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Overview

ID MAG01708
Name HKD1_bin.20
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota_B
Class Binatia
Order HRBIN30
Family CADEER01
Genus JAHBUY01
Species
Assembly information
Completeness (%) 82.08
Contamination (%) 0.19
GC content (%) 71.0
N50 (bp) 7,431
Genome size (bp) 3,765,031

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3209

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1003928_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 469.0
HKD1_k127_1003928_1 Cell division protein ftsk K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 422.0
HKD1_k127_1003928_2 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 419.0
HKD1_k127_1003928_3 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007865 250.0
HKD1_k127_1003928_4 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000002968 197.0
HKD1_k127_1003928_5 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000006526 196.0
HKD1_k127_1003928_6 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000000008859 150.0
HKD1_k127_1003928_7 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000001839 125.0
HKD1_k127_1003928_8 - - - - 0.0000000000000000000004098 103.0
HKD1_k127_1015049_0 PFAM ABC transporter related K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 563.0
HKD1_k127_1015049_1 YceG-like family K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000248 269.0
HKD1_k127_1015049_2 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000007677 248.0
HKD1_k127_1015049_3 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000008362 216.0
HKD1_k127_1015049_4 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000001674 209.0
HKD1_k127_1015049_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000001166 162.0
HKD1_k127_1015049_6 General secretion pathway protein C K02452 - - 0.0000000000000000000000000000000000006018 151.0
HKD1_k127_1015049_7 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000009496 134.0
HKD1_k127_1015049_8 Glycosyl transferase family 21 K00720 GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006677,GO:0006678,GO:0006679,GO:0006687,GO:0006688,GO:0006807,GO:0008120,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0009058,GO:0009247,GO:0009405,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030148,GO:0030447,GO:0034641,GO:0035251,GO:0040007,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044419,GO:0046467,GO:0046476,GO:0046513,GO:0046527,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.4.1.80 0.0003617 44.0
HKD1_k127_1018551_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 4.621e-281 887.0
HKD1_k127_1018551_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 6.294e-222 719.0
HKD1_k127_1018551_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000005535 215.0
HKD1_k127_1040138_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 9.117e-238 750.0
HKD1_k127_1040138_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 629.0
HKD1_k127_1040138_2 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000004907 153.0
HKD1_k127_1042426_0 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000005725 245.0
HKD1_k127_1042426_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000004982 220.0
HKD1_k127_1042426_2 dehydratase - - - 0.000000000000000001063 96.0
HKD1_k127_1042426_3 - - - - 0.0000000006228 70.0
HKD1_k127_1042426_4 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.0004181 48.0
HKD1_k127_1059621_0 TrkA-C domain K03455 - - 1.084e-227 724.0
HKD1_k127_1059621_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 409.0
HKD1_k127_1059621_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 337.0
HKD1_k127_1059621_3 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001247 265.0
HKD1_k127_1059621_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000002482 196.0
HKD1_k127_1059621_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000001177 206.0
HKD1_k127_1059621_6 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000002709 87.0
HKD1_k127_1059621_7 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000006619 72.0
HKD1_k127_1063081_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 597.0
HKD1_k127_1063081_1 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 413.0
HKD1_k127_1063081_2 COG0625 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 413.0
HKD1_k127_1063081_3 Histidine kinase K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000003379 202.0
HKD1_k127_1063081_4 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000004298 177.0
HKD1_k127_1063081_5 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.000000000000000000000000000000000003672 146.0
HKD1_k127_1063081_6 COG1309 Transcriptional regulator - - - 0.0000000000000000000000000000000001682 140.0
HKD1_k127_1063081_7 NAD(P)+ transhydrogenase (AB-specific) activity K00324 - 1.6.1.2 0.00000000000000000000000004333 120.0
HKD1_k127_1086043_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.652e-292 916.0
HKD1_k127_1086043_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 375.0
HKD1_k127_1086043_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 341.0
HKD1_k127_1086043_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043918,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000006673 168.0
HKD1_k127_1086043_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000003488 87.0
HKD1_k127_1089283_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 569.0
HKD1_k127_1089283_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 319.0
HKD1_k127_1089283_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 293.0
HKD1_k127_1089283_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000004631 203.0
HKD1_k127_1089283_4 YbbR-like protein - - - 0.0000000000000000000000002622 121.0
HKD1_k127_1089843_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 435.0
HKD1_k127_1089843_1 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 305.0
HKD1_k127_1089843_2 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009157 269.0
HKD1_k127_1089843_3 membrane protein domain - - - 0.00000072 59.0
HKD1_k127_1093606_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 419.0
HKD1_k127_1093606_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 332.0
HKD1_k127_1093606_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000007944 180.0
HKD1_k127_1093606_3 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000001191 107.0
HKD1_k127_1093606_4 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000009778 94.0
HKD1_k127_1093606_5 Colicin V production protein K03558 - - 0.0000006786 58.0
HKD1_k127_1101581_0 TIGRFAM phosphoenolpyruvate-protein phosphotransferase K08484 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 466.0
HKD1_k127_1101581_1 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000003005 154.0
HKD1_k127_1101581_2 MMPL family K07003 - - 0.0000000000000000000000002 113.0
HKD1_k127_1112387_0 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 1.913e-258 831.0
HKD1_k127_1112387_1 Fatty acid cis/trans isomerase (CTI) - - - 4.501e-206 670.0
HKD1_k127_1112387_2 Belongs to the long-chain O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001676 230.0
HKD1_k127_1112387_3 - - - - 0.000000000000000000000000000000002619 130.0
HKD1_k127_1112387_4 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000001863 103.0
HKD1_k127_1127017_0 Belongs to the amidase family K01426 - 3.5.1.4 3.941e-214 674.0
HKD1_k127_1127017_1 Domain of unknown function (DUF4040) K05559,K05565 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 493.0
HKD1_k127_1127017_2 nucleoside metabolic process - - - 0.00000000000000000000000000000000000003278 154.0
HKD1_k127_1138980_0 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004708 284.0
HKD1_k127_1138980_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001404 237.0
HKD1_k127_1138980_2 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000002522 228.0
HKD1_k127_1138980_3 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000279 145.0
HKD1_k127_1138980_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000002126 70.0
HKD1_k127_1138980_5 TPR repeat - - - 0.0004828 44.0
HKD1_k127_1148477_0 PFAM Di-heme cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 574.0
HKD1_k127_1148477_1 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 577.0
HKD1_k127_1148477_2 Cytochrome c K19713 - 1.8.2.2 0.00000000000000000000000000000000000000000000000000000000008102 229.0
HKD1_k127_1148477_3 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000007257 83.0
HKD1_k127_1148477_4 belongs to the Fur family K03711,K09825 - - 0.00000000000000657 81.0
HKD1_k127_1166494_0 (ABC) transporter K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 490.0
HKD1_k127_1166494_1 ABC transporter K06148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 479.0
HKD1_k127_1166494_10 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000006355 198.0
HKD1_k127_1166494_11 MobA-like NTP transferase domain - - - 0.000000000000000000000000000000000000000000002096 186.0
HKD1_k127_1166494_12 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000003665 160.0
HKD1_k127_1166494_13 Histidine kinase-like ATPases - - - 0.000000004619 57.0
HKD1_k127_1166494_2 acetyltransferase - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 439.0
HKD1_k127_1166494_3 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 361.0
HKD1_k127_1166494_4 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 342.0
HKD1_k127_1166494_5 Aspartyl Asparaginyl beta-hydroxylase K12979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002423 266.0
HKD1_k127_1166494_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001562 264.0
HKD1_k127_1166494_7 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000004232 198.0
HKD1_k127_1166494_8 KR domain - - - 0.00000000000000000000000000000000000000000000000000001789 199.0
HKD1_k127_1166494_9 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000002553 194.0
HKD1_k127_1175175_0 Flavin-binding monooxygenase-like K14520 - 1.14.13.84 3.598e-250 789.0
HKD1_k127_1175175_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00249 - 1.3.8.7 1.21e-210 660.0
HKD1_k127_1175175_2 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 416.0
HKD1_k127_1175175_3 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 359.0
HKD1_k127_1175175_4 transporter K03292 - - 0.00000000000000000000000000000000000005015 159.0
HKD1_k127_1175175_5 - - - - 0.00000000000000000000000000000000000006337 163.0
HKD1_k127_1175175_6 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000004411 106.0
HKD1_k127_120173_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.614e-272 859.0
HKD1_k127_120173_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 4.692e-260 822.0
HKD1_k127_120173_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000646 192.0
HKD1_k127_120173_11 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000003922 169.0
HKD1_k127_120173_12 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000009 164.0
HKD1_k127_120173_13 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000001301 166.0
HKD1_k127_120173_14 Ribosomal protein L9, N-terminal domain K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000008668 155.0
HKD1_k127_120173_15 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000002133 142.0
HKD1_k127_120173_16 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000006711 132.0
HKD1_k127_120173_17 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000006924 133.0
HKD1_k127_120173_18 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000006647 125.0
HKD1_k127_120173_19 protein-(glutamine-N5) methyltransferase activity - - - 0.0000000000000000000000000002615 131.0
HKD1_k127_120173_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.299e-254 812.0
HKD1_k127_120173_20 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000006154 107.0
HKD1_k127_120173_21 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000001302 111.0
HKD1_k127_120173_22 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01923,K01952 - 6.3.2.6,6.3.5.3 0.000000000000000000000002609 105.0
HKD1_k127_120173_23 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000003748 104.0
HKD1_k127_120173_24 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000004756 119.0
HKD1_k127_120173_25 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000001935 93.0
HKD1_k127_120173_26 - - - - 0.00000000000000000005114 91.0
HKD1_k127_120173_27 Predicted membrane protein (DUF2232) - - - 0.0000000000000000002314 100.0
HKD1_k127_120173_28 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000002261 89.0
HKD1_k127_120173_29 PFAM PQQ enzyme repeat - - - 0.000000000000002593 89.0
HKD1_k127_120173_3 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 608.0
HKD1_k127_120173_30 Protein of unknown function (DUF448) K07742 - - 0.00000008592 59.0
HKD1_k127_120173_4 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 455.0
HKD1_k127_120173_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 417.0
HKD1_k127_120173_6 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 387.0
HKD1_k127_120173_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002725 285.0
HKD1_k127_120173_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000008968 241.0
HKD1_k127_120173_9 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000001815 189.0
HKD1_k127_1216145_0 aldo-keto reductase (NADP) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 292.0
HKD1_k127_1216145_1 domain protein K13735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006408 298.0
HKD1_k127_1216145_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000002126 125.0
HKD1_k127_1216145_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000008874 66.0
HKD1_k127_1216145_4 Belongs to the peptidase S8 family - - - 0.0000008793 62.0
HKD1_k127_1216145_5 - - - - 0.0001128 53.0
HKD1_k127_1221128_0 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 387.0
HKD1_k127_1221627_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 461.0
HKD1_k127_1221627_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000004706 227.0
HKD1_k127_1221627_2 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000009576 153.0
HKD1_k127_1221627_4 4Fe-4S single cluster domain - - - 0.000002613 56.0
HKD1_k127_1225283_0 PFAM Radical SAM - - - 1.089e-200 642.0
HKD1_k127_1225283_1 KR domain - - - 0.0000000000000000000002363 101.0
HKD1_k127_1267195_0 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 538.0
HKD1_k127_1267195_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 330.0
HKD1_k127_1267195_2 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003342 285.0
HKD1_k127_1267195_3 cytochrome C peroxidase - - - 0.00000000000000000003424 105.0
HKD1_k127_1270395_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 574.0
HKD1_k127_1270395_1 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 415.0
HKD1_k127_1270395_2 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003098 282.0
HKD1_k127_1270395_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000008423 249.0
HKD1_k127_1270395_4 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000005781 209.0
HKD1_k127_1270395_5 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000002884 194.0
HKD1_k127_1270395_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000417 199.0
HKD1_k127_1270395_7 response regulator receiver K13041 - - 0.00000000000000000000000000000000000000002892 163.0
HKD1_k127_1272639_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 512.0
HKD1_k127_1272639_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 381.0
HKD1_k127_1272639_2 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 323.0
HKD1_k127_1272639_3 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000006125 209.0
HKD1_k127_1272639_4 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000006742 179.0
HKD1_k127_1272639_5 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K00652,K01935 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47,6.3.3.3 0.00000000000000000000000000000000000000000000006466 177.0
HKD1_k127_1272639_6 - K07018 - - 0.0000000000000000000000000000000000003455 148.0
HKD1_k127_1272639_7 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000002707 123.0
HKD1_k127_1272639_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000001056 106.0
HKD1_k127_1272639_9 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000009002 79.0
HKD1_k127_1280806_0 TIGRFAM TraB family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 403.0
HKD1_k127_1280806_1 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 396.0
HKD1_k127_1280806_2 - - - - 0.0000000000000000000000000000000000000000000002577 178.0
HKD1_k127_1280806_3 histidine kinase A domain protein - - - 0.00000000000000000000000000000000001088 155.0
HKD1_k127_1280806_4 Esterase-like activity of phytase - - - 0.00000000002297 71.0
HKD1_k127_1280806_5 GDSL-like Lipase/Acylhydrolase - - - 0.0000004277 62.0
HKD1_k127_130605_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 1.413e-288 891.0
HKD1_k127_1312865_0 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 395.0
HKD1_k127_1312865_1 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 354.0
HKD1_k127_1322709_0 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 340.0
HKD1_k127_1322709_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000004763 154.0
HKD1_k127_1322709_2 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000001312 130.0
HKD1_k127_1340901_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 298.0
HKD1_k127_1340901_1 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003978 276.0
HKD1_k127_1340901_2 Mammalian cell entry related domain protein K02067,K06192 - - 0.000000000000000000000000000000000000000062 167.0
HKD1_k127_1340901_3 Dehydrogenase - - - 0.0000000000000000000000003271 121.0
HKD1_k127_1340901_4 Protein conserved in bacteria K18480 - - 0.00000000000001848 81.0
HKD1_k127_1340901_5 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000006677 68.0
HKD1_k127_1355184_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 445.0
HKD1_k127_1355184_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 432.0
HKD1_k127_1355184_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000004668 61.0
HKD1_k127_1360828_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1294.0
HKD1_k127_1360828_1 Protein of unknown function (DUF1329) - - - 0.000000000000000000000005273 110.0
HKD1_k127_1386736_0 protein involved in exopolysaccharide biosynthesis - - - 1.352e-218 713.0
HKD1_k127_1386736_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 535.0
HKD1_k127_1386736_10 - - - - 0.00000000001644 67.0
HKD1_k127_1386736_11 PFAM FecR protein - - - 0.0000008162 61.0
HKD1_k127_1386736_12 rod shape-determining protein MreD K03571 - - 0.00003546 55.0
HKD1_k127_1386736_13 PFAM Tetratricopeptide TPR2 - - - 0.0002115 50.0
HKD1_k127_1386736_2 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 524.0
HKD1_k127_1386736_3 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 367.0
HKD1_k127_1386736_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 333.0
HKD1_k127_1386736_5 MatE - - - 0.000000000000000000000000000000000000000000000000000000001962 217.0
HKD1_k127_1386736_6 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000002693 195.0
HKD1_k127_1386736_7 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000002054 160.0
HKD1_k127_1386736_8 cellulose binding - - - 0.000000000000000000000000000000001089 151.0
HKD1_k127_1386736_9 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000001704 96.0
HKD1_k127_1388418_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000005968 95.0
HKD1_k127_1388418_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000001932 89.0
HKD1_k127_1396842_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1301.0
HKD1_k127_1396842_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000003917 117.0
HKD1_k127_1410775_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 474.0
HKD1_k127_1410775_1 TIGRFAM hopanoid biosynthesis associated protein HpnK - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001009 254.0
HKD1_k127_1410775_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000823 243.0
HKD1_k127_1410775_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000003758 164.0
HKD1_k127_1410775_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000005529 148.0
HKD1_k127_1410775_5 lysyltransferase activity K07027 - - 0.00000000000000000000000000001729 130.0
HKD1_k127_1410775_6 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000659 102.0
HKD1_k127_1410775_7 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001744 99.0
HKD1_k127_1410775_8 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000008413 57.0
HKD1_k127_1436616_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 365.0
HKD1_k127_1436616_1 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000002097 190.0
HKD1_k127_1470308_0 Trehalose-phosphatase K16055 GO:0003674,GO:0003824,GO:0004805,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044464,GO:0046351,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:1901576 2.4.1.15,3.1.3.12 2.141e-200 650.0
HKD1_k127_1470308_1 transcription factor binding K15836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 570.0
HKD1_k127_1470308_2 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 501.0
HKD1_k127_1470308_3 Cytochrome b subunit of formate dehydrogenase-like protein - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016043,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051259,GO:0051260,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070813,GO:0070814,GO:0071840,GO:0097159,GO:1901363,GO:1903136 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 521.0
HKD1_k127_1470308_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000005367 195.0
HKD1_k127_1470308_5 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000001692 111.0
HKD1_k127_1470308_6 - - - - 0.000000000000002413 80.0
HKD1_k127_1470308_7 photoreceptor activity K11527 - 2.7.13.3 0.0000000000008824 78.0
HKD1_k127_1470308_8 hemerythrin HHE cation binding domain - - - 0.00000003598 67.0
HKD1_k127_1470308_9 PAS fold - - - 0.0000004409 57.0
HKD1_k127_1475647_0 Belongs to the RtcB family K14415 - 6.5.1.3 3.204e-215 680.0
HKD1_k127_1475647_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 571.0
HKD1_k127_1475647_2 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000004879 99.0
HKD1_k127_1476093_0 Catalase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 388.0
HKD1_k127_1476093_1 Acetyl-CoA acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 337.0
HKD1_k127_1476093_2 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000216 131.0
HKD1_k127_1476093_3 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000003895 84.0
HKD1_k127_1490431_0 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000001336 231.0
HKD1_k127_1490431_1 Phosphoesterase K07095 - - 0.0000000000000000000000000000000000000000000000000008786 198.0
HKD1_k127_1490431_2 Nitroreductase family - - - 0.000000000000000000000000000000000001402 146.0
HKD1_k127_1490431_3 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000004994 111.0
HKD1_k127_1490431_4 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000001747 102.0
HKD1_k127_1490431_5 negative regulation of translational initiation - - - 0.00002651 53.0
HKD1_k127_149181_0 CHAT domain - - - 0.0 1387.0
HKD1_k127_149181_1 Phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1200.0
HKD1_k127_149181_10 translation initiation factor activity K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001154 98.0
HKD1_k127_149181_12 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.0000001317 66.0
HKD1_k127_149181_2 Sugar (and other) transporter K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 507.0
HKD1_k127_149181_3 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 332.0
HKD1_k127_149181_4 Possible lysine decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005683 281.0
HKD1_k127_149181_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001324 266.0
HKD1_k127_149181_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000002594 222.0
HKD1_k127_149181_7 - K03561,K12287 - - 0.000000000000000000000000000000000001164 162.0
HKD1_k127_149181_8 Right handed beta helix region - - - 0.00000000000000000000000000000000001834 158.0
HKD1_k127_149181_9 VIT family - - - 0.00000000000000000000000000000000009474 149.0
HKD1_k127_1499468_0 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 481.0
HKD1_k127_1499468_1 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000589 263.0
HKD1_k127_1499468_2 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000000000000000000000000000000000107 239.0
HKD1_k127_1499468_3 alpha/beta hydrolase fold K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000009359 233.0
HKD1_k127_1499468_4 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000001674 223.0
HKD1_k127_1499468_5 Carboxylesterase family - - - 0.0000000000000000000000000000000000001914 153.0
HKD1_k127_1499468_6 YhhN family - - - 0.000000000000000000000006089 109.0
HKD1_k127_1499468_7 Histidine kinase - - - 0.000000000002873 79.0
HKD1_k127_150230_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 366.0
HKD1_k127_150230_1 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 294.0
HKD1_k127_150230_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000001201 261.0
HKD1_k127_150230_3 - - - - 0.00000000005432 64.0
HKD1_k127_1512773_0 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 484.0
HKD1_k127_1512773_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002446 267.0
HKD1_k127_1512773_2 Belongs to the enoyl-CoA hydratase isomerase family K07546 - - 0.0000000000000000000000000006068 120.0
HKD1_k127_1522166_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1475.0
HKD1_k127_1522166_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000005892 128.0
HKD1_k127_1522166_2 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000002302 107.0
HKD1_k127_1533836_0 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 366.0
HKD1_k127_1533836_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 366.0
HKD1_k127_1533836_2 MlaD protein K06192 - - 0.000000000000000000000000000000000000000000000001455 190.0
HKD1_k127_1533836_3 ABC-type transport auxiliary lipoprotein component K09857 - - 0.0000000000000000000004939 111.0
HKD1_k127_1560873_0 propanoyl-CoA C-acyltransferase activity K08764 GO:0000038,GO:0000062,GO:0000166,GO:0001676,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0003824,GO:0003988,GO:0005102,GO:0005215,GO:0005319,GO:0005488,GO:0005496,GO:0005504,GO:0005515,GO:0005548,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005777,GO:0005782,GO:0005783,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006699,GO:0006700,GO:0006701,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006886,GO:0006996,GO:0007031,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008207,GO:0008289,GO:0008306,GO:0008355,GO:0008525,GO:0008526,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009719,GO:0009725,GO:0009791,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010817,GO:0010876,GO:0010883,GO:0010888,GO:0010893,GO:0010941,GO:0010942,GO:0012505,GO:0014070,GO:0015031,GO:0015248,GO:0015485,GO:0015711,GO:0015748,GO:0015833,GO:0015850,GO:0015914,GO:0015918,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016137,GO:0016138,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0017127,GO:0017144,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019395,GO:0019637,GO:0019693,GO:0019748,GO:0019751,GO:0019752,GO:0019867,GO:0019898,GO:0022611,GO:0030258,GO:0030301,GO:0030554,GO:0031090,GO:0031312,GO:0031315,GO:0031406,GO:0031907,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032101,GO:0032355,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032377,GO:0032379,GO:0032380,GO:0032382,GO:0032383,GO:0032385,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032879,GO:0032934,GO:0032957,GO:0032958,GO:0032959,GO:0032991,GO:0033036,GO:0033218,GO:0033293,GO:0033365,GO:0033540,GO:0033559,GO:0033814,GO:0033865,GO:0033875,GO:0033993,GO:0034032,GO:0034440,GO:0034613,GO:0034641,GO:0034698,GO:0034699,GO:0034754,GO:0035383,GO:0036041,GO:0036042,GO:0036094,GO:0036109,GO:0036314,GO:0036315,GO:0040008,GO:0040012,GO:0040024,GO:0042048,GO:0042180,GO:0042181,GO:0042221,GO:0042445,GO:0042446,GO:0042448,GO:0042579,GO:0042802,GO:0042803,GO:0042810,GO:0042811,GO:0042886,GO:0042981,GO:0043053,GO:0043054,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043177,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043434,GO:0043436,GO:0043574,GO:0043603,GO:0043647,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044550,GO:0045184,GO:0045540,GO:0045542,GO:0045834,GO:0045927,GO:0045940,GO:0046165,GO:0046173,GO:0046394,GO:0046395,GO:0046483,GO:0046889,GO:0046890,GO:0046907,GO:0046982,GO:0046983,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048580,GO:0048582,GO:0048583,GO:0048638,GO:0048639,GO:0048856,GO:0050632,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050810,GO:0050877,GO:0050890,GO:0050896,GO:0050920,GO:0051049,GO:0051050,GO:0051094,GO:0051179,GO:0051186,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0055115,GO:0060341,GO:0060620,GO:0061062,GO:0061063,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070013,GO:0070538,GO:0070723,GO:0070727,GO:0070887,GO:0071310,GO:0071396,GO:0071397,GO:0071407,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071981,GO:0072329,GO:0072330,GO:0072521,GO:0072594,GO:0072657,GO:0072659,GO:0072662,GO:0072663,GO:0080090,GO:0090181,GO:0090205,GO:0090407,GO:0097159,GO:0097305,GO:0097306,GO:0097367,GO:0098588,GO:0098805,GO:0106118,GO:0106120,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901373,GO:1901564,GO:1901567,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901652,GO:1901657,GO:1901659,GO:1901681,GO:1901698,GO:1901700,GO:1901701,GO:1902930,GO:1902932,GO:1904069,GO:1904070,GO:1904109,GO:1904121,GO:1905952,GO:1905953,GO:1905954,GO:1990778,GO:2000026,GO:2000909,GO:2000911 2.3.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 497.0
HKD1_k127_1560873_1 N-acyl-D-aspartate D-glutamate deacylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 492.0
HKD1_k127_1560873_2 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000271 282.0
HKD1_k127_1560873_3 Domain of unknown function (DUF4336) - - - 0.00000000000000000000000000000000000000000000000000000000009792 214.0
HKD1_k127_1560873_4 Membrane dipeptidase (Peptidase family M19) - - - 0.0000000000000000001263 90.0
HKD1_k127_1560873_5 Fe-S-cluster oxidoreductase K06940 - - 0.000000000009996 70.0
HKD1_k127_1563959_0 Methionine synthase K00548 - 2.1.1.13 0.0 1064.0
HKD1_k127_157324_0 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 306.0
HKD1_k127_157324_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000008851 219.0
HKD1_k127_157684_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 532.0
HKD1_k127_157684_1 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 302.0
HKD1_k127_157684_2 Transporter associated domain - - - 0.00000000000000000000000000000000000000000001262 175.0
HKD1_k127_157684_3 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000003472 168.0
HKD1_k127_157684_4 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000001803 78.0
HKD1_k127_1584856_0 epimerase, PhzC PhzF homolog - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 298.0
HKD1_k127_1584856_1 Ferredoxin thioredoxin reductase catalytic beta chain K17892 - 1.8.7.2 0.000000000000000000000000000000000000000000000000000000000000000000003303 238.0
HKD1_k127_1584856_10 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000006963 133.0
HKD1_k127_1584856_11 PFAM toluene tolerance K07323 - - 0.0000000000000000000000009583 112.0
HKD1_k127_1584856_12 COG0208 Ribonucleotide reductase, beta subunit - - - 0.0000000000000000000006443 103.0
HKD1_k127_1584856_13 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000004439 86.0
HKD1_k127_1584856_2 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.000000000000000000000000000000000000000000000000000000000000000002001 235.0
HKD1_k127_1584856_3 Protein of unknown function (DUF1269) - - - 0.000000000000000000000000000000000000000000000000000000000000000004465 229.0
HKD1_k127_1584856_4 Psort location CytoplasmicMembrane, score 10.00 K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000002739 241.0
HKD1_k127_1584856_5 PFAM ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000008978 216.0
HKD1_k127_1584856_6 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000000000007604 193.0
HKD1_k127_1584856_7 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000003871 191.0
HKD1_k127_1584856_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000001562 169.0
HKD1_k127_1584856_9 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000009223 147.0
HKD1_k127_1625056_0 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000000000000000005548 125.0
HKD1_k127_1625056_1 amine dehydrogenase activity - - - 0.000000000211 71.0
HKD1_k127_162883_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 518.0
HKD1_k127_162883_1 Tetratricopeptide repeat - - - 0.000001457 59.0
HKD1_k127_1664169_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 520.0
HKD1_k127_1664169_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 479.0
HKD1_k127_1664169_2 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 437.0
HKD1_k127_1664169_3 L-carnitine dehydratase bile acid-inducible protein F K13607,K20882 - 2.8.3.17,2.8.3.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 387.0
HKD1_k127_1664169_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 364.0
HKD1_k127_1664169_5 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 367.0
HKD1_k127_1664169_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009211 252.0
HKD1_k127_1668784_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 625.0
HKD1_k127_1668784_1 Protein of unknown function (DUF1345) - - - 0.000000000000000000000000000000000000000000000000000001865 200.0
HKD1_k127_1668784_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000001215 189.0
HKD1_k127_1668784_3 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.000000000000000000000000000000000000000002175 161.0
HKD1_k127_1668784_4 - - - - 0.0000000000000000000000000777 112.0
HKD1_k127_1689876_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1069.0
HKD1_k127_1689876_1 PFAM Oxidoreductase FAD NAD(P)-binding K00380,K02641,K15511 - 1.14.13.208,1.18.1.2,1.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 354.0
HKD1_k127_1689876_2 Fasciclin - - - 0.00000000000000000000000006366 110.0
HKD1_k127_1714941_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001453 241.0
HKD1_k127_1721161_0 Biotin carboxylase C-terminal domain - - - 1.487e-279 876.0
HKD1_k127_1721161_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.101e-228 734.0
HKD1_k127_1721161_2 PFAM Enoyl-CoA hydratase isomerase K01692,K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 303.0
HKD1_k127_1721161_3 AAA ATPase domain - - - 0.00000000000000000001908 94.0
HKD1_k127_1721161_4 - - - - 0.0000000000000000003013 91.0
HKD1_k127_1721161_5 Sh3 type 3 domain protein - - - 0.0000000003315 73.0
HKD1_k127_1737018_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 433.0
HKD1_k127_1737018_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 400.0
HKD1_k127_1737018_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 347.0
HKD1_k127_1737018_3 Glycine cleavage H-protein K02437 - - 0.000000000000000000000000000000000000000000001167 168.0
HKD1_k127_1737018_4 Protein of unknown function (DUF559) - - - 0.000000000000000000000000000006989 121.0
HKD1_k127_1737018_5 Glycine cleavage system P-protein - - - 0.00000006605 54.0
HKD1_k127_175354_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 394.0
HKD1_k127_175354_1 KH domain K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 293.0
HKD1_k127_175354_2 Encapsulating protein for peroxidase - - - 0.000000000002084 67.0
HKD1_k127_1790709_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 369.0
HKD1_k127_1790709_1 META domain - - - 0.00000000000000000000002097 109.0
HKD1_k127_1790709_2 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.0005841 49.0
HKD1_k127_179496_0 AMP-binding enzyme K00666 GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0042546,GO:0042759,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0072330,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 406.0
HKD1_k127_179496_1 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 296.0
HKD1_k127_179496_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000003429 242.0
HKD1_k127_179496_3 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000003232 141.0
HKD1_k127_179496_4 AMP-binding enzyme K00666 - - 0.0000000000000008793 80.0
HKD1_k127_179496_5 - - - - 0.0000000001346 69.0
HKD1_k127_1825951_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1071.0
HKD1_k127_1825951_1 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000003549 230.0
HKD1_k127_1825951_2 glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.0000000000000000000000000000000000000000000000000000000000958 209.0
HKD1_k127_1825951_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000001425 210.0
HKD1_k127_1825951_4 sister chromatid segregation - - - 0.000000000000000000000000000000000000005072 156.0
HKD1_k127_1825951_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000007266 89.0
HKD1_k127_1825951_7 Domain of unknown function (DUF4410) - - - 0.0000000000002882 80.0
HKD1_k127_1827204_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 426.0
HKD1_k127_1827204_1 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 296.0
HKD1_k127_1865990_0 amino acid K03294 - - 1.305e-241 764.0
HKD1_k127_1865990_1 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 447.0
HKD1_k127_1865990_2 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 402.0
HKD1_k127_1865990_3 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000001954 237.0
HKD1_k127_1865990_4 Cysteine dioxygenase type I - - - 0.0000001685 62.0
HKD1_k127_1865990_5 FAD dependent oxidoreductase K09471 - - 0.0001312 47.0
HKD1_k127_187212_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 413.0
HKD1_k127_187212_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 377.0
HKD1_k127_187212_2 MFS/sugar transport protein K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007001 254.0
HKD1_k127_187212_3 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000001482 166.0
