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Overview

ID MAG01710
Name HKD1_bin.22
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Methylomirabilota
Class Methylomirabilia
Order Rokubacteriales
Family CSP1-6
Genus
Species
Assembly information
Completeness (%) 99.46
Contamination (%) 7.08
GC content (%) 71.0
N50 (bp) 23,670
Genome size (bp) 5,290,351

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4744

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_100936_0 Protein of unknown function (DUF3604) - - - 0.0 1020.0
HKD1_k127_100936_1 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 402.0
HKD1_k127_100936_2 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 372.0
HKD1_k127_100936_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 300.0
HKD1_k127_100936_4 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000002885 236.0
HKD1_k127_100936_5 - - - - 0.00000000000000000000000000000000000000000000000000000000002957 235.0
HKD1_k127_100936_6 HupE / UreJ protein - - - 0.00000000000000000000000000000000001604 151.0
HKD1_k127_1012298_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1285.0
HKD1_k127_1012298_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1056.0
HKD1_k127_1012298_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 405.0
HKD1_k127_1012298_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 389.0
HKD1_k127_1012298_12 Belongs to the SIS family. GutQ KpsF subfamily K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 379.0
HKD1_k127_1012298_13 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 351.0
HKD1_k127_1012298_14 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 331.0
HKD1_k127_1012298_15 P-loop ATPase protein family K06958 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 315.0
HKD1_k127_1012298_16 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005814 285.0
HKD1_k127_1012298_17 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000069 256.0
HKD1_k127_1012298_18 Permease, YjgP YjgQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002772 271.0
HKD1_k127_1012298_19 PFAM Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000001051 209.0
HKD1_k127_1012298_2 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0 1055.0
HKD1_k127_1012298_20 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000001053 192.0
HKD1_k127_1012298_21 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000008393 188.0
HKD1_k127_1012298_22 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000001241 166.0
HKD1_k127_1012298_23 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000009963 163.0
HKD1_k127_1012298_24 Polymer-forming cytoskeletal - - - 0.00000000000000000000000006087 113.0
HKD1_k127_1012298_25 NUDIX domain - - - 0.000000000000000000000002317 110.0
HKD1_k127_1012298_26 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000001505 104.0
HKD1_k127_1012298_27 TIGRFAM lipopolysaccharide transport periplasmic protein LptA K09774 - - 0.000000000000000004989 97.0
HKD1_k127_1012298_28 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000002904 60.0
HKD1_k127_1012298_29 Pfam Sulfatase K01130 - 3.1.6.1 0.0005507 48.0
HKD1_k127_1012298_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.385e-218 701.0
HKD1_k127_1012298_4 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.09e-208 661.0
HKD1_k127_1012298_5 adenosylhomocysteinase activity K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 601.0
HKD1_k127_1012298_6 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 567.0
HKD1_k127_1012298_7 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 516.0
HKD1_k127_1012298_8 COG1062 Zn-dependent alcohol dehydrogenases, class III K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 451.0
HKD1_k127_1012298_9 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 412.0
HKD1_k127_1013240_0 Molydopterin dinucleotide binding domain K00183 - - 0.00000000000000001226 83.0
HKD1_k127_1013240_1 Calcineurin-like phosphoesterase - - - 0.0000000000000009258 89.0
HKD1_k127_1060708_0 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 453.0
HKD1_k127_1060708_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 419.0
HKD1_k127_1060708_2 ADP-glyceromanno-heptose 6-epimerase activity K00311 - 1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005288 293.0
HKD1_k127_1060708_3 PFAM TspO MBR family K05770 - - 0.00000000000000000000000000000000000000000001627 168.0
HKD1_k127_1060708_4 - K21495 - - 0.000000006912 59.0
HKD1_k127_1069079_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 1.046e-298 934.0
HKD1_k127_1069079_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 572.0
HKD1_k127_1069079_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000003731 145.0
HKD1_k127_1069079_11 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000005685 135.0
HKD1_k127_1069079_12 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000001794 113.0
HKD1_k127_1069079_13 SMART helix-turn-helix domain protein K15539 - - 0.000000000000000000000292 107.0
HKD1_k127_1069079_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 543.0
HKD1_k127_1069079_3 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 553.0
HKD1_k127_1069079_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 400.0
HKD1_k127_1069079_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 373.0
HKD1_k127_1069079_6 Riboflavin biosynthesis protein RibD K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 363.0
HKD1_k127_1069079_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000006956 212.0
HKD1_k127_1069079_8 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000001191 164.0
HKD1_k127_1069079_9 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000007284 164.0
HKD1_k127_1069201_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1531.0
HKD1_k127_1069201_1 Belongs to the agmatine deiminase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 437.0
HKD1_k127_1069201_2 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 430.0
HKD1_k127_1069201_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 396.0
HKD1_k127_1069201_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008688 318.0
HKD1_k127_1069201_5 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.000000000000000000000000000000000000000000000000000000000003337 220.0
HKD1_k127_1069201_6 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000000000000000000000000000000000000004288 230.0
HKD1_k127_1069201_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000004307 124.0
HKD1_k127_1069201_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000009167 95.0
HKD1_k127_1069201_9 toxin-antitoxin pair type II binding - - - 0.0000001453 53.0
HKD1_k127_1103606_0 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 503.0
HKD1_k127_1103606_1 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 373.0
HKD1_k127_1103606_2 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 306.0
HKD1_k127_1118457_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 476.0
HKD1_k127_1118457_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 379.0
HKD1_k127_1118457_2 PFAM Extracellular ligand-binding receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 349.0
HKD1_k127_1118457_3 PFAM Extracellular ligand-binding receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 337.0
HKD1_k127_1118457_4 amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005948 289.0
HKD1_k127_1118457_5 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006211 251.0
HKD1_k127_1118457_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000642 232.0
HKD1_k127_1118457_7 iron-sulfur cluster assembly - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.00000000000000000000000003932 108.0
HKD1_k127_1118457_8 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000008441 116.0
HKD1_k127_1118457_9 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.00000000000000000005683 93.0
HKD1_k127_1150316_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 467.0
