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Overview

ID MAG01707
Name HKD1_bin.2
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order UBA5066
Family Gp7-AA6
Genus DAHUXD01
Species
Assembly information
Completeness (%) 89.17
Contamination (%) 1.51
GC content (%) 71.0
N50 (bp) 22,682
Genome size (bp) 3,431,105

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2958

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1006063_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 2.452e-306 975.0
HKD1_k127_1006063_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 582.0
HKD1_k127_1006063_2 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 384.0
HKD1_k127_1006063_3 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000003357 251.0
HKD1_k127_1006063_4 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000002347 234.0
HKD1_k127_1006063_5 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000003209 195.0
HKD1_k127_1006063_6 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000006979 157.0
HKD1_k127_1006063_7 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000001731 147.0
HKD1_k127_1006063_9 BON domain - - - 0.00000000000000004049 83.0
HKD1_k127_1026298_0 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000003391 133.0
HKD1_k127_1026298_1 peptidase - - - 0.000000000000000000000000000001225 128.0
HKD1_k127_1026298_2 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.000000000000000000000000001072 118.0
HKD1_k127_1026298_3 Protein of unknown function (DUF1326) - - - 0.00005941 48.0
HKD1_k127_1026722_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0016829,GO:0016830,GO:0016833 4.1.3.1 0.0 1194.0
HKD1_k127_1026722_1 Belongs to the malate synthase family K01638 - 2.3.3.9 8.468e-299 927.0
HKD1_k127_1026722_10 FAD binding domain K00486 - 1.14.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 452.0
HKD1_k127_1026722_11 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 451.0
HKD1_k127_1026722_12 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 449.0
HKD1_k127_1026722_13 tryptophan 2,3-dioxygenase activity K00453,K03392 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11,4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 408.0
HKD1_k127_1026722_14 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 419.0
HKD1_k127_1026722_15 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 374.0
HKD1_k127_1026722_16 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 357.0
HKD1_k127_1026722_17 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 340.0
HKD1_k127_1026722_18 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 319.0
HKD1_k127_1026722_19 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 323.0
HKD1_k127_1026722_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 2.856e-219 696.0
HKD1_k127_1026722_20 Protein of unknown function (DUF1348) K09958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 295.0
HKD1_k127_1026722_21 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001434 283.0
HKD1_k127_1026722_22 3-hydroxyanthranilic acid dioxygenase K00452 - 1.13.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000003305 263.0
HKD1_k127_1026722_23 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005335 263.0
HKD1_k127_1026722_24 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000009668 244.0
HKD1_k127_1026722_25 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000003726 229.0
HKD1_k127_1026722_26 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000008511 200.0
HKD1_k127_1026722_27 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000005462 201.0
HKD1_k127_1026722_28 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000002508 206.0
HKD1_k127_1026722_29 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K01647,K22491 - 2.3.3.1 0.000000000000000000000000000000000000000000000000221 188.0
HKD1_k127_1026722_3 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 8.374e-209 672.0
HKD1_k127_1026722_30 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000001577 185.0
HKD1_k127_1026722_31 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000001497 181.0
HKD1_k127_1026722_32 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000003742 183.0
HKD1_k127_1026722_33 gluconolactonase activity - - - 0.000000000000000000000000000000000000000007753 175.0
HKD1_k127_1026722_34 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000002649 164.0
HKD1_k127_1026722_35 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000002762 170.0
HKD1_k127_1026722_36 Translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.0000000000000000000000000000000000001082 148.0
HKD1_k127_1026722_37 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000001457 150.0
HKD1_k127_1026722_38 Amidohydrolase family - - - 0.000000000000000000000000000000000001571 153.0
HKD1_k127_1026722_39 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000008093 156.0
HKD1_k127_1026722_4 PFAM NAD-dependent epimerase dehydratase - - - 1.525e-201 638.0
HKD1_k127_1026722_40 Helix-hairpin-helix motif - - - 0.000000000000000000000000000000004896 141.0
HKD1_k127_1026722_41 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000000002218 133.0
HKD1_k127_1026722_42 Cupredoxin-like domain - - - 0.00000000000001151 87.0
HKD1_k127_1026722_43 universal stress protein K06149 - - 0.000000000003732 73.0
HKD1_k127_1026722_45 GCN5-related N-acetyl-transferase K06975 - - 0.00000000004992 67.0
HKD1_k127_1026722_46 TPR repeat - - - 0.0000000002701 73.0
HKD1_k127_1026722_47 peptidyl-tyrosine sulfation - - - 0.000000003092 66.0
HKD1_k127_1026722_48 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K02005 - - 0.00000003671 66.0
HKD1_k127_1026722_49 DNA uptake protein and related DNA-binding K02237 - - 0.000000257 62.0
HKD1_k127_1026722_5 Belongs to the aldehyde dehydrogenase family K00128,K00138,K10217 - 1.2.1.3,1.2.1.32,1.2.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 612.0
HKD1_k127_1026722_50 Domain of unknown function (DUF4136) - - - 0.0000003567 61.0
HKD1_k127_1026722_54 energy transducer activity K03832 - - 0.0002778 52.0
HKD1_k127_1026722_6 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 542.0
HKD1_k127_1026722_7 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 550.0
HKD1_k127_1026722_8 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 469.0
HKD1_k127_1026722_9 FAD dependent oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 475.0
HKD1_k127_1038965_0 Belongs to the glycosyl hydrolase 57 family - - - 1.111e-311 974.0
HKD1_k127_1038965_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.994e-303 946.0
HKD1_k127_1038965_2 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 584.0
HKD1_k127_1038965_3 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 464.0
HKD1_k127_1038965_4 Mandelate racemase muconate lactonizing enzyme K02549,K19802 - 4.2.1.113,5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 436.0
HKD1_k127_1095071_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.239e-235 747.0
HKD1_k127_1095071_1 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 510.0
HKD1_k127_1095071_10 Represses a number of genes involved in the response to DNA damage (SOS response) K01356,K03503 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000001184 195.0
HKD1_k127_1095071_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000002514 156.0
HKD1_k127_1095071_12 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000003471 145.0
HKD1_k127_1095071_15 Protein of unknown function, DUF255 - - - 0.0000006026 61.0
HKD1_k127_1095071_16 - - - - 0.0001854 49.0
HKD1_k127_1095071_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 509.0
HKD1_k127_1095071_3 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 453.0
HKD1_k127_1095071_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 434.0
HKD1_k127_1095071_5 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 361.0
HKD1_k127_1095071_6 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 317.0
HKD1_k127_1095071_7 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002354 246.0
HKD1_k127_1095071_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000007257 226.0
HKD1_k127_1095071_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000004041 213.0
HKD1_k127_1103476_0 antibiotic catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000946 226.0
HKD1_k127_1103476_1 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000377 159.0
HKD1_k127_1103563_0 GTP-binding protein TypA K06207 - - 8.826e-205 654.0
HKD1_k127_1103563_1 DNA helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 438.0
HKD1_k127_1103563_2 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007336 276.0
HKD1_k127_1103563_3 Pkd domain containing protein K12567 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000008371 240.0
HKD1_k127_1103563_4 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000006236 170.0
HKD1_k127_1103563_5 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000002282 156.0
HKD1_k127_1103563_7 amine dehydrogenase activity - - - 0.0004319 53.0
HKD1_k127_1112654_0 ABC transporter, transmembrane K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 520.0
HKD1_k127_1112654_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 499.0
HKD1_k127_1112654_2 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 485.0
HKD1_k127_1112654_3 Belongs to the BI1 family K06890,K19416 - - 0.0000005859 51.0
HKD1_k127_1139669_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 590.0
HKD1_k127_1139669_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 359.0
HKD1_k127_1139669_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 362.0
HKD1_k127_1139669_3 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000002005 127.0
HKD1_k127_1139669_4 - - - - 0.0000000000000000000005117 106.0
HKD1_k127_1139669_5 With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate K03154 - - 0.00000000000246 81.0
HKD1_k127_1151370_0 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 396.0
HKD1_k127_1151370_1 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 389.0
HKD1_k127_1151370_2 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 336.0
HKD1_k127_1151370_3 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000257 253.0
HKD1_k127_1151370_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000001636 237.0
HKD1_k127_1151370_5 Protein of unknown function (DUF1573) - - - 0.00000000000001385 85.0
HKD1_k127_1151370_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000002624 69.0
HKD1_k127_1151370_7 AIR carboxylase K06898 - - 0.000006897 51.0
HKD1_k127_1160509_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 623.0
HKD1_k127_1160509_1 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 524.0
HKD1_k127_1160509_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000002387 229.0
HKD1_k127_1160509_3 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.000000000000000000000000000001005 130.0
HKD1_k127_1160509_4 succinylglutamate desuccinylase K06987 - - 0.00000000000000000000001586 115.0
HKD1_k127_1209504_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 543.0
HKD1_k127_1209504_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K03918,K07250,K13524 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 509.0
HKD1_k127_1209504_10 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000002188 218.0
HKD1_k127_1209504_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000005025 219.0
HKD1_k127_1209504_12 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000006125 190.0
HKD1_k127_1209504_13 guanosine tetraphosphate metabolic process K07816 - 2.7.6.5 0.000000000000000000000000000000000000000000000000003753 205.0
HKD1_k127_1209504_14 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000002483 196.0
HKD1_k127_1209504_15 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000009966 182.0
HKD1_k127_1209504_16 GAF domain - - - 0.00000000000000000000000000000000000000000000002062 189.0
HKD1_k127_1209504_17 - - - - 0.00000000000000000000000000000000000004049 149.0
HKD1_k127_1209504_18 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000003552 143.0
HKD1_k127_1209504_19 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000001672 139.0
HKD1_k127_1209504_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 449.0
HKD1_k127_1209504_21 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000002091 132.0
HKD1_k127_1209504_22 methyltransferase activity - - - 0.000000000000000000000000003023 123.0
HKD1_k127_1209504_24 Subtilase family - - - 0.0007555 52.0
HKD1_k127_1209504_3 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 448.0
HKD1_k127_1209504_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 449.0
HKD1_k127_1209504_5 Ring hydroxylating alpha subunit (catalytic domain) K00479,K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 428.0
HKD1_k127_1209504_6 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 367.0
HKD1_k127_1209504_7 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008781 262.0
HKD1_k127_1209504_8 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000001031 261.0
HKD1_k127_1209504_9 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001997 260.0
HKD1_k127_1218871_0 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 403.0
HKD1_k127_1218871_1 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 324.0
HKD1_k127_1218871_2 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000001372 205.0
HKD1_k127_1218871_3 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000004287 208.0
HKD1_k127_1218871_4 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.000000000000000000000000000000000000000000000000001039 199.0
HKD1_k127_1218871_5 RibD C-terminal domain - - - 0.0000000000000000000000000000001813 130.0
HKD1_k127_1218871_6 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000002068 126.0
HKD1_k127_1246283_0 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 537.0
HKD1_k127_1246283_1 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 336.0
HKD1_k127_1246283_2 Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000008905 76.0
HKD1_k127_1258141_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 407.0
HKD1_k127_1258141_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000003478 70.0
HKD1_k127_1258141_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000008382 61.0
HKD1_k127_1258141_3 ATP synthase B/B' CF(0) K02109 - - 0.00001614 53.0
HKD1_k127_1258141_4 Integral membrane protein CcmA involved in cell shape determination - - - 0.00004682 47.0
HKD1_k127_1259908_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000003262 178.0
HKD1_k127_1259908_1 mRNA binding - - - 0.000000000000000000002393 95.0
HKD1_k127_1259908_2 Fibronectin type 3 domain - - - 0.00000000000000005511 93.0
HKD1_k127_1259908_3 PFAM Uncharacterised protein family UPF0150 - - - 0.00000002945 55.0
HKD1_k127_1260816_0 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 594.0
HKD1_k127_1260816_1 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005206 294.0
HKD1_k127_1260816_2 Cys/Met metabolism PLP-dependent enzyme K00812 - 2.6.1.1 0.000000000000000000000000005795 113.0
HKD1_k127_1260816_3 Methionine biosynthesis protein MetW - - - 0.00000000000000000001118 100.0
HKD1_k127_1260816_4 Phospholipase_D-nuclease N-terminal - - - 0.00000000002754 69.0
HKD1_k127_1293005_0 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 584.0
HKD1_k127_1293005_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000009059 192.0
HKD1_k127_1309809_0 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 387.0
HKD1_k127_1309809_1 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000005491 190.0
HKD1_k127_1309809_2 Zinc-binding dehydrogenase K07538 - 1.1.1.368 0.0000000000000000000000000000000000000001297 167.0
HKD1_k127_1345801_0 recA bacterial DNA recombination protein K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 485.0
HKD1_k127_1345801_1 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 447.0
HKD1_k127_1345801_10 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000002751 211.0
HKD1_k127_1345801_11 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000003923 189.0
HKD1_k127_1345801_12 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000003361 145.0
HKD1_k127_1345801_13 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000001068 128.0
HKD1_k127_1345801_14 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000005958 109.0
HKD1_k127_1345801_15 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000004947 106.0
HKD1_k127_1345801_16 Ribosomal L32p protein family K02911 - - 0.000000000000000000001757 96.0
HKD1_k127_1345801_17 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000006268 99.0
HKD1_k127_1345801_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 401.0
HKD1_k127_1345801_3 AICARFT/IMPCHase bienzyme K00602 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 391.0
HKD1_k127_1345801_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 332.0
HKD1_k127_1345801_5 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 320.0
HKD1_k127_1345801_6 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007421 302.0
HKD1_k127_1345801_7 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000009224 249.0
HKD1_k127_1345801_8 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000001933 232.0
HKD1_k127_1345801_9 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000001922 214.0
HKD1_k127_1377674_0 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 467.0
HKD1_k127_1377674_1 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 324.0
HKD1_k127_1377674_10 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000005118 207.0
HKD1_k127_1377674_11 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000001318 205.0
HKD1_k127_1377674_12 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000009894 209.0
HKD1_k127_1377674_13 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000001353 194.0
HKD1_k127_1377674_14 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000006318 187.0
HKD1_k127_1377674_15 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000002885 170.0
HKD1_k127_1377674_16 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000001152 159.0
HKD1_k127_1377674_17 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000001897 142.0
HKD1_k127_1377674_18 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000005219 150.0
HKD1_k127_1377674_19 Methyltransferase domain - - - 0.00000000000000000000000000000001181 136.0
HKD1_k127_1377674_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 322.0
HKD1_k127_1377674_20 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000278 134.0
HKD1_k127_1377674_21 methyltransferase activity K15256 - - 0.0000000000000000000000001716 124.0
HKD1_k127_1377674_22 Competence protein - - - 0.000000000000000000000002488 118.0
HKD1_k127_1377674_23 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000000002674 108.0
HKD1_k127_1377674_24 antisigma factor binding - - - 0.000000000000000000000316 104.0
HKD1_k127_1377674_25 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000006036 110.0
HKD1_k127_1377674_26 chlorophyll binding - - - 0.00000000000000001837 96.0
HKD1_k127_1377674_27 PKD domain - - - 0.000000000000006066 91.0
HKD1_k127_1377674_28 Glycosyl transferase, family 2 - - - 0.0000000000000135 87.0
HKD1_k127_1377674_29 Acetyltransferase (GNAT) domain - - - 0.0000000000001163 85.0
HKD1_k127_1377674_3 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001066 286.0
HKD1_k127_1377674_30 Glycosyltransferase like family 2 K00786,K16555,K19354 GO:0003674,GO:0003824,GO:0005575,GO:0006950,GO:0007154,GO:0008150,GO:0008194,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015020,GO:0016020,GO:0016036,GO:0016740,GO:0016757,GO:0016758,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0050896,GO:0051716,GO:0071496 - 0.000000000002769 80.0
HKD1_k127_1377674_31 Tetratricopeptide repeat - - - 0.000000002467 70.0
HKD1_k127_1377674_32 transcriptional regulator, SARP family - - - 0.0000002523 62.0
HKD1_k127_1377674_33 META domain - - - 0.000002187 61.0
HKD1_k127_1377674_34 Helix-turn-helix - - - 0.000008485 58.0
HKD1_k127_1377674_36 PFAM PEGA domain - - - 0.0001095 54.0
HKD1_k127_1377674_4 Sigma-54 interaction domain K02584,K07713,K15836,K21009 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000217 295.0
HKD1_k127_1377674_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001162 266.0
HKD1_k127_1377674_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000002084 258.0
HKD1_k127_1377674_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000002857 235.0
HKD1_k127_1377674_8 Glycosyltransferase, group 2 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000001297 237.0
HKD1_k127_1377674_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000001899 198.0
HKD1_k127_1380000_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 612.0
HKD1_k127_1380000_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 537.0
HKD1_k127_1380000_10 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000154 176.0
HKD1_k127_1380000_11 - - - - 0.000000000000000000000000000000000000000000002053 170.0
HKD1_k127_1380000_12 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000001323 177.0
HKD1_k127_1380000_13 - - - - 0.00000000000000000000000000000000000000000001393 165.0
HKD1_k127_1380000_14 Cupin domain - - - 0.0000000000000000000000000000000000000000005778 171.0
HKD1_k127_1380000_15 DinB superfamily K07552 - - 0.00000000000000000000000000000000004362 139.0
HKD1_k127_1380000_16 Protein of unknown function (DUF3224) - - - 0.000000000000000000000000000581 123.0
HKD1_k127_1380000_17 Domain of unknown function (DUF1330) - - - 0.000000000000000000000003418 104.0
HKD1_k127_1380000_18 TfoX N-terminal domain - - - 0.00000000000000000000002101 109.0
HKD1_k127_1380000_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 424.0
HKD1_k127_1380000_20 DinB family - - - 0.00000000000000004868 92.0
HKD1_k127_1380000_21 DinB superfamily - - - 0.00000000000006467 72.0
HKD1_k127_1380000_23 - - - - 0.000000002622 63.0
HKD1_k127_1380000_24 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.000000007483 64.0
HKD1_k127_1380000_25 Putative prokaryotic signal transducing protein - - - 0.000007422 59.0
HKD1_k127_1380000_3 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 331.0
HKD1_k127_1380000_4 dihydrofolate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 316.0
HKD1_k127_1380000_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001702 235.0
HKD1_k127_1380000_6 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000001066 242.0
HKD1_k127_1380000_7 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000000000000000009605 220.0
HKD1_k127_1380000_8 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000004512 210.0
HKD1_k127_1380000_9 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000000001064 204.0
HKD1_k127_1420729_0 TIGRFAM FeS assembly protein SufB K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 347.0
HKD1_k127_1420729_1 Lipase maturation factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 319.0
HKD1_k127_1420729_2 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 322.0
HKD1_k127_1422978_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 342.0
HKD1_k127_1422978_1 response to heat K07090 - - 0.00000000000000000000000000123 125.0
HKD1_k127_1422978_2 Glycerophosphoryl diester phosphodiesterase family K01113,K01126 - 3.1.3.1,3.1.4.46 0.00000000000000003939 90.0
HKD1_k127_142530_0 metallopeptidase activity - - - 1.01e-233 764.0
HKD1_k127_142530_1 metallopeptidase activity - - - 7.327e-233 790.0
HKD1_k127_142530_10 - - - - 0.0000000000000002375 90.0
HKD1_k127_142530_11 Domain of unknown function DUF11 - - - 0.0000000000003885 85.0
HKD1_k127_142530_12 Metallo-peptidase family M12 - - - 0.0000000002337 62.0
HKD1_k127_142530_13 ig-like, plexins, transcription factors - - - 0.00006393 56.0
HKD1_k127_142530_2 SPTR Conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000001435 229.0
HKD1_k127_142530_3 gluconolactonase activity K14274,K20276 - - 0.00000000000000000000000000000000000000000000000000000002873 222.0
HKD1_k127_142530_4 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000006366 193.0
HKD1_k127_142530_5 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000000000003279 201.0
HKD1_k127_142530_6 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000000009797 188.0
HKD1_k127_142530_7 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000004 174.0
HKD1_k127_142530_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000238 127.0
HKD1_k127_142530_9 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000001575 89.0
HKD1_k127_1443472_0 Protein kinase domain K12132 - 2.7.11.1 2.158e-238 765.0
HKD1_k127_1443472_1 Protein kinase domain K12132 - 2.7.11.1 2.387e-213 694.0
HKD1_k127_1443472_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 580.0
HKD1_k127_1443472_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 562.0
HKD1_k127_1443472_4 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 338.0
HKD1_k127_1443472_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000001929 56.0
HKD1_k127_1458443_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 407.0
HKD1_k127_1458443_1 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000005179 255.0
HKD1_k127_1458443_2 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000002348 217.0
HKD1_k127_1458443_3 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000003051 192.0
HKD1_k127_1458443_4 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000004024 179.0
HKD1_k127_1458443_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000003958 158.0
HKD1_k127_1458443_6 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000001756 135.0
HKD1_k127_1466589_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000314 63.0
HKD1_k127_1509604_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 453.0
HKD1_k127_1509604_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000131 236.0
HKD1_k127_1509604_2 MOSC domain - - - 0.000000000000000000000000000000000000000000000000003504 184.0
HKD1_k127_1509604_3 Thioesterase K01075 - 3.1.2.23 0.0000000000000000000002523 111.0
HKD1_k127_1578503_0 Aminotransferase class-III K09251 - 2.6.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 542.0
HKD1_k127_1578503_1 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000001928 250.0
HKD1_k127_1578503_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 GO:0003674,GO:0003824,GO:0003867,GO:0008483,GO:0016740,GO:0016769 2.6.1.19,2.6.1.22 0.0000001229 53.0
HKD1_k127_164461_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 8.428e-213 689.0
HKD1_k127_164461_1 Angiotensin-converting enzyme K01283 - 3.4.15.1 8.941e-200 625.0
HKD1_k127_164461_10 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 311.0
HKD1_k127_164461_11 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 301.0
HKD1_k127_164461_12 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000355 262.0
HKD1_k127_164461_13 Squalene/phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000185 267.0
HKD1_k127_164461_14 - K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000007487 249.0
HKD1_k127_164461_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001158 258.0
HKD1_k127_164461_16 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000111 242.0
HKD1_k127_164461_17 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001209 255.0
HKD1_k127_164461_18 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000003167 235.0
HKD1_k127_164461_19 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000000000000000000000004881 239.0
HKD1_k127_164461_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 9.973e-199 628.0
HKD1_k127_164461_20 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000003319 238.0
HKD1_k127_164461_21 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000003189 228.0
HKD1_k127_164461_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.0000000000000000000000000000000000000000000000002439 196.0
HKD1_k127_164461_23 B3 4 domain - - - 0.0000000000000000000000000000000000000000000000006979 188.0
HKD1_k127_164461_24 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000001094 193.0
HKD1_k127_164461_25 DNA-templated transcription, initiation K03088,K07263 - - 0.00000000000000000000000000000000008993 141.0
HKD1_k127_164461_27 phosphoglycerate mutase - - - 0.0000000000000000000005244 106.0
HKD1_k127_164461_28 Predicted periplasmic lipoprotein (DUF2279) - - - 0.00000000006942 76.0
HKD1_k127_164461_29 PFAM purine or other phosphorylase family 1 - - - 0.00001105 57.0
HKD1_k127_164461_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 613.0
HKD1_k127_164461_30 - - - - 0.0008858 53.0
HKD1_k127_164461_4 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 598.0
HKD1_k127_164461_5 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 368.0
HKD1_k127_164461_6 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 376.0
HKD1_k127_164461_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 376.0
HKD1_k127_164461_8 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 323.0
HKD1_k127_164461_9 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 310.0
HKD1_k127_168893_0 Heat shock 70 kDa protein K04043 - - 1.395e-243 768.0
HKD1_k127_168893_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 388.0
HKD1_k127_168893_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000003476 140.0
HKD1_k127_1867457_0 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 351.0
HKD1_k127_1867457_1 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 315.0
HKD1_k127_1867457_2 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000537 245.0
HKD1_k127_1867457_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000001715 232.0
HKD1_k127_1867457_4 Radical SAM domain protein - - - 0.00000001001 69.0
HKD1_k127_1881546_0 Urocanase C-terminal domain K01712 - 4.2.1.49 1.207e-246 779.0
HKD1_k127_1881546_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.83e-208 676.0
HKD1_k127_1881546_10 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000005111 158.0
HKD1_k127_1881546_11 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.00000000000000000000000000000000001425 158.0
HKD1_k127_1881546_12 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000001 117.0
HKD1_k127_1881546_13 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000006276 108.0
HKD1_k127_1881546_14 COG1214 Inactive homolog of metal-dependent proteases K01409,K14742 - 2.3.1.234 0.0000000000000004794 86.0
HKD1_k127_1881546_15 S-acyltransferase activity K02487,K06596,K07576 - - 0.0000000000000008997 90.0
HKD1_k127_1881546_2 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 483.0
HKD1_k127_1881546_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 337.0
HKD1_k127_1881546_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 323.0
HKD1_k127_1881546_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000001046 234.0
HKD1_k127_1881546_6 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.00000000000000000000000000000000000000000000000000000002587 227.0
HKD1_k127_1881546_7 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000001098 198.0
HKD1_k127_1881546_8 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000004127 174.0
HKD1_k127_1881546_9 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000001291 181.0
HKD1_k127_1911431_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 417.0
HKD1_k127_1911431_1 Cytochrome c3 - - - 0.00000000000000000002168 97.0
HKD1_k127_1998431_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.232e-270 839.0
HKD1_k127_1998431_1 exonuclease activity K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 466.0
HKD1_k127_1998431_2 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.0000000001734 68.0
HKD1_k127_2012405_0 Protein kinase domain K12132 - 2.7.11.1 1.114e-226 740.0
HKD1_k127_2012405_1 Involved in the tonB-independent uptake of proteins - - - 5.466e-203 662.0
HKD1_k127_2012405_10 Domain of unknown function (DUF4136) - - - 0.0002573 53.0
HKD1_k127_2012405_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 563.0
HKD1_k127_2012405_3 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 404.0
HKD1_k127_2012405_4 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000006154 227.0
HKD1_k127_2012405_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000001476 137.0
HKD1_k127_2012405_6 toxin-antitoxin pair type II binding - - - 0.000000000000000000001114 96.0
HKD1_k127_2012405_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000386 78.0
HKD1_k127_2012405_9 Carbonic anhydrase K01673 - 4.2.1.1 0.000003497 51.0
HKD1_k127_202265_0 PFAM Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 517.0
HKD1_k127_202265_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 518.0
HKD1_k127_202265_10 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 365.0
HKD1_k127_202265_11 Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 385.0
HKD1_k127_202265_12 3-demethylubiquinone-9 3-O-methyltransferase activity K07011,K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 391.0
HKD1_k127_202265_13 PFAM ABC transporter K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 311.0