HKD1_k127_187212_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000001096 133.0
HKD1_k127_187212_5 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001237 130.0
HKD1_k127_187212_6 NlpE N-terminal domain - - - 0.0000000002485 67.0
HKD1_k127_1909246_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 437.0
HKD1_k127_1909246_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 394.0
HKD1_k127_1909246_2 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 375.0
HKD1_k127_1909246_3 pfam abc1 K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 329.0
HKD1_k127_1909246_4 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000002232 196.0
HKD1_k127_1909246_5 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000000000000006197 171.0
HKD1_k127_1909246_6 Putative restriction endonuclease - - - 0.00000000000000000000000000000000004407 140.0
HKD1_k127_1909246_7 MMPL family K07003 - - 0.00000000000000000000000002155 121.0
HKD1_k127_1913545_0 Belongs to the GPAT DAPAT family K00631 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002051 277.0
HKD1_k127_1918492_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1178.0
HKD1_k127_1918492_1 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 340.0
HKD1_k127_1918492_2 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 316.0
HKD1_k127_1918492_3 Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine K18911 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008213,GO:0008276,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0019439,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0036211,GO:0042398,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052707,GO:0052708,GO:0052709,GO:0052803,GO:0052805,GO:0071704,GO:0071944,GO:0097164,GO:0140096,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 303.0
HKD1_k127_1918492_4 ATPases associated with a variety of cellular activities K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 298.0
HKD1_k127_1918492_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000001259 129.0
HKD1_k127_1918492_6 Protein of unknown function (DUF721) - - - 0.00000000000000000000549 98.0
HKD1_k127_194852_0 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 356.0
HKD1_k127_194852_1 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004453 278.0
HKD1_k127_194852_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000001187 187.0
HKD1_k127_194852_3 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.000000000000000000000000000000000000004753 155.0
HKD1_k127_194852_4 TPR repeat - - - 0.00000000000028 82.0
HKD1_k127_1949168_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 360.0
HKD1_k127_1949168_1 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003656 286.0
HKD1_k127_1949168_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000003301 210.0
HKD1_k127_1949168_3 COG3909 Cytochrome c556 - - - 0.0000000000007576 81.0
HKD1_k127_19841_0 MOSC domain - - - 7.765e-256 800.0
HKD1_k127_19841_1 Belongs to the DEAD box helicase family K05592,K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 6.311e-213 676.0
HKD1_k127_19841_10 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000002027 153.0
HKD1_k127_19841_11 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000001315 134.0
HKD1_k127_19841_12 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000003974 106.0
HKD1_k127_19841_13 PFAM FUN14 family - - - 0.000000000002998 73.0
HKD1_k127_19841_14 Sporulation related domain - - - 0.00005973 56.0
HKD1_k127_19841_15 RING-variant domain - - - 0.000729 44.0
HKD1_k127_19841_2 oligoendopeptidase F K08602 - - 1.815e-203 649.0
HKD1_k127_19841_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 565.0
HKD1_k127_19841_4 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009786 506.0
HKD1_k127_19841_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 376.0
HKD1_k127_19841_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 313.0
HKD1_k127_19841_7 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005805 289.0
HKD1_k127_19841_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000001874 214.0
HKD1_k127_19841_9 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000003368 199.0
HKD1_k127_1986872_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.42e-213 676.0
HKD1_k127_1986872_1 hydrolase, family 1 K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 489.0
HKD1_k127_1986872_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 461.0
HKD1_k127_1986872_3 Phosphoinositide phospholipase C, Ca2+-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 376.0
HKD1_k127_1986872_4 NADPH quinone K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 305.0
HKD1_k127_2021611_0 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007256 540.0
HKD1_k127_2021611_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001154 242.0
HKD1_k127_2021611_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000001181 223.0
HKD1_k127_2021611_3 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000001178 189.0
HKD1_k127_2021611_4 PFAM Radical SAM - - - 0.00000000000000000000000000001526 132.0
HKD1_k127_2021611_5 - - - - 0.000000000002057 79.0
HKD1_k127_2029540_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 543.0
HKD1_k127_2029540_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 547.0
HKD1_k127_2029540_2 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 430.0
HKD1_k127_2029540_3 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002007 254.0
HKD1_k127_2029540_4 Gamma glutamyl transpeptidases K18592 - 2.3.2.2,3.4.19.13,3.4.19.14 0.000000000000000000000000000000000000000000000000000000000007648 214.0
HKD1_k127_2029540_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000009821 183.0
HKD1_k127_2029540_6 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000004886 161.0
HKD1_k127_2029540_7 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000004913 159.0
HKD1_k127_2029540_8 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000002674 76.0
HKD1_k127_2033185_0 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 464.0
HKD1_k127_2033185_1 Protein of unknown function (DUF1595) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009619 456.0
HKD1_k127_2033185_10 Tetratricopeptide repeat - - - 0.00000000000000002322 94.0
HKD1_k127_2033185_11 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.0000000002079 74.0
HKD1_k127_2033185_12 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000002085 61.0
HKD1_k127_2033185_13 - - - - 0.00004249 47.0
HKD1_k127_2033185_2 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 410.0
HKD1_k127_2033185_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000001008 220.0
HKD1_k127_2033185_4 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000006938 203.0
HKD1_k127_2033185_5 - - - - 0.000000000000000000000000000000000006501 152.0
HKD1_k127_2033185_6 Platelet-activating factor acetylhydrolase, isoform II - - - 0.00000000000000000000000000000008184 145.0
HKD1_k127_2033185_7 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.0000000000000000000000000503 112.0
HKD1_k127_2033185_8 - - - - 0.0000000000000000000000216 117.0
HKD1_k127_2033185_9 protein conserved in bacteria - - - 0.000000000000000009116 85.0
HKD1_k127_2037531_0 metallopeptidase activity - - - 4.499e-244 781.0
HKD1_k127_2037531_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000006224 125.0
HKD1_k127_206341_0 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 413.0
HKD1_k127_206341_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 339.0
HKD1_k127_206341_2 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000006076 189.0
HKD1_k127_206341_3 Right handed beta helix region - - - 0.0000000000000000000000000000000000000006828 163.0
HKD1_k127_206341_4 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000000000000000003679 124.0
HKD1_k127_207370_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 406.0
HKD1_k127_207370_1 Phosphoinositide phospholipase C, Ca2+-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 402.0
HKD1_k127_207370_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 290.0
HKD1_k127_207370_3 - - - - 0.00000000000000000000000000000000000000000000000000000000002811 229.0
HKD1_k127_207370_4 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000001626 187.0
HKD1_k127_2076550_0 transferase activity, transferring glycosyl groups K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000008001 232.0
HKD1_k127_2076550_1 Pfam Glycosyl transferase family 2 K16556 - - 0.00000000000000000000000000000000000000000000002531 190.0
HKD1_k127_2076550_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000004507 162.0
HKD1_k127_2076550_3 Las17-binding protein actin regulator - - - 0.00000000000000000006842 98.0
HKD1_k127_2076550_4 PFAM Ig domain protein group 2 domain protein - - - 0.0000000008459 68.0
HKD1_k127_2076550_5 Belongs to the peptidase S8 family - - - 0.0000002342 61.0
HKD1_k127_2087897_0 (mono)amine oxidase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 395.0
HKD1_k127_2087897_1 Glycosyl transferases group 1 - - - 0.000000000000000000000001027 120.0
HKD1_k127_2087897_2 PFAM Glycosyl transferase family 2 - - - 0.00000000004175 75.0
HKD1_k127_2091969_0 Glycoside hydrolase family 44 - - - 2.096e-197 648.0
HKD1_k127_2091969_1 UbiE COQ5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 332.0
HKD1_k127_2091969_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005573 280.0
HKD1_k127_2091969_3 PFAM methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000005426 231.0
HKD1_k127_2091969_4 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.0000000000000000000000000000000000000000000000000001547 192.0
HKD1_k127_2091969_5 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000002443 190.0
HKD1_k127_2091969_6 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000006949 180.0
HKD1_k127_2091969_7 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000008526 184.0
HKD1_k127_2091969_8 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000001662 157.0
HKD1_k127_2091969_9 alpha-L-arabinofuranosidase - - - 0.000003984 61.0
HKD1_k127_2093170_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 2.652e-286 903.0
HKD1_k127_2093170_1 PFAM ABC transporter, transmembrane region K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 581.0
HKD1_k127_2093170_2 Flavodoxin-like fold K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 300.0
HKD1_k127_2093170_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000001295 235.0
HKD1_k127_2093170_4 transferase activity, transferring glycosyl groups - - - 0.000000000004861 68.0
HKD1_k127_2095274_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000005867 240.0
HKD1_k127_2095812_0 COG0788 Formyltetrahydrofolate hydrolase K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003798 287.0
HKD1_k127_2095812_1 4 iron, 4 sulfur cluster binding K05524 GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - 0.000000000000000000000000000000000003713 140.0
HKD1_k127_2095812_2 Belongs to the ompA family K03286 - - 0.00000000000000000000000000004083 127.0
HKD1_k127_2095812_3 Protein of unknown function (DUF1329) - - - 0.000000000000000000001705 103.0
HKD1_k127_2095812_4 Transcriptional regulator - - - 0.000000000000000005285 92.0
HKD1_k127_210219_0 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 510.0
HKD1_k127_210219_1 PFAM 2-nitropropane dioxygenase NPD K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 350.0
HKD1_k127_210219_3 Short-chain dehydrogenase reductase sdr K14633 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001901 263.0
HKD1_k127_210219_4 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000002674 241.0
HKD1_k127_210219_5 Transcriptional - - - 0.00000000000000000000000000000000000000000000000000000001171 219.0
HKD1_k127_210219_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000002175 115.0
HKD1_k127_210219_7 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000276 83.0
HKD1_k127_210219_8 F420-dependent oxidoreductase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000001815 70.0
HKD1_k127_2114522_0 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 476.0
HKD1_k127_2114522_1 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 430.0
HKD1_k127_2114522_10 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000002424 194.0
HKD1_k127_2114522_11 quinone binding K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000001442 171.0
HKD1_k127_2114522_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000002316 172.0
HKD1_k127_2114522_13 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000002125 140.0
HKD1_k127_2114522_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000038 129.0
HKD1_k127_2114522_15 dTDP-4-dehydrorhamnose 3,5-epimerase activity K00067,K01710,K01790 - 1.1.1.133,4.2.1.46,5.1.3.13 0.0000000000000000000000000000002234 139.0
HKD1_k127_2114522_16 Transcription factor zinc-finger K09981 - - 0.00000000009201 72.0
HKD1_k127_2114522_2 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 399.0
HKD1_k127_2114522_3 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008926 277.0
HKD1_k127_2114522_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000004269 239.0
HKD1_k127_2114522_5 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000002036 231.0
HKD1_k127_2114522_6 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000005329 230.0
HKD1_k127_2114522_7 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000002091 202.0
HKD1_k127_2114522_8 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000002638 206.0
HKD1_k127_2114522_9 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000007511 181.0
HKD1_k127_2138671_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 5.672e-271 853.0
HKD1_k127_2138671_1 acyl-CoA dehydrogenase - - - 1.263e-217 684.0
HKD1_k127_2138671_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000001368 166.0
HKD1_k127_2138671_11 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000005977 147.0
HKD1_k127_2138671_12 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000000000000000001316 123.0
HKD1_k127_2138671_13 - - - - 0.000000000000005819 81.0
HKD1_k127_2138671_14 NIL domain - - - 0.00000000000009683 83.0
HKD1_k127_2138671_15 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000001468 69.0
HKD1_k127_2138671_16 AntiSigma factor - - - 0.0003498 50.0
HKD1_k127_2138671_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.102e-201 658.0
HKD1_k127_2138671_3 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 547.0
HKD1_k127_2138671_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01883,K12339 - 2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 361.0
HKD1_k127_2138671_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 338.0
HKD1_k127_2138671_6 transport system involved in gliding motility, auxiliary K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 325.0
HKD1_k127_2138671_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004042 277.0
HKD1_k127_2138671_8 PFAM UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000173 232.0
HKD1_k127_2138671_9 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000001908 213.0
HKD1_k127_2144068_0 sulfate adenylyltransferase K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 492.0
HKD1_k127_2144068_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 419.0
HKD1_k127_2144068_2 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 306.0
HKD1_k127_2144068_3 PFAM ABC transporter related K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 293.0
HKD1_k127_2145298_0 Transglycosylase - - - 7.353e-248 799.0
HKD1_k127_2145298_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 5.057e-215 675.0
HKD1_k127_2145298_2 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 591.0
HKD1_k127_2145298_3 COG0625 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 394.0
HKD1_k127_2145298_4 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006227 263.0
HKD1_k127_2145298_5 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000001289 240.0
HKD1_k127_2151362_0 response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002066 264.0
HKD1_k127_2151362_1 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000000000003938 177.0
HKD1_k127_2152276_0 Allophanate hydrolase subunit 1 K01941 - 6.3.4.6 0.0 1137.0
HKD1_k127_2152276_1 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 349.0
HKD1_k127_2152276_2 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 336.0
HKD1_k127_2152444_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00322,K00382 - 1.6.1.1,1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 486.0
HKD1_k127_2152444_1 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000005566 143.0
HKD1_k127_216248_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000004975 248.0
HKD1_k127_216248_1 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000002732 222.0
HKD1_k127_216248_2 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.0000000000000000000000000000000000000000000000000000000003869 216.0
HKD1_k127_216248_3 transcriptional regulator - - - 0.00000000000000000000000000000000002372 152.0
HKD1_k127_216248_4 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000001189 67.0
HKD1_k127_216248_5 Cupin 2, conserved barrel domain protein - - - 0.0000004251 58.0
HKD1_k127_2171516_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 522.0
HKD1_k127_2171516_1 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 491.0
HKD1_k127_2171516_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 372.0
HKD1_k127_2171516_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000001438 252.0
HKD1_k127_2171516_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005891 264.0
HKD1_k127_2171516_5 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000001954 109.0
HKD1_k127_220647_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 431.0
HKD1_k127_220647_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 319.0
HKD1_k127_220647_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000001011 243.0
HKD1_k127_220647_3 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000002443 188.0
HKD1_k127_220647_4 transcriptional regulator - - - 0.000000000000000000000000000000002396 137.0
HKD1_k127_220647_5 Nodulation protein S (NodS) - - - 0.000000000000000000000000000003004 128.0
HKD1_k127_220647_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00001065 52.0
HKD1_k127_2224993_0 FG-GAP repeat - - - 0.000000000000007221 89.0
HKD1_k127_2224993_1 amine dehydrogenase activity - - - 0.0009913 49.0
HKD1_k127_2225696_0 COG2211 Na melibiose symporter and related transporters K03292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 353.0
HKD1_k127_2225696_1 HIT domain K02503 - - 0.000000000000000000000000000000000000000000000173 172.0
HKD1_k127_2234870_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 6.26e-216 681.0
HKD1_k127_2234870_1 General secretory system II, protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001562 252.0
HKD1_k127_2234870_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000009769 220.0
HKD1_k127_2236082_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1010.0
HKD1_k127_2236082_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001174 267.0
HKD1_k127_2236082_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.0000000000000000003534 87.0
HKD1_k127_2236604_0 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000001716 207.0
HKD1_k127_2236604_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000001025 163.0
HKD1_k127_2236604_2 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000001659 111.0
HKD1_k127_2236604_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000189 57.0
HKD1_k127_2273788_0 synthetase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000657 279.0
HKD1_k127_2273788_1 haloacid dehalogenase K01091 - 3.1.3.18 0.000000000000000006752 97.0
HKD1_k127_2278241_0 radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 559.0
HKD1_k127_2278241_1 Peptidase family M28 - - - 0.0000000000000000003417 99.0
HKD1_k127_2294908_0 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 8.048e-260 823.0
HKD1_k127_2294908_1 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 602.0
HKD1_k127_2294908_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003034 282.0
HKD1_k127_2294908_3 Outer Membrane Lipoprotein K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005542 261.0
HKD1_k127_2294908_4 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000000000000185 202.0
HKD1_k127_2294908_6 - - - - 0.00000002025 62.0
HKD1_k127_2295855_0 PFAM ROK family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002289 258.0
HKD1_k127_2306338_0 L-carnitine dehydratase bile acid-inducible protein F - - - 3.057e-254 807.0
HKD1_k127_2306338_1 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 358.0
HKD1_k127_2306338_2 Aminotransferase K00814,K14260 GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0040007,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 361.0
HKD1_k127_2306338_3 metal-dependent hydrolase of the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000001087 233.0
HKD1_k127_2306338_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000006678 130.0
HKD1_k127_2324230_0 ATPase activity K02013,K09817 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000009449 256.0
HKD1_k127_2324230_1 ABC 3 transport family K02075,K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007919 265.0
HKD1_k127_2324429_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 320.0
HKD1_k127_2324429_1 - - - - 0.00009197 52.0
HKD1_k127_2330953_0 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K15060 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 522.0
HKD1_k127_2330953_1 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001083 239.0
HKD1_k127_2339713_0 SbmA/BacA-like family K02471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 464.0
HKD1_k127_2339713_1 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 384.0
HKD1_k127_2339713_2 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008856 303.0
HKD1_k127_2339713_3 PFAM Transglycosylase-associated protein - - - 0.0000000000000000000000000000005692 123.0
HKD1_k127_233977_0 PFAM Glycosyl hydrolase family 1 K01223,K05350 - 3.2.1.21,3.2.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 522.0
HKD1_k127_233977_1 Transposase IS200 like - - - 0.00000000000000000002764 97.0
HKD1_k127_233977_2 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K07004 - 3.4.24.40 0.0000000000000007179 88.0
HKD1_k127_233977_3 Tellurite resistance protein TerB K05801 - - 0.0000000006281 69.0
HKD1_k127_233977_4 NUDIX domain - - - 0.000000003362 70.0
HKD1_k127_233977_5 Protein of unknown function (DUF1232) - - - 0.000034 54.0
HKD1_k127_2342101_0 Sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 605.0
HKD1_k127_2342101_1 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 312.0
HKD1_k127_2342101_2 - - - - 0.0000000000000000000000000000000000000000000000004186 197.0
HKD1_k127_2342101_3 Cysteine rich repeat - - - 0.000000859 55.0
HKD1_k127_2342475_0 Type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 329.0
HKD1_k127_2342475_1 Shikimate kinase K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000002284 124.0
HKD1_k127_2344640_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 407.0
HKD1_k127_2344640_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000002605 177.0
HKD1_k127_2344640_2 PFAM Glycosyl transferase family 2 K00752 - 2.4.1.212 0.000000000000000000000000000000000000000000005876 180.0
HKD1_k127_2344640_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000003777 139.0
HKD1_k127_2344640_4 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000266 117.0
HKD1_k127_2344640_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000003815 79.0
HKD1_k127_2344640_6 - - - - 0.000000000000006251 86.0
HKD1_k127_2386284_0 DoxX-like family - - - 0.0000000000000000000000000000000000000003337 153.0
HKD1_k127_2386284_1 DNA-templated transcription, initiation K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090 - 0.00000000000000000000000000000000000005918 158.0
HKD1_k127_2386284_2 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000002023 145.0
HKD1_k127_2386284_3 ChrR Cupin-like domain - - - 0.0000000000000003734 91.0
HKD1_k127_2386284_4 Anti-sigma-K factor rskA - - - 0.00000007749 61.0
HKD1_k127_2408511_0 R3H domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 564.0
HKD1_k127_2408511_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000001739 157.0
HKD1_k127_2408511_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000006689 87.0
HKD1_k127_2408511_3 Cysteine-rich domain - - - 0.000000000009171 71.0
HKD1_k127_2408511_4 ATPase family associated with various cellular activities (AAA) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.0000000351 58.0
HKD1_k127_2413165_0 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 365.0
HKD1_k127_2413165_1 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 349.0
HKD1_k127_2413165_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 326.0
HKD1_k127_2413165_3 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000009225 183.0
HKD1_k127_2413165_4 SnoaL-like domain - - - 0.0000000000000000000000000000000000000741 147.0
HKD1_k127_2413165_5 EamA-like transporter family - - - 0.00000000000000000000001614 111.0
HKD1_k127_2423960_0 STAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 546.0
HKD1_k127_2423960_1 amino acid-binding ACT domain protein K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 427.0
HKD1_k127_2423960_2 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 369.0
HKD1_k127_2439151_0 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 443.0
HKD1_k127_2439151_1 - - - - 0.00000000000000000000000000001237 131.0
HKD1_k127_2439151_2 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000008844 119.0
HKD1_k127_2439151_3 Mo-molybdopterin cofactor biosynthetic process - - - 0.00000000000001901 83.0
HKD1_k127_2439151_4 Glyoxalase-like domain K01759 - 4.4.1.5 0.000000003826 63.0
HKD1_k127_2439151_5 alcohol dehydrogenase K00001,K13953,K13979 - 1.1.1.1 0.00000001392 55.0
HKD1_k127_2444932_0 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 381.0
HKD1_k127_2444932_1 inositol monophosphatase K01092,K05602 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008934,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016053,GO:0016137,GO:0016138,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052745,GO:0052803,GO:0052834,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659 3.1.3.15,3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000004734 250.0
HKD1_k127_2444932_2 SnoaL-like domain - - - 0.00000009611 60.0
HKD1_k127_2446047_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 5.963e-313 1000.0
HKD1_k127_2446047_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 349.0
HKD1_k127_2446047_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 304.0
HKD1_k127_2446047_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 306.0
HKD1_k127_2446047_4 Protein of unknown function (DUF1329) - - - 0.000000000000000000005127 108.0
HKD1_k127_2446047_5 Lamin Tail Domain - - - 0.0001049 55.0
HKD1_k127_2450620_0 SpoVR family K06415 - - 1.931e-199 637.0
HKD1_k127_2450620_1 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 532.0
HKD1_k127_2450620_2 PrkA AAA domain K07180 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001453 267.0
HKD1_k127_2450620_3 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002585 267.0
HKD1_k127_245881_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001698 287.0
HKD1_k127_245881_1 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006244 264.0
HKD1_k127_245881_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 0.00000000000000000000000000000000000000000000000000000000000000000006488 252.0
HKD1_k127_245881_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000006298 184.0
HKD1_k127_245881_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.00000000000000000000000000000000000000001216 165.0
HKD1_k127_245881_5 PFAM phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000006742 115.0
HKD1_k127_245881_6 Protein conserved in bacteria K09986 - - 0.00000000000000000005535 100.0
HKD1_k127_245881_7 Histidine kinase - - - 0.0000000000000003907 81.0
HKD1_k127_245881_8 Dual specificity phosphatase, catalytic domain K14165 - 3.1.3.16,3.1.3.48 0.000000000000001356 90.0
HKD1_k127_245881_9 transcriptional regulator - - - 0.00000000000001951 81.0
HKD1_k127_2459811_0 GMC oxidoreductase - - - 7.167e-248 774.0
HKD1_k127_2459811_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 405.0
HKD1_k127_2459811_2 PEP-CTERM motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 319.0
HKD1_k127_2459811_3 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 309.0
HKD1_k127_2459811_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002446 226.0
HKD1_k127_2459811_5 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000009186 210.0
HKD1_k127_2459811_6 - - - - 0.000000000001418 81.0
HKD1_k127_2460479_0 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000006143 175.0
HKD1_k127_2460479_1 ECF sigma factor K03088 - - 0.000000000000000000001839 101.0
HKD1_k127_2460479_2 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000001176 79.0
HKD1_k127_2460479_3 ATP-independent chaperone mediated protein folding K06006 - - 0.0000006544 61.0
HKD1_k127_2467699_0 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426 324.0
HKD1_k127_2467699_1 - - - - 0.0000000000000007969 80.0
HKD1_k127_2467699_2 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.000000001387 65.0
HKD1_k127_2496838_0 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 524.0
HKD1_k127_2496838_1 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000006939 179.0
HKD1_k127_2518827_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.499e-303 943.0
HKD1_k127_2518827_1 alpha-glucan phosphorylase K00688 - 2.4.1.1 6.844e-232 740.0
HKD1_k127_2518827_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001343 291.0
HKD1_k127_2518827_3 CorA-like Mg2+ transporter protein K16074 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000008295 254.0
HKD1_k127_2518827_4 serine protease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000055 248.0
HKD1_k127_2518827_5 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000007817 233.0
HKD1_k127_252218_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 354.0
HKD1_k127_252218_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 316.0
HKD1_k127_252218_2 CDP-alcohol phosphatidyltransferase K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.00000000005376 72.0
HKD1_k127_254248_0 PFAM Glycosyl transferase family 2 K16557 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000008964 187.0
HKD1_k127_254248_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000003717 150.0
HKD1_k127_2572076_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 5.196e-244 765.0
HKD1_k127_2572076_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 597.0
HKD1_k127_2572076_10 Biotin carboxylase C-terminal domain K01968 - 6.4.1.4 0.0000000002343 74.0
HKD1_k127_2572076_2 PFAM Carbamoyl-phosphate synthase L chain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 507.0
HKD1_k127_2572076_3 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 305.0
HKD1_k127_2572076_4 Electron transfer flavoprotein, beta subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 292.0
HKD1_k127_2572076_5 regulatory protein IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 292.0
HKD1_k127_2572076_6 Methionyl-tRNA formyltransferase K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000002454 263.0
HKD1_k127_2572076_7 Thi4 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001183 250.0
HKD1_k127_2572076_8 BAAT / Acyl-CoA thioester hydrolase C terminal K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000003047 228.0
HKD1_k127_2572076_9 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000001003 163.0
HKD1_k127_2588597_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.492e-204 645.0
HKD1_k127_2588597_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 608.0
HKD1_k127_2588597_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000004784 92.0
HKD1_k127_2588597_11 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.000000000000007718 83.0
HKD1_k127_2588597_2 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 546.0
HKD1_k127_2588597_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 423.0
HKD1_k127_2588597_4 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 379.0
HKD1_k127_2588597_5 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000003619 203.0
HKD1_k127_2588597_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000001036 177.0
HKD1_k127_2588597_7 Cupredoxin-like domain K02275 - 1.9.3.1 0.00000000000000000000000002361 111.0
HKD1_k127_2588597_8 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000000001045 110.0
HKD1_k127_2588597_9 Na+/H+ ion antiporter subunit K05562,K05569 - - 0.000000000000000000004984 108.0
HKD1_k127_2589689_0 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000607 291.0
HKD1_k127_2589689_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000001836 151.0
HKD1_k127_2589689_2 PFAM glycosyl transferase family 39 - - - 0.00000000003426 77.0
HKD1_k127_2589689_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000005189 53.0
HKD1_k127_2597994_0 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 355.0
HKD1_k127_2597994_1 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 310.0
HKD1_k127_2597994_2 Lactamase, beta 2 - GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0031974,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000003904 212.0
HKD1_k127_2597994_3 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000001623 134.0
HKD1_k127_2597994_4 MmgE/PrpD family - - - 0.00000000000000000000000000002636 133.0
HKD1_k127_2597994_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000003795 101.0
HKD1_k127_2608263_0 DNA polymerase IV (family X) K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 550.0
HKD1_k127_2608263_1 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000002343 204.0
HKD1_k127_2608263_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000008678 172.0
HKD1_k127_2608263_3 of nitrite reductase and ring-hydroxylating dioxygenase K00363,K05710 - 1.7.1.15 0.0000000000000000000000000004383 117.0
HKD1_k127_2608263_4 - - - - 0.00006562 55.0
HKD1_k127_2623336_0 TIGRFAM type I secretion membrane fusion protein, HlyD family K11003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 423.0
HKD1_k127_2623336_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 332.0
HKD1_k127_2629271_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 320.0
HKD1_k127_2629271_1 lysozyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001628 306.0
HKD1_k127_2671688_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1361.0
HKD1_k127_2671688_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000004649 103.0
HKD1_k127_267879_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 6.555e-262 816.0
HKD1_k127_267879_1 GTP-binding protein TypA K06207 - - 2.031e-246 776.0
HKD1_k127_267879_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 507.0
HKD1_k127_267879_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 389.0
HKD1_k127_267879_4 Glucose sorbosone - - - 0.00000002818 63.0
HKD1_k127_2685170_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 533.0
HKD1_k127_2685170_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 408.0
HKD1_k127_2685170_2 Cytochrome C oxidase subunit II, periplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001059 248.0
HKD1_k127_2685170_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000044 189.0
HKD1_k127_2685170_4 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000004412 171.0
HKD1_k127_2685381_0 Arginine K01478 - 3.5.3.6 1.245e-249 773.0
HKD1_k127_2685381_1 Amino acid permease K03758 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 609.0
HKD1_k127_2685381_2 Amino acid permease K03294,K03758,K03759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 592.0
HKD1_k127_2685381_3 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 398.0
HKD1_k127_2685381_4 UPF0056 inner membrane protein K05595 - - 0.0000000000000000000000000000000000001486 160.0
HKD1_k127_2685381_5 Na+/H+ antiporter family - - - 0.00000000000000000000009891 98.0
HKD1_k127_2694791_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 317.0
HKD1_k127_2694791_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001044 284.0
HKD1_k127_2694791_2 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000000000000000000001207 237.0
HKD1_k127_2694791_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000004786 159.0
HKD1_k127_2704722_0 Citrate lyase, alpha subunit (CitF) K01643 - 2.8.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 442.0
HKD1_k127_2704722_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003313 279.0
HKD1_k127_2704722_2 Domain of unknown function (DUF296) K06934 - - 0.0000000000000000000000000000007182 128.0
HKD1_k127_2704722_3 Covalent carrier of the coenzyme of citrate lyase K01646 - - 0.00000000000000000000005135 99.0
HKD1_k127_2704722_4 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.00000000000004815 72.0
HKD1_k127_2733605_0 Sodium/calcium exchanger protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 552.0
HKD1_k127_2733605_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 418.0
HKD1_k127_2733605_2 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004623 280.0
HKD1_k127_2733605_3 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000000000001598 168.0
HKD1_k127_2733605_4 Acetyl-CoA acetyltransferase - - - 0.00000000000000000004628 90.0
HKD1_k127_2733605_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.000003608 58.0
HKD1_k127_2737209_0 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 493.0
HKD1_k127_2737209_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006621 394.0
HKD1_k127_2737209_2 Cytochrome c K00406,K03889,K17222,K19713 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000005971 262.0
HKD1_k127_2737209_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000005322 267.0
HKD1_k127_2737209_4 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000005088 156.0
HKD1_k127_2737209_5 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000001777 143.0
HKD1_k127_2737209_7 Periplasmic binding protein - - - 0.00001218 54.0
HKD1_k127_2745792_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.592e-196 619.0
HKD1_k127_2745792_1 C-terminal, D2-small domain, of ClpB protein K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 565.0