HKD1_k127_1150316_1 Polysaccharide pyruvyl transferase K19431 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007856 269.0
HKD1_k127_1150316_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000003423 158.0
HKD1_k127_1150316_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000006705 118.0
HKD1_k127_1150316_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.00000000000000000002733 100.0
HKD1_k127_1150316_5 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000002101 83.0
HKD1_k127_1150316_6 Psort location CytoplasmicMembrane, score - - - 0.0003381 48.0
HKD1_k127_118647_0 Trypsin-like serine protease K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 298.0
HKD1_k127_118647_1 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000008083 112.0
HKD1_k127_1208358_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 522.0
HKD1_k127_1208358_1 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 364.0
HKD1_k127_1208358_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 349.0
HKD1_k127_1208358_3 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 331.0
HKD1_k127_1208358_4 Bacterial type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 329.0
HKD1_k127_1208358_5 Ndr family K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000003689 241.0
HKD1_k127_1208358_6 ABC transporter, ATP-binding protein K11963 - - 0.00000000000000000000000000000000000000000000544 175.0
HKD1_k127_1208358_7 Type II secretion system (T2SS), protein M subtype b - - - 0.0000000447 63.0
HKD1_k127_1208358_8 Pfam:T4SC K02463 - - 0.00004399 53.0
HKD1_k127_1214506_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1263.0
HKD1_k127_1214506_1 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008922 477.0
HKD1_k127_1214506_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001433 279.0
HKD1_k127_1214506_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004703 278.0
HKD1_k127_1214506_4 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000004432 228.0
HKD1_k127_1214506_5 DinB superfamily - - - 0.0000000000000000000000000000000000001024 150.0
HKD1_k127_1214506_6 - - - - 0.0000000000000000000000000273 124.0
HKD1_k127_1214506_7 AMP-binding enzyme K00666 - - 0.0000000000000000000000003022 112.0
HKD1_k127_121568_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1340.0
HKD1_k127_121568_1 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 410.0
HKD1_k127_121568_10 DsrE/DsrF-like family - - - 0.000000009478 66.0
HKD1_k127_121568_11 DsrE/DsrF-like family - - - 0.000003599 53.0
HKD1_k127_121568_12 DsrE/DsrF/DrsH-like family - - - 0.000008527 55.0
HKD1_k127_121568_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 333.0
HKD1_k127_121568_3 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000485 226.0
HKD1_k127_121568_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000001001 200.0
HKD1_k127_121568_5 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000001221 196.0
HKD1_k127_121568_6 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000274 159.0
HKD1_k127_121568_7 transcriptional regulator - GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000002405 132.0
HKD1_k127_121568_8 phosphorelay signal transduction system - - - 0.00000000000000000000000001471 126.0
HKD1_k127_121568_9 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000009884 70.0
HKD1_k127_1239448_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.929e-201 645.0
HKD1_k127_1242210_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.101e-218 686.0
HKD1_k127_1242210_1 PFAM Phenylalanine and histidine ammonia-lyase K01745,K10775 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009698,GO:0009699,GO:0009800,GO:0009803,GO:0009987,GO:0016043,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019748,GO:0019752,GO:0022607,GO:0032787,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044550,GO:0045548,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 4.3.1.24,4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 515.0
HKD1_k127_1242210_10 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001508 248.0
HKD1_k127_1242210_11 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000007695 245.0
HKD1_k127_1242210_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006574 231.0
HKD1_k127_1242210_13 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000003262 199.0
HKD1_k127_1242210_14 protein conserved in bacteria - - - 0.000000000000000000000000000000000002474 151.0
HKD1_k127_1242210_15 Protein of unknown function (DUF1622) - - - 0.00000000000000000000001333 105.0
HKD1_k127_1242210_16 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - - 0.000000000000000000002608 107.0
HKD1_k127_1242210_17 Glutamine synthetase N-terminal domain K01915 - 6.3.1.2 0.000000002118 61.0
HKD1_k127_1242210_18 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000000004514 57.0
HKD1_k127_1242210_19 - - - - 0.00002112 55.0
HKD1_k127_1242210_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 458.0
HKD1_k127_1242210_3 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009776 447.0
HKD1_k127_1242210_4 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 411.0
HKD1_k127_1242210_5 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 392.0
HKD1_k127_1242210_6 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 365.0
HKD1_k127_1242210_7 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 352.0
HKD1_k127_1242210_8 L-phenylalanine transmembrane transporter activity K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 305.0
HKD1_k127_1242210_9 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 291.0
HKD1_k127_1253984_0 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004796 230.0
HKD1_k127_1253984_1 Polysaccharide biosynthesis protein - - - 0.0000001054 64.0
HKD1_k127_1267806_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000003383 196.0
HKD1_k127_1267806_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000001661 123.0
HKD1_k127_1267806_2 AMP-binding enzyme K00666 - - 0.0000000000000000000000001386 114.0
HKD1_k127_1292426_0 MacB-like periplasmic core domain K02004 - - 7.842e-237 769.0
HKD1_k127_1292426_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 548.0
HKD1_k127_1292426_10 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001583 285.0
HKD1_k127_1292426_11 nuclear chromosome segregation K01727 - 4.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002253 289.0
HKD1_k127_1292426_12 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002381 277.0
HKD1_k127_1292426_13 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007462 273.0
HKD1_k127_1292426_14 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000005692 198.0
HKD1_k127_1292426_15 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000002231 149.0
HKD1_k127_1292426_16 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000266 142.0
HKD1_k127_1292426_17 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000002584 128.0
HKD1_k127_1292426_18 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000001516 123.0
HKD1_k127_1292426_19 Evidence 4 Homologs of previously reported genes of K07145,K21481 - 1.14.99.48,1.14.99.57 0.000000000000000000000001015 119.0
HKD1_k127_1292426_2 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 543.0
HKD1_k127_1292426_20 PspC domain - - - 0.0000000000000000002113 89.0
HKD1_k127_1292426_21 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000009558 87.0
HKD1_k127_1292426_22 Memo-like protein K06990 - - 0.000000000000000136 81.0
HKD1_k127_1292426_23 Tpr repeat-containing protein - - - 0.00000000008205 72.0
HKD1_k127_1292426_24 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00001542 50.0
HKD1_k127_1292426_3 alpha/beta hydrolase fold K01563,K22318 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 442.0
HKD1_k127_1292426_4 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 440.0
HKD1_k127_1292426_5 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 327.0
