cold shock protein K03704 - - 0.000000000000000000000000004188 111.0
HKD1_k127_5687079_37 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000206 114.0
HKD1_k127_5687079_38 RNA recognition motif - - - 0.000000000000000000000002609 105.0
HKD1_k127_5687079_39 Cadherin repeats. - - - 0.000000000000000000000006933 117.0
HKD1_k127_5687079_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 536.0
HKD1_k127_5687079_40 domain protein - - - 0.0000000000000000000009802 111.0
HKD1_k127_5687079_41 Belongs to the UPF0235 family K09131 - - 0.0000000000000000001468 91.0
HKD1_k127_5687079_42 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.00000000002352 66.0
HKD1_k127_5687079_43 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000957 67.0
HKD1_k127_5687079_44 Collagen triple helix repeat (20 copies) - - - 0.00000001114 65.0
HKD1_k127_5687079_45 Evidence 5 No homology to any previously reported sequences - - - 0.000001602 58.0
HKD1_k127_5687079_46 - - - - 0.000004514 51.0
HKD1_k127_5687079_6 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 460.0
HKD1_k127_5687079_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 447.0
HKD1_k127_5687079_8 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 420.0
HKD1_k127_5687079_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 402.0
HKD1_k127_575879_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.326e-254 790.0
HKD1_k127_575879_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 365.0
HKD1_k127_575879_2 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009801 340.0
HKD1_k127_575879_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 336.0
HKD1_k127_575879_4 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.00000000000001036 75.0
HKD1_k127_575879_5 FixH - - - 0.000000002046 64.0
HKD1_k127_5838622_0 Aminotransferase class I and II K14261 - - 5.532e-209 655.0
HKD1_k127_5838622_1 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 357.0
HKD1_k127_5838622_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 330.0
HKD1_k127_5838622_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 320.0
HKD1_k127_5838622_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 312.0
HKD1_k127_5838622_5 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000005542 223.0
HKD1_k127_5838622_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000001706 196.0
HKD1_k127_5838622_7 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000816 181.0
HKD1_k127_5838622_8 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000008736 104.0
HKD1_k127_5838622_9 competence protein - - - 0.0000001813 63.0
HKD1_k127_5871961_0 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 564.0
HKD1_k127_5871961_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 372.0
HKD1_k127_5871961_2 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 301.0
HKD1_k127_5871961_3 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000004771 237.0
HKD1_k127_5871961_4 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000007345 231.0
HKD1_k127_5871961_5 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000001281 139.0
HKD1_k127_5871961_6 HD domain K07023 - - 0.000000000000000000000002232 102.0
HKD1_k127_5871961_7 electron transfer activity K05337,K17247 - - 0.000000000000000003588 85.0
HKD1_k127_5871961_8 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.0000000000001994 72.0
HKD1_k127_5871961_9 SEC-C Motif Domain Protein - - - 0.00000000009672 70.0
HKD1_k127_5972229_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 530.0
HKD1_k127_5972229_1 Indole-3-glycerol phosphate synthase K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000007639 234.0
HKD1_k127_5972229_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000005372 222.0
HKD1_k127_5972229_3 Universal stress protein family - - - 0.000000000000000000000000000000000001572 141.0
HKD1_k127_5972229_4 energy transducer activity K03832 - - 0.0000000000000000000000000000000013 140.0
HKD1_k127_5972229_5 proteolysis K03665 - - 0.000000000000000000000000005226 117.0
HKD1_k127_5972229_6 - - - - 0.000000000001975 67.0
HKD1_k127_599584_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 378.0
HKD1_k127_599584_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 300.0
HKD1_k127_599584_2 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000001026 216.0
HKD1_k127_599584_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000003604 194.0
HKD1_k127_599584_4 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000005151 150.0
HKD1_k127_599584_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0003341 44.0
HKD1_k127_601625_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 525.0
HKD1_k127_601625_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 503.0
HKD1_k127_601625_10 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000008388 172.0
HKD1_k127_601625_11 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000004723 159.0
HKD1_k127_601625_12 Transcriptional regulator - - - 0.00000000000000000000000000000000000003271 148.0
HKD1_k127_601625_13 Sulfurtransferase TusA - - - 0.0000000000000000000000767 101.0
HKD1_k127_601625_14 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000009463 92.0
HKD1_k127_601625_2 Protein of unknown function (DUF3141) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 456.0
HKD1_k127_601625_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 410.0
HKD1_k127_601625_4 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 376.0
HKD1_k127_601625_5 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 355.0
HKD1_k127_601625_6 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000326 220.0
HKD1_k127_601625_7 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000009688 204.0
HKD1_k127_601625_8 FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000000000000000000000000004862 202.0
HKD1_k127_601625_9 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000000000000000000000000000000000005751 179.0
HKD1_k127_6048281_0 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 397.0
HKD1_k127_6048281_1 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 388.0
HKD1_k127_6048281_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003274 271.0
HKD1_k127_6048281_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004487 258.0
HKD1_k127_6048281_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000001912 235.0
HKD1_k127_6048281_5 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000003983 142.0
HKD1_k127_6074229_0 epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 551.0
HKD1_k127_6074229_1 ADP-glyceromanno-heptose 6-epimerase activity K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 539.0
HKD1_k127_6074229_2 PFAM ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001523 261.0
HKD1_k127_6074229_3 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000497 243.0
HKD1_k127_6074229_4 PFAM PHP domain protein K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000005125 179.0
HKD1_k127_6074229_5 KOW (Kyprides, Ouzounis, Woese) motif. K05785 - - 0.0000000000000000000000000000003014 128.0
HKD1_k127_6074229_6 DNA-binding transcription factor activity K18996 - - 0.0000000000000000000000003371 108.0
HKD1_k127_6151517_0 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 565.0
HKD1_k127_6151517_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 556.0
HKD1_k127_6151517_2 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 403.0
HKD1_k127_6151517_3 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007598 398.0
HKD1_k127_6151517_4 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 366.0
HKD1_k127_6151517_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001761 260.0
HKD1_k127_6151517_6 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000007328 195.0
HKD1_k127_6151517_7 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000113 144.0
HKD1_k127_6151517_8 Response regulator receiver K01338 - 3.4.21.53 0.000000000000003157 80.0
HKD1_k127_6164365_0 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0 1217.0
HKD1_k127_6164365_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1018.0
HKD1_k127_6164365_10 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 318.0
HKD1_k127_6164365_11 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 313.0
HKD1_k127_6164365_12 PFAM thiamine pyrophosphate protein domain protein TPP-binding K09459 - 4.1.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 308.0
HKD1_k127_6164365_13 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009557 289.0
HKD1_k127_6164365_14 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006392 278.0
HKD1_k127_6164365_15 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004742 258.0
HKD1_k127_6164365_16 peptidyl-prolyl cis-trans isomerase activity K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000009684 199.0
HKD1_k127_6164365_17 TIGRFAM iron-sulfur cluster binding protein - - - 0.00000000000000000000000000000000000000000000000004602 185.0
HKD1_k127_6164365_18 PFAM Carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000000000003537 160.0
HKD1_k127_6164365_19 diguanylate cyclase - - - 0.000000000000000000000000000000000000001588 167.0
HKD1_k127_6164365_2 alpha amylase, catalytic K01236 - 3.2.1.141 2.495e-235 744.0
HKD1_k127_6164365_20 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000004407 133.0
HKD1_k127_6164365_21 OsmC-like protein - - - 0.0000000000000000000000002813 112.0
HKD1_k127_6164365_22 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000001855 104.0
HKD1_k127_6164365_23 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000001484 106.0
HKD1_k127_6164365_24 - - - - 0.0000000000000007507 81.0
HKD1_k127_6164365_25 Fe-S oxidoreductase - - - 0.0000000002887 70.0
HKD1_k127_6164365_26 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 0.0005687 47.0
HKD1_k127_6164365_3 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 6.658e-234 740.0
HKD1_k127_6164365_4 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 3.044e-196 620.0
HKD1_k127_6164365_5 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 422.0