HKD1_k127_2745792_10 Dihydrodipicolinate reductase, C-terminus K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000002086 254.0
HKD1_k127_2745792_11 - - - - 0.0000000000000004073 91.0
HKD1_k127_2745792_12 Fibronectin type 3 domain - - - 0.00000001702 63.0
HKD1_k127_2745792_13 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.0001282 51.0
HKD1_k127_2745792_2 argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 535.0
HKD1_k127_2745792_3 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 442.0
HKD1_k127_2745792_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 382.0
HKD1_k127_2745792_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 397.0
HKD1_k127_2745792_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 333.0
HKD1_k127_2745792_7 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 343.0
HKD1_k127_2745792_8 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001878 264.0
HKD1_k127_2745792_9 Proteasome subunit K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000001365 248.0
HKD1_k127_275026_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 334.0
HKD1_k127_275026_1 - - - - 0.0000000000000000000000000000000007439 137.0
HKD1_k127_275026_2 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000001688 132.0
HKD1_k127_275026_3 flavin adenine dinucleotide binding - - - 0.000000007223 59.0
HKD1_k127_2766085_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 471.0
HKD1_k127_2766085_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000009062 269.0
HKD1_k127_2766085_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000001225 95.0
HKD1_k127_2766085_3 Domain of unknown function (DUF4215) - - - 0.0000002051 59.0
HKD1_k127_2777687_0 Pfam:CPSase_L_chain - - - 0.0 1058.0
HKD1_k127_2777687_1 Carboxyl transferase domain - - - 5.608e-254 794.0
HKD1_k127_2777687_2 alginic acid biosynthetic process - - - 0.00001145 59.0
HKD1_k127_2802322_0 Membrane - - - 0.0000000009095 68.0
HKD1_k127_2802322_1 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.000004807 51.0
HKD1_k127_2815701_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 8.576e-248 780.0
HKD1_k127_2815701_1 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 425.0
HKD1_k127_2815701_2 TonB-dependent Receptor Plug Domain K16092 - - 0.000000000000000000000000000000000000000000000000000000003694 230.0
HKD1_k127_2855042_0 Glycosyl transferase family 21 K03669 - - 2.852e-219 692.0
HKD1_k127_2855042_1 Glycosyltransferase 36 associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 574.0
HKD1_k127_2855042_2 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 377.0
HKD1_k127_2855042_3 Protein of unknown function (DUF3131) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 312.0
HKD1_k127_2855042_4 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 290.0
HKD1_k127_2855042_5 SURF4 family K15977 - - 0.000000000001008 75.0
HKD1_k127_288581_0 Belongs to the peptidase S16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 520.0
HKD1_k127_2893712_1 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 516.0
HKD1_k127_2893712_2 Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 288.0
HKD1_k127_2893712_3 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005145 282.0
HKD1_k127_2893712_4 Methylamine dehydrogenase, L chain K15228 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000023 238.0
HKD1_k127_2893712_5 methylamine dehydrogenase accessory protein MauD - - - 0.000000000000000000000000000000000000000000000000000000003111 207.0
HKD1_k127_2893712_6 Methylamine utilisation protein MauE - - - 0.0000000000000000000000000001555 132.0
HKD1_k127_2893712_7 Cytochrome c - - - 0.00000000000000000000001115 112.0
HKD1_k127_293050_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 493.0
HKD1_k127_293050_1 Cytochrome P450 K17474 - 1.14.15.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 360.0
HKD1_k127_293050_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000006818 229.0
HKD1_k127_293050_3 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - 0.0000001925 59.0
HKD1_k127_2934263_0 Dehydratase family K01687 - 4.2.1.9 1.836e-251 790.0
HKD1_k127_2934263_1 desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 349.0
HKD1_k127_2934263_2 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000001417 224.0
HKD1_k127_2934263_3 Cold-shock protein K03704 - - 0.000000000000000000000000003256 113.0
HKD1_k127_2947123_0 CTP synthase N-terminus K01937 - 6.3.4.2 1.959e-229 718.0
HKD1_k127_2947123_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 484.0
HKD1_k127_2947123_2 Cytidylyltransferase K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 295.0
HKD1_k127_2947123_3 Sodium Bile acid symporter family - - - 0.0000000000000000000000000006759 132.0
HKD1_k127_2947123_4 Carboxymuconolactone decarboxylase family - - - 0.00000000000176 69.0
HKD1_k127_2972932_0 Pyridoxal-phosphate dependent enzyme K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 512.0
HKD1_k127_2972932_1 COG0534 Na -driven multidrug efflux pump K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 400.0
HKD1_k127_2972932_2 NAD binding K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 381.0
HKD1_k127_2972932_3 NAD-dependent epimerase - - - 0.000000000000000000000000000000000000000000000000000000000001054 218.0
HKD1_k127_2972932_4 Endonuclease/Exonuclease/phosphatase family K12351 GO:0000322,GO:0000323,GO:0000324,GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005773,GO:0005783,GO:0005886,GO:0006629,GO:0006643,GO:0006665,GO:0006672,GO:0006807,GO:0006950,GO:0006970,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009628,GO:0009651,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0019867,GO:0030148,GO:0030149,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031306,GO:0031307,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032592,GO:0032995,GO:0034641,GO:0042578,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043604,GO:0044087,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044271,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0046466,GO:0046467,GO:0046513,GO:0046519,GO:0046521,GO:0050789,GO:0050794,GO:0050896,GO:0052712,GO:0052713,GO:0052714,GO:0065007,GO:0071704,GO:0071944,GO:0097164,GO:0098573,GO:0098588,GO:0098805,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1903338 3.1.4.12 0.00003137 55.0
HKD1_k127_2983260_0 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000003451 167.0
HKD1_k127_298833_0 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 599.0
HKD1_k127_298833_1 AMP-binding enzyme C-terminal domain K04116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 403.0
HKD1_k127_298833_2 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000000000000000000000000000005563 188.0
HKD1_k127_298833_3 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992,K19341 - - 0.000000000000000000000000000000001607 140.0
HKD1_k127_298833_4 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000006437 78.0
HKD1_k127_299078_0 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 564.0
HKD1_k127_299078_1 Protein of unknown function (DUF3604) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 548.0
HKD1_k127_299078_2 Acetolactate synthase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004903 289.0
HKD1_k127_299078_3 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.000000000000000000000000000000000000000000000000003216 198.0
HKD1_k127_3003498_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 468.0
HKD1_k127_3003498_1 STELLO glycosyltransferases - - - 0.0000000000000000000000000000000000000000000000000003409 192.0
HKD1_k127_3003498_2 SMART Prolyl 4-hydroxylase, alpha subunit - - - 0.000000000000000000000000000000000001974 160.0
HKD1_k127_3003498_3 - - - - 0.00000000000000000000001083 119.0
HKD1_k127_3003498_4 Sulfotransferase family - - - 0.0000000000003113 79.0
HKD1_k127_3003498_5 - - - - 0.0000000005413 72.0
HKD1_k127_3003498_6 Glycosyl transferase, family 2 - - - 0.0002419 54.0
HKD1_k127_3021318_0 Bacterial regulatory protein, Fis family K11384 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 604.0
HKD1_k127_3021318_1 Histidine kinase K11383 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 562.0
HKD1_k127_3021318_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 514.0
HKD1_k127_3021318_3 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 339.0
HKD1_k127_3021318_4 MerR, DNA binding K13639 - - 0.000000000000000000000000000000000000000000000000000000001587 204.0
HKD1_k127_3028088_0 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000008945 196.0
HKD1_k127_3032325_0 COG0659 Sulfate permease and related transporters (MFS superfamily) K01673,K03321 - 4.2.1.1 2.544e-204 651.0
HKD1_k127_3032325_1 PFAM monooxygenase FAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002658 279.0
HKD1_k127_3032325_2 glyoxalase III activity - - - 0.000000000000000000000000000000000000000062 167.0
HKD1_k127_3032325_3 Hep Hag repeat protein K01406,K21449 - 3.4.24.40 0.0000000000000000000000005143 123.0
HKD1_k127_3032325_4 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000004639 81.0
HKD1_k127_3032325_5 Involved in the tonB-independent uptake of proteins - - - 0.0000002402 60.0
HKD1_k127_3032325_6 Male sterility protein - - - 0.0002061 44.0
HKD1_k127_305086_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 5.36e-197 621.0
HKD1_k127_305086_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 468.0
HKD1_k127_305086_10 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000134 207.0
HKD1_k127_305086_11 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002869 209.0
HKD1_k127_305086_12 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000004171 204.0
HKD1_k127_305086_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000002037 188.0
HKD1_k127_305086_14 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000002003 181.0
HKD1_k127_305086_15 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000008036 172.0
HKD1_k127_305086_16 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000009073 164.0
HKD1_k127_305086_17 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000001497 163.0
HKD1_k127_305086_18 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000001673 155.0
HKD1_k127_305086_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000013 142.0
HKD1_k127_305086_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 380.0
HKD1_k127_305086_20 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000729 139.0
HKD1_k127_305086_21 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000001312 135.0
HKD1_k127_305086_22 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000001251 122.0
HKD1_k127_305086_23 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000002506 125.0
HKD1_k127_305086_24 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000002764 110.0
HKD1_k127_305086_25 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000004519 99.0
HKD1_k127_305086_26 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000003397 75.0
HKD1_k127_305086_27 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000001561 64.0
HKD1_k127_305086_28 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000002574 64.0
HKD1_k127_305086_29 PFAM ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000116 61.0
HKD1_k127_305086_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 330.0
HKD1_k127_305086_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 285.0
HKD1_k127_305086_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001415 270.0
HKD1_k127_305086_6 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008375 269.0
HKD1_k127_305086_7 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000006676 226.0
HKD1_k127_305086_8 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000004302 210.0
HKD1_k127_305086_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001018 209.0
HKD1_k127_3055958_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 288.0
HKD1_k127_3055958_1 Tfp pilus assembly protein FimV - - - 0.0009112 51.0
HKD1_k127_3084050_0 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 485.0
HKD1_k127_3084050_1 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002609 262.0
HKD1_k127_3084050_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000001527 168.0
HKD1_k127_3084050_3 Protein of unknown function (DUF1298) - - - 0.0000000000000000000001066 105.0
HKD1_k127_3084050_4 Domain of Unknown Function (DUF748) - - - 0.000000000002153 82.0
HKD1_k127_3084050_5 Protein of unknown function, DUF481 - - - 0.0004627 52.0
HKD1_k127_308438_0 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 481.0
HKD1_k127_308438_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000001322 229.0
HKD1_k127_3091889_0 Peptidase dimerisation domain K13049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 521.0
HKD1_k127_3091889_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 428.0
HKD1_k127_3091889_10 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000008509 107.0
HKD1_k127_3091889_2 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 330.0
HKD1_k127_3091889_3 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 304.0
HKD1_k127_3091889_4 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000005778 216.0
HKD1_k127_3091889_5 Domain of unknown function (DUF4380) - - - 0.0000000000000000000000000000000000000000000000000754 191.0
HKD1_k127_3091889_6 Two component transcriptional regulator, LuxR family K14987 - - 0.00000000000000000000000000000000000000003755 160.0
HKD1_k127_3091889_7 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000001206 137.0
HKD1_k127_3091889_8 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000001594 115.0
HKD1_k127_3091889_9 HlyD family secretion protein K01993 - - 0.0000000000000000000000006995 109.0
HKD1_k127_3095741_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 399.0
HKD1_k127_3095741_1 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000006904 113.0
HKD1_k127_3104514_0 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 365.0
HKD1_k127_3110660_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002722 255.0
HKD1_k127_3110660_1 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000000001584 230.0
HKD1_k127_3110660_2 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000003624 214.0
HKD1_k127_3110660_3 Belongs to the glycosyl hydrolase 43 family K15921 - 3.2.1.55 0.0005888 46.0
HKD1_k127_3111378_0 RNA polymerase sigma factor containing a TPR repeat domain K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 563.0
HKD1_k127_3111378_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 540.0
HKD1_k127_3111378_2 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 439.0
HKD1_k127_3111378_3 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007914 373.0
HKD1_k127_3111378_4 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000005406 202.0
HKD1_k127_3111378_5 TIGRFAM autotransporter-associated beta strand repeat protein - - - 0.000000000000000000000000000000000000000000003397 183.0
HKD1_k127_3111378_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000000000000000000000000003382 154.0
HKD1_k127_3111378_7 YCII-related domain - - - 0.00000000000000000000000000000000001717 138.0
HKD1_k127_3111597_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 4.965e-198 643.0
HKD1_k127_3111597_1 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 482.0
HKD1_k127_3111597_10 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000002849 107.0
HKD1_k127_3111597_11 xylan catabolic process K03932 - - 0.00001064 60.0
HKD1_k127_3111597_12 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.00001226 51.0
HKD1_k127_3111597_2 Sodium/hydrogen exchanger family K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007488 445.0
HKD1_k127_3111597_3 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 338.0
HKD1_k127_3111597_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 314.0
HKD1_k127_3111597_5 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001076 241.0
HKD1_k127_3111597_6 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000004951 259.0
HKD1_k127_3111597_7 PFAM Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000002035 174.0
HKD1_k127_3111597_8 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000075 177.0
HKD1_k127_3111597_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001107 173.0
HKD1_k127_3128420_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.0 1461.0
HKD1_k127_3128420_1 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 420.0
HKD1_k127_3128420_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.000000000000000000000000000000000000000007489 158.0
HKD1_k127_3128420_3 Transcriptional regulator - - - 0.0000000000000000005202 90.0
HKD1_k127_3130352_0 Belongs to the glutaminase family K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 445.0
HKD1_k127_3130352_1 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000131 243.0
HKD1_k127_3130352_2 Pfam:DUF2305 - - - 0.00000000000000000000000000000000000000000000000000000000006228 226.0
HKD1_k127_3130352_3 PFAM CobQ CobB MinD ParA nucleotide binding domain - - - 0.0000000000000000000000000000000000000000000000005657 194.0
HKD1_k127_3132381_0 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 467.0
HKD1_k127_3132381_2 - - - - 0.000000000001648 76.0
HKD1_k127_3132381_3 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.000000001038 70.0
HKD1_k127_3132381_4 - - - - 0.000000018 66.0
HKD1_k127_3135114_0 choline dehydrogenase activity - - - 4.533e-222 713.0
HKD1_k127_3135114_1 gluconolactonase activity K01053 - 3.1.1.17 1.086e-212 680.0
HKD1_k127_3135114_10 Lytic murein transglycosylase K08309 - - 0.00000000000000000001068 101.0
HKD1_k127_3135114_2 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 548.0
HKD1_k127_3135114_3 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 407.0
HKD1_k127_3135114_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 365.0
HKD1_k127_3135114_5 Major intrinsic protein K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 310.0
HKD1_k127_3135114_6 PFAM ABC-1 domain protein K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003499 276.0
HKD1_k127_3135114_7 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000008503 202.0
HKD1_k127_3135114_8 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000000000000000000000000000000004712 180.0
HKD1_k127_3135114_9 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000000000000000000000000000008406 160.0
HKD1_k127_3143417_0 Methionine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 415.0
HKD1_k127_3143417_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 321.0
HKD1_k127_3143417_10 RDD family - - - 0.00000000000000000000001976 112.0
HKD1_k127_3143417_11 Protein of unknown function (DUF1329) - - - 0.0000000000000000006326 100.0
HKD1_k127_3143417_12 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000003361 83.0
HKD1_k127_3143417_13 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000008534 93.0
HKD1_k127_3143417_14 integral membrane protein - - - 0.0002365 52.0
HKD1_k127_3143417_15 - - - - 0.0002404 51.0
HKD1_k127_3143417_16 Domain of unknown function (DUF4350) - - - 0.0002812 53.0
HKD1_k127_3143417_2 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004284 287.0
HKD1_k127_3143417_3 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008545 265.0
HKD1_k127_3143417_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000008632 209.0
HKD1_k127_3143417_5 IMG reference gene - - - 0.000000000000000000000000000000000000000000009027 181.0
HKD1_k127_3143417_6 DoxX K15977 - - 0.00000000000000000000000000000000000000000004301 166.0
HKD1_k127_3143417_7 DUF218 domain - - - 0.000000000000000000000000000000001273 141.0
HKD1_k127_3143417_8 membrane - - - 0.00000000000000000000000000000005752 139.0
HKD1_k127_3143417_9 phosphohistidine phosphatase, SixA - - - 0.000000000000000000000000000187 127.0
HKD1_k127_3149834_0 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000001185 219.0
HKD1_k127_3149834_1 Bacterial Ig-like domain - - - 0.00000000001699 73.0
HKD1_k127_316220_0 phosphorelay signal transduction system K10941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 339.0
HKD1_k127_316220_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 305.0
HKD1_k127_316220_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000001259 194.0
HKD1_k127_316220_3 Histidine kinase - - - 0.0000000000000000000000002053 121.0
HKD1_k127_316220_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.000000000000002446 84.0
HKD1_k127_316220_5 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000002121 70.0
HKD1_k127_3163863_0 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 451.0
HKD1_k127_3163863_1 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005879 272.0
HKD1_k127_3163863_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000002532 192.0
HKD1_k127_3163863_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000001421 140.0
HKD1_k127_3163863_4 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000004667 102.0
HKD1_k127_3163863_5 Ion transport 2 domain protein - - - 0.00000000000004452 81.0
HKD1_k127_317065_0 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 460.0
HKD1_k127_317065_1 OB-fold nucleic acid binding domain K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 347.0
HKD1_k127_317065_2 Methyltransferase domain K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000007274 168.0
HKD1_k127_317065_3 - - - - 0.000000000000000000000001106 113.0
HKD1_k127_317065_4 Divergent polysaccharide deacetylase K09798 - - 0.0004075 52.0
HKD1_k127_3172341_0 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000001764 212.0
HKD1_k127_3172341_1 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000003706 95.0
HKD1_k127_3174526_0 Carbon starvation protein K06200 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 2.171e-283 885.0
HKD1_k127_3174526_1 C1q and tumor necrosis factor related protein 3 K01796 GO:0001561,GO:0003674,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0005782,GO:0005829,GO:0005886,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006694,GO:0006699,GO:0006720,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008111,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008300,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016853,GO:0016854,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0033540,GO:0034440,GO:0034613,GO:0042579,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046394,GO:0046395,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055114,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0072329,GO:0072330,GO:0072594,GO:0072662,GO:0072663,GO:1901360,GO:1901362,GO:1901575,GO:1901576,GO:1901615,GO:1901617 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 467.0
HKD1_k127_3174526_2 Alpha-methylacyl-CoA racemase K01796 - 5.1.99.4 0.0003982 46.0
HKD1_k127_3175126_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 540.0
HKD1_k127_3175126_1 PFAM ABC transporter related K02003 - - 0.0000000000000000000001866 97.0
HKD1_k127_3178801_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.761e-286 897.0
HKD1_k127_3178801_1 conserved protein UCP033924 - - - 0.0000000000000000000000000000000000000003581 154.0
HKD1_k127_3178801_2 L,D-transpeptidase catalytic domain - - - 0.0000000000002908 72.0
HKD1_k127_3182986_0 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 509.0
HKD1_k127_3182986_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 451.0
HKD1_k127_3182986_10 Uncharacterized conserved protein (DUF2267) - - - 0.0002404 51.0
HKD1_k127_3182986_2 geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 413.0
HKD1_k127_3182986_3 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000009969 186.0
HKD1_k127_3182986_4 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000002367 147.0
HKD1_k127_3182986_5 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000001848 130.0
HKD1_k127_3182986_6 COG COG1253 Hemolysins and related proteins containing CBS domains K03699 - - 0.00000000000000000000005398 102.0
HKD1_k127_3182986_7 CBS domain K04767 - - 0.00000000000000000000009994 106.0
HKD1_k127_3182986_8 Universal stress protein - - - 0.000000000000000000001959 106.0
HKD1_k127_3182986_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000003031 81.0
HKD1_k127_321058_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 540.0
HKD1_k127_321058_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 473.0
HKD1_k127_321058_10 Pterin binding enzyme K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000001271 219.0
HKD1_k127_321058_11 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00004,K00008,K05351,K08322 - 1.1.1.14,1.1.1.303,1.1.1.380,1.1.1.4,1.1.1.9 0.000000000000000000000000000000000000000000000000000000000001354 233.0
HKD1_k127_321058_12 Inositol monophosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000009079 214.0
HKD1_k127_321058_13 Bacterial signalling protein N terminal repeat - - - 0.0000000000000000000000000000000000000000176 175.0
HKD1_k127_321058_14 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000002307 144.0
HKD1_k127_321058_15 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K10697 - - 0.000000000000000000000000000003861 128.0
HKD1_k127_321058_16 COG0208 Ribonucleotide reductase, beta subunit - - - 0.000000000000000008314 94.0
HKD1_k127_321058_17 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000002297 83.0
HKD1_k127_321058_18 PFAM cyclase family protein - - - 0.000000001336 69.0
HKD1_k127_321058_19 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000002061 59.0
HKD1_k127_321058_2 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 456.0
HKD1_k127_321058_20 PhoQ Sensor - - - 0.0000003937 60.0
HKD1_k127_321058_3 Belongs to the aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 382.0
HKD1_k127_321058_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 351.0
HKD1_k127_321058_5 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 309.0
HKD1_k127_321058_6 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 314.0
HKD1_k127_321058_7 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001468 287.0
HKD1_k127_321058_8 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002083 263.0
HKD1_k127_321058_9 PFAM YkuD domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000001357 260.0
HKD1_k127_3217140_0 Acyclic terpene utilisation family protein AtuA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 555.0
HKD1_k127_3217140_1 COG1024 Enoyl-CoA hydratase carnithine racemase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000003209 214.0
HKD1_k127_3217140_2 PFAM Conserved nitrate reductase-associated protein (Nitr_red_assoc) - - - 0.000007319 55.0
HKD1_k127_3224968_0 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 1.088e-198 628.0
HKD1_k127_3224968_1 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 379.0
HKD1_k127_3232451_0 PFAM NAD-glutamate dehydrogenase K15371 - 1.4.1.2 1.139e-298 974.0
HKD1_k127_3232451_1 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 2.321e-204 644.0
HKD1_k127_3232451_10 Pkd domain containing protein - - - 0.0003766 55.0
HKD1_k127_3232451_11 Nudix N-terminal - - - 0.0003961 46.0
HKD1_k127_3232451_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 485.0
HKD1_k127_3232451_3 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 298.0
HKD1_k127_3232451_4 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000001462 248.0
HKD1_k127_3232451_5 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000001311 193.0
HKD1_k127_3232451_7 Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner K04659 GO:0000902,GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0001968,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0003674,GO:0005102,GO:0005178,GO:0005488,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005912,GO:0005924,GO:0005927,GO:0006928,GO:0006950,GO:0007155,GO:0007275,GO:0007399,GO:0007517,GO:0007610,GO:0008150,GO:0008201,GO:0008284,GO:0009653,GO:0009888,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0012505,GO:0014812,GO:0016043,GO:0016203,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0019220,GO:0019222,GO:0022008,GO:0022603,GO:0022607,GO:0022610,GO:0030030,GO:0030054,GO:0030055,GO:0030154,GO:0030182,GO:0030334,GO:0030335,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031594,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033554,GO:0033555,GO:0033627,GO:0034103,GO:0034976,GO:0035989,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042325,GO:0042327,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043236,GO:0043237,GO:0043933,GO:0044085,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045202,GO:0045765,GO:0045937,GO:0046872,GO:0048265,GO:0048266,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048584,GO:0048666,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050730,GO:0050731,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050896,GO:0050920,GO:0050921,GO:0051093,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051270,GO:0051272,GO:0051451,GO:0051674,GO:0051716,GO:0060255,GO:0060538,GO:0061061,GO:0061448,GO:0062023,GO:0065003,GO:0065007,GO:0070161,GO:0071603,GO:0071622,GO:0071624,GO:0071840,GO:0080090,GO:0090022,GO:0090023,GO:0090136,GO:0097367,GO:0098609,GO:0120036,GO:0120039,GO:1901342,GO:1901343,GO:1901681,GO:1902622,GO:1902624,GO:2000026,GO:2000145,GO:2000147,GO:2000181 - 0.000001343 60.0
HKD1_k127_3232451_8 - - - - 0.000001725 60.0
HKD1_k127_3232451_9 - - - - 0.00002054 57.0
HKD1_k127_3246693_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 6.92e-211 675.0
HKD1_k127_3246693_1 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 503.0
HKD1_k127_3246693_2 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000000000000000000001316 169.0
HKD1_k127_3246693_3 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000002288 165.0
HKD1_k127_3246693_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000009838 154.0
HKD1_k127_3246693_5 Belongs to the Fur family K09825 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2000374,GO:2001141 - 0.0000000000000000000007993 103.0
HKD1_k127_3246693_6 Mut7-C ubiquitin - - - 0.00000002458 59.0
HKD1_k127_325068_0 B12 binding domain K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 390.0
HKD1_k127_325068_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 346.0
HKD1_k127_325068_2 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000003925 229.0
HKD1_k127_3255373_0 AAA ATPase domain - - - 5.616e-239 779.0
HKD1_k127_3255373_1 PFAM NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 284.0
HKD1_k127_3260279_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 602.0
HKD1_k127_3260279_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000004914 211.0
HKD1_k127_3260279_3 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000001528 199.0
HKD1_k127_3260279_4 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000006626 197.0
HKD1_k127_3260279_5 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.000000000000000000000000000000000000000009528 174.0
HKD1_k127_3260279_6 Protein of unknown function (DUF2834) - - - 0.00000000000000000000000000000000003596 140.0
HKD1_k127_3260279_7 Methyltransferase domain - - - 0.0000000000000000000000000000001578 145.0
HKD1_k127_3260279_8 - - - - 0.0000000000000000000000000006609 127.0
HKD1_k127_3260279_9 thiolester hydrolase activity - - - 0.0000000004996 72.0
HKD1_k127_3274699_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 447.0
HKD1_k127_3274699_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 307.0
HKD1_k127_3274699_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000519 288.0
HKD1_k127_3274699_3 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000002793 99.0
HKD1_k127_3281026_0 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.0001385 54.0
HKD1_k127_328795_0 Isocitrate isopropylmalate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 359.0
HKD1_k127_328795_1 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 345.0
HKD1_k127_3320050_0 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006583 606.0
HKD1_k127_3320050_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 481.0
HKD1_k127_3320050_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000008787 251.0
HKD1_k127_3320050_3 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001178 243.0
HKD1_k127_3346166_0 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 466.0
HKD1_k127_3346166_1 PFAM AMP-dependent synthetase and ligase K00666,K18688 - 6.2.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 459.0
HKD1_k127_3346166_2 SnoaL-like domain - - - 0.00000000000000000000000001745 114.0
HKD1_k127_3354516_0 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000003737 262.0
HKD1_k127_3354516_1 alpha-2-macroglobulin domain protein K06894 - - 0.000000000000000000000000000000000000000000000001012 179.0
HKD1_k127_3388111_0 PFAM Conserved region in glutamate synthase K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 0.0 1043.0
HKD1_k127_339117_0 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 588.0
HKD1_k127_339117_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 349.0
HKD1_k127_339117_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000002104 102.0
HKD1_k127_339117_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000002768 83.0
HKD1_k127_339117_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000004776 72.0
HKD1_k127_339117_5 - - - - 0.00000001764 61.0
HKD1_k127_3395653_0 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 422.0
HKD1_k127_3406505_0 methylenetetrahydrofolate reductase (NAD(P)H) activity K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 364.0
HKD1_k127_3406505_1 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000009696 209.0
HKD1_k127_3406969_0 Iron permease FTR1 family K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000001091 255.0
HKD1_k127_3406969_1 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000002644 178.0
HKD1_k127_3406969_2 - - - - 0.000000000000000000000000000000000000000004846 160.0
HKD1_k127_3406969_3 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000001856 152.0
HKD1_k127_3406969_4 Universal stress protein family - - - 0.000000000004367 69.0
HKD1_k127_3406969_5 - - - - 0.000003341 55.0
HKD1_k127_340899_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 496.0
HKD1_k127_340899_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 338.0
HKD1_k127_340899_10 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000001082 220.0
HKD1_k127_340899_11 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000000000003326 169.0
HKD1_k127_340899_12 PFAM Peptidase M22, glycoprotease K14742 - - 0.000000000000000000000000000001416 130.0
HKD1_k127_340899_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 340.0
HKD1_k127_340899_3 SMART PDZ DHR GLGF domain protein K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 349.0
HKD1_k127_340899_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 314.0
HKD1_k127_340899_5 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 300.0
HKD1_k127_340899_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006771 284.0
HKD1_k127_340899_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000165 270.0
HKD1_k127_340899_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000003557 258.0
HKD1_k127_340899_9 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000002627 222.0
HKD1_k127_3430679_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000148 206.0
HKD1_k127_3430679_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000002717 156.0
HKD1_k127_3430679_2 PFAM Uncharacterised protein family UPF0150 - - - 0.000001696 50.0
HKD1_k127_3442839_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 479.0
HKD1_k127_3442839_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 383.0
HKD1_k127_3442839_10 - - - - 0.0000000000000000000004785 111.0
HKD1_k127_3442839_11 lipolytic protein G-D-S-L family - - - 0.0000000000000000000005184 112.0
HKD1_k127_3442839_12 Predicted membrane protein (DUF2231) - - - 0.00000000001378 71.0
HKD1_k127_3442839_13 - - - - 0.000000001013 68.0
HKD1_k127_3442839_14 Beta-L-arabinofuranosidase, GH127 - - - 0.000005303 57.0
HKD1_k127_3442839_15 VIT family - - - 0.0001715 53.0
HKD1_k127_3442839_2 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 356.0
HKD1_k127_3442839_3 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 347.0
HKD1_k127_3442839_4 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005332 271.0
HKD1_k127_3442839_5 Acyl-protein synthetase, LuxE K06046 - 6.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000127 254.0
HKD1_k127_3442839_6 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000734 205.0
HKD1_k127_3442839_7 - - - - 0.00000000000000000000000000000000000000000000000000002137 199.0
HKD1_k127_3442839_8 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000246 192.0
HKD1_k127_3442839_9 Acyl-CoA reductase (LuxC) - - - 0.0000000000000000000000000000000006852 151.0
HKD1_k127_3453439_0 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000075 227.0
HKD1_k127_3453439_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000001001 214.0
HKD1_k127_3453439_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000002755 202.0
HKD1_k127_3453439_3 CYTH - - - 0.00000000000000000000000007625 113.0
HKD1_k127_3485795_0 PFAM Type II secretion system protein E K02454 - - 7.444e-205 652.0
HKD1_k127_3485795_1 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 382.0
HKD1_k127_3485795_10 General secretion pathway protein I K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000188 58.0
HKD1_k127_3485795_11 - - - - 0.000000812 53.0
HKD1_k127_3485795_12 General secretion pathway protein K02459 - - 0.000006631 58.0
HKD1_k127_3485795_13 general secretion pathway protein K K02460 - - 0.0001507 54.0
HKD1_k127_3485795_2 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000579 263.0
HKD1_k127_3485795_3 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000002261 215.0
HKD1_k127_3485795_4 Domain of unknown function (DUF4215) - - - 0.000000000000000000000000000000000000000000007803 184.0
HKD1_k127_3485795_5 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000009125 158.0
HKD1_k127_3485795_6 Type IV pilus assembly protein PilM; K02461 - - 0.000000000000000000000004135 117.0
HKD1_k127_3485795_7 Type II secretion system (T2SS), protein M K02462 - - 0.00000000000001873 82.0
HKD1_k127_3485795_8 Prokaryotic N-terminal methylation motif K02457 - - 0.0000000000001871 80.0
HKD1_k127_3519295_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 7.128e-218 694.0