HKD1_k127_1292426_6 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 322.0
HKD1_k127_1292426_7 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 314.0
HKD1_k127_1292426_8 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 290.0
HKD1_k127_1292426_9 Rhodanese Homology Domain K01011,K01613 - 2.8.1.1,2.8.1.2,4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 291.0
HKD1_k127_1324679_0 N-methylhydantoinase A acetone carboxylase, beta subunit - - - 2.516e-238 756.0
HKD1_k127_1324679_1 Protein of unknown function (DUF917) K09703 - - 2.536e-199 624.0
HKD1_k127_1324679_10 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - GO:0000166,GO:0000959,GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003723,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006970,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009414,GO:0009415,GO:0009451,GO:0009628,GO:0009631,GO:0009651,GO:0009791,GO:0009845,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031554,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034336,GO:0034641,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043242,GO:0043244,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0060567,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090351,GO:0097159,GO:0097367,GO:1900864,GO:1901265,GO:1901360,GO:1901363,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000001838 102.0
HKD1_k127_1324679_11 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000228 100.0
HKD1_k127_1324679_12 Belongs to the ompA family - - - 0.00000000000008501 83.0
HKD1_k127_1324679_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 544.0
HKD1_k127_1324679_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 476.0
HKD1_k127_1324679_4 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 437.0
HKD1_k127_1324679_5 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 409.0
HKD1_k127_1324679_6 COG1176 ABC-type spermidine putrescine transport system permease component I K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 388.0
HKD1_k127_1324679_7 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 316.0
HKD1_k127_1324679_8 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000004621 226.0
HKD1_k127_1324679_9 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000002978 125.0
HKD1_k127_1340561_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 5.495e-221 710.0
HKD1_k127_1340561_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 3.652e-198 623.0
HKD1_k127_1340561_10 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000696 141.0
HKD1_k127_1340561_11 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000006605 102.0
HKD1_k127_1340561_12 carbamoyl transferase, NodU family K00612,K16035 - - 0.00000000000000000004952 98.0
HKD1_k127_1340561_13 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000001282 91.0
HKD1_k127_1340561_14 Putative regulatory protein - - - 0.00002533 48.0
HKD1_k127_1340561_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 513.0
HKD1_k127_1340561_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 503.0
HKD1_k127_1340561_4 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 415.0
HKD1_k127_1340561_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 358.0
HKD1_k127_1340561_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009409 286.0
HKD1_k127_1340561_7 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000005687 238.0
HKD1_k127_1340561_8 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000004938 159.0
HKD1_k127_1340561_9 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000204 173.0
HKD1_k127_1375460_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1248.0
HKD1_k127_1375460_1 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 597.0
HKD1_k127_1375460_2 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 560.0
HKD1_k127_1375460_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 397.0
HKD1_k127_1375460_4 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 370.0
HKD1_k127_1375460_5 PFAM SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000007653 210.0
HKD1_k127_1375460_6 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.000000000000000000001752 99.0
HKD1_k127_1375460_7 Uncharacterized protein family, UPF0114 - - - 0.000000008289 62.0
HKD1_k127_1375460_8 PFAM Uncharacterised protein family UPF0114 - - - 0.0001379 53.0
HKD1_k127_141414_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000206 144.0
HKD1_k127_1415009_0 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 4.6e-210 663.0
HKD1_k127_1415009_1 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007913 280.0
HKD1_k127_1415009_2 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000007698 182.0
HKD1_k127_1415009_3 S4 RNA-binding domain K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000002533 181.0
HKD1_k127_147427_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 524.0
HKD1_k127_147427_1 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 341.0
HKD1_k127_147427_10 Zinc-uptake complex component A periplasmic K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000642 238.0
HKD1_k127_147427_11 PFAM periplasmic solute binding protein K09815 - - 0.000000000000000000000000000000000000000000000000000000000000001574 239.0
HKD1_k127_147427_12 ABC-type Mn2 Zn2 transport K09816 - - 0.000000000000000000000000000000000000000000000000000000000000003195 226.0
HKD1_k127_147427_13 Short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000001591 192.0
HKD1_k127_147427_14 iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000009015 189.0
HKD1_k127_147427_15 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000001177 171.0
HKD1_k127_147427_16 nuclease activity - - - 0.0000000000000000000000000000004487 128.0
HKD1_k127_147427_17 phosphate-selective porin O and P - - - 0.00000000000000000000001402 117.0
HKD1_k127_147427_18 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000008595 78.0
HKD1_k127_147427_19 Uncharacterized ACR, COG1430 K09005 - - 0.0000000007153 71.0
HKD1_k127_147427_2 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 336.0
HKD1_k127_147427_3 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003027 284.0
HKD1_k127_147427_4 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002738 296.0
HKD1_k127_147427_5 Amidohydrolase family K01464,K01466 - 3.5.2.2,3.5.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001984 298.0
HKD1_k127_147427_6 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001164 277.0
HKD1_k127_147427_7 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002102 273.0
HKD1_k127_147427_8 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001798 272.0
HKD1_k127_147427_9 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003002 262.0
HKD1_k127_1566198_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 619.0
HKD1_k127_1566198_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 623.0
HKD1_k127_1566198_10 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005948 274.0
HKD1_k127_1566198_11 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000005194 190.0
HKD1_k127_1566198_12 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000003415 160.0
HKD1_k127_1566198_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000002825 104.0
HKD1_k127_1566198_14 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000005482 100.0
HKD1_k127_1566198_15 Preprotein translocase SecG subunit K03075 - - 0.0000000000000007296 88.0
HKD1_k127_1566198_16 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 - 0.00000004452 56.0
HKD1_k127_1566198_2 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 596.0
HKD1_k127_1566198_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 473.0
HKD1_k127_1566198_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 475.0
HKD1_k127_1566198_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 414.0
HKD1_k127_1566198_6 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 411.0