HKD1_k127_202265_14 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001319 280.0
HKD1_k127_202265_15 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002167 282.0
HKD1_k127_202265_16 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001212 280.0
HKD1_k127_202265_17 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002128 255.0
HKD1_k127_202265_18 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000002459 216.0
HKD1_k127_202265_19 COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000218 212.0
HKD1_k127_202265_2 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 501.0
HKD1_k127_202265_20 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000009787 222.0
HKD1_k127_202265_21 PFAM glycosyl transferase family 39 K14340 - - 0.000000000000000000000000000000000000000000000001701 199.0
HKD1_k127_202265_22 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000007305 192.0
HKD1_k127_202265_23 Transcriptional regulator - - - 0.000000000000000000000000000000000000003025 154.0
HKD1_k127_202265_24 Transport permease protein K09688,K09690 - - 0.000000000000000000000000000000000001415 153.0
HKD1_k127_202265_25 Peptidase family M20/M25/M40 - - - 0.000000000000000000000000000000000002018 161.0
HKD1_k127_202265_26 - - - - 0.0000000000000000000000000000000007624 151.0
HKD1_k127_202265_27 phosphatase activity K07025 - - 0.000000000000000000000000000001126 137.0
HKD1_k127_202265_28 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000002862 119.0
HKD1_k127_202265_29 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000003271 124.0
HKD1_k127_202265_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 509.0
HKD1_k127_202265_30 Bacterial membrane protein YfhO - - - 0.000000000000004484 90.0
HKD1_k127_202265_31 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000008723 78.0
HKD1_k127_202265_32 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000009616 64.0
HKD1_k127_202265_33 Bacterial membrane protein YfhO - - - 0.00000005533 67.0
HKD1_k127_202265_34 Bacterial membrane protein, YfhO - - - 0.0000004599 64.0
HKD1_k127_202265_35 - - - - 0.000001157 62.0
HKD1_k127_202265_36 membrane protein, required for N-linked glycosylation K07151 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016757,GO:0045229,GO:0045232,GO:0071840 2.4.99.18 0.00001147 59.0
HKD1_k127_202265_37 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00001919 58.0
HKD1_k127_202265_4 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 490.0
HKD1_k127_202265_5 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 395.0
HKD1_k127_202265_6 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 406.0
HKD1_k127_202265_7 Acts as a magnesium transporter K04767,K06213,K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 399.0
HKD1_k127_202265_8 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 405.0
HKD1_k127_202265_9 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 372.0
HKD1_k127_2028949_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 2.674e-208 666.0
HKD1_k127_2028949_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 572.0
HKD1_k127_2028949_10 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.000000000000000000000000000000000002553 141.0
HKD1_k127_2028949_11 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000004069 119.0
HKD1_k127_2028949_12 AAA ATPase domain - - - 0.0000000000002786 83.0
HKD1_k127_2028949_13 (FHA) domain - - - 0.00000000009655 75.0
HKD1_k127_2028949_14 PFAM Aminotransferase - - - 0.0001259 47.0
HKD1_k127_2028949_2 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 524.0
HKD1_k127_2028949_3 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 434.0
HKD1_k127_2028949_5 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004848 269.0
HKD1_k127_2028949_6 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008904 276.0
HKD1_k127_2028949_7 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030,K10036 - - 0.000000000000000000000000000000000000000000000000000000005936 214.0
HKD1_k127_2028949_8 COGs COG0783 DNA-binding ferritin-like protein (oxidative damage protectant) K04047 - - 0.00000000000000000000000000000000000000000000000000000001312 202.0
HKD1_k127_2028949_9 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.0000000000000000000000000000000000006616 160.0
HKD1_k127_2031461_0 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 359.0
HKD1_k127_2031461_1 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 352.0
HKD1_k127_2031461_2 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.000000000000000000000000000000000000000295 151.0
HKD1_k127_2031461_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000661 61.0
HKD1_k127_2031461_4 E-Z type HEAT repeats - - - 0.0002084 55.0
HKD1_k127_203473_0 Prolyl oligopeptidase family - - - 6.211e-270 846.0
HKD1_k127_203473_1 Protein of unknown function, DUF255 K06888 - - 4.002e-206 661.0
HKD1_k127_203473_10 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000005481 229.0
HKD1_k127_203473_11 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000001982 214.0
HKD1_k127_203473_12 LssY C-terminus - - - 0.00000000000000000000000000000000000000000000000000294 201.0
HKD1_k127_203473_13 Organic solvent tolerance protein K04744 - - 0.000000000000000000000000000000000000000000000001696 199.0
HKD1_k127_203473_14 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000002855 173.0
HKD1_k127_203473_15 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000002884 175.0
HKD1_k127_203473_16 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000002322 149.0
HKD1_k127_203473_17 4Fe-4S binding domain - - - 0.000000000000000000000000000002831 126.0
HKD1_k127_203473_18 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.0000000000000000000000006702 119.0
HKD1_k127_203473_19 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000004189 87.0
HKD1_k127_203473_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 458.0
HKD1_k127_203473_20 DSBA-like thioredoxin domain - - - 0.0000000000000001137 92.0
HKD1_k127_203473_21 protein kinase activity - - - 0.00000000000002197 87.0
HKD1_k127_203473_22 Peptidase M56 - - - 0.000000000002519 76.0
HKD1_k127_203473_23 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000002616 77.0
HKD1_k127_203473_24 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000265 70.0
HKD1_k127_203473_25 PFAM DSBA-like thioredoxin domain - - - 0.0000002941 62.0
HKD1_k127_203473_26 HEAT repeat - - - 0.00001696 57.0
HKD1_k127_203473_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 459.0
HKD1_k127_203473_4 Male sterility protein K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 414.0
HKD1_k127_203473_5 Coenzyme A transferase K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 356.0
HKD1_k127_203473_6 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 314.0
HKD1_k127_203473_7 NAD-dependent histone deacetylase activity (H3-K14 specific) K11407 - 3.5.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 337.0
HKD1_k127_203473_8 PFAM Cytochrome b b6 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 299.0
HKD1_k127_203473_9 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000001268 246.0
HKD1_k127_2064525_0 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 464.0
HKD1_k127_2064525_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000122 247.0
HKD1_k127_2064525_2 iron ion homeostasis K02012 - - 0.0000000000000000000000000000000000000000000000000000000000007048 229.0
HKD1_k127_2064525_3 Domain of unknown function (DUF4412) - - - 0.000000003682 67.0
HKD1_k127_2067417_0 ABC transporter K06020 - 3.6.3.25 6.332e-252 800.0
HKD1_k127_2067417_1 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 427.0
HKD1_k127_2067417_10 COG1405 Transcription initiation factor TFIIIB, Brf1 subunit Transcription initiation factor TFIIB - - - 0.00000000001374 70.0
HKD1_k127_2067417_11 Salt-induced outer membrane protein K07283 - - 0.000007607 58.0
HKD1_k127_2067417_2 Beta-lactamase superfamily domain K06136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000174 273.0
HKD1_k127_2067417_3 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000612 267.0
HKD1_k127_2067417_4 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000002787 247.0
HKD1_k127_2067417_5 enzyme related to lactoylglutathione lyase K06996 - - 0.000000000000000000000000000000000000000000000000000000000000000001846 235.0
HKD1_k127_2067417_6 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000001376 240.0
HKD1_k127_2067417_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000007004 213.0
HKD1_k127_2067417_8 Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000005475 216.0
HKD1_k127_2067417_9 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000007192 193.0
HKD1_k127_2071907_0 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 386.0
HKD1_k127_2071907_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000000002153 156.0
HKD1_k127_2072617_0 Type ii and iii secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001137 299.0
HKD1_k127_2077341_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.538e-222 698.0
HKD1_k127_2077341_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 528.0
HKD1_k127_2077341_2 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000003104 216.0
HKD1_k127_2093932_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 441.0
HKD1_k127_2093932_1 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000003072 278.0
HKD1_k127_2093932_2 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000003258 203.0
HKD1_k127_2093932_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000001274 177.0
HKD1_k127_2093932_4 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000002033 146.0
HKD1_k127_2093932_5 PFAM FecR protein - - - 0.0007985 50.0
HKD1_k127_2097357_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.0 1057.0
HKD1_k127_2097357_1 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 2.363e-310 961.0
HKD1_k127_2097357_10 choline dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 544.0
HKD1_k127_2097357_11 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 455.0
HKD1_k127_2097357_12 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 450.0
HKD1_k127_2097357_13 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 466.0
HKD1_k127_2097357_15 carboxylic ester hydrolase activity K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 420.0
HKD1_k127_2097357_16 Binding-protein-dependent transport system inner membrane component K02025,K10118,K10237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 428.0
HKD1_k127_2097357_17 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 377.0
HKD1_k127_2097357_18 gluconolactonase K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 385.0
HKD1_k127_2097357_19 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 357.0
HKD1_k127_2097357_2 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 1.922e-299 939.0
HKD1_k127_2097357_20 Belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 328.0
HKD1_k127_2097357_21 formate dehydrogenase K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 319.0
HKD1_k127_2097357_22 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 336.0
HKD1_k127_2097357_23 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 318.0
HKD1_k127_2097357_24 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 293.0
HKD1_k127_2097357_25 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 287.0
HKD1_k127_2097357_26 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007668 292.0
HKD1_k127_2097357_27 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000002047 248.0
HKD1_k127_2097357_28 CBS domain K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000003612 259.0
HKD1_k127_2097357_29 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000001325 227.0
HKD1_k127_2097357_3 Succinyl-CoA ligase like flavodoxin domain K09181 - - 1.056e-275 870.0
HKD1_k127_2097357_30 metallopeptidase activity K01993,K13408,K16922 - - 0.00000000000000000000000000000000000000000000000000000000000102 241.0
HKD1_k127_2097357_31 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000168 209.0
HKD1_k127_2097357_32 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000006292 209.0
HKD1_k127_2097357_33 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.00000000000000000000000000000000000000000000000003168 204.0
HKD1_k127_2097357_34 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000002597 172.0
HKD1_k127_2097357_35 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000000000000000000000000003409 154.0
HKD1_k127_2097357_36 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.00000000000000000000000000000000001071 147.0
HKD1_k127_2097357_37 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000001131 154.0
HKD1_k127_2097357_38 protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000002234 127.0
HKD1_k127_2097357_39 PFAM EAL domain - - - 0.00000000000000000000000000008696 131.0
HKD1_k127_2097357_4 Sugar (and other) transporter - - - 5.745e-246 769.0
HKD1_k127_2097357_40 Putative DNA-binding domain - - - 0.0000000000000000000000000002328 128.0
HKD1_k127_2097357_41 Thioesterase superfamily - - - 0.0000000000000000000000000008393 117.0
HKD1_k127_2097357_42 Histidine kinase - - - 0.0000000000000000000000003402 119.0
HKD1_k127_2097357_43 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.0000000000000000000003299 113.0
HKD1_k127_2097357_44 - - - - 0.0000000000000000003346 90.0
HKD1_k127_2097357_45 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000001378 89.0
HKD1_k127_2097357_46 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000004838 97.0
HKD1_k127_2097357_47 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.0000000000000001327 90.0
HKD1_k127_2097357_48 Putative DNA-binding domain - - - 0.000000000000002558 86.0
HKD1_k127_2097357_49 Redoxin - - - 0.00000000000002675 81.0
HKD1_k127_2097357_5 Extracellular solute-binding protein K02027 - - 2.07e-216 709.0
HKD1_k127_2097357_50 Belongs to the glycosyl hydrolase 13 family - - - 0.000000000005503 79.0
HKD1_k127_2097357_51 S4 RNA-binding domain K04762 - - 0.00000000034 72.0
HKD1_k127_2097357_53 Putative zinc-finger - - - 0.000000004404 60.0
HKD1_k127_2097357_54 DNA-sulfur modification-associated - - - 0.000003749 59.0
HKD1_k127_2097357_55 - - - - 0.00006457 55.0
HKD1_k127_2097357_56 - - - - 0.0009916 48.0
HKD1_k127_2097357_6 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 621.0
HKD1_k127_2097357_7 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 593.0
HKD1_k127_2097357_8 magnesium chelatase K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 574.0
HKD1_k127_2097357_9 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 550.0
HKD1_k127_2129821_0 PFAM Amidase - - - 3.877e-272 848.0
HKD1_k127_2129821_1 Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 626.0
HKD1_k127_2129821_10 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002157 256.0
HKD1_k127_2129821_11 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009476 250.0
HKD1_k127_2129821_12 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000002217 218.0
HKD1_k127_2129821_13 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000009471 197.0
HKD1_k127_2129821_14 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000000102 172.0
HKD1_k127_2129821_15 cytochrome C oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000006574 171.0
HKD1_k127_2129821_16 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000005158 175.0
HKD1_k127_2129821_17 Cytochrome c - - - 0.00000000000000000000000000000000000001551 166.0
HKD1_k127_2129821_18 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000001078 123.0
HKD1_k127_2129821_19 ferredoxin - - - 0.00000000000000000000000000351 114.0
HKD1_k127_2129821_2 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 574.0
HKD1_k127_2129821_20 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000001225 87.0
HKD1_k127_2129821_21 CBS domain K04767 - - 0.00000000000000002678 87.0
HKD1_k127_2129821_22 Cbs domain - - - 0.00000000000004718 81.0
HKD1_k127_2129821_23 - - - - 0.0000000000002416 74.0
HKD1_k127_2129821_25 Family of unknown function (DUF5335) - - - 0.00004163 55.0
HKD1_k127_2129821_3 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 526.0
HKD1_k127_2129821_4 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009979 547.0
HKD1_k127_2129821_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 402.0
HKD1_k127_2129821_6 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 374.0
HKD1_k127_2129821_7 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 349.0
HKD1_k127_2129821_8 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 324.0
HKD1_k127_2129821_9 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 297.0
HKD1_k127_2131069_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 1.043e-195 626.0
HKD1_k127_2131069_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 496.0
HKD1_k127_2131069_10 PFAM ABC transporter related K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 306.0
HKD1_k127_2131069_11 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 314.0
HKD1_k127_2131069_12 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 331.0
HKD1_k127_2131069_13 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 300.0
HKD1_k127_2131069_14 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005308 286.0
HKD1_k127_2131069_15 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000004613 260.0
HKD1_k127_2131069_16 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000002572 247.0
HKD1_k127_2131069_17 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000002835 219.0
HKD1_k127_2131069_18 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000001255 221.0
HKD1_k127_2131069_19 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000001465 209.0
HKD1_k127_2131069_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 457.0
HKD1_k127_2131069_20 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000003116 202.0
HKD1_k127_2131069_21 peptidase U61 K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000001793 194.0
HKD1_k127_2131069_22 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000009386 191.0
HKD1_k127_2131069_23 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000008331 194.0
HKD1_k127_2131069_24 Cytidylate kinase K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000008493 189.0
HKD1_k127_2131069_25 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000009394 172.0
HKD1_k127_2131069_26 Peptidase family M50 K06402 - - 0.000000000000000000000000000000000000000006368 162.0
HKD1_k127_2131069_27 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000001062 167.0
HKD1_k127_2131069_28 Stress-induced protein - - - 0.00000000000000000000000000000000000004333 166.0
HKD1_k127_2131069_29 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000004415 160.0
HKD1_k127_2131069_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 443.0
HKD1_k127_2131069_30 histone H2A K63-linked ubiquitination K10914 - - 0.00000000000000000000000000000000001268 154.0
HKD1_k127_2131069_31 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000003206 141.0
HKD1_k127_2131069_32 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000001141 126.0
HKD1_k127_2131069_33 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000004999 142.0
HKD1_k127_2131069_34 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.0000000000000000000000000008741 117.0
HKD1_k127_2131069_35 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.00000000000000000000000172 110.0
HKD1_k127_2131069_36 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.00000000000000000000001489 114.0
HKD1_k127_2131069_37 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000002547 98.0
HKD1_k127_2131069_38 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000001394 94.0
HKD1_k127_2131069_39 - - - - 0.000000000000929 78.0
HKD1_k127_2131069_4 ABC transporter K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009834 442.0
HKD1_k127_2131069_40 HEAT repeats - - - 0.00000001647 67.0
HKD1_k127_2131069_43 - - - - 0.0000261 57.0
HKD1_k127_2131069_5 TIGRFAM tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 381.0
HKD1_k127_2131069_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 377.0
HKD1_k127_2131069_7 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 364.0
HKD1_k127_2131069_8 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 349.0
HKD1_k127_2131069_9 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 328.0
HKD1_k127_2136047_0 cellulose binding - - - 0.0 1111.0
HKD1_k127_2136047_1 Protein of unknown function (DUF1214) - - - 1.081e-237 742.0
HKD1_k127_2136047_10 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000001002 242.0
HKD1_k127_2136047_11 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000002154 222.0
HKD1_k127_2136047_12 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000226 220.0
HKD1_k127_2136047_13 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.0000000000000000000000000000000000000000000000000000026 198.0
HKD1_k127_2136047_14 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000000000000005909 177.0
HKD1_k127_2136047_15 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000008697 164.0
HKD1_k127_2136047_16 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000000006002 151.0
HKD1_k127_2136047_18 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000008627 117.0
HKD1_k127_2136047_19 - - - - 0.00000000000000000000000001697 117.0
HKD1_k127_2136047_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 571.0
HKD1_k127_2136047_20 PFAM Calcium calmodulin dependent protein kinase II Association - - - 0.000000000000000000000007123 108.0
HKD1_k127_2136047_21 extracellular polysaccharide biosynthetic process K13582 - - 0.00000000000000000000001058 112.0
HKD1_k127_2136047_23 FecR protein - - - 0.000000009622 67.0
HKD1_k127_2136047_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 445.0
HKD1_k127_2136047_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 423.0
HKD1_k127_2136047_5 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 389.0
HKD1_k127_2136047_6 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 389.0
HKD1_k127_2136047_7 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 307.0
HKD1_k127_2136047_8 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 300.0
HKD1_k127_2136047_9 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004201 254.0
HKD1_k127_2138784_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 4.477e-234 734.0
HKD1_k127_2141926_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 5.493e-270 858.0
HKD1_k127_2141926_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 3.431e-213 670.0
HKD1_k127_2141926_10 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000007917 217.0
HKD1_k127_2141926_11 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000006119 203.0
HKD1_k127_2141926_12 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000000008706 204.0
HKD1_k127_2141926_13 Inner membrane component domain - - - 0.00000000000000000000000000000000000000000000000000003734 199.0
HKD1_k127_2141926_14 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000008142 185.0
HKD1_k127_2141926_15 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.000000000000000000000000000000000000000000000001248 183.0
HKD1_k127_2141926_16 Heme copper-type cytochrome quinol oxidase, subunit K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000001522 177.0
HKD1_k127_2141926_17 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000001803 174.0
HKD1_k127_2141926_18 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000002564 161.0
HKD1_k127_2141926_19 LexA-binding, inner membrane-associated putative hydrolase - - - 0.00000000000000000000000000000000000000007624 158.0
HKD1_k127_2141926_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5.268e-213 690.0
HKD1_k127_2141926_20 DinB superfamily - - - 0.0000000000000000000000000000000000000001117 167.0
HKD1_k127_2141926_21 MgtC family K07507 - - 0.0000000000000000000000000000000000000002504 154.0
HKD1_k127_2141926_22 SCO1/SenC K07152,K08976 - - 0.0000000000000000000000000000000000000005559 152.0
HKD1_k127_2141926_23 Domain of unknown function (DUF374) K02527,K09778 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000309 142.0
HKD1_k127_2141926_24 - - - - 0.000000000000000000000000000000001439 136.0
HKD1_k127_2141926_25 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000003488 138.0
HKD1_k127_2141926_26 CcmB protein K02194 - - 0.000000000000000000000000000003946 137.0
HKD1_k127_2141926_27 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000007529 113.0
HKD1_k127_2141926_28 - - - - 0.000000000000000000000001056 108.0
HKD1_k127_2141926_29 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00001151 53.0
HKD1_k127_2141926_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0033554,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 498.0
HKD1_k127_2141926_30 transport - - - 0.0003889 50.0
HKD1_k127_2141926_4 Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 471.0
HKD1_k127_2141926_5 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 442.0
HKD1_k127_2141926_6 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 418.0
HKD1_k127_2141926_7 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 343.0
HKD1_k127_2141926_8 Rnd family efflux transporter mfp subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 308.0
HKD1_k127_2141926_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000001577 246.0
HKD1_k127_2144348_0 Involved in the tonB-independent uptake of proteins - - - 3.061e-234 753.0
HKD1_k127_2144348_1 Involved in the tonB-independent uptake of proteins - - - 3.183e-211 717.0
HKD1_k127_2144348_2 Involved in the tonB-independent uptake of proteins - - - 4.333e-204 664.0
HKD1_k127_2144348_3 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 390.0
HKD1_k127_2144348_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000016 240.0
HKD1_k127_2144348_5 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000004064 122.0
HKD1_k127_2144348_6 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000000000001179 122.0
HKD1_k127_2144348_7 CGNR zinc finger - - - 0.0000000000000000000000000004615 121.0
HKD1_k127_2146630_0 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000007119 232.0
HKD1_k127_2146630_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000003097 125.0
HKD1_k127_2146630_2 PFAM Radical SAM - - - 0.00000000000006252 84.0
HKD1_k127_2146630_3 TIGRFAM DNA binding domain protein, excisionase family - - - 0.00000006845 61.0
HKD1_k127_2148457_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 3.26e-286 906.0
HKD1_k127_2155094_0 OPT oligopeptide transporter protein - - - 5.586e-297 925.0
HKD1_k127_2155094_1 metalloendopeptidase activity K01283 - 3.4.15.1 1.344e-252 792.0
HKD1_k127_2155094_10 DoxX K15977 - - 0.000000000002893 75.0
HKD1_k127_2155094_2 PFAM ribonuclease II K01147 - 3.1.13.1 2.055e-195 620.0
HKD1_k127_2155094_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 556.0
HKD1_k127_2155094_4 phosphoribosylamine-glycine ligase activity K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 509.0
HKD1_k127_2155094_5 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 386.0
HKD1_k127_2155094_6 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 350.0
HKD1_k127_2155094_7 - - - - 0.0000000000000000000000000000000004032 145.0
HKD1_k127_2155094_8 - - - - 0.0000000000000000000000000008928 121.0
HKD1_k127_2155094_9 Phosphoglycerate mutase family - - - 0.00000000000000000000003472 105.0
HKD1_k127_2163555_0 Sulfatase K01130 - 3.1.6.1 0.0 1347.0
HKD1_k127_2163555_1 Protein of unknown function (DUF3604) - - - 4.715e-320 992.0
HKD1_k127_2163555_10 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 356.0
HKD1_k127_2163555_11 4-hydroxyproline epimerase activity K01777,K12658 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.4,5.1.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 344.0
HKD1_k127_2163555_12 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 303.0
HKD1_k127_2163555_13 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 295.0
HKD1_k127_2163555_14 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000004189 234.0
HKD1_k127_2163555_15 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000001188 203.0
HKD1_k127_2163555_16 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000000000006615 178.0
HKD1_k127_2163555_17 Protein of unknown function (DUF1579) - - - 0.00000000000000000000000000000000000000000003352 168.0
HKD1_k127_2163555_18 - - - - 0.0000000000000000000000000000000000000000002119 168.0
HKD1_k127_2163555_19 ribonuclease activity - - - 0.00000000000000000000000000000000001276 143.0
HKD1_k127_2163555_2 Bacterial protein of unknown function (DUF885) - - - 6.691e-209 668.0
HKD1_k127_2163555_20 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000004324 152.0
HKD1_k127_2163555_21 Domain of unknown function (DUF4136) - - - 0.000000000000000000000001312 115.0
HKD1_k127_2163555_22 - - - - 0.0000000000000000000001482 101.0
HKD1_k127_2163555_23 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000000000496 98.0
HKD1_k127_2163555_24 - - - - 0.00000000000000000000839 93.0
HKD1_k127_2163555_25 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000008176 91.0
HKD1_k127_2163555_26 long-chain fatty acid transport protein - - - 0.00000000000009037 82.0
HKD1_k127_2163555_27 - - - - 0.000000000001169 72.0
HKD1_k127_2163555_28 Protein of unknown function (DUF3604) - - - 0.00000000001137 71.0
HKD1_k127_2163555_29 Thioredoxin-like - - - 0.000000003253 59.0
HKD1_k127_2163555_3 regulation of DNA-templated transcription, elongation - - - 3.662e-195 637.0
HKD1_k127_2163555_4 Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 626.0
HKD1_k127_2163555_5 PFAM Aldehyde dehydrogenase K13877 - 1.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 590.0
HKD1_k127_2163555_6 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 419.0
HKD1_k127_2163555_7 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 411.0
HKD1_k127_2163555_8 Belongs to the DapA family K01714,K21062 - 3.5.4.22,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 356.0
HKD1_k127_2163555_9 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 361.0
HKD1_k127_217378_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 513.0
HKD1_k127_217378_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001676 292.0
HKD1_k127_217378_2 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001301 254.0
HKD1_k127_217378_3 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001076 235.0
HKD1_k127_217378_4 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000003345 177.0
HKD1_k127_217378_5 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000002049 154.0
HKD1_k127_217378_6 Probably functions as a manganese efflux pump - - - 0.000000000000000000000002841 120.0
HKD1_k127_217378_7 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000001076 105.0
HKD1_k127_2178766_0 sensor diguanylate cyclase phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 491.0
HKD1_k127_2178766_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 467.0
HKD1_k127_2178766_2 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 378.0
HKD1_k127_2178766_3 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 338.0
HKD1_k127_2178766_4 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000001058 227.0
HKD1_k127_2178766_5 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000002118 222.0
HKD1_k127_2178766_6 TIGRFAM histidinol phosphate phosphatase HisJ family K04486 - 3.1.3.15 0.000000000000000000000000000000000000000000000000000000668 208.0
HKD1_k127_2178766_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000005545 189.0
HKD1_k127_2178766_8 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.00000000000000000000000000000000003207 136.0
HKD1_k127_2199041_0 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000001084 224.0
HKD1_k127_2199041_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000001493 180.0
HKD1_k127_2199041_2 Major Facilitator Superfamily - - - 0.0008381 44.0
HKD1_k127_2214632_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.81e-269 845.0
HKD1_k127_2214632_1 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 514.0
HKD1_k127_2214632_10 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000597 109.0
HKD1_k127_2214632_11 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000009111 106.0
HKD1_k127_2214632_12 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.00000000000000000004416 106.0
HKD1_k127_2214632_13 heat shock protein binding - - - 0.0000000000000000009651 100.0
HKD1_k127_2214632_14 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000008439 85.0
HKD1_k127_2214632_16 Domain of unknown function (DUF4126) - - - 0.00000000007692 76.0
HKD1_k127_2214632_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 463.0
HKD1_k127_2214632_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 414.0
HKD1_k127_2214632_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000004224 173.0
HKD1_k127_2214632_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000003144 169.0
HKD1_k127_2214632_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000001721 159.0