HKD1_k127_6164365_6 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 376.0
HKD1_k127_6164365_7 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 358.0
HKD1_k127_6164365_8 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 333.0
HKD1_k127_6164365_9 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 318.0
HKD1_k127_6168388_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.348e-217 679.0
HKD1_k127_6168388_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 634.0
HKD1_k127_6168388_10 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000001026 178.0
HKD1_k127_6168388_11 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000004696 161.0
HKD1_k127_6168388_12 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000001097 144.0
HKD1_k127_6168388_13 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000002211 135.0
HKD1_k127_6168388_14 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000423 126.0
HKD1_k127_6168388_15 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000002783 133.0
HKD1_k127_6168388_16 Ribosomal protein L36 K02919 - - 0.0000000000000008574 77.0
HKD1_k127_6168388_17 ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000007641 74.0
HKD1_k127_6168388_2 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 437.0
HKD1_k127_6168388_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 360.0
HKD1_k127_6168388_4 Psort location Cytoplasmic, score K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 317.0
HKD1_k127_6168388_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007262 277.0
HKD1_k127_6168388_6 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001643 246.0
HKD1_k127_6168388_7 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000254 215.0
HKD1_k127_6168388_8 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000005708 206.0
HKD1_k127_6168388_9 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000006474 180.0
HKD1_k127_6179037_0 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 1.13e-241 782.0
HKD1_k127_6179037_1 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 362.0
HKD1_k127_6179037_2 Type IV pilin-like G and H, putative K02650 - - 0.000000001545 65.0
HKD1_k127_6179037_3 Cell motility and secretion Intracellular trafficking and secretion - - - 0.00000009861 61.0
HKD1_k127_6181119_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.402e-258 809.0
HKD1_k127_6181119_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 296.0
HKD1_k127_6181119_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 291.0
HKD1_k127_6181119_3 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000003362 188.0
HKD1_k127_6201673_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001703 254.0
HKD1_k127_6201673_1 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000002942 193.0
HKD1_k127_6201673_10 Phosphoesterase family - - - 0.000001287 60.0
HKD1_k127_6201673_11 cellulose binding - - - 0.00008852 54.0
HKD1_k127_6201673_2 Helix-hairpin-helix motif - - - 0.0000000000000000000000000000000000000000000000001623 184.0
HKD1_k127_6201673_3 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000003296 172.0
HKD1_k127_6201673_4 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000001647 168.0
HKD1_k127_6201673_5 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000000000004279 158.0
HKD1_k127_6201673_6 PFAM Nitroreductase family - - - 0.000000000000000000000000000000000005461 149.0
HKD1_k127_6201673_7 - - - - 0.000000000000000000000000000002059 123.0
HKD1_k127_6201673_9 Glycosyl transferase family 41 - - - 0.000000000002294 75.0
HKD1_k127_6224414_0 domain, Protein K01176,K03332 - 3.2.1.1,3.2.1.80 2.156e-237 758.0
HKD1_k127_6224414_1 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 522.0
HKD1_k127_6224414_10 Protein of unknown function (DUF2844) - - - 0.000000000000000000000000000000000000000000000005112 177.0
HKD1_k127_6224414_11 SMART PDZ DHR GLGF domain protein K02452 - - 0.00000000000000000000000000000000000000000004614 171.0
HKD1_k127_6224414_12 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.0000000000000000000000000000001698 128.0
HKD1_k127_6224414_13 Putative methyltransferase - - - 0.00000000000000001519 96.0
HKD1_k127_6224414_14 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000008278 48.0
HKD1_k127_6224414_2 Protein of unknown function (DUF3443) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 457.0
HKD1_k127_6224414_3 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 416.0
HKD1_k127_6224414_4 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 403.0
HKD1_k127_6224414_5 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009375 360.0
HKD1_k127_6224414_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 321.0
HKD1_k127_6224414_7 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 304.0
HKD1_k127_6224414_8 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000192 275.0
HKD1_k127_6224414_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007493 276.0
HKD1_k127_6245189_0 FAD binding domain K00394 - 1.8.99.2 0.0 1069.0
HKD1_k127_6245189_1 Methyl-viologen-reducing hydrogenase, delta subunit K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4.45e-322 1002.0
HKD1_k127_6245189_2 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 587.0
HKD1_k127_6245189_3 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 533.0
HKD1_k127_6245189_4 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003169 281.0
HKD1_k127_6245189_5 reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000003454 248.0
HKD1_k127_6290152_0 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 519.0
HKD1_k127_6290152_1 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 487.0
HKD1_k127_6290152_10 - - - - 0.0000000001335 64.0
HKD1_k127_6290152_11 PilZ domain - - - 0.0000005956 57.0
HKD1_k127_6290152_12 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051082,GO:0061077,GO:1990507 - 0.000003354 55.0
HKD1_k127_6290152_13 GYD domain - - - 0.0001318 46.0
HKD1_k127_6290152_2 PHB de-polymerase C-terminus K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 440.0
HKD1_k127_6290152_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 413.0
HKD1_k127_6290152_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001049 247.0
HKD1_k127_6290152_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000753 158.0
HKD1_k127_6290152_6 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.000000000000000000000000174 119.0
HKD1_k127_6290152_7 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000000000000000004061 112.0
HKD1_k127_6290152_8 - - - - 0.0000000000000000000008426 104.0
HKD1_k127_6290152_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000001811 72.0
HKD1_k127_6294259_0 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000001722 123.0
HKD1_k127_6294259_1 Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB K02014,K16092 - - 0.000000000000000000000000001218 121.0
HKD1_k127_6294259_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000002231 85.0
HKD1_k127_6294259_3 DsrE/DsrF-like family K07235 - - 0.00000000000379 72.0
HKD1_k127_6294259_4 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000005126 66.0
HKD1_k127_6294259_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000005593 66.0
HKD1_k127_6294259_6 COG3086 Positive regulator of sigma E activity K03803 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000002355 56.0
HKD1_k127_6318601_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 564.0
HKD1_k127_6318601_1 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 308.0
HKD1_k127_6318601_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000351 215.0
HKD1_k127_6318601_3 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000008459 116.0
HKD1_k127_6318601_4 PFAM PQ loop repeat K15383 - - 0.000000000000000000000004627 106.0
HKD1_k127_6318601_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000001364 62.0
HKD1_k127_6318601_6 Scaffold protein Nfu/NifU N terminal - - - 0.000105 50.0
HKD1_k127_6326822_0 Nitrate nitrite transporter K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 565.0
HKD1_k127_6326822_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 379.0
HKD1_k127_6326822_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000008627 117.0
HKD1_k127_6326822_3 cytochrome c - - - 0.0000002482 55.0
HKD1_k127_6347246_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 7.984e-317 994.0
HKD1_k127_6347246_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 5.14e-219 694.0
HKD1_k127_6347246_10 - - - - 0.0006269 47.0
HKD1_k127_6347246_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009974 540.0
HKD1_k127_6347246_3 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000984 405.0
HKD1_k127_6347246_4 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 407.0
HKD1_k127_6347246_5 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 361.0
HKD1_k127_6347246_6 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000001029 235.0
HKD1_k127_6347246_7 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000002769 162.0
HKD1_k127_6347246_8 - - - - 0.00000000003003 72.0
HKD1_k127_6347246_9 cell adhesion K02650,K02682 - - 0.00000001039 63.0
HKD1_k127_6347251_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 494.0
HKD1_k127_6347251_1 HD domain - - - 0.000000000000000000005007 104.0
HKD1_k127_637628_0 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 526.0
HKD1_k127_637628_1 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 504.0
HKD1_k127_637628_10 methyltransferase activity - - - 0.0000000000000000000000000000000000000248 152.0
HKD1_k127_637628_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.0000000000000000000000000000009457 127.0
HKD1_k127_637628_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000001341 126.0
HKD1_k127_637628_13 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000009989 110.0
HKD1_k127_637628_14 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000001563 99.0
HKD1_k127_637628_15 4Fe-4S binding domain K00338 - 1.6.5.3 0.000000000000000001269 96.0