HKD1_k127_3519295_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 602.0
HKD1_k127_3519295_2 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 303.0
HKD1_k127_3519295_3 membrane - - - 0.0000000000000000000000000000000000000000000537 177.0
HKD1_k127_3519295_4 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000003819 174.0
HKD1_k127_3519295_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000798 96.0
HKD1_k127_3519295_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000006208 89.0
HKD1_k127_3519683_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 1.006e-205 651.0
HKD1_k127_3519683_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 406.0
HKD1_k127_3519683_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 304.0
HKD1_k127_3519683_3 chloride channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 304.0
HKD1_k127_3519683_4 Belongs to the MenA family. Type 1 subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000008233 240.0
HKD1_k127_3519683_5 COG1283 Na phosphate symporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000001007 250.0
HKD1_k127_3519683_7 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000001512 96.0
HKD1_k127_3519683_8 Outer membrane lipoprotein-sorting protein - - - 0.000000000000004485 86.0
HKD1_k127_3547981_0 Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000001221 222.0
HKD1_k127_3547981_1 LytTr DNA-binding domain K02477,K07705,K21696 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.000000000000000000000000000000000000000000000000000002852 198.0
HKD1_k127_3547981_2 Histidine kinase K02478 - 2.7.13.3 0.00000000000000000000000000000000000000000000000273 188.0
HKD1_k127_356607_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K10676 - 1.14.13.20 7.582e-221 735.0
HKD1_k127_356607_1 Amidohydrolase K22213 - 4.1.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 407.0
HKD1_k127_356607_2 synthetase K18688 - 6.2.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 412.0
HKD1_k127_356607_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000004743 206.0
HKD1_k127_356607_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000001514 102.0
HKD1_k127_356607_5 Domain of unknown function (DUF4136) - - - 0.00000000009961 74.0
HKD1_k127_3582203_0 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 343.0
HKD1_k127_3582203_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000013 271.0
HKD1_k127_3582203_2 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000000001054 193.0
HKD1_k127_3582203_3 Protein of unknown function (DUF3303) - - - 0.000000000000000000000000000002275 129.0
HKD1_k127_3592343_0 PFAM ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000001826 202.0
HKD1_k127_3592343_1 DNA polymerase III, delta' K02340 - 2.7.7.7 0.0000000000000000000000000000006745 138.0
HKD1_k127_3629167_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 604.0
HKD1_k127_3629167_1 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 362.0
HKD1_k127_3629167_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 349.0
HKD1_k127_3629167_3 Belongs to the TtcA family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 304.0
HKD1_k127_3629167_4 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001204 264.0
HKD1_k127_3629167_5 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000006179 243.0
HKD1_k127_3629167_6 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000008294 227.0
HKD1_k127_3629167_7 Transcriptional regulator K07726 - - 0.00000004106 64.0
HKD1_k127_3629167_8 thiamine diphosphate biosynthetic process K03154 - - 0.00000007741 57.0
HKD1_k127_364192_0 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001672 282.0
HKD1_k127_364192_1 Phycocyanin alpha phycocyanobilin lyase-like protein - - - 0.00000961 58.0
HKD1_k127_3655493_0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002148 278.0
HKD1_k127_3655493_1 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000002968 205.0
HKD1_k127_3655493_2 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein K03790 - 2.3.1.128 0.00000000000000000000000000000000165 137.0
HKD1_k127_3655493_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000488 130.0
HKD1_k127_3655493_4 MMPL family K07003 - - 0.00000000000000000000004993 116.0
HKD1_k127_3655493_5 Phosphopantetheine attachment site K02078 - - 0.000000000000000000211 92.0
HKD1_k127_3655493_7 Diacylglycerol kinase catalytic domain - - - 0.00000000005638 73.0
HKD1_k127_3655493_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000002158 67.0
HKD1_k127_3689000_0 Required for the activity of the bacterial periplasmic transport system of putrescine K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 466.0
HKD1_k127_3689000_1 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 426.0
HKD1_k127_3689000_2 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 381.0
HKD1_k127_3689000_3 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 324.0
HKD1_k127_3689000_4 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005231 285.0
HKD1_k127_3689000_5 adenosylmethionine-8-amino-7-oxononanoate transaminase activity K12256 - 2.6.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001364 275.0
HKD1_k127_3689000_6 - - - - 0.0000000000000000000000000000000000000000000000003594 187.0
HKD1_k127_3709651_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 372.0
HKD1_k127_3709651_1 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 338.0
HKD1_k127_3709651_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000186 193.0
HKD1_k127_3709651_3 protein conserved in bacteria K09990 - - 0.000000000000000000000000000000000000000000000003294 175.0
HKD1_k127_3709651_4 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0005154 49.0
HKD1_k127_3710269_0 Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002901 241.0
HKD1_k127_3710269_1 alpha beta - - - 0.000000000000000000000000000000000000000001708 170.0
HKD1_k127_3725020_0 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 573.0
HKD1_k127_3725020_1 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 383.0
HKD1_k127_3725020_2 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000161 182.0
HKD1_k127_3737117_0 ATPase associated with various cellular activities AAA_5 K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 364.0
HKD1_k127_3737117_1 von Willebrand factor (vWF) type A domain K02448 - - 0.000000000000002737 90.0
HKD1_k127_3737117_2 Tetratricopeptide repeat - - - 0.0001489 55.0
HKD1_k127_3737117_3 - - - - 0.0008517 51.0
HKD1_k127_3737934_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 6.624e-303 947.0
HKD1_k127_3737934_1 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 424.0
HKD1_k127_3737934_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 333.0
HKD1_k127_3737934_3 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000792 174.0
HKD1_k127_3737934_4 - - - - 0.00000000000000000000000000000006804 132.0
HKD1_k127_3737934_5 - - - - 0.0000000003284 71.0
HKD1_k127_375451_0 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 557.0
HKD1_k127_375451_1 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 435.0
HKD1_k127_375451_2 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000005956 273.0
HKD1_k127_375451_3 transferase activity, transferring hexosyl groups - - - 0.000000000000000000000000000000000000000000000000000003056 205.0
HKD1_k127_3755283_0 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K11384 - - 0.000000000000000000000000000000000000000000000000000000001661 207.0
HKD1_k127_3755283_1 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000006483 177.0
HKD1_k127_3759715_0 amine dehydrogenase activity K20276 - - 0.00000000000000000000000005275 123.0
HKD1_k127_3759715_1 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00003033 53.0
HKD1_k127_3771924_0 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 287.0
HKD1_k127_3771924_1 - - - - 0.00000000000000000000000000000000000000000000000000000001878 207.0
HKD1_k127_3771924_2 - - - - 0.000000000000000000009366 96.0
HKD1_k127_3780052_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18299 - - 0.0 1465.0
HKD1_k127_3780052_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 612.0
HKD1_k127_3780052_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 400.0
HKD1_k127_3780052_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009991 384.0
HKD1_k127_3780052_4 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000005579 180.0
HKD1_k127_3780052_5 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000004629 120.0
HKD1_k127_3780052_6 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000005704 75.0
HKD1_k127_3780052_7 Sodium/hydrogen exchanger family K03316 - - 0.0000000006298 59.0
HKD1_k127_378395_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 408.0
HKD1_k127_378395_1 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 393.0
HKD1_k127_378395_2 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 386.0
HKD1_k127_378395_3 MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 370.0
HKD1_k127_378395_4 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000002707 243.0
HKD1_k127_378395_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000002251 172.0
HKD1_k127_378395_6 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000001037 137.0
HKD1_k127_378395_7 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000003717 94.0
HKD1_k127_378395_8 DIE2/ALG10 family - - - 0.000000000000002441 88.0
HKD1_k127_378395_9 Pilus assembly protein, PilP K02665 - - 0.0000000002485 73.0
HKD1_k127_3798927_0 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 537.0
HKD1_k127_3798927_1 Rubrerythrin K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 488.0
HKD1_k127_3798927_2 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 421.0
HKD1_k127_3798927_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006209 265.0
HKD1_k127_3798927_4 Proto-chlorophyllide reductase 57 kD subunit - - - 0.000000000000000000000000000000000000000000000000000000000005174 219.0
HKD1_k127_3798927_5 Cytochrome c - - - 0.00000000000000000000000000000000000000000000009153 179.0
HKD1_k127_3798927_6 protein tyrosine kinase activity K03593 - - 0.00000000000000000000000000000000000008559 153.0
HKD1_k127_3798927_7 Cytochrome c - - - 0.0000000000000000000000000000005835 139.0
HKD1_k127_3798927_9 Cytochrome c K08738 - - 0.0000000000000805 81.0
HKD1_k127_3799174_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 2.352e-294 949.0
HKD1_k127_3799174_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003108 273.0
HKD1_k127_3799174_2 PFAM outer membrane efflux protein K15725 - - 0.00000000000000000000000000003564 128.0
HKD1_k127_3809773_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 456.0
HKD1_k127_3809773_1 Domain of unknown function (DUF309) K09763 - - 0.000000000000000000001657 103.0
HKD1_k127_3809773_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K01406 - 3.4.24.40 0.000000000009469 71.0
HKD1_k127_3843990_0 multidrug resistance K15549 GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015546,GO:0015893,GO:0015906,GO:0022857,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0042891,GO:0042895,GO:0042908,GO:0042910,GO:0045117,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072348,GO:1901474,GO:1901682,GO:1902599 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 329.0
HKD1_k127_3843990_1 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007823 303.0
HKD1_k127_3843990_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 287.0
HKD1_k127_3843990_3 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002417 267.0
HKD1_k127_3843990_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000002325 161.0
HKD1_k127_3843990_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain - - - 0.00000000000000000000000000000001946 134.0
HKD1_k127_3843990_6 Uncharacterised protein family - - - 0.00000000003807 70.0
HKD1_k127_3843990_7 Fusaric acid resistance protein family K15547 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015546,GO:0015893,GO:0015906,GO:0016020,GO:0022857,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0042891,GO:0042895,GO:0042908,GO:0042910,GO:0044464,GO:0045117,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:1901474,GO:1901682,GO:1902599 - 0.0000000002047 75.0
HKD1_k127_3891414_0 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 425.0
HKD1_k127_3891414_1 LysR substrate binding domain K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 295.0
HKD1_k127_3945820_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001601 269.0
HKD1_k127_3945820_1 protein conserved in bacteria K04750 - - 0.00000000000000000001782 99.0
HKD1_k127_3953022_0 Belongs to the long-chain O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 418.0
HKD1_k127_3953022_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 310.0
HKD1_k127_3953022_2 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002801 271.0
HKD1_k127_3953022_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000002828 211.0
HKD1_k127_3953022_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000001228 197.0
HKD1_k127_3953022_5 CRS1_YhbY K07574 - - 0.00000000000000000000000001748 113.0
HKD1_k127_3964117_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 449.0
HKD1_k127_3964117_1 acyl-CoA hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003858 261.0
HKD1_k127_3964117_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000003528 184.0
HKD1_k127_3975532_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000051 222.0
HKD1_k127_3975532_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000006326 196.0
HKD1_k127_3975532_2 mttA/Hcf106 family K03116,K03117 - - 0.000000000004664 71.0
HKD1_k127_4020044_0 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 309.0
HKD1_k127_4020044_1 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 287.0
HKD1_k127_4020044_2 Ion channel - - - 0.00000000000000000000000008004 118.0
HKD1_k127_4020044_3 membrane transporter protein K07090 - - 0.000000000004366 74.0
HKD1_k127_4044324_0 Belongs to the TPP enzyme family K04103 - 4.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 346.0
HKD1_k127_4053921_0 Putative zinc-finger K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000776 286.0
HKD1_k127_4053921_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000004166 144.0
HKD1_k127_4053921_2 Protein of unknown function (DUF2892) - - - 0.00000000001785 68.0
HKD1_k127_4053921_3 acyl-coA-binding protein - - - 0.000000001097 59.0
HKD1_k127_4062630_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 1.487e-238 741.0
HKD1_k127_4062630_1 PFAM ABC transporter K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 518.0
HKD1_k127_4062630_2 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 459.0
HKD1_k127_4062630_3 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000006983 186.0
HKD1_k127_4062630_4 - - - - 0.0000000000000000000000000000008954 128.0
HKD1_k127_4062630_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.00000000000000000000000002303 126.0
HKD1_k127_4062630_6 Glycosyl transferase family 2 - - - 0.000002453 53.0
HKD1_k127_4074197_0 His Kinase A (phosphoacceptor) domain K11711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000001514 217.0
HKD1_k127_4074197_1 Pfam Amidohydrolase - - - 0.000000000000000000000000000001057 128.0
HKD1_k127_4074197_2 GDSL-like Lipase/Acylhydrolase - - - 0.000000000003267 78.0
HKD1_k127_4081225_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000405 298.0
HKD1_k127_4081225_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.0000000000000000000000000000000001276 140.0
HKD1_k127_4084130_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 587.0
HKD1_k127_4084130_1 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 456.0
HKD1_k127_4084130_2 PFAM General substrate transporter K03761,K03762 - - 0.00006763 47.0
HKD1_k127_4096388_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000003613 139.0
HKD1_k127_4096388_1 Protein of unknown function (DUF1501) - - - 0.0000000000000004647 87.0
HKD1_k127_4101561_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.878e-266 846.0
HKD1_k127_4101561_1 YicC domain protein - - - 0.00000000000000000000000000000000000000000000000000001067 200.0
HKD1_k127_4101561_2 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000001744 167.0
HKD1_k127_4101561_3 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000001499 144.0
HKD1_k127_410261_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 371.0
HKD1_k127_410261_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002617 302.0
HKD1_k127_410261_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001265 258.0
HKD1_k127_410261_3 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000002781 175.0
HKD1_k127_410261_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000009086 115.0
HKD1_k127_410261_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000009981 95.0
HKD1_k127_410261_6 Thrombospondin type 3 repeat - - - 0.00001477 60.0
HKD1_k127_4113324_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 405.0
HKD1_k127_4113324_1 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001856 272.0
HKD1_k127_4113324_2 Multi-sensor signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000101 246.0
HKD1_k127_4113324_3 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000001017 166.0
HKD1_k127_4113324_5 Histidine kinase - - - 0.00000002477 67.0
HKD1_k127_4113470_0 Sulfatase - - - 6.511e-237 764.0
HKD1_k127_4113470_1 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003957 286.0
HKD1_k127_4113470_2 ABC transporter substrate-binding protein K01989 - - 0.0001596 53.0
HKD1_k127_4116273_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 568.0
HKD1_k127_4116273_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 563.0
HKD1_k127_4116273_10 Membrane proteins related to metalloendopeptidases K06194 - - 0.000000000000000000000000000000000003859 145.0
HKD1_k127_4116273_11 Member of the two-component regulatory system AtoS AtoC. In the presence of acetoacetate, AtoS AtoC stimulates the expression of the atoDAEB operon, leading to short chain fatty acid catabolism and activation of the poly-(R)-3-hydroxybutyrate (cPHB) biosynthetic pathway. Also induces the operon in response to spermidine. Involved in the regulation of motility and chemotaxis, via transcriptional induction of the flagellar regulon. AtoS is a membrane-associated kinase that phosphorylates and activates AtoC in response to environmental signals K07710 GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000000000000000004176 149.0
HKD1_k127_4116273_12 peptidyl-tyrosine sulfation - - - 0.00000000000000000007995 99.0
HKD1_k127_4116273_13 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.00000000000000001409 91.0
HKD1_k127_4116273_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 401.0
HKD1_k127_4116273_3 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 303.0
HKD1_k127_4116273_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 297.0
HKD1_k127_4116273_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009 287.0
HKD1_k127_4116273_6 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002235 266.0
HKD1_k127_4116273_7 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000821 216.0
HKD1_k127_4116273_8 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000005219 220.0
HKD1_k127_4116273_9 Serine aminopeptidase, S33 K09023 - - 0.00000000000000000000000000000000000000214 163.0
HKD1_k127_4117118_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 410.0
HKD1_k127_4117118_1 FAD linked oxidases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 412.0
HKD1_k127_4126724_0 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 375.0
HKD1_k127_4128279_0 Acetyl-CoA carboxylase, central region - - - 0.0 1027.0
HKD1_k127_4128279_1 short chain dehydrogenase K00218 - 1.3.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 294.0
HKD1_k127_4132449_0 Integrase core domain - - - 2.715e-194 619.0
HKD1_k127_4132449_1 Bacterial dnaA protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 338.0
HKD1_k127_4142818_0 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 364.0
HKD1_k127_4142818_1 Dystroglycan-type cadherin-like domains. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004728 274.0
HKD1_k127_4142818_2 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.000000000001226 78.0
HKD1_k127_4144728_0 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 415.0
HKD1_k127_4144728_1 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000003135 103.0
HKD1_k127_4144728_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000004912 80.0
HKD1_k127_4145700_0 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 389.0
HKD1_k127_4145700_1 MMPL family K07003 - - 0.00000000000000000000000001909 120.0
HKD1_k127_4146455_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.005e-276 870.0
HKD1_k127_4146455_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.272e-215 690.0
HKD1_k127_4146455_10 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000977 111.0
HKD1_k127_4146455_11 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000001325 85.0
HKD1_k127_4146455_12 PFAM S-layer domain protein - - - 0.000000001372 65.0
HKD1_k127_4146455_13 Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.0000008711 60.0
HKD1_k127_4146455_2 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.778e-203 659.0
HKD1_k127_4146455_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 558.0
HKD1_k127_4146455_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 433.0
HKD1_k127_4146455_5 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000001669 192.0
HKD1_k127_4146455_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000009613 151.0
HKD1_k127_4146455_7 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000003598 125.0
HKD1_k127_4146455_8 regulatory protein, MerR - - - 0.0000000000000000000000000125 118.0
HKD1_k127_4146455_9 - - - - 0.0000000000000000000005428 105.0
HKD1_k127_4151111_0 elongation factor Tu domain 2 protein K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 331.0
HKD1_k127_4151111_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 292.0
HKD1_k127_4151111_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000877 218.0
HKD1_k127_4165099_0 PFAM TonB-dependent receptor, beta-barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005916 304.0
HKD1_k127_4165099_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000002456 188.0
HKD1_k127_4174802_0 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 292.0
HKD1_k127_4174802_1 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009424 297.0
HKD1_k127_4189395_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 452.0
HKD1_k127_4189395_1 HAMP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002392 293.0
HKD1_k127_4196425_0 COG0464 ATPases of the AAA class - - - 8.061e-195 622.0
HKD1_k127_4196425_1 Cytochrome P450 K21119 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0020037,GO:0030312,GO:0044464,GO:0046906,GO:0048037,GO:0071944,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 449.0
HKD1_k127_4196425_10 arylsulfatase A - - - 0.0000000000000000000007077 103.0
HKD1_k127_4196425_11 response regulator K07668,K07775 - - 0.0000000000000006759 85.0
HKD1_k127_4196425_12 Pfam:DUF385 - - - 0.0000005975 61.0
HKD1_k127_4196425_13 Acetyltransferase (GNAT) domain - - - 0.0007497 46.0
HKD1_k127_4196425_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 359.0
HKD1_k127_4196425_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000117 285.0
HKD1_k127_4196425_4 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003556 278.0
HKD1_k127_4196425_5 DHH family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007402 265.0
HKD1_k127_4196425_6 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000514 217.0
HKD1_k127_4196425_7 MaoC like domain K14449 GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.0000000000000000000000000000000000000000000000001638 190.0
HKD1_k127_4196425_8 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000001231 107.0
HKD1_k127_4196425_9 40-residue YVTN family beta-propeller - - - 0.0000000000000000000001963 106.0
HKD1_k127_4198913_0 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 328.0
HKD1_k127_4199815_0 Belongs to the long-chain O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 400.0
HKD1_k127_4199815_1 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000007162 179.0
HKD1_k127_4199815_2 Acetyl propionyl-CoA carboxylase, alpha subunit - - - 0.0000000000000000000000432 109.0
HKD1_k127_420575_0 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 384.0
HKD1_k127_420575_1 PFAM WD domain, G-beta repeat - - - 0.0000000000000000000000000000000001302 154.0
HKD1_k127_420575_2 cheY-homologous receiver domain K02485 - - 0.00000000000000000004431 94.0
HKD1_k127_4206988_0 ferredoxin-NADP+ reductase activity K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 412.0
HKD1_k127_4206988_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 336.0
HKD1_k127_4206988_2 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001247 270.0
HKD1_k127_4206988_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000005472 188.0
HKD1_k127_4206988_4 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000006317 96.0
HKD1_k127_4213314_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002738 248.0
HKD1_k127_4213314_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000001692 138.0
HKD1_k127_4213314_2 Flavin containing amine oxidoreductase - - - 0.0000005085 64.0
HKD1_k127_4222245_0 peptidase activity, acting on L-amino acid peptides K01337,K01400,K20276 - 3.4.21.50,3.4.24.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 336.0
HKD1_k127_4222245_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000001953 242.0
HKD1_k127_4222245_2 HpcH/HpaI aldolase/citrate lyase family K01644,K18292 - 4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000007339 222.0
HKD1_k127_4226105_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 577.0
HKD1_k127_4226105_1 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006903 277.0
HKD1_k127_4226105_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009441 291.0
HKD1_k127_4226105_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000002688 270.0
HKD1_k127_4226105_4 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000003464 232.0
HKD1_k127_4226105_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000002917 181.0
HKD1_k127_4228592_0 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007871 255.0
HKD1_k127_424096_0 SNF2 family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 478.0
HKD1_k127_424096_1 alpha beta - - - 0.00000000000000000004102 106.0
HKD1_k127_424096_2 - - - - 0.000000000003304 75.0
HKD1_k127_4243910_0 gluconolactonase K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 353.0
HKD1_k127_4244227_0 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 342.0
HKD1_k127_4244227_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 338.0
HKD1_k127_4244227_2 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000002398 266.0
HKD1_k127_4244645_0 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 520.0
HKD1_k127_4244645_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 312.0
HKD1_k127_4244645_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 299.0
HKD1_k127_4244645_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000009808 258.0
HKD1_k127_4244645_4 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000003042 229.0
HKD1_k127_4244645_5 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000173 190.0
HKD1_k127_4244645_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000414 61.0
HKD1_k127_4244645_7 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0002737 51.0
HKD1_k127_4247774_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 315.0
HKD1_k127_4247774_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 296.0
HKD1_k127_4247774_2 peptidase activity, acting on L-amino acid peptides K20276 - - 0.00000000005888 72.0
HKD1_k127_4264315_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 546.0
HKD1_k127_4264315_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 332.0
HKD1_k127_4264315_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000003223 243.0
HKD1_k127_4264315_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000266 219.0
HKD1_k127_4264315_4 COGs COG2133 Glucose sorbosone dehydrogenase - - - 0.000000000000000001122 100.0
HKD1_k127_4272935_0 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 360.0
HKD1_k127_4272935_1 PFAM Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000001391 235.0
HKD1_k127_4272935_2 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000000000000000000000000005025 224.0
HKD1_k127_4272935_3 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.000000000000006509 76.0
HKD1_k127_4272935_4 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine K18912 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.14.99.50 0.00000001979 65.0
HKD1_k127_4288833_0 COG2355 Zn-dependent dipeptidase microsomal dipeptidase homolog - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 507.0
HKD1_k127_4288833_1 lipid-transfer protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 350.0
HKD1_k127_4288833_2 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000001546 245.0
HKD1_k127_4288833_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002523 243.0
HKD1_k127_4288833_4 Pfam Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000001166 218.0
HKD1_k127_4288833_5 - K03561,K12287 - - 0.000000000000000000000000000000000000000000002289 191.0
HKD1_k127_4288833_6 TIGRFAM prepilin-type N-terminal cleavage methylation domain - - - 0.0000000001387 68.0
HKD1_k127_4288833_7 Dienelactone hydrolase family - - - 0.00001341 57.0
HKD1_k127_4289813_0 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 294.0
HKD1_k127_4289813_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003732 241.0
HKD1_k127_4289813_2 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000001492 226.0
HKD1_k127_4299427_0 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000001191 177.0
HKD1_k127_4299427_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000002718 169.0
HKD1_k127_4300242_0 PFAM gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008455 539.0
HKD1_k127_4300242_1 cytochrome p450 K16046 - 1.14.13.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008801 415.0
HKD1_k127_4300242_10 Flavin reductase like domain - - - 0.000000000000000000000002348 108.0
HKD1_k127_4300242_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 403.0
HKD1_k127_4300242_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 314.0
HKD1_k127_4300242_4 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001164 273.0
HKD1_k127_4300242_5 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000002994 240.0
HKD1_k127_4300242_6 Subtilase family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000006799 240.0
HKD1_k127_4300242_7 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000005335 201.0
HKD1_k127_4300242_8 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000004026 174.0
HKD1_k127_4300242_9 SMART HNH nuclease K07451 - - 0.0000000000000000000000000000003708 125.0
HKD1_k127_4326182_0 PFAM AAA ATPase central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 489.0
HKD1_k127_4326182_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 400.0
HKD1_k127_4326182_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 354.0
HKD1_k127_4326182_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 367.0
HKD1_k127_4326182_4 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 321.0
HKD1_k127_4326182_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000002026 266.0
HKD1_k127_4326182_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000004592 267.0
HKD1_k127_4326182_7 Semialdehyde dehydrogenase, dimerisation domain K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000002847 237.0
HKD1_k127_4326182_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000001004 222.0
HKD1_k127_4326182_9 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0004211 54.0
HKD1_k127_4335838_0 Pyridoxal-dependent decarboxylase conserved domain K01580,K01634 - 4.1.1.15,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 557.0
HKD1_k127_4335838_1 PFAM glycoside hydrolase family 29 (alpha-L-fucosidase) K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 377.0
HKD1_k127_4335838_2 SMP-30/Gluconolaconase/LRE-like region K01045 - 3.1.1.2,3.1.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000635 267.0
HKD1_k127_4335838_3 Histidine kinase - - - 0.00000000000000000000000000000000000001097 162.0
HKD1_k127_4342241_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.825e-219 694.0
HKD1_k127_4342241_1 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000005548 89.0
HKD1_k127_4362322_0 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 570.0
HKD1_k127_4362322_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 403.0
HKD1_k127_4362322_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15785 - 2.6.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 368.0
HKD1_k127_4362322_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000000001579 203.0
HKD1_k127_4362322_5 Alpha/beta hydrolase family - - - 0.0001646 54.0
HKD1_k127_4377256_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 413.0
HKD1_k127_4377256_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003223 243.0
HKD1_k127_4377256_2 Thiol disulfide interchange protein dsbA - - - 0.0001018 47.0
HKD1_k127_4377296_0 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 516.0
HKD1_k127_4377296_1 COG0695 glutaredoxin and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 306.0
HKD1_k127_4377296_2 Domain of unknown function (DUF4336) - - - 0.000000000000000000000000000000000000000000000000000000000004801 215.0
HKD1_k127_4377296_3 Tyrosine phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000004996 165.0
HKD1_k127_4392189_0 HD superfamily K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 502.0
HKD1_k127_4392189_1 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000002395 193.0
HKD1_k127_4392189_2 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000000000000000000000000000000000000000000005709 190.0
HKD1_k127_4399243_0 Aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 501.0
HKD1_k127_4399243_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000005967 185.0
HKD1_k127_4399243_2 alpha-ribazole phosphatase activity K02226,K15634,K15640 - 3.1.3.73,5.4.2.12 0.0000000000000000000000000000008114 139.0
HKD1_k127_4406468_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009678 471.0
HKD1_k127_4406468_1 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 404.0
HKD1_k127_4406468_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000001623 162.0
HKD1_k127_4406468_3 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.000000000000000000000388 105.0
HKD1_k127_4410511_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 7.959e-226 710.0
HKD1_k127_4410511_1 Pfam:DUF1446 - - - 5.805e-217 687.0
HKD1_k127_4410511_2 Biotin carboxylase C-terminal domain K13777 - 6.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 567.0
HKD1_k127_4410511_3 FAD dependent oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 529.0
HKD1_k127_4410511_4 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 503.0
HKD1_k127_4410511_5 synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 356.0
HKD1_k127_4410511_6 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 319.0
HKD1_k127_4410511_7 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000002628 214.0
HKD1_k127_4410511_8 cobalamin binding K22491 - - 0.00000000000000000000000000005739 123.0
HKD1_k127_4418087_0 4Fe-4S dicluster domain K00184 - - 0.0 1120.0
HKD1_k127_4418087_1 Polysulphide reductase, NrfD K00185 - - 4.472e-210 669.0
HKD1_k127_4418087_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 538.0
HKD1_k127_4418087_3 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 389.0
HKD1_k127_4418087_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 347.0
HKD1_k127_4418087_5 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005095 277.0
HKD1_k127_4418087_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000005118 237.0
HKD1_k127_4418087_7 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000002515 219.0
HKD1_k127_4418087_8 - - - - 0.00000004532 66.0
HKD1_k127_4425012_0 SOS response associated peptidase (SRAP) - - - 0.0000000000000000000000000000000000000000000000000000000000005481 229.0
HKD1_k127_4425012_1 drug transmembrane transporter activity K03327 - - 0.000000000000000000000000000000000000000000000009345 189.0
HKD1_k127_4425012_2 PFAM TPR repeat-containing protein - - - 0.0000000000000006905 92.0
HKD1_k127_4425012_3 antibiotic catabolic process - - - 0.0000828 54.0
HKD1_k127_4450366_0 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 289.0
HKD1_k127_4450366_1 of the RND superfamily K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009117 302.0
HKD1_k127_4450366_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000187 90.0
HKD1_k127_4450366_3 Haem-NO-binding - - - 0.0005155 46.0
HKD1_k127_4454684_0 PFAM NAD dependent epimerase dehydratase family K12454 - 5.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 486.0
HKD1_k127_4454684_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 447.0
HKD1_k127_4454684_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000007044 162.0
HKD1_k127_4454684_3 Transferase hexapeptide repeat - - - 0.0000000000000000000003585 113.0
HKD1_k127_4454684_4 Tetratricopeptide repeat - - - 0.00009981 49.0
HKD1_k127_4467941_0 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 372.0
HKD1_k127_4467941_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000004856 211.0
HKD1_k127_4467941_2 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000002704 203.0
HKD1_k127_4473864_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 453.0
HKD1_k127_4473864_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 361.0
HKD1_k127_4473864_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000911 283.0
HKD1_k127_4473864_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000002721 229.0
HKD1_k127_4473864_4 MaoC like domain - - - 0.0000000000000000000000000000000000000000000003112 183.0
HKD1_k127_4473864_5 SnoaL-like domain - - - 0.0000000000000000000000007973 113.0
HKD1_k127_4473864_6 - - - - 0.000000000000000000008188 100.0
HKD1_k127_4476988_0 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 362.0