HKD1_k127_1566198_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 371.0
HKD1_k127_1566198_8 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 384.0
HKD1_k127_1566198_9 transport system periplasmic component K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 308.0
HKD1_k127_164299_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 6.568e-288 897.0
HKD1_k127_164299_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 520.0
HKD1_k127_164299_10 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000002794 224.0
HKD1_k127_164299_11 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000001097 231.0
HKD1_k127_164299_12 Abc transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000002022 234.0
HKD1_k127_164299_13 Glycosyltransferase like family 2 K07011,K20444 - - 0.00000000000000000000000000000000000000000000000000000000005552 220.0
HKD1_k127_164299_14 Pterin binding enzyme K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000002535 218.0
HKD1_k127_164299_15 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000008214 194.0
HKD1_k127_164299_16 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000002553 194.0
HKD1_k127_164299_17 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000001563 197.0
HKD1_k127_164299_18 glycosyl transferase - - - 0.0000000000000000000000000000000000000000002504 173.0
HKD1_k127_164299_19 cyclopropane-fatty-acyl-phospholipid synthase - - - 0.0000000000000000000000000000000000000000003033 169.0
HKD1_k127_164299_2 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 506.0
HKD1_k127_164299_20 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.00000000000000000000000000000001369 142.0
HKD1_k127_164299_22 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000001144 130.0
HKD1_k127_164299_23 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00226,K00254 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.3.5.2,1.3.98.1 0.000000000000000000000000003351 125.0
HKD1_k127_164299_24 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog)) K04762,K06179,K06180 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.23,5.4.99.24 0.000000000000000000000000007144 125.0
HKD1_k127_164299_25 Glycosyl transferases group 1 - - - 0.0000000000000000000000005915 119.0
HKD1_k127_164299_26 DoxX K15977 - - 0.0000000000000000000001116 102.0
HKD1_k127_164299_27 PFAM Uncharacterised protein family UPF0150 - - - 0.000000001225 62.0
HKD1_k127_164299_28 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000001327 64.0
HKD1_k127_164299_29 peptidoglycan binding K02453,K03749 GO:0000910,GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0022402,GO:0030428,GO:0032153,GO:0032506,GO:0042834,GO:0044464,GO:0051301,GO:0097367 - 0.0001625 53.0
HKD1_k127_164299_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 447.0
HKD1_k127_164299_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 422.0
HKD1_k127_164299_5 TonB-dependent Receptor Plug K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 322.0
HKD1_k127_164299_6 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004447 276.0
HKD1_k127_164299_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003934 278.0
HKD1_k127_164299_8 Glycosyl transferase, family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001237 256.0
HKD1_k127_164299_9 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000586 242.0
HKD1_k127_1645629_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1182.0
HKD1_k127_1645629_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 6.567e-273 863.0
HKD1_k127_1645629_10 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000007125 236.0
HKD1_k127_1645629_11 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000002715 238.0
HKD1_k127_1645629_12 Abc transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000008089 215.0
HKD1_k127_1645629_13 2Fe-2S -binding domain protein K03518,K07302,K19819 - 1.2.5.3,1.3.99.16,1.5.99.4 0.000000000000000000000000000000000000000000000000000000000009131 214.0
HKD1_k127_1645629_14 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000002199 211.0
HKD1_k127_1645629_15 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000003165 212.0
HKD1_k127_1645629_16 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000067 192.0
HKD1_k127_1645629_17 domain, Protein - - - 0.00000000000000000000000000000000000000000000001559 193.0
HKD1_k127_1645629_18 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000001289 170.0
HKD1_k127_1645629_19 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.000000000000000000000000000000000000000000001492 186.0
HKD1_k127_1645629_2 Hydantoinaseoxoprolinase domain protein K01469,K01473 - 3.5.2.14,3.5.2.9 4.122e-241 770.0
HKD1_k127_1645629_20 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000007455 186.0
HKD1_k127_1645629_21 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000001922 177.0
HKD1_k127_1645629_22 phosphorelay signal transduction system K11443 - - 0.0000000000000000000000000000007533 140.0
HKD1_k127_1645629_23 Cupin domain - - - 0.000000000000000000000000000001273 129.0
HKD1_k127_1645629_24 Periplasmic binding protein K01999 - - 0.0000000000000000000000000003734 128.0
HKD1_k127_1645629_3 PFAM Hydantoinase B oxoprolinase K01469,K01474 - 3.5.2.14,3.5.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 533.0
HKD1_k127_1645629_4 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 505.0
HKD1_k127_1645629_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 401.0
HKD1_k127_1645629_6 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 368.0
HKD1_k127_1645629_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 327.0
HKD1_k127_1645629_8 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000009215 293.0
HKD1_k127_1645629_9 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001282 264.0
HKD1_k127_1754185_0 Protein of unknown function (DUF3750) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002815 273.0
HKD1_k127_1754185_1 ornithine cyclodeaminase activity K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.00000007723 56.0
HKD1_k127_1766346_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 505.0
HKD1_k127_1766346_1 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 479.0
HKD1_k127_1766346_2 pfam abc K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 456.0
HKD1_k127_1766346_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 443.0
HKD1_k127_1766346_4 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 422.0
HKD1_k127_1766346_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 323.0
HKD1_k127_1766346_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 298.0
HKD1_k127_1766346_7 PFAM ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 290.0
HKD1_k127_1766346_8 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 298.0
HKD1_k127_1766346_9 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000004161 216.0
HKD1_k127_1773370_0 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001712 288.0
HKD1_k127_1773370_1 alcohol dehydrogenase K00008,K00060 - 1.1.1.103,1.1.1.14 0.0000000000000000000000000000000000000000000000008062 189.0
HKD1_k127_1773370_2 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.000000000000000000000003376 117.0
HKD1_k127_1785339_0 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 596.0
HKD1_k127_1785339_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 545.0
HKD1_k127_1785339_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 479.0
HKD1_k127_1785339_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 374.0
HKD1_k127_1785339_4 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 380.0
HKD1_k127_1785339_5 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 327.0
HKD1_k127_1785339_6 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 285.0
HKD1_k127_1785339_7 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004737 252.0
HKD1_k127_1785339_8 Membrane - - - 0.0000000000000000000000000000000000002202 160.0