HKD1_k127_2214632_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001988 148.0
HKD1_k127_2214632_8 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000009679 136.0
HKD1_k127_2214632_9 Could be involved in septation K06412 - - 0.000000000000000000000000003485 123.0
HKD1_k127_2224320_0 AcrB/AcrD/AcrF family - - - 0.0 1107.0
HKD1_k127_2224320_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.073e-257 809.0
HKD1_k127_2224320_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000004173 92.0
HKD1_k127_2224320_11 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000001363 97.0
HKD1_k127_2224320_13 Sulfurtransferase - - - 0.000000000000002371 91.0
HKD1_k127_2224320_15 Outer membrane efflux protein - - - 0.00001602 57.0
HKD1_k127_2224320_16 amine dehydrogenase activity - - - 0.0001434 54.0
HKD1_k127_2224320_2 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 596.0
HKD1_k127_2224320_3 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 360.0
HKD1_k127_2224320_4 - - - - 0.00000000000000000000000000000000000000000000001082 190.0
HKD1_k127_2224320_5 Tautomerase enzyme - - - 0.00000000000000000000000000000000000000000002502 164.0
HKD1_k127_2224320_6 DinB family - - - 0.0000000000000000000000000000000000000009819 153.0
HKD1_k127_2224320_7 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000006667 168.0
HKD1_k127_2224320_8 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000007876 141.0
HKD1_k127_2224320_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000003525 106.0
HKD1_k127_2275317_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 6.633e-280 874.0
HKD1_k127_2275317_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 608.0
HKD1_k127_2275317_10 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 402.0
HKD1_k127_2275317_11 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 393.0
HKD1_k127_2275317_12 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 350.0
HKD1_k127_2275317_13 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 329.0
HKD1_k127_2275317_14 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 306.0
HKD1_k127_2275317_15 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 334.0
HKD1_k127_2275317_16 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001465 301.0
HKD1_k127_2275317_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001898 278.0
HKD1_k127_2275317_18 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004021 284.0
HKD1_k127_2275317_19 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004389 291.0
HKD1_k127_2275317_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 571.0
HKD1_k127_2275317_20 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007531 264.0
HKD1_k127_2275317_21 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000002232 241.0
HKD1_k127_2275317_22 PFAM peptidase M24 K01262,K01271,K01274 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000001507 236.0
HKD1_k127_2275317_23 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000006124 209.0
HKD1_k127_2275317_24 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000004187 213.0
HKD1_k127_2275317_25 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000003686 205.0
HKD1_k127_2275317_26 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001616 205.0
HKD1_k127_2275317_27 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000002215 180.0
HKD1_k127_2275317_28 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000003299 180.0
HKD1_k127_2275317_29 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000001117 175.0
HKD1_k127_2275317_3 Elongation factor G, domain IV K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 542.0
HKD1_k127_2275317_30 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000004954 175.0
HKD1_k127_2275317_31 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000006854 171.0
HKD1_k127_2275317_32 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000008812 161.0
HKD1_k127_2275317_33 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000001512 153.0
HKD1_k127_2275317_34 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000008353 150.0
HKD1_k127_2275317_35 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000012 136.0
HKD1_k127_2275317_36 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000003459 139.0
HKD1_k127_2275317_37 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000000000007673 142.0
HKD1_k127_2275317_38 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000003567 132.0
HKD1_k127_2275317_39 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000003264 126.0
HKD1_k127_2275317_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 546.0
HKD1_k127_2275317_40 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000001328 109.0
HKD1_k127_2275317_41 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001958 106.0
HKD1_k127_2275317_42 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001355 108.0
HKD1_k127_2275317_43 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000001474 103.0
HKD1_k127_2275317_44 Peptidase MA superfamily - - - 0.00000000000000000000709 109.0
HKD1_k127_2275317_45 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000002011 89.0
HKD1_k127_2275317_46 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000114 85.0
HKD1_k127_2275317_47 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000015 93.0
HKD1_k127_2275317_48 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000277 69.0
HKD1_k127_2275317_49 histone H2A K63-linked ubiquitination - - - 0.000000000001168 77.0
HKD1_k127_2275317_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 481.0
HKD1_k127_2275317_50 COG3710 DNA-binding winged-HTH domains - - - 0.0000000001963 70.0
HKD1_k127_2275317_51 ribosomal protein l30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000726 69.0
HKD1_k127_2275317_52 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000001273 63.0
HKD1_k127_2275317_53 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000003478 55.0
HKD1_k127_2275317_54 Antitoxin component of a toxin-antitoxin (TA) module - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.00001435 50.0
HKD1_k127_2275317_55 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0001088 53.0
HKD1_k127_2275317_56 TPR repeat - - - 0.0001673 53.0
HKD1_k127_2275317_6 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 446.0
HKD1_k127_2275317_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 437.0
HKD1_k127_2275317_8 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 449.0
HKD1_k127_2275317_9 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 411.0
HKD1_k127_228394_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 9.088e-198 625.0
HKD1_k127_228394_1 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 589.0
HKD1_k127_228394_10 Regulatory protein - - - 0.000000000000003305 82.0
HKD1_k127_228394_11 Domain of unknown function (DUF309) K09763 - - 0.00000000000001955 81.0
HKD1_k127_228394_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 579.0
HKD1_k127_228394_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 568.0
HKD1_k127_228394_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 364.0
HKD1_k127_228394_5 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 334.0
HKD1_k127_228394_6 Bacterial extracellular solute-binding protein K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 316.0
HKD1_k127_228394_7 PFAM binding-protein-dependent transport systems inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001656 291.0
HKD1_k127_228394_8 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000261 274.0
HKD1_k127_228394_9 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000005638 103.0
HKD1_k127_2295229_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 544.0
HKD1_k127_2295229_1 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 417.0
HKD1_k127_2295229_10 - - - - 0.000000000000000000001603 101.0
HKD1_k127_2295229_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001962 266.0
HKD1_k127_2295229_3 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000000000000000000003663 217.0
HKD1_k127_2295229_4 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000001872 171.0
HKD1_k127_2295229_5 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000001151 151.0
HKD1_k127_2295229_6 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000003195 144.0
HKD1_k127_2295229_7 SnoaL-like domain - - - 0.000000000000000000000000000000004216 139.0
HKD1_k127_2295229_8 enzyme binding K00567,K07443 - 2.1.1.63 0.000000000000000000000000000001316 129.0
HKD1_k127_2295229_9 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000005373 108.0
HKD1_k127_2299334_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 558.0
HKD1_k127_2299334_1 amino acid K03293,K16238,K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 426.0
HKD1_k127_2299334_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 393.0
HKD1_k127_2299334_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000001591 177.0
HKD1_k127_2301047_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 403.0
HKD1_k127_2301047_1 PFAM Pyridoxal-dependent decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 402.0
HKD1_k127_2301047_10 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000002433 128.0
HKD1_k127_2301047_11 Metallo-beta-lactamase superfamily - - - 0.000000000000000003746 98.0
HKD1_k127_2301047_12 Tellurite resistance protein TerB - - - 0.000000000000000005718 89.0
HKD1_k127_2301047_13 Sortilin, neurotensin receptor 3, - - - 0.00000000000001051 87.0
HKD1_k127_2301047_14 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000323 74.0
HKD1_k127_2301047_15 Protein of unknown function (DUF2891) - - - 0.0000002018 53.0
HKD1_k127_2301047_2 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000003214 248.0
HKD1_k127_2301047_3 Amino-transferase class IV K00824,K00826 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21,2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000006272 231.0
HKD1_k127_2301047_4 PFAM response regulator receiver K07665 - - 0.0000000000000000000000000000000000000000000000000000000000874 225.0
HKD1_k127_2301047_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000005775 201.0
HKD1_k127_2301047_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000004328 186.0
HKD1_k127_2301047_7 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000002079 165.0
HKD1_k127_2301047_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000002608 144.0
HKD1_k127_2301047_9 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000001094 123.0
HKD1_k127_2320967_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 3.613e-222 700.0
HKD1_k127_2320967_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 500.0
HKD1_k127_2320967_10 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000001199 187.0
HKD1_k127_2320967_11 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000009602 173.0
HKD1_k127_2320967_12 Tfp pilus assembly protein tip-associated adhesin PilY1 K02674 - - 0.00000000000000000000000000000001225 150.0
HKD1_k127_2320967_13 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000002266 109.0
HKD1_k127_2320967_14 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000006424 106.0
HKD1_k127_2320967_15 Biotin-requiring enzyme - - - 0.0000000000000001149 87.0
HKD1_k127_2320967_16 Peptidase M56 - - - 0.000000000002323 79.0
HKD1_k127_2320967_17 domain, Protein - - - 0.0000000005939 73.0
HKD1_k127_2320967_18 Tetratricopeptide repeat - - - 0.00000001599 68.0
HKD1_k127_2320967_19 TPR repeat - - - 0.0000001929 64.0
HKD1_k127_2320967_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 481.0
HKD1_k127_2320967_20 PilX N-terminal - - - 0.000005451 59.0
HKD1_k127_2320967_21 Type IV Pilus-assembly protein W K02672 - - 0.0001215 54.0
HKD1_k127_2320967_22 Type II transport protein GspH K08084 - - 0.0001401 51.0
HKD1_k127_2320967_23 Tetratricopeptide repeat - - - 0.000213 54.0
HKD1_k127_2320967_24 Protein of unknown function (DUF507) K09804 - - 0.0002281 47.0
HKD1_k127_2320967_3 response regulator K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 377.0
HKD1_k127_2320967_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009027 346.0
HKD1_k127_2320967_5 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 349.0
HKD1_k127_2320967_6 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 358.0
HKD1_k127_2320967_7 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 341.0
HKD1_k127_2320967_8 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000003959 216.0
HKD1_k127_2320967_9 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000001608 197.0
HKD1_k127_2342657_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 589.0
HKD1_k127_2342657_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 591.0
HKD1_k127_2342657_2 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 420.0
HKD1_k127_2342657_3 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 297.0
HKD1_k127_2342657_4 YCII-related domain - - - 0.00000000000000000000000036 110.0
HKD1_k127_2443370_0 PAS domain containing protein K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 375.0
HKD1_k127_2443370_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 314.0
HKD1_k127_2443370_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000103 118.0
HKD1_k127_2469241_0 Amidinotransferase K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 355.0
HKD1_k127_2469241_1 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 327.0
HKD1_k127_2469241_2 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 305.0
HKD1_k127_2469241_3 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000009788 198.0
HKD1_k127_2469241_4 Ferric siderophore transporter, periplasmic energy transduction protein TonB K03832 - - 0.000000001909 71.0
HKD1_k127_2469241_5 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.00001308 52.0
HKD1_k127_2497389_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 611.0
HKD1_k127_2497389_1 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 303.0
HKD1_k127_2497389_2 - - - - 0.00000000000000000000000000000000002963 140.0
HKD1_k127_2497389_3 Translation initiation factor SUI1 K03113 - - 0.0000000000000001247 83.0
HKD1_k127_251587_0 adenylosuccinate lyase K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 422.0
HKD1_k127_2523139_0 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 316.0
HKD1_k127_2523139_1 DinB superfamily K07552 - - 0.000000000000000000000000000000000000003763 167.0
HKD1_k127_2523139_2 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000002579 167.0
HKD1_k127_2523139_3 aminopeptidase N - - - 0.00000000000000000000000000000000009232 151.0
HKD1_k127_2523139_4 - - - - 0.000000000000000000000000000000007095 132.0
HKD1_k127_2523139_5 outer membrane efflux protein - - - 0.000000000000000000000000000001448 139.0
HKD1_k127_2523139_6 heme-binding sites - - - 0.0000000001003 76.0
HKD1_k127_2523139_7 Heavy-metal resistance - - - 0.000002492 57.0
HKD1_k127_2559016_0 WD40-like Beta Propeller Repeat - - - 1.012e-238 767.0
HKD1_k127_2559016_1 outer membrane efflux - - - 0.00000000000000000000326 96.0
HKD1_k127_2594426_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 351.0
HKD1_k127_2594426_1 EVE domain - - - 0.0000000000000000000000000000000000000007883 152.0
HKD1_k127_2594426_2 Glycosyl transferase 4-like domain - - - 0.0000000000000000006165 102.0
HKD1_k127_2594426_3 Protein of unknown function (DUF2911) - - - 0.000000000000000007873 96.0
HKD1_k127_2594426_4 metallopeptidase activity - - - 0.000002041 51.0
HKD1_k127_2601164_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 9.616e-272 884.0
HKD1_k127_2601164_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 392.0
HKD1_k127_2601164_10 Pas domain - - - 0.00000000000000000000000002839 118.0
HKD1_k127_2601164_11 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000002374 104.0
HKD1_k127_2601164_12 Universal stress protein family - - - 0.0000000000003462 79.0
HKD1_k127_2601164_2 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 379.0
HKD1_k127_2601164_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 390.0
HKD1_k127_2601164_4 Phosphomethylpyrimidine kinase K16370 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 312.0
HKD1_k127_2601164_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000947 283.0
HKD1_k127_2601164_6 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006192 277.0
HKD1_k127_2601164_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000002203 233.0
HKD1_k127_2601164_8 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000002054 217.0
HKD1_k127_2601164_9 PFAM CBS domain containing protein K07168 - - 0.000000000000000000000000003572 117.0
HKD1_k127_2688821_0 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000008916 236.0
HKD1_k127_2688821_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000003076 188.0
HKD1_k127_2688821_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000001373 190.0
HKD1_k127_2688821_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.0000000000000000000000000000000000000000000008028 183.0
HKD1_k127_2688821_4 AcrB/AcrD/AcrF family K15726 - - 0.0000000000000000000000000000000000000126 147.0
HKD1_k127_2688821_5 Outer membrane efflux protein K15725 - - 0.0000000000000000000000007039 119.0
HKD1_k127_2727330_0 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 380.0
HKD1_k127_2727330_1 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 322.0
HKD1_k127_2727330_2 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000298 209.0
HKD1_k127_2727330_3 - - - - 0.000000000000000000000000000000000000000002715 172.0
HKD1_k127_2727330_4 Protein of unknown function (DUF2950) - - - 0.00000000000001078 74.0
HKD1_k127_2786929_0 Voltage gated chloride channel - - - 3.689e-213 687.0
HKD1_k127_2786929_1 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 464.0
HKD1_k127_2786929_2 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 403.0
HKD1_k127_2786929_3 Iron/manganese superoxide dismutases, alpha-hairpin domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002672 274.0
HKD1_k127_2786929_4 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000005493 134.0
HKD1_k127_2786929_5 Winged helix DNA-binding domain - - - 0.0000000000000000000000000159 115.0
HKD1_k127_2819565_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 570.0
HKD1_k127_2819565_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 422.0
HKD1_k127_2819565_2 PFAM Formiminotransferase K00603 - 2.1.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 347.0
HKD1_k127_2819565_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000007374 259.0
HKD1_k127_2819565_4 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000006905 171.0
HKD1_k127_2819565_5 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000009236 146.0
HKD1_k127_2819565_6 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000003525 102.0
HKD1_k127_2819565_7 metallopeptidase activity - - - 0.0000000000005465 79.0
HKD1_k127_2893386_0 Serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 522.0
HKD1_k127_2893386_1 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 420.0
HKD1_k127_2893386_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 349.0
HKD1_k127_2893386_3 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000002596 195.0
HKD1_k127_2893386_4 Metal-dependent phosphoesterase K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000001597 189.0
HKD1_k127_2893386_5 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000008797 198.0
HKD1_k127_2893386_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000001501 141.0
HKD1_k127_2893386_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008784,GO:0009058,GO:0009059,GO:0009078,GO:0009079,GO:0009252,GO:0009273,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0019842,GO:0030170,GO:0030203,GO:0030632,GO:0034645,GO:0036094,GO:0036361,GO:0040007,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.1 0.00000000005621 65.0
HKD1_k127_2895953_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.0 1084.0
HKD1_k127_2895953_1 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 614.0
HKD1_k127_2895953_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 389.0
HKD1_k127_2895953_3 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005961 277.0
HKD1_k127_2895953_4 ABC transporter K01990,K19340 - - 0.0000000000008443 81.0
HKD1_k127_291619_0 LysM domain K13735 GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605 - 0.0000000000000000000000000000000000000000000000000000000000000000000000419 252.0
HKD1_k127_293642_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 3.548e-210 670.0
HKD1_k127_293642_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 537.0
HKD1_k127_293642_2 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 443.0
HKD1_k127_293642_3 Phosphomethylpyrimidine kinase K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000004242 249.0
HKD1_k127_293642_4 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000004985 224.0
HKD1_k127_293642_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000001779 174.0
HKD1_k127_293642_6 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000005522 158.0
HKD1_k127_293642_7 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.00000000000000000000000000000000003884 143.0
HKD1_k127_2943753_0 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 521.0
HKD1_k127_2943753_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000001435 247.0
HKD1_k127_2943753_2 His Kinase A (phosphoacceptor) domain K11527 - 2.7.13.3 0.00000000000000000000000000000000000000000001398 168.0
HKD1_k127_2943753_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000001746 95.0
HKD1_k127_2943753_4 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000008006 78.0
HKD1_k127_2962929_0 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 4.238e-221 716.0
HKD1_k127_2962929_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 580.0
HKD1_k127_2962929_2 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003014 296.0
HKD1_k127_2962929_3 DinB family - - - 0.00000000000000000000000000000000000000000000000000000006062 203.0
HKD1_k127_2962929_4 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000004994 199.0
HKD1_k127_2962929_5 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000003386 163.0
HKD1_k127_3010727_0 Acid phosphatase homologues - - - 0.0000000000000000005646 99.0
HKD1_k127_3010727_1 Histidine kinase - - - 0.00000000000000002085 83.0
HKD1_k127_3027532_0 Ammonium Transporter K03320 - - 7.478e-203 638.0
HKD1_k127_3027532_1 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000001451 200.0
HKD1_k127_3027532_2 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain K02030 - - 0.0000000000006524 72.0
HKD1_k127_3027532_3 PFAM Prolyl oligopeptidase family - - - 0.000000002294 58.0
HKD1_k127_3031288_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3.29e-216 706.0
HKD1_k127_3031288_1 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000005088 128.0
HKD1_k127_3031288_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000001332 96.0
HKD1_k127_3033897_0 Acetamidase/Formamidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 344.0
HKD1_k127_3033897_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 298.0
HKD1_k127_3033897_2 PFAM Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001883 256.0
HKD1_k127_3046808_0 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 446.0
HKD1_k127_3046808_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 336.0
HKD1_k127_3046808_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000065 235.0
HKD1_k127_3046808_3 - - - - 0.00000000000000000000000000000000000000000000000000000001071 219.0
HKD1_k127_3046808_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000002426 143.0
HKD1_k127_3046808_5 hydroperoxide reductase activity K01607 - 4.1.1.44 0.000000000000000000000000000000000592 132.0
HKD1_k127_3046808_6 - - - - 0.00000000000000000000000003479 124.0
HKD1_k127_3046808_7 Type III secretion system lipoprotein chaperone (YscW) - - - 0.00000000000000000000004486 104.0
HKD1_k127_3046808_8 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000002631 63.0
HKD1_k127_3048672_1 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 434.0
HKD1_k127_3048672_10 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000013 205.0
HKD1_k127_3048672_11 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000003993 204.0
HKD1_k127_3048672_12 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000001338 193.0
HKD1_k127_3048672_13 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000002114 179.0
HKD1_k127_3048672_14 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000001123 161.0
HKD1_k127_3048672_15 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000007056 160.0
HKD1_k127_3048672_16 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000006867 126.0
HKD1_k127_3048672_17 Protein of unknown function (DUF3175) - - - 0.000000000000000000006034 108.0
HKD1_k127_3048672_18 energy transducer activity K03832 - - 0.000000001796 70.0
HKD1_k127_3048672_2 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 356.0
HKD1_k127_3048672_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 366.0
HKD1_k127_3048672_4 Secretory lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 338.0
HKD1_k127_3048672_5 ATP-dependent DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000002986 242.0
HKD1_k127_3048672_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000007724 252.0
HKD1_k127_3048672_7 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000001082 225.0
HKD1_k127_3048672_8 Bacterial Ig-like domain (group 3) - - - 0.00000000000000000000000000000000000000000000000000000000002014 238.0
HKD1_k127_3048672_9 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000003591 209.0
HKD1_k127_306324_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 383.0
HKD1_k127_306324_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 321.0
HKD1_k127_306324_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000001162 181.0
HKD1_k127_306324_3 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000262 165.0
HKD1_k127_306324_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000001323 149.0
HKD1_k127_306324_5 Metallo-peptidase family M12 - - - 0.00000005228 66.0
HKD1_k127_3065047_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 497.0
HKD1_k127_3065047_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 366.0
HKD1_k127_3065047_10 Type III secretion system lipoprotein chaperone (YscW) - - - 0.000000000000000000000000000000001718 140.0
HKD1_k127_3065047_11 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000006808 130.0
HKD1_k127_3065047_12 Yqey-like protein K09117 - - 0.00000000000000000000000000005496 121.0
HKD1_k127_3065047_13 GIY-YIG catalytic domain K07461 - - 0.00000000000000000000000002979 111.0
HKD1_k127_3065047_14 CYTH K05873 - 4.6.1.1 0.00000000000000000000002141 112.0
HKD1_k127_3065047_15 Helix-hairpin-helix motif K02237 - - 0.0000000000000004251 85.0
HKD1_k127_3065047_16 Type II transport protein GspH K08084 - - 0.000005064 59.0
HKD1_k127_3065047_2 Elongation factor SelB winged helix 3 K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 376.0
HKD1_k127_3065047_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 317.0
HKD1_k127_3065047_4 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007972 292.0
HKD1_k127_3065047_5 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002289 286.0
HKD1_k127_3065047_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000009306 256.0
HKD1_k127_3065047_7 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001162 222.0
HKD1_k127_3065047_8 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000009821 154.0
HKD1_k127_3065047_9 PFAM Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000001998 150.0
HKD1_k127_306757_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 391.0
HKD1_k127_306757_1 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 376.0
HKD1_k127_306757_2 - - - - 0.0000000000005817 81.0
HKD1_k127_3080523_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 7.796e-232 725.0
HKD1_k127_3080523_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 523.0
HKD1_k127_3080523_10 TIGRFAM polysaccharide pyruvyl transferase CsaB - - - 0.0000000000000000000000000000000000000000007007 183.0
HKD1_k127_3080523_11 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000008472 172.0
HKD1_k127_3080523_12 arylsulfatase A - - - 0.0000000000000000000000000000000000000001163 169.0
HKD1_k127_3080523_13 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000223 156.0
HKD1_k127_3080523_14 Universal stress protein family - - - 0.000000000000000000000000000000000006578 140.0
HKD1_k127_3080523_15 zinc metalloprotease - - - 0.000000000000000000000207 113.0
HKD1_k127_3080523_16 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.000000000000004461 89.0
HKD1_k127_3080523_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 400.0
HKD1_k127_3080523_3 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 303.0
HKD1_k127_3080523_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000001295 261.0
HKD1_k127_3080523_5 Glycosyltransferase like family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000135 271.0
HKD1_k127_3080523_6 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000001749 243.0
HKD1_k127_3080523_7 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000008362 199.0
HKD1_k127_3080523_9 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000004381 179.0
HKD1_k127_3099736_0 Glycogen debranching enzyme - - - 5.97e-302 931.0
HKD1_k127_3099736_1 Fumarase C C-terminus K01744 - 4.3.1.1 9.716e-206 669.0
HKD1_k127_3099736_10 Glutaminase K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 326.0
HKD1_k127_3099736_11 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 309.0
HKD1_k127_3099736_12 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 310.0
HKD1_k127_3099736_13 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000001325 213.0
HKD1_k127_3099736_14 VIT family - - - 0.00000000000000000000000000000000000000000000000000003057 213.0
HKD1_k127_3099736_15 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000318 192.0
HKD1_k127_3099736_16 - - - - 0.0000000000000000000000000000000000000004902 166.0
HKD1_k127_3099736_17 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000002715 135.0
HKD1_k127_3099736_18 cheY-homologous receiver domain - - - 0.000000000000000000000000000007136 123.0
HKD1_k127_3099736_19 - - - - 0.0000000000000000000004721 112.0
HKD1_k127_3099736_2 Predicted Permease Membrane Region - - - 4.398e-197 629.0
HKD1_k127_3099736_20 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000003002 84.0
HKD1_k127_3099736_3 Inorganic ion transport and metabolism K03319 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 517.0
HKD1_k127_3099736_4 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 481.0
HKD1_k127_3099736_5 COG NOG10142 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 467.0
HKD1_k127_3099736_6 Belongs to the asparaginase 1 family K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 415.0
HKD1_k127_3099736_7 translation initiation factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 370.0
HKD1_k127_3099736_8 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 364.0
HKD1_k127_3099736_9 translation initiation factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 330.0
HKD1_k127_3100282_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.051e-288 910.0
HKD1_k127_3100282_1 Belongs to the ClpA ClpB family K03696 - - 2.972e-284 894.0
HKD1_k127_3100282_10 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 332.0
HKD1_k127_3100282_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 342.0
HKD1_k127_3100282_12 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 327.0
HKD1_k127_3100282_13 PFAM PfkB domain protein K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 322.0
HKD1_k127_3100282_14 Surface antigen variable number K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 329.0
HKD1_k127_3100282_15 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 311.0
HKD1_k127_3100282_16 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 322.0
HKD1_k127_3100282_17 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 304.0
HKD1_k127_3100282_18 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004234 307.0
HKD1_k127_3100282_19 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007853 285.0
HKD1_k127_3100282_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 553.0
HKD1_k127_3100282_20 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002288 272.0
HKD1_k127_3100282_21 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003125 260.0
HKD1_k127_3100282_22 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004435 270.0
HKD1_k127_3100282_23 Pfam Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007386 261.0
HKD1_k127_3100282_24 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000007904 248.0
HKD1_k127_3100282_25 SpoIVB peptidase S55 - - - 0.00000000000000000000000000000000000000000000000000000000000000002287 246.0
HKD1_k127_3100282_26 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000003978 244.0
HKD1_k127_3100282_27 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000073 241.0
