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Overview

ID MAG01709
Name HKD1_bin.21
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order Thermoanaerobaculales
Family Thermoanaerobaculaceae
Genus RBG-13-68-16
Species
Assembly information
Completeness (%) 95.45
Contamination (%) 0.82
GC content (%) 68.0
N50 (bp) 16,179
Genome size (bp) 2,915,616

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2454

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1002467_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 518.0
HKD1_k127_1002467_1 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006291 246.0
HKD1_k127_1002467_2 Domain of Unknown Function (DUF1259) - - - 0.00006219 47.0
HKD1_k127_1010092_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 339.0
HKD1_k127_1010092_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000001176 244.0
HKD1_k127_1010092_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000004048 239.0
HKD1_k127_1010092_3 Beta-eliminating lyase K01667 - 4.1.99.1 0.0000000000000000000000000000000000000000000000000000000000004168 218.0
HKD1_k127_1010092_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.0000000000000002096 83.0
HKD1_k127_1012162_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.892e-260 817.0
HKD1_k127_1012162_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 295.0
HKD1_k127_1012162_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000004218 239.0
HKD1_k127_1012162_3 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000008737 209.0
HKD1_k127_1012162_4 - - - - 0.00000009118 64.0
HKD1_k127_1017677_0 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 347.0
HKD1_k127_1017677_1 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 344.0
HKD1_k127_1017677_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003205 268.0
HKD1_k127_1017677_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000003667 260.0
HKD1_k127_1017677_4 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000028 229.0
HKD1_k127_1017677_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000002446 199.0
HKD1_k127_1017677_6 PspC domain K03973 - - 0.0000000001387 68.0
HKD1_k127_1027757_0 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 499.0
HKD1_k127_1027757_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 374.0
HKD1_k127_1027757_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 381.0
HKD1_k127_1027757_3 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001221 260.0
HKD1_k127_1048605_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 375.0
HKD1_k127_1048605_1 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001118 276.0
HKD1_k127_1048605_2 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007473 240.0
HKD1_k127_1048605_3 - - - - 0.0000000000000000000000000000000000000000004452 165.0
HKD1_k127_1048605_4 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000002225 158.0
HKD1_k127_1062425_0 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000003036 199.0
HKD1_k127_107090_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 560.0
HKD1_k127_107090_1 ABC transporter K02013 - 3.6.3.34 0.000000297 58.0
HKD1_k127_1072238_0 Alpha-amylase domain K01176 - 3.2.1.1 5.541e-213 672.0
HKD1_k127_1072238_1 Belongs to the ABC transporter superfamily K05816,K10111,K10112 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 516.0
HKD1_k127_1072238_2 Bacterial extracellular solute-binding protein K10108,K15770 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 466.0
HKD1_k127_1084139_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.291e-236 741.0
HKD1_k127_1084139_1 Na H antiporter K03315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 399.0
HKD1_k127_1084139_2 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 348.0
HKD1_k127_1084139_3 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000126 230.0
HKD1_k127_1084139_4 Histidine kinase K11383 - 2.7.13.3 0.00000000000000000000000000000000000000006365 169.0
HKD1_k127_1084139_5 cheY-homologous receiver domain K07658 - - 0.000000000000000000000000001792 126.0
HKD1_k127_1084139_6 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000003308 94.0
HKD1_k127_112485_0 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 456.0
HKD1_k127_112485_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000001077 109.0
HKD1_k127_113132_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 2.498e-247 779.0
HKD1_k127_113132_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 388.0
HKD1_k127_113132_2 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 323.0
HKD1_k127_113132_3 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006069 233.0
HKD1_k127_113132_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000000000000000001885 219.0
HKD1_k127_113132_5 ABC-type multidrug transport system ATPase component K01990,K09695 - - 0.00000000000000000000000000000000000000000000001876 190.0
HKD1_k127_113132_6 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000003322 124.0
HKD1_k127_113132_7 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000000000000004804 100.0
HKD1_k127_113132_8 Major Facilitator Superfamily - - - 0.000000000000000000006858 105.0
HKD1_k127_113132_9 GntR family transcriptional regulator K07979 - - 0.0009609 51.0
HKD1_k127_1132828_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 318.0
HKD1_k127_1156880_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 2.253e-198 629.0
HKD1_k127_1156880_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 304.0
HKD1_k127_1156880_10 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000001455 176.0
HKD1_k127_1156880_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000001063 165.0
HKD1_k127_1156880_12 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000004225 139.0
HKD1_k127_1156880_13 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000001308 136.0
HKD1_k127_1156880_14 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000001709 133.0
HKD1_k127_1156880_15 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000002558 129.0
HKD1_k127_1156880_16 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000002369 130.0
HKD1_k127_1156880_17 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000001207 100.0
HKD1_k127_1156880_18 Regulatory protein ArsR - - - 0.0000000000000000000006033 101.0
HKD1_k127_1156880_19 Ribosomal protein L36 K02919 - - 0.0000000000002467 70.0
HKD1_k127_1156880_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 304.0
HKD1_k127_1156880_20 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000005577 54.0
HKD1_k127_1156880_22 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000001319 59.0
HKD1_k127_1156880_23 TIGRFAM TonB family C-terminal domain K03832 - - 0.000004479 59.0
HKD1_k127_1156880_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 283.0
HKD1_k127_1156880_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000005523 246.0
HKD1_k127_1156880_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000001321 237.0
HKD1_k127_1156880_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001035 203.0
HKD1_k127_1156880_7 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000008305 189.0
HKD1_k127_1156880_8 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000002091 192.0
HKD1_k127_1156880_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000006152 195.0
HKD1_k127_1156960_0 Thermolysin metallopeptidase, alpha-helical domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 468.0
HKD1_k127_1156960_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 368.0
HKD1_k127_1156960_2 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 356.0
HKD1_k127_1156960_3 - - - - 0.00000000000000000000000001284 126.0
HKD1_k127_1156960_4 - - - - 0.00000000000000004045 84.0
HKD1_k127_1164431_0 Aminotransferase class I and II K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 428.0
HKD1_k127_1164431_1 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 295.0
HKD1_k127_1164431_2 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000006877 162.0
HKD1_k127_1164431_3 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000007011 136.0
HKD1_k127_1164431_4 - - - - 0.0000000000000000000005279 105.0
HKD1_k127_1164726_0 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 2.225e-219 695.0
HKD1_k127_1164726_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 402.0
HKD1_k127_1164726_2 PFAM Alpha beta hydrolase K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 362.0
HKD1_k127_1164726_3 aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000008025 225.0
HKD1_k127_1164726_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000001363 162.0
HKD1_k127_1164726_5 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000162 157.0
HKD1_k127_1164726_6 chaperone-mediated protein folding - - - 0.00000004425 67.0
HKD1_k127_1182787_0 COG1472 Beta-glucosidase-related glycosidases K05349 - 3.2.1.21 2.701e-260 818.0
HKD1_k127_1182787_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 1.867e-217 686.0
HKD1_k127_1182787_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 492.0
HKD1_k127_1182787_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 414.0
HKD1_k127_1182787_4 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 368.0
HKD1_k127_1182787_5 ADP binding - - - 0.0000000000000000000000000000000000000000000000000000001398 219.0
HKD1_k127_1182787_6 DinB family - - - 0.000000000000000000000000000000000000007826 152.0
HKD1_k127_1182787_7 Domain of unknown function (DUF1846) - - - 0.00000000000000000002531 93.0
HKD1_k127_1208918_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 526.0
HKD1_k127_1224079_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000002518 209.0
HKD1_k127_1224079_1 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000013 142.0
HKD1_k127_1224079_2 Aminotransferase, class I - - - 0.0001499 45.0
HKD1_k127_1270686_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1268.0
HKD1_k127_1270686_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.39e-307 956.0
HKD1_k127_1270686_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001251 229.0
HKD1_k127_1270686_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000002284 203.0
HKD1_k127_1270686_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000002684 73.0
HKD1_k127_129148_0 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000002985 203.0
HKD1_k127_129148_1 PFAM TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000007582 104.0
HKD1_k127_1293041_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 587.0
HKD1_k127_1293041_1 regulation of microtubule-based process K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 490.0
HKD1_k127_1293041_10 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000001774 197.0
HKD1_k127_1293041_11 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000002512 204.0
HKD1_k127_1293041_12 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000003312 121.0
HKD1_k127_1293041_13 Putative regulatory protein - - - 0.000000000000000000000001446 110.0
HKD1_k127_1293041_14 - - - - 0.0000000000000000003989 94.0
HKD1_k127_1293041_15 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.00000001525 66.0
HKD1_k127_1293041_16 protoporphyrinogen oxidase activity K00231 - 1.3.3.15,1.3.3.4 0.00000009054 53.0
HKD1_k127_1293041_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 489.0
HKD1_k127_1293041_3 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 479.0
HKD1_k127_1293041_4 Protein of unknown function, DUF255 K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 369.0
HKD1_k127_1293041_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 350.0
HKD1_k127_1293041_6 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 326.0
HKD1_k127_1293041_7 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003751 277.0
HKD1_k127_1293041_8 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000005739 235.0
HKD1_k127_1293041_9 DEAD DEAH box helicase domain protein K06877 - - 0.000000000000000000000000000000000000000000000000000008845 195.0
HKD1_k127_1304988_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 607.0
HKD1_k127_1304988_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 447.0
HKD1_k127_1304988_2 galactose-1-phosphate K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 399.0
HKD1_k127_1304988_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000001064 190.0
HKD1_k127_1304988_4 - - - - 0.000000000000000000417 91.0
HKD1_k127_1304988_5 oxidoreductase activity - - - 0.0000000000002477 83.0
HKD1_k127_1304988_6 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0000000000159 68.0
HKD1_k127_1304988_7 oxidoreductase activity - - - 0.0000001452 64.0
HKD1_k127_1333286_0 TIGRFAM cysteine desulfurase family protein, VC1184 subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 511.0
HKD1_k127_1333286_1 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 352.0
HKD1_k127_1333286_2 transport protein CorA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 325.0
HKD1_k127_1333286_3 - - - - 0.00000000000000000000000000003245 130.0
HKD1_k127_1333286_4 Dodecin K09165 - - 0.000000000000000002521 91.0
HKD1_k127_1359392_0 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 453.0
HKD1_k127_1359392_1 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 439.0
HKD1_k127_1359392_10 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000004588 152.0
HKD1_k127_1359392_11 Predicted membrane protein (DUF2177) - - - 0.000000000000000000000000000000002915 132.0
HKD1_k127_1359392_12 methyltransferase activity - - - 0.000000000000000000007025 100.0
HKD1_k127_1359392_13 Cupin 2, conserved barrel domain protein - - - 0.000000000000000001322 93.0
HKD1_k127_1359392_14 - - - - 0.00001705 54.0
HKD1_k127_1359392_2 Memo-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004891 278.0
HKD1_k127_1359392_3 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000005053 245.0
HKD1_k127_1359392_4 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000008756 248.0
HKD1_k127_1359392_5 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000007324 207.0
HKD1_k127_1359392_6 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000001162 217.0
HKD1_k127_1359392_7 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000006984 209.0
HKD1_k127_1359392_8 PFAM TspO MBR family K05770 - - 0.000000000000000000000000000000000000000005153 159.0
HKD1_k127_1359392_9 PA domain K14647 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000001175 159.0
HKD1_k127_137111_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.417e-247 775.0
HKD1_k127_137111_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 533.0
HKD1_k127_137111_10 Protein of unknown function (DUF3179) - - - 0.0000000000000000000000000000000000000000001695 175.0
HKD1_k127_137111_11 Cytochrome oxidase assembly protein K02259,K03110 - - 0.000000000000000000000000000000000000001584 166.0
HKD1_k127_137111_12 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000004726 117.0
HKD1_k127_137111_13 Alg9-like mannosyltransferase family K05286 - - 0.00000000000000001328 96.0
HKD1_k127_137111_14 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000009633 89.0
HKD1_k127_137111_15 MarR family - - - 0.00002835 52.0
HKD1_k127_137111_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 471.0
HKD1_k127_137111_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 469.0
HKD1_k127_137111_4 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 362.0
HKD1_k127_137111_5 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 316.0
HKD1_k127_137111_6 PFAM MscS Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004573 304.0
HKD1_k127_137111_7 Heme copper-type cytochrome quinol oxidase, subunit K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002185 276.0
HKD1_k127_137111_8 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000001141 223.0
HKD1_k127_137111_9 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000649 222.0
HKD1_k127_1384304_0 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000004707 144.0
HKD1_k127_1384304_1 beta-lactamase - - - 0.00000000000000000000000000001766 130.0
HKD1_k127_1384304_2 - - - - 0.000000000000000000000000005781 115.0
HKD1_k127_1384304_3 GYD domain - - - 0.000000000000000000000003871 108.0
HKD1_k127_1385006_0 PFAM Carbamoyl-phosphate synthase L chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 2.654e-227 729.0
HKD1_k127_1385006_1 Membrane dipeptidase (Peptidase family M19) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 460.0
HKD1_k127_1385006_2 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 400.0
HKD1_k127_1385006_3 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 337.0
HKD1_k127_1385006_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000672 278.0
HKD1_k127_1385006_5 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000644 239.0
HKD1_k127_1385006_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002566 240.0
HKD1_k127_1385006_7 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000002035 119.0
HKD1_k127_1385006_8 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000002718 120.0
HKD1_k127_1427995_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 600.0
HKD1_k127_1427995_1 Peptidase dimerisation domain K01451 - 3.5.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 493.0
HKD1_k127_1427995_10 Type IV secretion-system coupling protein DNA-binding domain K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005564 259.0
HKD1_k127_1427995_11 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000001105 224.0
HKD1_k127_1427995_12 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000799 190.0
HKD1_k127_1427995_13 DoxX K15977 - - 0.00000000000000000000000000000000000000000000001822 175.0
HKD1_k127_1427995_14 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000002544 181.0
HKD1_k127_1427995_15 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000709 156.0
HKD1_k127_1427995_16 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000001421 149.0
HKD1_k127_1427995_17 geranylgeranyl reductase activity - - - 0.000000000000000000000000000000000275 147.0
HKD1_k127_1427995_18 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000004331 139.0
HKD1_k127_1427995_19 Protein of unknown function DUF58 - - - 0.00000000000000000000000001507 122.0
HKD1_k127_1427995_2 CBS domain containing protein K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 505.0
HKD1_k127_1427995_20 PAP2 superfamily - - - 0.0000000000000000000000002513 117.0
HKD1_k127_1427995_21 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000001005 106.0
HKD1_k127_1427995_22 Pilus assembly protein, PilP - - - 0.00000000000000842 79.0
HKD1_k127_1427995_23 serine protease K07403 - - 0.0000000456 61.0
HKD1_k127_1427995_24 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.000000727 57.0
HKD1_k127_1427995_25 Bacterial SH3 domain K01876 - 6.1.1.12 0.00006317 55.0
HKD1_k127_1427995_26 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00038 53.0
HKD1_k127_1427995_3 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 384.0
HKD1_k127_1427995_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 330.0
HKD1_k127_1427995_5 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 339.0
HKD1_k127_1427995_6 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 327.0
HKD1_k127_1427995_7 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 301.0
HKD1_k127_1427995_8 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 297.0
HKD1_k127_1427995_9 PFAM ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003857 284.0
HKD1_k127_1478483_0 proline dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 452.0
HKD1_k127_1478483_1 aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 398.0
HKD1_k127_1478483_2 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000005073 72.0
HKD1_k127_1494510_0 N,N-dimethylaniline monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 521.0
HKD1_k127_1494510_1 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000001803 141.0
HKD1_k127_1494510_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000003284 78.0
HKD1_k127_1495843_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1049.0
HKD1_k127_1495843_1 Phosphotransferase enzyme family - - - 1.588e-280 897.0
HKD1_k127_1495843_10 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 388.0
HKD1_k127_1495843_11 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 385.0
HKD1_k127_1495843_12 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 352.0
HKD1_k127_1495843_13 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 339.0
HKD1_k127_1495843_14 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 328.0
HKD1_k127_1495843_15 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 322.0
HKD1_k127_1495843_16 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 301.0
HKD1_k127_1495843_17 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006537 287.0
HKD1_k127_1495843_19 Tricorn protease C1 domain K08676 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004887 260.0
HKD1_k127_1495843_2 Oligopeptide transporter OPT - - - 5.33e-247 782.0
HKD1_k127_1495843_20 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000711 260.0
HKD1_k127_1495843_21 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000007457 211.0
HKD1_k127_1495843_22 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000008206 214.0
HKD1_k127_1495843_23 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000003323 204.0
HKD1_k127_1495843_24 ABC transporter, ATP-binding protein K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000008658 201.0
HKD1_k127_1495843_26 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 - 3.5.4.1,3.5.4.33 0.0000000000000000000000000000000000000000000005779 171.0
HKD1_k127_1495843_27 transmembrane transport - - - 0.00000000000000000000000000000000000000001344 164.0
HKD1_k127_1495843_28 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000005128 139.0
HKD1_k127_1495843_29 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000002024 146.0
HKD1_k127_1495843_3 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 631.0
HKD1_k127_1495843_30 hydrolase (HAD superfamily) K07026 - 3.1.3.70 0.00000000000000000000000000000003018 137.0
HKD1_k127_1495843_31 histidine kinase A domain protein - - - 0.000000000000000000000000000001272 132.0
HKD1_k127_1495843_32 Ribonuclease H K03469 - 3.1.26.4 0.00000000000000000000000000004357 121.0
HKD1_k127_1495843_33 Tetratricopeptide repeat K08309 - - 0.0000000000000000000000008406 122.0
HKD1_k127_1495843_34 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000001726 86.0
HKD1_k127_1495843_35 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000002958 89.0
HKD1_k127_1495843_36 nuclear chromosome segregation - - - 0.0000000000002526 82.0
HKD1_k127_1495843_37 DivIVA domain K04074 - - 0.0000000003702 67.0
HKD1_k127_1495843_38 C4-type zinc ribbon domain K07164 - - 0.000000001543 68.0
HKD1_k127_1495843_4 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 572.0
HKD1_k127_1495843_40 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.00001745 55.0
HKD1_k127_1495843_5 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 514.0
HKD1_k127_1495843_6 UvrD-like helicase C-terminal domain K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 518.0
HKD1_k127_1495843_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 503.0
HKD1_k127_1495843_8 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 491.0
HKD1_k127_1495843_9 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 394.0
HKD1_k127_1552620_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1081.0
HKD1_k127_1552620_1 Succinyl-CoA ligase like flavodoxin domain K09181 - - 1.022e-265 841.0
HKD1_k127_1552620_10 GAF domain K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000004389 177.0
HKD1_k127_1552620_11 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000001016 150.0
HKD1_k127_1552620_12 short chain amide porin - - - 0.00000000000005177 84.0
HKD1_k127_1552620_2 Involved in the tonB-independent uptake of proteins - - - 2.424e-224 723.0
HKD1_k127_1552620_3 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 466.0
HKD1_k127_1552620_4 Protein kinase domain K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 455.0
HKD1_k127_1552620_5 C4-dicarboxylate anaerobic carrier - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 406.0
HKD1_k127_1552620_6 PFAM GPR1 FUN34 yaaH family K07034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001431 272.0
HKD1_k127_1552620_7 CBS domain K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003203 255.0
HKD1_k127_1552620_8 PFAM regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000008832 223.0
HKD1_k127_1552620_9 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000006972 221.0
HKD1_k127_1842622_0 O-Antigen ligase K18814 - - 0.00000000000000000000000000001526 132.0
HKD1_k127_1842622_1 PFAM Glycosyl transferase, group 1 K08256 - 2.4.1.345 0.000000000000003003 87.0
HKD1_k127_1842622_2 Thiolase, C-terminal domain - - - 0.0000000002227 61.0
HKD1_k127_1842622_3 Belongs to the UPF0434 family K09791 - - 0.000000000428 68.0
HKD1_k127_1863964_0 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 536.0
HKD1_k127_186706_0 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 301.0
HKD1_k127_186706_1 electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000673 162.0
HKD1_k127_187969_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000001644 154.0
HKD1_k127_187969_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000002421 96.0
HKD1_k127_187969_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000008633 65.0
HKD1_k127_190479_0 TIGRFAM 2-oxoglutarate dehydrogenase, E1 K00164,K01616 - 1.2.4.2,4.1.1.71 0.0 1284.0
HKD1_k127_190479_1 glycosyltransferase 36 associated - - - 2.311e-219 706.0
HKD1_k127_190479_2 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 1.109e-210 664.0
HKD1_k127_190479_3 coagulation factor 5 8 type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 473.0
HKD1_k127_190479_4 phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000000000000000000000004013 214.0
HKD1_k127_190479_5 Pfam Family of - - - 0.00000006263 54.0
HKD1_k127_2025991_0 tagaturonate epimerase - - - 1.68e-208 666.0
HKD1_k127_2025991_1 PfkB domain protein K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 608.0
HKD1_k127_2025991_10 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000603 195.0
HKD1_k127_2025991_2 Glucuronate isomerase K01812 - 5.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 611.0
HKD1_k127_2025991_3 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 612.0
HKD1_k127_2025991_4 PFAM Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 584.0
HKD1_k127_2025991_5 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 491.0
HKD1_k127_2025991_6 lactate racemase activity K22373 - 5.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 496.0
HKD1_k127_2025991_7 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 348.0
HKD1_k127_2025991_8 PFAM secretion protein HlyD family protein K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 317.0
HKD1_k127_2025991_9 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000009965 237.0
HKD1_k127_2029167_0 3-isopropylmalate dehydratase activity K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 1.044e-303 943.0
HKD1_k127_2029167_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.111e-228 737.0
HKD1_k127_2029167_10 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000271 223.0
HKD1_k127_2029167_11 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000007982 210.0
HKD1_k127_2029167_12 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000002679 171.0
HKD1_k127_2029167_13 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000002694 165.0
HKD1_k127_2029167_14 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000004765 140.0