HKD1_k127_4476988_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000001372 224.0
HKD1_k127_4476988_2 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000005224 139.0
HKD1_k127_4476988_3 lipid-transfer protein - - - 0.000000000000000000000000000002928 123.0
HKD1_k127_4486113_0 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 346.0
HKD1_k127_4486113_1 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000001902 245.0
HKD1_k127_4496577_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 586.0
HKD1_k127_4496577_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 527.0
HKD1_k127_4496577_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 364.0
HKD1_k127_4496577_3 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 300.0
HKD1_k127_4496577_4 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009951 277.0
HKD1_k127_4496577_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002751 305.0
HKD1_k127_4496577_6 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000007571 183.0
HKD1_k127_4496577_7 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000001006 119.0
HKD1_k127_4496577_8 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00006319 49.0
HKD1_k127_4518887_0 Dehydrogenase E1 component K00164 - 1.2.4.2 1.225e-286 907.0
HKD1_k127_4518887_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000004299 104.0
HKD1_k127_4518887_2 transcriptional regulator, Rrf2 family - - - 0.00000000000000000004184 96.0
HKD1_k127_4533312_0 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 505.0
HKD1_k127_4533312_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001832 253.0
HKD1_k127_4533312_2 MlaC protein K07323 - - 0.000000000000000000000000000000000000005067 154.0
HKD1_k127_4533312_3 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000004693 153.0
HKD1_k127_4533312_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000005426 106.0
HKD1_k127_4533312_5 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.00000003488 55.0
HKD1_k127_4533312_6 - - - - 0.00002366 51.0
HKD1_k127_4548752_0 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 344.0
HKD1_k127_4548752_1 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007639 284.0
HKD1_k127_4548752_2 tRNA m6t6A37 methyltransferase activity K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000004496 206.0
HKD1_k127_4548752_3 collagen metabolic process - - - 0.000000000000000000000000000000000000000000000000003028 193.0
HKD1_k127_4548752_4 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000004603 147.0
HKD1_k127_4548752_5 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000002164 92.0
HKD1_k127_4575474_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 427.0
HKD1_k127_4575474_1 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000008126 164.0
HKD1_k127_4575474_2 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000004063 147.0
HKD1_k127_4575474_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000002676 131.0
HKD1_k127_4609616_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 400.0
HKD1_k127_4609616_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 314.0
HKD1_k127_4609616_2 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006818 229.0
HKD1_k127_4609616_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001536 231.0
HKD1_k127_4609616_4 PFAM MAPEG family - - - 0.000000000000000000000000000000000000007434 154.0
HKD1_k127_4611651_0 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 464.0
HKD1_k127_4611651_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 366.0
HKD1_k127_4611651_2 YsiA-like protein, C-terminal region - - - 0.0000000000000002757 87.0
HKD1_k127_4611651_3 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000002942 87.0
HKD1_k127_4637972_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.748e-295 931.0
HKD1_k127_4637972_1 Alpha beta hydrolase K01563 - 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 446.0
HKD1_k127_4637972_10 - - - - 0.00000000000000000000000000001326 128.0
HKD1_k127_4637972_11 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000001268 120.0
HKD1_k127_4637972_12 SnoaL-like domain - - - 0.0000000000000000000002214 103.0
HKD1_k127_4637972_2 PFAM PhoH family protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 411.0
HKD1_k127_4637972_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 320.0
HKD1_k127_4637972_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
HKD1_k127_4637972_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001274 265.0
HKD1_k127_4637972_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002128 278.0
HKD1_k127_4637972_7 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001158 236.0
HKD1_k127_4637972_8 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000001463 194.0
HKD1_k127_4637972_9 - - - - 0.000000000000000000000000000000000000006632 162.0
HKD1_k127_4659713_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 9.501e-234 750.0
HKD1_k127_4659713_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 2.558e-215 701.0
HKD1_k127_4659713_2 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 401.0
HKD1_k127_4659713_3 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001131 281.0
HKD1_k127_4659713_4 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000666 267.0
HKD1_k127_4659713_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001548 242.0
HKD1_k127_4659713_6 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000257 224.0
HKD1_k127_4659713_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000005107 226.0
HKD1_k127_4659713_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000001348 169.0
HKD1_k127_4683037_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 420.0
HKD1_k127_4683037_1 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000006518 269.0
HKD1_k127_4683037_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002934 255.0
HKD1_k127_4683037_3 COG0208 Ribonucleotide reductase, beta subunit - - - 0.0000000000000000000000000000000000188 143.0
HKD1_k127_4683037_4 alpha beta - - - 0.000000000000000000000005363 115.0
HKD1_k127_4683037_5 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000001866 97.0
HKD1_k127_4693898_0 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000000000000000000000000000000000000000000006333 262.0
HKD1_k127_4693898_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000007044 181.0
HKD1_k127_4693898_2 Thioredoxin-like - - - 0.00000000000000000000000000000000000001876 160.0
HKD1_k127_4693898_3 protein conserved in bacteria K09800 - - 0.0000001444 65.0
HKD1_k127_4711642_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 494.0
HKD1_k127_4711642_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 373.0
HKD1_k127_4711642_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 368.0
HKD1_k127_4711642_3 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000001914 103.0
HKD1_k127_4716376_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 537.0
HKD1_k127_4716376_1 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 317.0
HKD1_k127_4716376_2 XdhC and CoxI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001005 288.0
HKD1_k127_4716376_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000001148 186.0
HKD1_k127_4716376_4 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000000000000000002209 156.0
HKD1_k127_4716376_5 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000003938 136.0
HKD1_k127_4716376_6 exo-alpha-(2->6)-sialidase activity - - - 0.0000001301 65.0
HKD1_k127_4716376_7 NHL repeat containing protein - - - 0.00001622 55.0
HKD1_k127_471755_0 spore germination K16928 - - 0.0000000000000000000000000000000000000000000000000000009588 201.0
HKD1_k127_471755_1 PFAM ABC transporter related K16786,K16787 - - 0.00000000000000000000000000000000000000000000000003011 207.0
HKD1_k127_471755_2 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000004956 194.0
HKD1_k127_471755_3 3-hydroxyacyl-CoA dehydrogenase - - - 0.00000004598 67.0
HKD1_k127_47176_0 AMP-binding enzyme C-terminal domain K00666,K01897,K18660 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 473.0
HKD1_k127_47176_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 420.0
HKD1_k127_47176_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000002181 216.0
HKD1_k127_4721030_0 PhoQ Sensor - - - 1.566e-211 675.0
HKD1_k127_4721030_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 294.0
HKD1_k127_4726929_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 382.0
HKD1_k127_4726929_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000002243 140.0
HKD1_k127_4726929_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000001029 108.0
HKD1_k127_4730677_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 392.0
HKD1_k127_4730677_1 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 342.0
HKD1_k127_4746218_0 Sulfatase - - - 5.373e-259 821.0
HKD1_k127_4765345_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 394.0
HKD1_k127_4765345_1 Glycosyltransferase group 2 family protein K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002499 282.0
HKD1_k127_4765345_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000005605 181.0
HKD1_k127_4765345_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00006023 57.0
HKD1_k127_4765345_4 NHL repeat K00504 - 1.14.17.3 0.0002385 55.0
HKD1_k127_4768459_0 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 344.0
HKD1_k127_4768459_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 303.0
HKD1_k127_4768459_2 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000001102 122.0
HKD1_k127_4768459_3 aldo keto reductase K05882 - 1.1.1.91 0.000000000000000009972 85.0
HKD1_k127_4768459_4 outer membrane autotransporter barrel domain - - - 0.000000000000616 81.0
HKD1_k127_4775285_0 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000000000000000000000007967 114.0
HKD1_k127_4775285_1 Bile acid sodium symporter - - - 0.00000001116 60.0
HKD1_k127_4777121_0 synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 403.0
HKD1_k127_4777121_1 epimerase dehydratase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 362.0
HKD1_k127_4777121_2 Pyridoxamine 5'-phosphate - - - 0.000000000000000000000000000000000000004694 152.0
HKD1_k127_4777121_3 - - - - 0.00000000000000000000000000000000004014 150.0
HKD1_k127_4777121_4 transmembrane transporter activity - - - 0.000000000000000000000000000005137 134.0
HKD1_k127_4777121_5 cobalamin binding K22491 - - 0.00000000000000000002085 98.0
HKD1_k127_4777121_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000001271 64.0
HKD1_k127_4792876_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 441.0
HKD1_k127_4792876_1 ArsC family - - - 0.0000000000000000000000000000000006751 135.0
HKD1_k127_4792876_2 - - - - 0.00000000000000000000000000001544 128.0
HKD1_k127_4792876_4 Type III secretion system lipoprotein chaperone (YscW) - - - 0.00000000000003214 82.0
HKD1_k127_4792876_5 Belongs to the peptidase S8 family - - - 0.0000002704 62.0
HKD1_k127_481102_0 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000007689 154.0
HKD1_k127_481102_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000005135 164.0
HKD1_k127_481102_2 GAF domain - - - 0.000000000000000000007772 108.0
HKD1_k127_481102_3 Domain of unknown function (DUF1772) - - - 0.000000001132 70.0
HKD1_k127_4849361_0 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 365.0
HKD1_k127_4849361_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00007138 47.0
HKD1_k127_4873378_0 Clostripain family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 508.0
HKD1_k127_4873378_1 Inner membrane protein involved in colicin E2 resistance K06143 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 366.0
HKD1_k127_4873378_2 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001307 246.0
HKD1_k127_4873378_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001823 251.0
HKD1_k127_4873378_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005869 256.0
HKD1_k127_4873378_5 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008122 236.0
HKD1_k127_4873378_6 MAPEG family - - - 0.00000000000000000000003446 104.0
HKD1_k127_4873378_7 heptosyltransferase - - - 0.00000000000000002524 94.0
HKD1_k127_4874923_0 PFAM Cytochrome c oxidase caa3-type, assembly factor CtaG-related - - - 2.458e-228 728.0
HKD1_k127_4874923_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 336.0
HKD1_k127_4874923_2 PFAM phospholipase Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 304.0
HKD1_k127_4874923_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000004684 195.0
HKD1_k127_4874923_5 - - - - 0.00000000000000000000001569 118.0
HKD1_k127_4874923_6 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000495 103.0
HKD1_k127_4874923_7 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000001073 91.0
HKD1_k127_4908625_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 578.0
HKD1_k127_4908625_1 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000123 254.0
HKD1_k127_491755_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 520.0
HKD1_k127_491755_1 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 317.0
HKD1_k127_491755_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000002562 252.0
HKD1_k127_491755_3 'Cold-shock' DNA-binding domain K03704 - - 0.00000000001362 70.0
HKD1_k127_4922491_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 5.886e-303 945.0
HKD1_k127_4922491_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 295.0
HKD1_k127_4922491_3 Transcriptional regulator - - - 0.000000000000000000000000000007641 127.0
HKD1_k127_4922491_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000001122 105.0
HKD1_k127_4926289_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 509.0
HKD1_k127_4926289_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 467.0
HKD1_k127_4926289_10 PFAM ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000006018 115.0
HKD1_k127_4926289_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 370.0
HKD1_k127_4926289_3 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 339.0
HKD1_k127_4926289_4 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 290.0
HKD1_k127_4926289_5 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 299.0
HKD1_k127_4926289_6 Protein of unknown function (DUF1348) K09958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 282.0
HKD1_k127_4926289_7 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002373 262.0
HKD1_k127_4926289_8 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002721 265.0
HKD1_k127_4926289_9 iron--sulfur cluster insertion protein erpA K13628,K15724 - - 0.0000000000000000000000000000004236 124.0
HKD1_k127_4939802_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 353.0
HKD1_k127_4939802_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000001413 274.0
HKD1_k127_4939802_2 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000006029 250.0
HKD1_k127_4939802_3 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000005134 147.0
HKD1_k127_4939802_4 regulator of chromosome condensation, RCC1 - - - 0.00000000000005893 87.0
HKD1_k127_4947911_0 pyruvate dehydrogenase (acetyl-transferring) activity K00163 - 1.2.4.1 0.0 1155.0
HKD1_k127_4947911_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000003889 211.0
HKD1_k127_4947911_2 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000005864 91.0
HKD1_k127_4947911_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000005376 74.0
HKD1_k127_4962247_0 Methyltransferase small domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 439.0
HKD1_k127_4962247_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005328 282.0
HKD1_k127_4962247_2 PAS domain - - - 0.00000000000000000000000000000000002562 138.0
HKD1_k127_4962247_3 Domain of unknown function (DUF4082) - - - 0.000000000000000000002938 102.0
HKD1_k127_4964693_0 L-carnitine dehydratase bile acid-inducible protein F K07544,K07749 - 2.8.3.15,2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 301.0
HKD1_k127_4964693_1 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003921 235.0
HKD1_k127_4964693_2 TfoX N-terminal domain - - - 0.000000000000000001046 91.0
HKD1_k127_4966591_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000933 287.0
HKD1_k127_4966591_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006478 277.0
HKD1_k127_4966591_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000008407 256.0
HKD1_k127_4966591_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000004923 206.0
HKD1_k127_4966591_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000004162 105.0
HKD1_k127_4988283_0 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 426.0
HKD1_k127_4988283_1 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 397.0
HKD1_k127_4988283_2 AAA domain K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000004009 253.0
HKD1_k127_4988283_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000008193 114.0
HKD1_k127_4988283_4 Participates in transcription elongation, termination and antitermination K05785 - - 0.0000000000000000002131 95.0
HKD1_k127_4990123_0 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000004793 212.0
HKD1_k127_4990123_1 His Kinase A (phosphoacceptor) domain K20971 - - 0.000000000000000000000000000000000000000000000000224 188.0
HKD1_k127_4990123_2 HWE histidine kinase - - - 0.000000000000000000000000000002579 135.0
HKD1_k127_4990123_3 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000005276 95.0
HKD1_k127_4998583_0 conserved protein (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 386.0
HKD1_k127_4998583_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000001034 216.0
HKD1_k127_4998583_2 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000002222 150.0
HKD1_k127_4998583_3 - - - - 0.00000000001629 70.0
HKD1_k127_500271_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 445.0
HKD1_k127_500271_1 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000008411 157.0
HKD1_k127_500271_2 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000002067 100.0
HKD1_k127_5005608_0 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 533.0
HKD1_k127_5006277_0 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 589.0
HKD1_k127_5028204_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 563.0
HKD1_k127_5028204_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000003927 108.0
HKD1_k127_5035081_0 Cytochrome C and Quinol oxidase polypeptide I - - - 5.03e-271 842.0
HKD1_k127_5035081_1 Cytochrome c oxidase subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000003177 244.0
HKD1_k127_5035081_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000166 208.0
HKD1_k127_5035081_3 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000001961 158.0
HKD1_k127_5035081_5 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.0000000001614 62.0
HKD1_k127_5043907_0 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000134 153.0
HKD1_k127_5043907_1 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000004781 143.0
HKD1_k127_5043907_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023,K00059,K07535,K21883 - 1.1.1.100,1.1.1.36,1.1.1.401 0.0000000003016 63.0
HKD1_k127_5044970_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 535.0
HKD1_k127_5044970_1 IS66 Orf2 like protein K07484 - - 0.000000000000000000000000000000000000000000002293 167.0
HKD1_k127_5044970_2 Transposase K07483 - - 0.0000000000000000002769 93.0
HKD1_k127_5044970_3 Transposase - - - 0.000000002929 60.0
HKD1_k127_5046291_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.546e-251 782.0
HKD1_k127_5046291_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000004156 239.0
HKD1_k127_5046291_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000002371 162.0
HKD1_k127_5046291_3 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000002381 124.0
HKD1_k127_5047265_0 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 467.0
HKD1_k127_5047265_1 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 0.0000000000000000000000000000000000000000000001678 171.0
HKD1_k127_5062718_0 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0 1191.0
HKD1_k127_5062718_1 Catalase K03781 - 1.11.1.6 6.259e-265 822.0
HKD1_k127_5062718_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 404.0
HKD1_k127_5062718_3 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 336.0
HKD1_k127_5062718_4 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 299.0
HKD1_k127_5062718_5 efflux transmembrane transporter activity K15725 - - 0.000000000000000000000000000000000000000000000000000000000000005111 234.0
HKD1_k127_5062718_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.0000000000000000000001177 113.0
HKD1_k127_5066979_0 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 473.0
HKD1_k127_5066979_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000002772 273.0
HKD1_k127_5066979_2 Short-chain dehydrogenase reductase sdr K13774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003637 261.0
HKD1_k127_5066979_3 Ndr family - - - 0.000000000000000000000000001312 122.0
HKD1_k127_5066979_4 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.00000000000000000000018 104.0
HKD1_k127_5066979_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000402 49.0
HKD1_k127_506973_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 331.0
HKD1_k127_506973_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001513 280.0
HKD1_k127_506973_2 PFAM short-chain dehydrogenase reductase SDR K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004085 274.0
HKD1_k127_506973_3 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000009236 181.0
HKD1_k127_506973_4 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000001725 179.0
HKD1_k127_506973_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000008245 131.0
HKD1_k127_506973_6 DNA mediated transformation K04096 - - 0.000000000003569 74.0
HKD1_k127_506973_7 PA14 - - - 0.00002781 57.0
HKD1_k127_5074488_0 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 479.0
HKD1_k127_5082655_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 340.0
HKD1_k127_5082655_1 Phytanoyl-CoA dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 321.0
HKD1_k127_5082655_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000066 250.0
HKD1_k127_5082655_3 Protein of unknown function (DUF3108) - - - 0.000000000000000000003143 103.0
HKD1_k127_5082655_4 DNA-sulfur modification-associated - - - 0.0006326 49.0
HKD1_k127_5082655_5 - - - - 0.0007307 51.0
HKD1_k127_5086256_0 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 402.0
HKD1_k127_5086256_1 Arylsulfatase a K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 372.0
HKD1_k127_5086256_2 - - - - 0.0000000000000000000000000000000000000004298 159.0
HKD1_k127_5086256_3 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000006708 150.0
HKD1_k127_5086699_0 Circularly permuted ATP-grasp type 2 - - - 1.825e-215 693.0
HKD1_k127_5086699_1 PQQ enzyme repeat K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 537.0
HKD1_k127_5086699_2 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 460.0
HKD1_k127_5086699_3 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 469.0
HKD1_k127_5086699_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 352.0
HKD1_k127_5086699_5 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 295.0
HKD1_k127_5086699_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000001034 157.0
HKD1_k127_5086699_7 Pfam Methyltransferase - - - 0.0000000000000000000000000000198 128.0
HKD1_k127_5086699_8 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000005215 51.0
HKD1_k127_5101075_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 591.0
HKD1_k127_5101075_1 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 331.0
HKD1_k127_5101075_2 Carbohydrate-selective porin, OprB family K07267 - - 0.0000000000000000000000000000000000000000002612 183.0
HKD1_k127_5101075_3 cytochrome C peroxidase - - - 0.000000004767 65.0
HKD1_k127_5106765_0 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 357.0
HKD1_k127_5106765_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 331.0
HKD1_k127_5106765_2 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 314.0
HKD1_k127_5106765_3 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004142 293.0
HKD1_k127_5106765_4 COG0625 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001069 258.0
HKD1_k127_5106765_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000293 205.0
HKD1_k127_5106765_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000002962 166.0
HKD1_k127_5106765_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000005064 128.0
HKD1_k127_5106765_8 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000006926 125.0
HKD1_k127_5106765_9 Methyltransferase K00587 - 2.1.1.100 0.00001758 56.0
HKD1_k127_5108126_0 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 489.0
HKD1_k127_5108126_1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 374.0
HKD1_k127_5108126_2 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 340.0
HKD1_k127_5108126_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000004828 119.0
HKD1_k127_5108126_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000003282 99.0
HKD1_k127_5109290_0 tRNA synthetases class I (K) K01870 - 6.1.1.5 1.275e-219 698.0
HKD1_k127_5109290_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000007152 59.0
HKD1_k127_5112499_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 387.0
HKD1_k127_5112499_1 DNA-binding response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 380.0
HKD1_k127_5112499_2 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000000000000000004915 196.0
HKD1_k127_5112499_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000001161 153.0
HKD1_k127_5112499_4 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000001602 57.0
HKD1_k127_5121261_0 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 387.0
HKD1_k127_5121261_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 338.0
HKD1_k127_5121261_2 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 321.0
HKD1_k127_5135798_0 Epoxide hydrolase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 449.0
HKD1_k127_5135798_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 420.0
HKD1_k127_5135798_2 Protein of unknown function (DUF1298) - - - 0.0000000000000000000003947 101.0
HKD1_k127_5135798_3 Multidrug DMT transporter permease - - - 0.00002513 56.0
HKD1_k127_5136921_0 B12 binding domain K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 369.0
HKD1_k127_5136921_1 TIGRFAM alpha-L-glutamate ligase-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 317.0
HKD1_k127_5136921_2 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.00000000000000000000000000000000000000000000000000000005048 218.0
HKD1_k127_5136921_4 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.000000000009767 77.0
HKD1_k127_514317_0 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 404.0
HKD1_k127_514317_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000003603 64.0
HKD1_k127_5146715_0 COG1233 Phytoene dehydrogenase and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 595.0
HKD1_k127_5146715_1 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000005381 215.0
HKD1_k127_5146715_2 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000002889 225.0
HKD1_k127_5146715_3 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000007788 180.0
HKD1_k127_5146715_4 Protein of unknown function (DUF2834) - - - 0.000000000000000000000000000000000000004002 152.0
HKD1_k127_5152433_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 317.0
HKD1_k127_5152433_1 Protein of unknown function (DUF1329) - - - 0.000000000000000000000000000000000000004002 164.0
HKD1_k127_5179160_0 belongs to the sigma-70 factor family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 360.0
HKD1_k127_5179160_1 Short-chain dehydrogenase reductase sdr K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 326.0
HKD1_k127_5179160_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004334 265.0
HKD1_k127_5179160_3 - - - - 0.00000000000000000000000000000001709 136.0
HKD1_k127_5179160_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000001084 126.0
HKD1_k127_5179160_5 YCII-related domain - - - 0.00000000000000000000000005671 112.0
HKD1_k127_5179160_6 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000005332 119.0
HKD1_k127_5179160_7 DoxX-like family - - - 0.000000000000006658 85.0
HKD1_k127_5194823_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 557.0
HKD1_k127_5194823_1 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 353.0
HKD1_k127_5194823_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000003908 257.0
HKD1_k127_5194823_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002442 240.0
HKD1_k127_5194823_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000023 130.0
HKD1_k127_5194823_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000009525 85.0
HKD1_k127_5194823_6 Protein of unknown function (DUF3426) - - - 0.000000001959 69.0
HKD1_k127_5194823_7 Abhydrolase family - - - 0.0001007 52.0
HKD1_k127_5198478_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.646e-236 737.0
HKD1_k127_5198478_1 Cytochrome b(N-terminal)/b6/petB K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 385.0
HKD1_k127_5198478_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008526 265.0
HKD1_k127_5198478_3 PFAM Rieske 2Fe-2S iron-sulphur domain K03886 - - 0.000000000000000000000000000000000000000000000000000000000000000002271 229.0
HKD1_k127_5198478_4 cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000004524 218.0
HKD1_k127_5198478_5 PFAM Cytochrome c, class I K03889 - - 0.00000000000000000000000000000000000000000000000006206 198.0
HKD1_k127_5209361_0 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008502 385.0
HKD1_k127_5209361_1 4-phosphoerythronate dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003159 261.0
HKD1_k127_5209361_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000013 95.0
HKD1_k127_5209361_3 Periplasmic protein thiol disulfide oxidoreductase, DsbE subfamily - - - 0.00000000004322 77.0
HKD1_k127_5209361_4 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000008214 69.0
HKD1_k127_5217702_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 7.02e-249 773.0
HKD1_k127_5217702_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.396e-242 758.0
HKD1_k127_5217702_10 - - - - 0.00000000000000000000000000000000001886 138.0
HKD1_k127_5217702_11 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00000000000000000000000000000000007494 142.0
HKD1_k127_5217702_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000001247 124.0
HKD1_k127_5217702_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000001627 109.0
HKD1_k127_5217702_14 Polymer-forming cytoskeletal - - - 0.000000000000000000000003323 111.0
HKD1_k127_5217702_15 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.000000000000000000000009803 109.0
HKD1_k127_5217702_16 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000002274 97.0
HKD1_k127_5217702_17 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000004872 93.0
HKD1_k127_5217702_18 ATP synthase B/B' CF(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000166 83.0
HKD1_k127_5217702_19 - - - - 0.00006191 55.0
HKD1_k127_5217702_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 5.594e-227 720.0
HKD1_k127_5217702_3 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 344.0
HKD1_k127_5217702_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 347.0
HKD1_k127_5217702_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004319 264.0
HKD1_k127_5217702_6 Zinc-uptake complex component A periplasmic K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000006483 238.0
HKD1_k127_5217702_7 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000001823 237.0
HKD1_k127_5217702_8 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000007375 225.0
HKD1_k127_5217702_9 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K09817 - - 0.000000000000000000000000000000000000000000000001487 185.0
HKD1_k127_5218275_0 Enoyl-(Acyl carrier protein) reductase - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.00000000000000000000000008615 111.0
HKD1_k127_5218275_1 - - - - 0.000000000000000000001731 106.0
HKD1_k127_5218275_2 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.000000000000000003442 95.0
HKD1_k127_5221792_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 423.0
HKD1_k127_5221792_1 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000009195 202.0
HKD1_k127_5221792_2 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0000000000000000000000000000000000000000000002407 170.0
HKD1_k127_5221792_3 - - - - 0.00000000000000000000000000001005 138.0
HKD1_k127_5221792_4 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000001101 72.0
HKD1_k127_5221792_5 antibiotic catabolic process K01406,K02414,K07004,K13277,K21449 - 3.4.24.40 0.0004116 53.0
HKD1_k127_5225966_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 443.0
HKD1_k127_5225966_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 302.0
HKD1_k127_5225966_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000002743 161.0
HKD1_k127_5225966_3 Nudix hydrolase - - - 0.00000000000000000000000000000000004322 149.0
HKD1_k127_5225966_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000001362 129.0
HKD1_k127_5225966_5 - - - - 0.0000000000000000005062 92.0
HKD1_k127_5248913_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.651e-278 881.0
HKD1_k127_5248913_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 3.266e-204 648.0
HKD1_k127_5248913_10 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.00009193 55.0
HKD1_k127_5248913_11 - - - - 0.0007961 48.0
HKD1_k127_5248913_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 567.0
HKD1_k127_5248913_3 COG3335 Transposase and inactivated derivatives K07494 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 524.0
HKD1_k127_5248913_4 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 497.0
HKD1_k127_5248913_5 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 416.0
HKD1_k127_5248913_6 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 308.0
HKD1_k127_5248913_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000005504 154.0
HKD1_k127_5248913_8 SnoaL-like domain - - - 0.000000000000000562 84.0
HKD1_k127_5248913_9 His Kinase A (phosphoacceptor) domain - - - 0.00000009028 64.0
HKD1_k127_5251084_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 389.0
HKD1_k127_5251084_1 CHAD domain containing protein - - - 0.00000000000000000000000000000000000000003322 171.0
HKD1_k127_5251084_2 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000001864 104.0
HKD1_k127_5251084_3 self proteolysis - - - 0.00000005355 66.0
HKD1_k127_5266728_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 452.0
HKD1_k127_5266728_1 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 398.0
HKD1_k127_5266728_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 399.0
HKD1_k127_5266728_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000002857 263.0
HKD1_k127_5285016_0 Retinal pigment epithelial membrane protein K11159 - - 4.866e-240 750.0
HKD1_k127_5285016_1 Regulator of ribonuclease activity B - - - 0.0000000016 67.0
HKD1_k127_528624_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 351.0
HKD1_k127_528624_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002579 289.0
HKD1_k127_528624_2 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002847 298.0
HKD1_k127_528624_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000001926 281.0
HKD1_k127_528624_4 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000213 280.0
HKD1_k127_528624_5 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001083 233.0
HKD1_k127_528624_6 SCO1/SenC K07152,K08976 - - 0.0000000000000000000000000000000000000268 158.0
HKD1_k127_528624_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000005362 139.0
HKD1_k127_528624_8 Bifunctional nuclease K08999 - - 0.00000000000000000000000000006544 126.0
HKD1_k127_528624_9 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000005695 116.0
HKD1_k127_5295136_0 Large extracellular alpha-helical protein K06894 - - 0.0 1076.0
HKD1_k127_5306539_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 411.0
HKD1_k127_5306539_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 339.0
HKD1_k127_5306539_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000001424 251.0
HKD1_k127_5306539_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000004338 163.0
HKD1_k127_5306539_4 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000003259 138.0
HKD1_k127_5306539_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000003953 122.0
HKD1_k127_5306539_6 TonB C terminal K03646 - - 0.00003284 54.0
HKD1_k127_530851_0 NLP P60 protein - - - 1.817e-195 629.0
HKD1_k127_530851_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 445.0
HKD1_k127_530851_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 368.0
HKD1_k127_530851_3 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002439 264.0
HKD1_k127_530851_4 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000003173 254.0
HKD1_k127_530851_5 Belongs to the GST superfamily K11209 - - 0.000000000000001465 78.0
HKD1_k127_5323443_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K17228 - 1.14.14.35 0.000000000000000000000000000000000000000000002326 172.0
HKD1_k127_5323443_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000005225 83.0
HKD1_k127_534476_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 2.605e-203 644.0
HKD1_k127_534476_1 transcriptional regulator K10913 - - 0.00000000000000000000000004501 115.0
HKD1_k127_534476_2 gamma-glutamylcyclotransferase activity K22120 GO:0006518,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0019748,GO:0034641,GO:0043043,GO:0043385,GO:0043386,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044550,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:2001308,GO:2001310 - 0.00000000000000001544 90.0
HKD1_k127_534476_3 Helix-hairpin-helix motif K02237 - - 0.000801 49.0
HKD1_k127_5356361_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 460.0
HKD1_k127_5356361_1 TIGRFAM RHS repeat-associated core - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 333.0
HKD1_k127_5362936_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000003028 141.0
HKD1_k127_5362936_1 synthase K16167 - - 0.000000000006943 77.0
HKD1_k127_5372486_0 Sulfotransferase domain K01014 - 2.8.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 529.0