HKD1_k127_3100282_28 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000009906 239.0
HKD1_k127_3100282_29 PFAM beta-lactamase domain protein K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000005744 224.0
HKD1_k127_3100282_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 528.0
HKD1_k127_3100282_30 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000001362 212.0
HKD1_k127_3100282_31 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000003585 206.0
HKD1_k127_3100282_32 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000009413 223.0
HKD1_k127_3100282_33 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000006022 194.0
HKD1_k127_3100282_34 - K07018 - - 0.000000000000000000000000000000000000000000000105 176.0
HKD1_k127_3100282_35 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372,K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000425 184.0
HKD1_k127_3100282_36 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000002606 177.0
HKD1_k127_3100282_37 PAP2 superfamily - - - 0.00000000000000000000000000000000000000008797 162.0
HKD1_k127_3100282_38 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000002344 172.0
HKD1_k127_3100282_39 NUDIX domain - - - 0.00000000000000000000000000000000000002737 151.0
HKD1_k127_3100282_4 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 436.0
HKD1_k127_3100282_40 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000002872 146.0
HKD1_k127_3100282_41 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000727 163.0
HKD1_k127_3100282_42 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000001231 143.0
HKD1_k127_3100282_43 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000002671 152.0
HKD1_k127_3100282_44 NusB family K03625 - - 0.0000000000000000000000000000001162 128.0
HKD1_k127_3100282_45 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000002885 135.0
HKD1_k127_3100282_46 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000003598 121.0
HKD1_k127_3100282_47 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000008032 120.0
HKD1_k127_3100282_48 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000001029 128.0
HKD1_k127_3100282_49 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000002537 126.0
HKD1_k127_3100282_5 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 409.0
HKD1_k127_3100282_50 Outer membrane lipoprotein - - - 0.00000000000000000000001002 117.0
HKD1_k127_3100282_51 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.00000000000000000000009535 115.0
HKD1_k127_3100282_52 Putative Fe-S cluster K00380 - 1.8.1.2 0.000000000000000000005966 101.0
HKD1_k127_3100282_53 PFAM Outer membrane K06142 - - 0.000000000000001196 87.0
HKD1_k127_3100282_54 thiolester hydrolase activity K17362 - - 0.000000000000001385 83.0
HKD1_k127_3100282_55 Ribosomal protein S20 K02968 - - 0.000000000724 63.0
HKD1_k127_3100282_56 TIGRFAM TonB K03832 - - 0.00000002623 64.0
HKD1_k127_3100282_58 PFAM Transglutaminase-like - - - 0.000009836 57.0
HKD1_k127_3100282_59 protein conserved in bacteria - - - 0.0002304 51.0
HKD1_k127_3100282_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 363.0
HKD1_k127_3100282_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 346.0
HKD1_k127_3100282_8 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 338.0
HKD1_k127_3100282_9 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 330.0
HKD1_k127_3118874_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.106e-292 922.0
HKD1_k127_3118874_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 4.177e-264 824.0
HKD1_k127_3118874_10 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000005346 130.0
HKD1_k127_3118874_11 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000001192 121.0
HKD1_k127_3118874_12 carbon dioxide binding K04653,K04654 - - 0.0000000000000000000000004908 123.0
HKD1_k127_3118874_13 Biogenesis protein - - - 0.0000000000000000000001091 112.0
HKD1_k127_3118874_14 Iron Permease K07243 - - 0.0000000000001719 77.0
HKD1_k127_3118874_15 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000009968 81.0
HKD1_k127_3118874_2 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 499.0
HKD1_k127_3118874_3 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 471.0
HKD1_k127_3118874_4 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 297.0
HKD1_k127_3118874_5 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002402 250.0
HKD1_k127_3118874_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000009483 189.0
HKD1_k127_3118874_7 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000000000004311 195.0
HKD1_k127_3118874_8 Enoyl-CoA hydratase carnithine racemase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000001068 174.0
HKD1_k127_3118874_9 Adenylylsulfate kinase K00860 - 2.7.1.25 0.0000000000000000000000000000000003412 148.0
HKD1_k127_3120547_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.393e-289 912.0
HKD1_k127_3120547_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.303e-199 642.0
HKD1_k127_3120547_2 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 421.0
HKD1_k127_3120547_3 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000202 230.0
HKD1_k127_3120547_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.000000000000000000000000000000000000000000000000000004241 196.0
HKD1_k127_3120547_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000003373 197.0
HKD1_k127_3120547_6 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000005376 96.0
HKD1_k127_3141264_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 7.33e-240 764.0
HKD1_k127_3141264_1 Amidohydrolase family - - - 1.921e-228 747.0
HKD1_k127_3141264_10 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 464.0
HKD1_k127_3141264_11 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 467.0
HKD1_k127_3141264_12 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 457.0
HKD1_k127_3141264_13 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 428.0
HKD1_k127_3141264_14 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 406.0
HKD1_k127_3141264_15 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 393.0
HKD1_k127_3141264_16 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 379.0
HKD1_k127_3141264_17 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 353.0
HKD1_k127_3141264_18 polysaccharide catabolic process K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 366.0
HKD1_k127_3141264_19 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 371.0
HKD1_k127_3141264_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 9.315e-211 687.0
HKD1_k127_3141264_20 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 352.0
HKD1_k127_3141264_21 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 347.0
HKD1_k127_3141264_22 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008817 340.0
HKD1_k127_3141264_23 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 325.0
HKD1_k127_3141264_24 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 324.0
HKD1_k127_3141264_25 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 341.0
HKD1_k127_3141264_26 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 340.0
HKD1_k127_3141264_27 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 316.0
HKD1_k127_3141264_28 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 323.0
HKD1_k127_3141264_29 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 298.0
HKD1_k127_3141264_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2.781e-210 677.0
HKD1_k127_3141264_30 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000142 289.0
HKD1_k127_3141264_31 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001062 280.0
HKD1_k127_3141264_32 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000001477 269.0
HKD1_k127_3141264_33 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000224 289.0
HKD1_k127_3141264_34 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000001315 222.0
HKD1_k127_3141264_35 LuxR family transcriptional regulator K03424 - - 0.0000000000000000000000000000000000000000000000000000000000001636 222.0
HKD1_k127_3141264_36 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000005007 215.0
HKD1_k127_3141264_37 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000004929 199.0
HKD1_k127_3141264_38 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000001607 188.0
HKD1_k127_3141264_39 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000001053 185.0
HKD1_k127_3141264_4 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 621.0
HKD1_k127_3141264_40 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000001708 181.0
HKD1_k127_3141264_41 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000001956 193.0
HKD1_k127_3141264_42 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000000001177 181.0
HKD1_k127_3141264_43 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000001833 169.0
HKD1_k127_3141264_44 SMART phosphoesterase PA-phosphatase related - - - 0.00000000000000000000000000000000000000002278 177.0
HKD1_k127_3141264_45 Methyltransferase domain - - - 0.0000000000000000000000000000000000000972 155.0
HKD1_k127_3141264_46 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000001648 144.0
HKD1_k127_3141264_47 STAS domain K04749 - - 0.000000000000000000000000000000001345 134.0
HKD1_k127_3141264_48 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000002344 142.0
HKD1_k127_3141264_49 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000006559 123.0
HKD1_k127_3141264_5 methionyl-tRNA aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 570.0
HKD1_k127_3141264_50 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000001422 123.0
HKD1_k127_3141264_51 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000003328 118.0
HKD1_k127_3141264_52 O-Antigen ligase K18814 - - 0.0000000000000000000000000003396 128.0
HKD1_k127_3141264_53 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000000000354 119.0
HKD1_k127_3141264_54 - - - - 0.00000000000000000000000002011 121.0
HKD1_k127_3141264_55 Zn peptidase - - - 0.0000000000000000000000001449 121.0
HKD1_k127_3141264_56 Zincin-like metallopeptidase - - - 0.00000000000000000000002436 113.0
HKD1_k127_3141264_57 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000003471 103.0
HKD1_k127_3141264_58 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000001122 106.0
HKD1_k127_3141264_59 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000002454 104.0
HKD1_k127_3141264_6 mRNA catabolic process K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 552.0
HKD1_k127_3141264_60 Domain of unknown function (DUF4160) - - - 0.000000000000000000006394 100.0
HKD1_k127_3141264_61 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000001232 89.0
HKD1_k127_3141264_62 Redoxin K03564 - 1.11.1.15 0.0000000000000009667 78.0
HKD1_k127_3141264_63 Protein of unknown function (DUF503) K09764 - - 0.000000000000006868 78.0
HKD1_k127_3141264_64 nuclease activity - - - 0.00000000000009841 84.0
HKD1_k127_3141264_66 Protein of unknown function (DUF2905) - - - 0.000000000009096 76.0
HKD1_k127_3141264_67 Cell division protein ZapA K09888 - - 0.00000000001721 68.0
HKD1_k127_3141264_68 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000004501 72.0
HKD1_k127_3141264_69 metallopeptidase activity - - - 0.00000001161 69.0
HKD1_k127_3141264_7 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 515.0
HKD1_k127_3141264_70 Belongs to the UPF0434 family K09791 - - 0.00000005643 58.0
HKD1_k127_3141264_71 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000142 61.0
HKD1_k127_3141264_73 TIGRFAM TonB family C-terminal domain K03832 - - 0.000008183 58.0
HKD1_k127_3141264_74 metal-dependent membrane protease K07052 - - 0.0000128 56.0
HKD1_k127_3141264_8 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 485.0
HKD1_k127_3141264_9 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 487.0
HKD1_k127_3182327_0 Sulfate permease family K03321 - - 2.347e-196 626.0
HKD1_k127_3182327_1 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 461.0
HKD1_k127_3182327_2 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00322 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 385.0
HKD1_k127_3182327_3 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000000000000000000000004121 209.0
HKD1_k127_3182327_4 Methyltransferase - - - 0.00000000000000000000000000000001618 134.0
HKD1_k127_3182327_5 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000006469 125.0
HKD1_k127_3204880_0 Flavin containing amine oxidoreductase - - - 6.949e-287 891.0
HKD1_k127_3204880_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 571.0
HKD1_k127_3204880_2 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 540.0
HKD1_k127_3204880_3 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 385.0
HKD1_k127_3204880_4 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 383.0
HKD1_k127_3204880_5 Cephalosporin hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000001375 234.0
HKD1_k127_3204880_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000005245 208.0
HKD1_k127_3205754_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 367.0
HKD1_k127_3205754_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 362.0
HKD1_k127_3205754_2 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 364.0
HKD1_k127_3205754_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890,K04566,K06878 - 6.1.1.10,6.1.1.20,6.1.1.6 0.000000000000000000000000000000000000000000001321 169.0
HKD1_k127_3205754_4 response regulator - - - 0.0000000008767 69.0
HKD1_k127_3232949_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 4.337e-214 679.0
HKD1_k127_3232949_1 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 324.0
HKD1_k127_3232949_2 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000005669 128.0
HKD1_k127_3232949_3 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000000403 112.0
HKD1_k127_3232949_4 Cupin domain - - - 0.0000000000000000227 90.0
HKD1_k127_3249699_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 563.0
HKD1_k127_3249699_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004618 295.0
HKD1_k127_3249699_2 Metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003419 279.0
HKD1_k127_3249699_3 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000002225 267.0
HKD1_k127_3249699_4 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007308 259.0
HKD1_k127_3249699_5 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000002275 203.0
HKD1_k127_3249699_6 stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000009216 137.0
HKD1_k127_3249699_7 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000001786 133.0
HKD1_k127_3249699_8 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000004855 94.0
HKD1_k127_3249699_9 Sporulation and spore germination - - - 0.000000000000005126 85.0
HKD1_k127_3270862_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.694e-266 833.0
HKD1_k127_3270862_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009658 565.0
HKD1_k127_3270862_10 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 348.0
HKD1_k127_3270862_11 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 318.0
HKD1_k127_3270862_12 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 305.0
HKD1_k127_3270862_13 synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001195 275.0
HKD1_k127_3270862_14 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000008355 251.0
HKD1_k127_3270862_15 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001156 250.0
HKD1_k127_3270862_16 PFAM glycosyl transferase family 39 K07264 - 2.4.2.43 0.00000000000000000000000000000000000000000000000000000000000000003228 243.0
HKD1_k127_3270862_17 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000003739 241.0
HKD1_k127_3270862_18 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000816 224.0
HKD1_k127_3270862_19 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000002447 207.0
HKD1_k127_3270862_2 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 496.0
HKD1_k127_3270862_20 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000006534 197.0
HKD1_k127_3270862_21 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000001929 194.0
HKD1_k127_3270862_22 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000001514 180.0
HKD1_k127_3270862_23 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000003764 181.0
HKD1_k127_3270862_24 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000001102 171.0
HKD1_k127_3270862_25 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000001155 177.0
HKD1_k127_3270862_26 WYL domain - - - 0.000000000000000000000000000000004637 145.0
HKD1_k127_3270862_27 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000002323 145.0
HKD1_k127_3270862_28 Belongs to the BshC family K22136 - - 0.00000000000000000000000000004326 136.0
HKD1_k127_3270862_29 Domain of unknown function (DUF1949) - - - 0.00000000000000000000000000006822 133.0
HKD1_k127_3270862_3 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 439.0
HKD1_k127_3270862_30 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000008426 128.0
HKD1_k127_3270862_31 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000001004 118.0
HKD1_k127_3270862_32 cell redox homeostasis - - - 0.000000000000000000007803 105.0
HKD1_k127_3270862_33 - - - - 0.000000000000000009458 93.0
HKD1_k127_3270862_34 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000001909 84.0
HKD1_k127_3270862_35 Haemolytic K08998 - - 0.000000000000000265 83.0
HKD1_k127_3270862_36 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.000000000000003403 89.0
HKD1_k127_3270862_37 Putative tRNA binding domain K06878 - - 0.000000000001478 69.0
HKD1_k127_3270862_38 Putative adhesin - - - 0.000000009872 66.0
HKD1_k127_3270862_39 - K16937 - 1.8.5.2 0.00000005752 61.0
HKD1_k127_3270862_4 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000547 423.0
HKD1_k127_3270862_40 helix_turn_helix, mercury resistance - - - 0.000007305 58.0
HKD1_k127_3270862_41 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00004851 50.0
HKD1_k127_3270862_5 Glycosyl transferase 4-like K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 420.0
HKD1_k127_3270862_6 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 414.0
HKD1_k127_3270862_7 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 389.0
HKD1_k127_3270862_8 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 362.0
HKD1_k127_3270862_9 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 366.0
HKD1_k127_3278483_0 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 423.0
HKD1_k127_3278483_1 Aminopeptidase I zinc metalloprotease (M18) K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 434.0
HKD1_k127_3318697_0 Heat shock 70 kDa protein K04043 - - 1.632e-304 943.0
HKD1_k127_3318697_1 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000008013 211.0
HKD1_k127_3318697_2 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000000002798 194.0
HKD1_k127_3318697_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000101 171.0
HKD1_k127_3318697_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000001663 148.0
HKD1_k127_3318697_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000001172 126.0
HKD1_k127_3318697_6 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000002575 122.0
HKD1_k127_3318697_7 Domain of unknown function (DUF1844) - - - 0.00000001263 64.0
HKD1_k127_3318697_8 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000001562 65.0
HKD1_k127_3318697_9 chaperone-mediated protein folding - - - 0.0002856 53.0
HKD1_k127_3328280_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 354.0
HKD1_k127_3328280_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000003487 222.0
HKD1_k127_3328280_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000043 215.0
HKD1_k127_335396_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 549.0
HKD1_k127_335396_1 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 428.0
HKD1_k127_335396_2 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 361.0
HKD1_k127_335396_3 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000000005672 173.0
HKD1_k127_335396_4 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000003183 87.0
HKD1_k127_3369676_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 403.0
HKD1_k127_3369676_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 368.0
HKD1_k127_3369676_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000009411 252.0
HKD1_k127_3369676_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.4.11.1 0.000000000000000000000000000000000298 145.0
HKD1_k127_3372572_0 MacB-like periplasmic core domain - - - 0.0 1088.0
HKD1_k127_3372572_1 - - - - 0.000000000000000000000000000000000000000000000000000000008748 208.0
HKD1_k127_3372572_2 - - - - 0.00000005794 53.0
HKD1_k127_3422802_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 5.083e-291 907.0
HKD1_k127_3422802_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 1.061e-228 722.0
HKD1_k127_3422802_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 381.0
HKD1_k127_3422802_3 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000001038 235.0
HKD1_k127_3422802_4 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000001083 215.0
HKD1_k127_3422802_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000004192 190.0
HKD1_k127_3422802_6 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000001063 199.0
HKD1_k127_3423689_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 1.646e-274 864.0
HKD1_k127_3423689_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00244,K00278 GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.3.5.4,1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 591.0
HKD1_k127_3423689_2 peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 554.0
HKD1_k127_3423689_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 315.0
HKD1_k127_3423689_4 ABC transporter permease K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000141 283.0
HKD1_k127_3423689_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000002343 264.0
HKD1_k127_3423689_6 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000004577 239.0
HKD1_k127_3423689_7 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000007856 243.0
HKD1_k127_3455781_0 PFAM Type II secretion system protein E K02652 - - 7.551e-216 683.0
HKD1_k127_3455781_1 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001208 299.0
HKD1_k127_3455781_2 ECF sigma factor K03088 - - 0.000000007253 61.0
HKD1_k127_3455781_3 PFAM Fimbrial assembly family protein K02663 - - 0.0000298 57.0
HKD1_k127_3455781_4 Pilus assembly protein K02662 - - 0.000432 51.0
HKD1_k127_3456615_0 PFAM BNR Asp-box repeat - - - 0.0 1139.0
HKD1_k127_3456615_1 aminopeptidase activity K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 439.0
HKD1_k127_3456615_2 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000002685 209.0
HKD1_k127_3456615_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.000000000000000000000000000000000001646 147.0
HKD1_k127_3456615_4 ketosteroid isomerase - - - 0.000000000000000000001021 101.0
HKD1_k127_3496227_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 479.0
HKD1_k127_3496227_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 436.0
HKD1_k127_3496227_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 396.0
HKD1_k127_3496227_3 hydrolase, CocE NonD family K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 361.0
HKD1_k127_3496227_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000007608 203.0
HKD1_k127_3496227_5 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000001145 155.0
HKD1_k127_3496227_6 Binds the 23S rRNA K02909 - - 0.00000000000000000000000001513 111.0
HKD1_k127_3496227_7 - - - - 0.00000000000000000000002112 117.0
HKD1_k127_36038_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 529.0
HKD1_k127_36038_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 373.0
HKD1_k127_36038_10 peptidyl-tyrosine sulfation - - - 0.0000000003077 72.0
HKD1_k127_36038_11 Acidic repeat-containing protein - GO:0000003,GO:0000280,GO:0000793,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006304,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0022402,GO:0022414,GO:0034641,GO:0035510,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044728,GO:0045132,GO:0046483,GO:0048285,GO:0051321,GO:0070988,GO:0071704,GO:0071840,GO:0080111,GO:0090304,GO:0098813,GO:0140013,GO:1901360,GO:1903046 - 0.00002189 53.0
HKD1_k127_36038_2 L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 352.0
HKD1_k127_36038_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000003443 259.0
HKD1_k127_36038_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000421 247.0
HKD1_k127_36038_5 spore germination - - - 0.00000000000000000000000000000000000000000000000000000001077 214.0
HKD1_k127_36038_6 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000001262 195.0
HKD1_k127_36038_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000001694 134.0
HKD1_k127_36038_8 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000563 125.0
HKD1_k127_36038_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000003321 120.0
HKD1_k127_3625046_0 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 351.0
HKD1_k127_3625046_1 Psort location Cytoplasmic, score K00008,K00060 - 1.1.1.103,1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000004559 240.0
HKD1_k127_3625046_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000003794 230.0
HKD1_k127_3625046_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000009238 229.0
HKD1_k127_3625046_4 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000006342 207.0
HKD1_k127_3625046_5 PFAM NADH ubiquinone oxidoreductase complex I intermediate-associated protein 30 - - - 0.00000000000000000000000000000000000000002542 159.0
HKD1_k127_3625046_6 - - - - 0.00000000000000002907 92.0
HKD1_k127_3625046_7 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000655 53.0
HKD1_k127_3655189_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1469.0
HKD1_k127_3655189_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 3.422e-232 732.0
HKD1_k127_3655189_10 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008509 270.0
HKD1_k127_3655189_11 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001556 267.0
HKD1_k127_3655189_12 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001142 250.0
HKD1_k127_3655189_13 deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000381 228.0
HKD1_k127_3655189_14 serine-type endopeptidase activity K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000002193 236.0
HKD1_k127_3655189_15 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000003103 223.0
HKD1_k127_3655189_16 - - - - 0.000000000000000000000000000000000000000000000000000000000002534 230.0
HKD1_k127_3655189_17 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000009642 215.0
HKD1_k127_3655189_18 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000002237 209.0
HKD1_k127_3655189_19 Histidine kinase - - - 0.000000000000000000000000000000000000000000000004091 188.0
HKD1_k127_3655189_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.466e-195 658.0
HKD1_k127_3655189_20 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000004111 187.0
HKD1_k127_3655189_21 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000000000000003222 183.0
HKD1_k127_3655189_22 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000187 176.0
HKD1_k127_3655189_23 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000004323 178.0
HKD1_k127_3655189_24 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000001053 167.0
HKD1_k127_3655189_25 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000187 150.0
HKD1_k127_3655189_26 TOBE domain - - - 0.0000000000000000000000000000002417 127.0
HKD1_k127_3655189_27 membrane-bound metal-dependent K07038 - - 0.00000000000000000000000000001293 132.0
HKD1_k127_3655189_28 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000001401 125.0
HKD1_k127_3655189_29 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - - 0.0000000000000000000000001112 124.0
HKD1_k127_3655189_3 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 534.0
HKD1_k127_3655189_30 HAD-hyrolase-like K07025 - - 0.0000000000000000000000001588 123.0
HKD1_k127_3655189_31 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000004814 118.0
HKD1_k127_3655189_32 response regulator - - - 0.000000000000003116 85.0
HKD1_k127_3655189_33 Thioesterase-like superfamily K07107 - - 0.000000000000009472 88.0
HKD1_k127_3655189_34 Forkhead associated domain - - - 0.0005129 52.0
HKD1_k127_3655189_4 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 427.0
HKD1_k127_3655189_5 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 375.0
HKD1_k127_3655189_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 360.0
HKD1_k127_3655189_7 outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 382.0
HKD1_k127_3655189_8 TOBE domain K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 329.0
HKD1_k127_3655189_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 314.0
HKD1_k127_3683048_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000001066 146.0
HKD1_k127_3683048_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000003593 137.0
HKD1_k127_3683048_2 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000009872 80.0
HKD1_k127_3691860_0 Extradiol ring-cleavage dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 331.0
HKD1_k127_3691860_1 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000009437 171.0
HKD1_k127_3698653_0 Sortilin, neurotensin receptor 3, - - - 0.0 1342.0
HKD1_k127_3698653_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 1.805e-219 693.0
HKD1_k127_3698653_10 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 379.0
HKD1_k127_3698653_11 Domain of unknown function (DUF1972) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 361.0
HKD1_k127_3698653_12 COG1879 ABC-type sugar transport system, periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 333.0
HKD1_k127_3698653_13 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000835 273.0
HKD1_k127_3698653_14 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009537 276.0
HKD1_k127_3698653_15 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000328 245.0
HKD1_k127_3698653_16 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000008243 254.0
HKD1_k127_3698653_17 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000006271 239.0
HKD1_k127_3698653_18 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000000771 221.0
HKD1_k127_3698653_19 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000001861 188.0
HKD1_k127_3698653_2 PFAM peptidase M61 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 622.0
HKD1_k127_3698653_20 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.00000000000000000000000000000000000000000000005147 177.0
HKD1_k127_3698653_21 Transposase - - - 0.0000000000000000000000000000000000000000000002475 179.0
HKD1_k127_3698653_22 KR domain K07535 - - 0.000000000000000000000000000000000000000000007005 185.0
HKD1_k127_3698653_23 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000003597 170.0
HKD1_k127_3698653_24 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000001063 171.0
HKD1_k127_3698653_25 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000004314 171.0
HKD1_k127_3698653_26 CARDB domain-containing protein,subtilase family protease - - - 0.0000000000000000000000000000000000000009628 168.0
HKD1_k127_3698653_27 - - - - 0.000000000000000000000000000000000000002132 160.0
HKD1_k127_3698653_28 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000001484 154.0
HKD1_k127_3698653_29 - - - - 0.000000000000000000000000000000000002178 147.0
HKD1_k127_3698653_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 555.0
HKD1_k127_3698653_30 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000001177 141.0
HKD1_k127_3698653_31 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000002137 136.0
HKD1_k127_3698653_32 Hfq protein - - - 0.0000000000000000000000000000008063 127.0
HKD1_k127_3698653_33 protocatechuate 3,4-dioxygenase activity K03286,K03640,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000009549 134.0
HKD1_k127_3698653_34 Glycosyl transferase, family 2 K07011 - - 0.00000000000000000000000000002162 136.0
HKD1_k127_3698653_35 esterase - - - 0.0000000000000000000000000008885 126.0
HKD1_k127_3698653_36 - - - - 0.000000000000000000000000009636 121.0
HKD1_k127_3698653_37 Copper resistance protein D K07245 - - 0.0000000000000000000022 104.0
HKD1_k127_3698653_38 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000000001341 90.0
HKD1_k127_3698653_4 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 567.0
HKD1_k127_3698653_40 peptidase inhibitor activity - - - 0.0000000000005727 81.0
HKD1_k127_3698653_42 cellulose binding - - - 0.00000015 64.0
HKD1_k127_3698653_44 - - - - 0.00003759 52.0
HKD1_k127_3698653_5 Belongs to the ribulokinase family K00853 - 2.7.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 568.0
HKD1_k127_3698653_6 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 451.0
HKD1_k127_3698653_7 ABC transporter K10562 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 415.0