HKD1_k127_637628_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000002712 92.0
HKD1_k127_637628_17 Chlorophyllase - - - 0.00004529 55.0
HKD1_k127_637628_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 457.0
HKD1_k127_637628_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 433.0
HKD1_k127_637628_4 Nadph-dependent fmn reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 374.0
HKD1_k127_637628_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 367.0
HKD1_k127_637628_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 367.0
HKD1_k127_637628_7 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 293.0
HKD1_k127_637628_8 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004882 263.0
HKD1_k127_637628_9 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000001365 222.0
HKD1_k127_6417607_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.019e-292 907.0
HKD1_k127_6417607_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 338.0
HKD1_k127_6417607_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 327.0
HKD1_k127_6417607_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 312.0
HKD1_k127_6417607_4 Gaf domain K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000005316 179.0
HKD1_k127_6417607_5 - K07112 - - 0.000000000000000000000000000000000000001112 153.0
HKD1_k127_6417607_6 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000002716 88.0
HKD1_k127_6417607_7 Sporulation and spore germination - - - 0.0000000000005261 77.0
HKD1_k127_6422885_0 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 600.0
HKD1_k127_6422885_1 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 548.0
HKD1_k127_6422885_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000005619 168.0
HKD1_k127_6422885_11 GGDEF domain - - - 0.000000000000000003991 94.0
HKD1_k127_6422885_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 443.0
HKD1_k127_6422885_3 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 441.0
HKD1_k127_6422885_4 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001259 292.0
HKD1_k127_6422885_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003025 284.0
HKD1_k127_6422885_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001752 268.0
HKD1_k127_6422885_7 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000001721 233.0
HKD1_k127_6422885_8 - - - - 0.0000000000000000000000000000000000000000000000000000000003321 213.0
HKD1_k127_6422885_9 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000002438 175.0
HKD1_k127_6444140_0 FecR protein - - - 0.0 1146.0
HKD1_k127_6444140_1 glucan 1,4-alpha-glucosidase activity - - - 5.165e-235 744.0
HKD1_k127_6444140_10 nucleoside hydrolase - - - 0.000000000000449 83.0
HKD1_k127_6444140_11 - - - - 0.0000001343 59.0
HKD1_k127_6444140_2 CHASE2 K01768 - 4.6.1.1 8.301e-231 736.0
HKD1_k127_6444140_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 334.0
HKD1_k127_6444140_4 Oxidoreductase molybdopterin binding domain K00387,K07147 - 1.8.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005363 287.0
HKD1_k127_6444140_5 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001015 267.0
HKD1_k127_6444140_6 Yhs domain-containing protein - - - 0.000000000000000000000000000000000000000008459 160.0
HKD1_k127_6444140_7 Cytochrome c K08906,K12263 - - 0.000000000000000000001165 98.0
HKD1_k127_6444140_8 PFAM response regulator receiver K03413 - - 0.000000000000000005932 89.0
HKD1_k127_6444140_9 PFAM Methylamine - - - 0.000000000000008271 80.0
HKD1_k127_6445393_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 310.0
HKD1_k127_6445393_1 SMART Signal transduction response regulator, receiver region - - - 0.00000000000000000000000000000000000000000000000000000000000005682 216.0
HKD1_k127_6445393_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000002249 216.0
HKD1_k127_6445393_3 Histidine kinase K07711 - 2.7.13.3 0.000000000000000000000000000000000000005906 162.0
HKD1_k127_6445393_4 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000001106 151.0
HKD1_k127_6445393_5 Histidine kinase - - - 0.000000000000000000000000000000000003299 153.0
HKD1_k127_6445393_6 PAS domain - - - 0.00000000000000000000000000000000004852 152.0
HKD1_k127_6448384_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1199.0
HKD1_k127_6448384_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1127.0
HKD1_k127_6448384_10 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 426.0
HKD1_k127_6448384_11 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 421.0
HKD1_k127_6448384_12 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 401.0
HKD1_k127_6448384_13 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 379.0
HKD1_k127_6448384_14 Family 5 K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 361.0
HKD1_k127_6448384_15 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 346.0
HKD1_k127_6448384_16 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 346.0
HKD1_k127_6448384_17 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 327.0
HKD1_k127_6448384_18 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 334.0
HKD1_k127_6448384_19 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 336.0
HKD1_k127_6448384_2 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1124.0
HKD1_k127_6448384_20 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 316.0
HKD1_k127_6448384_21 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 309.0
HKD1_k127_6448384_22 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 299.0
HKD1_k127_6448384_23 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 297.0
HKD1_k127_6448384_24 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 295.0
HKD1_k127_6448384_25 4Fe-4S ferredoxin K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 295.0
HKD1_k127_6448384_26 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 288.0
HKD1_k127_6448384_27 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 301.0
HKD1_k127_6448384_28 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 291.0
HKD1_k127_6448384_29 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000049 284.0
HKD1_k127_6448384_3 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1105.0
HKD1_k127_6448384_30 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000129 282.0
HKD1_k127_6448384_31 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003315 278.0
HKD1_k127_6448384_32 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005249 284.0
HKD1_k127_6448384_33 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000001574 263.0
HKD1_k127_6448384_34 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000001504 252.0
HKD1_k127_6448384_35 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000001619 229.0
HKD1_k127_6448384_36 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000004242 243.0
HKD1_k127_6448384_37 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000132 227.0
HKD1_k127_6448384_38 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000001908 221.0
HKD1_k127_6448384_39 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.00000000000000000000000000000000000000000000000000000000001523 211.0
HKD1_k127_6448384_4 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1063.0
HKD1_k127_6448384_40 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000008856 207.0
HKD1_k127_6448384_41 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000002176 205.0
HKD1_k127_6448384_42 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000002084 212.0
HKD1_k127_6448384_43 Polysulfide reductase - - - 0.0000000000000000000000000000000000000000000000000000827 198.0
HKD1_k127_6448384_44 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000000004648 183.0
HKD1_k127_6448384_46 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000009095 187.0
HKD1_k127_6448384_47 iron ion homeostasis K03709,K04758 - - 0.00000000000000000000000000000000000000000000000002591 190.0
HKD1_k127_6448384_48 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000001018 174.0
HKD1_k127_6448384_49 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000002542 162.0
HKD1_k127_6448384_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 608.0
HKD1_k127_6448384_50 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000004868 151.0
HKD1_k127_6448384_51 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000009405 156.0
HKD1_k127_6448384_52 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000003518 147.0
HKD1_k127_6448384_53 Peptidase C26 K07010 - - 0.000000000000000000000000000000000001898 147.0
HKD1_k127_6448384_54 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000002331 146.0
HKD1_k127_6448384_55 Protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000000001337 147.0
HKD1_k127_6448384_56 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000001086 130.0
HKD1_k127_6448384_57 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000000009564 122.0
HKD1_k127_6448384_58 cell redox homeostasis K02199 - - 0.0000000000000000000000000002477 122.0
HKD1_k127_6448384_59 Polymer-forming cytoskeletal - - - 0.000000000000000000000000001787 115.0
HKD1_k127_6448384_6 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 597.0
HKD1_k127_6448384_60 Ribosomal protein S16 K02959 - - 0.0000000000000000000000001542 107.0
HKD1_k127_6448384_61 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000009286 117.0
HKD1_k127_6448384_62 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000002146 109.0
HKD1_k127_6448384_63 PFAM Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000000006 108.0
HKD1_k127_6448384_65 Protein of unknown function (DUF2905) - - - 0.00000000000000000136 90.0
HKD1_k127_6448384_66 - - - - 0.0000000000000001203 82.0
HKD1_k127_6448384_68 protein secretion K03116,K03117 - - 0.0000000000001043 74.0
HKD1_k127_6448384_69 Diguanylate cyclase - - - 0.00000000003478 72.0
HKD1_k127_6448384_7 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 583.0
HKD1_k127_6448384_70 - - - - 0.0002151 49.0
HKD1_k127_6448384_8 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 524.0
HKD1_k127_6448384_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 477.0