HKD1_k127_1794739_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 579.0
HKD1_k127_1794739_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 541.0
HKD1_k127_1794739_10 Pfam:Gp37_Gp68 - - - 0.000003899 48.0
HKD1_k127_1794739_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 396.0
HKD1_k127_1794739_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008072 289.0
HKD1_k127_1794739_4 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000918 241.0
HKD1_k127_1794739_5 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000001234 184.0
HKD1_k127_1794739_6 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000001112 134.0
HKD1_k127_1794739_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000002013 128.0
HKD1_k127_1794739_8 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000001023 111.0
HKD1_k127_1794739_9 PIN domain K07065 - - 0.000000007162 63.0
HKD1_k127_1806627_0 PFAM Tripartite tricarboxylate transporter TctA family K07793 - - 6.452e-245 764.0
HKD1_k127_1806627_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 476.0
HKD1_k127_1806627_2 Short-chain dehydrogenase reductase (SDR) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 368.0
HKD1_k127_1806627_3 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000001811 131.0
HKD1_k127_1824843_0 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 331.0
HKD1_k127_1824843_1 carbamoyl transferase, NodU family K00612,K16035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 325.0
HKD1_k127_1824843_10 COG0451 Nucleoside-diphosphate-sugar epimerases K01710,K01784 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000004749 188.0
HKD1_k127_1824843_11 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000004673 158.0
HKD1_k127_1824843_12 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000006133 113.0
HKD1_k127_1824843_13 Psort location Cytoplasmic, score - - - 0.0000000000000000123 87.0
HKD1_k127_1824843_14 redox protein, regulator of disulfide bond formation K07397 - - 0.0000000000000261 74.0
HKD1_k127_1824843_15 OsmC-like protein K06889,K07397 - - 0.000000001132 60.0
HKD1_k127_1824843_16 Lrp/AsnC ligand binding domain - - - 0.000000002387 62.0
HKD1_k127_1824843_17 Rdx family K07401 - - 0.0001409 46.0
HKD1_k127_1824843_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 295.0
HKD1_k127_1824843_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000302 287.0
HKD1_k127_1824843_4 BtpA family K06971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005827 278.0
HKD1_k127_1824843_5 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001859 276.0
HKD1_k127_1824843_6 PFAM glycoside hydrolase family 3 K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000007599 292.0
HKD1_k127_1824843_7 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00847,K00852 GO:0003674,GO:0003824,GO:0004747,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019303,GO:0019321,GO:0019323,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.15,2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000001448 262.0
HKD1_k127_1824843_8 PFAM Enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000484 253.0
HKD1_k127_1824843_9 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000003143 222.0
HKD1_k127_1842833_0 Endonuclease V K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000185 202.0
HKD1_k127_1842833_2 Gram-negative-bacterium-type cell outer membrane assembly K21572 - - 0.0000005537 62.0
HKD1_k127_1863920_0 AcrB/AcrD/AcrF family - - - 0.0 1176.0
HKD1_k127_1863920_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.263e-268 851.0
HKD1_k127_1863920_10 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 370.0
HKD1_k127_1863920_11 PFAM CorA-like Mg2 transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 350.0
HKD1_k127_1863920_12 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 299.0
HKD1_k127_1863920_13 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002777 279.0
HKD1_k127_1863920_14 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000005288 276.0
HKD1_k127_1863920_15 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003958 283.0
HKD1_k127_1863920_16 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000001438 252.0
HKD1_k127_1863920_17 HlyD family secretion protein K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000008968 249.0
HKD1_k127_1863920_18 Belongs to the UPF0282 family K07022 - - 0.000000000000000000000000000000000000000000000000000000008294 210.0
HKD1_k127_1863920_19 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000006358 189.0
HKD1_k127_1863920_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 7.174e-253 802.0
HKD1_k127_1863920_20 Ppx/GppA phosphatase family K01524 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0040007,GO:0044237,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000001204 207.0
HKD1_k127_1863920_21 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000001658 180.0
HKD1_k127_1863920_22 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000001793 155.0
HKD1_k127_1863920_23 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000007836 125.0
HKD1_k127_1863920_24 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000001948 123.0
HKD1_k127_1863920_25 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.00000000000000000000003522 106.0
HKD1_k127_1863920_26 Redoxin - - - 0.000000000000000003047 87.0
HKD1_k127_1863920_27 Redoxin - - - 0.0000000000122 66.0
HKD1_k127_1863920_28 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000002458 59.0
HKD1_k127_1863920_29 Domain of unknown function (DUF4149) - - - 0.0001216 51.0
HKD1_k127_1863920_3 ABC transporter transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 538.0
HKD1_k127_1863920_4 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009683 496.0
HKD1_k127_1863920_5 secondary active sulfate transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 492.0
HKD1_k127_1863920_6 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 453.0
HKD1_k127_1863920_7 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 389.0
HKD1_k127_1863920_8 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 395.0
HKD1_k127_1863920_9 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 390.0
HKD1_k127_1867401_0 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 482.0
HKD1_k127_1867401_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001727 258.0
HKD1_k127_1867401_2 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000001574 194.0
HKD1_k127_1867401_3 transcriptional regulator, PadR family - - - 0.000000000000000000000000000000000006491 141.0
HKD1_k127_1867401_4 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000001956 131.0
HKD1_k127_1883706_0 Replication initiator protein A - - - 0.0000000000000000000000000000000000000000000000000000003742 208.0
HKD1_k127_1883706_1 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.00000000000000000000000000000000000000000000001328 173.0
HKD1_k127_1929662_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 403.0
HKD1_k127_1929662_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000003313 252.0
HKD1_k127_1929662_2 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003093 237.0
HKD1_k127_1929662_3 cell septum assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000002658 235.0
HKD1_k127_1929662_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000239 204.0
HKD1_k127_1929662_5 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000003528 190.0
HKD1_k127_1929662_6 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000001473 190.0
HKD1_k127_1929662_7 Cold shock protein K03704 - - 0.00000000000000000000000000008613 115.0
HKD1_k127_1929662_8 amine dehydrogenase activity - - - 0.000000001142 65.0
HKD1_k127_1929662_9 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.0000002148 59.0
HKD1_k127_1991296_0 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 504.0
HKD1_k127_1991296_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 492.0