HKD1_k127_3698653_8 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 396.0
HKD1_k127_3698653_9 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 399.0
HKD1_k127_3709528_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 1.117e-249 782.0
HKD1_k127_3709528_1 PFAM Na-Ca exchanger integrin-beta4 - - - 8.74e-212 715.0
HKD1_k127_3709528_10 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000000002047 190.0
HKD1_k127_3709528_11 Transport permease protein K01992,K09690 - - 0.00000000000000000000000000000000000000000001697 173.0
HKD1_k127_3709528_12 EamA-like transporter family - - - 0.0000000000000000000000000000000000002447 152.0
HKD1_k127_3709528_13 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000004904 145.0
HKD1_k127_3709528_14 Belongs to the peptidase S8 family K12287 - - 0.00000000000000000002338 108.0
HKD1_k127_3709528_15 bacterial-type flagellum-dependent cell motility K03641 - - 0.0000000000001723 86.0
HKD1_k127_3709528_17 Glycosyl transferases group 1 - - - 0.000001204 60.0
HKD1_k127_3709528_2 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 610.0
HKD1_k127_3709528_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 420.0
HKD1_k127_3709528_4 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 376.0
HKD1_k127_3709528_5 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 397.0
HKD1_k127_3709528_6 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 349.0
HKD1_k127_3709528_7 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000002938 267.0
HKD1_k127_3709528_8 domain, Protein K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000002625 250.0
HKD1_k127_3709528_9 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000003272 207.0
HKD1_k127_385682_0 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 321.0
HKD1_k127_385682_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K21624 - 4.2.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007911 282.0
HKD1_k127_385682_2 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.0000000000001222 79.0
HKD1_k127_391332_0 doubled CXXCH - - - 7.79e-212 685.0
HKD1_k127_391332_1 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 576.0
HKD1_k127_391332_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 470.0
HKD1_k127_391332_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 358.0
HKD1_k127_391332_4 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000000000000000004091 269.0
HKD1_k127_391332_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000004355 120.0
HKD1_k127_391332_6 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - 0.00000000000000000002333 102.0
HKD1_k127_3976082_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 6.011e-204 664.0
HKD1_k127_3976082_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 527.0
HKD1_k127_3976082_10 Selenocysteine-specific translation elongation factor K03833 - - 0.000000000005319 68.0
HKD1_k127_3976082_2 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 372.0
HKD1_k127_3976082_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 329.0
HKD1_k127_3976082_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000703 211.0
HKD1_k127_3976082_5 Ribonuclease H K03469 - 3.1.26.4 0.00000000000000000000000000002806 121.0
HKD1_k127_3976082_6 PFAM Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000003401 135.0
HKD1_k127_3976082_7 DivIVA protein K04074 - - 0.00000000000000002659 88.0
HKD1_k127_3976082_8 YGGT family K02221 - - 0.000000000000002621 88.0
HKD1_k127_3976082_9 C4-type zinc ribbon domain K07164 - - 0.0000000000000292 83.0
HKD1_k127_4041297_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 322.0
HKD1_k127_4041297_1 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 320.0
HKD1_k127_4041297_2 Cyclopropane fatty acid synthase and related methyltransferases - - - 0.0000000000000000000000000000000000000000000000000000001408 211.0
HKD1_k127_4041297_3 domain protein K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000001115 189.0
HKD1_k127_4041297_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000399 198.0
HKD1_k127_4041297_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000002461 86.0
HKD1_k127_4041297_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000008709 81.0
HKD1_k127_4041297_7 general secretion pathway protein K02456,K02650 - - 0.0003791 49.0
HKD1_k127_4043411_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 1.218e-304 957.0
HKD1_k127_4043411_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.264e-245 777.0
HKD1_k127_4043411_10 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002654 293.0
HKD1_k127_4043411_11 D-isomer specific 2-hydroxyacid dehydrogenase K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000985 287.0
HKD1_k127_4043411_12 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007397 304.0
HKD1_k127_4043411_13 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000001177 247.0
HKD1_k127_4043411_14 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003407 243.0
HKD1_k127_4043411_15 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000003125 192.0
HKD1_k127_4043411_16 ECF sigma factor K03088 - - 0.00000000000000000000000000000000007589 154.0
HKD1_k127_4043411_17 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000002573 136.0
HKD1_k127_4043411_18 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000003068 125.0
HKD1_k127_4043411_19 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000001047 121.0
HKD1_k127_4043411_2 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 587.0
HKD1_k127_4043411_20 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000004086 93.0
HKD1_k127_4043411_21 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000012 102.0
HKD1_k127_4043411_22 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000001493 84.0
HKD1_k127_4043411_23 repeat-containing protein - - - 0.000000000000005846 89.0
HKD1_k127_4043411_24 long-chain fatty acid transporting porin activity - - - 0.00000000000004884 80.0
HKD1_k127_4043411_25 ig-like, plexins, transcription factors - - - 0.0000000000009041 81.0
HKD1_k127_4043411_26 Roadblock/LC7 domain - - - 0.000000000009296 70.0
HKD1_k127_4043411_27 PFAM Fimbrial assembly family protein K02663 - - 0.0000000001926 70.0
HKD1_k127_4043411_29 Polymer-forming cytoskeletal - - - 0.0000003527 63.0
HKD1_k127_4043411_3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 552.0
HKD1_k127_4043411_30 Tetratricopeptide repeats - - - 0.00002731 56.0
HKD1_k127_4043411_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 430.0
HKD1_k127_4043411_5 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 409.0
HKD1_k127_4043411_6 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 382.0
HKD1_k127_4043411_7 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 367.0
HKD1_k127_4043411_8 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 338.0
HKD1_k127_4043411_9 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 333.0
HKD1_k127_4053198_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 462.0
HKD1_k127_4053198_1 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 365.0
HKD1_k127_4053198_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000007009 228.0
HKD1_k127_4053198_3 HlyD family secretion protein - - - 0.00000000001648 64.0
HKD1_k127_4086432_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 6.787e-223 717.0
HKD1_k127_4086432_1 heat shock protein binding - - - 1.317e-196 664.0
HKD1_k127_4086432_2 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 565.0
HKD1_k127_4086432_3 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 375.0
HKD1_k127_4086432_4 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000009456 239.0
HKD1_k127_4086432_5 Nucleic acid binding OB-fold tRNA helicase-type - - - 0.000000000000000000003788 97.0
HKD1_k127_4155715_0 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 332.0
HKD1_k127_4155715_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000003532 184.0
HKD1_k127_4155715_2 Protein of unknown function (DUF2950) - - - 0.000000000000000005318 96.0
HKD1_k127_4161171_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 632.0
HKD1_k127_4161171_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 548.0
HKD1_k127_4161171_10 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000000000055 251.0
HKD1_k127_4161171_11 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000000004179 250.0
HKD1_k127_4161171_12 Cadherin repeats. - - - 0.000000000000000000000000000000000000000000000000000000000000001373 245.0
HKD1_k127_4161171_13 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000008491 221.0
HKD1_k127_4161171_14 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000000125 243.0
HKD1_k127_4161171_15 Cadherin repeats. - - - 0.000000000000000000000000000000000000000000000000000000000002025 236.0
HKD1_k127_4161171_16 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000000000005893 229.0
HKD1_k127_4161171_17 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000000000000001417 205.0
HKD1_k127_4161171_18 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000007759 194.0
HKD1_k127_4161171_19 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000002089 169.0
HKD1_k127_4161171_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 562.0
HKD1_k127_4161171_20 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000005932 168.0
HKD1_k127_4161171_21 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000001113 164.0
HKD1_k127_4161171_22 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000237 160.0
HKD1_k127_4161171_23 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000045 149.0
HKD1_k127_4161171_24 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000001307 147.0
HKD1_k127_4161171_25 Metallo-peptidase family M12 - - - 0.0000000000000000000000000001027 134.0
HKD1_k127_4161171_26 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000001197 119.0
HKD1_k127_4161171_27 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000004173 132.0
HKD1_k127_4161171_28 endo-1,4-beta-xylanase activity - GO:0005575,GO:0005576 - 0.00000000000000000000005655 115.0
HKD1_k127_4161171_29 Smr domain - - - 0.0000000000000000001859 97.0
HKD1_k127_4161171_3 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 516.0
HKD1_k127_4161171_30 diguanylate cyclase - - - 0.0000000000000000007258 99.0
HKD1_k127_4161171_31 antibiotic catabolic process - - - 0.0000000000000000847 84.0
HKD1_k127_4161171_32 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.00000000000000009124 82.0
HKD1_k127_4161171_33 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000002539 87.0
HKD1_k127_4161171_34 Alpha beta K06889 - - 0.000000000000005733 87.0
HKD1_k127_4161171_35 Ferritin-like domain - - - 0.0000000000002143 83.0
HKD1_k127_4161171_36 response to oxidative stress - - - 0.000000000006533 72.0
HKD1_k127_4161171_37 - - - - 0.00000008574 59.0
HKD1_k127_4161171_38 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000002068 60.0
HKD1_k127_4161171_39 amine dehydrogenase activity - - - 0.0000006146 63.0
HKD1_k127_4161171_4 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 465.0
HKD1_k127_4161171_40 amine dehydrogenase activity - - - 0.000004417 60.0
HKD1_k127_4161171_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 305.0
HKD1_k127_4161171_6 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 307.0
HKD1_k127_4161171_7 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004982 288.0
HKD1_k127_4161171_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000002332 271.0
HKD1_k127_4161171_9 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000000000264 254.0
HKD1_k127_4170613_0 lipopolysaccharide transport K22110 - - 0.0 1249.0
HKD1_k127_4170613_1 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 6.179e-247 784.0
HKD1_k127_4170613_10 Predicted periplasmic lipoprotein (DUF2279) - - - 0.000000000000000006928 97.0
HKD1_k127_4170613_11 Domain of unknown function (DUF4136) - - - 0.00000000000000001095 90.0
HKD1_k127_4170613_12 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00008364 53.0
HKD1_k127_4170613_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.871e-207 657.0
HKD1_k127_4170613_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 559.0
HKD1_k127_4170613_4 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 331.0
HKD1_k127_4170613_5 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 316.0
HKD1_k127_4170613_6 PFAM ROK family K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 297.0
HKD1_k127_4170613_7 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001146 283.0
HKD1_k127_4170613_8 Phosphoglucose isomerase K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000002655 244.0
HKD1_k127_4170613_9 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067,K06192 - - 0.000000000000000000000000000000000001149 158.0
HKD1_k127_4179891_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000001906 121.0
HKD1_k127_4179891_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000001114 104.0
HKD1_k127_4179891_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000004961 96.0
HKD1_k127_4179891_3 regulator, PATAN and FRGAF domain-containing - - - 0.00000000000009626 83.0
HKD1_k127_4224154_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 453.0
HKD1_k127_4224154_1 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009903 351.0
HKD1_k127_4224154_2 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 332.0
HKD1_k127_4224154_3 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 309.0
HKD1_k127_4224154_4 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 304.0
HKD1_k127_4224154_5 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003773 279.0
HKD1_k127_4224154_6 Belongs to the phosphoenolpyruvate carboxykinase (ATP) family K01610 - 4.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000377 264.0
HKD1_k127_4224726_0 Involved in the tonB-independent uptake of proteins - - - 3.623e-203 664.0
HKD1_k127_4224726_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 509.0
HKD1_k127_4224726_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000002614 165.0
HKD1_k127_4224726_3 Adenylate cyclase - - - 0.00000000000009022 79.0
HKD1_k127_4224726_4 FHA domain - - - 0.0000000001388 70.0
HKD1_k127_4224726_5 Psort location CytoplasmicMembrane, score - - - 0.0004414 48.0
HKD1_k127_4227527_0 Dehydrogenase E1 component K11381 - 1.2.4.4 5.356e-292 911.0
HKD1_k127_4227527_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 402.0
HKD1_k127_4227527_2 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K00528,K02823 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000006259 161.0
HKD1_k127_4238031_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 364.0
HKD1_k127_4238031_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 326.0
HKD1_k127_4238031_10 Yip1 domain - - - 0.00000002432 64.0
HKD1_k127_4238031_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 318.0
HKD1_k127_4238031_3 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007429 281.0
HKD1_k127_4238031_4 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000001546 248.0
HKD1_k127_4238031_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000392 209.0
HKD1_k127_4238031_6 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000002076 193.0
HKD1_k127_4238031_7 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000002747 196.0
HKD1_k127_4238031_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000000000001823 162.0
HKD1_k127_4238031_9 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000002947 168.0
HKD1_k127_4256813_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 303.0
HKD1_k127_4256813_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000008479 231.0
HKD1_k127_4256813_2 Transcriptional regulatory protein, C terminal K07665 - - 0.000000002556 70.0
HKD1_k127_4263138_0 Protein of unknown function (DUF3604) - - - 1.388e-246 776.0
HKD1_k127_4263138_1 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 401.0
HKD1_k127_4263138_2 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 326.0
HKD1_k127_4263138_3 Protein of unknown function (DUF3604) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000351 273.0
HKD1_k127_4263138_4 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000002261 238.0
HKD1_k127_4263138_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.0000000000000000000000000000000000000000000001493 175.0
HKD1_k127_4263138_6 HupE / UreJ protein - - - 0.00000000000000000000000000000003989 132.0
HKD1_k127_4263138_7 Transcription factor K19687 - - 0.000000000000000000000000000001926 122.0
HKD1_k127_4263138_8 - - - - 0.000000000000000000000009336 106.0
HKD1_k127_4263138_9 Toxic component of a toxin-antitoxin (TA) module K07171 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.0000000000000000000006809 103.0
HKD1_k127_4278700_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.484e-290 913.0
HKD1_k127_4278700_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.592e-228 732.0
HKD1_k127_4278700_10 L-serine dehydratase, iron-sulfur-dependent, beta subunit K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000006956 212.0
HKD1_k127_4278700_11 Peptidase S53 propeptide K08677 - - 0.00000000000000000000000000000000000000000000000000000007633 216.0
HKD1_k127_4278700_12 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000008012 199.0
HKD1_k127_4278700_13 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000008276 216.0
HKD1_k127_4278700_14 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000002361 194.0
HKD1_k127_4278700_15 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000047 182.0
HKD1_k127_4278700_16 Transmembrane and TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000003988 185.0
HKD1_k127_4278700_17 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000002536 180.0
HKD1_k127_4278700_18 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.000000000000000000000000000003374 140.0
HKD1_k127_4278700_19 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000002067 128.0
HKD1_k127_4278700_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 356.0
HKD1_k127_4278700_20 - - - - 0.000000000000000000000003431 104.0
HKD1_k127_4278700_21 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000006621 89.0
HKD1_k127_4278700_22 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.00000000000000001838 85.0
HKD1_k127_4278700_23 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000311 89.0
HKD1_k127_4278700_24 SNARE associated Golgi protein - - - 0.000000000267 62.0
HKD1_k127_4278700_25 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.00005111 55.0
HKD1_k127_4278700_26 COG3209 Rhs family protein - - - 0.00072 52.0
HKD1_k127_4278700_3 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 315.0
HKD1_k127_4278700_4 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000398 309.0
HKD1_k127_4278700_5 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002802 280.0
HKD1_k127_4278700_6 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000002569 271.0
HKD1_k127_4278700_7 Transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001481 278.0
HKD1_k127_4278700_8 dehydratase K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000002919 249.0
HKD1_k127_4278700_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000008041 244.0
HKD1_k127_4341047_0 AcrB/AcrD/AcrF family K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001727 256.0
HKD1_k127_4341047_1 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0003884 52.0
HKD1_k127_4400867_0 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000006061 138.0
HKD1_k127_4400867_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000001691 140.0
HKD1_k127_4400867_2 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000003989 49.0
HKD1_k127_4461830_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.118e-198 639.0
HKD1_k127_4461830_1 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 396.0
HKD1_k127_4461830_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000007293 112.0
HKD1_k127_4461830_11 Sigma-70 region 2 K03088 - - 0.0000000000000000007558 103.0
HKD1_k127_4461830_13 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.000000000001075 76.0
HKD1_k127_4461830_2 7TM-HD extracellular K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 408.0
HKD1_k127_4461830_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 379.0
HKD1_k127_4461830_4 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 349.0
HKD1_k127_4461830_5 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 317.0
HKD1_k127_4461830_6 KH domain K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007525 273.0
HKD1_k127_4461830_7 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000001314 228.0
HKD1_k127_4461830_8 flavin adenine dinucleotide binding - - - 0.0000000000000000000000000000000000000000000000000000000007113 223.0
HKD1_k127_4461830_9 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000003751 218.0
HKD1_k127_4465630_0 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 402.0
HKD1_k127_4465630_1 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 328.0
HKD1_k127_4465630_2 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 306.0
HKD1_k127_4465630_3 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000001614 159.0
HKD1_k127_4465630_4 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000009356 165.0
HKD1_k127_4465630_6 Belongs to the peptidase S8 family - - - 0.00000001358 69.0
HKD1_k127_4502214_0 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000002458 242.0
HKD1_k127_4502214_1 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000003109 198.0
HKD1_k127_4502214_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00005115 51.0
HKD1_k127_4505292_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 458.0
HKD1_k127_4505292_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000001292 173.0
HKD1_k127_4505292_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000004298 159.0
HKD1_k127_4505292_3 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000001628 118.0
HKD1_k127_4505292_4 NADH dehydrogenase (quinone) activity K03934 - 1.6.5.3,1.6.99.3 0.00000000000000000000002548 115.0
HKD1_k127_4538454_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 382.0
HKD1_k127_4538454_1 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 374.0
HKD1_k127_4538454_2 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007917 337.0
HKD1_k127_4538454_3 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000000000000004773 194.0
HKD1_k127_4538454_4 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000006239 99.0
HKD1_k127_4538454_5 Oxidoreductase molybdopterin binding domain - - - 0.000000004663 68.0
HKD1_k127_4538454_6 cellulose binding - - - 0.00000002491 68.0
HKD1_k127_4538454_8 ABC transporter - - - 0.0003431 49.0
HKD1_k127_458014_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 4.192e-200 648.0
HKD1_k127_458014_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 396.0
HKD1_k127_458014_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 300.0
HKD1_k127_458014_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000001464 234.0
HKD1_k127_458014_4 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000005055 126.0
HKD1_k127_4621877_0 IgA Peptidase M64 - - - 4.422e-214 671.0
HKD1_k127_4621877_1 radical SAM domain protein - - - 0.000000000000000009686 92.0
HKD1_k127_4662178_0 aerobic electron transport chain K00425 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 435.0
HKD1_k127_4662178_1 oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 326.0
HKD1_k127_4662178_10 CopG antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000000000003367 119.0
HKD1_k127_4662178_11 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000000000000000000000000001545 132.0
HKD1_k127_4662178_12 Acetyltransferase - - - 0.0000000000000000000000000001713 129.0
HKD1_k127_4662178_13 PFAM CopG domain protein DNA-binding domain protein - - - 0.0000000000000000001198 92.0
HKD1_k127_4662178_14 DoxX - - - 0.00000165 57.0
HKD1_k127_4662178_15 DNA repair protein recA homolog 1 K03553 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000005039 57.0
HKD1_k127_4662178_2 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 326.0
HKD1_k127_4662178_3 PFAM Serine threonine protein kinase-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000049 287.0
HKD1_k127_4662178_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000000000000000000000000000000000000000001084 205.0
HKD1_k127_4662178_5 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000008367 183.0
HKD1_k127_4662178_6 PIN domain - - - 0.0000000000000000000000000000000000000003151 154.0
HKD1_k127_4662178_7 NUDIX domain - - - 0.00000000000000000000000000000000000198 145.0
HKD1_k127_4662178_8 Divergent 4Fe-4S mono-cluster - - - 0.0000000000000000000000000000000006136 151.0
HKD1_k127_4662178_9 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000002461 122.0
HKD1_k127_4662789_0 Histidine Phosphotransfer domain K11527 - 2.7.13.3 2.941e-229 748.0
HKD1_k127_4662789_1 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000173 175.0
HKD1_k127_4662789_2 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000003231 163.0
HKD1_k127_4670046_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000001503 134.0
HKD1_k127_4670046_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000162 59.0
HKD1_k127_4729046_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 554.0
HKD1_k127_4729046_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 523.0
HKD1_k127_4729046_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000002486 204.0
HKD1_k127_4729046_11 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.0000000000000000000000000000000000000000000000003268 180.0
HKD1_k127_4729046_12 Transcriptional regulator - - - 0.00000000000000000000000000005473 120.0
HKD1_k127_4729046_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000003147 113.0
HKD1_k127_4729046_14 Belongs to the UPF0102 family K07460 - - 0.00000000000000000005169 99.0
HKD1_k127_4729046_15 Belongs to the P(II) protein family K04752 - - 0.00000000000000000009916 98.0
HKD1_k127_4729046_17 Putative phosphatase (DUF442) - - - 0.0000000000000002072 87.0
HKD1_k127_4729046_19 - - - - 0.000001772 52.0
HKD1_k127_4729046_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 495.0
HKD1_k127_4729046_20 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000004554 52.0
HKD1_k127_4729046_3 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 453.0
HKD1_k127_4729046_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102,K11103 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 440.0
HKD1_k127_4729046_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 303.0
HKD1_k127_4729046_6 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 289.0
HKD1_k127_4729046_7 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002748 283.0
HKD1_k127_4729046_8 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000805 236.0
HKD1_k127_4729046_9 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000004774 234.0
HKD1_k127_4738575_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 601.0
HKD1_k127_4738575_1 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 359.0
HKD1_k127_4738575_2 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000001096 226.0
HKD1_k127_47650_0 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000001514 252.0
HKD1_k127_47650_1 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000000000001124 181.0
HKD1_k127_47650_2 MOSC domain - - - 0.00000000000000000002712 92.0
HKD1_k127_47650_3 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000007549 70.0
HKD1_k127_47650_4 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000003683 68.0
HKD1_k127_4787977_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1280.0
HKD1_k127_4787977_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 566.0
HKD1_k127_4787977_10 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 328.0
HKD1_k127_4787977_11 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 306.0
HKD1_k127_4787977_12 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 325.0
HKD1_k127_4787977_13 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 294.0
HKD1_k127_4787977_14 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000005562 257.0
HKD1_k127_4787977_15 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000407 246.0
HKD1_k127_4787977_16 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000003897 260.0
HKD1_k127_4787977_17 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000005436 221.0
HKD1_k127_4787977_18 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000004001 205.0
HKD1_k127_4787977_19 - - - - 0.00000000000000000000000000000000000000000000000001315 205.0
HKD1_k127_4787977_2 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 518.0
HKD1_k127_4787977_20 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000002018 190.0
HKD1_k127_4787977_21 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000008158 180.0
HKD1_k127_4787977_22 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000004692 157.0
HKD1_k127_4787977_23 Peptidase family M23 K21472 - - 0.000000000000000000000000000000001433 141.0
HKD1_k127_4787977_24 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000008612 146.0
HKD1_k127_4787977_25 lipase activity K15349 - - 0.000000000000000000000000000002154 137.0
HKD1_k127_4787977_26 von Willebrand factor, type A - - - 0.000000000000000000000000000004385 141.0
HKD1_k127_4787977_27 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000006264 130.0
HKD1_k127_4787977_28 diguanylate cyclase - - - 0.000000000000000000000000002798 128.0
HKD1_k127_4787977_29 Belongs to the Fur family K09825 - - 0.000000000000000000000001125 108.0
HKD1_k127_4787977_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 430.0
HKD1_k127_4787977_30 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000006454 116.0
HKD1_k127_4787977_31 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.00000000000000000007797 92.0
HKD1_k127_4787977_32 - - - - 0.00000000000000002177 85.0
HKD1_k127_4787977_33 Protein of unknown function (FYDLN_acid) - - - 0.000000000001483 71.0
HKD1_k127_4787977_34 chaperone-mediated protein folding - - - 0.00000000001069 80.0
HKD1_k127_4787977_35 Tetratricopeptide repeat - - - 0.000000009466 69.0
HKD1_k127_4787977_36 ribonuclease BN K07058 - - 0.000001305 61.0
HKD1_k127_4787977_37 - - - - 0.0000123 52.0
HKD1_k127_4787977_4 Dihydroxyacetone kinase family K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 432.0
HKD1_k127_4787977_5 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 401.0
HKD1_k127_4787977_6 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 398.0
HKD1_k127_4787977_7 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 375.0
HKD1_k127_4787977_8 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 353.0
HKD1_k127_4787977_9 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 352.0
HKD1_k127_4905457_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 561.0
HKD1_k127_4905457_1 Metallo-peptidase family M12 - - - 0.000000000000000000001318 111.0
HKD1_k127_4905457_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000002219 50.0
HKD1_k127_5001662_0 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 372.0
HKD1_k127_5001662_1 Glycosyltransferase like family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 313.0
HKD1_k127_5001662_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000001458 175.0
HKD1_k127_5001662_3 O-methyltransferase - - - 0.00000000000004508 80.0
HKD1_k127_5005347_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 443.0
HKD1_k127_5005347_1 Acyl-CoA dehydrogenase, N-terminal domain K00248,K00249 - 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 400.0
HKD1_k127_5005347_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 396.0
HKD1_k127_5005347_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 325.0
HKD1_k127_5005347_4 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001062 311.0
HKD1_k127_5005347_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000002458 242.0
HKD1_k127_5005347_6 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000002041 180.0
HKD1_k127_5005347_7 peptidase S1 and S6, chymotrypsin Hap K01337 - 3.4.21.50 0.000000000000000000000000002782 128.0
HKD1_k127_5005347_9 Pyruvate phosphate dikinase - - - 0.00000005361 62.0
HKD1_k127_5058596_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 468.0
HKD1_k127_5058596_1 chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 460.0
HKD1_k127_5058596_2 PFAM Alpha beta hydrolase fold-1 - - - 0.00000000000000000000000000000000000004214 149.0
HKD1_k127_5058596_3 AhpC/TSA family - - - 0.00000000000000000000000000000000000004684 155.0
HKD1_k127_5058596_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000001366 154.0
HKD1_k127_5080178_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 4.956e-217 702.0
HKD1_k127_5080178_1 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 571.0
HKD1_k127_5080178_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 331.0
HKD1_k127_5080178_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000006078 198.0