HKD1_k127_5372486_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 525.0
HKD1_k127_5372486_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 455.0
HKD1_k127_5372486_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 424.0
HKD1_k127_5372486_4 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000001123 251.0
HKD1_k127_5372486_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000322 137.0
HKD1_k127_5372486_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000005625 136.0
HKD1_k127_5372486_7 COG0346 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.00000000000000000005348 101.0
HKD1_k127_5372486_8 Essential cell division protein K03589 - - 0.000000000000001104 91.0
HKD1_k127_5372486_9 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000002231 64.0
HKD1_k127_5407277_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00055 - 1.1.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 392.0
HKD1_k127_5407277_1 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 325.0
HKD1_k127_5407277_2 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 296.0
HKD1_k127_5407277_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007437 283.0
HKD1_k127_5407277_4 Abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000006607 243.0
HKD1_k127_5407277_5 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000003854 180.0
HKD1_k127_5407277_6 chlorophyll binding - - - 0.000000000000000000000000000000000000001087 170.0
HKD1_k127_5407277_7 GMC oxidoreductase - - - 0.000000002609 59.0
HKD1_k127_5431713_0 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 400.0
HKD1_k127_5431713_1 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000007536 212.0
HKD1_k127_5431713_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000001566 179.0
HKD1_k127_5431713_3 Histidine kinase K07768 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 0.000000005114 58.0
HKD1_k127_5432338_0 FAD binding domain K16022,K20943 - 1.14.13.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 528.0
HKD1_k127_5432338_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 459.0
HKD1_k127_5432338_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K16066 - 1.1.1.381 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 330.0
HKD1_k127_5432338_3 signal transduction histidine kinase K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000001586 181.0
HKD1_k127_5432338_4 - - - - 0.0000000000000000000000000000000000000000003655 164.0
HKD1_k127_5432338_5 Protein of unknown function (DUF2834) - - - 0.0000000000006846 74.0
HKD1_k127_5439806_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 616.0
HKD1_k127_5439806_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003236 266.0
HKD1_k127_5439806_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000005636 244.0
HKD1_k127_5439806_3 Biotin-lipoyl like - - - 0.0000000000000000000004928 111.0
HKD1_k127_5439806_4 type I secretion outer membrane protein, TolC K12543 - - 0.00000003378 67.0
HKD1_k127_545297_0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 427.0
HKD1_k127_545297_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 420.0
HKD1_k127_545297_2 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000001519 122.0
HKD1_k127_5454391_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 429.0
HKD1_k127_5454391_1 PFAM peptidase M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 392.0
HKD1_k127_5454391_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 343.0
HKD1_k127_5454391_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000225 240.0
HKD1_k127_5454391_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000001892 132.0
HKD1_k127_5454391_5 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.000000000000000000000006021 117.0
HKD1_k127_5454391_6 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000003644 100.0
HKD1_k127_5454391_7 Belongs to the BolA IbaG family K05527 - - 0.000000000000000003507 96.0
HKD1_k127_5454391_8 Receptor K02014 - - 0.0000000001229 74.0
HKD1_k127_5459018_0 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 598.0
HKD1_k127_5459018_1 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003371 263.0
HKD1_k127_5459018_2 isochorismatase - - - 0.0000000000000000000000000000000000000004458 156.0
HKD1_k127_5459018_3 Amidohydrolase K07045 - - 0.0000000000009318 70.0
HKD1_k127_5465639_0 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K07027,K14205 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 9.634e-251 799.0
HKD1_k127_5465639_1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 614.0
HKD1_k127_5465639_10 peptidyl-tyrosine sulfation K15773 - - 0.00002281 51.0
HKD1_k127_5465639_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008961 413.0
HKD1_k127_5465639_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 339.0
HKD1_k127_5465639_4 Bacterial virulence protein (VirJ) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 339.0
HKD1_k127_5465639_5 metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 301.0
HKD1_k127_5465639_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002848 285.0
HKD1_k127_5465639_7 Cupin domain - - - 0.00000000000000000000000000002944 120.0
HKD1_k127_5465639_8 chlorophyll binding - - - 0.000005756 55.0
HKD1_k127_5465639_9 Auxin binding protein - - - 0.00002196 47.0
HKD1_k127_5472456_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 522.0
HKD1_k127_5472456_1 Glucokinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 295.0
HKD1_k127_5472456_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004978 247.0
HKD1_k127_5472456_3 -acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000006695 246.0
HKD1_k127_5476946_0 Transcriptional regulator K03603,K05799 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043207,GO:0043565,GO:0044403,GO:0044419,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000001168 200.0
HKD1_k127_5476946_1 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000001034 207.0
HKD1_k127_549545_0 Anthranilate synthase component I K01657,K01665 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000009417 202.0
HKD1_k127_549545_1 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.0000000000000000000000000000000000002355 153.0
HKD1_k127_5500040_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.52e-215 691.0
HKD1_k127_5500040_1 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008397 355.0
HKD1_k127_5508609_0 - - - - 0.0 1155.0
HKD1_k127_5508609_1 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 336.0
HKD1_k127_5508609_10 Fungalysin metallopeptidase (M36) - - - 0.0000000000000000000000004562 124.0
HKD1_k127_5508609_11 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000009073 110.0
HKD1_k127_5508609_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 302.0
HKD1_k127_5508609_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 310.0
HKD1_k127_5508609_4 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004228 259.0
HKD1_k127_5508609_5 PFAM Glycosyl transferase, group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000008605 228.0
HKD1_k127_5508609_6 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000003817 215.0
HKD1_k127_5508609_7 UDP-glucoronosyl and UDP-glucosyl transferase K14596 - 2.4.1.276 0.000000000000000000000000000000000005201 158.0
HKD1_k127_5508609_8 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000001646 147.0
HKD1_k127_5508609_9 belongs to the thiolase family K08764 GO:0000038,GO:0000062,GO:0000166,GO:0001676,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0003824,GO:0003988,GO:0005102,GO:0005215,GO:0005319,GO:0005488,GO:0005496,GO:0005504,GO:0005515,GO:0005548,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005777,GO:0005782,GO:0005783,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006699,GO:0006700,GO:0006701,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006886,GO:0006996,GO:0007031,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008207,GO:0008289,GO:0008306,GO:0008355,GO:0008525,GO:0008526,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009719,GO:0009725,GO:0009791,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010817,GO:0010876,GO:0010883,GO:0010888,GO:0010893,GO:0010941,GO:0010942,GO:0012505,GO:0014070,GO:0015031,GO:0015248,GO:0015485,GO:0015711,GO:0015748,GO:0015833,GO:0015850,GO:0015914,GO:0015918,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016137,GO:0016138,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0017127,GO:0017144,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019395,GO:0019637,GO:0019693,GO:0019748,GO:0019751,GO:0019752,GO:0019867,GO:0019898,GO:0022611,GO:0030258,GO:0030301,GO:0030554,GO:0031090,GO:0031312,GO:0031315,GO:0031406,GO:0031907,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032101,GO:0032355,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032377,GO:0032379,GO:0032380,GO:0032382,GO:0032383,GO:0032385,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032879,GO:0032934,GO:0032957,GO:0032958,GO:0032959,GO:0032991,GO:0033036,GO:0033218,GO:0033293,GO:0033365,GO:0033540,GO:0033559,GO:0033814,GO:0033865,GO:0033875,GO:0033993,GO:0034032,GO:0034440,GO:0034613,GO:0034641,GO:0034698,GO:0034699,GO:0034754,GO:0035383,GO:0036041,GO:0036042,GO:0036094,GO:0036109,GO:0036314,GO:0036315,GO:0040008,GO:0040012,GO:0040024,GO:0042048,GO:0042180,GO:0042181,GO:0042221,GO:0042445,GO:0042446,GO:0042448,GO:0042579,GO:0042802,GO:0042803,GO:0042810,GO:0042811,GO:0042886,GO:0042981,GO:0043053,GO:0043054,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043177,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043434,GO:0043436,GO:0043574,GO:0043603,GO:0043647,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044550,GO:0045184,GO:0045540,GO:0045542,GO:0045834,GO:0045927,GO:0045940,GO:0046165,GO:0046173,GO:0046394,GO:0046395,GO:0046483,GO:0046889,GO:0046890,GO:0046907,GO:0046982,GO:0046983,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048580,GO:0048582,GO:0048583,GO:0048638,GO:0048639,GO:0048856,GO:0050632,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050810,GO:0050877,GO:0050890,GO:0050896,GO:0050920,GO:0051049,GO:0051050,GO:0051094,GO:0051179,GO:0051186,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0055115,GO:0060341,GO:0060620,GO:0061062,GO:0061063,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070013,GO:0070538,GO:0070723,GO:0070727,GO:0070887,GO:0071310,GO:0071396,GO:0071397,GO:0071407,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071981,GO:0072329,GO:0072330,GO:0072521,GO:0072594,GO:0072657,GO:0072659,GO:0072662,GO:0072663,GO:0080090,GO:0090181,GO:0090205,GO:0090407,GO:0097159,GO:0097305,GO:0097306,GO:0097367,GO:0098588,GO:0098805,GO:0106118,GO:0106120,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901373,GO:1901564,GO:1901567,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901652,GO:1901657,GO:1901659,GO:1901681,GO:1901698,GO:1901700,GO:1901701,GO:1902930,GO:1902932,GO:1904069,GO:1904070,GO:1904109,GO:1904121,GO:1905952,GO:1905953,GO:1905954,GO:1990778,GO:2000026,GO:2000909,GO:2000911 2.3.1.176 0.00000000000000000000000000003271 118.0
HKD1_k127_5512552_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 490.0
HKD1_k127_5512552_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 419.0
HKD1_k127_5512552_2 - - - - 0.000000000000000000000000000000000000000000000000000000000001688 223.0
HKD1_k127_5512552_3 Glycosyl transferase family 11 - - - 0.00000000000000000000000000000000000000000000000003189 190.0
HKD1_k127_5512552_4 Glycosyl transferase family 2 - - - 0.000000000000000000000000001994 131.0
HKD1_k127_551269_0 Aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 403.0
HKD1_k127_551269_1 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 340.0
HKD1_k127_551269_2 2OG-Fe(II) oxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000495 274.0
HKD1_k127_555619_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 567.0
HKD1_k127_555619_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000143 221.0
HKD1_k127_555619_2 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000005321 211.0
HKD1_k127_555619_3 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.000000000000000000004872 96.0
HKD1_k127_555619_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.0000000000000443 84.0
HKD1_k127_555619_5 VanZ like family - - - 0.0000001876 62.0
HKD1_k127_555619_6 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.0000004698 62.0
HKD1_k127_5581247_0 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 364.0
HKD1_k127_5581247_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 347.0
HKD1_k127_5581247_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001115 273.0
HKD1_k127_5581247_3 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000001901 54.0
HKD1_k127_5598264_0 NnrS protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 338.0
HKD1_k127_5598264_1 Electron transfer flavoprotein alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000003022 248.0
HKD1_k127_5598264_2 PFAM Glycosyl transferases group 1 K16703 - - 0.0000000000000000000000000000000000000000000000000000000000001248 229.0
HKD1_k127_5598264_3 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000000000000000000000000004724 135.0
HKD1_k127_5607692_0 HAMP domain - - - 0.000000000000000000000000000007997 121.0
HKD1_k127_5607692_1 cheY-homologous receiver domain - - - 0.000000000000000000000000003293 120.0
HKD1_k127_5607692_2 cheY-homologous receiver domain - - - 0.0000000000000000000000006196 114.0
HKD1_k127_5614227_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 410.0
HKD1_k127_5614227_1 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 349.0
HKD1_k127_5614227_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 316.0
HKD1_k127_5614227_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000269 126.0
HKD1_k127_5614227_4 C-terminal domain of CHU protein family - - - 0.000000578 56.0
HKD1_k127_5618170_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000002129 175.0
HKD1_k127_5618170_1 - - - - 0.000000000000000000000000000000000000000002167 179.0
HKD1_k127_5618170_2 Class I peptide chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000002442 132.0
HKD1_k127_5618170_3 Histidine Phosphotransfer domain K02487,K03407,K06596 - 2.7.13.3 0.000000000000000000000000000001127 136.0
HKD1_k127_5618170_4 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000002609 100.0
HKD1_k127_5643971_0 PFAM Glycoside hydrolase 15-related - - - 5.54e-292 930.0
HKD1_k127_5643971_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 407.0
HKD1_k127_5643971_2 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 303.0
HKD1_k127_5643971_3 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000893 165.0
HKD1_k127_5643971_4 COG3459 Cellobiose phosphorylase - - - 0.0000000000000001436 95.0
HKD1_k127_5643971_5 Outer membrane lipoprotein-sorting protein - - - 0.000000000000002185 86.0
HKD1_k127_5674707_0 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 488.0
HKD1_k127_5674707_1 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000002842 211.0
HKD1_k127_5674707_2 TonB system transport protein ExbB TolQ K03561 - - 0.0000000000000000000000000000000000000000000000000001262 195.0
HKD1_k127_5674707_3 Transcriptional regulator K21703 - - 0.00000000000000000000000000000000000000000000552 176.0
HKD1_k127_5674707_4 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000006585 130.0
HKD1_k127_5674707_5 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000001551 98.0
HKD1_k127_5674707_6 Transcriptional regulatory protein, C terminal K07776 - - 0.0000000000000006793 83.0
HKD1_k127_5674707_7 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.00000000004516 73.0
HKD1_k127_5674707_8 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000003796 70.0
HKD1_k127_5676754_0 Glucose sorbosone - - - 0.000000008067 68.0
HKD1_k127_5676754_1 PBS lyase HEAT-like repeat - - - 0.00002057 55.0
HKD1_k127_5690079_0 Enoyl-CoA hydratase/isomerase K08299 - 4.2.1.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009688 308.0
HKD1_k127_5690079_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 308.0
HKD1_k127_5690079_2 PFAM thioesterase superfamily K02614 - - 0.000004691 55.0
HKD1_k127_5704134_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 3.439e-241 753.0
HKD1_k127_5704134_1 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000002032 184.0
HKD1_k127_5713365_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 6.871e-293 926.0
HKD1_k127_5713365_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 542.0
HKD1_k127_5713365_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 385.0
HKD1_k127_5713365_3 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000008371 222.0
HKD1_k127_5713365_4 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000005363 172.0
HKD1_k127_5713365_5 Zincin-like metallopeptidase - - - 0.0000000000000000000000000003375 117.0
HKD1_k127_5713365_6 Lysine methyltransferase - - - 0.0000000000000000000003642 109.0
HKD1_k127_5735772_0 MMPL family - - - 1.443e-295 941.0
HKD1_k127_5735772_1 RecQ zinc-binding K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 366.0
HKD1_k127_5735772_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000005094 218.0
HKD1_k127_5744916_0 Cadherin repeats. - - - 0.000000000000000000000000000000000000000001617 179.0
HKD1_k127_5744916_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000006271 58.0
HKD1_k127_5773704_0 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007326 276.0
HKD1_k127_5773704_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000008589 280.0
HKD1_k127_5773704_10 - - - - 0.000000000000000000000000000000002695 144.0
HKD1_k127_5773704_12 transcriptional regulator - - - 0.0000000000000000007465 92.0
HKD1_k127_5773704_13 PFAM CobQ CobB MinD ParA nucleotide binding domain - - - 0.000002408 53.0
HKD1_k127_5773704_14 -O-antigen - - - 0.0001182 54.0
HKD1_k127_5773704_2 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001331 261.0
HKD1_k127_5773704_3 Glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000001689 254.0
HKD1_k127_5773704_4 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000001608 205.0
HKD1_k127_5773704_5 Protein of unknown function (DUF1428) - - - 0.00000000000000000000000000000000000000000000000002152 186.0
HKD1_k127_5773704_6 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000004628 199.0
HKD1_k127_5773704_7 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000001278 194.0
HKD1_k127_5773704_8 oxidoreductase activity K21883 - 1.1.1.401 0.0000000000000000000000000000000000000000002662 169.0
HKD1_k127_5773704_9 Protein of unknown function (DUF2878) - - - 0.0000000000000000000000000000000000005484 147.0
HKD1_k127_5797582_0 of the RND superfamily K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 477.0
HKD1_k127_5797582_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 426.0
HKD1_k127_5797582_10 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000003554 149.0
HKD1_k127_5797582_11 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.000000000000000000006363 104.0
HKD1_k127_5797582_2 N-acyl-D-aspartate D-glutamate deacylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 426.0
HKD1_k127_5797582_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 391.0
HKD1_k127_5797582_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 314.0
HKD1_k127_5797582_5 PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 293.0
HKD1_k127_5797582_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K05551 - 2.3.1.235,2.3.1.260 0.000000000000000000000000000000000000000000000000000000000000000000002854 251.0
HKD1_k127_5797582_7 Transcriptional regulator, CarD family K07736 - - 0.000000000000000000000000000000000000000000000000000002049 195.0
HKD1_k127_5797582_8 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000001315 176.0
HKD1_k127_5797582_9 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000001984 171.0
HKD1_k127_5799187_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 440.0
HKD1_k127_5799187_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 334.0
HKD1_k127_5799187_2 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001393 295.0
HKD1_k127_5799187_3 galactokinase activity K00849,K17781,K18674 GO:0000409,GO:0000411,GO:0000429,GO:0000431,GO:0000435,GO:0000436,GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005975,GO:0005996,GO:0006012,GO:0006355,GO:0006357,GO:0006793,GO:0006796,GO:0007154,GO:0007584,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019219,GO:0019222,GO:0019318,GO:0019320,GO:0019388,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0031982,GO:0033036,GO:0033499,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043230,GO:0043231,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044421,GO:0044424,GO:0044464,GO:0045185,GO:0045893,GO:0045935,GO:0045944,GO:0045990,GO:0045991,GO:0046365,GO:0046835,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051179,GO:0051235,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070062,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:1901575,GO:1902680,GO:1903506,GO:1903508,GO:1903561,GO:2000112,GO:2001141 2.7.1.157,2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000001941 260.0
HKD1_k127_5799187_4 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K04042,K16881 - 2.3.1.157,2.7.7.13,2.7.7.23,5.4.2.8 0.000000000000000000000000000000000000000000000000000000007713 206.0
HKD1_k127_5799187_5 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000002252 117.0
HKD1_k127_5799187_6 von Willebrand factor (vWF) type A domain - - - 0.00000000000000005841 93.0
HKD1_k127_5799187_7 Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000795 77.0
HKD1_k127_5799187_8 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000002939 65.0
HKD1_k127_5799187_9 - - - - 0.00000005182 66.0
HKD1_k127_583585_0 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 340.0
HKD1_k127_583585_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000001172 157.0
HKD1_k127_583585_2 ECF sigma factor K03088 - - 0.000000000000000000000000000003165 130.0
HKD1_k127_583585_3 SbmA/BacA-like family - - - 0.00000000000000000002749 96.0
HKD1_k127_583585_4 Protein of unknown function (DUF1109) - - - 0.000454 52.0
HKD1_k127_5876014_0 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 356.0
HKD1_k127_5876014_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 342.0
HKD1_k127_5900195_0 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 404.0
HKD1_k127_5900195_1 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000002829 171.0
HKD1_k127_5900195_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000003196 129.0
HKD1_k127_5900195_3 response to nickel cation - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0040008,GO:0045926,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0065007,GO:0097159,GO:1901363 - 0.00000000000000002828 84.0
HKD1_k127_5908917_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 378.0
HKD1_k127_5908917_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001109 275.0
HKD1_k127_5908917_2 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005707 254.0
HKD1_k127_5908917_3 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000005911 228.0
HKD1_k127_5908917_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000002309 166.0
HKD1_k127_5908917_5 Glutathione S-transferase, C-terminal domain K03599 - - 0.000000000000000000000000000005557 126.0
HKD1_k127_5908917_6 BFD-like [2Fe-2S] binding domain - - - 0.0000002535 56.0
HKD1_k127_59290_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.744e-229 720.0
HKD1_k127_59290_1 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002249 276.0
HKD1_k127_59290_2 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000291 225.0
HKD1_k127_59290_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000901 183.0
HKD1_k127_59290_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000001337 176.0
HKD1_k127_59290_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000009824 160.0
HKD1_k127_59290_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000001044 113.0
HKD1_k127_59290_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000003016 86.0
HKD1_k127_5933489_0 Squalene-hopene cyclase C-terminal domain K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 1.438e-230 732.0
HKD1_k127_5933489_1 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 387.0
HKD1_k127_5933489_10 Histidine kinase K07716 - 2.7.13.3 0.0000000000908 75.0
HKD1_k127_5933489_11 Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' K00231,K00514,K02293,K09879,K21677 - 1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6 0.0000001368 61.0
HKD1_k127_5933489_12 PhoQ Sensor - - - 0.000000281 64.0
HKD1_k127_5933489_13 Phosphorylase superfamily K01243 - 3.2.2.9 0.000001035 59.0
HKD1_k127_5933489_2 lipid-transfer protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 361.0
HKD1_k127_5933489_3 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 340.0
HKD1_k127_5933489_4 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009582 264.0
HKD1_k127_5933489_5 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000184 268.0
HKD1_k127_5933489_6 Squalene/phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002249 256.0
HKD1_k127_5933489_7 KR domain K07535 - - 0.000000000000000000000000000000000000000000000000000000001576 210.0
HKD1_k127_5933489_8 serine-type aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000001427 214.0
HKD1_k127_5933489_9 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000004706 110.0
HKD1_k127_5943572_0 Uncharacterized ACR, YdiU/UPF0061 family - - - 1.515e-208 660.0
HKD1_k127_5943572_1 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 1.255e-203 648.0
HKD1_k127_5943572_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 594.0
HKD1_k127_5943572_3 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 472.0
HKD1_k127_5943572_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 359.0
HKD1_k127_5943572_5 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 347.0
HKD1_k127_5943572_6 Dynamin family - - - 0.0000000000000000000000000000000000000000000012 186.0
HKD1_k127_5943572_7 - - - - 0.0000000000000000000000000008639 123.0
HKD1_k127_5943572_8 Universal stress protein - - - 0.000000000000000002785 95.0
HKD1_k127_5943572_9 PFAM pentapeptide repeat protein - - - 0.0000000381 68.0
HKD1_k127_5950739_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 396.0
HKD1_k127_5950739_1 GAF domain - - - 0.0000000000000000000000000000000000000000003825 170.0
HKD1_k127_5998672_0 Carbamoyltransferase C-terminus K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 397.0
HKD1_k127_5998672_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000001204 184.0
HKD1_k127_5998672_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000003588 111.0
HKD1_k127_6082836_0 COG0208 Ribonucleotide reductase, beta subunit - - - 0.000000000000000000001474 108.0
HKD1_k127_6082836_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000004178 81.0
HKD1_k127_6082836_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000008896 83.0
HKD1_k127_6095159_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 384.0
HKD1_k127_6095159_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 323.0
HKD1_k127_6095159_2 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000002839 215.0
HKD1_k127_6095159_3 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000002419 191.0
HKD1_k127_6095159_4 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000000000000000000000000000000000000001045 183.0
HKD1_k127_6095159_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000001985 177.0
HKD1_k127_6095159_6 PFAM RNA recognition motif - - - 0.0000000000000000000000004427 108.0
HKD1_k127_6096419_0 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 381.0
HKD1_k127_6096419_1 - - - - 0.000000000000000000000000000000002948 141.0
HKD1_k127_6097532_0 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 329.0
HKD1_k127_6097532_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 310.0
HKD1_k127_6097532_2 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000157 266.0
HKD1_k127_6098175_0 Flavin-binding monooxygenase-like - - - 2.813e-239 748.0
HKD1_k127_6098175_1 lipid-transfer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 467.0
HKD1_k127_6098175_2 glutathione transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 310.0
HKD1_k127_6098175_3 response regulator receiver K13041 - - 0.00000000000000000000000000000000000000000000000000000000000000002952 230.0
HKD1_k127_6098175_4 nucleic-acid-binding protein containing a zn-ribbon K07068 - - 0.00000000000000000000000000000000001702 142.0
HKD1_k127_6098175_5 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000003699 122.0
HKD1_k127_6098175_6 Phage integrase family - - - 0.0000000000000003553 81.0
HKD1_k127_6098175_7 extracellular matrix structural constituent - - - 0.00003004 54.0
HKD1_k127_6102296_0 DNA polymerase type-B family K02336 - 2.7.7.7 2.286e-257 814.0
HKD1_k127_6102296_1 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 467.0
HKD1_k127_6102296_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 335.0
HKD1_k127_6102296_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000614 160.0
HKD1_k127_6102296_4 Protein of unknown function (DUF507) - - - 0.0000000009404 66.0
HKD1_k127_6114580_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 3.343e-204 670.0
HKD1_k127_6114580_1 MreB/Mbl protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 603.0
HKD1_k127_6114580_2 Belongs to the heat shock protein 70 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 604.0
HKD1_k127_6114580_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 463.0
HKD1_k127_6114580_4 Belongs to the heat shock protein 70 family - - - 0.000000000000000000000000000000000000000000000000000000000000000003926 237.0
HKD1_k127_6114580_5 Domain of unknown function (DUF2760) - - - 0.000000000000000000000000000000000001595 148.0
HKD1_k127_6114580_6 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000001182 140.0
HKD1_k127_6130413_0 Protein of unknown function, DUF255 K06888 - - 3.161e-221 705.0
HKD1_k127_6130413_1 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 610.0
HKD1_k127_6130413_2 arsenite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 353.0
HKD1_k127_6130413_3 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000625 243.0
HKD1_k127_6130413_4 Nitroreductase family K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000000000000000000000268 247.0
HKD1_k127_6130413_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000005572 153.0
HKD1_k127_6130413_6 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.000000000000000000000000000000000002971 150.0
HKD1_k127_6130413_7 Survival protein SurE K03787 - 3.1.3.5 0.000000000000000000000000000000003929 142.0
HKD1_k127_6130413_8 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000221 74.0
HKD1_k127_6130413_9 Acetyl xylan esterase (AXE1) - - - 0.000000005358 69.0
HKD1_k127_6163666_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000189 202.0
HKD1_k127_6163666_1 NnrU protein - - - 0.00000000000000000000000000000000000000000000005189 173.0
HKD1_k127_6163666_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000002232 69.0
HKD1_k127_6170070_0 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 562.0
HKD1_k127_6170070_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 497.0
HKD1_k127_6170070_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 304.0
HKD1_k127_6170070_3 malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003551 279.0
HKD1_k127_6170070_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000001572 226.0
HKD1_k127_6180993_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 304.0
HKD1_k127_6180993_1 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000005981 252.0
HKD1_k127_6180993_2 PFAM glycosyl transferase, family 9 K02841 - - 0.000000000000000000000000000000000000000000000001054 193.0
HKD1_k127_6180993_3 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.00000000000000000000000000000000000407 147.0
HKD1_k127_6180993_4 Glycosyltransferase like family 2 - - - 0.000000000000000000003297 96.0
HKD1_k127_6190168_0 phosphorelay signal transduction system K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 388.0
HKD1_k127_6190168_1 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 311.0
HKD1_k127_6190168_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000357 237.0
HKD1_k127_6190168_3 (2R)-phospho-3-sulfolactate synthase (ComA) K08097 - 4.4.1.19 0.0000000000000000000000000000000000000000000003099 169.0
HKD1_k127_6190168_4 KR domain K07124 - - 0.000000000000000000000000000000000000000001858 169.0
HKD1_k127_6190168_5 GAF domain - - - 0.000000000000000000000000000000000000000003733 179.0
HKD1_k127_6190168_6 Cytochrome P450 - - - 0.0000000000007618 75.0
HKD1_k127_6190168_7 Periplasmic copper-binding protein (NosD) - - - 0.0002204 55.0
HKD1_k127_6200110_1 Flavoprotein involved in K transport K03379 - 1.14.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 521.0
HKD1_k127_6200110_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 483.0
HKD1_k127_6200110_3 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 409.0
HKD1_k127_6200110_4 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 349.0
HKD1_k127_6200110_5 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002438 275.0
HKD1_k127_6200110_7 thiolester hydrolase activity - - - 0.0000000001366 65.0
HKD1_k127_6200110_9 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000007089 57.0
HKD1_k127_6211920_0 Coenzyme A transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 414.0
HKD1_k127_6211920_1 - - - - 0.00000000000000000000000000000000000000000000009908 185.0
HKD1_k127_6216142_0 Anion-transporting ATPase - - - 0.000000000000000000000000000000000000000000000000000000004292 218.0
HKD1_k127_6216142_1 Pfam Anion-transporting ATPase - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000001497 138.0
HKD1_k127_6216142_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000001782 81.0
HKD1_k127_6216288_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 337.0
HKD1_k127_6216288_1 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000008888 251.0
HKD1_k127_6216288_2 Transcriptional regulator - - - 0.00000000000000000048 101.0
HKD1_k127_6216288_3 cheY-homologous receiver domain - - - 0.00000000000000001355 97.0
HKD1_k127_6219375_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 522.0
HKD1_k127_6219375_1 PFAM malic protein domain protein K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 484.0
HKD1_k127_6219375_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001488 245.0
HKD1_k127_622845_0 Histidine kinase - - - 0.00000000000000000000000000000000000002027 154.0
HKD1_k127_6248111_0 COG2015 Alkyl sulfatase and related hydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 542.0
HKD1_k127_6248111_1 Histidine kinase - - - 0.000000000000000000004312 93.0
HKD1_k127_6259748_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 537.0
HKD1_k127_6259748_1 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 520.0
HKD1_k127_6259748_2 cytochrome p450 K20497 GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0006066,GO:0006082,GO:0006629,GO:0006631,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0009987,GO:0010430,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0019395,GO:0019752,GO:0020037,GO:0030258,GO:0031073,GO:0032787,GO:0034440,GO:0036094,GO:0036199,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044282,GO:0046164,GO:0046906,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070402,GO:0071704,GO:0097089,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901615,GO:1901616,GO:1902652 1.14.15.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 462.0
HKD1_k127_6259748_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 386.0
HKD1_k127_6259748_4 Acetyl xylan esterase (AXE1) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 335.0
HKD1_k127_6259748_5 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000001189 232.0
HKD1_k127_626114_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - - 9.83e-286 899.0
HKD1_k127_626114_1 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 393.0
HKD1_k127_626114_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 362.0
HKD1_k127_626114_3 proteins, LmbE homologs - - - 0.000001698 59.0
HKD1_k127_6267141_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 558.0
HKD1_k127_6267141_1 transport protein CorA K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 377.0
HKD1_k127_6267141_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 317.0
HKD1_k127_6267141_3 possibly involved in detoxification reactions following oxidative damage to lipids - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 289.0
HKD1_k127_6267141_4 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000001163 224.0
HKD1_k127_6267141_5 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000001915 184.0
HKD1_k127_6267141_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000005001 111.0
HKD1_k127_6271097_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 293.0
HKD1_k127_6271097_1 COG0534 Na -driven multidrug efflux pump K03327 - - 0.0000000000000000000000000000000000000000000000000000004428 197.0
HKD1_k127_6271097_2 histidine kinase A domain protein - - - 0.00000000000000000000002565 109.0
HKD1_k127_6271097_3 Protein of unknown function (DUF1328) - - - 0.000000000000003879 78.0
HKD1_k127_6271097_4 - - - - 0.0000005163 55.0
HKD1_k127_6272855_0 Aldehyde dehydrogenase family - - - 5.975e-204 654.0
HKD1_k127_6272855_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 426.0
HKD1_k127_6272855_10 Septum formation initiator - - - 0.00001926 51.0
HKD1_k127_6272855_2 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 385.0
HKD1_k127_6272855_3 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 375.0
HKD1_k127_6272855_4 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 359.0
HKD1_k127_6272855_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000006567 242.0
HKD1_k127_6272855_6 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000002835 240.0
HKD1_k127_6272855_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000124 213.0
HKD1_k127_6272855_8 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000003443 136.0
HKD1_k127_6272855_9 Bacterial regulatory proteins, tetR family - - - 0.000000000000007932 82.0
HKD1_k127_6280242_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.12e-290 914.0
HKD1_k127_6280242_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 480.0