HKD1_k127_6453372_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1433.0
HKD1_k127_6453372_1 Glycogen debranching enzyme - - - 2.639e-250 778.0
HKD1_k127_6453372_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 5.284e-207 654.0
HKD1_k127_6453372_3 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 460.0
HKD1_k127_6453372_4 Carbohydrate-selective porin, OprB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003273 258.0
HKD1_k127_6493701_0 PFAM Radical SAM - - - 1.29e-207 658.0
HKD1_k127_6493701_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 554.0
HKD1_k127_6493701_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000004767 240.0
HKD1_k127_6493701_3 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000005323 242.0
HKD1_k127_6493701_4 endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000003238 162.0
HKD1_k127_6493701_5 metallopeptidase activity K01387,K01730,K20276 - 3.4.24.3,4.2.2.6 0.000000000000000000000000000000000000000003379 179.0
HKD1_k127_6493701_6 cellulase activity K01387 - 3.4.24.3 0.0000000000000257 87.0
HKD1_k127_6493701_7 COG NOG04032 non supervised orthologous group K17624 - 3.2.1.97 0.000000003696 70.0
HKD1_k127_6590740_0 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 605.0
HKD1_k127_6590740_1 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 331.0
HKD1_k127_6590740_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 330.0
HKD1_k127_6590740_3 PFAM PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008546 285.0
HKD1_k127_6590740_4 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000002142 220.0
HKD1_k127_6590740_5 cheY-homologous receiver domain - - - 0.000000000000000000000003781 106.0
HKD1_k127_6590740_6 CBS domain K00974 - 2.7.7.72 0.00000000000007797 73.0
HKD1_k127_6590740_7 helix_turn_helix ASNC type K03718 - - 0.00001663 51.0
HKD1_k127_6619278_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 458.0
HKD1_k127_6619278_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005747 271.0
HKD1_k127_6619278_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000004374 233.0
HKD1_k127_6619278_3 DivIVA protein K04074 - - 0.000000000000000000000000000000000000000000000000000000002577 206.0
HKD1_k127_6619278_4 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000001434 123.0
HKD1_k127_6619278_5 membrane - - - 0.00000000000000000000000000007527 128.0
HKD1_k127_6619278_6 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000005413 83.0
HKD1_k127_6619553_0 1,4-alpha-glucan branching enzyme activity K00700,K01187,K01236,K17734 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,3.2.1.141,3.2.1.20 3.596e-221 692.0
HKD1_k127_6619553_1 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 552.0
HKD1_k127_6619553_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 331.0
HKD1_k127_6619553_3 queuosine metabolic process K04068,K10026 - 1.97.1.4,4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000004923 231.0
HKD1_k127_6619553_4 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000002402 213.0
HKD1_k127_6619553_5 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000001963 208.0
HKD1_k127_6637408_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.343e-258 807.0
HKD1_k127_6637408_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.22e-199 626.0
HKD1_k127_6637408_10 HD domain - - - 0.0000000000000000000000000000000000009994 151.0
HKD1_k127_6637408_2 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 398.0
HKD1_k127_6637408_3 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 358.0
HKD1_k127_6637408_4 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 347.0
HKD1_k127_6637408_5 Peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 352.0
HKD1_k127_6637408_6 Electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002811 284.0
HKD1_k127_6637408_7 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000004493 232.0
HKD1_k127_6637408_8 B12 binding domain K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000009731 181.0
HKD1_k127_6637408_9 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000006054 155.0
HKD1_k127_6638416_0 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 297.0
HKD1_k127_6638416_1 Glycosyl transferase, family 2 K12992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 293.0
HKD1_k127_6638416_2 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000001915 205.0
HKD1_k127_6638416_3 DEAD DEAH box helicase K06877 - - 0.00000000000000000000000000000000000000000000000000004069 192.0
HKD1_k127_6638416_4 Sulfotransferase family - - - 0.000000000000000000002942 109.0
HKD1_k127_6638416_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000002542 103.0
HKD1_k127_6646293_0 membrane - - - 1.15e-253 795.0
HKD1_k127_6646293_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 9.981e-234 730.0
HKD1_k127_6646293_10 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000003871 68.0
HKD1_k127_6646293_12 - K06039,K07092 - - 0.0000001919 57.0
HKD1_k127_6646293_2 GAF domain K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 559.0
HKD1_k127_6646293_3 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 495.0
HKD1_k127_6646293_4 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 342.0
HKD1_k127_6646293_5 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000001415 213.0
HKD1_k127_6646293_6 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000006555 193.0
HKD1_k127_6646293_7 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein - - - 0.00000000000000000000000000000000000000139 154.0
HKD1_k127_6646293_8 Protein of unknown function DUF134 - - - 0.0000000000000000000000000181 111.0
HKD1_k127_6646293_9 - - - - 0.0000000000000000004306 91.0
HKD1_k127_6659001_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 629.0
HKD1_k127_6659001_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 443.0
HKD1_k127_6659001_10 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000000003272 203.0
HKD1_k127_6659001_11 Efflux ABC transporter, permease protein K02004 - - 0.000000000000000000000000000000000000000000000289 182.0
HKD1_k127_6659001_12 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000000000000000000000002689 176.0
HKD1_k127_6659001_14 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000009194 74.0
HKD1_k127_6659001_2 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 411.0
HKD1_k127_6659001_3 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 382.0
HKD1_k127_6659001_4 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 361.0
HKD1_k127_6659001_5 ABC transporter, permease protein K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 334.0
HKD1_k127_6659001_6 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 312.0
HKD1_k127_6659001_7 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006683 289.0
HKD1_k127_6659001_8 abc transporter atp-binding protein K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006868 267.0
HKD1_k127_6659001_9 SIS domain K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000001 212.0
HKD1_k127_6714683_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.924e-209 661.0
HKD1_k127_6714683_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 503.0
HKD1_k127_6714683_2 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 284.0
HKD1_k127_6714683_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000005409 187.0
HKD1_k127_6717694_0 Telomere recombination K04656 - - 4.053e-240 764.0
HKD1_k127_6717694_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 4.79e-226 737.0
HKD1_k127_6717694_10 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 325.0
HKD1_k127_6717694_11 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 312.0
HKD1_k127_6717694_12 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000007367 232.0
HKD1_k127_6717694_13 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000001043 229.0
HKD1_k127_6717694_14 Hit family K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000001444 205.0
HKD1_k127_6717694_15 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000002051 201.0
HKD1_k127_6717694_16 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000001981 200.0
HKD1_k127_6717694_17 PFAM CBS domain - - - 0.0000000000000000000000000000000000000004138 153.0
HKD1_k127_6717694_18 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000006424 171.0
HKD1_k127_6717694_19 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000001592 143.0
HKD1_k127_6717694_2 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 635.0
HKD1_k127_6717694_20 S-layer homology domain - - - 0.000000000000000000000000000000263 143.0
HKD1_k127_6717694_21 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000002664 124.0
HKD1_k127_6717694_22 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000005335 123.0
HKD1_k127_6717694_23 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000335 122.0
HKD1_k127_6717694_24 - - - - 0.0000000000000000006117 92.0
HKD1_k127_6717694_25 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0000000000000002429 91.0
HKD1_k127_6717694_26 lipopolysaccharide transmembrane transporter activity K03303,K07058 - - 0.000000000119 72.0
HKD1_k127_6717694_27 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.000001052 60.0
HKD1_k127_6717694_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 471.0
HKD1_k127_6717694_4 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 438.0
HKD1_k127_6717694_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K09251 - 2.6.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 432.0
HKD1_k127_6717694_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 398.0
HKD1_k127_6717694_7 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 375.0
HKD1_k127_6717694_8 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 361.0
HKD1_k127_6717694_9 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 317.0
HKD1_k127_6732726_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.25e-322 1003.0
HKD1_k127_6732726_1 COG0058 Glucan phosphorylase - - - 8.333e-253 790.0
HKD1_k127_6732726_10 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000002262 247.0