HKD1_k127_2029167_15 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000002877 119.0
HKD1_k127_2029167_16 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000006225 93.0
HKD1_k127_2029167_17 Fibronectin type 3 domain - - - 0.000000000000001762 89.0
HKD1_k127_2029167_18 TIGRFAM TonB family protein K03832 - - 0.000000000001454 78.0
HKD1_k127_2029167_2 MmgE/PrpD family K01720 - 4.2.1.79 2.985e-211 680.0
HKD1_k127_2029167_3 C-terminal, D2-small domain, of ClpB protein K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 500.0
HKD1_k127_2029167_4 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 466.0
HKD1_k127_2029167_5 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 394.0
HKD1_k127_2029167_6 Sodium:dicarboxylate symporter family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009592 358.0
HKD1_k127_2029167_7 mRNA catabolic process K06950,K09163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000851 277.0
HKD1_k127_2029167_8 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003043 265.0
HKD1_k127_2029167_9 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000006523 235.0
HKD1_k127_2033382_0 Two component regulator propeller K07315,K12132,K13924 - 2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3 2.898e-253 818.0
HKD1_k127_2033382_1 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 605.0
HKD1_k127_2033382_10 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000001298 186.0
HKD1_k127_2033382_11 Poly(ADP-ribose) polymerase catalytic domain K10799 GO:0000209,GO:0000228,GO:0000242,GO:0000723,GO:0000781,GO:0000784,GO:0003674,GO:0003824,GO:0003950,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006139,GO:0006259,GO:0006464,GO:0006471,GO:0006725,GO:0006807,GO:0006996,GO:0008104,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010638,GO:0010639,GO:0010646,GO:0010647,GO:0012505,GO:0015630,GO:0016043,GO:0016567,GO:0016740,GO:0016757,GO:0016763,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0023051,GO:0023056,GO:0030111,GO:0030162,GO:0030177,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032200,GO:0032204,GO:0032205,GO:0032206,GO:0032210,GO:0032212,GO:0032268,GO:0032270,GO:0032446,GO:0032501,GO:0032502,GO:0033036,GO:0033043,GO:0033044,GO:0033365,GO:0034502,GO:0034613,GO:0034641,GO:0035264,GO:0036211,GO:0040007,GO:0040008,GO:0040014,GO:0042176,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043412,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044454,GO:0044464,GO:0045732,GO:0045862,GO:0045934,GO:0045935,GO:0046483,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048638,GO:0050789,GO:0050793,GO:0050794,GO:0051052,GO:0051053,GO:0051054,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051239,GO:0051246,GO:0051247,GO:0051276,GO:0051641,GO:0060249,GO:0060255,GO:0060828,GO:0065007,GO:0065008,GO:0070013,GO:0070198,GO:0070212,GO:0070213,GO:0070647,GO:0070727,GO:0071704,GO:0071840,GO:0080090,GO:0090263,GO:0090304,GO:0090364,GO:0097110,GO:0098687,GO:1901360,GO:1901564,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1904353,GO:1904355,GO:1904356,GO:1904357,GO:1904358,GO:2000058,GO:2000060,GO:2000112,GO:2000278,GO:2000573,GO:2001251,GO:2001252 2.4.2.30 0.00000000000000000149 100.0
HKD1_k127_2033382_12 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000748 93.0
HKD1_k127_2033382_13 Protein conserved in bacteria - - - 0.00000000000000002307 91.0
HKD1_k127_2033382_14 Carboxypeptidase - - - 0.00000000007293 70.0
HKD1_k127_2033382_15 - K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0001078 52.0
HKD1_k127_2033382_2 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 417.0
HKD1_k127_2033382_3 DAHP synthetase I family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 375.0
HKD1_k127_2033382_4 Zn_pept - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 374.0
HKD1_k127_2033382_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 333.0
HKD1_k127_2033382_6 hydrolase of the alpha beta superfamily K07017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007636 273.0
HKD1_k127_2033382_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000001582 223.0
HKD1_k127_2033382_8 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001156 232.0
HKD1_k127_2033382_9 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000543 207.0
HKD1_k127_203381_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 499.0
HKD1_k127_203381_1 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 428.0
HKD1_k127_203381_2 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 380.0
HKD1_k127_203381_3 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 367.0
HKD1_k127_203381_4 - - - - 0.00000000000000000000000000000000000000000000000000002462 200.0
HKD1_k127_203381_5 oxidoreductase activity - - - 0.0000000000000000006521 101.0
HKD1_k127_203381_6 bacterial OsmY and nodulation domain - - - 0.000000000000004506 84.0
HKD1_k127_203381_7 oxidoreductase activity - - - 0.000000000000004892 90.0
HKD1_k127_203381_8 Bacterial regulatory proteins, tetR family - - - 0.0000002203 60.0
HKD1_k127_203381_9 Psort location Cytoplasmic, score - - - 0.0001197 55.0
HKD1_k127_2034378_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.19e-277 876.0
HKD1_k127_2034378_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 7.306e-204 651.0
HKD1_k127_2034378_10 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.00000000001886 75.0
HKD1_k127_2034378_2 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 472.0
HKD1_k127_2034378_3 PFAM permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 456.0
HKD1_k127_2034378_4 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 305.0
HKD1_k127_2034378_5 Alpha beta - - - 0.00000000000000000000000000000000000000000000000000000006487 206.0
HKD1_k127_2034378_6 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000002464 165.0
HKD1_k127_2034378_7 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000388 153.0
HKD1_k127_2034378_8 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000278 128.0
HKD1_k127_2034378_9 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000002544 96.0
HKD1_k127_2039134_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 530.0
HKD1_k127_2039134_1 PFAM Uncharacterised conserved protein UCP033563 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 526.0
HKD1_k127_2039134_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 359.0
HKD1_k127_2039134_3 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 310.0
HKD1_k127_2039134_4 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000257 253.0
HKD1_k127_2039134_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000001717 222.0
HKD1_k127_2039134_6 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000004629 173.0
HKD1_k127_2039134_7 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000009962 142.0
HKD1_k127_2039134_8 Surface antigen K07277 - - 0.000000000000000000002942 109.0
HKD1_k127_2039134_9 Rdx family K07401 - - 0.000000000002485 68.0
HKD1_k127_2041893_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 543.0
HKD1_k127_2041893_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000002801 225.0
HKD1_k127_2041893_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000003089 141.0
HKD1_k127_2041893_3 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000003018 102.0
HKD1_k127_2041893_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000003536 105.0
HKD1_k127_2041893_5 mRNA binding - - - 0.00000000000001676 76.0
HKD1_k127_2041893_6 ig-like, plexins, transcription factors - - - 0.000000001148 70.0
HKD1_k127_2041893_7 Tetratricopeptide repeat - - - 0.000000002572 69.0
HKD1_k127_2041893_8 Roadblock/LC7 domain - - - 0.00000002186 62.0
HKD1_k127_2044307_0 pyrophosphate-energized membrane proton pump K01507 - 3.6.1.1 2.891e-286 897.0
HKD1_k127_2044307_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.117e-285 900.0
HKD1_k127_2044307_10 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 508.0
HKD1_k127_2044307_11 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 486.0
HKD1_k127_2044307_12 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 435.0
HKD1_k127_2044307_13 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 424.0
HKD1_k127_2044307_14 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 397.0
HKD1_k127_2044307_15 Psort location Cytoplasmic, score K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 353.0
HKD1_k127_2044307_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 338.0
HKD1_k127_2044307_17 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 334.0
HKD1_k127_2044307_18 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 332.0
HKD1_k127_2044307_19 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 319.0
HKD1_k127_2044307_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.339e-265 848.0
HKD1_k127_2044307_20 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 311.0
HKD1_k127_2044307_21 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009264 293.0
HKD1_k127_2044307_22 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000003636 248.0
HKD1_k127_2044307_23 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000005936 234.0
HKD1_k127_2044307_24 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000003799 219.0
HKD1_k127_2044307_25 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000001 230.0
HKD1_k127_2044307_26 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000005508 207.0
HKD1_k127_2044307_27 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000001169 201.0
HKD1_k127_2044307_28 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000001345 194.0
HKD1_k127_2044307_29 Bacterial DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000001221 180.0
HKD1_k127_2044307_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 8.699e-251 788.0
HKD1_k127_2044307_30 Appr-1-p processing domain protein - - - 0.000000000000000000000000000000000000000000009323 174.0
HKD1_k127_2044307_31 impB/mucB/samB family K14161 - - 0.00000000000000000000000000000000000000000007013 179.0
HKD1_k127_2044307_32 - - - - 0.0000000000000000000000000000000000000009887 158.0
HKD1_k127_2044307_33 - - - - 0.000000000000000000000000000000000000001622 157.0
HKD1_k127_2044307_34 PFAM Lytic K08309 - - 0.000000000000000000000000000000000000004097 156.0
HKD1_k127_2044307_35 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000001519 122.0
HKD1_k127_2044307_36 protein conserved in bacteria - - - 0.0000000000000000000000000001537 119.0
HKD1_k127_2044307_37 Transport and Golgi organisation 2 - - - 0.000000000000000000000000002273 121.0
HKD1_k127_2044307_38 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000002607 128.0
HKD1_k127_2044307_39 spore coat K01790 - 5.1.3.13 0.00000000000000000000000002657 115.0
HKD1_k127_2044307_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.661e-229 721.0
HKD1_k127_2044307_40 recA bacterial DNA recombination protein - - - 0.0000000000000000000002105 109.0
HKD1_k127_2044307_41 NifU-like domain - - - 0.0000000000000000003807 94.0
HKD1_k127_2044307_42 Lipopolysaccharide-assembly - - - 0.00000000000002333 81.0
HKD1_k127_2044307_43 DNA-templated transcription, initiation K03088 - - 0.00000000000003426 80.0
HKD1_k127_2044307_44 - - - - 0.00000003348 62.0
HKD1_k127_2044307_45 Protein of unknown function (DUF2905) - - - 0.00000003593 61.0
HKD1_k127_2044307_46 Modulates RecA activity K03565 - - 0.00000006013 61.0
HKD1_k127_2044307_47 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000001748 61.0
HKD1_k127_2044307_48 Helix-turn-helix XRE-family like proteins - - - 0.0000002301 62.0
HKD1_k127_2044307_49 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.0000008277 61.0
HKD1_k127_2044307_5 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 6.431e-217 681.0
HKD1_k127_2044307_50 Domain of unknown function (DUF4412) - - - 0.000002305 59.0
HKD1_k127_2044307_51 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000005794 59.0
HKD1_k127_2044307_52 Transglutaminase/protease-like homologues K22452 - 2.3.2.13 0.000006854 57.0
HKD1_k127_2044307_53 N-acetyltransferase activity K19001 GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747 - 0.00001637 55.0
HKD1_k127_2044307_54 Peptidase S24-like - - - 0.00002286 55.0
HKD1_k127_2044307_6 carboxypeptidase - - - 1.046e-209 684.0
HKD1_k127_2044307_7 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 569.0
HKD1_k127_2044307_8 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 520.0
HKD1_k127_2044307_9 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 517.0
HKD1_k127_2046103_0 peptidase S9 prolyl oligopeptidase active site - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 3.436e-269 846.0
HKD1_k127_2046103_1 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 336.0
HKD1_k127_2046103_2 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009234 256.0
HKD1_k127_2046103_3 dehydrogenases and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000001431 219.0
HKD1_k127_2046103_4 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000000000003201 147.0
HKD1_k127_2046103_5 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000009153 118.0
HKD1_k127_2046103_6 - - - - 0.00000000000000000001735 101.0
HKD1_k127_2046626_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 531.0
HKD1_k127_2046626_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 335.0
HKD1_k127_2046626_2 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000004176 153.0
HKD1_k127_205329_0 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 521.0
HKD1_k127_205329_1 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 342.0
HKD1_k127_205329_10 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000001638 142.0
HKD1_k127_205329_11 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000000155 134.0
HKD1_k127_205329_12 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.000000000000000000000001317 113.0
HKD1_k127_205329_13 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000002303 119.0
HKD1_k127_205329_14 Alpha beta - - - 0.000000000000000000001012 106.0
HKD1_k127_205329_15 DinB family - - - 0.0000000001614 70.0
HKD1_k127_205329_2 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006228 270.0
HKD1_k127_205329_3 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005159 263.0
HKD1_k127_205329_4 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000001751 270.0
HKD1_k127_205329_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K15876 - - 0.00000000000000000000000000000000000000000001115 169.0
HKD1_k127_205329_6 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000006762 158.0
HKD1_k127_205329_7 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000111 156.0
HKD1_k127_205329_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000002141 156.0
HKD1_k127_205329_9 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000006962 150.0
HKD1_k127_2063428_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 567.0
HKD1_k127_2063428_1 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 496.0
HKD1_k127_2063428_10 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000001727 186.0
HKD1_k127_2063428_11 Beta-lactamase - - - 0.0000000000000000000000000000000000000000001612 182.0
HKD1_k127_2063428_12 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000264 175.0
HKD1_k127_2063428_13 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000004272 168.0
HKD1_k127_2063428_14 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000006086 167.0
HKD1_k127_2063428_15 Methyltransferase domain - - - 0.00000000000000000000000000000000000000007883 166.0
HKD1_k127_2063428_16 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000007589 162.0
HKD1_k127_2063428_17 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000004897 139.0
HKD1_k127_2063428_18 OsmC-like protein K07397 - - 0.000000000000000000000000001513 117.0
HKD1_k127_2063428_19 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000003375 122.0
HKD1_k127_2063428_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 426.0
HKD1_k127_2063428_20 transporter K07238,K11021 - - 0.00000000000000000000005939 108.0
HKD1_k127_2063428_21 Peptidase family M23 K21471 - - 0.00000000000000000000365 109.0
HKD1_k127_2063428_22 PFAM FecR protein - - - 0.0000000000000000006436 100.0
HKD1_k127_2063428_23 ATPases associated with a variety of cellular activities - - - 0.0000000000000000188 84.0
HKD1_k127_2063428_24 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000002322 94.0
HKD1_k127_2063428_25 Involved in formation and maintenance of cell shape K03570 - - 0.00000000001632 76.0
HKD1_k127_2063428_26 Neuraminyllactose-binding hemagglutinin precursor (NLBH) K15846 - - 0.0000000005242 70.0
HKD1_k127_2063428_27 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit K04762 - - 0.000000002103 69.0
HKD1_k127_2063428_28 helix_turn_helix, Lux Regulon - - - 0.0000006633 59.0
HKD1_k127_2063428_3 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009157 422.0
HKD1_k127_2063428_4 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 422.0
HKD1_k127_2063428_5 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 366.0
HKD1_k127_2063428_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 310.0
HKD1_k127_2063428_7 synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 293.0
HKD1_k127_2063428_8 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000006374 267.0
HKD1_k127_2063428_9 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000001174 229.0
HKD1_k127_2076555_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 613.0
HKD1_k127_2076555_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 421.0
HKD1_k127_2076555_2 membrane - - - 0.000000000000000000000000000000000000000000000000000007617 198.0
HKD1_k127_2076555_3 - - - - 0.0000000000000000000008901 98.0
HKD1_k127_2087437_0 PFAM Aldehyde dehydrogenase K00128,K00131,K00135,K00140 - 1.2.1.16,1.2.1.18,1.2.1.20,1.2.1.27,1.2.1.3,1.2.1.79,1.2.1.9 1.488e-237 745.0
HKD1_k127_2087437_1 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 310.0
HKD1_k127_2087437_2 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 314.0
HKD1_k127_2087437_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 273.0
HKD1_k127_2087437_4 Glucokinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000009206 278.0
HKD1_k127_2087437_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000002059 172.0
HKD1_k127_2094166_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 322.0
HKD1_k127_2094166_1 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 331.0
HKD1_k127_2094166_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000004443 184.0
HKD1_k127_2094166_3 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.0000000000000000000006507 101.0
HKD1_k127_2094166_4 STAS domain K04749 - - 0.0000000000000001362 84.0
HKD1_k127_2094166_5 adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility K18968 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.00000006797 63.0
HKD1_k127_2100157_0 PFAM Chromate transporter K07240 - - 0.0000000000000000000000000000262 131.0
HKD1_k127_2100157_1 Belongs to the GcvT family K06980 - - 0.00000000000000000000002116 112.0
HKD1_k127_2100157_2 of the beta-lactamase K00784 - 3.1.26.11 0.00000000304 61.0
HKD1_k127_2114409_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.321e-253 799.0
HKD1_k127_2114409_1 PFAM glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 365.0
HKD1_k127_2114409_10 Radical SAM superfamily - - - 0.0000000000000000000000000000000001295 151.0
HKD1_k127_2114409_11 CoA binding domain K06929 - - 0.0000000000000000000000000001121 120.0
HKD1_k127_2114409_12 - - - - 0.000000000000000000000000001484 115.0
HKD1_k127_2114409_13 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000005187 107.0
HKD1_k127_2114409_14 Glycosyl transferase, family 2 - - - 0.000000000000000005588 96.0
HKD1_k127_2114409_15 Glycosyl transferase K20444 - - 0.0000000000000001659 93.0
HKD1_k127_2114409_16 unfolded protein binding K06142 - - 0.000000002797 70.0
HKD1_k127_2114409_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 314.0
HKD1_k127_2114409_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 302.0
HKD1_k127_2114409_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000001723 258.0
HKD1_k127_2114409_5 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001031 251.0
HKD1_k127_2114409_6 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000002309 209.0
HKD1_k127_2114409_7 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000008776 194.0
HKD1_k127_2114409_8 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000001663 183.0
HKD1_k127_2114409_9 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000661 146.0
HKD1_k127_2122291_0 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 2.304e-295 929.0
HKD1_k127_2122291_1 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000007446 196.0
HKD1_k127_213092_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 309.0
HKD1_k127_213092_1 protein conserved in bacteria (DUF2329) - - - 0.00000000002105 74.0
HKD1_k127_2173702_0 serine-type endopeptidase activity K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002223 254.0
HKD1_k127_2173702_2 RNA polymerase sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000007126 226.0
HKD1_k127_2173702_3 gluconolactonase activity - - - 0.00000000000000000000000000000001699 139.0
HKD1_k127_2173702_4 - - - - 0.00000000000000000000304 104.0
HKD1_k127_217664_0 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003707 291.0
HKD1_k127_217664_1 Domain of unknown function (DUF1956) - - - 0.0000000000000000000000005656 113.0
HKD1_k127_217664_2 Biotin-lipoyl like K07799 - - 0.0000000000000000000005373 106.0
HKD1_k127_2188720_0 AMP-binding enzyme - - - 2.403e-224 714.0
HKD1_k127_2188720_1 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 486.0
HKD1_k127_2188720_2 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 424.0
HKD1_k127_2188720_3 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 378.0
HKD1_k127_2188720_4 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008199 272.0
HKD1_k127_2188720_5 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.000000000000000000000000000000000000000000000000000000000005039 216.0
HKD1_k127_2188720_6 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000009766 178.0
HKD1_k127_2188720_8 Tetratricopeptide repeat - - - 0.0000000000000000003859 97.0
HKD1_k127_2188720_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000008322 71.0
HKD1_k127_2197769_0 Peptidase M14, carboxypeptidase A - - - 2.718e-266 852.0
HKD1_k127_2197769_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 389.0
HKD1_k127_2197769_10 PAP2 superfamily - - - 0.0000000000000000000000000001452 132.0
HKD1_k127_2197769_11 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000006757 102.0
HKD1_k127_2197769_12 - - - - 0.0000000000003049 72.0
HKD1_k127_2197769_13 Putative regulatory protein - - - 0.0000001856 60.0
HKD1_k127_2197769_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 360.0
HKD1_k127_2197769_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001079 243.0
HKD1_k127_2197769_4 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003978 232.0
HKD1_k127_2197769_5 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000006914 185.0
HKD1_k127_2197769_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000001457 161.0
HKD1_k127_2197769_7 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000001736 145.0
HKD1_k127_2197769_8 - - - - 0.0000000000000000000000000000000003343 135.0
HKD1_k127_2197769_9 Transposase IS200 like - - - 0.00000000000000000000000000002037 130.0
HKD1_k127_2201234_0 Peptidase m28 - - - 2.027e-197 629.0
HKD1_k127_2201234_1 Diguanylate cyclase - - - 0.0000000000000105 81.0
HKD1_k127_2204681_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1019.0
HKD1_k127_2204681_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 430.0
HKD1_k127_2204681_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.0000000000000000000000000000000000428 143.0
HKD1_k127_2234351_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 294.0
HKD1_k127_2234351_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001942 284.0
HKD1_k127_2234351_2 MacB-like periplasmic core domain K02004 - - 0.00000002713 57.0
HKD1_k127_2268990_0 secondary active sulfate transmembrane transporter activity K06901 - - 4.519e-219 694.0
HKD1_k127_2268990_1 DEAD DEAH box helicase K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000004212 224.0
HKD1_k127_2268990_2 B3/4 domain - - - 0.00000000000000000007624 96.0
HKD1_k127_2269248_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 2.555e-197 625.0
HKD1_k127_2269248_1 kinase activity K02850 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.000000000000000000000000000000000000000000000000000192 206.0
HKD1_k127_2269248_2 B12 binding domain K14084 - - 0.0000000000000000000000000000000000000000000000001283 184.0
HKD1_k127_2269248_3 - - - - 0.000000000000000000000000000000000000000000006972 178.0
HKD1_k127_2269248_4 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000002347 149.0
HKD1_k127_2305584_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 487.0
HKD1_k127_2305584_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 366.0
HKD1_k127_2305584_2 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 350.0
HKD1_k127_2318599_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 344.0
HKD1_k127_2318599_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000349 294.0
HKD1_k127_2318599_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000971 207.0
HKD1_k127_2318599_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000001414 169.0
HKD1_k127_2318599_4 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000002764 111.0
HKD1_k127_2320677_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.548e-281 893.0
HKD1_k127_2320677_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 308.0
HKD1_k127_2320677_10 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000002887 159.0
HKD1_k127_2320677_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000005763 119.0
HKD1_k127_2320677_12 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000001011 112.0
HKD1_k127_2320677_13 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000007326 72.0
HKD1_k127_2320677_14 Protein of unknown function (DUF2914) - - - 0.000000000002406 78.0
HKD1_k127_2320677_15 outer membrane autotransporter barrel domain protein - - - 0.000000000004079 75.0
HKD1_k127_2320677_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002571 281.0
HKD1_k127_2320677_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000004267 270.0
HKD1_k127_2320677_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000001091 263.0
HKD1_k127_2320677_5 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000005367 235.0
HKD1_k127_2320677_6 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000002987 181.0
HKD1_k127_2320677_7 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000001526 191.0
HKD1_k127_2320677_8 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000002786 191.0
HKD1_k127_2320677_9 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000000000007565 157.0
HKD1_k127_232432_0 mannose metabolic process K01191 - 3.2.1.24 6.977e-292 941.0
HKD1_k127_232432_1 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 469.0
HKD1_k127_232432_2 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 433.0
HKD1_k127_232432_3 Outer membrane protein beta-barrel domain - - - 0.000000003866 66.0
HKD1_k127_232432_4 COG1404 Subtilisin-like serine proteases K20486 - - 0.0000003789 51.0
HKD1_k127_232432_5 ABC-type sugar transport system periplasmic component K10439 - - 0.00002177 48.0
HKD1_k127_2335581_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000002481 252.0
HKD1_k127_2335581_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000001082 154.0