HKD1_k127_1991296_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 446.0
HKD1_k127_1991296_3 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008457 411.0
HKD1_k127_1991296_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000004157 242.0
HKD1_k127_1991296_5 cytosine deaminase K01485 - 3.5.4.1 0.0000000001112 64.0
HKD1_k127_1991296_6 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.00003865 49.0
HKD1_k127_2012017_0 NADP-dependent oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 381.0
HKD1_k127_2012017_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 373.0
HKD1_k127_2012017_2 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 306.0
HKD1_k127_2012017_3 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 291.0
HKD1_k127_2012017_4 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005159 283.0
HKD1_k127_2012017_5 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002031 264.0
HKD1_k127_2012017_6 Putative mono-oxygenase ydhR - - - 0.0000000000000000000000000000000002347 134.0
HKD1_k127_2012017_7 DinB superfamily - - - 0.0000000000000000000223 98.0
HKD1_k127_2012017_8 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000001019 57.0
HKD1_k127_2030491_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 487.0
HKD1_k127_2054239_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1174.0
HKD1_k127_2054239_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 494.0
HKD1_k127_2054239_10 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.00000000000000000000000001104 118.0
HKD1_k127_2054239_11 Ribbon-helix-helix protein, copG family - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000000002419 70.0
HKD1_k127_2054239_2 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 430.0
HKD1_k127_2054239_3 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 361.0
HKD1_k127_2054239_4 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005285 267.0
HKD1_k127_2054239_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000003013 201.0
HKD1_k127_2054239_6 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000002304 191.0
HKD1_k127_2054239_7 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000004163 184.0
HKD1_k127_2054239_8 HDOD domain - - - 0.0000000000000000000000000000001869 136.0
HKD1_k127_2054239_9 Trypsin-like peptidase domain - - - 0.00000000000000000000000000006089 129.0
HKD1_k127_2064783_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 499.0
HKD1_k127_2064783_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 436.0
HKD1_k127_2064783_10 COG4177 ABC-type branched-chain amino acid transport system, permease component - - - 0.000000000000000000000000000000000000000000000000000000003937 219.0
HKD1_k127_2064783_11 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000577 200.0
HKD1_k127_2064783_12 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000166 188.0
HKD1_k127_2064783_13 Phosphonate ABC transporter K02044 - - 0.000000000000000000000000000000000000000000013 179.0
HKD1_k127_2064783_14 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000005155 153.0
HKD1_k127_2064783_15 Alpha/beta hydrolase family - - - 0.0000000000000006797 89.0
HKD1_k127_2064783_16 - - - - 0.00000000000001431 86.0
HKD1_k127_2064783_17 SnoaL-like domain - - - 0.000000001123 62.0
HKD1_k127_2064783_19 Lipopolysaccharide assembly protein A domain - - - 0.00001841 52.0
HKD1_k127_2064783_2 Lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 324.0
HKD1_k127_2064783_3 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 323.0
HKD1_k127_2064783_4 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001666 271.0
HKD1_k127_2064783_5 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002469 273.0
HKD1_k127_2064783_6 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005239 277.0
HKD1_k127_2064783_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004279 279.0
HKD1_k127_2064783_8 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009532 267.0
HKD1_k127_2064783_9 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000009925 258.0
HKD1_k127_2086409_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 416.0
HKD1_k127_2086409_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 385.0
HKD1_k127_2086409_2 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000003416 269.0
HKD1_k127_2086409_3 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000004714 225.0
HKD1_k127_2086409_4 UTRA K03710 - - 0.000000000000000000000000000000000003398 149.0
HKD1_k127_2087955_0 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 443.0
HKD1_k127_2087955_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 397.0
HKD1_k127_2087955_10 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 0.0000000000000000000001166 100.0
HKD1_k127_2087955_11 Belongs to the UPF0312 family - - - 0.000000000000000000006365 105.0
HKD1_k127_2087955_2 PrpF protein K09788 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 372.0
HKD1_k127_2087955_3 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 333.0
HKD1_k127_2087955_4 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 334.0
HKD1_k127_2087955_5 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 329.0
HKD1_k127_2087955_6 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 302.0
HKD1_k127_2087955_7 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008927 279.0
HKD1_k127_2087955_8 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000002147 226.0
HKD1_k127_2087955_9 Sterol carrier protein - - - 0.0000000000000000000000000000000000000001208 153.0
HKD1_k127_2095107_0 AMP-dependent synthetase and ligase K00666 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 588.0
HKD1_k127_2095107_1 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 392.0
HKD1_k127_2095107_2 Conserved Protein - - - 0.000000000000000000000000000000000000000000000000000009785 196.0
HKD1_k127_2095107_3 ribonucleoside-diphosphate reductase activity K07735 - - 0.0000000000000000000000000000000000000000000000002019 186.0
HKD1_k127_2095107_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000000000001263 122.0
HKD1_k127_2095107_5 N-terminal domain of galactosyltransferase - - - 0.0000000000000000000000005809 115.0
HKD1_k127_2095107_6 Protein of unknown function (DUF3303) - - - 0.0000000000000000004699 91.0
HKD1_k127_2095107_7 overlaps another CDS with the same product name - - - 0.000000000000000001634 98.0
HKD1_k127_2095107_8 Phage integrase family - - - 0.0000000000001402 79.0
HKD1_k127_2095107_9 - - - - 0.0000000000194 70.0
HKD1_k127_2112297_0 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 6.864e-312 989.0
HKD1_k127_2112297_1 Peptide ABC transporter substrate-binding protein K02035 - - 2.033e-285 886.0
HKD1_k127_2112297_2 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000003797 253.0
HKD1_k127_2112297_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000008545 190.0
HKD1_k127_2117093_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 0.0 1073.0
HKD1_k127_2117093_1 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 8.422e-201 642.0
HKD1_k127_2117093_10 Phosphoenolpyruvate hydrolase-like - - - 0.00000000003235 68.0
HKD1_k127_2117093_11 PFAM Ankyrin K21440 - - 0.00000000007636 75.0
HKD1_k127_2117093_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 357.0
HKD1_k127_2117093_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 338.0
HKD1_k127_2117093_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000009457 254.0
HKD1_k127_2117093_5 Abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000001201 252.0
HKD1_k127_2117093_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000001473 223.0
HKD1_k127_2117093_7 Haem-degrading - - - 0.0000000000000000000000000000000000000156 150.0
HKD1_k127_2117093_8 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000004599 136.0
HKD1_k127_2117093_9 GYD domain - - - 0.000000000000000000000000006383 113.0