HKD1_k127_6732726_11 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000003265 219.0
HKD1_k127_6732726_12 shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000001483 174.0
HKD1_k127_6732726_13 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000005009 156.0
HKD1_k127_6732726_14 RDD family - - - 0.000000000000000000000000014 115.0
HKD1_k127_6732726_15 cheY-homologous receiver domain - - - 0.000000000000000001209 90.0
HKD1_k127_6732726_16 exodeoxyribonuclease I activity - - - 0.0000000005909 65.0
HKD1_k127_6732726_17 rod shape-determining protein MreD K03571 - - 0.00001778 53.0
HKD1_k127_6732726_2 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 537.0
HKD1_k127_6732726_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 511.0
HKD1_k127_6732726_4 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 503.0
HKD1_k127_6732726_5 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 444.0
HKD1_k127_6732726_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 426.0
HKD1_k127_6732726_7 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 419.0
HKD1_k127_6732726_8 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005362 287.0
HKD1_k127_6732726_9 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005028 280.0
HKD1_k127_6750615_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.15e-244 768.0
HKD1_k127_6750615_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 406.0
HKD1_k127_6750615_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 402.0
HKD1_k127_6750615_3 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 383.0
HKD1_k127_6750615_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 368.0
HKD1_k127_6750615_5 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004642 275.0
HKD1_k127_6750615_6 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000002373 272.0
HKD1_k127_6750615_7 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000005795 219.0
HKD1_k127_6750615_8 Histidine kinase - - - 0.0000001187 61.0
HKD1_k127_6804362_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 2.22e-287 913.0
HKD1_k127_6804362_1 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 1.253e-209 657.0
HKD1_k127_6804362_10 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 311.0
HKD1_k127_6804362_11 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000002131 239.0
HKD1_k127_6804362_12 PFAM phosphoesterase RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003086 238.0
HKD1_k127_6804362_13 COG0642 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000002101 179.0
HKD1_k127_6804362_14 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000002115 128.0
HKD1_k127_6804362_2 glycosyl transferase family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 596.0
HKD1_k127_6804362_3 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 466.0
HKD1_k127_6804362_4 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 465.0
HKD1_k127_6804362_5 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 432.0
HKD1_k127_6804362_6 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 425.0
HKD1_k127_6804362_7 Binding-protein-dependent transport system inner membrane component K02026,K10238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 348.0
HKD1_k127_6804362_8 ATPases associated with a variety of cellular activities K10112,K10195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 339.0
HKD1_k127_6804362_9 Binding-protein-dependent transport system inner membrane component K02025,K10237,K15771 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 334.0
HKD1_k127_6829315_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1024.0
HKD1_k127_6829315_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 545.0
HKD1_k127_6829315_2 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 534.0
HKD1_k127_6829315_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 371.0
HKD1_k127_6829315_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000002478 153.0
HKD1_k127_6829315_5 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000002139 94.0
HKD1_k127_6829315_6 Type II secretion system protein B K02451 - - 0.0000000000000000004988 96.0
HKD1_k127_684475_0 cell redox homeostasis - - - 5.135e-218 685.0
HKD1_k127_684475_1 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 377.0
HKD1_k127_684475_2 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 334.0
HKD1_k127_684475_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 312.0
HKD1_k127_684475_4 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 307.0
HKD1_k127_684475_5 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000007561 146.0
HKD1_k127_684475_6 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.00000000000000000000000000000000000003555 146.0
HKD1_k127_684475_7 - - - - 0.00000000000000000008875 98.0
HKD1_k127_684475_8 Universal stress protein family - - - 0.0000000000000000007701 97.0
HKD1_k127_6848757_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 3.383e-319 987.0
HKD1_k127_6848757_1 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 1.21e-272 857.0
HKD1_k127_6848757_2 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 490.0
HKD1_k127_6848757_3 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 369.0
HKD1_k127_6848757_4 Predicted membrane protein (DUF2127) - - - 0.000000000000000000000000000000000000000000000000000003041 195.0
HKD1_k127_6848757_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000002349 113.0
HKD1_k127_6848757_6 Ribbon-helix-helix protein, copG family - - - 0.0000000000004592 72.0
HKD1_k127_6863094_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1107.0
HKD1_k127_6863094_1 DNA polymerase K02347 - - 7.78e-212 672.0
HKD1_k127_6863094_11 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000001986 71.0
HKD1_k127_6863094_12 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000007024 63.0
HKD1_k127_6863094_2 Sigma-54 interaction domain K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 436.0
HKD1_k127_6863094_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 379.0
HKD1_k127_6863094_4 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000004519 241.0
HKD1_k127_6863094_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000003339 250.0
HKD1_k127_6863094_6 TIGRFAM molybdenum cofactor synthesis domain - - - 0.000000000000000000000000000000000000000000000000000000000001535 215.0
HKD1_k127_6863094_7 PFAM MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000002885 209.0
HKD1_k127_6863094_8 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000002658 163.0
HKD1_k127_6863094_9 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000009092 125.0
HKD1_k127_6883819_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.385e-272 846.0
HKD1_k127_6883819_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 557.0
HKD1_k127_6883819_10 - - - - 0.000000001044 63.0
HKD1_k127_6883819_11 PFAM type II and III secretion system protein K02666 - - 0.000002502 54.0
HKD1_k127_6883819_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 475.0
HKD1_k127_6883819_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 399.0
HKD1_k127_6883819_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 322.0
HKD1_k127_6883819_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 311.0
HKD1_k127_6883819_6 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001725 282.0
HKD1_k127_6883819_7 - - - - 0.0000000000000000000000000000000000000000000000000000247 197.0
HKD1_k127_6883819_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000001446 134.0
HKD1_k127_6883819_9 Membrane - - - 0.000000000000000000000001518 120.0
HKD1_k127_6978209_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1331.0
HKD1_k127_6978209_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000001481 60.0
HKD1_k127_7067316_0 Bacterial type II and III secretion system protein K02453,K03219 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 315.0
HKD1_k127_7067316_1 group 2 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000001993 226.0
HKD1_k127_7067316_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000008208 115.0
HKD1_k127_7067316_3 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00000003367 59.0
HKD1_k127_7107847_0 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 576.0
HKD1_k127_7107847_1 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 293.0
HKD1_k127_7107847_2 - - - - 0.0005554 52.0
HKD1_k127_7107847_3 ResB-like family K07399 - - 0.0009088 51.0
HKD1_k127_7110675_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.514e-240 755.0
HKD1_k127_7110675_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 435.0
HKD1_k127_7110675_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000005626 231.0
HKD1_k127_7110675_3 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000006664 116.0
HKD1_k127_7119579_0 NADH dehydrogenase - - - 2.745e-221 710.0
HKD1_k127_7119579_1 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000004131 212.0
HKD1_k127_7119579_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.000000000000000000000000000000000000000000000000000003364 196.0
HKD1_k127_7119579_3 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000022 184.0
HKD1_k127_7119579_4 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000008912 135.0
HKD1_k127_7124641_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 2.751e-212 671.0
HKD1_k127_7124641_1 spermidine synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 453.0
HKD1_k127_7124641_10 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000000000002005 204.0
HKD1_k127_7124641_11 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000004134 152.0
HKD1_k127_7124641_12 PFAM Pentapeptide repeats (8 copies) - - - 0.000000000000000000002511 109.0
HKD1_k127_7124641_13 - - - - 0.00000000004039 65.0
HKD1_k127_7124641_14 hydrolase activity, acting on ester bonds - - - 0.000001123 60.0
HKD1_k127_7124641_2 Large family of predicted nucleotide-binding domains K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 384.0
HKD1_k127_7124641_3 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 359.0