HKD1_k127_2335581_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000005858 158.0
HKD1_k127_2382711_0 Zinc-binding dehydrogenase K22231 - - 4.244e-200 630.0
HKD1_k127_2382711_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 507.0
HKD1_k127_2382711_2 PFAM ABC transporter related K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 482.0
HKD1_k127_2382711_3 Belongs to the binding-protein-dependent transport system permease family K10439,K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 423.0
HKD1_k127_2382711_4 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 334.0
HKD1_k127_2382711_5 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 289.0
HKD1_k127_2382711_6 3-phytase (Myo-inositol-hexaphosphate 3-phosphohydrolase) K01083 - 3.1.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000003151 267.0
HKD1_k127_2382711_7 PFAM Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000002736 196.0
HKD1_k127_2390744_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001757 281.0
HKD1_k127_2390744_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001023 275.0
HKD1_k127_2390744_2 - - - - 0.000000000005833 78.0
HKD1_k127_2390744_3 Phage integrase family - - - 0.0004509 46.0
HKD1_k127_2390744_4 - - - - 0.0007293 49.0
HKD1_k127_2420695_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 8.223e-238 751.0
HKD1_k127_2420695_1 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 616.0
HKD1_k127_2420695_10 Bacterial Ig-like domain - - - 0.0000000000000166 88.0
HKD1_k127_2420695_11 alpha-galactosidase K07407 - 3.2.1.22 0.0000000000001424 84.0
HKD1_k127_2420695_12 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000001195 59.0
HKD1_k127_2420695_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 497.0
HKD1_k127_2420695_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 308.0
HKD1_k127_2420695_4 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000001025 259.0
HKD1_k127_2420695_5 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000726 252.0
HKD1_k127_2420695_6 - - - - 0.00000000000000000000000000000000000000000000000000000000009475 227.0
HKD1_k127_2420695_7 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000002414 196.0
HKD1_k127_2420695_8 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000007608 193.0
HKD1_k127_2420695_9 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000166 88.0
HKD1_k127_2424668_0 Involved in the tonB-independent uptake of proteins - - - 5.153e-198 646.0
HKD1_k127_2424668_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000001836 137.0
HKD1_k127_2424668_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00001681 48.0
HKD1_k127_2441620_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 402.0
HKD1_k127_2441620_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 351.0
HKD1_k127_2441620_10 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000001637 210.0
HKD1_k127_2441620_11 phosphatase activity K07025 - - 0.00000000000000000000000000000000000000000001325 171.0
HKD1_k127_2441620_12 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000001364 163.0
HKD1_k127_2441620_13 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000004996 162.0
HKD1_k127_2441620_14 Histidine kinase K02668,K07708 - 2.7.13.3 0.00000000000000000000000000000000003165 154.0
HKD1_k127_2441620_15 transferase activity, transferring glycosyl groups K12994 - 2.4.1.349 0.00000000000000000000000000000000148 145.0
HKD1_k127_2441620_16 Receptor family ligand binding region - - - 0.000000000000000000000000000001197 135.0
HKD1_k127_2441620_17 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000007601 109.0
HKD1_k127_2441620_18 - - - - 0.00000000000000000000000193 117.0
HKD1_k127_2441620_19 Glycosyl transferase, family 2 K20444 - - 0.00000000000000000000001309 115.0
HKD1_k127_2441620_2 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 342.0
HKD1_k127_2441620_20 Glycosyl transferase K20444 - - 0.00000000000000000004038 106.0
HKD1_k127_2441620_21 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - 0.00000000000001445 86.0
HKD1_k127_2441620_22 Protein of unknown function (DUF3891) - - - 0.00000000001467 74.0
HKD1_k127_2441620_23 Bacterial membrane protein, YfhO - - - 0.0000000000273 77.0
HKD1_k127_2441620_24 Bacterial membrane protein YfhO - - - 0.0000000005036 73.0
HKD1_k127_2441620_25 general secretion pathway protein K02456 - - 0.000000001916 66.0
HKD1_k127_2441620_26 -O-antigen K02847,K13009 - - 0.00000005886 66.0
HKD1_k127_2441620_27 Glycosyl transferase family 41 - - - 0.0000007715 62.0
HKD1_k127_2441620_28 Bacterial membrane protein YfhO - - - 0.000004683 60.0
HKD1_k127_2441620_3 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 316.0
HKD1_k127_2441620_30 Alpha beta - - - 0.00002147 56.0
HKD1_k127_2441620_31 -O-antigen K07234 - - 0.0003346 53.0
HKD1_k127_2441620_4 Mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 306.0
HKD1_k127_2441620_5 Flavin containing amine oxidoreductase K00231,K01854 - 1.3.3.15,1.3.3.4,5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 312.0
HKD1_k127_2441620_6 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 295.0
HKD1_k127_2441620_7 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000441 282.0
HKD1_k127_2441620_8 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 275.0
HKD1_k127_2441620_9 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000002877 252.0
HKD1_k127_244601_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 385.0
HKD1_k127_244601_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 293.0
HKD1_k127_244601_10 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000001779 107.0
HKD1_k127_244601_11 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000003026 93.0
HKD1_k127_244601_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000009021 76.0
HKD1_k127_244601_13 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000118 73.0
HKD1_k127_244601_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000001396 236.0
HKD1_k127_244601_3 Ribosomal protein L16p/L10e K02878 - - 0.000000000000000000000000000000000000000000000000000000000000002184 223.0
HKD1_k127_244601_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000008579 178.0
HKD1_k127_244601_5 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000123 181.0
HKD1_k127_244601_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000006196 174.0
HKD1_k127_244601_7 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000003839 148.0
HKD1_k127_244601_8 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000003542 125.0
HKD1_k127_244601_9 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000008245 115.0
HKD1_k127_2486332_0 Acyclic terpene utilisation family protein AtuA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 556.0
HKD1_k127_2486332_1 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 430.0
HKD1_k127_2486332_2 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000003918 222.0
HKD1_k127_2490800_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 496.0
HKD1_k127_2490800_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 484.0
HKD1_k127_2490800_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000002001 179.0
HKD1_k127_2490800_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K10819 - 2.7.13.3 0.0000000000000000000000000000000003432 154.0
HKD1_k127_2490800_12 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000001606 121.0
HKD1_k127_2490800_13 ATPase or kinase K06925 - - 0.0000000000000000000005784 103.0
HKD1_k127_2490800_15 - - - - 0.000000000008834 76.0
HKD1_k127_2490800_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 396.0
HKD1_k127_2490800_3 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 353.0
HKD1_k127_2490800_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000108 267.0
HKD1_k127_2490800_5 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000002644 250.0
HKD1_k127_2490800_6 Short-chain dehydrogenase reductase SDR K00059,K00076,K00216,K03366,K13774,K18337 - 1.1.1.100,1.1.1.159,1.1.1.173,1.1.1.304,1.1.1.377,1.1.1.378,1.1.1.76,1.3.1.28 0.00000000000000000000000000000000000000000000000000000000000512 226.0
HKD1_k127_2490800_7 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000002005 195.0
HKD1_k127_2490800_8 O-methyltransferase, family 2 - - - 0.000000000000000000000000000000000000000000000005786 184.0
HKD1_k127_2490800_9 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000001115 172.0
HKD1_k127_2521646_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 347.0
HKD1_k127_2521646_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000009614 265.0
HKD1_k127_2531964_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009512 596.0
HKD1_k127_2531964_1 lipid A export permease ATP-binding protein MsbA K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 442.0
HKD1_k127_2531964_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002882 278.0
HKD1_k127_2531964_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000003294 201.0
HKD1_k127_2531964_4 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000007269 180.0
HKD1_k127_2531964_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000002068 104.0
HKD1_k127_2531964_6 - - - - 0.00000000000000000000005047 103.0
HKD1_k127_2531964_7 long-chain fatty acid transport protein - - - 0.0000000000000000001677 93.0
HKD1_k127_2555599_0 Cation transporter/ATPase, N-terminus K01531,K16905 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2 0.0 1348.0
HKD1_k127_2555599_1 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 371.0
HKD1_k127_2555599_2 Nadph-dependent fmn reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 340.0
HKD1_k127_2555599_3 Amidohydrolase family - - - 0.0000005753 52.0
HKD1_k127_2555807_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 2.341e-264 827.0
HKD1_k127_2555807_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.16e-209 690.0
HKD1_k127_2555807_2 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 4.384e-206 649.0
HKD1_k127_2558870_0 Glycine radical K00656,K07540,K20038 - 2.3.1.54,4.1.99.11,4.3.99.4 0.0 1239.0
HKD1_k127_2558870_1 PFAM peptidase K01284,K01414 - 3.4.15.5,3.4.24.70 2.129e-272 856.0
HKD1_k127_2558870_10 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000008315 132.0
HKD1_k127_2558870_11 Protein tyrosine kinase - - - 0.00000000000000000000000000002709 134.0
HKD1_k127_2558870_12 Serine aminopeptidase, S33 - - - 0.00000000000000000000000001316 121.0
HKD1_k127_2558870_13 peptidase U32 - - - 0.00000000000000000001644 95.0
HKD1_k127_2558870_14 - - - - 0.00000000000000001045 96.0
HKD1_k127_2558870_15 Intracellular proteinase inhibitor - - - 0.00000000000006438 84.0
HKD1_k127_2558870_16 PQQ-like domain - - - 0.000000000000093 82.0
HKD1_k127_2558870_17 PQQ enzyme repeat - - - 0.00000000000115 73.0
HKD1_k127_2558870_18 - - - - 0.000000003321 59.0
HKD1_k127_2558870_2 Zinc-binding dehydrogenase K12957 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 332.0
HKD1_k127_2558870_3 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 316.0
HKD1_k127_2558870_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 304.0
HKD1_k127_2558870_5 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 300.0
HKD1_k127_2558870_6 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000005976 241.0
HKD1_k127_2558870_7 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000009629 239.0
HKD1_k127_2558870_8 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000001714 223.0
HKD1_k127_2558870_9 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000000003451 169.0
HKD1_k127_2584136_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 8.457e-209 677.0
HKD1_k127_2584136_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 421.0
HKD1_k127_2584136_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 330.0
HKD1_k127_2584136_3 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 334.0
HKD1_k127_2584136_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000004124 237.0
HKD1_k127_2584136_5 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000002628 183.0
HKD1_k127_2584136_6 response regulator - - - 0.000000000000000000000000001524 116.0
HKD1_k127_2584136_7 Histidine kinase - - - 0.000000000000000000001964 109.0
HKD1_k127_263015_0 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 521.0
HKD1_k127_263015_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 514.0
HKD1_k127_263015_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 329.0
HKD1_k127_263015_3 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000003992 186.0
HKD1_k127_263015_4 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000000000000000003305 133.0
HKD1_k127_263015_5 cyclic nucleotide binding K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000437 102.0
HKD1_k127_263015_7 PFAM Forkhead-associated protein - - - 0.000000006974 66.0
HKD1_k127_263015_8 DnaJ-class molecular chaperone with C-terminal Zn finger domain K05516 - - 0.000001619 61.0
HKD1_k127_2645225_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 396.0
HKD1_k127_2645225_1 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000004598 256.0
HKD1_k127_2691729_0 Pirin C-terminal cupin domain K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 504.0
HKD1_k127_2691729_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 388.0
HKD1_k127_2691729_10 PFAM FecR protein - - - 0.000000001332 72.0
HKD1_k127_2691729_2 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 328.0
HKD1_k127_2691729_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 321.0
HKD1_k127_2691729_4 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001498 276.0
HKD1_k127_2691729_5 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001032 239.0
HKD1_k127_2691729_6 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000001645 223.0
HKD1_k127_2691729_7 NAD(P)H-dependent FMN reductase K00299 - 1.5.1.38 0.0000000000000000000000000000000000000000378 169.0
HKD1_k127_2691729_8 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000000003396 142.0
HKD1_k127_2691729_9 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000002827 134.0
HKD1_k127_2693381_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 398.0
HKD1_k127_2693381_1 PFAM amidohydrolase K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000001881 253.0
HKD1_k127_2693381_2 PDGLE domain K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000001113 241.0
HKD1_k127_2693381_3 YhhN family - - - 0.00000000000000000000000000000827 135.0
HKD1_k127_2693381_4 Cobalt ABC transporter K02008 - - 0.000000000000000000000007786 109.0
HKD1_k127_2693381_5 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.000000000000000000006025 105.0
HKD1_k127_2693381_6 long-chain fatty acid transporting porin activity K06076 - - 0.0001753 53.0
HKD1_k127_277514_0 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 510.0
HKD1_k127_277514_1 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000003219 169.0
HKD1_k127_277514_2 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000004945 141.0
HKD1_k127_277514_3 - - - - 0.0000000000000000000005891 98.0
HKD1_k127_2781104_0 Orn/Lys/Arg decarboxylase, N-terminal domain K01581 - 4.1.1.17 0.0 1136.0
HKD1_k127_2781104_1 PFAM Orn Lys Arg decarboxylase major region K01582,K01584 - 4.1.1.18,4.1.1.19 0.0 1047.0
HKD1_k127_2781104_2 Amino acid permease K03756,K03759 - - 9.368e-227 708.0
HKD1_k127_2781104_3 COG NOG10142 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 524.0
HKD1_k127_2781104_4 Zn_pept - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 436.0
HKD1_k127_2781104_5 Amino acid permease K03756,K03759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 430.0
HKD1_k127_2781104_6 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003565 274.0
HKD1_k127_2781104_7 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000005386 220.0
HKD1_k127_2910827_0 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000001055 231.0
HKD1_k127_2910827_1 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000000000000005694 133.0
HKD1_k127_2910827_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000003 87.0
HKD1_k127_2910827_3 RNA-binding protein - - - 0.000000000000000004171 94.0
HKD1_k127_2910827_4 serine threonine protein kinase K12132 - 2.7.11.1 0.0002915 50.0
HKD1_k127_3024010_0 Belongs to the ClpA ClpB family K03696 - - 1.221e-265 844.0
HKD1_k127_3024010_1 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 2.532e-219 709.0
HKD1_k127_3024010_10 Vitamin K epoxide reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 357.0
HKD1_k127_3024010_11 Surface antigen variable number K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 349.0
HKD1_k127_3024010_12 PFAM ABC transporter related K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 314.0
HKD1_k127_3024010_13 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003322 273.0
HKD1_k127_3024010_14 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001425 261.0
HKD1_k127_3024010_15 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000004237 243.0
HKD1_k127_3024010_16 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000000000000000003065 234.0
HKD1_k127_3024010_17 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000000000000000000000000000001836 223.0
HKD1_k127_3024010_18 - - - - 0.0000000000000000000000000000000000000000000000000000000007248 228.0
HKD1_k127_3024010_19 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000001667 220.0
HKD1_k127_3024010_2 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 1.262e-202 647.0
HKD1_k127_3024010_20 TIGRFAM FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000000002063 216.0
HKD1_k127_3024010_21 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000003993 200.0
HKD1_k127_3024010_22 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000001736 202.0
HKD1_k127_3024010_23 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000744 173.0
HKD1_k127_3024010_24 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000001947 184.0
HKD1_k127_3024010_25 spore germination K03298 - - 0.00000000000000000000000000000000000000001018 164.0
HKD1_k127_3024010_26 LppP/LprE lipoprotein - - - 0.00000000000000000000000000000000000000001126 177.0
HKD1_k127_3024010_27 Pfam:TPM K08988 - - 0.000000000000000000000000000000000007609 156.0
HKD1_k127_3024010_28 chain release factor K15034 - - 0.000000000000000000000000000000005529 132.0
HKD1_k127_3024010_29 SUF system FeS assembly protein K04488 - - 0.00000000000000000000000000000001937 132.0
HKD1_k127_3024010_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 572.0
HKD1_k127_3024010_30 - - - - 0.00000000000000000000000000001974 120.0
HKD1_k127_3024010_31 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000004752 124.0
HKD1_k127_3024010_32 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000001035 114.0
HKD1_k127_3024010_33 Transcriptional regulator - - - 0.0000000000000000000000008516 110.0
HKD1_k127_3024010_34 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000001433 118.0
HKD1_k127_3024010_35 family UPF0029 - - - 0.00000000000000000000002687 104.0
HKD1_k127_3024010_36 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000001099 111.0
HKD1_k127_3024010_37 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000008082 106.0
HKD1_k127_3024010_38 metal-sulfur cluster biosynthetic enzyme - - - 0.00000000000000000001413 101.0
HKD1_k127_3024010_39 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000006106 84.0
HKD1_k127_3024010_4 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 533.0
HKD1_k127_3024010_40 TIGRFAM TonB K03832 - - 0.0000000000000004646 88.0
HKD1_k127_3024010_41 - - - - 0.000000000000001583 89.0
HKD1_k127_3024010_42 photosystem II stabilization K02237,K02719 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.000000000000003565 89.0
HKD1_k127_3024010_43 ribonuclease BN K07058 - - 0.0000000000008337 81.0
HKD1_k127_3024010_44 acyl carrier protein - - - 0.000000001866 63.0
HKD1_k127_3024010_45 Protein of unknown function, DUF481 - - - 0.000000008144 68.0
HKD1_k127_3024010_46 snoRNA binding - - - 0.000002213 55.0
HKD1_k127_3024010_47 - - - - 0.00005183 54.0
HKD1_k127_3024010_48 Bacterial transcriptional activator domain - - - 0.0006068 47.0
HKD1_k127_3024010_5 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007977 519.0
HKD1_k127_3024010_6 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 471.0
HKD1_k127_3024010_7 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 447.0
HKD1_k127_3024010_8 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 434.0
HKD1_k127_3024010_9 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 415.0
HKD1_k127_3028575_0 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000005317 219.0
HKD1_k127_3028575_1 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000008542 199.0
HKD1_k127_3028575_2 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.0000000000000000001857 90.0
HKD1_k127_3028575_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000001197 90.0
HKD1_k127_3030287_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0 1318.0
HKD1_k127_3036284_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 541.0
HKD1_k127_3036284_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003457 269.0
HKD1_k127_3036284_2 - K01992 - - 0.0000000000000000000000000006129 128.0
HKD1_k127_3044642_0 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000001049 175.0
HKD1_k127_3044642_1 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000005788 126.0
HKD1_k127_3044642_2 Belongs to the glycosyl hydrolase 3 family - - - 0.0000000000000000000001128 112.0
HKD1_k127_3076162_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 2.768e-241 769.0
HKD1_k127_3076162_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 357.0
HKD1_k127_3076162_2 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009177 327.0
HKD1_k127_3076162_3 anaphase-promoting complex binding - - - 0.000000002726 63.0
HKD1_k127_3083699_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 565.0
HKD1_k127_3083699_1 PFAM Cys Met metabolism K01760,K01761 - 4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 452.0
HKD1_k127_3083699_2 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009499 272.0
HKD1_k127_3083699_3 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000009998 255.0
HKD1_k127_3083699_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000024 157.0
HKD1_k127_3089083_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 392.0
HKD1_k127_3089083_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008829 244.0
HKD1_k127_3089083_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000005942 103.0
HKD1_k127_3089083_3 Peptidase family M28 K19702 - 3.4.11.24 0.00000000000001505 88.0
HKD1_k127_3089083_4 peptidyl-tyrosine sulfation - - - 0.00000000002843 76.0
HKD1_k127_3112207_0 Male sterility protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 384.0
HKD1_k127_3112207_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 367.0
HKD1_k127_3112207_2 glycerone kinase activity K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 370.0
HKD1_k127_3112207_3 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000008372 108.0
HKD1_k127_3112207_4 Psort location CytoplasmicMembrane, score - - - 0.0002212 53.0
HKD1_k127_3116621_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000006647 142.0
HKD1_k127_3116621_1 domain, Protein - - - 0.0003549 51.0
HKD1_k127_3122798_0 Elongation factor G, domain IV K02355 - - 8.857e-200 647.0
HKD1_k127_3122798_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 587.0
HKD1_k127_3122798_11 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000002033 254.0
HKD1_k127_3122798_12 geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000000000000000000000000000128 238.0
HKD1_k127_3122798_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000002046 229.0
HKD1_k127_3122798_14 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000009442 220.0
HKD1_k127_3122798_15 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000003033 218.0
HKD1_k127_3122798_16 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000002808 198.0
HKD1_k127_3122798_17 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000000000000000000001166 192.0
HKD1_k127_3122798_18 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000001458 182.0
HKD1_k127_3122798_19 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000003406 174.0
HKD1_k127_3122798_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 590.0
HKD1_k127_3122798_20 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000001643 168.0
HKD1_k127_3122798_21 Squalene--hopene cyclase - - - 0.00000000000000000000000000000000000000000428 166.0
HKD1_k127_3122798_22 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000001647 151.0
HKD1_k127_3122798_23 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000003941 154.0
HKD1_k127_3122798_24 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000001808 143.0
HKD1_k127_3122798_25 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000003924 153.0
HKD1_k127_3122798_26 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000004762 142.0
HKD1_k127_3122798_27 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000006823 141.0
HKD1_k127_3122798_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000001235 144.0
HKD1_k127_3122798_29 Alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000002334 137.0
HKD1_k127_3122798_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 593.0
HKD1_k127_3122798_30 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000004631 139.0
HKD1_k127_3122798_31 DinB superfamily - - - 0.0000000000000000000000000000006123 130.0
HKD1_k127_3122798_32 Cold shock protein K03704 - - 0.0000000000000000000000000002249 116.0
HKD1_k127_3122798_33 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000001632 122.0
HKD1_k127_3122798_34 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000004553 114.0
HKD1_k127_3122798_35 Outer membrane lipoprotein - - - 0.000000000000000000000000335 120.0
HKD1_k127_3122798_36 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000009584 108.0
HKD1_k127_3122798_37 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000007536 109.0
HKD1_k127_3122798_38 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.00000000000000000000183 99.0
HKD1_k127_3122798_39 Smr domain - - - 0.00000000000000000002426 104.0
HKD1_k127_3122798_4 ATP-dependent helicase activity K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 419.0
HKD1_k127_3122798_40 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000001523 74.0
HKD1_k127_3122798_41 Forkhead associated domain - - - 0.000000000008377 75.0
HKD1_k127_3122798_42 - - - - 0.0000000004285 65.0
HKD1_k127_3122798_43 TonB C terminal K03832 - - 0.000000085 63.0
HKD1_k127_3122798_44 RDD family - - - 0.000003333 58.0
HKD1_k127_3122798_5 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 354.0
HKD1_k127_3122798_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 335.0
HKD1_k127_3122798_7 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 305.0
HKD1_k127_3122798_8 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 301.0
HKD1_k127_3122798_9 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005978 274.0
HKD1_k127_3144297_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 458.0
HKD1_k127_3144297_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 323.0
HKD1_k127_3144297_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 329.0
HKD1_k127_3144297_3 PFAM Nitroreductase - - - 0.000000000000001054 85.0
HKD1_k127_3144297_4 AIPR protein - - - 0.0001006 55.0
HKD1_k127_3163350_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 563.0
HKD1_k127_3184289_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 503.0
HKD1_k127_3184289_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 461.0