HKD1_k127_5080178_4 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000002819 159.0
HKD1_k127_5080178_5 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000000003848 117.0
HKD1_k127_5081140_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001583 300.0
HKD1_k127_5081140_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006824 272.0
HKD1_k127_5081140_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000001741 194.0
HKD1_k127_5081140_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000009812 141.0
HKD1_k127_5081140_4 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000001394 71.0
HKD1_k127_5084753_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001457 287.0
HKD1_k127_5084753_1 Elongation factor G, domain IV K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000156 237.0
HKD1_k127_5084753_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000002776 252.0
HKD1_k127_5084753_3 - - - - 0.0004132 44.0
HKD1_k127_5088901_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 596.0
HKD1_k127_5088985_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 554.0
HKD1_k127_5088985_1 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000003055 185.0
HKD1_k127_5088985_2 CHAD - - - 0.00000000000002913 82.0
HKD1_k127_5097417_0 Oligoendopeptidase f - - - 1.492e-250 791.0
HKD1_k127_5097417_1 aminopeptidase N K01263 - 3.4.11.14 2.147e-243 779.0
HKD1_k127_5097417_10 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000899 145.0
HKD1_k127_5097417_12 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000003199 119.0
HKD1_k127_5097417_15 ABC transporter related K01990 - - 0.00001035 58.0
HKD1_k127_5097417_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 635.0
HKD1_k127_5097417_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 591.0
HKD1_k127_5097417_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 548.0
HKD1_k127_5097417_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 550.0
HKD1_k127_5097417_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 347.0
HKD1_k127_5097417_7 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 306.0
HKD1_k127_5097417_8 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000001535 217.0
HKD1_k127_5097417_9 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000001002 187.0
HKD1_k127_5105895_0 lipoprotein localization to outer membrane K02004,K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007952 269.0
HKD1_k127_5105895_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000002263 237.0
HKD1_k127_5105895_2 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.00000000000000000000000000000000001183 144.0
HKD1_k127_5105895_4 YMGG-like Gly-zipper - - - 0.0000000000000000000000000000000259 137.0
HKD1_k127_5105895_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000002589 111.0
HKD1_k127_5105895_6 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000001298 106.0
HKD1_k127_5105895_7 Serine aminopeptidase, S33 - - - 0.00000000005201 73.0
HKD1_k127_5114646_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.327e-254 801.0
HKD1_k127_5114646_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000124 289.0
HKD1_k127_5114646_2 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000005077 221.0
HKD1_k127_5114646_3 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000002725 126.0
HKD1_k127_5114646_4 TIGRFAM TonB K03832 - - 0.0000000000000000000000001359 115.0
HKD1_k127_5114646_5 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000452 109.0
HKD1_k127_5114646_6 Tetratricopeptide repeat - - - 0.0000000000000000000001386 108.0
HKD1_k127_5114646_7 oxidoreductase activity - - - 0.000000000000000000002159 109.0
HKD1_k127_5114646_8 biopolymer transport protein K03559,K03560 - - 0.0000000000000000004899 93.0
HKD1_k127_5115606_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 1.078e-278 890.0
HKD1_k127_5115606_1 regulation of translation K03530 - - 0.00000000000000000000000000000000002051 137.0
HKD1_k127_5115606_2 peptidase - - - 0.00000000000000000000000000001114 132.0
HKD1_k127_5115606_3 Thioesterase superfamily - - - 0.0000000000000000000000000002409 120.0
HKD1_k127_5135416_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000005042 242.0
HKD1_k127_5135416_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000001004 197.0
HKD1_k127_5135416_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626,K07508 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000714 175.0
HKD1_k127_5135416_3 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000002597 154.0
HKD1_k127_5135416_4 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.000005828 61.0
HKD1_k127_5146344_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 1.077e-215 680.0
HKD1_k127_5146344_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 621.0
HKD1_k127_5146344_2 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 465.0
HKD1_k127_5146344_3 PFAM ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 432.0
HKD1_k127_5146344_4 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 342.0
HKD1_k127_5146344_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000001061 218.0
HKD1_k127_5146344_6 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000002948 213.0
HKD1_k127_5146344_7 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000007446 91.0
HKD1_k127_5146344_8 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.00000000005523 76.0
HKD1_k127_5148262_0 PFAM 4Fe-4S K00184,K21308 - - 0.0 1080.0
HKD1_k127_5148262_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.947e-268 852.0
HKD1_k127_5148262_10 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 327.0
HKD1_k127_5148262_11 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 298.0
HKD1_k127_5148262_12 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 293.0
HKD1_k127_5148262_13 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000007885 282.0
HKD1_k127_5148262_14 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000003109 270.0
HKD1_k127_5148262_15 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000182 259.0
HKD1_k127_5148262_16 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001172 245.0
HKD1_k127_5148262_17 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000009142 232.0
HKD1_k127_5148262_18 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000106 236.0
HKD1_k127_5148262_19 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000007171 239.0
HKD1_k127_5148262_2 Polysulphide reductase, NrfD K00185 - - 1.916e-211 666.0
HKD1_k127_5148262_20 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000759 220.0
HKD1_k127_5148262_21 GAF domain K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000000000000003503 212.0
HKD1_k127_5148262_22 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000006376 196.0
HKD1_k127_5148262_23 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000007586 199.0
HKD1_k127_5148262_24 2Fe-2S -binding K13483 - - 0.0000000000000000000000000000000000000000000000000001836 201.0
HKD1_k127_5148262_25 Sodium:solute symporter family - - - 0.000000000000000000000000000234 130.0
HKD1_k127_5148262_26 Transglutaminase-like superfamily - - - 0.000000000000000000000000001567 129.0
HKD1_k127_5148262_27 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000006644 116.0
HKD1_k127_5148262_28 Iron-sulfur cluster insertion protein ErpA K15724 - - 0.000000000000000000000000295 111.0
HKD1_k127_5148262_29 Methyltransferase FkbM domain - - - 0.0000000000000000000000751 113.0
HKD1_k127_5148262_3 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 3.452e-200 659.0
HKD1_k127_5148262_30 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000006787 102.0
HKD1_k127_5148262_31 Peptidase M56 - - - 0.000000000000009397 86.0
HKD1_k127_5148262_32 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.00000000000001856 84.0
HKD1_k127_5148262_33 - - - - 0.00000000000008104 78.0
HKD1_k127_5148262_34 Virulence activator alpha C-term - - - 0.0000000000002239 77.0
HKD1_k127_5148262_35 - - - - 0.0000002024 63.0
HKD1_k127_5148262_36 chaperone-mediated protein folding - - - 0.0000003119 62.0
HKD1_k127_5148262_37 - - - - 0.000005669 59.0
HKD1_k127_5148262_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 406.0
HKD1_k127_5148262_5 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 384.0
HKD1_k127_5148262_6 Peptidase, M20 K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 337.0
HKD1_k127_5148262_7 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 331.0
HKD1_k127_5148262_8 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 325.0
HKD1_k127_5148262_9 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 311.0
HKD1_k127_5159651_0 PFAM ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 327.0
HKD1_k127_5159651_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000001092 183.0
HKD1_k127_5159651_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000004217 166.0
HKD1_k127_5159651_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000000009834 140.0
HKD1_k127_5159651_4 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000006195 137.0
HKD1_k127_5159651_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.0000000000000000000000552 106.0
HKD1_k127_5163071_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 5.937e-280 892.0
HKD1_k127_5163071_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 599.0
HKD1_k127_5163071_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 354.0
HKD1_k127_5163071_3 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 347.0
HKD1_k127_5163071_4 Enoyl-(Acyl carrier protein) reductase K00059,K18009 - 1.1.1.100,1.1.1.304,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008483 280.0
HKD1_k127_5163071_5 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000007547 214.0
HKD1_k127_5163071_6 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000224 181.0
HKD1_k127_5163071_7 - - - - 0.000000001916 66.0
HKD1_k127_5199900_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 453.0
HKD1_k127_5199900_1 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 419.0
HKD1_k127_5203993_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 383.0
HKD1_k127_5203993_1 TonB-dependent receptor plug K02014 - - 0.00000000000000000008369 105.0
HKD1_k127_5206125_0 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 505.0
HKD1_k127_5206125_1 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 428.0
HKD1_k127_5206125_2 TLC ATP/ADP transporter K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000005277 265.0
HKD1_k127_5206125_3 Formamidopyrimidine-DNA glycosylase N-terminal domain K05522,K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000596 226.0
HKD1_k127_5206125_4 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000006991 195.0
HKD1_k127_5206125_5 - - - - 0.00000000000000000000000000000000000000000000000001074 201.0
HKD1_k127_5206125_6 phosphoprotein phosphatase activity - - - 0.00000000000000000000000000000000000000000000002249 190.0
HKD1_k127_5206125_7 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.0000000000000000000000000000000000000009542 160.0
HKD1_k127_5206125_8 glyoxalase III activity - - - 0.000000000000000000000002097 107.0
HKD1_k127_5213807_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 521.0
HKD1_k127_5213807_1 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 435.0
HKD1_k127_5213807_2 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 415.0
HKD1_k127_5213807_3 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 400.0
HKD1_k127_5213807_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001739 282.0
HKD1_k127_5213807_5 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000001407 186.0
HKD1_k127_5213807_6 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000195 155.0
HKD1_k127_5213807_7 TspO/MBR family K05770 - - 0.0000000000000000000000000001543 132.0
HKD1_k127_5213807_8 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000003184 98.0
HKD1_k127_5213807_9 PFAM FecR protein - - - 0.000000000001548 76.0
HKD1_k127_52426_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.921e-240 752.0
HKD1_k127_52426_1 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 438.0
HKD1_k127_52426_10 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.000000000000000000000000000000000186 134.0
HKD1_k127_52426_11 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000000008498 141.0
HKD1_k127_52426_12 Antitoxin component of a toxin-antitoxin (TA) module K08591,K19159 - 2.3.1.15 0.000000000000000000000001889 116.0
HKD1_k127_52426_13 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000003915 93.0
HKD1_k127_52426_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 390.0
HKD1_k127_52426_3 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 375.0
HKD1_k127_52426_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 321.0
HKD1_k127_52426_5 Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000001548 262.0
HKD1_k127_52426_6 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000001368 218.0
HKD1_k127_52426_7 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000002896 213.0
HKD1_k127_52426_8 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000001084 179.0
HKD1_k127_52426_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000004646 142.0
HKD1_k127_5276551_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.646e-251 806.0
HKD1_k127_5276551_1 Protein kinase domain K12132 - 2.7.11.1 5.466e-238 762.0
HKD1_k127_5276551_2 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008195 299.0
HKD1_k127_527667_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 326.0
HKD1_k127_527667_1 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000001338 173.0
HKD1_k127_5302602_0 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 426.0
HKD1_k127_5302602_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001215 281.0
HKD1_k127_5302602_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000008595 222.0
HKD1_k127_5302602_3 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000004559 221.0
HKD1_k127_5302602_4 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000008413 154.0
HKD1_k127_5302602_5 Class I peptide chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000000000000009059 136.0
HKD1_k127_5302602_6 AsmA family K07289 - - 0.000000000000000005813 99.0
HKD1_k127_5302602_7 Belongs to the FPG family K05522,K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.00002399 50.0
HKD1_k127_5302602_8 Ankyrin repeat - - - 0.0008813 52.0
HKD1_k127_5335847_0 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 569.0
HKD1_k127_5335847_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 546.0
HKD1_k127_5335847_10 Peptidase family S51 K13282 - 3.4.15.6 0.000000000000000000000000000000000000000000000000000000000007674 220.0
HKD1_k127_5335847_11 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000004679 210.0
HKD1_k127_5335847_12 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000001284 147.0
HKD1_k127_5335847_13 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000002515 76.0
HKD1_k127_5335847_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000007446 80.0
HKD1_k127_5335847_15 Putative phosphatase (DUF442) - - - 0.00000000002526 72.0
HKD1_k127_5335847_17 PFAM PKD domain containing protein - - - 0.00000000005491 76.0
HKD1_k127_5335847_18 Condensation domain - - - 0.00005735 56.0
HKD1_k127_5335847_19 efflux transmembrane transporter activity - - - 0.0004799 53.0
HKD1_k127_5335847_2 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 420.0
HKD1_k127_5335847_3 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007653 415.0
HKD1_k127_5335847_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 377.0
HKD1_k127_5335847_5 Sphingolipid Delta4-desaturase (DES) K04712 - 1.14.18.5,1.14.19.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 353.0
HKD1_k127_5335847_6 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 287.0
HKD1_k127_5335847_7 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003218 285.0
HKD1_k127_5335847_8 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000000001428 247.0
HKD1_k127_5335847_9 PFAM Hly-III family protein K11068 - - 0.00000000000000000000000000000000000000000000000000000000000001098 229.0
HKD1_k127_5346058_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 584.0
HKD1_k127_5346058_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 532.0
HKD1_k127_5346058_2 Permease, YjgP YjgQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 317.0
HKD1_k127_5346058_3 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000012 132.0
HKD1_k127_5350370_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 555.0
HKD1_k127_5350370_1 cyclopropane-fatty-acyl-phospholipid synthase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 391.0
HKD1_k127_5350370_10 D-aminopeptidase K16203 - - 0.000000000000001413 80.0
HKD1_k127_5350370_2 desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 321.0
HKD1_k127_5350370_3 Alanine racemase K20757 - 4.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 303.0
HKD1_k127_5350370_4 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009978 283.0
HKD1_k127_5350370_5 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000002659 178.0
HKD1_k127_5350370_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000002598 184.0
HKD1_k127_5350370_7 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000005108 153.0
HKD1_k127_5350370_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000005075 139.0
HKD1_k127_5350370_9 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000001829 115.0
HKD1_k127_5356674_0 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 609.0
HKD1_k127_5356674_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 323.0
HKD1_k127_5356674_2 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000002013 112.0
HKD1_k127_5356674_3 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000002958 119.0
HKD1_k127_5356674_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000003724 128.0
HKD1_k127_5411303_0 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000003144 259.0
HKD1_k127_5411303_1 - K12065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009707 258.0
HKD1_k127_5411303_2 TonB-dependent Receptor Plug Domain K16092 - - 0.000000000000000000000000000000000000000000000000000001372 211.0
HKD1_k127_5411303_3 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000001077 137.0
HKD1_k127_5411303_6 - - - - 0.00000806 57.0
HKD1_k127_54456_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 427.0
HKD1_k127_54456_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000003174 258.0
HKD1_k127_54456_2 Belongs to the BI1 family K06890,K19416 - - 0.0000000000000000000000000000000000000000000000000000000001088 210.0
HKD1_k127_54456_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000002595 196.0
HKD1_k127_54456_4 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000003527 179.0
HKD1_k127_54456_5 photosynthesis - - - 0.0000000000000000000000000000000000000000001125 164.0
HKD1_k127_54456_6 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.0000000000000000000000000000000000002951 152.0
HKD1_k127_54456_7 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000001071 142.0
HKD1_k127_54456_9 Copper binding proteins, plastocyanin/azurin family - - - 0.0000006007 57.0
HKD1_k127_5458382_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000007288 254.0
HKD1_k127_5458382_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000002206 173.0
HKD1_k127_5458382_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000145 116.0
HKD1_k127_5472214_0 Endoribonuclease L-PSP - - - 7.224e-210 670.0
HKD1_k127_5472214_1 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 576.0
HKD1_k127_5472214_2 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 301.0
HKD1_k127_5472214_3 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000000000000009017 145.0
HKD1_k127_5472214_4 Amidohydrolase family - - - 0.000000000000000000000005895 104.0
HKD1_k127_5472214_5 efflux transmembrane transporter activity K02004 - - 0.00000000009301 63.0
HKD1_k127_5606610_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.174e-273 878.0
HKD1_k127_5606610_1 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 474.0
HKD1_k127_5606610_10 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 342.0
HKD1_k127_5606610_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 289.0
HKD1_k127_5606610_12 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007156 298.0
HKD1_k127_5606610_13 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000002513 243.0
HKD1_k127_5606610_14 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000005842 248.0
HKD1_k127_5606610_15 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000001767 225.0
HKD1_k127_5606610_16 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000000000000000000000000000000000000000000000000008494 231.0
HKD1_k127_5606610_17 Polymorphic membrane protein Chlamydia - - - 0.0000000000000000000000000000000000000000000000443 184.0
HKD1_k127_5606610_18 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000007892 173.0
HKD1_k127_5606610_19 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000006548 143.0
HKD1_k127_5606610_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 474.0
HKD1_k127_5606610_20 Plasmid pRiA4b ORF-3-like protein - - - 0.0000000000000000000000138 107.0
HKD1_k127_5606610_21 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000002085 87.0
HKD1_k127_5606610_22 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.0000000000004451 78.0
HKD1_k127_5606610_23 Cell division protein FtsQ K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.0000002572 61.0
HKD1_k127_5606610_24 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0000002657 57.0
HKD1_k127_5606610_25 Glycosyl hydrolases family 25 - - - 0.0000004991 63.0
HKD1_k127_5606610_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 436.0
HKD1_k127_5606610_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 425.0
HKD1_k127_5606610_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 427.0
HKD1_k127_5606610_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 418.0
HKD1_k127_5606610_7 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 415.0
HKD1_k127_5606610_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 379.0
HKD1_k127_5606610_9 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 383.0
HKD1_k127_5679777_0 ADP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 629.0
HKD1_k127_5679777_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 389.0
HKD1_k127_5679777_2 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 325.0
HKD1_k127_5679777_3 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002158 234.0
HKD1_k127_5679777_4 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000000000000000000000000000000004184 244.0
HKD1_k127_5679777_5 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000008379 137.0
HKD1_k127_5679777_6 Amino acid permease K03294 - - 0.00000000000000000000000000000004511 129.0
HKD1_k127_5679777_7 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000003197 86.0
HKD1_k127_5679777_8 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00001216 57.0
HKD1_k127_5705332_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002569 277.0
HKD1_k127_5705332_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008365 256.0
HKD1_k127_5705332_2 SMART Transcription regulator, AsnC-type K03718,K03719 - - 0.000000000000000000000000000000000000000000000212 172.0
HKD1_k127_5705332_3 DinB family - - - 0.000000000000000000000000000000000000001051 165.0
HKD1_k127_5705332_4 Beta-lactamase - - - 0.000000000000000001402 89.0
HKD1_k127_5725218_0 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 449.0
HKD1_k127_5725218_1 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000003129 244.0
HKD1_k127_5725218_2 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000151 198.0
HKD1_k127_5725218_3 iron-sulfur cluster assembly K07400 - - 0.00000000000000000000000000000000000000006475 168.0
HKD1_k127_5725218_4 PFAM glycosyl transferase family 2 K14597 - - 0.0000000000000000000000000000000000000001944 170.0
HKD1_k127_5725218_5 Tetratricopeptide repeat - - - 0.0002806 51.0
HKD1_k127_5798601_0 ABC transporter K03701 - - 5.508e-247 794.0
HKD1_k127_5798601_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 581.0
HKD1_k127_5798601_10 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 325.0
HKD1_k127_5798601_11 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006575 276.0
HKD1_k127_5798601_12 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007706 260.0
HKD1_k127_5798601_13 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000009375 252.0
HKD1_k127_5798601_14 sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000001656 229.0
HKD1_k127_5798601_15 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000001475 238.0
HKD1_k127_5798601_16 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000002574 198.0
HKD1_k127_5798601_17 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000009382 192.0
HKD1_k127_5798601_18 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000005734 164.0
HKD1_k127_5798601_19 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000327 166.0
HKD1_k127_5798601_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 515.0
HKD1_k127_5798601_20 MlaD protein K02067 - - 0.0000000000000000000000000000000000003357 155.0
HKD1_k127_5798601_21 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000001016 135.0
HKD1_k127_5798601_22 4Fe-4S single cluster domain of Ferredoxin I - - - 0.000000000000000000000000000134 124.0
HKD1_k127_5798601_23 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000001385 122.0
HKD1_k127_5798601_24 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.00000000000000000000002038 112.0
HKD1_k127_5798601_25 Domain of unknown function (DUF4340) - - - 0.000000000000000000006653 107.0
HKD1_k127_5798601_26 cytochrome c biogenesis protein, transmembrane region K04084 - 1.8.1.8 0.00000000006132 72.0
HKD1_k127_5798601_27 COG3307 Lipid A core - O-antigen ligase and related enzymes K18814 - - 0.0000003243 63.0
HKD1_k127_5798601_28 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000009916 59.0
HKD1_k127_5798601_29 - - - - 0.000001692 56.0
HKD1_k127_5798601_3 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 522.0
HKD1_k127_5798601_4 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 491.0
HKD1_k127_5798601_5 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 452.0
HKD1_k127_5798601_6 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 412.0
HKD1_k127_5798601_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 369.0
HKD1_k127_5798601_8 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008633 348.0
HKD1_k127_5798601_9 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009325 297.0
HKD1_k127_5863490_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 539.0
HKD1_k127_5863490_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000004418 266.0
HKD1_k127_5865999_0 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 606.0
HKD1_k127_5865999_1 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007474 256.0
HKD1_k127_5865999_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000003869 228.0
HKD1_k127_5865999_3 response regulator - - - 0.0000000000000000000000000000000001452 148.0
HKD1_k127_5865999_4 Glutathione peroxidase - - - 0.0000000000000000000001664 104.0
HKD1_k127_5865999_5 hydrolase, P-loop family K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000004118 98.0
HKD1_k127_5865999_6 multi-organism process K03195 - - 0.0000001499 63.0
HKD1_k127_5865999_7 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00001064 57.0
HKD1_k127_5884066_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 463.0
HKD1_k127_5884066_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002107 275.0
HKD1_k127_5947849_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 541.0
HKD1_k127_5947849_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 396.0
HKD1_k127_5947849_10 Glycosyltransferase family 87 - - - 0.0000000000000000000000005061 123.0
HKD1_k127_5947849_11 phosphotransferase related to Ser Thr protein K07102 - 2.7.1.221 0.000000000000000000000002681 114.0
HKD1_k127_5947849_12 Tetratricopeptide repeat K05807 - - 0.000000000000000000001137 109.0
HKD1_k127_5947849_13 Iron-sulfur cluster-binding domain - - - 0.000000000000000000001272 108.0
HKD1_k127_5947849_14 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000000000004872 93.0
HKD1_k127_5947849_15 Bacterial membrane protein YfhO - - - 0.000000000000002336 91.0
HKD1_k127_5947849_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002534 68.0
HKD1_k127_5947849_17 LysM domain - - - 0.000000000008372 76.0
HKD1_k127_5947849_18 Haloacid dehalogenase K17686 - 3.6.3.54 0.000000003936 70.0
HKD1_k127_5947849_19 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0005723 46.0
HKD1_k127_5947849_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 308.0
HKD1_k127_5947849_3 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001362 281.0
HKD1_k127_5947849_4 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000001153 230.0
HKD1_k127_5947849_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000001913 205.0
HKD1_k127_5947849_6 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000005122 171.0
HKD1_k127_5947849_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000001648 176.0
HKD1_k127_5947849_8 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000009659 138.0
HKD1_k127_5947849_9 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000002302 131.0
HKD1_k127_5966625_0 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 374.0
HKD1_k127_5966625_1 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K07004 - 3.4.24.40 0.0000000000000000000000000000000000125 141.0
HKD1_k127_5966625_2 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000002322 80.0
HKD1_k127_6041578_0 Insulinase (Peptidase family M16) K07263 - - 1.216e-201 637.0
HKD1_k127_6041578_1 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 568.0
HKD1_k127_6041578_10 PFAM Alpha beta hydrolase K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000134 268.0
HKD1_k127_6041578_11 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000001798 247.0
HKD1_k127_6041578_12 Pfam:DUF59 - - - 0.000000000000000000000000000000000000000000000000000003266 206.0
HKD1_k127_6041578_13 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000007272 193.0
HKD1_k127_6041578_14 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000001206 204.0
HKD1_k127_6041578_15 FeS assembly protein SufB K09014 - - 0.00000000000000000000000000000000004377 134.0
HKD1_k127_6041578_2 Peptidase, M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 525.0
HKD1_k127_6041578_3 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 432.0
HKD1_k127_6041578_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 416.0
HKD1_k127_6041578_5 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 383.0
HKD1_k127_6041578_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 372.0
HKD1_k127_6041578_7 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 334.0
HKD1_k127_6041578_8 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 323.0
HKD1_k127_6041578_9 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007384 270.0
HKD1_k127_6061071_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000001294 169.0
HKD1_k127_6061071_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000004693 153.0
HKD1_k127_6062028_0 BadF/BadG/BcrA/BcrD ATPase family K04114 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 475.0
HKD1_k127_6062028_1 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 425.0
HKD1_k127_6062028_2 ABC-2 family transporter protein K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 342.0
HKD1_k127_6062028_3 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001538 298.0
HKD1_k127_6062028_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01760 - 4.4.1.8 0.00000000000000000000000000000007192 132.0
HKD1_k127_6062028_5 methylamine metabolic process - - - 0.00000000000000000000000000006708 128.0
HKD1_k127_6062028_6 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000001154 131.0
HKD1_k127_6062028_7 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000004904 123.0
HKD1_k127_6062028_8 - - - - 0.000001225 51.0
HKD1_k127_606932_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1060.0
HKD1_k127_606932_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 3.677e-239 768.0
HKD1_k127_606932_10 Dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 404.0
HKD1_k127_606932_11 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 361.0
HKD1_k127_606932_12 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 372.0
HKD1_k127_606932_13 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 328.0
HKD1_k127_606932_14 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001417 288.0
HKD1_k127_606932_15 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008323 280.0
HKD1_k127_606932_16 CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005119 276.0
HKD1_k127_606932_17 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005018 263.0