HKD1_k127_7124641_4 PFAM Type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 326.0
HKD1_k127_7124641_5 DJ-1/PfpI family K03152 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007233 270.0
HKD1_k127_7124641_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002876 248.0
HKD1_k127_7124641_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000001132 243.0
HKD1_k127_7124641_8 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000000000000000000000000000005077 242.0
HKD1_k127_7124641_9 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000004103 218.0
HKD1_k127_7133797_0 PFAM UDP-glucose GDP-mannose dehydrogenase K00012,K00066,K02472,K02474,K13015 - 1.1.1.132,1.1.1.136,1.1.1.22,1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 483.0
HKD1_k127_7133797_1 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 329.0
HKD1_k127_7133797_10 cheY-homologous receiver domain - - - 0.00000001103 67.0
HKD1_k127_7133797_11 NAD(P)H-binding - - - 0.0000002327 52.0
HKD1_k127_7133797_2 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 329.0
HKD1_k127_7133797_3 ABC transporter related K01990,K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001708 269.0
HKD1_k127_7133797_4 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004599 254.0
HKD1_k127_7133797_5 PFAM Glycosyl K12994 - 2.4.1.349 0.000000000000000000000000000000000000000000000000000000000001065 225.0
HKD1_k127_7133797_6 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000001028 214.0
HKD1_k127_7133797_7 PFAM ABC-2 type transporter K01992,K09690 - - 0.000000000000000000000000000000000000000000000000000001255 201.0
HKD1_k127_7133797_8 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000002263 193.0
HKD1_k127_7133797_9 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000002392 175.0
HKD1_k127_7203718_0 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 3.074e-229 714.0
HKD1_k127_7203718_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 596.0
HKD1_k127_7203718_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000002272 146.0
HKD1_k127_7203718_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000001798 126.0
HKD1_k127_7203718_12 Protein of unknown function (DUF1349) - - - 0.000000000000000000000000000000459 143.0
HKD1_k127_7203718_13 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000001507 115.0
HKD1_k127_7203718_14 cell redox homeostasis - - - 0.000000000000000001698 87.0
HKD1_k127_7203718_15 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K13818 - 2.7.7.77 0.00000000000005943 83.0
HKD1_k127_7203718_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 538.0
HKD1_k127_7203718_3 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 424.0
HKD1_k127_7203718_4 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 432.0
HKD1_k127_7203718_5 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 357.0
HKD1_k127_7203718_6 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 324.0
HKD1_k127_7203718_7 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000008899 257.0
HKD1_k127_7203718_8 ribonuclease III activity K03685,K07053 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3,3.1.3.97 0.0000000000000000000000000000000000000000000000000000158 198.0
HKD1_k127_7203718_9 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000233 198.0
HKD1_k127_7235276_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 543.0
HKD1_k127_7235276_1 Chalcone and stilbene synthases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 435.0
HKD1_k127_7235276_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 422.0
HKD1_k127_7235276_3 ThiF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 376.0
HKD1_k127_7235276_4 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 376.0
HKD1_k127_7235276_5 Abc transporter K01990,K16907 - - 0.0000000000000000000000000000000001047 136.0
HKD1_k127_7235276_6 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.0000000000000000000000000000001845 128.0
HKD1_k127_7235276_7 sulfur carrier activity - - - 0.000000000000000001345 89.0
HKD1_k127_7264272_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 8.625e-223 696.0
HKD1_k127_7264272_1 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 458.0
HKD1_k127_7264272_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 459.0
HKD1_k127_7264272_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 444.0
HKD1_k127_7264272_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 415.0
HKD1_k127_7264272_5 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 327.0
HKD1_k127_7264272_6 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 314.0
HKD1_k127_7264272_7 Receptor family ligand binding region K01999 - - 0.000000000008874 66.0
HKD1_k127_7271439_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 422.0
HKD1_k127_7271439_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000003092 219.0
HKD1_k127_7271439_2 methyltransferase activity - - - 0.0000000000000000000000000000000000000000004454 166.0
HKD1_k127_7271439_3 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000005341 153.0
HKD1_k127_7271439_4 PFAM FMN-binding domain - - - 0.000000000000000000000000000000000002502 153.0
HKD1_k127_7271439_5 Carbohydrate binding domain - - - 0.0000000000000001199 92.0
HKD1_k127_7297914_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1179.0
HKD1_k127_7297914_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 449.0
HKD1_k127_7297914_10 electron transfer activity K05337,K17247 - - 0.0000000000000000000001359 98.0
HKD1_k127_7297914_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 432.0
HKD1_k127_7297914_3 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 345.0
HKD1_k127_7297914_4 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009641 255.0
HKD1_k127_7297914_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000002402 236.0
HKD1_k127_7297914_6 - - - - 0.0000000000000000000000000000000000000000000000000000000003747 206.0
HKD1_k127_7297914_7 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000001698 183.0
HKD1_k127_7297914_8 Peptidase family M50 - - - 0.000000000000000000000000000000004608 130.0
HKD1_k127_7297914_9 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000001964 114.0
HKD1_k127_7305904_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 3.197e-316 986.0
HKD1_k127_7305904_1 2Fe-2S -binding domain K13483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002281 281.0
HKD1_k127_7305904_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000004677 243.0
HKD1_k127_7305904_3 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000001698 181.0
HKD1_k127_7340475_0 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 301.0
HKD1_k127_7340475_1 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 286.0
HKD1_k127_7340475_2 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001284 270.0
HKD1_k127_7340475_3 Pfam:TPM K08988 - - 0.000000000000000000000000000000000000000000000000000001205 199.0
HKD1_k127_7340475_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000001274 173.0
HKD1_k127_7366846_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1148.0
HKD1_k127_7366846_1 growth of symbiont in host cell K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 511.0
HKD1_k127_7366846_10 - - - - 0.00000000000000000001072 96.0
HKD1_k127_7366846_11 - - - - 0.0000000000000000003705 88.0
HKD1_k127_7366846_13 - - - - 0.00000000000000483 76.0
HKD1_k127_7366846_14 UPF0391 membrane protein - - - 0.000000000002142 68.0
HKD1_k127_7366846_15 Protein of unknown function (DUF3096) - - - 0.00000000006874 63.0
HKD1_k127_7366846_16 Protein of unknown function (DUF3096) - - - 0.00000000007233 63.0
HKD1_k127_7366846_17 Protein of unknown function (DUF3096) - - - 0.000000001938 59.0
HKD1_k127_7366846_18 YXWGXW repeat (2 copies) - - - 0.00002373 52.0
HKD1_k127_7366846_2 COGs COG1914 Mn2 and Fe2 transporter of the NRAMP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 390.0
HKD1_k127_7366846_3 phosphoglycolate phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 332.0
HKD1_k127_7366846_4 tRNA 3'-trailer cleavage - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 305.0
HKD1_k127_7366846_5 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008838 269.0
HKD1_k127_7366846_6 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000000001037 116.0
HKD1_k127_7366846_7 - - - - 0.000000000000000000000000001578 115.0
HKD1_k127_7366846_8 - - - - 0.0000000000000000000000001296 108.0
HKD1_k127_7366846_9 PFAM Transglycosylase-associated protein - - - 0.0000000000000000000000006511 105.0
HKD1_k127_7411308_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182,K16239,K16874 - 4.1.1.61,4.1.1.98 6.74e-211 665.0
HKD1_k127_7411308_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 454.0
HKD1_k127_7411308_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000001726 117.0
HKD1_k127_7411308_11 - - - - 0.000000000000000000000003399 108.0
HKD1_k127_7411308_13 membrane K08972 - - 0.00000000000000000000006937 102.0
HKD1_k127_7411308_14 gas vesicle protein - - - 0.00000008575 64.0
HKD1_k127_7411308_15 Recombinase - - - 0.000686 44.0
HKD1_k127_7411308_2 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 421.0
HKD1_k127_7411308_3 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 323.0
HKD1_k127_7411308_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001793 245.0
HKD1_k127_7411308_5 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000001843 186.0
HKD1_k127_7411308_6 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000000000000000000000000000000000000005602 155.0
HKD1_k127_7411308_7 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000001396 151.0
HKD1_k127_7411308_8 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000001947 121.0
HKD1_k127_7411308_9 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000001003 118.0
HKD1_k127_7413258_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 550.0
HKD1_k127_7413258_1 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 478.0
HKD1_k127_7413258_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 355.0