HKD1_k127_3184289_10 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000003346 175.0
HKD1_k127_3184289_11 HD domain - - - 0.00000000000000000000000000000000000000002094 173.0
HKD1_k127_3184289_12 Aldo/keto reductase family K19265 - - 0.0000000000000000000000000004259 116.0
HKD1_k127_3184289_13 - - - - 0.000000000001091 80.0
HKD1_k127_3184289_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 396.0
HKD1_k127_3184289_3 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 367.0
HKD1_k127_3184289_4 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 348.0
HKD1_k127_3184289_5 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 335.0
HKD1_k127_3184289_6 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 321.0
HKD1_k127_3184289_7 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001607 243.0
HKD1_k127_3184289_8 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000002954 246.0
HKD1_k127_3184289_9 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000002701 203.0
HKD1_k127_3191475_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 441.0
HKD1_k127_3191475_1 Outer membrane protein beta-barrel family K16087 - - 0.000000000000000000000000000000000000000000000000000000000002727 229.0
HKD1_k127_3191475_2 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000001518 73.0
HKD1_k127_3195930_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1060.0
HKD1_k127_3195930_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.02e-204 647.0
HKD1_k127_3195930_2 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 327.0
HKD1_k127_3195930_3 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 313.0
HKD1_k127_3195930_4 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000005482 201.0
HKD1_k127_3195930_5 Glycosyltransferase like family 2 K20444 - - 0.00000000000000000000000000005187 129.0
HKD1_k127_3195930_6 DinB family - - - 0.000000000000000000000001627 109.0
HKD1_k127_3196971_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 615.0
HKD1_k127_3196971_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 434.0
HKD1_k127_3196971_10 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000272 106.0
HKD1_k127_3196971_11 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.0000000000000000000002243 108.0
HKD1_k127_3196971_12 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.0000000000000001354 83.0
HKD1_k127_3196971_13 peptidase M36 - - - 0.000005587 58.0
HKD1_k127_3196971_14 FR47-like protein - - - 0.00001466 55.0
HKD1_k127_3196971_15 Transcriptional regulator - - - 0.00005315 55.0
HKD1_k127_3196971_2 elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 359.0
HKD1_k127_3196971_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002676 284.0
HKD1_k127_3196971_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001352 269.0
HKD1_k127_3196971_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000002606 263.0
HKD1_k127_3196971_6 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000007562 228.0
HKD1_k127_3196971_7 DNA polymerase beta thumb K02347 - - 0.0000000000000000000000000000000002403 148.0
HKD1_k127_3196971_8 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000001358 135.0
HKD1_k127_3196971_9 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.0000000000000000000000004274 112.0
HKD1_k127_3203258_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 434.0
HKD1_k127_3203258_1 Cyclic nucleotide-monophosphate binding domain K21564 - - 0.00000000000000000000000000000000000000000000000000000000000000001045 233.0
HKD1_k127_3203258_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000007517 197.0
HKD1_k127_3203258_3 Binds the 23S rRNA K02909 - - 0.000000000000000000000000105 108.0
HKD1_k127_3203258_4 - - - - 0.00000000006435 64.0
HKD1_k127_32175_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 394.0
HKD1_k127_32175_1 COG0644 Dehydrogenases (flavoproteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000009479 247.0
HKD1_k127_32175_2 Aminotransferase, class V - - - 0.000000000000000000000000000000000000000000000000000000000003858 234.0
HKD1_k127_32175_3 ABC transporter, transmembrane K18890 - - 0.000000000000000000000000000000003845 139.0
HKD1_k127_32175_4 Protein of unknown function, DUF547 - - - 0.00007066 54.0
HKD1_k127_323230_0 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 429.0
HKD1_k127_323230_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 316.0
HKD1_k127_323230_2 oxidoreductase K00334 - 1.6.5.3 0.00000000000000000000000000000000000005126 150.0
HKD1_k127_323230_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000004591 95.0
HKD1_k127_3235579_0 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.00000000000000000000000000000000000000000000000001614 192.0
HKD1_k127_3235579_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000004769 94.0
HKD1_k127_3235579_2 involved in lipopolysaccharide - - - 0.000000003721 57.0
HKD1_k127_3264984_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 524.0
HKD1_k127_3264984_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 411.0
HKD1_k127_3264984_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 395.0
HKD1_k127_3264984_3 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 309.0
HKD1_k127_3264984_4 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001548 280.0
HKD1_k127_3264984_5 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000001576 228.0
HKD1_k127_3264984_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000007873 240.0
HKD1_k127_3264984_7 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000008684 211.0
HKD1_k127_3264984_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000005874 117.0
HKD1_k127_3272771_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1298.0
HKD1_k127_3272771_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 612.0
HKD1_k127_3272771_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 436.0
HKD1_k127_3272771_3 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000001133 149.0
HKD1_k127_3272771_4 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000003786 140.0
HKD1_k127_3273106_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 355.0
HKD1_k127_3273106_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 314.0
HKD1_k127_3273106_2 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 302.0
HKD1_k127_3273106_3 Pfam:Arch_ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003729 286.0
HKD1_k127_3273106_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000001409 213.0
HKD1_k127_3273106_5 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000004441 119.0
HKD1_k127_3336362_0 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000001062 262.0
HKD1_k127_3336362_1 Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000003089 248.0
HKD1_k127_3336548_0 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 487.0
HKD1_k127_3336548_1 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 316.0
HKD1_k127_3336548_2 cytochrome c - - - 0.000000000000000000000000000008555 126.0
HKD1_k127_3336548_3 Pfam Polysulphide reductase, NrfD - - - 0.0000000000000000000000000581 121.0
HKD1_k127_3336548_4 Protein of unknown function (DUF3341) - - - 0.00000000003912 70.0
HKD1_k127_3336548_5 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000005381 66.0
HKD1_k127_3370715_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1258.0
HKD1_k127_3370715_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 364.0
HKD1_k127_3370715_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000006789 88.0
HKD1_k127_3372010_0 5' nucleotidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 599.0
HKD1_k127_3372010_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 519.0
HKD1_k127_3372010_2 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 488.0
HKD1_k127_3372010_3 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 469.0
HKD1_k127_3372010_4 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009989 256.0
HKD1_k127_3372010_5 Domain of Unknown Function with PDB structure (DUF3858) - - - 0.00000000000000000000000000002805 137.0
HKD1_k127_3372010_6 von Willebrand factor, type A K07114 - - 0.0000000003465 68.0
HKD1_k127_3372010_7 - - - - 0.000000001316 71.0
HKD1_k127_3433940_0 Sugar phosphate permease K02445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 572.0
HKD1_k127_3433940_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.00000000000000000000000000000000000000002189 165.0
HKD1_k127_3433940_2 creatininase K01470 - 3.5.2.10 0.000000001022 61.0
HKD1_k127_3457483_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 295.0
HKD1_k127_3457483_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001187 266.0
HKD1_k127_3457483_2 Beta-lactamase superfamily domain - - - 0.000000000000000000001913 106.0
HKD1_k127_3488236_0 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 563.0
HKD1_k127_3488236_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 326.0
HKD1_k127_3488236_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000001702 156.0
HKD1_k127_3489823_0 Serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 443.0
HKD1_k127_3489823_1 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000305 250.0
HKD1_k127_3489823_2 - - - - 0.00000004684 57.0
HKD1_k127_3489823_3 - - - - 0.00001595 57.0
HKD1_k127_3489823_4 ParB-like nuclease domain K03497 - - 0.00003723 46.0
HKD1_k127_3534268_0 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000199 236.0
HKD1_k127_3534268_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000001275 102.0
HKD1_k127_3534268_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000001653 77.0
HKD1_k127_3534268_3 - - - - 0.0004367 49.0
HKD1_k127_3579900_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 572.0
HKD1_k127_3579900_1 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000000000000000000000000000000003218 228.0
HKD1_k127_3579900_2 thiamine pyrophosphokinase K00949 - 2.7.6.2 0.000000000000000004843 92.0
HKD1_k127_3622232_0 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 1.13e-234 739.0
HKD1_k127_3622232_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 4.277e-225 720.0
HKD1_k127_3622232_10 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000002535 239.0
HKD1_k127_3622232_11 Polysaccharide export protein K01991,K20988 - - 0.00000000000000000000000000000000000000000000000000000000000124 221.0
HKD1_k127_3622232_12 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000001365 218.0
HKD1_k127_3622232_13 capsular polysaccharide biosynthesis protein K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000001244 173.0
HKD1_k127_3622232_14 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.00000000000000000000000000000000002069 154.0
HKD1_k127_3622232_15 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000001633 128.0
HKD1_k127_3622232_16 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000000000000000000303 133.0
HKD1_k127_3622232_17 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000002693 119.0
HKD1_k127_3622232_18 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000004164 121.0
HKD1_k127_3622232_19 O-antigen ligase like membrane protein - - - 0.000000000000000000000000164 122.0
HKD1_k127_3622232_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.868e-198 647.0
HKD1_k127_3622232_20 Ribosome-binding factor A - - - 0.00000000000000002964 89.0
HKD1_k127_3622232_21 succinate dehydrogenase activity K00242,K00246 - - 0.0000000000006978 73.0
HKD1_k127_3622232_22 Protein conserved in bacteria K09764 - - 0.0000000006086 64.0
HKD1_k127_3622232_3 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 538.0
HKD1_k127_3622232_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 389.0
HKD1_k127_3622232_5 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 399.0
HKD1_k127_3622232_6 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 374.0
HKD1_k127_3622232_7 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001259 287.0
HKD1_k127_3622232_8 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002015 270.0
HKD1_k127_3622232_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000008888 252.0
HKD1_k127_3679282_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 314.0
HKD1_k127_3679282_1 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000004382 207.0
HKD1_k127_3679282_2 - - - - 0.0000000003898 68.0
HKD1_k127_3679282_3 - - - - 0.00000001053 67.0
HKD1_k127_3679282_4 - - - - 0.00000002971 64.0
HKD1_k127_3679282_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.0002845 52.0
HKD1_k127_3870020_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 321.0
HKD1_k127_3870020_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000002243 121.0
HKD1_k127_3925431_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 340.0
HKD1_k127_3925431_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 317.0
HKD1_k127_3925431_10 Glycosyl transferase, family 2 - - - 0.0000000000000003774 90.0
HKD1_k127_3925431_2 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001995 281.0
HKD1_k127_3925431_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008124 277.0
HKD1_k127_3925431_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000004145 244.0
HKD1_k127_3925431_5 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000005474 196.0
HKD1_k127_3925431_6 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000002608 144.0
HKD1_k127_3925431_7 PAS domain K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000001432 153.0
HKD1_k127_3925431_8 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000000000000000000000009019 117.0
HKD1_k127_3925431_9 Pfam AhpC TSA family - - - 0.0000000000000000000009681 104.0
HKD1_k127_3932_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1058.0
HKD1_k127_3932_1 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 2.27e-243 772.0
HKD1_k127_3932_10 DRTGG domain - - - 0.00000004236 59.0
HKD1_k127_3932_2 Fe-S cluster domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 319.0
HKD1_k127_3932_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000007115 181.0
HKD1_k127_3932_4 Thioredoxin-like [2Fe-2S] ferredoxin K05586 - 1.6.5.3 0.00000000000000000000000000000000000000000002328 166.0
HKD1_k127_3932_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000293 157.0
HKD1_k127_3932_6 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000003347 141.0
HKD1_k127_3932_7 DRTGG domain - - - 0.000000000000000000001487 103.0
HKD1_k127_3932_9 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000661 61.0
HKD1_k127_394227_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1631.0
HKD1_k127_394227_1 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 3.575e-212 684.0
HKD1_k127_394227_2 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 418.0
HKD1_k127_394227_3 phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000003159 228.0
HKD1_k127_394227_4 - - - - 0.000000000000002453 82.0
HKD1_k127_394227_5 Acetyltransferase (GNAT) domain - - - 0.000000000000004783 87.0
HKD1_k127_4027874_0 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 504.0
HKD1_k127_4027874_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 402.0
HKD1_k127_4027874_10 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.000000000000000000000002542 114.0
HKD1_k127_4027874_11 Protein of unknown function (DUF2721) - - - 0.00000000000000005848 94.0
HKD1_k127_4027874_2 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001737 273.0
HKD1_k127_4027874_3 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000005658 256.0
HKD1_k127_4027874_4 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001423 237.0
HKD1_k127_4027874_5 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000001124 232.0
HKD1_k127_4027874_6 deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000001011 214.0
HKD1_k127_4027874_7 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000001609 200.0
HKD1_k127_4027874_8 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000001125 171.0
HKD1_k127_4027874_9 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000001399 137.0
HKD1_k127_4038366_0 Outer membrane protein beta-barrel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 347.0
HKD1_k127_4038366_1 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 318.0
HKD1_k127_4040358_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 564.0
HKD1_k127_4040358_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 432.0
HKD1_k127_4040358_10 Fumarase C-terminus K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000002052 252.0
HKD1_k127_4040358_11 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001888 246.0
HKD1_k127_4040358_12 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000008964 227.0
HKD1_k127_4040358_13 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000003969 161.0
HKD1_k127_4040358_14 NTPase K06928 - 3.6.1.15 0.0000000000000000000000000000000000005091 147.0
HKD1_k127_4040358_15 AAA domain - - - 0.000000000000000000000000000000000003863 143.0
HKD1_k127_4040358_16 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000157 136.0
HKD1_k127_4040358_17 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000002233 138.0
HKD1_k127_4040358_18 PFAM 4Fe-4S ferredoxin, iron-sulfur binding K00176 - 1.2.7.3 0.00000000000000000000721 106.0
HKD1_k127_4040358_19 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000002787 67.0
HKD1_k127_4040358_2 Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K07806 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:0099620,GO:1901363 2.6.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 422.0
HKD1_k127_4040358_20 SNARE associated Golgi protein - - - 0.0000001626 53.0
HKD1_k127_4040358_3 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 402.0
HKD1_k127_4040358_4 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 384.0
HKD1_k127_4040358_5 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 370.0
HKD1_k127_4040358_6 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 322.0
HKD1_k127_4040358_7 Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K01784,K10011 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004554 298.0
HKD1_k127_4040358_8 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008292 266.0
HKD1_k127_4040358_9 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000201 259.0
HKD1_k127_4044887_0 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 598.0
HKD1_k127_4044887_1 Proton-conducting membrane transporter K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 455.0
HKD1_k127_4044887_2 Proton-conducting membrane transporter K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 381.0
HKD1_k127_4044887_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K12139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 330.0
HKD1_k127_4044887_4 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005441 254.0
HKD1_k127_4044887_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000007471 228.0
HKD1_k127_4044887_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K12143,K15831 - - 0.0000000000000000000000000000000000000000000002628 171.0
HKD1_k127_4044887_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L - - - 0.00000000000000000000000000000000000002109 152.0
HKD1_k127_4044887_8 cheY-homologous receiver domain K07658 - - 0.00000000000000000000000000002967 125.0
HKD1_k127_4044887_9 Histidine kinase K15011 - 2.7.13.3 0.0004005 46.0
HKD1_k127_4049291_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 1.983e-209 668.0
HKD1_k127_4049291_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 359.0
HKD1_k127_4049291_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 326.0
HKD1_k127_4049291_3 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002668 258.0
HKD1_k127_4049291_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001195 239.0
HKD1_k127_4049291_5 acetyltransferase - - - 0.00000000000000000000000000000000000006858 156.0
HKD1_k127_4049291_6 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000003526 117.0
HKD1_k127_4049291_7 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000005315 96.0
HKD1_k127_4049291_8 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000006816 87.0
HKD1_k127_4049291_9 Lrp/AsnC ligand binding domain - - - 0.000000000000003436 78.0
HKD1_k127_4069449_0 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 1.004e-238 750.0
HKD1_k127_4069449_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 507.0
HKD1_k127_4069449_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000007235 84.0
HKD1_k127_4069449_11 Domain of unknown function (DUF4388) - - - 0.0000000000003659 79.0
HKD1_k127_4069449_12 PFAM Outer membrane efflux protein - - - 0.000000005372 69.0
HKD1_k127_4069449_2 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 452.0
HKD1_k127_4069449_3 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 413.0
HKD1_k127_4069449_4 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 311.0
HKD1_k127_4069449_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000002379 245.0
HKD1_k127_4069449_6 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000328 250.0
HKD1_k127_4069449_7 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000003755 168.0
HKD1_k127_4069449_8 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000002926 121.0
HKD1_k127_4069449_9 Regulatory protein, FmdB - - - 0.000000000000000000000327 99.0
HKD1_k127_4070301_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 630.0
HKD1_k127_4070301_1 Phospholipase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 557.0
HKD1_k127_4070301_10 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.000000000000000000000000000000000000000000000000609 184.0
HKD1_k127_4070301_11 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000004238 173.0
HKD1_k127_4070301_12 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000001055 168.0
HKD1_k127_4070301_13 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000001075 159.0
HKD1_k127_4070301_14 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000002136 164.0
HKD1_k127_4070301_15 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000001003 157.0
HKD1_k127_4070301_16 YsiA-like protein, C-terminal region K13770 - - 0.00000000000000000000000000000000000002188 152.0
HKD1_k127_4070301_17 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000002765 116.0
HKD1_k127_4070301_18 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000061 96.0
HKD1_k127_4070301_19 Domain of unknown function (DUF4440) - - - 0.0000003382 61.0
HKD1_k127_4070301_2 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 503.0
HKD1_k127_4070301_20 - - - - 0.0000004346 54.0
HKD1_k127_4070301_3 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 445.0
HKD1_k127_4070301_4 Amino-transferase class IV K00826 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0006082,GO:0006464,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018065,GO:0018193,GO:0018205,GO:0018272,GO:0018352,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0036211,GO:0040007,GO:0043094,GO:0043102,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071265,GO:0071267,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 366.0
HKD1_k127_4070301_5 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002246 293.0
HKD1_k127_4070301_6 Competence-damaged protein K03742,K03743 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000001838 265.0
HKD1_k127_4070301_7 Protein export membrane protein K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009671 269.0
HKD1_k127_4070301_8 NIF3 (NGG1p interacting factor 3) K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000001237 243.0
HKD1_k127_4070301_9 beta-lactamase superfamily II K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000005572 220.0
HKD1_k127_4135244_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 528.0
HKD1_k127_4135244_1 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000007033 68.0
HKD1_k127_4135244_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000001097 66.0
HKD1_k127_4141509_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 4.63e-286 916.0
HKD1_k127_4141509_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 1.659e-220 694.0
HKD1_k127_4141509_10 THUMP K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 325.0
HKD1_k127_4141509_11 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 306.0
HKD1_k127_4141509_12 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 291.0
HKD1_k127_4141509_13 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000006171 247.0
HKD1_k127_4141509_14 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000003379 233.0
HKD1_k127_4141509_15 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000001384 225.0
HKD1_k127_4141509_16 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000001579 215.0
HKD1_k127_4141509_17 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000004968 197.0
HKD1_k127_4141509_18 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000137 196.0
HKD1_k127_4141509_19 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000001803 191.0
HKD1_k127_4141509_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.268e-211 669.0
HKD1_k127_4141509_20 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000004044 180.0
HKD1_k127_4141509_21 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000009326 154.0
HKD1_k127_4141509_22 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000008749 136.0
HKD1_k127_4141509_23 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000339 139.0
HKD1_k127_4141509_24 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.0000000000000000000000000002692 120.0
HKD1_k127_4141509_25 PFAM phosphoryl transfer system HPr K11189 - - 0.000000000000000000000008473 103.0
HKD1_k127_4141509_26 - - - - 0.00000000000000000000001902 113.0
HKD1_k127_4141509_27 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000309 100.0
HKD1_k127_4141509_28 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000006122 100.0
HKD1_k127_4141509_29 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000007929 92.0
HKD1_k127_4141509_3 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009387 597.0
HKD1_k127_4141509_30 Thioesterase superfamily - - - 0.0000000000000007189 84.0
HKD1_k127_4141509_31 - - - - 0.000000000000001215 86.0
HKD1_k127_4141509_32 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000000284 78.0
HKD1_k127_4141509_34 Domain of unknown function (DUF4115) K15539 - - 0.0000000002104 71.0
HKD1_k127_4141509_35 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.0003671 54.0
HKD1_k127_4141509_4 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 441.0
HKD1_k127_4141509_5 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000861 441.0
HKD1_k127_4141509_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 372.0
HKD1_k127_4141509_7 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 359.0
HKD1_k127_4141509_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 351.0
HKD1_k127_4141509_9 Permease, YjgP YjgQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 338.0
HKD1_k127_4144281_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1762.0
HKD1_k127_4144281_1 Molybdopterin oxidoreductase, iron-sulfur binding subunit K00184 - - 6.977e-302 956.0
HKD1_k127_4144281_10 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 381.0
HKD1_k127_4144281_11 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 331.0
HKD1_k127_4144281_12 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 292.0
HKD1_k127_4144281_13 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 290.0
HKD1_k127_4144281_14 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001269 269.0
HKD1_k127_4144281_15 COGs COG0790 FOG TPR repeat SEL1 subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001336 226.0
HKD1_k127_4144281_16 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000002654 211.0