HKD1_k127_606932_18 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000001971 243.0
HKD1_k127_606932_19 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000004734 243.0
HKD1_k127_606932_2 Heat shock 70 kDa protein K04043 - - 8.454e-238 749.0
HKD1_k127_606932_20 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000003061 235.0
HKD1_k127_606932_21 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.000000000000000000000000000000000000000000003576 182.0
HKD1_k127_606932_22 Peptidase family M23 - - - 0.00000000000000000000000000000000000000007415 164.0
HKD1_k127_606932_23 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000001876 172.0
HKD1_k127_606932_24 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000004337 170.0
HKD1_k127_606932_25 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000001472 158.0
HKD1_k127_606932_26 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000001755 145.0
HKD1_k127_606932_27 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000006782 139.0
HKD1_k127_606932_28 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000000000000000000001617 137.0
HKD1_k127_606932_29 Transglycosylase SLT domain - - - 0.00000000000000000000000000000001211 136.0
HKD1_k127_606932_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.192e-196 664.0
HKD1_k127_606932_30 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000689 128.0
HKD1_k127_606932_31 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000006354 124.0
HKD1_k127_606932_32 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000174 122.0
HKD1_k127_606932_33 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000275 98.0
HKD1_k127_606932_34 Domain of unknown function (DUF2520) - - - 0.0000000000000000004669 98.0
HKD1_k127_606932_35 RNA methyltransferase K09761 - 2.1.1.193 0.00000000000000001479 98.0
HKD1_k127_606932_36 Tetratricopeptide repeat - - - 0.00000000000000003862 89.0
HKD1_k127_606932_37 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000006098 83.0
HKD1_k127_606932_38 Domain of unknown function (DUF4445) - - - 0.0000000000000004418 81.0
HKD1_k127_606932_39 Belongs to the UPF0109 family K06960 - - 0.000004726 55.0
HKD1_k127_606932_4 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 535.0
HKD1_k127_606932_40 peptidyl-tyrosine sulfation - - - 0.00001614 57.0
HKD1_k127_606932_41 Modulates RecA activity K03565 - - 0.0001823 50.0
HKD1_k127_606932_5 Magnesium chelatase, subunit ChlI K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 495.0
HKD1_k127_606932_6 AAA ATPase, central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 484.0
HKD1_k127_606932_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 473.0
HKD1_k127_606932_8 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 421.0
HKD1_k127_606932_9 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 432.0
HKD1_k127_6082496_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 377.0
HKD1_k127_6082496_1 Molybdenum cofactor synthesis domain protein K00963,K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1,2.7.7.9 0.000000000000000000000000000000000000165 149.0
HKD1_k127_6082496_2 Regulatory protein, FmdB family - - - 0.0000000000000000006834 89.0
HKD1_k127_6127438_0 Dehydrogenase E1 component K11381 - 1.2.4.4 1.376e-320 1011.0
HKD1_k127_6127438_1 Radical SAM - - - 1.619e-234 734.0
HKD1_k127_6127438_10 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007915 222.0
HKD1_k127_6127438_11 Transcriptional regulatory protein, C terminal K07665 - - 0.000000000000000000000000000000000000000000000000000000000000002686 230.0
HKD1_k127_6127438_12 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000001697 209.0
HKD1_k127_6127438_13 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000116 188.0
HKD1_k127_6127438_14 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000001285 209.0
HKD1_k127_6127438_15 Histidine kinase K07644,K18351 - 2.7.13.3 0.000000000000000000000000000000000000000000000001072 198.0
HKD1_k127_6127438_16 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.00000000000000000000000000000000000003037 163.0
HKD1_k127_6127438_17 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000000000003172 121.0
HKD1_k127_6127438_18 PFAM response regulator receiver K07657 - - 0.000000000000000000000000003579 128.0
HKD1_k127_6127438_19 membrane - - - 0.000000000000000000000004284 115.0
HKD1_k127_6127438_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.728e-204 691.0
HKD1_k127_6127438_20 Acylphosphatase K01512 - 3.6.1.7 0.00000000000004099 84.0
HKD1_k127_6127438_21 Vitamin K epoxide reductase family - - - 0.0000000002999 63.0
HKD1_k127_6127438_22 outer membrane efflux protein - - - 0.000000002064 70.0
HKD1_k127_6127438_23 Predicted periplasmic lipoprotein (DUF2279) - - - 0.00000000325 71.0
HKD1_k127_6127438_24 Biotin-lipoyl like K02005 - - 0.000000004369 70.0
HKD1_k127_6127438_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 404.0
HKD1_k127_6127438_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 363.0
HKD1_k127_6127438_5 YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 350.0
HKD1_k127_6127438_6 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 355.0
HKD1_k127_6127438_7 TIGRFAM hopanoid biosynthesis associated protein HpnK - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001132 291.0
HKD1_k127_6127438_8 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000117 259.0
HKD1_k127_6127438_9 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000002024 245.0
HKD1_k127_6134768_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 544.0
HKD1_k127_6134768_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 530.0
HKD1_k127_6134768_10 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000002783 132.0
HKD1_k127_6134768_13 Tetratricopeptide repeat - - - 0.000148 51.0
HKD1_k127_6134768_2 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 368.0
HKD1_k127_6134768_3 dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004171 285.0
HKD1_k127_6134768_4 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000002699 270.0
HKD1_k127_6134768_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000005444 219.0
HKD1_k127_6134768_6 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000003685 212.0
HKD1_k127_6134768_7 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000005617 213.0
HKD1_k127_6134768_8 abc transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000004494 181.0
HKD1_k127_6134768_9 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000001233 147.0
HKD1_k127_6149388_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 300.0
HKD1_k127_6149388_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001076 282.0
HKD1_k127_6149388_2 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000001719 132.0
HKD1_k127_6157695_0 AcrB/AcrD/AcrF family K03296 - - 1.234e-265 833.0
HKD1_k127_6157695_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 3.44e-232 747.0
HKD1_k127_6157695_10 Protein of unknown function, DUF481 - - - 0.0000000000000000000000000000000104 149.0
HKD1_k127_6157695_11 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000001997 122.0
HKD1_k127_6157695_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 627.0
HKD1_k127_6157695_3 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 612.0
HKD1_k127_6157695_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 479.0
HKD1_k127_6157695_5 Aminotransferase K14267,K14287 - 2.6.1.17,2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 469.0
HKD1_k127_6157695_6 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 385.0
HKD1_k127_6157695_7 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 306.0
HKD1_k127_6157695_8 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003201 277.0
HKD1_k127_6157695_9 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.0000000000000000000000000000000000000003768 160.0
HKD1_k127_6162458_0 PFAM Aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 399.0
HKD1_k127_6162458_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000007618 207.0
HKD1_k127_6162458_2 thyroxine 5'-deiodinase activity K01562 GO:0003674,GO:0003824,GO:0004800,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006575,GO:0006590,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008430,GO:0009987,GO:0010817,GO:0016020,GO:0016491,GO:0018958,GO:0042403,GO:0042445,GO:0044237,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901360,GO:1901564,GO:1901615 1.21.99.4 0.000000000000000000000000000000005023 132.0
HKD1_k127_6162458_3 Peptidase family S51 K13282 - 3.4.15.6 0.00000000000000000000000000785 111.0
HKD1_k127_6162458_5 PFAM PKD domain containing protein - - - 0.0000004341 64.0
HKD1_k127_6162458_6 Predicted membrane protein (DUF2127) - - - 0.0000005022 63.0
HKD1_k127_6163388_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0 1018.0
HKD1_k127_6163388_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 576.0
HKD1_k127_6163388_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 326.0
HKD1_k127_6163388_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006599 278.0
HKD1_k127_6163388_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000005159 169.0
HKD1_k127_6225356_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 335.0
HKD1_k127_6225356_1 - - - - 0.000000007052 63.0
HKD1_k127_6229158_0 AAA domain - - - 5.53e-286 898.0
HKD1_k127_6229158_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006668 280.0
HKD1_k127_6229158_2 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000002832 242.0
HKD1_k127_6229158_3 Domain of unknown function (DUF3473) - - - 0.00000000000000000000000000000000000000001107 164.0
HKD1_k127_6229158_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000007429 171.0
HKD1_k127_6229158_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000002363 103.0
HKD1_k127_6229158_6 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000002823 86.0
HKD1_k127_6229158_7 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.000184 51.0
HKD1_k127_6243318_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 602.0
HKD1_k127_6243318_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 343.0
HKD1_k127_6243318_10 maltose O-acetyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000008619 246.0
HKD1_k127_6243318_11 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000238 228.0
HKD1_k127_6243318_12 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000003313 181.0
HKD1_k127_6243318_13 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000003412 128.0
HKD1_k127_6243318_14 Putative 2OG-Fe(II) oxygenase - - - 0.00000003033 67.0
HKD1_k127_6243318_2 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 333.0
HKD1_k127_6243318_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 323.0
HKD1_k127_6243318_4 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 316.0
HKD1_k127_6243318_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008671 299.0
HKD1_k127_6243318_6 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000002714 254.0
HKD1_k127_6243318_7 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000137 248.0
HKD1_k127_6243318_8 PFAM short-chain dehydrogenase reductase SDR - GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 - 0.00000000000000000000000000000000000000000000000000000000000000000000002461 258.0
HKD1_k127_6243318_9 ThiF family K03148,K21029 - 2.7.7.73,2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000001619 261.0
HKD1_k127_6269938_0 Belongs to the PstS family K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 406.0
HKD1_k127_6269938_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 329.0
HKD1_k127_6269938_2 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004857 298.0
HKD1_k127_6269938_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006728 295.0
HKD1_k127_6276450_0 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 298.0
HKD1_k127_6276450_1 TIGRFAM glycyl-tRNA synthetase, tetrameric type, beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009876 286.0
HKD1_k127_6278317_0 PFAM peptidase M13 K07386 - - 5.762e-214 687.0
HKD1_k127_6278317_1 CorA-like Mg2+ transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 376.0
HKD1_k127_6278317_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000002911 245.0
HKD1_k127_629820_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 367.0
HKD1_k127_629820_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 306.0
HKD1_k127_629820_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000003609 85.0
HKD1_k127_629820_11 DNA polymerase III, delta' K02340 - 2.7.7.7 0.0000000000005176 81.0
HKD1_k127_629820_12 phosphohistidine phosphatase, SixA K08296 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564 - 0.000000000006334 72.0
HKD1_k127_629820_2 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004624 246.0
HKD1_k127_629820_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000009045 248.0
HKD1_k127_629820_4 TPM domain K06872 - - 0.000000000000000000000000000000000000000000824 167.0
HKD1_k127_629820_5 TPM domain - - - 0.00000000000000000000000000000000000002149 147.0
HKD1_k127_629820_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000001042 149.0
HKD1_k127_629820_7 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000001252 134.0
HKD1_k127_629820_8 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.0000000000000000000002321 102.0
HKD1_k127_629820_9 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000009147 109.0
HKD1_k127_6301322_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000571 286.0
HKD1_k127_6301322_1 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000007043 238.0
HKD1_k127_6301322_2 Competence-damaged protein K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000006323 155.0
HKD1_k127_6301322_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000002419 148.0
HKD1_k127_6301322_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000001276 100.0
HKD1_k127_6322534_0 protein kinase activity K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 467.0
HKD1_k127_6322534_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 326.0
HKD1_k127_6371622_0 Prolyl oligopeptidase K01322 - 3.4.21.26 7.088e-232 751.0
HKD1_k127_6371622_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.359e-200 649.0
HKD1_k127_6371622_10 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 329.0
HKD1_k127_6371622_11 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 300.0
HKD1_k127_6371622_12 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003749 257.0
HKD1_k127_6371622_13 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002353 251.0
HKD1_k127_6371622_14 PFAM Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000001552 178.0
HKD1_k127_6371622_15 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000002987 181.0
HKD1_k127_6371622_16 Protein of unknown function (DUF1203) - - - 0.00000000000000000000000000000000000000001936 161.0
HKD1_k127_6371622_17 META domain K03929 - - 0.00000000000000000000000000000000000000005943 164.0
HKD1_k127_6371622_18 DinB family - - - 0.0000000000000000000000000000000000000000874 156.0
HKD1_k127_6371622_19 DinB superfamily - - - 0.000000000000000000000000000000000000001616 154.0
HKD1_k127_6371622_2 AMP-binding enzyme C-terminal domain K00666,K20034 - 6.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 618.0
HKD1_k127_6371622_20 Protein of unknown function (DUF2975) - - - 0.00000000000000000000000000000000002044 146.0
HKD1_k127_6371622_21 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.0000000000000000000000000000000003563 140.0
HKD1_k127_6371622_22 Tetratricopeptide repeat - - - 0.0000000000000000000000000000007703 134.0
HKD1_k127_6371622_23 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000001962 119.0
HKD1_k127_6371622_24 Transcriptional regulator K07727 - - 0.00000000000000000000000177 112.0
HKD1_k127_6371622_26 - - - - 0.0000000000000000002663 91.0
HKD1_k127_6371622_28 lactoylglutathione lyase activity - - - 0.000000000002266 74.0
HKD1_k127_6371622_29 SnoaL-like domain - - - 0.0000004664 58.0
HKD1_k127_6371622_3 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 617.0
HKD1_k127_6371622_30 - - - - 0.000008844 51.0
HKD1_k127_6371622_4 gluconolactonase activity K01053,K13735 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 567.0
HKD1_k127_6371622_5 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 546.0
HKD1_k127_6371622_6 Alkaline phosphatase K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 459.0
HKD1_k127_6371622_7 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 441.0
HKD1_k127_6371622_8 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 381.0
HKD1_k127_6371622_9 protein kinase activity K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 346.0
HKD1_k127_6371668_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 570.0
HKD1_k127_6371668_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 550.0
HKD1_k127_6371668_2 PFAM peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 323.0
HKD1_k127_6371668_3 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003237 281.0
HKD1_k127_6371668_4 Peptidase M56 - - - 0.00000000000001107 85.0
HKD1_k127_6377158_0 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 563.0
HKD1_k127_6377158_1 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 386.0
HKD1_k127_6377158_11 chaperone-mediated protein folding - - - 0.00000000000001533 76.0
HKD1_k127_6377158_2 PFAM NAD dependent epimerase dehydratase family K12454 - 5.1.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 359.0
HKD1_k127_6377158_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001214 289.0
HKD1_k127_6377158_4 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002161 308.0
HKD1_k127_6377158_5 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000116 231.0
HKD1_k127_6377158_6 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000001465 195.0
HKD1_k127_6377158_7 NHL repeat - - - 0.00000000000000000000000000000002398 148.0
HKD1_k127_6377158_8 PFAM NHL repeat containing protein - - - 0.000000000000000000000000001919 132.0
HKD1_k127_6706547_0 C-terminal region of aryl-sulfatase K01130 - 3.1.6.1 1.724e-299 924.0
HKD1_k127_6706547_1 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 377.0
HKD1_k127_6706547_2 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 346.0
HKD1_k127_6706547_3 wide pore channel activity K07267 - - 0.00000000000000000000000000000000000000000000000000000002671 217.0
HKD1_k127_6706547_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000001921 198.0
HKD1_k127_6706547_5 response regulator - - - 0.00000000000000000000000000004098 121.0
HKD1_k127_671692_0 MacB-like periplasmic core domain - - - 9.92e-196 639.0
HKD1_k127_671692_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 616.0
HKD1_k127_671692_2 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006845 620.0
HKD1_k127_671692_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 506.0
HKD1_k127_671692_4 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 469.0
HKD1_k127_671692_5 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 346.0
HKD1_k127_671692_6 Y_Y_Y domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 319.0
HKD1_k127_671692_7 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000007249 200.0
HKD1_k127_671692_8 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000003854 163.0
HKD1_k127_671692_9 ACT domain K09707 - - 0.0000000000000000000000000000000000006571 152.0
HKD1_k127_6760027_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.187e-239 767.0
HKD1_k127_6760027_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 562.0
HKD1_k127_6760027_10 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000002552 199.0
HKD1_k127_6760027_11 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000001035 129.0
HKD1_k127_6760027_12 Tricorn protease C1 domain K03797 - 3.4.21.102 0.000000000000000000000001657 120.0
HKD1_k127_6760027_13 Methyltransferase domain - - - 0.0000000000000000000006143 108.0
HKD1_k127_6760027_14 Cytochrome c K00406,K08906 - - 0.0000002389 62.0
HKD1_k127_6760027_15 - - - - 0.00006743 57.0
HKD1_k127_6760027_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 499.0
HKD1_k127_6760027_3 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 445.0
HKD1_k127_6760027_4 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 343.0
HKD1_k127_6760027_5 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000341 267.0
HKD1_k127_6760027_6 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002029 260.0
HKD1_k127_6760027_7 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000006121 241.0
HKD1_k127_6760027_8 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000118 224.0
HKD1_k127_6760027_9 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.000000000000000000000000000000000000000000000000000001013 205.0
HKD1_k127_6781391_0 PFAM Pyridoxal-dependent decarboxylase K01580 - 4.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 591.0
HKD1_k127_6781391_1 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 569.0
HKD1_k127_6781391_10 - - - - 0.00000000000000000000000000000000000000000000000000000007353 207.0
HKD1_k127_6781391_11 transferase activity, transferring acyl groups - - - 0.0000000000000000000000000000000000000000000000000000003212 199.0
HKD1_k127_6781391_12 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000008748 189.0
HKD1_k127_6781391_13 Haem-binding domain - - - 0.000000000000000000000000000000005043 143.0
HKD1_k127_6781391_14 PFAM Transglycosylase-associated protein - - - 0.0000000000000000000000000000005864 129.0
HKD1_k127_6781391_15 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000009117 128.0
HKD1_k127_6781391_16 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000211 137.0
HKD1_k127_6781391_17 acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000002212 123.0
HKD1_k127_6781391_18 Acetyltransferase (GNAT) family - - - 0.000000000000000000001876 106.0
HKD1_k127_6781391_19 SpoIIAA-like - - - 0.00000002036 63.0
HKD1_k127_6781391_2 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 487.0
HKD1_k127_6781391_3 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 445.0
HKD1_k127_6781391_4 Belongs to the arginase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 306.0
HKD1_k127_6781391_5 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000252 289.0
HKD1_k127_6781391_6 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000005931 228.0
HKD1_k127_6781391_7 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000001071 214.0
HKD1_k127_6781391_8 protein homotetramerization - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000004425 216.0
HKD1_k127_6781391_9 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000005642 217.0
HKD1_k127_6782529_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 4.988e-271 838.0
HKD1_k127_6782529_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 460.0
HKD1_k127_6782529_2 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007511 249.0
HKD1_k127_6782529_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000002728 130.0
HKD1_k127_6782529_4 - - - - 0.000000000000000000001203 110.0
HKD1_k127_689859_0 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 576.0
HKD1_k127_689859_1 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 520.0
HKD1_k127_689859_10 Protein of unknown function (DUF4019) - - - 0.00000000000000000000000000004725 134.0
HKD1_k127_689859_11 - - - - 0.0000000000000000000009553 111.0
HKD1_k127_689859_12 Heavy-metal resistance - - - 0.00000000002128 75.0
HKD1_k127_689859_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000001201 57.0
HKD1_k127_689859_14 mRNA catabolic process K06950 - - 0.0000002464 62.0
HKD1_k127_689859_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 531.0
HKD1_k127_689859_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 441.0
HKD1_k127_689859_4 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008885 248.0
HKD1_k127_689859_5 Oxidoreductase FAD-binding domain K02613,K07140 - - 0.000000000000000000000000000000000000000000000000000000000001461 227.0
HKD1_k127_689859_6 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000001568 187.0
HKD1_k127_689859_8 ferredoxin-NADP+ reductase activity - - - 0.0000000000000000000000000000000000000003518 163.0
HKD1_k127_689859_9 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000004243 166.0
HKD1_k127_7005345_0 benzoyl-CoA reductase K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 421.0
HKD1_k127_7005345_1 Zinc-binding dehydrogenase K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 375.0
HKD1_k127_7005345_2 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000502 192.0
HKD1_k127_7005345_3 KR domain K00059 - 1.1.1.100 0.00000000000000000003724 91.0
HKD1_k127_7053378_0 4Fe-4S single cluster domain K06937 - - 5.011e-248 781.0
HKD1_k127_7053378_1 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000003473 138.0
HKD1_k127_7064378_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1287.0
HKD1_k127_7064378_1 malic protein domain protein K00029 - 1.1.1.40 4.819e-288 915.0
HKD1_k127_7064378_10 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008436 403.0
HKD1_k127_7064378_11 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 393.0
HKD1_k127_7064378_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 377.0
HKD1_k127_7064378_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 342.0
HKD1_k127_7064378_14 LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 322.0
HKD1_k127_7064378_15 Aminoacyl-tRNA editing domain K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000002514 260.0
HKD1_k127_7064378_16 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003266 268.0
HKD1_k127_7064378_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000114 244.0
HKD1_k127_7064378_18 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000003991 241.0
HKD1_k127_7064378_19 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000008186 215.0
HKD1_k127_7064378_2 phosphoribosylamine-glycine ligase activity K01945,K01955 - 6.3.4.13,6.3.5.5 5.445e-227 708.0
HKD1_k127_7064378_20 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000002398 223.0
HKD1_k127_7064378_21 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000326 205.0
HKD1_k127_7064378_22 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000001966 196.0
HKD1_k127_7064378_23 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000008945 196.0
HKD1_k127_7064378_24 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000891 186.0
HKD1_k127_7064378_25 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000002043 194.0
HKD1_k127_7064378_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000002158 159.0
HKD1_k127_7064378_27 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000004686 168.0
HKD1_k127_7064378_28 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000004142 170.0
HKD1_k127_7064378_29 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000009303 163.0
HKD1_k127_7064378_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 593.0
HKD1_k127_7064378_30 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000002652 165.0
HKD1_k127_7064378_31 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000009433 164.0
HKD1_k127_7064378_32 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000001123 160.0
HKD1_k127_7064378_33 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.00000000000000000000000000000004442 128.0
HKD1_k127_7064378_34 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000001397 122.0
HKD1_k127_7064378_35 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000003426 118.0
HKD1_k127_7064378_36 PAS fold - - - 0.000000000000000000000000005799 121.0
HKD1_k127_7064378_37 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient K05580 - 1.6.5.3 0.00000000000000000000002901 108.0
HKD1_k127_7064378_38 - - - - 0.000000000000000000000527 112.0
HKD1_k127_7064378_39 HemY domain protein - - - 0.0000000000000000000009139 111.0
HKD1_k127_7064378_4 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 579.0
HKD1_k127_7064378_40 Protein conserved in bacteria - - - 0.00000000000000000001558 103.0
HKD1_k127_7064378_42 PFAM peptidase - - - 0.000000000000000002574 97.0
HKD1_k127_7064378_46 HemY domain protein - - - 0.0000000000000001718 93.0
HKD1_k127_7064378_47 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000005543 85.0
HKD1_k127_7064378_48 - - - - 0.00000000000008436 83.0
HKD1_k127_7064378_49 O-Antigen ligase - - - 0.00000000002204 77.0
HKD1_k127_7064378_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 561.0
HKD1_k127_7064378_50 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000003158 55.0
HKD1_k127_7064378_6 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 488.0
HKD1_k127_7064378_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 493.0
HKD1_k127_7064378_8 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 469.0
HKD1_k127_7064378_9 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 447.0
HKD1_k127_7073036_0 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 342.0
HKD1_k127_7080499_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002675 286.0
HKD1_k127_7080499_1 Surface antigen variable number - - - 0.0000000000000000000000000000000000000000000000000000000000000000004455 264.0
HKD1_k127_7080499_2 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.000000000000000000000000000000131 126.0
HKD1_k127_7080499_3 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000005747 113.0
HKD1_k127_7080499_4 Regulatory protein, FmdB family - - - 0.000000000000000006609 86.0
HKD1_k127_7124758_0 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 426.0
HKD1_k127_7124758_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 408.0
HKD1_k127_7124758_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000006232 106.0
HKD1_k127_7124758_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 378.0
HKD1_k127_7124758_3 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 341.0
HKD1_k127_7124758_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 326.0
HKD1_k127_7124758_5 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001633 283.0
HKD1_k127_7124758_6 NmrA-like family - - - 0.00000000000000000000000000000000000000003343 157.0
HKD1_k127_7124758_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000001935 161.0
HKD1_k127_7124758_8 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000009382 138.0
HKD1_k127_7124758_9 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000000005615 126.0
HKD1_k127_7141895_0 lipopolysaccharide transport K22110 - - 0.0 1420.0
HKD1_k127_7141895_1 Amylo-alpha-1,6-glucosidase - - - 1.362e-249 785.0
HKD1_k127_7141895_10 beta-lactamase - - - 0.000000000001007 73.0
HKD1_k127_7141895_2 Transposase K02557,K07484,K13924,K21471 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 569.0
HKD1_k127_7141895_3 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 538.0
HKD1_k127_7141895_4 NADH dehydrogenase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 387.0
HKD1_k127_7141895_5 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 373.0
HKD1_k127_7141895_6 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005581 269.0
HKD1_k127_7141895_7 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001488 263.0
HKD1_k127_7141895_8 Methyltransferase domain - - - 0.000000000000000000000000000000000000000006012 166.0
HKD1_k127_7141895_9 DoxX-like family K15977 - - 0.000000000000000000000000000002953 125.0
HKD1_k127_7147739_0 Serine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 438.0
HKD1_k127_7147739_1 Beta-lactamase enzyme family K07258,K17836 - 3.4.16.4,3.5.2.6 0.000000000000000000000000000000000000000486 160.0
HKD1_k127_7147739_2 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000001093 150.0
HKD1_k127_7147739_4 Membrane - - - 0.000000001133 64.0
HKD1_k127_7184878_0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 574.0
HKD1_k127_7184878_1 synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 490.0
HKD1_k127_7184878_10 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 320.0
HKD1_k127_7184878_11 alcohol dehydrogenase K18012 - 1.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 313.0
HKD1_k127_7184878_12 Tyrosine recombinase xerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007275 282.0
HKD1_k127_7184878_13 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000009445 260.0
HKD1_k127_7184878_14 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000002387 259.0
HKD1_k127_7184878_15 Thioesterase superfamily K18014 - 4.3.1.14 0.00000000000000000000000000000000000000000299 166.0
HKD1_k127_7184878_16 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000007779 152.0
HKD1_k127_7184878_17 YXWGXW repeat (2 copies) - - - 0.0000000000000000000005793 100.0
HKD1_k127_7184878_18 - - - - 0.000000000003053 80.0
HKD1_k127_7184878_2 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 492.0
HKD1_k127_7184878_20 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K16079 - - 0.0002077 53.0
HKD1_k127_7184878_3 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 392.0
HKD1_k127_7184878_4 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 362.0
HKD1_k127_7184878_5 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 352.0