HKD1_k127_7413258_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 322.0
HKD1_k127_7413258_4 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005277 272.0
HKD1_k127_7413258_5 DnaJ central domain K09504 GO:0000002,GO:0000122,GO:0001775,GO:0001776,GO:0001932,GO:0001933,GO:0001941,GO:0001959,GO:0001960,GO:0002119,GO:0002164,GO:0002260,GO:0002376,GO:0002520,GO:0002521,GO:0002682,GO:0002683,GO:0002684,GO:0002694,GO:0002696,GO:0003674,GO:0005102,GO:0005113,GO:0005126,GO:0005133,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006264,GO:0006355,GO:0006357,GO:0006457,GO:0006469,GO:0006725,GO:0006807,GO:0006915,GO:0006919,GO:0006924,GO:0006950,GO:0006952,GO:0006955,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007166,GO:0007224,GO:0007264,GO:0007275,GO:0007528,GO:0007568,GO:0007569,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008285,GO:0009058,GO:0009059,GO:0009295,GO:0009790,GO:0009791,GO:0009792,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010556,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0010941,GO:0010942,GO:0010950,GO:0010951,GO:0010952,GO:0012501,GO:0016020,GO:0016043,GO:0019219,GO:0019220,GO:0019222,GO:0019897,GO:0019898,GO:0019899,GO:0019900,GO:0019901,GO:0022407,GO:0022409,GO:0023051,GO:0023052,GO:0023057,GO:0030097,GO:0030098,GO:0030154,GO:0030155,GO:0030162,GO:0030217,GO:0030234,GO:0030544,GO:0030695,GO:0030971,GO:0031072,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031347,GO:0031348,GO:0031396,GO:0031398,GO:0031399,GO:0031400,GO:0031401,GO:0031594,GO:0031647,GO:0031974,GO:0032042,GO:0032088,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032944,GO:0032946,GO:0033036,GO:0033077,GO:0033673,GO:0034097,GO:0034341,GO:0034613,GO:0034641,GO:0034645,GO:0035556,GO:0042102,GO:0042110,GO:0042127,GO:0042129,GO:0042221,GO:0042325,GO:0042326,GO:0042592,GO:0042645,GO:0042981,GO:0043029,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043086,GO:0043113,GO:0043122,GO:0043124,GO:0043154,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043280,GO:0043281,GO:0043433,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044464,GO:0045087,GO:0045088,GO:0045202,GO:0045211,GO:0045321,GO:0045785,GO:0045824,GO:0045859,GO:0045861,GO:0045862,GO:0045892,GO:0045934,GO:0045936,GO:0046483,GO:0046649,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048869,GO:0048872,GO:0050670,GO:0050671,GO:0050776,GO:0050777,GO:0050789,GO:0050790,GO:0050794,GO:0050808,GO:0050821,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0051059,GO:0051082,GO:0051090,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051251,GO:0051252,GO:0051253,GO:0051336,GO:0051338,GO:0051345,GO:0051346,GO:0051348,GO:0051641,GO:0051668,GO:0051716,GO:0052547,GO:0052548,GO:0060255,GO:0060330,GO:0060331,GO:0060334,GO:0060336,GO:0060548,GO:0060589,GO:0060759,GO:0060761,GO:0061024,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070227,GO:0070231,GO:0070663,GO:0070665,GO:0070727,GO:0071340,GO:0071704,GO:0071840,GO:0071887,GO:0071944,GO:0072657,GO:0080090,GO:0080134,GO:0090304,GO:0097060,GO:0098590,GO:0098772,GO:0098794,GO:0099173,GO:1901360,GO:1901576,GO:1902531,GO:1902532,GO:1902679,GO:1903037,GO:1903039,GO:1903320,GO:1903322,GO:1903506,GO:1903507,GO:1990782,GO:2000112,GO:2000113,GO:2000116,GO:2000117,GO:2001056,GO:2001141 - 0.00000003414 64.0
HKD1_k127_7431421_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 7.054e-240 753.0
HKD1_k127_7431421_1 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 439.0
HKD1_k127_7431421_10 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000001134 74.0
HKD1_k127_7431421_11 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000004838 70.0
HKD1_k127_7431421_12 Heat shock protein DnaJ domain protein - - - 0.00000000007004 76.0
HKD1_k127_7431421_13 PFAM Calcineurin-like phosphoesterase K07098 - - 0.0000002968 53.0
HKD1_k127_7431421_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 310.0
HKD1_k127_7431421_3 MlaD protein K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003228 258.0
HKD1_k127_7431421_4 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000001008 253.0
HKD1_k127_7431421_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000005378 213.0
HKD1_k127_7431421_6 - - - - 0.0000000000000000000000000000007671 126.0
HKD1_k127_7431421_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000002381 119.0
HKD1_k127_7431421_8 Protein of unknown function (DUF3141) - - - 0.00000000000000000000003818 99.0
HKD1_k127_7431421_9 AcrB/AcrD/AcrF family - - - 0.000000000000000138 82.0
HKD1_k127_7557601_0 PFAM Xylulose 5-phosphate Fructose 6-phosphate phosphoketolase, N-terminal K01621 GO:0003674,GO:0003824,GO:0008150,GO:0009758 4.1.2.22,4.1.2.9 0.0 1436.0
HKD1_k127_7557601_1 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.00000000000000000000000000000000000000000000000000000000002885 209.0
HKD1_k127_7557601_2 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000001097 121.0
HKD1_k127_7557601_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000004155 54.0
HKD1_k127_7557601_4 - - - - 0.00008707 52.0
HKD1_k127_7566488_0 Von Willebrand factor type A K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 453.0
HKD1_k127_7566488_1 CbbQ/NirQ/NorQ C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000002496 232.0
HKD1_k127_7566488_2 Sigma-54 interaction domain K06714 - - 0.0000000000000000000000000000000000001253 144.0
HKD1_k127_76988_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.559e-281 874.0
HKD1_k127_76988_1 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 6.542e-275 868.0
HKD1_k127_76988_10 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000138 258.0
HKD1_k127_76988_11 cell division K09812 GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000007655 234.0
HKD1_k127_76988_12 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000001375 234.0
HKD1_k127_76988_13 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000004094 205.0
HKD1_k127_76988_14 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000001843 202.0
HKD1_k127_76988_15 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.00000000000000000000000000000000001811 146.0
HKD1_k127_76988_16 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000216 117.0
HKD1_k127_76988_17 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000003405 108.0
HKD1_k127_76988_18 - - - - 0.000000000000000000001113 100.0
HKD1_k127_76988_19 response regulator, receiver - - - 0.0001635 54.0
HKD1_k127_76988_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007709 571.0
HKD1_k127_76988_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 545.0
HKD1_k127_76988_4 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 499.0
HKD1_k127_76988_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 452.0
HKD1_k127_76988_6 PFAM PfkB K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 375.0
HKD1_k127_76988_7 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 317.0
HKD1_k127_76988_8 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002138 282.0
HKD1_k127_76988_9 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000005619 267.0
HKD1_k127_7709838_0 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000009385 172.0
HKD1_k127_7709838_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000001466 141.0
HKD1_k127_7709838_2 peptidyl-tyrosine sulfation - - - 0.0000000000000001047 91.0
HKD1_k127_7709838_3 Tellurite resistance protein TehB - - - 0.000000000005531 71.0
HKD1_k127_7713144_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1403.0
HKD1_k127_7713144_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 4.162e-277 869.0
HKD1_k127_7713144_10 anaerobic respiration - - - 0.000000000000000000000000000008797 130.0
HKD1_k127_7713144_11 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.0000000000000000000005335 99.0
HKD1_k127_7713144_12 Tetratricopeptide repeats - - - 0.00000001516 66.0
HKD1_k127_7713144_13 sulfur relay protein TusB DsrH K07237 - - 0.000002617 53.0
HKD1_k127_7713144_14 Tfp pilus assembly protein FimV - - - 0.00001183 58.0
HKD1_k127_7713144_15 DsrE/DsrF-like family K07235 - - 0.0002127 46.0
HKD1_k127_7713144_16 PFAM DsrE family protein K07236 - - 0.0002688 48.0
HKD1_k127_7713144_17 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0006069 52.0
HKD1_k127_7713144_2 diguanylate cyclase - - - 1.115e-262 831.0
HKD1_k127_7713144_3 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 484.0
HKD1_k127_7713144_4 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 406.0
HKD1_k127_7713144_5 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 320.0
HKD1_k127_7713144_6 ribonuclease BN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 300.0
HKD1_k127_7713144_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001283 286.0
HKD1_k127_7713144_8 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000002378 220.0
HKD1_k127_7713144_9 - - - - 0.00000000000000000000000000000000000000000000000004161 203.0
HKD1_k127_7750522_0 cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 472.0
HKD1_k127_7750522_1 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 439.0
HKD1_k127_7750522_10 Redoxin K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000002071 256.0
HKD1_k127_7750522_11 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004157 254.0
HKD1_k127_7750522_12 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000004987 227.0
HKD1_k127_7750522_13 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000001826 202.0
HKD1_k127_7750522_14 Histidine kinase K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000001326 190.0
HKD1_k127_7750522_15 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000004776 153.0
HKD1_k127_7750522_16 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000007046 149.0
HKD1_k127_7750522_17 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000000000000000000009247 156.0
HKD1_k127_7750522_18 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000002957 146.0
HKD1_k127_7750522_19 phosphorelay signal transduction system - - - 0.0000000000000000000000000000001323 129.0