HKD1_k127_4144281_17 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000003472 143.0
HKD1_k127_4144281_18 - - - - 0.0000000000000000000000000000001662 133.0
HKD1_k127_4144281_19 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000003671 139.0
HKD1_k127_4144281_2 Polysulphide reductase K00185 - - 2.217e-216 684.0
HKD1_k127_4144281_20 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.000000000000000000000005466 119.0
HKD1_k127_4144281_21 - - - - 0.0000009537 55.0
HKD1_k127_4144281_22 Belongs to the 'phage' integrase family - - - 0.00006612 46.0
HKD1_k127_4144281_3 Peptidase S46 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 585.0
HKD1_k127_4144281_4 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 507.0
HKD1_k127_4144281_5 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 430.0
HKD1_k127_4144281_6 PFAM Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 451.0
HKD1_k127_4144281_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 402.0
HKD1_k127_4144281_8 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 405.0
HKD1_k127_4144281_9 2,3-bisphosphoglycerate-independent phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 385.0
HKD1_k127_4153032_0 Major Facilitator Superfamily - - - 1.962e-199 632.0
HKD1_k127_4153032_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009952 499.0
HKD1_k127_4153032_10 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000166 165.0
HKD1_k127_4153032_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000002396 149.0
HKD1_k127_4153032_12 Iron-sulfur cluster insertion protein ErpA K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:1901564 - 0.000000000000000000000000000000001881 132.0
HKD1_k127_4153032_13 PDZ domain - - - 0.0000000000000004444 92.0
HKD1_k127_4153032_14 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000001414 81.0
HKD1_k127_4153032_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 398.0
HKD1_k127_4153032_3 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 331.0
HKD1_k127_4153032_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 311.0
HKD1_k127_4153032_5 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004991 278.0
HKD1_k127_4153032_6 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007213 250.0
HKD1_k127_4153032_7 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000001616 256.0
HKD1_k127_4153032_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000006406 227.0
HKD1_k127_4153032_9 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000000000000000001133 186.0
HKD1_k127_4204021_0 ATPase (AAA superfamily K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002925 278.0
HKD1_k127_4204021_1 Protein of unknown function (DUF2490) - - - 0.000005616 57.0
HKD1_k127_4206466_0 aconitate hydratase K01681 - 4.2.1.3 2.042e-317 990.0
HKD1_k127_4206466_1 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 441.0
HKD1_k127_4206466_10 Phospholipid methyltransferase - - - 0.00000000001233 70.0
HKD1_k127_4206466_11 PFAM PKD domain containing protein - - - 0.00000000003994 77.0
HKD1_k127_4206466_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000004396 68.0
HKD1_k127_4206466_13 PFAM PKD domain containing protein - - - 0.0000000006297 72.0
HKD1_k127_4206466_14 Putative adhesin - - - 0.0000001398 63.0
HKD1_k127_4206466_2 symporter activity K11928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 434.0
HKD1_k127_4206466_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 299.0
HKD1_k127_4206466_4 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008031 263.0
HKD1_k127_4206466_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000001659 225.0
HKD1_k127_4206466_6 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000001366 183.0
HKD1_k127_4206466_7 PFAM CBS domain containing protein K07168 - - 0.000000000000000000000000000000001441 134.0
HKD1_k127_4206466_8 Domain of unknown function (DUF4340) - - - 0.0000000000000000001752 104.0
HKD1_k127_4206466_9 Cellulose 1,4-beta-cellobiosidase - - - 0.00000000000006903 86.0
HKD1_k127_4218169_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 587.0
HKD1_k127_4218169_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 533.0
HKD1_k127_4218169_2 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 362.0
HKD1_k127_4218169_4 Surface antigen K07277 - - 0.000000000000000000000000000000000006505 153.0
HKD1_k127_4218169_5 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000002401 131.0
HKD1_k127_4218169_6 - - - - 0.00000000000005606 86.0
HKD1_k127_4218169_7 Peptidase M56 - - - 0.000000006271 68.0
HKD1_k127_4218169_8 Protein of unknown function (DUF2723) - - - 0.00003085 57.0
HKD1_k127_424058_0 Predicted Permease Membrane Region K07085 - - 1.392e-207 659.0
HKD1_k127_424058_1 Inorganic ion transport and metabolism K03319 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 428.0
HKD1_k127_424058_2 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000007898 187.0
HKD1_k127_4320492_0 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000008113 156.0
HKD1_k127_4320492_1 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000004003 106.0
HKD1_k127_4420251_0 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K00131 - 1.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 580.0
HKD1_k127_4420251_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 449.0
HKD1_k127_4420251_10 PFAM peptidase - - - 0.0000000000000000000000000000000000001429 160.0
HKD1_k127_4420251_11 Thiamine-binding protein - - - 0.00000000000000000000000000000000008583 135.0
HKD1_k127_4420251_12 COG1012 NAD-dependent aldehyde dehydrogenases K00131 - 1.2.1.9 0.000000000000000000004142 96.0
HKD1_k127_4420251_14 ACT domain K09707 - - 0.00000004942 60.0
HKD1_k127_4420251_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 285.0
HKD1_k127_4420251_3 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007696 282.0
HKD1_k127_4420251_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008401 287.0
HKD1_k127_4420251_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000201 215.0
HKD1_k127_4420251_6 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000005454 205.0
HKD1_k127_4420251_7 - - - - 0.0000000000000000000000000000000000000000000000002835 181.0
HKD1_k127_4420251_8 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000002432 181.0
HKD1_k127_4420251_9 Purple acid Phosphatase, N-terminal domain - - - 0.000000000000000000000000000000000000000000004757 180.0
HKD1_k127_4424119_0 PFAM Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 388.0
HKD1_k127_4424119_1 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 302.0
HKD1_k127_4424119_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000003217 146.0
HKD1_k127_4424119_3 electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.0000000000000000000000000000000003835 136.0
HKD1_k127_4424119_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000000001937 99.0
HKD1_k127_4437055_0 Sugar ABC transporter permease K10109,K15770,K15771 - - 1.015e-196 637.0
HKD1_k127_4437055_1 Binding-protein-dependent transport system inner membrane component K10110,K15772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 387.0
HKD1_k127_4437055_2 Bacterial extracellular solute-binding protein K10108,K15770 - - 0.0000000000000000000000000000000004218 133.0
HKD1_k127_4445574_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001163 275.0
HKD1_k127_4506544_0 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 617.0
HKD1_k127_4506544_1 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 452.0
HKD1_k127_4506544_2 Alanine dehydrogenase/PNT, C-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 401.0
HKD1_k127_4506544_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000034 116.0
HKD1_k127_4506544_4 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000477 111.0
HKD1_k127_4507360_0 transporter, DctM subunit K11690 - - 1.906e-216 690.0
HKD1_k127_4507360_1 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 376.0
HKD1_k127_4507360_2 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 317.0
HKD1_k127_4507360_4 Rhomboid family - - - 0.0000000000000000000002634 99.0
HKD1_k127_4508326_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 3.934e-258 812.0
HKD1_k127_4508326_1 Universal stress protein - - - 0.000000000000000000000000000005216 132.0
HKD1_k127_453846_0 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000121 297.0
HKD1_k127_4658915_0 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007574 285.0
HKD1_k127_4658915_1 - - - - 0.0000000000000000000000000000000000000000000000000000000002575 207.0
HKD1_k127_4658915_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000004394 199.0
HKD1_k127_4658915_3 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000000000000000000001964 208.0
HKD1_k127_4658915_4 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000002445 141.0
HKD1_k127_4658915_5 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000002527 103.0
HKD1_k127_4664497_0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K03796 - - 0.00000000000000000000000000000000000000000000000000000000000000000002326 244.0
HKD1_k127_4664497_1 PFAM Cytochrome b b6 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006343 245.0
HKD1_k127_4664497_2 Ion channel - - - 0.00000000000000004378 93.0
HKD1_k127_4664497_3 Putative MetA-pathway of phenol degradation - - - 0.000000000000008453 78.0
HKD1_k127_468264_0 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 580.0
HKD1_k127_468264_1 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 404.0
HKD1_k127_468264_10 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000006015 140.0
HKD1_k127_468264_11 oxidase subunit K08738 - - 0.0000000000000000000000000193 119.0
HKD1_k127_468264_12 Protein of unknown function (DUF4013) - - - 0.00001877 56.0
HKD1_k127_468264_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 337.0
HKD1_k127_468264_3 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 352.0
HKD1_k127_468264_4 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003046 278.0
HKD1_k127_468264_5 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000001162 234.0
HKD1_k127_468264_6 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000007282 235.0
HKD1_k127_468264_7 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000001862 235.0
HKD1_k127_468264_8 Putative molybdenum carrier - - - 0.00000000000000000000000000000000000000000000000004152 190.0
HKD1_k127_468264_9 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000001133 174.0
HKD1_k127_471412_0 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 401.0
HKD1_k127_471412_1 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 295.0
HKD1_k127_471412_2 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000002196 220.0
HKD1_k127_471412_3 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000001691 196.0
HKD1_k127_471412_4 Glycosyltransferase, group 1 family protein - - - 0.000000000000000000000000000000007849 143.0
HKD1_k127_4794817_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009296 580.0
HKD1_k127_4794817_1 coagulation factor 5 8 type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 490.0
HKD1_k127_4794817_2 ABC transporter substrate-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 451.0
HKD1_k127_4794817_3 transmembrane transport K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 374.0
HKD1_k127_4794817_4 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 329.0
HKD1_k127_4794817_5 Carboxypeptidase regulatory-like domain - - - 0.000002392 52.0
HKD1_k127_4929843_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 627.0
HKD1_k127_4929843_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 499.0
HKD1_k127_494770_0 Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 468.0
HKD1_k127_494770_1 PFAM Cytochrome c assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000004123 220.0
HKD1_k127_494770_2 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000005767 173.0
HKD1_k127_494770_3 CcmB protein K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.00000000000000000000000000000000000003224 154.0
HKD1_k127_494770_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000004026 121.0
HKD1_k127_494770_5 Protein of unknown function (DUF2723) - - - 0.0000000001788 74.0
HKD1_k127_4977819_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000009195 218.0
HKD1_k127_4977819_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000002378 166.0
HKD1_k127_4977819_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000002108 113.0
HKD1_k127_5040783_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 312.0
HKD1_k127_5040783_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000009776 203.0
HKD1_k127_5040783_10 antisigma factor binding - - - 0.00000000000000008439 85.0
HKD1_k127_5040783_11 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000000002919 84.0
HKD1_k127_5040783_12 Acetyltransferase (GNAT) domain - - - 0.0000000000000003989 90.0
HKD1_k127_5040783_13 PFAM Glycosyl transferases group 1 - - - 0.0000000000186 76.0
HKD1_k127_5040783_14 PFAM Outer membrane protein transport protein (OMPP1 FadL TodX) K06076 - - 0.00000000006293 64.0
HKD1_k127_5040783_15 Bacterial membrane protein, YfhO - - - 0.000001293 62.0
HKD1_k127_5040783_16 PFAM PEGA domain - - - 0.000001944 59.0
HKD1_k127_5040783_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000003424 179.0
HKD1_k127_5040783_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000001517 164.0
HKD1_k127_5040783_4 Glycosyltransferase, group 2 family protein - - - 0.000000000000000000000000000000003117 140.0
HKD1_k127_5040783_5 transferase activity, transferring acyl groups - - - 0.0000000000000000000003691 108.0
HKD1_k127_5040783_6 PFAM ABC transporter related K09691 - - 0.0000000000000000000004989 103.0
HKD1_k127_5040783_7 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 0.000000000000000000001763 108.0
HKD1_k127_5040783_8 Glycosyltransferase like family 2 K16870 - 2.4.1.289 0.0000000000000000001579 102.0
HKD1_k127_5040783_9 Methionine biosynthesis protein MetW K00568 - 2.1.1.222,2.1.1.64 0.000000000000000006768 98.0
HKD1_k127_5056828_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 461.0
HKD1_k127_5056828_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 392.0
HKD1_k127_5056828_10 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000007058 180.0
HKD1_k127_5056828_11 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000001407 160.0
HKD1_k127_5056828_12 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000001199 157.0
HKD1_k127_5056828_13 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000001448 155.0
HKD1_k127_5056828_14 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000006662 139.0
HKD1_k127_5056828_15 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000005825 134.0
HKD1_k127_5056828_16 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000000000000000000001748 129.0
HKD1_k127_5056828_17 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000001318 110.0
HKD1_k127_5056828_18 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000003889 99.0
HKD1_k127_5056828_19 Could be involved in septation K06412 - - 0.000000000000000000006683 96.0
HKD1_k127_5056828_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000007026 262.0
HKD1_k127_5056828_20 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000002613 80.0
HKD1_k127_5056828_21 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000003929 85.0
HKD1_k127_5056828_22 Domain of unknown function (DUF4398) - - - 0.00002196 55.0
HKD1_k127_5056828_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000002321 225.0
HKD1_k127_5056828_4 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000001759 234.0
HKD1_k127_5056828_5 TonB-dependent receptor plug - - - 0.0000000000000000000000000000000000000000000000001114 183.0
HKD1_k127_5056828_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000001025 182.0
HKD1_k127_5056828_7 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000003105 178.0
HKD1_k127_5056828_8 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000004945 184.0
HKD1_k127_5056828_9 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000001147 169.0
HKD1_k127_5057633_0 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 320.0
HKD1_k127_5057633_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000001157 137.0
HKD1_k127_5057633_2 Hydrogenase maturation protease K08315 - 3.4.23.51 0.000000000000000000000005334 116.0
HKD1_k127_5059801_0 Tricorn protease homolog K08676 - - 0.0 1063.0
HKD1_k127_5059801_1 OsmC-like protein K04063 - - 0.000000002441 58.0
HKD1_k127_5059801_2 Methylmuconolactone methyl-isomerase - - - 0.000004306 55.0
HKD1_k127_5063247_0 amino acid K03294 - - 5.873e-196 617.0
HKD1_k127_5063247_1 tRNA pseudouridine synthase K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000001544 209.0
HKD1_k127_5063247_2 aminopeptidase activity K19689 - - 0.00000000000000000000000000000000000000000000002293 192.0
HKD1_k127_5063247_3 - - - - 0.00002196 47.0
HKD1_k127_5067634_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.182e-235 735.0
HKD1_k127_5067634_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 1.71e-220 696.0
HKD1_k127_5067634_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000001826 98.0
HKD1_k127_5067634_11 Protein of unknown function (DUF1573) - - - 0.000000000000001192 92.0
HKD1_k127_5067634_12 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000259 68.0
HKD1_k127_5067634_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.00002959 55.0
HKD1_k127_5067634_2 Elongator protein 3, MiaB family, Radical SAM K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 516.0
HKD1_k127_5067634_3 Mur ligase, middle domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 322.0
HKD1_k127_5067634_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002054 252.0
HKD1_k127_5067634_5 receptor K16092 - - 0.000000000000000000000000000000000000000000000001394 195.0
HKD1_k127_5067634_6 PFAM Stage II sporulation E family protein K01079,K07315 - 3.1.3.3 0.000000000000000000000000000000000000175 159.0
HKD1_k127_5067634_7 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000001411 133.0
HKD1_k127_5067634_8 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.00000000000000000000000006857 123.0
HKD1_k127_5067634_9 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000002957 106.0
HKD1_k127_5068985_0 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 427.0
HKD1_k127_5068985_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 373.0
HKD1_k127_5068985_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000006093 134.0
HKD1_k127_5068985_3 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000421 70.0
HKD1_k127_5081872_0 butyrate kinase activity K00625,K00929,K04020,K13788 GO:0003674,GO:0003824,GO:0006950,GO:0008150,GO:0008959,GO:0009266,GO:0009408,GO:0009628,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0050896 2.3.1.8,2.7.2.7 3.701e-291 906.0
HKD1_k127_5081872_1 Phosphate acetyl/butaryl transferase K00634,K13788 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 302.0
HKD1_k127_511056_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.664e-217 697.0
HKD1_k127_511056_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 499.0
HKD1_k127_511056_10 Fimbrial assembly protein (PilN) K02663 - - 0.00000000264 66.0
HKD1_k127_511056_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 361.0
HKD1_k127_511056_3 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 319.0
HKD1_k127_511056_4 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 324.0
HKD1_k127_511056_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008218 286.0
HKD1_k127_511056_6 ig-like, plexins, transcription factors - - - 0.00000000000000000000000001548 127.0
HKD1_k127_511056_7 Pilus assembly protein, PilO K02664 - - 0.000000000000000000002533 105.0
HKD1_k127_511056_8 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000003513 86.0
HKD1_k127_511056_9 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000008223 86.0
HKD1_k127_5113436_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 529.0
HKD1_k127_5113436_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 424.0
HKD1_k127_5113436_10 response to copper ion - - - 0.0002611 53.0
HKD1_k127_5113436_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 318.0
HKD1_k127_5113436_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 311.0
HKD1_k127_5113436_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000001185 253.0
HKD1_k127_5113436_5 Peptidase C26 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002866 242.0
HKD1_k127_5113436_6 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000001139 215.0
HKD1_k127_5113436_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000002413 159.0
HKD1_k127_5113436_8 The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis K13830 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 1.1.1.25,2.5.1.19,2.7.1.71,4.2.1.10,4.2.3.4 0.0000000000000000000000000000000003829 149.0
HKD1_k127_5113436_9 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.0000000000000000000000000001777 124.0
HKD1_k127_5125648_0 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 548.0
HKD1_k127_5125648_1 Serine dehydratase K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 507.0
HKD1_k127_5165166_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 441.0
HKD1_k127_5165166_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000003416 243.0
HKD1_k127_5182080_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 608.0
HKD1_k127_5182100_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204 1.2.4.1 0.0 1073.0
HKD1_k127_5182100_1 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 5.668e-197 619.0
HKD1_k127_5182100_10 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000001035 137.0
HKD1_k127_5182100_11 Bacterial membrane protein, YfhO - - - 0.00000000000008853 85.0
HKD1_k127_5182100_2 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 546.0
HKD1_k127_5182100_3 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 508.0
HKD1_k127_5182100_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 424.0
HKD1_k127_5182100_5 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 416.0
HKD1_k127_5182100_6 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006055 259.0
HKD1_k127_5182100_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005403 246.0
HKD1_k127_5182100_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000002312 218.0
HKD1_k127_5182100_9 acetyltransferase K18815 - 2.3.1.82 0.0000000000000000000000000000000000000000003435 163.0
HKD1_k127_5183601_0 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 542.0
HKD1_k127_5183601_1 magnesium chelatase K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 512.0
HKD1_k127_5183601_2 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 456.0
HKD1_k127_5183601_3 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 396.0
HKD1_k127_5183601_4 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 350.0
HKD1_k127_5183601_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 336.0
HKD1_k127_5183601_6 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000008674 238.0
HKD1_k127_5183601_7 PFAM Ferritin Dps family protein K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000009484 182.0
HKD1_k127_5183601_8 Phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000000007981 150.0
HKD1_k127_5183601_9 Transcription factor zinc-finger K09981 - - 0.00000000000000000000002957 106.0
HKD1_k127_5188809_0 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 562.0
HKD1_k127_5188809_1 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 309.0
HKD1_k127_5188809_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000004018 266.0
HKD1_k127_5188809_3 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003863 254.0
HKD1_k127_5188809_4 isochorismatase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000001702 232.0
HKD1_k127_5188809_5 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000003348 189.0
HKD1_k127_5188809_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000009703 86.0
HKD1_k127_5188809_7 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000002379 66.0
HKD1_k127_5192433_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 558.0
HKD1_k127_5192433_1 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007944 432.0
HKD1_k127_5248350_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 640.0
HKD1_k127_5248350_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 368.0
HKD1_k127_5248350_10 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000008374 91.0
HKD1_k127_5248350_11 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000005773 62.0
HKD1_k127_5248350_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 324.0
HKD1_k127_5248350_3 Glycosyltransferase, group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008811 290.0
HKD1_k127_5248350_4 pfam abc K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001734 261.0
HKD1_k127_5248350_5 ABC transporter, permease protein K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004233 258.0
HKD1_k127_5248350_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002922 247.0
HKD1_k127_5248350_7 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000002009 259.0
HKD1_k127_5248350_8 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000009319 129.0
HKD1_k127_5248350_9 Glycosyl transferase family 2 K07011 - - 0.000000000000000000093 98.0
HKD1_k127_5254475_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000001236 261.0
HKD1_k127_5254475_1 Ras family - - - 0.00000000000000000000000000000000000000000000000000000000003733 230.0
HKD1_k127_5254475_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000007447 198.0
HKD1_k127_5254475_3 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.00000000000000000000000000000005091 136.0
HKD1_k127_5254475_4 cheY-homologous receiver domain - - - 0.000000000000000000000000000002026 125.0
HKD1_k127_5254475_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000001003 132.0
HKD1_k127_5254475_6 general secretion pathway protein K08084,K08085 - - 0.000001945 55.0
HKD1_k127_5270494_0 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000001822 226.0
HKD1_k127_5270494_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000001955 189.0
HKD1_k127_5270494_2 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000004803 113.0
HKD1_k127_527464_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005914 374.0
HKD1_k127_527464_1 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000002313 229.0
HKD1_k127_527464_2 nickel cation binding K04651 - - 0.000000000000007354 83.0
HKD1_k127_5331348_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 447.0
HKD1_k127_5337806_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 326.0
HKD1_k127_5337806_1 Carbon dioxide concentrating mechanism carboxysome shell protein - - - 0.00000000000000000000000003558 116.0
HKD1_k127_5337806_2 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000000002008 99.0
HKD1_k127_5337806_3 Ethanolamine utilisation protein EutN/carboxysome K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000000000000001249 89.0
HKD1_k127_5345919_0 Involved in the tonB-independent uptake of proteins K01256,K03641 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 310.0
HKD1_k127_5345919_1 major pilin protein fima - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001241 259.0
HKD1_k127_5345919_2 Protein of unknown function (DUF1579) - - - 0.0000000000000000000000000000000000000000000004446 173.0
HKD1_k127_5348230_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 431.0
HKD1_k127_5348230_1 NAD dependent epimerase dehydratase family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000001426 274.0