HKD1_k127_2118960_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0 1275.0
HKD1_k127_2118960_1 Gp5 C-terminal repeat (3 copies) K11904 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 537.0
HKD1_k127_2118960_2 Pfam:T6SS_VasB K11895 - - 0.00005159 46.0
HKD1_k127_2133941_0 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 340.0
HKD1_k127_2133941_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000001013 259.0
HKD1_k127_2133941_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000001285 195.0
HKD1_k127_2133941_3 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000006433 146.0
HKD1_k127_2133941_4 - - - - 0.000000000000000000001741 104.0
HKD1_k127_2133941_5 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.00003837 49.0
HKD1_k127_2139903_0 Transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006277 252.0
HKD1_k127_2139903_1 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000003188 229.0
HKD1_k127_2146697_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 4.46e-198 634.0
HKD1_k127_2146697_1 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 365.0
HKD1_k127_2146697_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000005728 148.0
HKD1_k127_2146697_11 - - - - 0.00000000000001261 87.0
HKD1_k127_2146697_12 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000006833 62.0
HKD1_k127_2146697_2 PFAM Transketolase K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 355.0
HKD1_k127_2146697_3 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 334.0
HKD1_k127_2146697_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 331.0
HKD1_k127_2146697_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 326.0
HKD1_k127_2146697_6 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 295.0
HKD1_k127_2146697_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002907 273.0
HKD1_k127_2146697_8 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000007785 178.0
HKD1_k127_2146697_9 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000001711 168.0
HKD1_k127_2148757_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 372.0
HKD1_k127_2148757_1 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006537 350.0
HKD1_k127_2148757_2 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001342 282.0
HKD1_k127_2156144_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 2.932e-231 740.0
HKD1_k127_2156144_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 634.0
HKD1_k127_2156144_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 331.0
HKD1_k127_2156144_11 AMP-binding enzyme K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 341.0
HKD1_k127_2156144_12 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 305.0
HKD1_k127_2156144_13 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 301.0
HKD1_k127_2156144_14 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 297.0
HKD1_k127_2156144_15 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000191 285.0
HKD1_k127_2156144_16 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000203 198.0
HKD1_k127_2156144_17 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000006542 156.0
HKD1_k127_2156144_18 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000327 111.0
HKD1_k127_2156144_19 Translation initiation factor SUI1 K03113 - - 0.000000000000000000000002028 117.0
HKD1_k127_2156144_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 598.0
HKD1_k127_2156144_20 lactoylglutathione lyase activity - - - 0.000000000000000000000004936 102.0
HKD1_k127_2156144_21 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000001322 113.0
HKD1_k127_2156144_22 ABC transporter substrate binding protein K01989 - - 0.000000000000000000003122 96.0
HKD1_k127_2156144_23 ABC transporter substrate binding protein K01989 - - 0.0000000000007114 70.0
HKD1_k127_2156144_24 ABC transporter substrate binding protein K01989 - - 0.00000000001761 66.0
HKD1_k127_2156144_25 protein, possibly involved in aromatic compounds catabolism - - - 0.000000001473 67.0
HKD1_k127_2156144_26 Lipid A biosynthesis K02517 - 2.3.1.241 0.00003416 55.0
HKD1_k127_2156144_27 acyl carrier protein - - - 0.0002384 51.0
HKD1_k127_2156144_28 DinB superfamily - - - 0.0007783 46.0
HKD1_k127_2156144_29 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0009174 44.0
HKD1_k127_2156144_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 593.0
HKD1_k127_2156144_4 mandelate racemase muconate lactonizing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009272 533.0
HKD1_k127_2156144_5 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 465.0
HKD1_k127_2156144_6 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 403.0
HKD1_k127_2156144_7 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 383.0
HKD1_k127_2156144_8 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 371.0
HKD1_k127_2156144_9 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 351.0
HKD1_k127_2164021_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 1.576e-285 884.0
HKD1_k127_2164021_1 Gamma-glutamyltranspeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 373.0
HKD1_k127_2164021_10 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000843 90.0
HKD1_k127_2164021_11 - - - - 0.0000000000001278 72.0
HKD1_k127_2164021_13 Luciferase-like monooxygenase - - - 0.0003504 44.0
HKD1_k127_2164021_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 343.0
HKD1_k127_2164021_3 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004815 286.0
HKD1_k127_2164021_4 PFAM Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002474 269.0
HKD1_k127_2164021_5 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000003015 234.0
HKD1_k127_2164021_6 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000000233 228.0
HKD1_k127_2164021_7 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000006048 192.0
HKD1_k127_2164021_8 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000002146 152.0
HKD1_k127_2164021_9 ChrR Cupin-like domain - - - 0.0000000000000000000000000000007146 127.0
HKD1_k127_2165318_0 TIM-barrel fold - - - 3.766e-198 635.0
HKD1_k127_2165318_1 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 554.0
HKD1_k127_2165318_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001417 283.0
HKD1_k127_2165318_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000006619 219.0
HKD1_k127_2165318_4 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00179,K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000001712 179.0
HKD1_k127_2165318_5 cephalosporin hydroxylase - - - 0.00000000000000000000000000000000000000005594 168.0
HKD1_k127_2165318_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000003643 118.0
HKD1_k127_2165318_7 methyltransferase K16648 - - 0.00000000000000000000004685 113.0
HKD1_k127_2165318_8 DinB superfamily - - - 0.00000000000000000001955 100.0
HKD1_k127_2165318_9 Glycosyltransferase, group 2 family protein - - - 0.000000003857 67.0
HKD1_k127_2166754_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.0 1046.0
HKD1_k127_2166754_1 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 526.0
HKD1_k127_2166754_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000006233 231.0
HKD1_k127_2166754_11 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000811 216.0
HKD1_k127_2166754_12 NAD dependent epimerase dehydratase family - - - 0.000000000000000000000000000000000000000000000000000004166 204.0
HKD1_k127_2166754_13 peptidase activity, acting on L-amino acid peptides - - - 0.00000000000000000000000000000000000000000000000000005388 203.0
HKD1_k127_2166754_14 COG2801 Transposase and inactivated derivatives K07497 GO:0008150,GO:0009987,GO:0032196 - 0.000000000000000000000000000000000000000000000000008151 189.0
HKD1_k127_2166754_15 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000003331 203.0
HKD1_k127_2166754_16 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000003805 194.0
HKD1_k127_2166754_17 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000001566 184.0