HKD1_k127_7750522_2 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 432.0
HKD1_k127_7750522_20 lyase activity - - - 0.0000000000000000000000000002748 124.0
HKD1_k127_7750522_21 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000013 113.0
HKD1_k127_7750522_22 Protein of unknown function (DUF1264) - - - 0.0000000000000000002133 94.0
HKD1_k127_7750522_23 Rubrerythrin - - - 0.00000000000001093 80.0
HKD1_k127_7750522_25 radical SAM domain protein - - - 0.000000000006395 70.0
HKD1_k127_7750522_26 Bacterial antitoxin of type II TA system, VapB - - - 0.0003797 46.0
HKD1_k127_7750522_3 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 395.0
HKD1_k127_7750522_4 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 375.0
HKD1_k127_7750522_5 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 371.0
HKD1_k127_7750522_6 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 366.0
HKD1_k127_7750522_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009778 333.0
HKD1_k127_7750522_8 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 347.0
HKD1_k127_7750522_9 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002393 287.0
HKD1_k127_7785007_0 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000002746 229.0
HKD1_k127_7785007_1 Uncharacterised nucleotidyltransferase - - - 0.0000000004854 70.0
HKD1_k127_7785007_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00001036 48.0
HKD1_k127_7818847_0 Sensor histidine kinase, HAMP domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 449.0
HKD1_k127_7818847_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 426.0
HKD1_k127_7818847_10 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000001878 106.0
HKD1_k127_7818847_11 antisigma factor binding K04749 - - 0.00000000000009752 75.0
HKD1_k127_7818847_12 MlaD protein K02067 - - 0.00000002205 65.0
HKD1_k127_7818847_13 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000006614 56.0
HKD1_k127_7818847_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 317.0
HKD1_k127_7818847_3 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 295.0
HKD1_k127_7818847_4 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004132 276.0
HKD1_k127_7818847_5 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001124 269.0
HKD1_k127_7818847_6 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000002641 246.0
HKD1_k127_7818847_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001084 250.0
HKD1_k127_7818847_8 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000002819 194.0
HKD1_k127_7818847_9 Protein of unknown function (DUF3187) - - - 0.000000000000000000000000006108 122.0
HKD1_k127_7894814_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 585.0
HKD1_k127_7894814_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 509.0
HKD1_k127_7894814_10 Transcriptional regulator - - - 0.0000000000000000000000000000000000000004181 157.0
HKD1_k127_7894814_11 AMP binding - - - 0.00000000000000000000000000000000000001094 148.0
HKD1_k127_7894814_12 Thiamine-binding protein - - - 0.0000000000000000000000000000000007285 133.0
HKD1_k127_7894814_13 AMP binding - - - 0.0000000000000000000000000000000549 137.0
HKD1_k127_7894814_14 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000002055 125.0
HKD1_k127_7894814_15 - - - - 0.00000000000000001009 87.0
HKD1_k127_7894814_16 PFAM Pterin binding enzyme K00548 - 2.1.1.13 0.000000000003791 76.0
HKD1_k127_7894814_17 O-Antigen ligase - - - 0.0000000003737 72.0
HKD1_k127_7894814_18 PFAM Rhodanese domain protein - - - 0.0000000008365 66.0
HKD1_k127_7894814_19 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.00001554 55.0
HKD1_k127_7894814_2 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 457.0
HKD1_k127_7894814_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 366.0
HKD1_k127_7894814_4 calcium, potassium:sodium antiporter activity K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 358.0
HKD1_k127_7894814_5 transferase activity, transferring glycosyl groups K13500 - 2.4.1.175,2.4.1.226 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 307.0
HKD1_k127_7894814_6 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007316 280.0
HKD1_k127_7894814_7 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000145 266.0
HKD1_k127_7894814_8 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000007474 241.0
HKD1_k127_7894814_9 Catalyzes the reversible hydration of fumarate to (S)- malate K01676,K03780 - 4.2.1.2,4.2.1.32 0.0000000000000000000000000000000000000000000000000000003125 205.0
HKD1_k127_8029977_0 RNA polymerase I subunit A N-terminus K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 469.0
HKD1_k127_8029977_1 phosphorelay signal transduction system K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 434.0
HKD1_k127_8029977_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 316.0
HKD1_k127_8029977_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000006145 209.0
HKD1_k127_8029977_4 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.0000000000000000000000000000000000000000000000005147 184.0
HKD1_k127_8029977_5 heme-binding sites - - - 0.000000000000000000000000000000000000008559 154.0
HKD1_k127_8029977_6 formate dehydrogenase - - - 0.0000000000000000000000000000000002749 143.0
HKD1_k127_8029977_7 tetratricopeptide repeat - - - 0.0000000000000000000000000000000253 134.0
HKD1_k127_8029977_8 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000001772 126.0
HKD1_k127_8029977_9 Mannosyltransferase (PIG-V) - - - 0.00000000000000000000000006279 121.0
HKD1_k127_812812_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 3.223e-282 897.0
HKD1_k127_812812_1 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 439.0
HKD1_k127_812812_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000005005 185.0
HKD1_k127_812812_3 - - - - 0.000000000000000000000000000000006511 138.0
HKD1_k127_812812_4 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.000000000000000000000000000002663 121.0
HKD1_k127_812812_5 Thioredoxin K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.000000000000000000000000000009605 124.0
HKD1_k127_852913_0 alginic acid biosynthetic process - - - 4.353e-273 865.0
HKD1_k127_852913_1 Predicted permease K07089 - - 1.279e-241 762.0
HKD1_k127_852913_11 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000005549 235.0
HKD1_k127_852913_12 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000008938 216.0
HKD1_k127_852913_14 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000001245 196.0
HKD1_k127_852913_15 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000001139 193.0
HKD1_k127_852913_18 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000003585 186.0
HKD1_k127_852913_19 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000001099 169.0
HKD1_k127_852913_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009788 571.0
HKD1_k127_852913_20 glycine betaine transport K05845,K05846 - - 0.000000000000000000000000000000000000000000004897 170.0
HKD1_k127_852913_21 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000001463 148.0
HKD1_k127_852913_23 - - - - 0.000000000000000000005015 93.0
HKD1_k127_852913_24 response regulator K02479,K07684,K07685 - - 0.000001395 58.0
HKD1_k127_852913_25 peptidyl-tyrosine sulfation - - - 0.000002014 57.0
HKD1_k127_852913_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 533.0
HKD1_k127_852913_4 SMART Elongator protein 3 MiaB NifB K22226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 492.0
HKD1_k127_852913_5 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 349.0
HKD1_k127_852913_6 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 343.0
HKD1_k127_852913_7 cytochrome c biogenesis protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 323.0
HKD1_k127_852913_8 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 321.0
HKD1_k127_852913_9 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 296.0
HKD1_k127_919460_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1087.0
HKD1_k127_919460_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 1.155e-304 940.0
HKD1_k127_919460_2 porphobilinogen synthase activity K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 321.0
HKD1_k127_919460_3 PFAM Glutamine amidotransferase, class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 298.0
HKD1_k127_919460_4 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000309 143.0
HKD1_k127_919460_5 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000000006592 119.0
HKD1_k127_934001_0 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000000902 216.0
HKD1_k127_934001_1 Prokaryotic N-terminal methylation motif K02457 - - 0.0000000000000000000001696 103.0
HKD1_k127_934001_2 Type II secretion system (T2SS), protein J K02459 - - 0.00000000000000000006708 99.0
HKD1_k127_934001_3 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000001057 97.0
HKD1_k127_934001_5 - - - - 0.0000000000000009189 88.0
HKD1_k127_934001_6 general secretion pathway protein K02456,K02457,K02458,K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000001807 69.0
HKD1_k127_934001_7 Type II secretion system (T2SS), protein M K02462 - - 0.000000000973 67.0
HKD1_k127_934001_8 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000419 49.0
HKD1_k127_943255_0 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 563.0
HKD1_k127_943255_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 410.0
HKD1_k127_943255_2 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 376.0
HKD1_k127_943255_3 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 302.0
HKD1_k127_943255_4 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000001215 204.0
HKD1_k127_943255_5 protein homooligomerization - - - 0.00000000000000000000000000000000000000000000000001992 194.0
HKD1_k127_943255_6 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000001379 159.0
HKD1_k127_943255_7 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000001978 120.0
HKD1_k127_943255_8 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000846 117.0