HKD1_k127_5348230_2 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002201 261.0
HKD1_k127_5348230_3 phosphorelay signal transduction system K14987 - - 0.0000000000000000000000000000000000000000000000000000000000002867 224.0
HKD1_k127_5348230_4 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000002172 173.0
HKD1_k127_5348230_5 cheY-homologous receiver domain - - - 0.00000000000000000000002146 104.0
HKD1_k127_5348230_6 PAP2 superfamily - - - 0.000000000000000005467 95.0
HKD1_k127_5348230_7 CAAX protease self-immunity - - - 0.000000416 62.0
HKD1_k127_5348230_8 - - - - 0.00001072 57.0
HKD1_k127_5359408_0 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 420.0
HKD1_k127_5359408_1 BMC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001022 278.0
HKD1_k127_5359408_10 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000000003536 100.0
HKD1_k127_5359408_11 Bacterial membrane protein, YfhO - - - 0.0000000000000000000004057 113.0
HKD1_k127_5359408_12 Biopolymer transport protein K03559,K03560 - - 0.000000000000000000005083 98.0
HKD1_k127_5359408_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000583 278.0
HKD1_k127_5359408_3 Esterase-like activity of phytase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000003313 280.0
HKD1_k127_5359408_4 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000005003 226.0
HKD1_k127_5359408_5 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000001948 149.0
HKD1_k127_5359408_6 BMC K04027 - - 0.000000000000000000000000000000001797 132.0
HKD1_k127_5359408_7 Tetratricopeptide repeat - - - 0.000000000000000000000001059 115.0
HKD1_k127_5359408_8 TIGRFAM TonB K03832 - - 0.000000000000000000000001435 113.0
HKD1_k127_5359408_9 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000273 106.0
HKD1_k127_5374771_0 Glycosyl transferase, family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000001162 162.0
HKD1_k127_5374771_1 TIGRFAM methyltransferase FkbM - - - 0.0000000000000000000000000000000000000003541 164.0
HKD1_k127_5374771_2 pfam abc K09691 - - 0.00000000000000001333 89.0
HKD1_k127_5374771_3 Glutamate formimidoyltransferase K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000861 66.0
HKD1_k127_5420593_0 ABC transporter, (ATP-binding protein) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 317.0
HKD1_k127_5420593_1 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002445 267.0
HKD1_k127_5431291_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 579.0
HKD1_k127_5431291_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 567.0
HKD1_k127_5431291_10 class II (D K K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000001491 204.0
HKD1_k127_5431291_11 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000002284 164.0
HKD1_k127_5431291_12 ApaG domain K06195 - - 0.0000000000000000000000000000000000000338 166.0
HKD1_k127_5431291_13 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000001297 147.0
HKD1_k127_5431291_14 SMART phosphoesterase PA-phosphatase related - - - 0.00000000000000000000000001304 123.0
HKD1_k127_5431291_15 DoxX - - - 0.00000000000000000000000003252 113.0
HKD1_k127_5431291_16 PFAM Peptidase M23 - - - 0.0000000000000000008187 99.0
HKD1_k127_5431291_17 Rhodanese Homology Domain - - - 0.0000008957 58.0
HKD1_k127_5431291_19 Protease prsW family - - - 0.0006236 52.0
HKD1_k127_5431291_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 533.0
HKD1_k127_5431291_3 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 489.0
HKD1_k127_5431291_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 427.0
HKD1_k127_5431291_5 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 414.0
HKD1_k127_5431291_6 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 401.0
HKD1_k127_5431291_7 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 401.0
HKD1_k127_5431291_8 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000004127 234.0
HKD1_k127_5431291_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000001033 234.0
HKD1_k127_5474687_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 1.432e-199 627.0
HKD1_k127_5474687_1 Belongs to the succinate malate CoA ligase beta subunit family K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 459.0
HKD1_k127_5474687_10 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000000003535 182.0
HKD1_k127_5474687_11 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000004617 164.0
HKD1_k127_5474687_12 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000000000002794 147.0
HKD1_k127_5474687_13 amidohydrolase - - - 0.000000000000000000000000000000000001788 158.0
HKD1_k127_5474687_14 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.00000000000000000000000000000001265 139.0
HKD1_k127_5474687_15 FMN binding - - - 0.0000000000000000000000000002865 121.0
HKD1_k127_5474687_16 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.00000000000000000001211 106.0
HKD1_k127_5474687_18 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000004699 70.0
HKD1_k127_5474687_19 Methionine biosynthesis protein MetW - - - 0.000001348 59.0
HKD1_k127_5474687_2 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 406.0
HKD1_k127_5474687_20 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000857 59.0
HKD1_k127_5474687_3 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 362.0
HKD1_k127_5474687_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 350.0
HKD1_k127_5474687_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 327.0
HKD1_k127_5474687_6 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 335.0
HKD1_k127_5474687_7 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 330.0
HKD1_k127_5474687_8 YmdB-like protein K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002887 287.0
HKD1_k127_5474687_9 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001461 239.0
HKD1_k127_5532623_0 PA domain K14647 GO:0005575,GO:0005576 - 1.937e-195 639.0
HKD1_k127_5532623_1 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 536.0
HKD1_k127_5532623_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 316.0
HKD1_k127_5532623_3 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000003476 211.0
HKD1_k127_5532623_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000051 207.0
HKD1_k127_5532623_5 Transcriptional regulatory protein, C terminal - - - 0.00000000000000002689 97.0
HKD1_k127_5532623_6 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000004768 83.0
HKD1_k127_5532623_7 Tetratricopeptide repeat - - - 0.0002743 54.0
HKD1_k127_5549871_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 472.0
HKD1_k127_5549871_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 389.0
HKD1_k127_5549871_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01459,K01501,K11206,K13566 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0030312,GO:0044464,GO:0050152,GO:0071944,GO:0106008 3.5.1.3,3.5.1.77,3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 334.0
HKD1_k127_5549871_3 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 302.0
HKD1_k127_5549871_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 290.0
HKD1_k127_5549871_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000001074 181.0
HKD1_k127_5549871_6 phosphatidate cytidylyltransferase activity K00981 - 2.7.7.41 0.000000000000000000000000000000005943 139.0
HKD1_k127_5581358_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 4.992e-213 675.0
HKD1_k127_55938_0 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 455.0
HKD1_k127_55938_1 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000000000000000000009467 239.0
HKD1_k127_5625963_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 481.0
HKD1_k127_5625963_1 signal peptide processing K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007924 269.0
HKD1_k127_5625963_2 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000002536 179.0
HKD1_k127_5625963_3 Putative adhesin - - - 0.00000000000000000000000000000000000000000000001799 183.0
HKD1_k127_5625963_4 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000004113 109.0
HKD1_k127_5625963_5 Domain of unknown function (DUF4349) - - - 0.000002529 59.0
HKD1_k127_566464_0 Domain of unknown function (DUF1846) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 528.0
HKD1_k127_566464_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 326.0
HKD1_k127_566464_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000009045 167.0
HKD1_k127_566464_4 proline dipeptidase activity - - - 0.0001123 48.0
HKD1_k127_57_0 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 1.179e-218 702.0
HKD1_k127_57_1 B12 binding domain - - - 1.074e-203 645.0
HKD1_k127_57_10 Rubrerythrin - - - 0.0009897 48.0
HKD1_k127_57_2 prohibitin homologues K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 407.0
HKD1_k127_57_3 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 333.0
HKD1_k127_57_4 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 327.0
HKD1_k127_57_5 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001212 253.0
HKD1_k127_57_6 Dihydrodipicolinate synthetase family - - - 0.0000000000000000000000000000000000000000000000000000000000000007705 229.0
HKD1_k127_57_7 4-amino-4-deoxy-L-arabinose transferase activity K00721 - 2.4.1.83 0.0000000000000000000000000000002141 141.0
HKD1_k127_57_8 Protein of unknown function (DUF502) - - - 0.0000000000000000000007142 101.0
HKD1_k127_57_9 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.00000000000000000004814 101.0
HKD1_k127_5702859_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.581e-289 905.0
HKD1_k127_5702859_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 318.0
HKD1_k127_5702859_11 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0001393 44.0
HKD1_k127_5702859_2 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 311.0
HKD1_k127_5702859_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003811 283.0
HKD1_k127_5702859_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002911 257.0
HKD1_k127_5702859_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000005809 213.0
HKD1_k127_5702859_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000006958 192.0
HKD1_k127_5702859_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000001026 170.0
HKD1_k127_5702859_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000006629 124.0
HKD1_k127_5702859_9 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000006347 132.0
HKD1_k127_572064_0 oligopeptide transport K03305 - - 4.681e-204 650.0
HKD1_k127_572064_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 499.0
HKD1_k127_572064_2 iron-nicotianamine transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 428.0
HKD1_k127_572064_3 DinB superfamily - - - 0.0000000000003926 77.0
HKD1_k127_572064_4 - - - - 0.000000000002773 81.0
HKD1_k127_5727314_0 iron-nicotianamine transmembrane transporter activity - - - 2.873e-219 700.0
HKD1_k127_5727314_1 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 472.0
HKD1_k127_5727314_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 289.0
HKD1_k127_5727314_3 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000002691 158.0
HKD1_k127_5727314_4 Thioredoxin-like - - - 0.0000000000000000001339 96.0
HKD1_k127_5727314_5 Inter-alpha-trypsin inhibitor heavy chain - GO:0002526,GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0008150,GO:0009892,GO:0009987,GO:0010033,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016020,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034097,GO:0034774,GO:0042221,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0071944,GO:0080090,GO:0097708,GO:0098772,GO:0099503 - 0.000000009845 66.0
HKD1_k127_5727314_6 Belongs to the ompA family K03286 - - 0.0001941 51.0
HKD1_k127_591149_0 DNA photolyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004299 260.0
HKD1_k127_591149_2 lyase activity - - - 0.0000003904 61.0
HKD1_k127_591149_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000009965 56.0
HKD1_k127_5921492_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 4.499e-218 685.0
HKD1_k127_5921492_1 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 326.0
HKD1_k127_5921492_2 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000002232 170.0
HKD1_k127_5921492_3 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000007881 117.0
HKD1_k127_5936193_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 2.316e-295 925.0
HKD1_k127_5936193_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 327.0
HKD1_k127_5936193_2 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000005619 113.0
HKD1_k127_60153_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.528e-249 783.0
HKD1_k127_60153_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.08e-226 735.0
HKD1_k127_60153_10 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000005227 214.0
HKD1_k127_60153_11 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000155 180.0
HKD1_k127_60153_12 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000001656 186.0
HKD1_k127_60153_13 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000001476 168.0
HKD1_k127_60153_14 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000002274 157.0
HKD1_k127_60153_15 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000009957 130.0
HKD1_k127_60153_16 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000002507 116.0
HKD1_k127_60153_17 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000002145 111.0
HKD1_k127_60153_18 metal-sulfur cluster biosynthetic - - - 0.000000000000000000000009214 105.0
HKD1_k127_60153_19 PFAM YbbR family protein - - - 0.00000000000000000000545 105.0
HKD1_k127_60153_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 514.0
HKD1_k127_60153_20 Zn peptidase - - - 0.0000000000000000000353 103.0
HKD1_k127_60153_21 Belongs to the universal stress protein A family - - - 0.0000000000000000000829 96.0
HKD1_k127_60153_22 DSBA-like thioredoxin domain - - - 0.00000000000000002023 95.0
HKD1_k127_60153_23 peptidase inhibitor activity - - - 0.00000000000000003589 97.0
HKD1_k127_60153_24 protein kinase activity - - - 0.0000000000000002824 94.0
HKD1_k127_60153_25 GGDEF domain - - - 0.000000000001661 75.0
HKD1_k127_60153_3 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 433.0
HKD1_k127_60153_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 391.0
HKD1_k127_60153_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 344.0
HKD1_k127_60153_6 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 344.0
HKD1_k127_60153_7 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003694 282.0
HKD1_k127_60153_8 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000001156 254.0
HKD1_k127_60153_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000004522 225.0
HKD1_k127_6043473_0 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 300.0
HKD1_k127_6043473_1 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000004883 213.0
HKD1_k127_6043473_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000002999 126.0
HKD1_k127_6062681_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 557.0
HKD1_k127_6062681_1 Protein of unknown function (DUF541) K09797 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001805 288.0
HKD1_k127_6062681_2 DinB family - - - 0.00000000000000000000000000000000000000000005784 168.0
HKD1_k127_6067251_0 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 474.0
HKD1_k127_6067251_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 301.0
HKD1_k127_6067251_2 Predicted permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004045 251.0
HKD1_k127_6067251_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000112 233.0
HKD1_k127_6067251_4 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.000000000000000000000000000000000000000000000009775 186.0
HKD1_k127_6067251_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000001398 123.0
HKD1_k127_6067251_6 regulatory protein, arsR K03892 - - 0.0000000000001206 78.0
HKD1_k127_6067251_7 - - - - 0.0000000003083 68.0
HKD1_k127_6067251_8 SH3 type 3 domain protein K01447 - 3.5.1.28 0.000000000839 68.0
HKD1_k127_6069032_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 459.0
HKD1_k127_6069032_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 361.0
HKD1_k127_6069032_2 COG1606 ATP-utilizing enzymes of the PP-loop superfamily K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007048 272.0
HKD1_k127_6069032_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000002579 244.0
HKD1_k127_6069032_4 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000001058 194.0
HKD1_k127_6069032_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.000000000000000000000000000000000002799 145.0
HKD1_k127_6069032_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000002872 109.0
HKD1_k127_6075443_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.062e-294 932.0
HKD1_k127_6075443_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 495.0
HKD1_k127_6075443_10 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000004409 57.0
HKD1_k127_6075443_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 389.0
HKD1_k127_6075443_3 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001152 257.0
HKD1_k127_6075443_4 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000001213 227.0
HKD1_k127_6075443_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000006406 205.0
HKD1_k127_6075443_6 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000005932 175.0
HKD1_k127_6075443_7 cheY-homologous receiver domain - - - 0.000000000000000000000284 102.0
HKD1_k127_6075443_8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000003878 89.0
HKD1_k127_6075443_9 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000009337 94.0
HKD1_k127_6076344_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.09e-293 921.0
HKD1_k127_6076344_1 GTP-binding protein TypA K06207 - - 2.726e-258 810.0
HKD1_k127_6076344_10 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 370.0
HKD1_k127_6076344_11 abc transporter atp-binding protein K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 360.0
HKD1_k127_6076344_12 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 343.0
HKD1_k127_6076344_13 Radical SAM superfamily K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 308.0
HKD1_k127_6076344_14 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003494 286.0
HKD1_k127_6076344_15 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005653 288.0
HKD1_k127_6076344_16 PFAM Uracil DNA glycosylase superfamily K21929 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000003209 248.0
HKD1_k127_6076344_17 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000008299 207.0
HKD1_k127_6076344_18 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000005796 190.0
HKD1_k127_6076344_19 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000003283 181.0
HKD1_k127_6076344_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 2.454e-216 688.0
HKD1_k127_6076344_20 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000008218 171.0
HKD1_k127_6076344_21 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000003601 164.0
HKD1_k127_6076344_22 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000001099 151.0
HKD1_k127_6076344_23 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000001971 160.0
HKD1_k127_6076344_24 domain, Protein - - - 0.00000000000000000000000000000000005766 154.0
HKD1_k127_6076344_25 Ubiquinone biosynthesis protein UbiA K02548 - 2.5.1.74 0.0000000000000000000000000000005633 138.0
HKD1_k127_6076344_26 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000001097 126.0
HKD1_k127_6076344_27 Thioesterase K01075 - 3.1.2.23 0.0000000000000000000000001194 115.0
HKD1_k127_6076344_28 Tetratricopeptide repeat - - - 0.0000000000000000000000003117 119.0
HKD1_k127_6076344_29 PFAM Uncharacterised protein family (UPF0104) K07027 - - 0.000000000002974 79.0
HKD1_k127_6076344_3 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 539.0
HKD1_k127_6076344_30 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000003203 76.0
HKD1_k127_6076344_31 DNA polymerase III subunit chi K02339 - 2.7.7.7 0.000000002956 64.0
HKD1_k127_6076344_32 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000009379 66.0
HKD1_k127_6076344_33 Cyclic nucleotide-monophosphate binding domain - - - 0.00000009175 65.0
HKD1_k127_6076344_34 Outer membrane protein (OmpH-like) K06142 - - 0.0000003791 59.0
HKD1_k127_6076344_35 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000004792 57.0
HKD1_k127_6076344_4 ADP-glyceromanno-heptose 6-epimerase activity K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 475.0
HKD1_k127_6076344_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 464.0
HKD1_k127_6076344_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 404.0
HKD1_k127_6076344_8 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 392.0
HKD1_k127_6076344_9 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 373.0
HKD1_k127_6080371_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 482.0
HKD1_k127_6080371_1 Doxx family K15977 - - 0.00000000000000000000000000000000000000000000006773 173.0
HKD1_k127_6080371_2 L-malate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000003051 179.0
HKD1_k127_6080371_3 Transglycosylase associated protein - - - 0.0000000000000000000000000000007615 124.0
HKD1_k127_6080371_4 Cytidylyltransferase-like - - - 0.0000000000000003818 87.0
HKD1_k127_6094453_0 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000002122 215.0
HKD1_k127_6094453_1 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000774 165.0
HKD1_k127_6094453_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000001514 166.0
HKD1_k127_6094453_3 Divergent 4Fe-4S mono-cluster - - - 0.0000000000000000000398 90.0
HKD1_k127_6097559_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1180.0
HKD1_k127_6097559_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 5.175e-273 866.0
HKD1_k127_6097559_10 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003676 287.0
HKD1_k127_6097559_11 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.0000000000000000000000000000000000000000000000000000000000000000000002952 246.0
HKD1_k127_6097559_12 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003022 267.0
HKD1_k127_6097559_13 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001033 241.0
HKD1_k127_6097559_14 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000004627 217.0
HKD1_k127_6097559_15 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000001588 190.0
HKD1_k127_6097559_16 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000005556 177.0
HKD1_k127_6097559_17 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000001141 172.0
HKD1_k127_6097559_18 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000001205 180.0
HKD1_k127_6097559_19 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000004561 170.0
HKD1_k127_6097559_2 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 536.0
HKD1_k127_6097559_20 SMART Nucleotide binding protein, PINc K07175 - - 0.000000000000000000000000000000000000005751 165.0
HKD1_k127_6097559_21 Xanthine and CO dehydrogenases maturation factor XdhC CoxF family K07402 - - 0.0000000000000000000000000000003251 134.0
HKD1_k127_6097559_22 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000002513 129.0
HKD1_k127_6097559_23 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.00000000000000000000000000000492 136.0
HKD1_k127_6097559_24 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000009392 116.0
HKD1_k127_6097559_25 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000001465 89.0
HKD1_k127_6097559_26 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000008435 87.0
HKD1_k127_6097559_27 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000001014 72.0
HKD1_k127_6097559_28 Membrane - - - 0.0000001842 62.0
HKD1_k127_6097559_29 ABC transporter K02013 - 3.6.3.34 0.000001903 55.0
HKD1_k127_6097559_3 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K20447 - 1.17.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 552.0
HKD1_k127_6097559_30 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.00001529 59.0
HKD1_k127_6097559_4 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 497.0
HKD1_k127_6097559_5 phosphorelay signal transduction system K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 407.0
HKD1_k127_6097559_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 311.0
HKD1_k127_6097559_7 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 308.0
HKD1_k127_6097559_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 306.0
HKD1_k127_6097559_9 Belongs to the LTA synthase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002035 306.0
HKD1_k127_6106293_0 Tricorn protease homolog - - - 0.0 1432.0
HKD1_k127_6106293_1 Oligoendopeptidase f - - - 3.239e-226 723.0
HKD1_k127_6106293_10 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000001751 168.0
HKD1_k127_6106293_11 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000004794 169.0
HKD1_k127_6106293_12 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000004099 166.0
HKD1_k127_6106293_13 lyase activity - - - 0.0000000000000000000002438 113.0
HKD1_k127_6106293_14 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000001475 83.0
HKD1_k127_6106293_15 Helix-turn-helix domain - - - 0.000000000003171 76.0
HKD1_k127_6106293_16 4Fe-4S binding domain - - - 0.0000000006008 69.0
HKD1_k127_6106293_2 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 545.0
HKD1_k127_6106293_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 518.0
HKD1_k127_6106293_4 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 445.0
HKD1_k127_6106293_5 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 412.0
HKD1_k127_6106293_6 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 340.0
HKD1_k127_6106293_7 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 316.0
HKD1_k127_6106293_8 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001909 285.0
HKD1_k127_6106293_9 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001161 258.0
HKD1_k127_6162353_0 UvrD/REP helicase N-terminal domain - - - 0.000000000000000000000000000000000005625 155.0
HKD1_k127_6168071_0 indolepyruvate ferredoxin oxidoreductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1117.0
HKD1_k127_6168071_1 hydrogenase large subunit K14126 - 1.8.98.5 5.237e-237 739.0
HKD1_k127_6168071_10 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03388 - 1.6.5.3,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002122 294.0
HKD1_k127_6168071_11 formate dehydrogenase (NAD+) activity K00123,K05299 - 1.17.1.10,1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006576 301.0
HKD1_k127_6168071_12 Oxidoreductase NAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001568 283.0
HKD1_k127_6168071_13 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001454 281.0
HKD1_k127_6168071_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001318 278.0
HKD1_k127_6168071_15 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006676 253.0
HKD1_k127_6168071_16 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000001818 241.0
HKD1_k127_6168071_17 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000002621 235.0
HKD1_k127_6168071_18 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001496 247.0
HKD1_k127_6168071_19 Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000001265 245.0
HKD1_k127_6168071_2 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331 - 1.12.1.3,1.6.5.3 4.934e-230 729.0
HKD1_k127_6168071_20 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000007675 220.0
HKD1_k127_6168071_21 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000001052 208.0
HKD1_k127_6168071_22 spore germination - - - 0.00000000000000000000000000000000000000000000000000005662 198.0