HKD1_k127_6280242_10 Hydrolase K20862 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0022611,GO:0032502,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104 0.0000000000003022 83.0
HKD1_k127_6280242_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000004642 76.0
HKD1_k127_6280242_2 von Willebrand factor type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 361.0
HKD1_k127_6280242_3 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 343.0
HKD1_k127_6280242_4 PFAM von Willebrand factor type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 332.0
HKD1_k127_6280242_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001103 282.0
HKD1_k127_6280242_6 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000001091 197.0
HKD1_k127_6280242_7 - - - - 0.00000000000000000000000000002811 135.0
HKD1_k127_6280242_8 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000005705 98.0
HKD1_k127_6280967_0 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 546.0
HKD1_k127_6280967_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000003502 133.0
HKD1_k127_6280967_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000257 121.0
HKD1_k127_6280967_3 Belongs to the CDS family - - - 0.00000000000000000000000006554 114.0
HKD1_k127_6280967_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000002156 85.0
HKD1_k127_6287218_0 acyl-CoA dehydrogenase activity K00248,K00253 - 1.3.8.1,1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 486.0
HKD1_k127_6287218_1 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000003841 252.0
HKD1_k127_6287218_2 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000003905 131.0
HKD1_k127_6311243_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 373.0
HKD1_k127_6311243_1 - - - - 0.00000000000000001755 93.0
HKD1_k127_6331672_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 458.0
HKD1_k127_6331672_1 - - - - 0.0000000001377 74.0
HKD1_k127_6331672_2 methyltransferase - - - 0.0004455 46.0
HKD1_k127_6343685_0 PFAM isochorismatase hydrolase - - - 0.0000000000000000000000000000000000008692 145.0
HKD1_k127_6343685_1 Belongs to the peptidase M16 family - - - 0.000000000000000000000000001977 126.0
HKD1_k127_6343685_2 Belongs to the OMP decarboxylase family. Type 2 subfamily K00762,K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.0000000000000000000000001765 109.0
HKD1_k127_6343685_3 May be involved in the folding of the extracellular lipase during its passage through the periplasm - - - 0.00000000000000000004039 98.0
HKD1_k127_6343685_4 PQ loop repeat K15383 - - 0.000000000000000002482 96.0
HKD1_k127_6343685_5 orotate phosphoribosyltransferase activity K13421 GO:0003674,GO:0003824,GO:0004588,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.10,4.1.1.23 0.0000000004458 63.0
HKD1_k127_6351962_0 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 342.0
HKD1_k127_6351962_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000003149 249.0
HKD1_k127_6351962_2 alcohol dehydrogenase - - - 0.000003056 49.0
HKD1_k127_637401_0 TonB dependent receptor K02014,K16089 - - 0.00000000000000000000000000000000000000000000005588 192.0
HKD1_k127_637401_1 - - - - 0.000002095 56.0
HKD1_k127_6376323_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 546.0
HKD1_k127_6376323_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 486.0
HKD1_k127_6376323_2 antibiotic catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 440.0
HKD1_k127_6376323_3 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 375.0
HKD1_k127_6376323_4 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003893 283.0
HKD1_k127_6376323_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000001485 225.0
HKD1_k127_6376323_6 Pkd domain containing protein - - - 0.0000000000000000000000000000000000003371 145.0
HKD1_k127_6376323_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000008842 143.0
HKD1_k127_639607_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 1.121e-197 625.0
HKD1_k127_639607_1 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 366.0
HKD1_k127_639607_10 polysaccharide deacetylase - - - 0.00000000000000000005493 93.0
HKD1_k127_639607_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 350.0
HKD1_k127_639607_3 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006548 303.0
HKD1_k127_639607_4 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005843 293.0
HKD1_k127_639607_5 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000001673 219.0
HKD1_k127_639607_6 actin binding - - - 0.0000000000000000000000000000000078 133.0
HKD1_k127_639607_7 TIGRFAM iron-sulfur cluster binding protein - - - 0.00000000000000000000000001647 112.0
HKD1_k127_639607_8 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000001474 115.0
HKD1_k127_639607_9 - - - - 0.0000000000000000000438 103.0
HKD1_k127_6399418_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009254 396.0
HKD1_k127_6399418_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 317.0
HKD1_k127_6399418_2 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004168 274.0
HKD1_k127_6399418_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000154 155.0
HKD1_k127_6403624_0 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000001653 114.0
HKD1_k127_6403624_1 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000003755 125.0
HKD1_k127_6408436_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006707 250.0
HKD1_k127_6408436_1 Phosphate acyltransferases - - - 0.00000000000000000000000000000003061 136.0
HKD1_k127_640864_0 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 5.429e-205 646.0
HKD1_k127_640864_1 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 489.0
HKD1_k127_640864_2 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 480.0
HKD1_k127_640864_3 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 436.0
HKD1_k127_640864_4 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008721 271.0
HKD1_k127_640864_5 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000004176 179.0
HKD1_k127_640864_7 Transposase IS200 like - - - 0.0000000000000000000003467 103.0
HKD1_k127_640864_8 Protein of unknown function (DUF3047) - - - 0.0000000000000000605 90.0
HKD1_k127_6420692_0 Carboxypeptidase regulatory-like domain K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000221 252.0
HKD1_k127_6420692_1 Domain of unknown function (DUF4215) - - - 0.00000000000000000000000000000000007621 156.0
HKD1_k127_6420692_2 Polypeptide deformylase K01462 - 3.5.1.88 0.00000000000001792 81.0
HKD1_k127_6420692_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000006492 53.0
HKD1_k127_6436802_0 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 478.0
HKD1_k127_6448273_0 (ABC) transporter K15738 - - 8.076e-202 655.0
HKD1_k127_6448273_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000001276 112.0
HKD1_k127_6448273_2 3D domain - - - 0.000000000000000000000006889 108.0
HKD1_k127_6448273_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000265 58.0
HKD1_k127_6479399_0 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 609.0
HKD1_k127_6479399_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000002942 140.0
HKD1_k127_6479399_2 WHG domain - - - 0.0000000000000000000000000000004289 130.0
HKD1_k127_6479399_3 domain protein - - - 0.00000000004822 77.0
HKD1_k127_6479399_4 Trypsin-like serine protease K01315,K09752 - 3.4.21.7 0.000000007438 69.0
HKD1_k127_6479399_5 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000343 53.0
HKD1_k127_6479399_6 Zinc metalloprotease (Elastase) - - - 0.000009796 59.0
HKD1_k127_648112_0 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 406.0
HKD1_k127_648112_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000296 285.0
HKD1_k127_648112_2 electron transfer activity K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.0000000000000000000000000000000000000000000000001097 185.0
HKD1_k127_6481437_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.345e-286 901.0
HKD1_k127_6481437_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.459e-253 793.0
HKD1_k127_6481437_10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000002012 233.0
HKD1_k127_6481437_11 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000003421 204.0
HKD1_k127_6481437_12 TIGRFAM DNA binding domain protein, excisionase family K22491 - - 0.0000000000000000000000000000000000000000000000000000276 201.0
HKD1_k127_6481437_13 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000006773 184.0
HKD1_k127_6481437_14 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000001115 178.0
HKD1_k127_6481437_15 - - - - 0.000000000000000000000000000000000000000000002849 180.0
HKD1_k127_6481437_16 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000045 165.0
HKD1_k127_6481437_17 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000003195 113.0
HKD1_k127_6481437_18 peptidyl-tyrosine sulfation - - - 0.000000000000000000000007245 107.0
HKD1_k127_6481437_19 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000001087 89.0
HKD1_k127_6481437_2 Belongs to the aconitase IPM isomerase family K01703 - 4.2.1.33,4.2.1.35 1.92e-222 697.0
HKD1_k127_6481437_20 Tetratricopeptide repeat - - - 0.00000000000004829 86.0
HKD1_k127_6481437_22 Bacterial extracellular solute-binding protein K02012 - - 0.0000005152 61.0
HKD1_k127_6481437_3 PFAM aminotransferase class-III K01845,K21585 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006083,GO:0006091,GO:0006113,GO:0006520,GO:0006553,GO:0006554,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0015980,GO:0016020,GO:0016054,GO:0016740,GO:0016769,GO:0016853,GO:0016866,GO:0016869,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019475,GO:0019477,GO:0019665,GO:0019666,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044464,GO:0046148,GO:0046395,GO:0046440,GO:0046483,GO:0046501,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 2.6.1.111,5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 524.0
HKD1_k127_6481437_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 437.0
HKD1_k127_6481437_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 304.0
HKD1_k127_6481437_6 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001252 278.0
HKD1_k127_6481437_7 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002053 285.0
HKD1_k127_6481437_8 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003196 250.0
HKD1_k127_6481437_9 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000209 221.0
HKD1_k127_6486821_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 604.0
HKD1_k127_6486821_1 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 420.0
HKD1_k127_6486821_10 - - - - 0.00005475 54.0
HKD1_k127_6486821_2 Alpha/beta hydrolase family - GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003674,GO:0003824,GO:0004301,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006725,GO:0006793,GO:0006796,GO:0006950,GO:0006952,GO:0006954,GO:0007600,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0009056,GO:0009810,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0015643,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0018742,GO:0018904,GO:0019216,GO:0019218,GO:0019222,GO:0019233,GO:0019439,GO:0019752,GO:0030258,GO:0032501,GO:0032787,GO:0033559,GO:0042577,GO:0042578,GO:0042579,GO:0042592,GO:0042632,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043651,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045777,GO:0046272,GO:0046483,GO:0046839,GO:0046872,GO:0046983,GO:0048518,GO:0048878,GO:0050789,GO:0050877,GO:0050896,GO:0055088,GO:0055092,GO:0060255,GO:0062012,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090181,GO:0097176,GO:1900673,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 322.0
HKD1_k127_6486821_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 289.0
HKD1_k127_6486821_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000003502 272.0
HKD1_k127_6486821_5 Cold-shock protein K03704 - - 0.000000000000000000000000001264 112.0
HKD1_k127_6486821_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000003761 99.0
HKD1_k127_6486821_7 zinc ion binding K00859,K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 2.7.1.24 0.0000000000000000188 84.0
HKD1_k127_6486821_8 subunit of a heme lyase K02200 - - 0.00000000000000006739 96.0
HKD1_k127_6486821_9 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000004379 68.0
HKD1_k127_6510537_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 1.057e-321 1002.0
HKD1_k127_6510537_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000002686 206.0
HKD1_k127_6521882_0 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 477.0
HKD1_k127_6521882_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 422.0
HKD1_k127_6521882_10 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000009533 64.0
HKD1_k127_6521882_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00001003 59.0
HKD1_k127_6521882_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 362.0
HKD1_k127_6521882_3 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000003147 209.0
HKD1_k127_6521882_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019538,GO:0020037,GO:0030091,GO:0031224,GO:0031226,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000002127 210.0
HKD1_k127_6521882_5 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000001597 153.0
HKD1_k127_6521882_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000008427 151.0
HKD1_k127_6521882_7 endoribonuclease L-PSP - - - 0.000000000000000000000000000001699 124.0
HKD1_k127_6521882_8 Thiol-disulfide oxidoreductase - - - 0.000000000000000000000175 100.0
HKD1_k127_6521882_9 Protein of unknown function (DUF1329) - - - 0.0000000000001322 83.0
HKD1_k127_6541983_0 Acetyl-CoA acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 442.0
HKD1_k127_6541983_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 327.0
HKD1_k127_6541983_2 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 338.0
HKD1_k127_6541983_3 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000003368 222.0
HKD1_k127_6541983_4 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000001002 151.0
HKD1_k127_6541983_5 general secretion pathway protein K02246,K02456,K02457 - - 0.000000007649 66.0
HKD1_k127_6556551_0 6-phosphogluconolactonase activity - - - 5.058e-265 865.0
HKD1_k127_6556551_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002866 276.0
HKD1_k127_6556551_2 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000004357 213.0
HKD1_k127_6556551_3 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000002732 186.0
HKD1_k127_6556551_4 sterol desaturase - - - 0.0000000000000000000000000000000000000000000002059 172.0
HKD1_k127_6560703_0 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 380.0
HKD1_k127_6560703_1 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 289.0
HKD1_k127_6560703_2 (ABC) transporter K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000006371 229.0
HKD1_k127_6560703_3 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000003385 237.0
HKD1_k127_6560703_4 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000006699 156.0
HKD1_k127_6560703_5 Methyltransferase K07443 - - 0.0000000000000000000955 98.0
HKD1_k127_6560703_6 BolA family transcriptional regulator K09780 - - 0.000000000000002486 81.0
HKD1_k127_6563123_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.535e-198 640.0
HKD1_k127_6563123_1 Belongs to the ompA family - - - 0.0000000000000000000000000000000000001612 154.0
HKD1_k127_6563123_2 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000002139 143.0
HKD1_k127_6563123_3 AMP-binding enzyme - - - 0.00000000000000000000000007343 123.0
HKD1_k127_6563123_4 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000008978 112.0
HKD1_k127_6563123_5 PQQ-like domain - - - 0.000000000000000006486 100.0
HKD1_k127_6563123_6 6-phosphogluconolactonase activity - - - 0.0000000001279 63.0
HKD1_k127_6566854_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 349.0
HKD1_k127_6566854_1 GAF domain - - - 0.0000000000000000000000000000000000000000000000000005005 203.0
HKD1_k127_6566854_2 Responsible for synthesis of pseudouridine from uracil K06177,K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000001053 146.0
HKD1_k127_6566854_3 NUDIX domain - - - 0.0000000000000000000000000000000001399 141.0
HKD1_k127_6566854_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000002201 97.0
HKD1_k127_6566854_5 - - - - 0.00000000000001242 79.0
HKD1_k127_656965_0 COG0348 Polyferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 543.0
HKD1_k127_656965_1 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 349.0
HKD1_k127_656965_2 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.0000000000000000000000000000000000000000006597 158.0
HKD1_k127_656965_3 FixH K09926 - - 0.0000000000000000000000006456 111.0
HKD1_k127_656965_4 P-type atpase K01533 - 3.6.3.4 0.0000000000844 71.0
HKD1_k127_656965_5 Cbb3-type cytochrome oxidase component FixQ - - - 0.000122 50.0
HKD1_k127_6601335_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 505.0
HKD1_k127_6601335_1 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 450.0
HKD1_k127_6601335_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 350.0
HKD1_k127_6601335_3 NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 330.0
HKD1_k127_6601335_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004989 301.0
HKD1_k127_6616799_0 Alcohol dehydrogenase GroES-like domain K00121,K00148 - 1.1.1.1,1.1.1.284,1.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 289.0
HKD1_k127_6616799_1 Belongs to the GPAT DAPAT family K00631 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000002264 268.0
HKD1_k127_6616799_2 peptidyl-tyrosine sulfation - - - 0.0000000000000001189 88.0
HKD1_k127_6630171_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 506.0
HKD1_k127_6630171_1 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 515.0
HKD1_k127_6630171_10 Cytochrome C oxidase, cbb3-type, subunit III K02305 - - 0.000000000000002511 80.0
HKD1_k127_6630171_11 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.00000000000007472 80.0
HKD1_k127_6630171_12 anaerobic respiration - - - 0.0000008127 61.0
HKD1_k127_6630171_2 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 479.0
HKD1_k127_6630171_3 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 416.0
HKD1_k127_6630171_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 360.0
HKD1_k127_6630171_5 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008121 252.0
HKD1_k127_6630171_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000001831 238.0
HKD1_k127_6630171_7 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000001441 196.0
HKD1_k127_6630171_8 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000001377 129.0
HKD1_k127_6630171_9 - - - - 0.000000000000000000000000000000602 140.0
HKD1_k127_6686233_0 TIGRFAM leucyl-tRNA synthetase, eubacterial and mitochondrial family - - - 4.05e-304 946.0
HKD1_k127_6686233_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 488.0
HKD1_k127_6686233_10 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000001218 108.0
HKD1_k127_6686233_11 Acetoacetate decarboxylase (ADC) - - - 0.000000000000000000001433 111.0
HKD1_k127_6686233_12 Protein of unknown function (DUF2905) - - - 0.00000000000000000004767 91.0
HKD1_k127_6686233_13 Lipopolysaccharide-assembly - - - 0.00000000000000009208 88.0
HKD1_k127_6686233_14 Binds directly to 16S ribosomal RNA K02968 - - 0.00000001014 68.0
HKD1_k127_6686233_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 341.0
HKD1_k127_6686233_3 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 320.0
HKD1_k127_6686233_4 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000626 303.0
HKD1_k127_6686233_5 AAA ATPase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002412 279.0
HKD1_k127_6686233_6 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000004399 266.0
HKD1_k127_6686233_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000021 185.0
HKD1_k127_6686233_8 Domain of unknown function (DUF3597) - - - 0.000000000000000000000000000000000000000000004029 171.0
HKD1_k127_6686233_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000004892 138.0
HKD1_k127_6715675_0 Mannosyl oligosaccharide glucosidase - - - 3.12e-280 874.0
HKD1_k127_6715675_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000002229 196.0
HKD1_k127_6715675_2 cell redox homeostasis K02199,K03671 - - 0.00000000000000000000000000001946 123.0
HKD1_k127_6715675_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000005233 83.0
HKD1_k127_6729869_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.202e-207 670.0
HKD1_k127_6729869_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 311.0
HKD1_k127_6729869_2 thiolester hydrolase activity - - - 0.0000000000000000000000000001753 121.0
HKD1_k127_6729869_3 SnoaL-like domain - - - 0.000000000000000000000000000695 119.0
HKD1_k127_6729869_4 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000124 112.0
HKD1_k127_6729869_5 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.000000000000000000207 91.0
HKD1_k127_674046_0 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 385.0
HKD1_k127_674046_1 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 337.0
HKD1_k127_674046_2 Carbon-nitrogen hydrolase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000227 273.0
HKD1_k127_674046_3 PHB/PHA accumulation regulator DNA-binding domain - - - 0.0000000000000000000000004365 117.0
HKD1_k127_6745592_0 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000001956 226.0
HKD1_k127_6745592_1 alpha beta - - - 0.000000002478 70.0
HKD1_k127_6745592_2 Phenylacetate-CoA oxygenase - - - 0.0006388 50.0
HKD1_k127_6750826_0 Peptidase family S49 K04773,K04774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 346.0
HKD1_k127_6750826_1 - - - - 0.000456 50.0
HKD1_k127_67637_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006729 263.0
HKD1_k127_67637_1 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000002217 248.0
HKD1_k127_67637_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000002469 194.0
HKD1_k127_67637_3 - - - - 0.0000000000000000000000000000000000006534 157.0
HKD1_k127_67637_4 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000003758 113.0
HKD1_k127_6767293_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.884e-224 702.0
HKD1_k127_6767293_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 391.0
HKD1_k127_6767293_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 388.0
HKD1_k127_6767293_3 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000007135 224.0
HKD1_k127_6767293_4 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000002685 189.0
HKD1_k127_6774782_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 470.0
HKD1_k127_6774782_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 380.0
HKD1_k127_6774782_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002788 298.0
HKD1_k127_6774782_3 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000002545 242.0
HKD1_k127_6774782_4 GAF domain - - - 0.00000000000000000000000000000002288 145.0
HKD1_k127_6787146_1 - - - - 0.0000001592 62.0
HKD1_k127_6794430_0 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 368.0
HKD1_k127_6794430_1 Multicopper oxidase K04753 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 332.0
HKD1_k127_6794430_10 protein auto-ADP-ribosylation K10799 GO:0000209,GO:0000228,GO:0000242,GO:0000723,GO:0000781,GO:0000784,GO:0003674,GO:0003824,GO:0003950,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006139,GO:0006259,GO:0006464,GO:0006471,GO:0006725,GO:0006807,GO:0006996,GO:0008104,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010638,GO:0010639,GO:0010646,GO:0010647,GO:0012505,GO:0015630,GO:0016043,GO:0016567,GO:0016740,GO:0016757,GO:0016763,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0023051,GO:0023056,GO:0030111,GO:0030162,GO:0030177,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032200,GO:0032204,GO:0032205,GO:0032206,GO:0032210,GO:0032212,GO:0032268,GO:0032270,GO:0032446,GO:0032501,GO:0032502,GO:0033036,GO:0033043,GO:0033044,GO:0033365,GO:0034502,GO:0034613,GO:0034641,GO:0035264,GO:0036211,GO:0040007,GO:0040008,GO:0040014,GO:0042176,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043412,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044454,GO:0044464,GO:0045732,GO:0045862,GO:0045934,GO:0045935,GO:0046483,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048638,GO:0050789,GO:0050793,GO:0050794,GO:0051052,GO:0051053,GO:0051054,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051239,GO:0051246,GO:0051247,GO:0051276,GO:0051641,GO:0060249,GO:0060255,GO:0060828,GO:0065007,GO:0065008,GO:0070013,GO:0070198,GO:0070212,GO:0070213,GO:0070647,GO:0070727,GO:0071704,GO:0071840,GO:0080090,GO:0090263,GO:0090304,GO:0090364,GO:0097110,GO:0098687,GO:1901360,GO:1901564,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1904353,GO:1904355,GO:1904356,GO:1904357,GO:1904358,GO:2000058,GO:2000060,GO:2000112,GO:2000278,GO:2000573,GO:2001251,GO:2001252 2.4.2.30 0.000000000000000005804 93.0
HKD1_k127_6794430_2 RES - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 317.0
HKD1_k127_6794430_3 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 308.0
HKD1_k127_6794430_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009016 273.0
HKD1_k127_6794430_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000001955 247.0
HKD1_k127_6794430_7 Protein of unknown function (DUF2384) - - - 0.00000000000000000000000000000000000000000000000001184 183.0
HKD1_k127_6794430_8 GAF domain - - - 0.0000000000000000000000000000000000000000000001424 189.0
HKD1_k127_6821208_0 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 377.0
HKD1_k127_6821208_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000001668 190.0
HKD1_k127_6821208_2 carboxymuconolactone decarboxylase K07486 - - 0.00000000000000000000007215 114.0
HKD1_k127_6824107_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001785 266.0
HKD1_k127_6824107_1 PFAM Ig domain protein, group 1 domain protein - - - 0.00000000000000000000000000000000003466 158.0
HKD1_k127_6824107_2 PFAM Ig domain protein, group 1 domain protein K20276 - - 0.0000000000000000000000000102 130.0
HKD1_k127_6853090_0 PFAM Haloacid dehalogenase-like hydrolase - - - 4.125e-215 681.0
HKD1_k127_6853090_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 432.0
HKD1_k127_6853090_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000998 228.0
HKD1_k127_6855058_0 Phospholipase D. Active site motifs. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 421.0
HKD1_k127_6855058_1 Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002115 290.0
HKD1_k127_6855058_2 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000012 241.0
HKD1_k127_6855058_3 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000001209 205.0
HKD1_k127_6855058_4 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000001165 190.0
HKD1_k127_6909052_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 577.0
HKD1_k127_6909052_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18903 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 497.0
HKD1_k127_6952041_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 504.0
HKD1_k127_6952041_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 332.0
HKD1_k127_6971743_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 459.0
HKD1_k127_6971743_1 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 449.0
HKD1_k127_6971743_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 321.0
HKD1_k127_6971743_3 synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000002258 268.0
HKD1_k127_6971743_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000161 124.0
HKD1_k127_6971743_5 Patatin phospholipase K07001 - - 0.000000000000000000014 107.0
HKD1_k127_6971743_6 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation K01083,K10955 - 3.1.3.8 0.00000000007689 73.0
HKD1_k127_6986004_0 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 503.0
HKD1_k127_6988307_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 529.0
HKD1_k127_6988307_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 329.0
HKD1_k127_6988307_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000003136 259.0
HKD1_k127_6988307_3 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000002182 249.0
HKD1_k127_6988307_4 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000007469 241.0
HKD1_k127_6988307_5 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.0000000000102 70.0
HKD1_k127_700253_0 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 301.0
HKD1_k127_700253_1 Pilus assembly protein PilX - - - 0.00000000000000000000000000000000000000000000000004552 188.0
HKD1_k127_7005327_0 Aldehyde dehydrogenase family K00137 - 1.2.1.19 1.797e-220 698.0
HKD1_k127_7005327_1 Spermidine putrescine ABC transporter substrate-binding protein K02055 GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 567.0
HKD1_k127_7005327_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 426.0
HKD1_k127_7005327_3 ABC transporter (Permease K02054 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 392.0
HKD1_k127_7005327_4 ABC transporter (permease) K02053 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 369.0
HKD1_k127_7005327_5 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 316.0
HKD1_k127_7010270_0 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 454.0
HKD1_k127_7010270_1 Melibiase K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 368.0
HKD1_k127_7010270_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 302.0
HKD1_k127_7010270_3 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.0000000000000000000000000000000000005772 151.0
HKD1_k127_7010270_4 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000202 96.0
HKD1_k127_7028551_0 AcrB/AcrD/AcrF family - - - 0.0 1444.0
HKD1_k127_7028551_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 442.0
HKD1_k127_7028551_2 Aldose 1-epimerase - - - 0.000000000000000000000000000000000000000000000009085 195.0
HKD1_k127_7046647_0 P-type atpase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000001397 220.0
HKD1_k127_7046647_1 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000001568 194.0
HKD1_k127_7046647_2 - - - - 0.0000000000000000000001271 104.0
HKD1_k127_7047305_0 Belongs to the heat shock protein 70 family K04046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 360.0
HKD1_k127_7047305_1 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000006333 237.0
HKD1_k127_7049822_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 532.0
HKD1_k127_7049822_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000003523 183.0
HKD1_k127_7049822_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000202 146.0
HKD1_k127_7050585_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 4.452e-229 722.0
HKD1_k127_7050585_1 Amidohydrolase K07045 - - 4.919e-206 647.0
HKD1_k127_7050585_2 Dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 335.0
HKD1_k127_7050585_3 metal-dependent hydrolase of the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000001671 250.0
HKD1_k127_7050585_4 lipopolysaccharide transport K22110 - - 0.00000000000000000002173 92.0
HKD1_k127_7050585_5 Iron-containing redox enzyme K06137 - 1.3.3.11 0.000008248 57.0
HKD1_k127_7050724_0 TIGRFAM FeS assembly protein SufB K09014 - - 3.916e-263 816.0
HKD1_k127_7050724_1 ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 365.0
HKD1_k127_7050724_2 Uncharacterized protein family (UPF0051) K09015 - - 0.000003848 58.0
HKD1_k127_7053232_0 alcohol dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 389.0
HKD1_k127_7053232_1 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000004189 190.0
HKD1_k127_7053232_2 Amidohydrolase family - - - 0.00000000000000000001844 94.0
HKD1_k127_7068913_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.788e-195 623.0
HKD1_k127_7068913_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000006824 237.0
HKD1_k127_7068913_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000001088 181.0
HKD1_k127_7068913_3 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000009147 161.0
HKD1_k127_7068913_4 Prokaryotic N-terminal methylation motif - - - 0.00000001533 66.0
HKD1_k127_7068913_5 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00005736 46.0
HKD1_k127_7073435_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.491e-266 838.0
HKD1_k127_7073787_0 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 580.0
HKD1_k127_7073787_1 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 449.0
HKD1_k127_7086203_0 Lipase maturation factor - - - 1.433e-204 647.0
HKD1_k127_7086203_1 all-trans-retinol 13,14-reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 551.0
HKD1_k127_7086203_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 298.0
HKD1_k127_7086203_3 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001663 239.0
HKD1_k127_7086203_4 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000001116 134.0
HKD1_k127_7086203_5 Sulfatase - - - 0.0000000000000000000000001509 107.0
HKD1_k127_7093494_0 dihydrodipicolinate reductase K21672 - 1.4.1.12,1.4.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 507.0
HKD1_k127_7093494_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 333.0
HKD1_k127_7093494_2 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000007174 183.0
HKD1_k127_7096221_0 PFAM response regulator receiver K07665 - - 0.000000000000000000000000000000000000000000000000000000000000004623 223.0
HKD1_k127_7096221_1 Histidine kinase K07644 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000002931 218.0
HKD1_k127_7096221_2 - - - - 0.000000000000000000001037 105.0
HKD1_k127_7102119_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 3.001e-210 662.0
HKD1_k127_7102119_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 474.0
HKD1_k127_7116852_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 4.74e-322 1007.0
HKD1_k127_7116852_1 Translation Elongation Factor K03833 - - 0.000000000000000000000001094 110.0
HKD1_k127_7125480_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 366.0
HKD1_k127_7125480_1 Zn-dependent hydrolases of the beta-lactamase fold K13985 - 3.1.4.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 335.0
HKD1_k127_7125480_2 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 299.0
HKD1_k127_7125480_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000002297 241.0
HKD1_k127_7125480_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000002556 246.0
HKD1_k127_7125480_5 PFAM Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000381 197.0
HKD1_k127_7125480_6 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000008379 144.0
HKD1_k127_7125480_7 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000001469 117.0
HKD1_k127_7125480_8 AsmA-like C-terminal region K07289 - - 0.0005722 53.0
HKD1_k127_7127333_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001618 256.0
HKD1_k127_7127333_1 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000009133 184.0
HKD1_k127_7129119_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 546.0
HKD1_k127_7129119_1 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 432.0
HKD1_k127_7129119_2 LAO AO transport system K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006128 283.0
HKD1_k127_7129119_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000009417 243.0
HKD1_k127_7129119_4 Calcineurin-like phosphoesterase superfamily domain K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000001358 213.0
HKD1_k127_7129119_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000003897 115.0
HKD1_k127_714886_0 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 439.0
HKD1_k127_714886_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 308.0
HKD1_k127_714886_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000001536 153.0
HKD1_k127_7150476_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 346.0
HKD1_k127_7150476_1 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000003902 238.0
HKD1_k127_7150476_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000001854 187.0
HKD1_k127_7150476_3 tetratricopeptide repeat - - - 0.0000003102 57.0
HKD1_k127_7156342_0 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 638.0
HKD1_k127_7156342_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 366.0
HKD1_k127_7156342_2 DNA repair protein K03919 - 1.14.11.33 0.00000000000000000000000000000000000000000000000000000000000000000000004008 246.0
HKD1_k127_7156342_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000002271 228.0
HKD1_k127_7156342_4 NHL repeat - - - 0.000000000000000000000000000000000000000000000002407 201.0
HKD1_k127_7156342_5 YCII-related domain - - - 0.0000000000000000000000000000000000000000008163 165.0
HKD1_k127_7156342_6 Methyltransferase domain - - - 0.000000000000000000000000000000000004822 156.0
HKD1_k127_7162007_0 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000004884 253.0
HKD1_k127_7162007_1 haemagglutination activity domain - - - 0.0001203 55.0
HKD1_k127_7164728_0 Belongs to the transketolase family K00615 - 2.2.1.1 0.0 1021.0
HKD1_k127_7164728_1 Belongs to the GPI family K01810 - 5.3.1.9 4.802e-261 849.0
HKD1_k127_7164728_2 dioxygenase K11159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 520.0
HKD1_k127_7164728_3 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 515.0
HKD1_k127_7164728_4 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000003939 169.0
HKD1_k127_7164728_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000008122 163.0
HKD1_k127_7185888_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 413.0
HKD1_k127_7185888_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 340.0
HKD1_k127_7185888_2 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000001871 222.0
HKD1_k127_7185888_3 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.00000000000000000000000000000000001421 144.0
HKD1_k127_7185888_4 Smr domain - - - 0.000000000000004739 80.0
HKD1_k127_7185888_5 Integrin alpha (beta-propellor repeats). - - - 0.00005745 53.0
HKD1_k127_7187438_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 8.286e-284 914.0
HKD1_k127_7187438_1 DEAD DEAH box helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 614.0
HKD1_k127_7187438_2 Extradiol ring-cleavage dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 328.0
HKD1_k127_7187438_3 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000005987 246.0
HKD1_k127_7187438_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000001477 123.0
HKD1_k127_7193001_0 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 388.0