HKD1_k127_7184878_6 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 341.0
HKD1_k127_7184878_7 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 340.0
HKD1_k127_7184878_8 amino acid K03294,K13868 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 346.0
HKD1_k127_7184878_9 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 321.0
HKD1_k127_7219987_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1273.0
HKD1_k127_7219987_1 Belongs to the peptidase M16 family K07263 - - 0.0 1138.0
HKD1_k127_7219987_10 tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008797 479.0
HKD1_k127_7219987_11 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 459.0
HKD1_k127_7219987_12 Amino acid permease K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 338.0
HKD1_k127_7219987_13 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 328.0
HKD1_k127_7219987_14 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 343.0
HKD1_k127_7219987_15 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 315.0
HKD1_k127_7219987_16 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006473 286.0
HKD1_k127_7219987_17 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000003809 188.0
HKD1_k127_7219987_18 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000002015 146.0
HKD1_k127_7219987_19 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000003217 133.0
HKD1_k127_7219987_2 cellulose binding - - - 3.225e-272 871.0
HKD1_k127_7219987_20 signal transduction histidine kinase K07642 - 2.7.13.3 0.00000000000000000000000008731 121.0
HKD1_k127_7219987_21 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000000000000000000000001314 115.0
HKD1_k127_7219987_22 Chromate resistance exported protein - - - 0.0000000000000000000002275 102.0
HKD1_k127_7219987_23 PFAM response regulator receiver K07657,K07658 - - 0.00000000000000000003096 106.0
HKD1_k127_7219987_24 Transcriptional regulator - - - 0.00000000000000002591 88.0
HKD1_k127_7219987_25 YsiA-like protein, C-terminal region K13770 - - 0.00000000000000003463 89.0
HKD1_k127_7219987_26 PFAM iron dependent repressor K03709 - - 0.0000000001921 69.0
HKD1_k127_7219987_27 WHG domain - - - 0.00000007001 59.0
HKD1_k127_7219987_29 FeoA K04758 - - 0.0001871 54.0
HKD1_k127_7219987_3 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 2.856e-237 795.0
HKD1_k127_7219987_30 - - - - 0.0004335 46.0
HKD1_k127_7219987_4 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 3.781e-204 656.0
HKD1_k127_7219987_5 Involved in the tonB-independent uptake of proteins - - - 4.355e-202 673.0
HKD1_k127_7219987_6 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 646.0
HKD1_k127_7219987_7 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 574.0
HKD1_k127_7219987_8 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 541.0
HKD1_k127_7219987_9 Cobalamin-independent synthase, Catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 492.0
HKD1_k127_7225163_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 302.0
HKD1_k127_7225163_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000001354 175.0
HKD1_k127_7249232_0 AcrB/AcrD/AcrF family - - - 0.0 1103.0
HKD1_k127_7249232_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.653e-255 826.0
HKD1_k127_7249232_10 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 334.0
HKD1_k127_7249232_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 297.0
HKD1_k127_7249232_12 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 299.0
HKD1_k127_7249232_13 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009937 262.0
HKD1_k127_7249232_14 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000006749 285.0
HKD1_k127_7249232_15 Glycosyltransferase family 28 N-terminal domain K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000006697 259.0
HKD1_k127_7249232_16 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000001142 205.0
HKD1_k127_7249232_17 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000004575 144.0
HKD1_k127_7249232_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000108 118.0
HKD1_k127_7249232_19 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.00000000000000000000003431 118.0
HKD1_k127_7249232_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 540.0
HKD1_k127_7249232_20 Sulfurtransferase - - - 0.0000000000000006914 93.0
HKD1_k127_7249232_21 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0000001142 59.0
HKD1_k127_7249232_22 Outer membrane efflux protein - - - 0.0000003284 63.0
HKD1_k127_7249232_23 Cell division protein FtsQ K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.0000007692 59.0
HKD1_k127_7249232_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 480.0
HKD1_k127_7249232_4 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 494.0
HKD1_k127_7249232_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 439.0
HKD1_k127_7249232_6 PASTA domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 436.0
HKD1_k127_7249232_7 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 416.0
HKD1_k127_7249232_8 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008115 417.0
HKD1_k127_7249232_9 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 377.0
HKD1_k127_7250665_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1354.0
HKD1_k127_7250665_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 340.0
HKD1_k127_7250665_10 Putative adhesin - - - 0.000000000005652 77.0
HKD1_k127_7250665_11 FAD dependent oxidoreductase - - - 0.0000000002588 62.0
HKD1_k127_7250665_12 peptidyl-tyrosine sulfation - - - 0.0000000484 66.0
HKD1_k127_7250665_13 Protein tyrosine kinase K12132 - 2.7.11.1 0.000003059 61.0
HKD1_k127_7250665_2 Associated with various cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 358.0
HKD1_k127_7250665_3 metallochaperone-like domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003371 278.0
HKD1_k127_7250665_4 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000006237 246.0
HKD1_k127_7250665_5 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000002327 248.0
HKD1_k127_7250665_6 XdhC Rossmann domain - - - 0.000000000000000000000000000000000000000000000000000000006869 212.0
HKD1_k127_7250665_7 MobA-Related Protein K07141 - 2.7.7.76 0.000000000000000000000000000000000000000005467 165.0
HKD1_k127_7250665_8 - - - - 0.00000000000000000000000000000000000000005314 174.0
HKD1_k127_7250665_9 Penicillinase repressor - - - 0.000000000000000000000000000000000000001005 151.0
HKD1_k127_7278442_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.928e-289 898.0
HKD1_k127_7278442_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 8.401e-225 703.0
HKD1_k127_7278442_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 381.0
HKD1_k127_7278442_3 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001749 284.0
HKD1_k127_7279824_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 592.0
HKD1_k127_7279824_1 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 486.0
HKD1_k127_7279824_10 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000002403 218.0
HKD1_k127_7279824_11 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000004508 205.0
HKD1_k127_7279824_12 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000004851 210.0
HKD1_k127_7279824_13 Sulfate ABC transporter periplasmic sulfate-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000002268 195.0
HKD1_k127_7279824_14 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000004982 183.0
HKD1_k127_7279824_15 ATPase-coupled sulfate transmembrane transporter activity K02046,K02047 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000003805 198.0
HKD1_k127_7279824_16 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000006211 150.0
HKD1_k127_7279824_17 TRANSCRIPTIONal - - - 0.0000000000000000000000000000000006824 132.0
HKD1_k127_7279824_18 transglycosylase K08309 - - 0.00000000000000000000000000000004045 145.0
HKD1_k127_7279824_19 YCII-related domain - - - 0.0000000000000000000000009309 108.0
HKD1_k127_7279824_2 membrane protein, terc K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000788 473.0
HKD1_k127_7279824_20 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000009307 102.0
HKD1_k127_7279824_21 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000001193 116.0
HKD1_k127_7279824_22 nuclear chromosome segregation - - - 0.0000000000000000000007883 110.0
HKD1_k127_7279824_23 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000006234 90.0
HKD1_k127_7279824_24 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000001503 98.0
HKD1_k127_7279824_26 Acetyltransferase (GNAT) domain - - - 0.000009893 50.0
HKD1_k127_7279824_3 ATPase activity K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 454.0
HKD1_k127_7279824_4 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 362.0
HKD1_k127_7279824_5 ATPase domain of DNA mismatch repair MUTS family K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 376.0
HKD1_k127_7279824_6 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005215 271.0
HKD1_k127_7279824_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000615 243.0
HKD1_k127_7279824_8 iron ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000008305 227.0
HKD1_k127_7279824_9 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000002543 220.0
HKD1_k127_728087_0 B12 binding domain - - - 8.473e-226 709.0
HKD1_k127_728087_1 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 503.0
HKD1_k127_728087_2 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000324 260.0
HKD1_k127_728087_3 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001993 216.0
HKD1_k127_728087_4 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000001261 194.0
HKD1_k127_728087_5 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000001614 154.0
HKD1_k127_728087_6 Bacterial lipid A biosynthesis acyltransferase - - - 0.000000000000000000000000004404 126.0
HKD1_k127_7285402_0 DEAD DEAH box helicase K03724 - - 0.0 1331.0
HKD1_k127_7285402_1 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K00256 - 1.3.99.16 8.773e-289 911.0
HKD1_k127_7285402_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000004793 93.0
HKD1_k127_7285402_12 Beta-lactamase - - - 0.00000000001193 78.0
HKD1_k127_7285402_13 - - - - 0.00001166 57.0
HKD1_k127_7285402_14 COG3794 Plastocyanin - - - 0.00001278 56.0
HKD1_k127_7285402_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 532.0
HKD1_k127_7285402_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 415.0
HKD1_k127_7285402_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001773 299.0
HKD1_k127_7285402_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008027 269.0
HKD1_k127_7285402_6 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000009113 226.0
HKD1_k127_7285402_7 2Fe-2S -binding domain protein K18029 - 1.17.2.1 0.00000000000000000000000000000000000000000000000000000002194 203.0
HKD1_k127_7285402_8 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000005245 162.0
HKD1_k127_7285402_9 Thioredoxin-like - - - 0.00000000000000000000000003183 115.0
HKD1_k127_7356308_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 600.0
HKD1_k127_7356308_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 430.0
HKD1_k127_7356308_10 Putative single-stranded nucleic acids-binding domain K06346 - - 0.00000000000000000208 94.0
HKD1_k127_7356308_11 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000006908 72.0
HKD1_k127_7356308_12 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000874 62.0
HKD1_k127_7356308_2 NUBPL iron-transfer P-loop NTPase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 315.0
HKD1_k127_7356308_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005967 267.0
HKD1_k127_7356308_4 PFAM ParB domain protein nuclease K03497 - - 0.000000000000000000000000000000000000000000000000000000000001341 227.0
HKD1_k127_7356308_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000001173 205.0
HKD1_k127_7356308_6 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000002791 107.0
HKD1_k127_7356308_7 Polymer-forming cytoskeletal - - - 0.0000000000000000000002366 102.0
HKD1_k127_7356308_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000001365 103.0
HKD1_k127_7356308_9 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000001677 87.0
HKD1_k127_7370013_0 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.782e-201 646.0
HKD1_k127_7370013_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 506.0
HKD1_k127_7370013_10 - - - - 0.000000001134 65.0
HKD1_k127_7370013_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 490.0
HKD1_k127_7370013_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 326.0
HKD1_k127_7370013_4 quinone binding K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 329.0
HKD1_k127_7370013_5 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000005577 171.0
HKD1_k127_7370013_6 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000000000371 168.0
HKD1_k127_7370013_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000003416 106.0
HKD1_k127_7370013_8 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000002335 100.0
HKD1_k127_7370013_9 - - - - 0.00000000000009899 80.0
HKD1_k127_7374432_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 615.0
HKD1_k127_7374432_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 349.0
HKD1_k127_7374432_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000106 140.0
HKD1_k127_7374432_11 Belongs to the UPF0312 family - - - 0.000000000000000000000004937 120.0
HKD1_k127_7374432_2 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 365.0
HKD1_k127_7374432_3 Peptidase family M1 domain K01256,K08776 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 361.0
HKD1_k127_7374432_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 329.0
HKD1_k127_7374432_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002248 280.0
HKD1_k127_7374432_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002901 291.0
HKD1_k127_7374432_7 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001955 261.0
HKD1_k127_7374432_8 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000003679 206.0
HKD1_k127_7374432_9 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000001384 156.0
HKD1_k127_7384394_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 296.0
HKD1_k127_7384394_1 DinB superfamily - - - 0.000000000000000000000000000000000004632 140.0
HKD1_k127_7384394_2 - K01992,K19341 - - 0.000000000000000000000000000000297 141.0
HKD1_k127_7447181_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 345.0
HKD1_k127_7447181_1 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000000001822 206.0
HKD1_k127_7447181_2 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000001136 194.0
HKD1_k127_7447181_3 Domain of Unknown Function (DUF1206) - - - 0.000000000000000000000002759 116.0
HKD1_k127_7455477_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000001388 124.0
HKD1_k127_7455477_1 - - - - 0.00000004287 59.0
HKD1_k127_7477175_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 575.0
HKD1_k127_7477175_1 protein secretion by the type I secretion system K11085 - - 0.00000000000000000000000000000000000000000000000000000000000003282 222.0
HKD1_k127_7477175_2 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000001062 192.0
HKD1_k127_7477175_3 -acetyltransferase - - - 0.000000000000000000000000000000000000000000000002889 177.0
HKD1_k127_7477175_4 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000006934 168.0
HKD1_k127_7477175_5 Helix-turn-helix domain - - - 0.000000000000000000000000000000009914 135.0
HKD1_k127_7503012_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.099e-286 905.0
HKD1_k127_7503012_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.564e-272 867.0
HKD1_k127_7503012_10 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 391.0
HKD1_k127_7503012_11 ATP-dependent helicase activity K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 400.0
HKD1_k127_7503012_12 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 402.0
HKD1_k127_7503012_13 Aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 377.0
HKD1_k127_7503012_14 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 353.0
HKD1_k127_7503012_15 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 353.0
HKD1_k127_7503012_16 Pfam:Arch_ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001671 286.0
HKD1_k127_7503012_17 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001788 289.0
HKD1_k127_7503012_18 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006618 292.0
HKD1_k127_7503012_19 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000001077 278.0
HKD1_k127_7503012_2 peptidase K07386 - - 1.541e-263 830.0
HKD1_k127_7503012_20 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000001534 267.0
HKD1_k127_7503012_21 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000002319 258.0
HKD1_k127_7503012_22 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000001135 255.0
HKD1_k127_7503012_23 Enoyl-CoA hydratase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000007841 252.0
HKD1_k127_7503012_24 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000522 229.0
HKD1_k127_7503012_25 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000002964 248.0
HKD1_k127_7503012_26 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000002173 238.0
HKD1_k127_7503012_27 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000002924 226.0
HKD1_k127_7503012_28 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000003199 231.0
HKD1_k127_7503012_29 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000003458 214.0
HKD1_k127_7503012_3 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 2.529e-250 784.0
HKD1_k127_7503012_30 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000002181 205.0
HKD1_k127_7503012_31 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000002802 220.0
HKD1_k127_7503012_32 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000003712 217.0
HKD1_k127_7503012_33 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000009595 214.0
HKD1_k127_7503012_34 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000005336 187.0
HKD1_k127_7503012_35 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000001392 168.0
HKD1_k127_7503012_36 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.000000000000000000000000000000000000000001083 162.0
HKD1_k127_7503012_37 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000455 167.0
HKD1_k127_7503012_38 3-dehydroquinate dehydratase activity K00014,K03785,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000001851 171.0
HKD1_k127_7503012_39 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000001085 162.0
HKD1_k127_7503012_4 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 4.424e-211 666.0
HKD1_k127_7503012_40 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000007764 165.0
HKD1_k127_7503012_41 DNA mismatch repair protein MutT K01515 - 3.6.1.13 0.00000000000000000000000000000000000001641 150.0
HKD1_k127_7503012_42 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.00000000000000000000000000000000000006154 162.0
HKD1_k127_7503012_43 Crp-like helix-turn-helix domain K10914 - - 0.00000000000000000000000000000000004321 154.0
HKD1_k127_7503012_44 DinB superfamily - - - 0.000000000000000000000000000000001144 141.0
HKD1_k127_7503012_45 cheY-homologous receiver domain - - - 0.00000000000000000000000000000002096 142.0
HKD1_k127_7503012_46 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000001403 141.0
HKD1_k127_7503012_47 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000319 128.0
HKD1_k127_7503012_48 domain, Protein - - - 0.0000000000000000000000000000832 134.0
HKD1_k127_7503012_49 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.0000000000000000000000000001936 132.0
HKD1_k127_7503012_5 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 519.0
HKD1_k127_7503012_50 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000008051 128.0
HKD1_k127_7503012_51 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000002545 126.0
HKD1_k127_7503012_52 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000005358 109.0
HKD1_k127_7503012_53 Helix-turn-helix domain - - - 0.000000000000000000006667 103.0
HKD1_k127_7503012_54 - - - - 0.00000000000000000000681 108.0
HKD1_k127_7503012_55 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000001831 102.0
HKD1_k127_7503012_56 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 0.00000000000000003295 93.0
HKD1_k127_7503012_57 - - - - 0.000000000000001595 85.0
HKD1_k127_7503012_58 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000001671 80.0
HKD1_k127_7503012_59 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000009817 73.0
HKD1_k127_7503012_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 497.0
HKD1_k127_7503012_60 Polymer-forming cytoskeletal - - - 0.00000000003087 70.0
HKD1_k127_7503012_61 Glutaredoxin-like domain (DUF836) - - - 0.0000001035 63.0
HKD1_k127_7503012_62 Putative adhesin - - - 0.00002976 57.0
HKD1_k127_7503012_63 desiccation-related protein LEA14 - GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006952,GO:0008150,GO:0009314,GO:0009416,GO:0009605,GO:0009607,GO:0009611,GO:0009620,GO:0009628,GO:0009642,GO:0009644,GO:0016020,GO:0043207,GO:0044424,GO:0044444,GO:0044464,GO:0048046,GO:0050832,GO:0050896,GO:0051704,GO:0051707,GO:0071944,GO:0098542 - 0.0002965 53.0
HKD1_k127_7503012_7 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 482.0
HKD1_k127_7503012_8 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 469.0
HKD1_k127_7503012_9 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 462.0
HKD1_k127_7535178_0 Carboxypeptidase regulatory-like domain - - - 4.847e-204 670.0
HKD1_k127_7535178_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 534.0
HKD1_k127_7535178_10 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000315 273.0
HKD1_k127_7535178_11 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006208 274.0
HKD1_k127_7535178_12 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005297 275.0
HKD1_k127_7535178_13 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000063 280.0
HKD1_k127_7535178_14 A G-specific K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000105 251.0
HKD1_k127_7535178_15 Phenylacetate-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000006651 220.0
HKD1_k127_7535178_16 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000001815 203.0
HKD1_k127_7535178_17 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.0000000000000000000000000000000000000000000000000000007895 220.0
HKD1_k127_7535178_18 - - - - 0.000000000000000000000000000000000000000000000004736 180.0
HKD1_k127_7535178_19 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000004724 170.0
HKD1_k127_7535178_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 501.0
HKD1_k127_7535178_20 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000009791 172.0
HKD1_k127_7535178_21 oxidoreductase activity K12511 - - 0.000000000000000000000000000000000000005325 158.0
HKD1_k127_7535178_22 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000005391 153.0
HKD1_k127_7535178_23 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000001125 134.0
HKD1_k127_7535178_24 Peptidase family M23 K21471 - - 0.0000000000000000000000001373 125.0
HKD1_k127_7535178_25 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.0000000000000000000000007107 113.0
HKD1_k127_7535178_26 Radical SAM superfamily - - - 0.00000000000000000000000471 115.0
HKD1_k127_7535178_27 Bacterial membrane protein YfhO - - - 0.000000000000000009591 98.0
HKD1_k127_7535178_28 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000005446 90.0
HKD1_k127_7535178_29 Uncharacterised protein family (UPF0158) - - - 0.000000297 59.0
HKD1_k127_7535178_3 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 478.0
HKD1_k127_7535178_30 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0002596 52.0
HKD1_k127_7535178_31 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0006199 53.0
HKD1_k127_7535178_4 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 456.0
HKD1_k127_7535178_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 428.0
HKD1_k127_7535178_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 394.0
HKD1_k127_7535178_7 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 389.0
HKD1_k127_7535178_8 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 366.0
HKD1_k127_7535178_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 327.0
HKD1_k127_7563965_0 Sulfate permease family - - - 3.691e-228 723.0
HKD1_k127_7563965_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 566.0
HKD1_k127_7563965_2 COG NOG10142 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 445.0
HKD1_k127_7563965_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 431.0
HKD1_k127_7563965_4 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 400.0
HKD1_k127_7563965_5 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D K01424,K05597 GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0032787,GO:0034641,GO:0042597,GO:0042802,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1,3.5.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 371.0
HKD1_k127_7596226_0 AI-2E family transporter - - - 0.00000000000000000000000000000000002374 151.0
HKD1_k127_7596226_1 chlorophyll binding - - - 0.00000000000000003072 94.0
HKD1_k127_7596226_2 Cytochrome c554 and c-prime - - - 0.00000000000001533 76.0
HKD1_k127_7605540_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 405.0
HKD1_k127_7605540_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000005879 202.0
HKD1_k127_7608978_0 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 556.0
HKD1_k127_7608978_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000005319 224.0
HKD1_k127_7608978_2 Methyltransferase domain - - - 0.0000000000000000000001497 106.0
HKD1_k127_7628071_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1289.0
HKD1_k127_7628071_1 Cation transporter/ATPase, N-terminus - - - 1.904e-239 765.0
HKD1_k127_7628071_10 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001745 291.0
HKD1_k127_7628071_11 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000001622 261.0
HKD1_k127_7628071_12 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000003635 242.0
HKD1_k127_7628071_13 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000001067 226.0
HKD1_k127_7628071_14 POT family K03305 - - 0.000000000000000000000000000000000000000000000000009574 189.0
HKD1_k127_7628071_15 Cytochrome c - - - 0.0000000000000000000000000000009829 131.0
HKD1_k127_7628071_16 cytochrome C assembly protein - - - 0.00000000000002886 84.0
HKD1_k127_7628071_17 Uroporphyrinogen-III synthase HemD K01719,K13542 - 2.1.1.107,4.2.1.75 0.0000001238 64.0
HKD1_k127_7628071_18 Universal stress protein - - - 0.000005196 57.0
HKD1_k127_7628071_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 463.0
HKD1_k127_7628071_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000747 486.0
HKD1_k127_7628071_4 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 429.0
HKD1_k127_7628071_5 Involved in the biosynthesis of porphyrin-containing compound K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 446.0
HKD1_k127_7628071_6 PFAM Leukotriene A4 hydrolase, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 408.0
HKD1_k127_7628071_7 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 419.0
HKD1_k127_7628071_8 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 304.0
HKD1_k127_7628071_9 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 319.0
HKD1_k127_7661066_0 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 549.0
HKD1_k127_7661066_1 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 520.0
HKD1_k127_7661066_10 Gaf domain K07814 - - 0.0000000000000000000000000000000000001194 156.0
HKD1_k127_7661066_11 phosphate ion binding - - - 0.0000000000000000000000002508 124.0
HKD1_k127_7661066_12 phosphorelay signal transduction system K19622 - - 0.000000000000000000001903 99.0
HKD1_k127_7661066_13 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000002385 64.0
HKD1_k127_7661066_2 Four helix bundle sensory module for signal transduction K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 381.0
HKD1_k127_7661066_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 381.0
HKD1_k127_7661066_4 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 339.0
HKD1_k127_7661066_5 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 324.0
HKD1_k127_7661066_6 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000001484 185.0
HKD1_k127_7661066_7 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000007323 183.0
HKD1_k127_7661066_8 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000000000000000000000009443 164.0
HKD1_k127_7661066_9 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 3.5.1.44 0.0000000000000000000000000000000000000003725 165.0
HKD1_k127_7868852_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000003794 199.0
HKD1_k127_7868852_1 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000000000214 170.0
HKD1_k127_7868852_2 Metallo-peptidase family M12 - - - 0.000000000000000002682 101.0
HKD1_k127_7868852_3 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.000002418 62.0
HKD1_k127_7927867_0 PFAM Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004612 246.0
HKD1_k127_7927867_1 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000001878 228.0
HKD1_k127_7927867_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000006068 134.0
HKD1_k127_7927867_3 Dolichyl-phosphate-mannose-protein mannosyltransferase K14340 - - 0.0000000001356 75.0
HKD1_k127_7939736_0 Aminotransferase class-III - - - 2.202e-209 662.0
HKD1_k127_7939736_1 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 356.0
HKD1_k127_7939736_2 peptidase K07386 - - 0.00001096 50.0
HKD1_k127_8003123_0 ABC transporter transmembrane region K06147,K18893 - - 4.095e-252 792.0
HKD1_k127_8003123_1 oligopeptide transporter, OPT family - - - 2.065e-214 685.0
HKD1_k127_8003123_10 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000004169 214.0
HKD1_k127_8003123_11 PFAM Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000005474 204.0
HKD1_k127_8003123_12 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000001565 180.0
HKD1_k127_8003123_13 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000001479 160.0
HKD1_k127_8003123_14 Protein tyrosine kinase - - - 0.000000000000000000000000000007747 136.0
HKD1_k127_8003123_15 - - - - 0.000000000000000000000000001945 129.0
HKD1_k127_8003123_16 CopG domain protein DNA-binding domain protein K18918 - - 0.000000000000001808 78.0
HKD1_k127_8003123_17 TIGRFAM addiction module toxin, RelE StbE family K06218 - - 0.00000000001174 71.0
HKD1_k127_8003123_18 Putative porin - - - 0.00000000004497 74.0
HKD1_k127_8003123_19 Response regulator, receiver - - - 0.0000000002456 66.0
HKD1_k127_8003123_2 Phospholipase D. Active site motifs. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 465.0
HKD1_k127_8003123_20 Domain of unknown function (DUF4139) - - - 0.0001766 54.0
HKD1_k127_8003123_3 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 424.0
HKD1_k127_8003123_4 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 407.0
HKD1_k127_8003123_5 Acetamidase/Formamidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 392.0
HKD1_k127_8003123_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 316.0
HKD1_k127_8003123_7 Imidazolonepropionase and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 309.0
HKD1_k127_8003123_8 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 316.0
HKD1_k127_8003123_9 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000000000000000009646 244.0
HKD1_k127_833036_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 505.0
HKD1_k127_833036_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 480.0
HKD1_k127_833036_10 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000002801 68.0
HKD1_k127_833036_11 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.000001232 50.0
HKD1_k127_833036_12 Fungalysin metallopeptidase (M36) - - - 0.00005243 57.0
HKD1_k127_833036_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 478.0
HKD1_k127_833036_3 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 467.0
HKD1_k127_833036_4 PFAM Na-Ca exchanger integrin-beta4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 420.0
HKD1_k127_833036_5 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 302.0
HKD1_k127_833036_6 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000001694 179.0
HKD1_k127_833036_7 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000002016 176.0
HKD1_k127_833036_8 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000733 169.0
HKD1_k127_833036_9 HemY domain protein - - - 0.00000000000000000000000000000000000002141 169.0
HKD1_k127_90498_0 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001983 246.0
HKD1_k127_90498_1 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000007688 169.0
HKD1_k127_90498_2 - - - - 0.000000000000000000000000000000000004357 148.0
HKD1_k127_90498_3 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000004954 115.0
HKD1_k127_90498_4 - - - - 0.0000000000000001374 91.0
HKD1_k127_90498_5 - - - - 0.000000000000008331 89.0