HKD1_k127_6168071_23 Hydrogenase maturation protease K00442 - - 0.000000000000000000000000000000000000000009788 160.0
HKD1_k127_6168071_24 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000006789 141.0
HKD1_k127_6168071_25 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000000000000003076 134.0
HKD1_k127_6168071_26 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000001839 106.0
HKD1_k127_6168071_27 4Fe-4S dicluster domain - - - 0.00000000000000000003894 100.0
HKD1_k127_6168071_28 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.00000000000000007718 87.0
HKD1_k127_6168071_29 Domain of unknown function (DUF2520) - - - 0.0000000000000001472 91.0
HKD1_k127_6168071_3 Heat shock 70 kDa protein K04043 - - 1.434e-225 715.0
HKD1_k127_6168071_30 Hydrogenase maturation protease - - - 0.00000000000001304 80.0
HKD1_k127_6168071_33 - - - - 0.0000003293 58.0
HKD1_k127_6168071_4 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 474.0
HKD1_k127_6168071_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 454.0
HKD1_k127_6168071_6 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 429.0
HKD1_k127_6168071_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 381.0
HKD1_k127_6168071_8 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126,K17993 GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494 1.12.1.3,1.12.1.5,1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 359.0
HKD1_k127_6168071_9 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 298.0
HKD1_k127_61877_0 Phosphoglucose isomerase K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 8.092e-273 845.0
HKD1_k127_61877_1 - - - - 0.00000001257 60.0
HKD1_k127_6195826_0 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 465.0
HKD1_k127_6195826_1 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 420.0
HKD1_k127_6195826_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 370.0
HKD1_k127_6195826_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000003421 203.0
HKD1_k127_6195826_4 TIGRFAM PAS domain S-box - - - 0.000000000000000000000000000000000000000000000000000579 203.0
HKD1_k127_6195826_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000007337 159.0
HKD1_k127_6195826_6 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.0000000000000000001212 104.0
HKD1_k127_6211616_0 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 507.0
HKD1_k127_6211616_1 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 469.0
HKD1_k127_6211616_10 GTP cyclohydrolase 1 K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000281 189.0
HKD1_k127_6211616_11 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000008639 158.0
HKD1_k127_6211616_12 of the major facilitator superfamily K08151 - - 0.00000000000000000003572 96.0
HKD1_k127_6211616_13 overlaps another CDS with the same product name K16091 - - 0.0000000000000000009413 100.0
HKD1_k127_6211616_15 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000002064 78.0
HKD1_k127_6211616_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 435.0
HKD1_k127_6211616_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 422.0
HKD1_k127_6211616_4 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 410.0
HKD1_k127_6211616_5 curli production assembly transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 295.0
HKD1_k127_6211616_6 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008955 300.0
HKD1_k127_6211616_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000006256 238.0
HKD1_k127_6211616_8 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000002289 196.0
HKD1_k127_6211616_9 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000001476 176.0
HKD1_k127_6215402_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 366.0
HKD1_k127_6215402_1 GTP binding K06883 - - 0.000000000000000000000000000000000000000000000000000001961 195.0
HKD1_k127_6215402_2 Peptidase C26 K07010 - - 0.000000000000000000000000000000003512 137.0
HKD1_k127_6215402_3 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000001767 95.0
HKD1_k127_6216621_0 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 460.0
HKD1_k127_6216621_1 PFAM HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 363.0
HKD1_k127_6216621_10 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000001939 125.0
HKD1_k127_6216621_12 AsmA-like C-terminal region K07290 - - 0.0000000000000000000003913 112.0
HKD1_k127_6216621_13 BatB protein K07114 - - 0.000000000000006296 89.0
HKD1_k127_6216621_14 - - - - 0.0000009457 60.0
HKD1_k127_6216621_15 Oxygen tolerance - - - 0.000001111 61.0
HKD1_k127_6216621_16 Multicopper oxidase - - - 0.00007199 55.0
HKD1_k127_6216621_2 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 362.0
HKD1_k127_6216621_3 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 339.0
HKD1_k127_6216621_4 Rho termination factor, RNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 330.0
HKD1_k127_6216621_5 GAF domain - - - 0.00000000000000000000000000000000000000000000000004586 192.0
HKD1_k127_6216621_6 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000002859 163.0
HKD1_k127_6216621_7 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000001688 144.0
HKD1_k127_6216621_8 - - - - 0.000000000000000000000000003706 121.0
HKD1_k127_6216621_9 YMGG-like Gly-zipper - - - 0.000000000000000000000000006119 119.0
HKD1_k127_6232771_0 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 484.0
HKD1_k127_6232771_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 337.0
HKD1_k127_6232771_2 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000849 212.0
HKD1_k127_6232771_3 secreted acid phosphatase - - - 0.00000000000000000002663 98.0
HKD1_k127_6232771_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000002945 62.0
HKD1_k127_6238539_0 ATP-binding region, ATPase domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003109 250.0
HKD1_k127_6238539_1 - - - - 0.0000000000000006015 86.0
HKD1_k127_6263742_0 Beta-lactamase class C - - - 2.153e-264 826.0
HKD1_k127_6263742_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 461.0
HKD1_k127_6263742_2 O-methyltransferase - - - 0.00000000000000000000000000000000000757 147.0
HKD1_k127_6263742_3 Prokaryotic cytochrome b561 K00127 - - 0.00000000000000002562 95.0
HKD1_k127_6263742_4 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000008957 83.0
HKD1_k127_6332404_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 420.0
HKD1_k127_6332404_1 Glycosyl transferase family 21 K19003 - 2.4.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 368.0
HKD1_k127_6332404_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 321.0
HKD1_k127_6332404_3 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001346 286.0
HKD1_k127_6332404_4 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000004913 236.0
HKD1_k127_6332404_5 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000004325 183.0
HKD1_k127_6332404_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001264 183.0
HKD1_k127_6332404_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000001453 165.0
HKD1_k127_6332404_8 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.00000000000000000000000000000000003099 155.0
HKD1_k127_6335353_0 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 425.0
HKD1_k127_6335353_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000111 232.0
HKD1_k127_6335353_2 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000001439 191.0
HKD1_k127_6335353_3 acid phosphatase activity - - - 0.0000000000000000001131 101.0
HKD1_k127_6335353_4 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000001834 89.0
HKD1_k127_6343547_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 5.439e-206 655.0
HKD1_k127_6343547_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007528 527.0
HKD1_k127_6343547_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 493.0
HKD1_k127_6343547_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 326.0
HKD1_k127_6343547_4 Sodium:solute symporter family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007021 293.0
HKD1_k127_6343547_5 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000004053 164.0
HKD1_k127_6343547_6 transcription factor binding - - - 0.000000000000000000000000000007891 124.0
HKD1_k127_6343547_7 General transcription factor 3C polypeptide K15201 - - 0.0002769 49.0
HKD1_k127_635143_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K11529,K15893 - 1.1.1.26,2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 313.0
HKD1_k127_635143_1 flavin adenine dinucleotide binding K03699,K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000008515 240.0
HKD1_k127_635143_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000001719 159.0
HKD1_k127_6388205_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009126 452.0
HKD1_k127_6388205_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 421.0
HKD1_k127_6388205_2 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 338.0
HKD1_k127_6388205_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 325.0
HKD1_k127_6388205_4 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000001159 268.0
HKD1_k127_6388205_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000001258 229.0
HKD1_k127_6388205_6 Signal peptidase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000002496 167.0
HKD1_k127_6388205_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000004944 165.0
HKD1_k127_6388205_8 Hfq protein - - - 0.0000000000000000000000000005866 119.0
HKD1_k127_6388205_9 FMN binding - - - 0.000000000000000000000000002096 118.0
HKD1_k127_6388910_0 homoserine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 467.0
HKD1_k127_6388910_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00004561 55.0
HKD1_k127_6392420_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.679e-276 872.0
HKD1_k127_6392420_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.686e-271 856.0
HKD1_k127_6392420_10 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005406 269.0
HKD1_k127_6392420_11 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000005768 259.0
HKD1_k127_6392420_12 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000007781 227.0
HKD1_k127_6392420_13 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000006471 221.0
HKD1_k127_6392420_14 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000247 205.0
HKD1_k127_6392420_15 helix_turn_helix gluconate operon transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000006269 192.0
HKD1_k127_6392420_16 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000002644 179.0
HKD1_k127_6392420_17 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000002176 187.0
HKD1_k127_6392420_18 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000001783 151.0
HKD1_k127_6392420_19 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000009691 150.0
HKD1_k127_6392420_2 ferrous iron transmembrane transporter activity K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 597.0
HKD1_k127_6392420_20 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000626 139.0
HKD1_k127_6392420_21 Lipoate-protein ligase - - - 0.00000000000000000000000000002846 128.0
HKD1_k127_6392420_22 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000001857 113.0
HKD1_k127_6392420_23 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000003843 96.0
HKD1_k127_6392420_24 Sporulation and spore germination - - - 0.0000000000000007425 87.0
HKD1_k127_6392420_25 Polymer-forming cytoskeletal - - - 0.00000000000003336 81.0
HKD1_k127_6392420_26 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000431 72.0
HKD1_k127_6392420_27 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000001002 79.0
HKD1_k127_6392420_28 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000004234 68.0
HKD1_k127_6392420_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 463.0
HKD1_k127_6392420_4 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 416.0
HKD1_k127_6392420_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 379.0
HKD1_k127_6392420_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001517 282.0
HKD1_k127_6392420_7 Chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001311 283.0
HKD1_k127_6392420_8 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000006946 275.0
HKD1_k127_6392420_9 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000004653 268.0
HKD1_k127_6507860_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 7.947e-199 629.0
HKD1_k127_6507860_1 Glycosyltransferase like family 2 K07011,K13659 - 2.4.1.264 0.000000000000000000000000000000000000000000000000001854 207.0
HKD1_k127_6507860_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000002531 169.0
HKD1_k127_6507860_3 Glycosyl transferase family group 2 K07011 - - 0.00000000000001422 78.0
HKD1_k127_6535914_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1288.0
HKD1_k127_6535914_1 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 531.0
HKD1_k127_6535914_10 Sulfatase - - - 0.000000000000000000009912 108.0
HKD1_k127_6535914_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 531.0
HKD1_k127_6535914_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 307.0
HKD1_k127_6535914_4 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 291.0
HKD1_k127_6535914_5 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003036 296.0
HKD1_k127_6535914_6 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000009054 251.0
HKD1_k127_6535914_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000001145 229.0
HKD1_k127_6535914_8 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000000000000000000000000000000000000001758 166.0
HKD1_k127_6535914_9 DinB family - - - 0.00000000000000000000000000000000000000002414 158.0
HKD1_k127_6553341_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 4.117e-213 670.0
HKD1_k127_6553341_1 TonB-dependent receptor plug - - - 1.87e-200 655.0
HKD1_k127_6553341_10 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K03561,K12287 - - 0.0000000000000000000000000000000000000000000000000000000000000000003069 264.0
HKD1_k127_6553341_11 FCD - - - 0.00000000000000000000000000000000000000000000000000000000002435 227.0
HKD1_k127_6553341_12 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000001964 201.0
HKD1_k127_6553341_13 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000007716 212.0
HKD1_k127_6553341_14 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000002178 182.0
HKD1_k127_6553341_15 GYD domain - - - 0.000000000000000000000000000002243 126.0
HKD1_k127_6553341_17 Calcineurin-like phosphoesterase - - - 0.0000005391 61.0
HKD1_k127_6553341_2 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 591.0
HKD1_k127_6553341_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 484.0
HKD1_k127_6553341_4 Mate efflux family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 434.0
HKD1_k127_6553341_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 424.0
HKD1_k127_6553341_6 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 336.0
HKD1_k127_6553341_7 mandelate racemase muconate lactonizing K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 302.0
HKD1_k127_6553341_8 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 294.0
HKD1_k127_6553341_9 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006143 257.0
HKD1_k127_6595553_0 Carbon starvation protein K06200 - - 1.573e-215 686.0
HKD1_k127_6595553_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 514.0
HKD1_k127_6595553_2 Nacht domain - - - 0.0000000004443 72.0
HKD1_k127_66588_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 545.0
HKD1_k127_66588_1 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 524.0
HKD1_k127_66588_10 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000044 222.0
HKD1_k127_66588_11 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000008246 196.0
HKD1_k127_66588_12 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000007957 194.0
HKD1_k127_66588_13 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000000000000000000000000000000000002511 162.0
HKD1_k127_66588_14 GDP-mannose mannosyl hydrolase activity K00077,K01092,K03574 - 1.1.1.169,3.1.3.25,3.6.1.55 0.000000000000000000000000000000000001831 149.0
HKD1_k127_66588_15 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000001406 142.0
HKD1_k127_66588_16 - - - - 0.0000000000000000000000000000000004234 136.0
HKD1_k127_66588_17 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.000000000000000000000000001659 121.0
HKD1_k127_66588_18 Domain of unknown function (DUF374) - - - 0.0000000000000000000000001605 114.0
HKD1_k127_66588_19 - - - - 0.0000000000000006088 89.0
HKD1_k127_66588_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 452.0
HKD1_k127_66588_20 lysyltransferase activity K07027 - - 0.000000000563 70.0
HKD1_k127_66588_21 Resolvase - - - 0.0009521 49.0
HKD1_k127_66588_3 ABC transporter transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 424.0
HKD1_k127_66588_4 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 416.0
HKD1_k127_66588_5 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001041 288.0
HKD1_k127_66588_6 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001779 289.0
HKD1_k127_66588_7 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009875 250.0
HKD1_k127_66588_8 LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005241 254.0
HKD1_k127_66588_9 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000001987 226.0
HKD1_k127_6668635_0 AcrB/AcrD/AcrF family - - - 5.176e-259 816.0
HKD1_k127_6668635_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 6.306e-196 635.0
HKD1_k127_6668635_10 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000008701 166.0
HKD1_k127_6668635_11 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000003456 162.0
HKD1_k127_6668635_12 Putative cyclase K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000008814 149.0
HKD1_k127_6668635_13 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000000000000000007214 142.0
HKD1_k127_6668635_14 Psort location CytoplasmicMembrane, score K07088 - - 0.000000000000000000000000000004493 134.0
HKD1_k127_6668635_15 - - - - 0.0000000000000000000000003836 108.0
HKD1_k127_6668635_16 - - - - 0.00000000000000000000006478 101.0
HKD1_k127_6668635_17 - - - - 0.0000000000000000000001113 100.0
HKD1_k127_6668635_18 Transglycosylase associated protein - - - 0.000000000000000000001022 97.0
HKD1_k127_6668635_19 cheY-homologous receiver domain - - - 0.000000000004607 72.0
HKD1_k127_6668635_2 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 496.0
HKD1_k127_6668635_20 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000007684 78.0
HKD1_k127_6668635_21 Diguanylate cyclase, GGDEF domain - - - 0.0000000000371 69.0
HKD1_k127_6668635_3 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000001698 249.0
HKD1_k127_6668635_4 modulates the activities of several proteins which are inactive in their K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001477 249.0
HKD1_k127_6668635_5 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000002418 250.0
HKD1_k127_6668635_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000006254 198.0
HKD1_k127_6668635_7 PFAM DNA repair protein RadC K03630 - - 0.0000000000000000000000000000000000000000000000001101 186.0
HKD1_k127_6668635_8 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000001022 171.0
HKD1_k127_6668635_9 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000001033 169.0
HKD1_k127_6878576_0 Oligopeptidase F K08602 - - 8.405e-207 663.0
HKD1_k127_6878576_1 Peptidase family S49 K04773,K04774 - - 0.000000000000000000000000000000000000007047 156.0
HKD1_k127_6878576_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000002024 100.0
HKD1_k127_6921212_0 PFAM Prolyl oligopeptidase family - - - 1.505e-230 730.0
HKD1_k127_6921212_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 355.0
HKD1_k127_6921212_2 Protein of unknown function (DUF1232) - - - 0.00000000000000004452 85.0
HKD1_k127_694932_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1067.0
HKD1_k127_694932_1 Response regulator, receiver K01007 - 2.7.9.2 3.233e-246 793.0
HKD1_k127_694932_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 1.685e-210 663.0
HKD1_k127_694932_3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 3.205e-194 624.0
HKD1_k127_694932_4 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 558.0
HKD1_k127_694932_5 - - - - 0.00000000001659 71.0
HKD1_k127_7038610_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 334.0
HKD1_k127_7038610_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 282.0
HKD1_k127_7038610_2 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000001059 209.0
HKD1_k127_7038610_3 ATPase activity K01990,K13926 - - 0.000000000000000000000000000000000000000002935 162.0
HKD1_k127_7038610_4 - - - - 0.00000000000000000000000000000000000002225 152.0
HKD1_k127_7038610_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000005462 127.0
HKD1_k127_7052928_0 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007187 279.0
HKD1_k127_7052928_1 NmrA-like family - - - 0.000000007106 60.0
HKD1_k127_7052928_2 Redoxin K03564 - 1.11.1.15 0.0008741 42.0
HKD1_k127_7053642_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001299 266.0
HKD1_k127_7053642_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000002033 196.0
HKD1_k127_7053642_2 aldo keto reductase family K07079 - - 0.000000000000000000000000000000135 140.0
HKD1_k127_7053642_3 - - - - 0.00000000000000000724 94.0
HKD1_k127_7053642_4 Putative esterase - - - 0.0000000006465 69.0
HKD1_k127_7053642_5 - - - - 0.0002681 51.0
HKD1_k127_7056171_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 339.0
HKD1_k127_7056171_1 Glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.0000000000000000000000000000000000000002267 152.0
HKD1_k127_7097329_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K00207,K00219,K00317,K02293,K10797,K12527,K17723 - 1.3.1.1,1.3.1.2,1.3.1.31,1.3.1.34,1.3.5.5,1.5.8.1,1.5.8.2,1.97.1.9 2.866e-267 850.0
HKD1_k127_7097329_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 594.0
HKD1_k127_7097329_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 443.0
HKD1_k127_7097329_3 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 416.0
HKD1_k127_7097329_4 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 321.0
HKD1_k127_7097329_5 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 328.0
HKD1_k127_7097329_6 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000389 261.0
HKD1_k127_7097329_7 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002763 254.0
HKD1_k127_7097329_8 YhhN family - - - 0.00000000000000000000000000000008823 139.0
HKD1_k127_7097329_9 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000001591 90.0
HKD1_k127_7103658_0 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 403.0
HKD1_k127_7103658_1 TIGRFAM maf protein K06287 - - 0.000000000000000000000000000000000000000215 158.0
HKD1_k127_7103658_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000007343 141.0
HKD1_k127_7103658_3 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000008141 134.0
HKD1_k127_7103658_4 - - - - 0.000000000000000000000000002701 113.0
HKD1_k127_7103658_5 family UPF0066 K01628 - 4.1.2.17 0.000000000000000001505 93.0
HKD1_k127_7103658_6 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000002712 81.0
HKD1_k127_7103658_7 Membrane protein implicated in regulation of membrane protease activity - - - 0.0008502 50.0
HKD1_k127_7110266_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 425.0
HKD1_k127_7110266_1 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 328.0
HKD1_k127_7110266_10 - - - - 0.000001994 54.0
HKD1_k127_7110266_11 Psort location CytoplasmicMembrane, score - - - 0.000007325 57.0
HKD1_k127_7110266_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004786 260.0
HKD1_k127_7110266_3 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000001134 241.0
HKD1_k127_7110266_4 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000003283 237.0
HKD1_k127_7110266_5 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000004295 233.0
HKD1_k127_7110266_6 epimerase - - - 0.000000000000000000000000000000000000000000000000000008523 196.0
HKD1_k127_7110266_7 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000006367 194.0
HKD1_k127_7110266_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000009435 169.0
HKD1_k127_7111674_0 PHP domain protein K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009629 442.0
HKD1_k127_7111674_1 MoeA N-terminal region (domain I and II) K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 427.0
HKD1_k127_7111674_10 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005696 251.0
HKD1_k127_7111674_11 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005954 257.0
HKD1_k127_7111674_12 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000001562 228.0
HKD1_k127_7111674_13 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000000000001261 192.0
HKD1_k127_7111674_14 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000004744 188.0
HKD1_k127_7111674_15 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000004379 185.0
HKD1_k127_7111674_16 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000001246 183.0
HKD1_k127_7111674_17 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000000000001246 172.0
HKD1_k127_7111674_18 - - - - 0.00000000000000003797 91.0
HKD1_k127_7111674_19 - - - - 0.00000000003941 67.0
HKD1_k127_7111674_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 377.0
HKD1_k127_7111674_20 - - - - 0.0000000002407 64.0
HKD1_k127_7111674_21 Pilus assembly protein PilW K02656 - - 0.000001752 59.0
HKD1_k127_7111674_22 Roadblock/LC7 domain - - - 0.00002192 53.0
HKD1_k127_7111674_23 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000105 50.0
HKD1_k127_7111674_24 Belongs to the glycosyl hydrolase 3 family - - - 0.0001658 50.0
HKD1_k127_7111674_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 322.0
HKD1_k127_7111674_4 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 326.0
HKD1_k127_7111674_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000044 289.0
HKD1_k127_7111674_6 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003505 277.0
HKD1_k127_7111674_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005868 278.0
HKD1_k127_7111674_8 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000001664 261.0
HKD1_k127_7111674_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005825 259.0
HKD1_k127_7118923_0 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 293.0
HKD1_k127_7118923_1 Porin subfamily - - - 0.0000000000000000000000000000005087 140.0
HKD1_k127_7157923_0 7TM-HD extracellular K07037 - - 0.000000000000000000000000000000000000000000000000000000000001665 214.0
HKD1_k127_7157923_1 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000004204 117.0
HKD1_k127_7157923_2 Transporter associated domain K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000002576 91.0
HKD1_k127_7164109_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 601.0
HKD1_k127_7164109_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.0000000000000000000000000000000000000000000000000000000001243 209.0
HKD1_k127_7164109_2 - - - - 0.0000000000000000000000000000000000000000000000000000000007505 222.0
HKD1_k127_7164109_3 COG2217 Cation transport ATPase K17686 - 3.6.3.54 0.00000000000000000000000002467 111.0
HKD1_k127_7169033_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 511.0
HKD1_k127_7169033_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000003853 123.0
HKD1_k127_7169033_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00001143 58.0
HKD1_k127_7181541_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 597.0
HKD1_k127_7181541_1 Tricorn protease homolog K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 351.0