HKD1_k127_7193001_1 helix_turn_helix, Lux Regulon - - - 0.000000004767 65.0
HKD1_k127_7204307_0 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 350.0
HKD1_k127_7204307_1 Glycosyl transferase family 21 K03669 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006073,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009628,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016740,GO:0016757,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051273,GO:0051274,GO:0071704,GO:0071944,GO:1901576 - 0.00000000000000000000000000000000000000000001211 184.0
HKD1_k127_7209900_0 PIN domain K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 578.0
HKD1_k127_7209900_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 520.0
HKD1_k127_7209900_2 Ecdysteroid kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 484.0
HKD1_k127_7209900_3 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 311.0
HKD1_k127_7209900_4 PhoD-like phosphatase K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000001785 273.0
HKD1_k127_7209900_5 AIG2-like family - - - 0.000000000000000000000000295 111.0
HKD1_k127_7209900_6 sequence-specific DNA binding - - - 0.000005418 57.0
HKD1_k127_7212865_0 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 324.0
HKD1_k127_7212865_1 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008717 256.0
HKD1_k127_7212865_2 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000003152 199.0
HKD1_k127_7212865_3 Protein of unknown function, DUF547 - - - 0.00000000000000000000002889 116.0
HKD1_k127_7212865_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000004999 78.0
HKD1_k127_723628_0 photoreceptor activity - - - 0.00000000000000000000000000000000000000000000000006183 196.0
HKD1_k127_723628_1 response regulator, receiver K00384,K07315 - 1.8.1.9,3.1.3.3 0.0000000000000000000000000000000000000002285 167.0
HKD1_k127_723628_2 Response regulator, receiver - - - 0.0000000000000000000000000000000000003241 146.0
HKD1_k127_723628_3 - - - - 0.00000000000000000000000009 108.0
HKD1_k127_7240725_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 575.0
HKD1_k127_7240725_1 ATPase associated with K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 337.0
HKD1_k127_7240725_2 Putative glutamine amidotransferase K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000541 310.0
HKD1_k127_7240725_3 Von Willebrand factor type A - - - 0.00000000000000000000000000000000794 140.0
HKD1_k127_7240725_4 - - - - 0.00000000000000000001369 95.0
HKD1_k127_7240725_5 PFAM von Willebrand factor type A - - - 0.000000000000000003877 100.0
HKD1_k127_7240725_7 Thioesterase superfamily - - - 0.000000000000002558 87.0
HKD1_k127_7241333_0 histidine kinase, HAMP K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 542.0
HKD1_k127_7241333_1 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 419.0
HKD1_k127_7241333_2 AAA ATPase domain - - - 0.000000000000000000000000000000001452 145.0
HKD1_k127_7241333_3 cyclopropane-fatty-acyl-phospholipid synthase K20444 - - 0.00000000000000000000000000001005 137.0
HKD1_k127_7241333_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000006846 66.0
HKD1_k127_7241333_5 pathogenesis - - - 0.0000000005382 72.0
HKD1_k127_7255141_0 Belongs to the ClpA ClpB family K03694 - - 4.838e-246 773.0
HKD1_k127_7255141_1 oxidoreductases (related to aryl-alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 464.0
HKD1_k127_7255141_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000005888 126.0
HKD1_k127_7267620_0 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 390.0
HKD1_k127_7267620_1 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004006 260.0
HKD1_k127_7272968_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 486.0
HKD1_k127_7272968_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072 - 3.6.3.31 0.0000000000000000000000000000000000000009004 158.0
HKD1_k127_7272968_3 Outer membrane efflux protein - - - 0.0000000000008865 76.0
HKD1_k127_7289010_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 476.0
HKD1_k127_7289010_1 PFAM ABC transporter related K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 318.0
HKD1_k127_7289010_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001592 271.0
HKD1_k127_7289010_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002056 267.0
HKD1_k127_7289010_4 phosphatidylcholine synthase K01004 - 2.7.8.24 0.000000000000000000000000000000000000000000000000000000000382 216.0
HKD1_k127_7289010_5 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000006859 164.0
HKD1_k127_7289010_6 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000689 118.0
HKD1_k127_7289010_7 protein conserved in bacteria K09774 - - 0.000000001461 67.0
HKD1_k127_7315165_0 Pyridine nucleotide-disulphide oxidoreductase - - - 3.281e-211 670.0
HKD1_k127_7315165_1 DNA photolyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 416.0
HKD1_k127_7315165_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000001464 201.0
HKD1_k127_7315165_3 Luciferase-like monooxygenase - - - 0.000000000000000000001603 97.0
HKD1_k127_7315165_4 Dodecin K09165 - - 0.000003976 53.0
HKD1_k127_7319720_0 DEAD DEAH box helicase K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 317.0
HKD1_k127_7319720_1 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000005222 244.0
HKD1_k127_7322616_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 391.0
HKD1_k127_7322616_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis - - - 0.000000000000000000000000000000000000000000000000000000000654 210.0
HKD1_k127_7322616_2 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000002498 173.0
HKD1_k127_7322616_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.000004785 48.0
HKD1_k127_7328131_0 Alpha-amylase domain K01182,K01187,K01226 - 3.2.1.10,3.2.1.20,3.2.1.93 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 511.0
HKD1_k127_7328131_1 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 370.0
HKD1_k127_7328131_2 PFAM Uncharacterised protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000001076 204.0
HKD1_k127_7328131_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000001998 134.0
HKD1_k127_7328131_4 domain protein - - - 0.0000000000000000000000000003829 127.0
HKD1_k127_7333284_0 Amylo-alpha-1,6-glucosidase - - - 1.93e-256 807.0
HKD1_k127_7333284_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 3.072e-244 781.0
HKD1_k127_7333284_10 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000002433 179.0
HKD1_k127_7333284_11 Permease of the major facilitator superfamily K08369 - - 0.000000000000000000000000000000000002364 156.0
HKD1_k127_7333284_12 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000006083 153.0
HKD1_k127_7333284_13 - - - - 0.0000000000000000000000000308 112.0
HKD1_k127_7333284_14 Psort location CytoplasmicMembrane, score K02237 - - 0.0000000000000000002128 93.0
HKD1_k127_7333284_15 domain, Protein K00703,K07082 - 2.4.1.21 0.0000000000000001869 85.0
HKD1_k127_7333284_16 Protein of unknown function (DUF1232) - - - 0.00000000000001519 80.0
HKD1_k127_7333284_17 Protein of unknown function (DUF692) K09930 - - 0.0000000000004816 79.0
HKD1_k127_7333284_18 Multidrug resistance protein MdtG - - - 0.000000000001275 75.0
HKD1_k127_7333284_19 Putative zinc-finger - - - 0.00000000127 63.0
HKD1_k127_7333284_2 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 4.468e-199 633.0
HKD1_k127_7333284_20 - - - - 0.00000003203 61.0
HKD1_k127_7333284_21 Sh3 type 3 domain protein - - - 0.000001047 62.0
HKD1_k127_7333284_3 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 584.0
HKD1_k127_7333284_4 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 348.0
HKD1_k127_7333284_5 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 346.0
HKD1_k127_7333284_6 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003726 295.0
HKD1_k127_7333284_7 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000000005356 270.0
HKD1_k127_7333284_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000002998 250.0
HKD1_k127_7333284_9 PFAM NAD-dependent epimerase dehydratase K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000001338 232.0
HKD1_k127_7335594_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 574.0
HKD1_k127_7335594_1 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 366.0
HKD1_k127_7335594_2 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 349.0
HKD1_k127_7335594_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 339.0
HKD1_k127_7335594_4 ADP-glyceromanno-heptose 6-epimerase activity K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 299.0
HKD1_k127_7335594_5 PFAM diacylglycerol kinase catalytic region - - - 0.000000000000000000000000000000000000000000000006808 184.0
HKD1_k127_7335594_6 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000000000000000008742 141.0
HKD1_k127_7351128_0 Sortilin, neurotensin receptor 3, - - - 3.597e-289 898.0
HKD1_k127_7354030_0 PFAM Bacterial domain of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 600.0
HKD1_k127_7355123_0 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 386.0
HKD1_k127_7355123_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000004514 187.0
HKD1_k127_7355123_2 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000899 174.0
HKD1_k127_7355123_3 alpha/beta hydrolase fold - - - 0.00000000000000000000000001485 121.0
HKD1_k127_7364344_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 490.0
HKD1_k127_7364344_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 411.0
HKD1_k127_7364344_2 Domain of unknown function (DUF4301) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009089 408.0
HKD1_k127_7364344_3 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000005802 233.0
HKD1_k127_7365962_0 Belongs to the ABC transporter superfamily K13896 - - 1.295e-213 688.0
HKD1_k127_7366148_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000625 179.0
HKD1_k127_7366148_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000004153 111.0
HKD1_k127_7366148_2 positive regulation of macromolecule biosynthetic process K03973 - - 0.00000000000000000001877 94.0
HKD1_k127_7366148_3 PspC domain - - - 0.0007364 48.0
HKD1_k127_7372984_0 Protein export membrane protein K03296,K18138 - - 0.0 1189.0
HKD1_k127_7372984_1 sulphate transporter - - - 3.699e-229 725.0
HKD1_k127_7372984_2 Aldehyde dehydrogenase family K00128 - 1.2.1.3 3.809e-217 683.0
HKD1_k127_7372984_3 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 346.0
HKD1_k127_7372984_4 Acetyltransferase (GNAT) family - - - 0.0000000000000009001 77.0
HKD1_k127_7386250_0 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 608.0
HKD1_k127_7386250_1 PFAM Glycoside hydrolase, family 38 K01191,K15524 - 3.2.1.170,3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 426.0
HKD1_k127_7386250_2 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001007 279.0
HKD1_k127_7386250_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03087 - - 0.0000000000000000000000000000000000000001756 173.0
HKD1_k127_7386250_4 nucleotidyltransferase activity - - - 0.0000000000000000000002272 104.0
HKD1_k127_7391456_0 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 488.0
HKD1_k127_7391456_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 479.0
HKD1_k127_7391456_2 Transposase K07491 - - 0.00000000000000000000000000000000000000000001906 165.0
HKD1_k127_7391456_3 CBS domain K04767,K07168,K07182 - - 0.00000000000000000000000000000001849 132.0
HKD1_k127_7391456_4 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolase - - - 0.000000000000000000000001792 114.0
HKD1_k127_7391456_5 peptidyl-prolyl cis-trans isomerase activity K03769,K03770 - 5.2.1.8 0.000000000000000000003736 106.0
HKD1_k127_7394614_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1184.0
HKD1_k127_7394614_1 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 390.0
HKD1_k127_7394614_2 Outer membrane lipoprotein-sorting protein - - - 0.000001891 55.0
HKD1_k127_7396912_0 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 336.0
HKD1_k127_7396912_1 response regulator K02479 - - 0.00000000000000000000000000007027 128.0
HKD1_k127_742417_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 7.194e-262 815.0
HKD1_k127_742417_1 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 287.0
HKD1_k127_742417_2 phosphorelay signal transduction system - - - 0.000000000000000000001655 109.0
HKD1_k127_742417_3 COG0457 FOG TPR repeat - - - 0.000000004756 66.0
HKD1_k127_7424309_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 638.0
HKD1_k127_7424309_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 330.0
HKD1_k127_7424309_2 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000001089 194.0
HKD1_k127_7424309_3 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000003601 204.0
HKD1_k127_7424309_4 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000009344 184.0
HKD1_k127_7424309_5 Transcriptional regulator K13640 - - 0.0002001 48.0
HKD1_k127_7424360_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005989 277.0
HKD1_k127_7424360_1 Sulfatase - - - 0.000000000000000000000000000000000000000000006431 184.0
HKD1_k127_7431551_0 Protein of unknown function, DUF255 K06888 - - 9.326e-200 637.0
HKD1_k127_7432847_0 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 343.0
HKD1_k127_7432847_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001338 286.0
HKD1_k127_7432847_2 transport system involved in gliding motility, auxiliary K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000001291 256.0
HKD1_k127_7432847_3 A G-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000008481 217.0
HKD1_k127_7432847_4 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000004959 218.0
HKD1_k127_7432847_5 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000001708 188.0
HKD1_k127_7432847_6 - - - - 0.00000000000000000001154 98.0
HKD1_k127_7432847_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.0000000000000000000514 96.0
HKD1_k127_7432847_8 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.000000001663 70.0
HKD1_k127_7432847_9 ATPase activity K01990,K09697 - 3.6.3.7 0.0000001244 57.0
HKD1_k127_7433173_0 cytochrome p450 - GO:0003674,GO:0003824,GO:0004497,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0046164,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 561.0
HKD1_k127_7433173_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 550.0
HKD1_k127_7433173_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 323.0
HKD1_k127_7433173_3 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000006476 187.0
HKD1_k127_7433173_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000006522 103.0
HKD1_k127_7433173_5 - - - - 0.00000000001573 67.0
HKD1_k127_7437204_0 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 494.0
HKD1_k127_7437204_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 439.0
HKD1_k127_7437204_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001337 274.0
HKD1_k127_7437204_3 PFAM Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000002152 131.0
HKD1_k127_7440627_0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 434.0
HKD1_k127_7440627_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 346.0
HKD1_k127_7440627_10 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0001514 48.0
HKD1_k127_7440627_2 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 338.0
HKD1_k127_7440627_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 306.0
HKD1_k127_7440627_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000002068 228.0
HKD1_k127_7440627_5 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000002001 175.0
HKD1_k127_7440627_6 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000003729 155.0
HKD1_k127_7440627_7 Alpha/beta hydrolase family - - - 0.00000000000000000000000006066 116.0
HKD1_k127_7440627_8 Histidine kinase - - - 0.000000001492 58.0
HKD1_k127_7449916_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 413.0
HKD1_k127_7449916_1 Sulfatase K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 335.0
HKD1_k127_7449916_2 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.0000002238 53.0
HKD1_k127_7451081_0 PFAM Radical SAM K11779 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 389.0
HKD1_k127_7451081_1 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 317.0
HKD1_k127_7451081_2 synthase K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000801 232.0
HKD1_k127_7456546_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 536.0
HKD1_k127_7456546_1 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000263 239.0
HKD1_k127_7467313_0 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000001438 69.0
HKD1_k127_7474687_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 7.141e-246 766.0
HKD1_k127_7474687_1 P-type ATPase K01533 - 3.6.3.4 2.384e-223 718.0
HKD1_k127_7474687_10 Cbb3-type cytochrome oxidase K00407 - - 0.000002601 59.0
HKD1_k127_7474687_2 COG0348 Polyferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 529.0
HKD1_k127_7474687_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 336.0
HKD1_k127_7474687_4 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 289.0
HKD1_k127_7474687_5 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000001322 198.0
HKD1_k127_7474687_6 FixH K09926 - - 0.00000000000000000000000002466 114.0
HKD1_k127_7474687_7 Acyl-CoA dehydrogenase, N-terminal domain K00248 - 1.3.8.1 0.00000000000000000000006714 99.0
HKD1_k127_7474687_8 N-terminal half of MaoC dehydratase - - - 0.000000000000000001035 88.0
HKD1_k127_7474687_9 Cytochrome oxidase maturation protein - - - 0.000000003768 69.0
HKD1_k127_7494358_0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 461.0
HKD1_k127_7494358_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 324.0
HKD1_k127_7494358_2 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 321.0
HKD1_k127_7494358_3 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000005076 248.0
HKD1_k127_7494358_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000001559 143.0
HKD1_k127_7510306_0 ATP ADP translocase K03301 - - 0.00000000000000000000000000003198 132.0
HKD1_k127_7510306_1 Diguanylate cyclase - - - 0.0000000000000000000000000006493 127.0
HKD1_k127_7510306_2 ATP:ADP antiporter activity K03301 - - 0.00000000000000000000000001232 127.0
HKD1_k127_7510306_3 ABC transporter transmembrane region K06147 - - 0.000000000000000000009335 94.0
HKD1_k127_7517133_0 His Kinase A (phosphoacceptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 625.0
HKD1_k127_7517133_1 calcium- and calmodulin-responsive adenylate cyclase activity K01406 - 3.4.24.40 0.0000000000007043 80.0
HKD1_k127_7517133_2 Metallo-peptidase family M12B Reprolysin-like - - - 0.0000000001016 71.0
HKD1_k127_7517133_3 metalloendopeptidase activity K06261,K08867,K09187,K14972,K20371 - 2.1.1.43,2.7.11.1 0.00000008123 64.0
HKD1_k127_7517133_4 - - - - 0.0000001361 61.0
HKD1_k127_7520704_0 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000001639 221.0
HKD1_k127_7520704_1 4Fe-4S single cluster domain - - - 0.0000004618 53.0
HKD1_k127_7526496_0 transmembrane transporter activity K03296 - - 1.45e-224 731.0
HKD1_k127_7526496_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 8.062e-222 713.0
HKD1_k127_7526496_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000002158 126.0
HKD1_k127_7526496_11 subunit (C K02119 - - 0.00000000000000000000000000009351 130.0
HKD1_k127_7526496_12 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.000000000000000000000115 103.0
HKD1_k127_7526496_13 - - - - 0.0000000000000000000006068 104.0
HKD1_k127_7526496_14 Biotin-lipoyl like - - - 0.000000000000000001706 97.0
HKD1_k127_7526496_16 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000001028 74.0
HKD1_k127_7526496_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000001794 65.0
HKD1_k127_7526496_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0004635 51.0
HKD1_k127_7526496_2 ATP hydrolysis coupled proton transport K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 406.0
HKD1_k127_7526496_3 S1, RNA binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002755 308.0
HKD1_k127_7526496_4 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003857 274.0
HKD1_k127_7526496_5 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000742 243.0
HKD1_k127_7526496_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000004023 239.0
HKD1_k127_7526496_7 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000008356 216.0
HKD1_k127_7526496_8 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000006955 192.0
HKD1_k127_7526496_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000003508 188.0
HKD1_k127_7530216_0 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 444.0
HKD1_k127_7530216_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 429.0
HKD1_k127_7530216_2 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 380.0
HKD1_k127_7530216_3 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001551 256.0
HKD1_k127_7530216_4 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000001793 222.0
HKD1_k127_7530216_5 Ketosteroid isomerase-related protein - - - 0.000004691 55.0
HKD1_k127_7560783_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000004127 205.0
HKD1_k127_7560783_1 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00146 - 1.2.1.3,1.2.1.39,1.2.1.8 0.0000000000000000000000000000000000000000000000000000001152 198.0
HKD1_k127_7560783_2 PAS domain K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000001669 222.0
HKD1_k127_7560783_3 - - - - 0.00000000000000000002157 106.0
HKD1_k127_7563401_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 417.0
HKD1_k127_7563401_1 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 375.0
HKD1_k127_7563401_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 296.0
HKD1_k127_7563401_3 PFAM Amidohydrolase family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000001157 253.0
HKD1_k127_7563401_4 Smr domain - - - 0.00000000000000000000000000000000000000000000000000000863 198.0
HKD1_k127_7563401_5 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.0000000000000000000000000000000000000000000001618 173.0
HKD1_k127_7563401_6 Enoyl-CoA hydratase/isomerase - - - 0.0000000000006027 71.0
HKD1_k127_7563401_7 ErfK YbiS YcfS YnhG family protein - - - 0.0001123 48.0
HKD1_k127_7572598_0 COG4257 Streptogramin lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 371.0
HKD1_k127_7572598_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000001935 157.0
HKD1_k127_7589595_0 acyl-CoA dehydrogenase K06446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 358.0
HKD1_k127_7589595_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 302.0
HKD1_k127_7589595_2 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000004406 193.0
HKD1_k127_7589595_3 - - - - 0.00000000000000000000000000000000000000000000000003512 190.0
HKD1_k127_7589595_4 all-trans-retinol 13,14-reductase activity K00231,K00514,K02293,K09879,K21677 - 1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6 0.000000000000000000000000002827 126.0
HKD1_k127_7622744_0 Belongs to the glycosyl hydrolase 31 family - - - 0.0000000000000000009187 96.0
HKD1_k127_7622744_1 metalloendoproteinase 1-like K01402 - 3.4.24.34 0.000005344 60.0
HKD1_k127_7638101_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 389.0
HKD1_k127_7638101_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003005 252.0
HKD1_k127_7638101_2 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000003226 213.0
HKD1_k127_7666134_0 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 421.0
HKD1_k127_7666134_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003727 250.0
HKD1_k127_7666134_2 SNARE associated Golgi protein - - - 0.00000000000000000000000002161 119.0
HKD1_k127_7666134_4 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000000003911 67.0
HKD1_k127_7666134_5 metallocarboxypeptidase activity K00368,K22348,K22349 - 1.16.3.3,1.7.2.1 0.000144 54.0
HKD1_k127_766943_0 Amidase K01457 - 3.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 364.0
HKD1_k127_766943_1 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000197 113.0
HKD1_k127_7688749_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000002834 237.0
HKD1_k127_7688749_1 PFAM periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000001259 207.0
HKD1_k127_7688749_2 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000001541 204.0
HKD1_k127_7688749_3 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000000000000000001201 182.0
HKD1_k127_7688749_4 TIGRFAM geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.00000000000000000000000000000000000000000005526 177.0
HKD1_k127_7688749_5 response regulator K07713 - - 0.0000000000000000000000000000000000003898 157.0
HKD1_k127_7688749_6 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000002525 109.0
HKD1_k127_7688749_7 - - - - 0.000000000000000000000001566 106.0
HKD1_k127_7688749_9 PFAM transport-associated K04065 - - 0.000003766 56.0
HKD1_k127_7697738_0 SMART Elongator protein 3 MiaB NifB - - - 1.483e-207 674.0
HKD1_k127_7697738_1 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 472.0
HKD1_k127_7697738_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000006421 233.0
HKD1_k127_7697738_3 Sulfotransferase family - - - 0.0000000000000000000000000000000000009195 149.0
HKD1_k127_7697738_4 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000003024 130.0
HKD1_k127_7726062_0 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 471.0
HKD1_k127_7726062_1 Nitroreductase family - - - 0.000000000000000000000000000000003567 144.0
HKD1_k127_7726062_2 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000007041 108.0
HKD1_k127_7735196_0 extracellular alpha-helical protein K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 610.0
HKD1_k127_7735196_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000004823 187.0
HKD1_k127_7740678_0 Extracellular solute-binding protein, family 5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 520.0
HKD1_k127_7740678_1 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 320.0
HKD1_k127_7740678_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 291.0
HKD1_k127_7740678_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000002928 128.0
HKD1_k127_7740678_4 AMP binding - - - 0.0000000000006747 83.0
HKD1_k127_7745797_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 564.0
HKD1_k127_7745797_1 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 354.0
HKD1_k127_7745797_2 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000002782 254.0
HKD1_k127_7745797_3 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000001612 241.0
HKD1_k127_7745797_4 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000005966 248.0
HKD1_k127_7745797_5 - - - - 0.0000000000000000000000004422 121.0
HKD1_k127_7745797_6 - - - - 0.00004244 54.0
HKD1_k127_7745797_7 - - - - 0.00004995 55.0
HKD1_k127_7783649_0 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 566.0
HKD1_k127_7783649_1 Horizontally Transferred TransMembrane Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 434.0
HKD1_k127_7783649_2 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 339.0
HKD1_k127_7783649_3 Imelysin K07231 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 324.0
HKD1_k127_7783649_4 Imelysin K07338 - - 0.0000000000000000000000000000000000000000000000000007825 200.0
HKD1_k127_7783649_5 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000003706 143.0
HKD1_k127_7794276_0 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 389.0
HKD1_k127_7794276_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 344.0
HKD1_k127_7794276_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003031 301.0
HKD1_k127_7796959_0 succinylglutamate desuccinylase K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 466.0
HKD1_k127_7796959_1 Desuccinylase aspartoacylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 345.0
HKD1_k127_7796959_2 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 340.0
HKD1_k127_7796959_3 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 323.0
HKD1_k127_7796959_4 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 319.0
HKD1_k127_7796959_5 Bacterial transglutaminase-like N-terminal - - - 0.00000000000000000000000000000000000000000000000000000001475 221.0
HKD1_k127_7796959_6 DTW K05812 - - 0.0000000000000000000000000000005129 131.0
HKD1_k127_7796959_7 RNA recognition motif - - - 0.0000000000000000000002218 107.0
HKD1_k127_779788_0 And related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 326.0
HKD1_k127_779788_1 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C K06137 - 1.3.3.11 0.000000000001613 80.0
HKD1_k127_779788_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0005538 45.0
HKD1_k127_7805666_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 544.0
HKD1_k127_7805666_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 520.0
HKD1_k127_7805666_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 374.0
HKD1_k127_7805666_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 301.0
HKD1_k127_7805666_4 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003461 287.0
HKD1_k127_7805666_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000006123 193.0
HKD1_k127_7805666_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000112 175.0
HKD1_k127_7805666_7 ThiS family K03154 - - 0.0000000000000001211 81.0
HKD1_k127_7809966_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 597.0
HKD1_k127_7809966_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 331.0
HKD1_k127_7809966_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 314.0
HKD1_k127_7809966_3 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 302.0
HKD1_k127_7809966_4 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001513 271.0
HKD1_k127_7809966_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000004633 209.0
HKD1_k127_7809966_6 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000002024 200.0
HKD1_k127_7809966_7 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000001852 176.0
HKD1_k127_7809966_8 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000000000009824 124.0
HKD1_k127_7812703_0 HpcH/HpaI aldolase/citrate lyase family K08691 - 4.1.3.24,4.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 568.0
HKD1_k127_7812703_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000003546 171.0
HKD1_k127_7812703_2 Belongs to the peptidase S8 family - - - 0.0000009485 55.0
HKD1_k127_7831927_0 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 416.0
HKD1_k127_7831927_1 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000006189 169.0
HKD1_k127_7831927_2 - - - - 0.0000003116 53.0
HKD1_k127_7832584_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 564.0
HKD1_k127_7832584_1 Acetyl-CoA hydrolase/transferase C-terminal domain K18288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 439.0
HKD1_k127_7832584_2 response to heat K07090 - - 0.00000000000000000000000000003108 123.0
HKD1_k127_7832584_3 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.0000000000000000000000000003317 114.0
HKD1_k127_7832584_4 acetyltransferase - - - 0.00000000000000000001545 105.0
HKD1_k127_7832584_5 SnoaL-like domain K06893 - - 0.0000000000000000002075 102.0
HKD1_k127_7832584_6 O-methyltransferase - - - 0.000002679 51.0
HKD1_k127_7850731_0 COG2124 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 446.0
HKD1_k127_7850731_1 glutathione transferase activity K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000001594 224.0
HKD1_k127_7850731_2 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000001319 200.0
HKD1_k127_7850731_3 alpha/beta hydrolase fold - - - 0.000000000000005151 75.0
HKD1_k127_7850731_4 nuclease activity - - - 0.000000000000287 75.0
HKD1_k127_7890481_0 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000006766 198.0
HKD1_k127_7890481_1 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000398 90.0
HKD1_k127_7896685_0 Bacterial regulatory protein, Fis family K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 508.0
HKD1_k127_7896685_1 PFAM Type II secretion system protein E K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 415.0
HKD1_k127_7896685_2 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 346.0
HKD1_k127_7896685_3 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005053 263.0
HKD1_k127_7896685_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000005409 208.0
HKD1_k127_790003_0 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 401.0
HKD1_k127_790003_1 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 363.0
HKD1_k127_790003_2 histidine kinase HAMP region domain protein K03406,K07216 - - 0.0000000000000000001155 102.0
HKD1_k127_790003_3 Protein of unknown function (DUF1232) - - - 0.000000000001562 81.0
HKD1_k127_790003_4 Two component signalling adaptor domain K03408 - - 0.000001693 57.0
HKD1_k127_790003_5 ABC-type branched-chain amino acid transport K07121 - - 0.000003979 59.0
HKD1_k127_7900822_0 heme binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 450.0
HKD1_k127_7900822_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000331 181.0
HKD1_k127_7911278_0 Coenzyme A transferase K01027,K01029,K01032 - 2.8.3.5,2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 391.0
HKD1_k127_7911278_1 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000002057 149.0
HKD1_k127_7920658_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 456.0
HKD1_k127_7920658_1 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 406.0
HKD1_k127_7920658_2 Helix-turn-helix domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 394.0
HKD1_k127_7920658_3 Protein of unknown function (DUF2855) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 357.0
HKD1_k127_7920658_4 Rnd family efflux transporter mfp subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 313.0
HKD1_k127_794847_0 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000149 286.0
HKD1_k127_794847_1 Cobalt transport protein K16785 - - 0.000000000000000000000000000000000000000000004534 173.0
HKD1_k127_794847_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000001607 115.0
HKD1_k127_7978261_0 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 329.0
HKD1_k127_7978261_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000001807 134.0
HKD1_k127_8009829_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 610.0
HKD1_k127_8009829_1 synthetase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 445.0
HKD1_k127_8009829_2 COG0657 Esterase lipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 375.0
HKD1_k127_8009829_3 cytochrome p450 K17474 - 1.14.15.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 342.0
HKD1_k127_8009829_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 300.0
HKD1_k127_8009829_5 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000001388 236.0
HKD1_k127_8009829_6 KR domain - - - 0.000000000000000000000000000000000000000000000000002513 201.0
HKD1_k127_8009829_7 transcriptional regulator - - - 0.0000000000000000000000000004232 123.0
HKD1_k127_8009829_8 Belongs to the peptidase S8 family - - - 0.00000000001541 78.0
HKD1_k127_8036420_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 604.0
HKD1_k127_8036420_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 308.0
HKD1_k127_8036420_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001151 256.0
HKD1_k127_8036420_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000001887 108.0
HKD1_k127_8036420_4 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000008672 117.0
HKD1_k127_8036420_5 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000004143 83.0
HKD1_k127_8036420_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000976 71.0
HKD1_k127_849278_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 351.0
HKD1_k127_849278_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000003034 199.0
HKD1_k127_849278_2 Belongs to the UDP-glycosyltransferase family - - - 0.00000000000000000000000000000000000000000000001468 188.0
HKD1_k127_849278_3 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000008691 114.0
HKD1_k127_849278_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000005593 88.0
HKD1_k127_90670_0 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 448.0
HKD1_k127_90670_1 cellulose binding - - - 0.0000001455 63.0
HKD1_k127_911406_0 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000002128 222.0
HKD1_k127_911406_1 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000001273 182.0
HKD1_k127_911406_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000001754 188.0
HKD1_k127_911406_3 Acetyltransferase (GNAT) domain K03824 - - 0.00000000000000000000000000000000000000000339 166.0
HKD1_k127_911406_4 Transcriptional - - - 0.000000000000000000000000000000000000009912 147.0
HKD1_k127_911406_5 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000221 74.0
HKD1_k127_94469_0 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 342.0
HKD1_k127_94469_1 CrtC N-terminal lipocalin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001126 259.0
HKD1_k127_953855_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 328.0
HKD1_k127_953855_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009985 313.0
HKD1_k127_967983_0 SMART Signal transduction response regulator, receiver region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 602.0
HKD1_k127_967983_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 394.0
HKD1_k127_967983_2 E-Z type HEAT repeats - - - 0.000008866 56.0
HKD1_k127_968656_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 608.0
HKD1_k127_968656_1 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 370.0
HKD1_k127_968656_10 Thioredoxin K05838 - - 0.00000000000000009178 84.0
HKD1_k127_968656_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 331.0
HKD1_k127_968656_3 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 305.0
HKD1_k127_968656_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002357 280.0
HKD1_k127_968656_5 COG2513 PEP phosphonomutase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002213 257.0
HKD1_k127_968656_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000007842 225.0
HKD1_k127_968656_7 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000009523 166.0
HKD1_k127_968656_8 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000001475 153.0
HKD1_k127_968656_9 thiolester hydrolase activity - - - 0.00000000000000001767 97.0
HKD1_k127_983898_0 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 462.0
HKD1_k127_983898_1 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 337.0