HKD1_k127_7181541_2 ECF sigma factor K03088 - - 0.00000000000000000000000000000000003927 142.0
HKD1_k127_7183297_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 1.005e-242 760.0
HKD1_k127_7183297_1 SMART Elongator protein 3 MiaB NifB - - - 2.827e-238 762.0
HKD1_k127_7183297_10 TIGRFAM Ammonia monooxygenase particulate methane monooxygenase, subunit A K10944 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.18.3,1.14.99.39 0.000000000000000000000000000001373 124.0
HKD1_k127_7183297_11 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000001299 115.0
HKD1_k127_7183297_12 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000003111 102.0
HKD1_k127_7183297_13 phosphinothricin N-acetyltransferase activity - - - 0.0000000000000273 85.0
HKD1_k127_7183297_14 translation initiation factor activity K12065,K13671 - - 0.0000000000002076 82.0
HKD1_k127_7183297_15 PFAM glycosyl transferase group 1 - - - 0.000000000005233 78.0
HKD1_k127_7183297_16 - - - - 0.0000000006483 72.0
HKD1_k127_7183297_17 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000007715 59.0
HKD1_k127_7183297_18 COGs COG2244 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00001864 57.0
HKD1_k127_7183297_2 methane monooxygenase, subunit C K10946 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 479.0
HKD1_k127_7183297_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 473.0
HKD1_k127_7183297_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 336.0
HKD1_k127_7183297_5 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001581 289.0
HKD1_k127_7183297_6 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001039 306.0
HKD1_k127_7183297_7 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004495 263.0
HKD1_k127_7183297_8 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004677 262.0
HKD1_k127_7183297_9 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000001522 160.0
HKD1_k127_7188217_0 Cytochrome c K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000001641 231.0
HKD1_k127_7188217_1 lipase activity K15349 - - 0.000000000000000002881 94.0
HKD1_k127_7212277_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 404.0
HKD1_k127_7212277_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 403.0
HKD1_k127_7212277_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000001184 247.0
HKD1_k127_7212277_3 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000148 73.0
HKD1_k127_7223615_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 8.041e-251 803.0
HKD1_k127_7223615_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 381.0
HKD1_k127_7223615_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000634 58.0
HKD1_k127_7223615_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000001799 55.0
HKD1_k127_7223615_12 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00008004 54.0
HKD1_k127_7223615_2 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002371 292.0
HKD1_k127_7223615_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000005264 194.0
HKD1_k127_7223615_4 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000006701 184.0
HKD1_k127_7223615_5 Sigma-70, region 4 K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000005899 173.0
HKD1_k127_7223615_6 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000003258 167.0
HKD1_k127_7223615_7 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000002539 160.0
HKD1_k127_7223615_8 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.0000000000000000000000000000000002625 155.0
HKD1_k127_7223615_9 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000002105 74.0
HKD1_k127_7246741_0 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 447.0
HKD1_k127_7246741_1 COG0616 Periplasmic serine proteases (ClpP class) K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 376.0
HKD1_k127_7246741_2 - - - - 0.000000000000000000000000000000000009976 147.0
HKD1_k127_7246741_3 Oligopeptidase F K08602 - - 0.0001071 44.0
HKD1_k127_7299791_0 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 370.0
HKD1_k127_7299791_1 Domain of unknown function (DUF1972) K12996 - - 0.00000000000000000000000000000000000000000000000000000000000000002036 233.0
HKD1_k127_7307711_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1297.0
HKD1_k127_7307711_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 500.0
HKD1_k127_7307711_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000003181 192.0
HKD1_k127_7307711_3 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000002137 75.0
HKD1_k127_7317653_0 PFAM Metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 382.0
HKD1_k127_7317653_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 347.0
HKD1_k127_7317653_2 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 334.0
HKD1_k127_7317653_3 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001729 273.0
HKD1_k127_7317653_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000125 244.0
HKD1_k127_7317653_5 Belongs to the UPF0761 family K07058 - - 0.000002368 58.0
HKD1_k127_7317653_6 Domain of unknown function (DUF4136) - - - 0.000002841 56.0
HKD1_k127_7319870_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.314e-202 648.0
HKD1_k127_7319870_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 554.0
HKD1_k127_7319870_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002965 241.0
HKD1_k127_7319870_11 PFAM Ribulose-phosphate 3-epimerase K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000003523 246.0
HKD1_k127_7319870_12 cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000004615 231.0
HKD1_k127_7319870_13 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000001003 239.0
HKD1_k127_7319870_14 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000017 223.0
HKD1_k127_7319870_15 Abc transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000001004 217.0
HKD1_k127_7319870_16 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000008401 198.0
HKD1_k127_7319870_17 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000791 196.0
HKD1_k127_7319870_18 AP endonuclease family 2 K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000884 179.0
HKD1_k127_7319870_19 positive regulation of growth rate - - - 0.000000000000000000000000000000000000000000003308 180.0
HKD1_k127_7319870_2 Aldo/keto reductase family K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 423.0
HKD1_k127_7319870_20 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000002199 182.0
HKD1_k127_7319870_21 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000008107 143.0
HKD1_k127_7319870_22 4Fe-4S binding domain - - - 0.000000000000000000000000000003923 121.0
HKD1_k127_7319870_23 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000002006 117.0
HKD1_k127_7319870_24 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000001098 116.0
HKD1_k127_7319870_25 peptidyl-tyrosine sulfation - - - 0.00000000000000000000002117 116.0
HKD1_k127_7319870_26 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.000000000000000000000421 105.0
HKD1_k127_7319870_27 phosphotransferase related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000000003093 108.0
HKD1_k127_7319870_28 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000002862 98.0
HKD1_k127_7319870_29 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000002156 77.0
HKD1_k127_7319870_3 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 435.0
HKD1_k127_7319870_30 membrane protein domain - - - 0.000000000002389 79.0
HKD1_k127_7319870_31 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116 - - 0.00000000001711 66.0
HKD1_k127_7319870_32 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000185 62.0
HKD1_k127_7319870_34 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00008002 55.0
HKD1_k127_7319870_35 PFAM response regulator receiver - - - 0.0009052 47.0
HKD1_k127_7319870_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 394.0
HKD1_k127_7319870_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 341.0
HKD1_k127_7319870_6 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 336.0
HKD1_k127_7319870_7 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 306.0
HKD1_k127_7319870_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005622 289.0
HKD1_k127_7319870_9 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003253 264.0
HKD1_k127_7339029_0 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000781 274.0
HKD1_k127_7387115_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1438.0
HKD1_k127_7387115_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 2.634e-263 823.0
HKD1_k127_7387115_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 305.0
HKD1_k127_7387115_3 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000001106 231.0
HKD1_k127_7387115_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000887 218.0
HKD1_k127_7387115_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000001007 151.0
HKD1_k127_7387115_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000004303 117.0
HKD1_k127_7387115_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000009021 76.0
HKD1_k127_7387115_8 Ribosomal protein L33 K02913 - - 0.00000000000002891 75.0
HKD1_k127_7387115_9 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000003468 55.0
HKD1_k127_7406454_0 glycosyl hydrolase, family 3 K05349 - 3.2.1.21 2.377e-298 934.0
HKD1_k127_7406454_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 8.307e-233 743.0
HKD1_k127_7406454_10 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000006335 207.0
HKD1_k127_7406454_11 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000001451 193.0
HKD1_k127_7406454_12 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000007736 190.0
HKD1_k127_7406454_13 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000001546 177.0
HKD1_k127_7406454_14 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000000000003667 127.0
HKD1_k127_7406454_15 Pfam:N_methyl_2 K02456 - - 0.0000000000000000000000000001664 127.0
HKD1_k127_7406454_16 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000236 83.0
HKD1_k127_7406454_17 general secretion pathway protein K02456,K02650 - - 0.000000000000002254 85.0
HKD1_k127_7406454_18 Pilus assembly protein K02662 - - 0.00000001079 67.0
HKD1_k127_7406454_19 PFAM Fimbrial assembly family protein K02663 - - 0.0000002301 61.0
HKD1_k127_7406454_2 PFAM Type II secretion system protein E K02652 - - 1.362e-213 677.0
HKD1_k127_7406454_20 - - - - 0.000004869 49.0
HKD1_k127_7406454_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 560.0
HKD1_k127_7406454_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 362.0
HKD1_k127_7406454_5 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 328.0
HKD1_k127_7406454_6 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 301.0
HKD1_k127_7406454_7 Belongs to the GSP D family K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000129 298.0
HKD1_k127_7406454_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001306 268.0
HKD1_k127_7406454_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000008933 231.0
HKD1_k127_7443080_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1076.0
HKD1_k127_7443080_1 amine dehydrogenase activity - - - 7.174e-245 789.0
HKD1_k127_7443080_10 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000001212 199.0
HKD1_k127_7443080_11 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000003359 199.0
HKD1_k127_7443080_12 MarR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000004622 194.0
HKD1_k127_7443080_13 DegV family - - - 0.00000000000000000000000000000000000000000000000008407 199.0
HKD1_k127_7443080_14 Ergosterol biosynthesis ERG4/ERG24 family - - - 0.00000000000000000000000000000000000000000006207 166.0
HKD1_k127_7443080_15 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000008737 159.0
HKD1_k127_7443080_16 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000009934 138.0
HKD1_k127_7443080_17 Protease prsW family - - - 0.000000000000000000000000000000199 138.0
HKD1_k127_7443080_18 - - - - 0.0000000000000000000000000000002141 128.0
HKD1_k127_7443080_19 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.000000000000000000000000001305 117.0
HKD1_k127_7443080_2 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 505.0
HKD1_k127_7443080_20 transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.000000000000000000005728 97.0
HKD1_k127_7443080_21 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000002091 104.0
HKD1_k127_7443080_22 - - - - 0.00005327 53.0
HKD1_k127_7443080_3 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 381.0
HKD1_k127_7443080_4 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 358.0
HKD1_k127_7443080_5 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009672 274.0
HKD1_k127_7443080_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003112 255.0
HKD1_k127_7443080_7 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001522 235.0
HKD1_k127_7443080_8 5-oxoprolinase (ATP-hydrolyzing) activity K07160 - - 0.000000000000000000000000000000000000000000000000000000000000004872 233.0
HKD1_k127_7443080_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000008848 216.0
HKD1_k127_74929_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000002506 252.0
HKD1_k127_74929_1 CBS domain K03699 - - 0.0000000000000000000000000000000000000002504 155.0
HKD1_k127_74929_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000543 113.0
HKD1_k127_74929_3 COG0695 Glutaredoxin and related proteins - - - 0.0001674 47.0
HKD1_k127_7559762_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 449.0
HKD1_k127_7579470_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 5.102e-201 659.0
HKD1_k127_7579470_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 434.0
HKD1_k127_7579470_10 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000009595 159.0
HKD1_k127_7579470_11 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000002005 153.0
HKD1_k127_7579470_12 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000002174 161.0
HKD1_k127_7579470_13 beta-N-acetylhexosaminidase K01207 - 3.2.1.52 0.00000000000000000000000000000001308 144.0
HKD1_k127_7579470_14 von Willebrand factor, type A - - - 0.00000000000000000000000000000009746 142.0
HKD1_k127_7579470_15 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000005334 115.0
HKD1_k127_7579470_16 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.00000000000000000008793 102.0
HKD1_k127_7579470_17 WD40-like Beta Propeller Repeat - - - 0.0000000000000003361 81.0
HKD1_k127_7579470_18 glycoprotease K14742 - - 0.0000000000003113 79.0
HKD1_k127_7579470_19 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000003812 72.0
HKD1_k127_7579470_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 396.0
HKD1_k127_7579470_20 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000844 64.0
HKD1_k127_7579470_21 Protein of unknown function (DUF1109) - - - 0.00001905 55.0
HKD1_k127_7579470_22 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0006591 45.0
HKD1_k127_7579470_23 PFAM peptidase - - - 0.0006834 52.0
HKD1_k127_7579470_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 368.0
HKD1_k127_7579470_4 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002487 280.0
HKD1_k127_7579470_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007479 279.0
HKD1_k127_7579470_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000004291 254.0
HKD1_k127_7579470_7 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000002475 231.0
HKD1_k127_7579470_8 Chaperone of endosialidase - - - 0.000000000000000000000000000000000000000000000009545 194.0
HKD1_k127_7579470_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000527 160.0
HKD1_k127_7643903_0 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 454.0
HKD1_k127_7643903_1 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 425.0
HKD1_k127_7643903_10 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000004571 189.0
HKD1_k127_7643903_11 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000001968 170.0
HKD1_k127_7643903_12 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000004039 110.0
HKD1_k127_7643903_13 Glycine cleavage H-protein - - - 0.000000000000000000019 100.0
HKD1_k127_7643903_14 zinc metalloprotease whose natural substrate is K06974 - - 0.0000000000000000000614 96.0
HKD1_k127_7643903_2 Citrate lyase, alpha subunit (CitF) K01643 - 2.8.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 402.0
HKD1_k127_7643903_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K01008,K04487 - 2.7.9.3,2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 387.0
HKD1_k127_7643903_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 374.0
HKD1_k127_7643903_5 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 331.0
HKD1_k127_7643903_6 Transferase K02527 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003197 289.0
HKD1_k127_7643903_7 4 iron, 4 sulfur cluster binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005196 247.0
HKD1_k127_7643903_8 Serine threonine protein kinase K07282,K12132,K15539 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000003387 235.0
HKD1_k127_7643903_9 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000648 216.0
HKD1_k127_7651500_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 565.0
HKD1_k127_7651500_1 phosphate transport system permease protein K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 488.0
HKD1_k127_7651500_10 Pfam Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 358.0
HKD1_k127_7651500_11 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 346.0
HKD1_k127_7651500_12 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 336.0
HKD1_k127_7651500_13 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 351.0
HKD1_k127_7651500_14 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 334.0
HKD1_k127_7651500_15 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006845 318.0
HKD1_k127_7651500_16 Penicillin-binding Protein dimerisation domain K03587,K08384,K08724,K12552,K12556 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 327.0
HKD1_k127_7651500_17 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 319.0
HKD1_k127_7651500_18 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 300.0
HKD1_k127_7651500_19 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 295.0
HKD1_k127_7651500_2 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 458.0
HKD1_k127_7651500_20 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002735 281.0
HKD1_k127_7651500_21 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007443 281.0
HKD1_k127_7651500_22 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001073 253.0
HKD1_k127_7651500_23 Ribosomal protein S1 K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007427 266.0
HKD1_k127_7651500_24 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000001645 269.0
HKD1_k127_7651500_25 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000009981 232.0
HKD1_k127_7651500_26 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000006558 224.0
HKD1_k127_7651500_27 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000001576 213.0
HKD1_k127_7651500_28 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 0.000000000000000000000000000000000000000000000000000003539 216.0
HKD1_k127_7651500_29 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.000000000000000000000000000000000000000000000000002661 207.0
HKD1_k127_7651500_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 439.0
HKD1_k127_7651500_30 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000001462 192.0
HKD1_k127_7651500_31 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000003034 181.0
HKD1_k127_7651500_32 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000006736 177.0
HKD1_k127_7651500_33 protein kinase activity - - - 0.00000000000000000000000000000000000259 158.0
HKD1_k127_7651500_35 Belongs to the MraZ family K03925 - - 0.000000000000000000000000004256 118.0
HKD1_k127_7651500_36 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000002453 110.0
HKD1_k127_7651500_38 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.00000000000000003002 96.0
HKD1_k127_7651500_39 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000008417 78.0
HKD1_k127_7651500_4 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 436.0
HKD1_k127_7651500_40 - - - - 0.000000002263 64.0
HKD1_k127_7651500_41 Essential cell division protein K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.00000007413 63.0
HKD1_k127_7651500_43 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000005014 58.0
HKD1_k127_7651500_5 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 429.0
HKD1_k127_7651500_6 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 423.0
HKD1_k127_7651500_7 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 413.0
HKD1_k127_7651500_8 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 395.0
HKD1_k127_7651500_9 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 386.0
HKD1_k127_7685450_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.836e-289 908.0
HKD1_k127_7685450_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.453e-225 709.0
HKD1_k127_7685450_10 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000001803 223.0
HKD1_k127_7685450_11 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000003291 209.0
HKD1_k127_7685450_12 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000008959 207.0
HKD1_k127_7685450_13 response regulator K07714 - - 0.0000000000000000000000000000000000000000000000001377 192.0
HKD1_k127_7685450_14 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000107 169.0
HKD1_k127_7685450_15 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000241 170.0
HKD1_k127_7685450_16 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000001381 165.0
HKD1_k127_7685450_17 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000006884 159.0
HKD1_k127_7685450_18 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000002716 149.0
HKD1_k127_7685450_19 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000002417 151.0
HKD1_k127_7685450_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.281e-196 621.0
HKD1_k127_7685450_20 Ferrous iron transport protein B K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000009105 151.0
HKD1_k127_7685450_21 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000002356 127.0
HKD1_k127_7685450_22 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000001728 106.0
HKD1_k127_7685450_23 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000006385 96.0
HKD1_k127_7685450_24 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000009491 95.0
HKD1_k127_7685450_25 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000006832 88.0
HKD1_k127_7685450_26 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.000000002268 71.0
HKD1_k127_7685450_27 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000453 57.0
HKD1_k127_7685450_28 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0002173 53.0
HKD1_k127_7685450_29 receptor K02014,K16089,K19611 - - 0.0003116 44.0
HKD1_k127_7685450_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 550.0
HKD1_k127_7685450_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 447.0
HKD1_k127_7685450_5 COG0226 ABC-type phosphate transport system periplasmic K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 435.0
HKD1_k127_7685450_6 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 365.0
HKD1_k127_7685450_7 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 365.0
HKD1_k127_7685450_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007706 289.0
HKD1_k127_7685450_9 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001198 237.0
HKD1_k127_7709205_0 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000001817 225.0
HKD1_k127_7770435_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.498e-268 842.0
HKD1_k127_7770435_1 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005075 282.0
HKD1_k127_7998928_0 Aromatic amino acid lyase K01745 - 4.3.1.3 2.295e-230 723.0
HKD1_k127_7998928_2 L-fucose isomerase activity - - - 0.00000000000000008013 89.0
HKD1_k127_819623_0 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 543.0
HKD1_k127_819623_1 alanine dehydrogenase K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 332.0
HKD1_k127_819623_2 butyrate kinase activity K00625,K00929,K04020,K13788 GO:0003674,GO:0003824,GO:0006950,GO:0008150,GO:0008959,GO:0009266,GO:0009408,GO:0009628,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0050896 2.3.1.8,2.7.2.7 0.000000000000000000000000000008235 122.0
HKD1_k127_819623_3 Rubrerythrin - - - 0.000002066 54.0
HKD1_k127_825958_0 Heat shock 70 kDa protein K04043 - - 6.175e-289 899.0
HKD1_k127_825958_1 symporter activity K03307,K11928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 512.0
HKD1_k127_825958_10 cell redox homeostasis K02199,K03671 - - 0.0000000000000000000000000000000946 132.0
HKD1_k127_825958_11 helix_turn_helix, mercury resistance K13640 - - 0.0000000000000000000000000000003531 131.0
HKD1_k127_825958_12 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000005604 124.0
HKD1_k127_825958_13 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.00000000000000000000116 103.0
HKD1_k127_825958_14 COG3209 Rhs family protein - - - 0.000000000000000001158 101.0
HKD1_k127_825958_15 - - - - 0.000000000000000005508 91.0
HKD1_k127_825958_16 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000000000007458 95.0
HKD1_k127_825958_17 Tetratricopeptide repeat - - - 0.00000000000007826 85.0
HKD1_k127_825958_18 Hsp20/alpha crystallin family K13993 - - 0.000000000000749 76.0
HKD1_k127_825958_19 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000008491 72.0
HKD1_k127_825958_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 411.0
HKD1_k127_825958_20 Domain of unknown function (DUF1844) - - - 0.000005234 54.0
HKD1_k127_825958_3 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 405.0
HKD1_k127_825958_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001773 258.0
HKD1_k127_825958_5 TIGRFAM MazG family protein K02428,K02499,K04765 - 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000178 259.0
HKD1_k127_825958_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000009013 244.0
HKD1_k127_825958_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000003027 227.0
HKD1_k127_825958_8 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000001984 195.0
HKD1_k127_825958_9 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000009861 182.0
HKD1_k127_87228_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 380.0
HKD1_k127_87228_1 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001556 244.0
HKD1_k127_87228_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000004012 224.0
HKD1_k127_87228_3 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000346 158.0
HKD1_k127_87228_4 DNA mismatch repair protein MutT - - - 0.000000000000000000000000000000109 134.0
HKD1_k127_87228_5 PFAM Tetratricopeptide repeat - - - 0.00005112 56.0
HKD1_k127_92504_0 Belongs to the glycosyl hydrolase 2 family K15855 - 3.2.1.165 8.199e-236 744.0
HKD1_k127_92504_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 547.0
HKD1_k127_92504_2 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 289.0
HKD1_k127_92504_3 Acid phosphatase - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000001447 81.0
HKD1_k127_9462_0 von Willebrand factor, type A K07114 - - 5.881e-267 841.0
HKD1_k127_9462_1 GMC oxidoreductase K03333 - 1.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 603.0
HKD1_k127_9462_2 belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 499.0
HKD1_k127_9462_3 PFAM membrane protein of K08972 - - 0.0000000000000000000000007386 108.0
HKD1_k127_9462_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000005027 108.0