HKD1_k127_2166754_18 thiolester hydrolase activity K17362 - - 0.0000000000000000000000000000000001599 138.0
HKD1_k127_2166754_19 Amidohydrolase K07045 - - 0.000000000000000000000000000000001655 143.0
HKD1_k127_2166754_2 Beta-lactamase K18372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 527.0
HKD1_k127_2166754_21 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000000000000223 109.0
HKD1_k127_2166754_22 Pfam Methyltransferase - - - 0.000000000000000000007227 109.0
HKD1_k127_2166754_23 PIN domain - - - 0.00000000000000000006521 98.0
HKD1_k127_2166754_24 Uncharacterised nucleotidyltransferase - - - 0.00000000000000001795 97.0
HKD1_k127_2166754_25 Nucleotidyltransferase domain K07075 - - 0.00000000000001506 81.0
HKD1_k127_2166754_26 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000004962 72.0
HKD1_k127_2166754_27 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000003618 58.0
HKD1_k127_2166754_29 phytanoyl-CoA dioxygenase - - - 0.0008021 51.0
HKD1_k127_2166754_3 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 468.0
HKD1_k127_2166754_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 479.0
HKD1_k127_2166754_5 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 414.0
HKD1_k127_2166754_6 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 392.0
HKD1_k127_2166754_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 349.0
HKD1_k127_2166754_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase K11945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009843 267.0
HKD1_k127_2166754_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001426 257.0
HKD1_k127_2205333_0 Proton-conducting membrane transporter K00342,K05575 - 1.6.5.3 1.885e-198 656.0
HKD1_k127_2205333_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 577.0
HKD1_k127_2205333_10 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000004438 222.0
HKD1_k127_2205333_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000001294 217.0
HKD1_k127_2205333_12 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.00000000000000000000000000000000000000000000001298 176.0
HKD1_k127_2205333_13 4Fe-4S dicluster domain K00338,K02573,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000002303 146.0
HKD1_k127_2205333_14 Bacterial transcriptional repressor C-terminal K16137 - - 0.000000000000000000000000000000000006561 145.0
HKD1_k127_2205333_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000002789 147.0
HKD1_k127_2205333_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.0000000000000000000000000000001841 127.0
HKD1_k127_2205333_17 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000003698 127.0
HKD1_k127_2205333_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000008465 123.0
HKD1_k127_2205333_19 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.000000000000000000000000002002 117.0
HKD1_k127_2205333_2 NADH-quinone oxidoreductase chain L K00341,K05577 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 560.0
HKD1_k127_2205333_20 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000008645 104.0
HKD1_k127_2205333_21 - - - - 0.000000000000000000005434 94.0
HKD1_k127_2205333_22 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339,K05578 - 1.6.5.3 0.000000000000000001762 97.0
HKD1_k127_2205333_3 NAD binding K00333,K05579,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 462.0
HKD1_k127_2205333_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343,K05573 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007508 432.0
HKD1_k127_2205333_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 383.0
HKD1_k127_2205333_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 372.0
HKD1_k127_2205333_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 318.0
HKD1_k127_2205333_8 NIPSNAP - - - 0.000000000000000000000000000000000000000000000000000000000000001586 224.0
HKD1_k127_2205333_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000005594 226.0
HKD1_k127_2220481_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 GO:0003674,GO:0003824,GO:0004321,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0071944 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 599.0
HKD1_k127_2220481_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 381.0
HKD1_k127_2220481_10 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000000000004058 131.0
HKD1_k127_2220481_11 PFAM Carbohydrate-selective porin OprB K07267 - - 0.000000000000000000000000000002595 125.0
HKD1_k127_2220481_12 - - - - 0.0000000000000000000000000005313 121.0
HKD1_k127_2220481_13 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000321 111.0
HKD1_k127_2220481_14 Ion channel - - - 0.000000000000000002689 94.0
HKD1_k127_2220481_15 membrane - - - 0.00000000000457 68.0
HKD1_k127_2220481_16 Integral membrane protein TerC family - - - 0.0000000000137 76.0
HKD1_k127_2220481_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 303.0
HKD1_k127_2220481_3 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000003155 235.0
HKD1_k127_2220481_4 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000009052 239.0
HKD1_k127_2220481_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000004638 205.0
HKD1_k127_2220481_6 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000000000000005978 201.0
HKD1_k127_2220481_7 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000001996 176.0
HKD1_k127_2220481_8 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000005642 164.0
HKD1_k127_2220481_9 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000224 138.0
HKD1_k127_2224580_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1651.0
HKD1_k127_2224580_1 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 7.556e-264 827.0
HKD1_k127_2224580_10 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000007685 263.0
HKD1_k127_2224580_11 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004677 255.0
HKD1_k127_2224580_12 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000005513 217.0
HKD1_k127_2224580_13 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000195 215.0
HKD1_k127_2224580_14 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K19647 - 1.1.1.291,1.1.1.31 0.0000000000000000000000000000000000000000000000005645 188.0
HKD1_k127_2224580_15 PIN domain - - - 0.00000000000000000000004912 100.0
HKD1_k127_2224580_16 YacP-like NYN domain K06962 - - 0.000000000001102 75.0
HKD1_k127_2224580_2 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 512.0
HKD1_k127_2224580_3 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 481.0
HKD1_k127_2224580_4 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009624 489.0
HKD1_k127_2224580_5 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 469.0
HKD1_k127_2224580_6 Family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 341.0
HKD1_k127_2224580_7 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008479 292.0
HKD1_k127_2224580_8 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001985 289.0
HKD1_k127_2224580_9 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002671 280.0
HKD1_k127_2233728_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 8.586e-280 869.0
HKD1_k127_2233728_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 519.0
HKD1_k127_2233728_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001187 296.0
HKD1_k127_2233728_3 PFAM import inner membrane translocase, subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000552 263.0
HKD1_k127_2233728_4 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000002078 245.0
HKD1_k127_2233728_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000001168 200.0
HKD1_k127_2233728_6 Histidine kinase - - - 0.000000000000000000000000000000000000000001328 179.0
HKD1_k127_2233728_7 PFAM thiamineS protein - - - 0.00000001691 59.0
HKD1_k127_2233728_8 BlaR1 peptidase M56 - - - 0.0000001415 59.0
HKD1_k127_2246537_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 1.377e-223 711.0
HKD1_k127_2246537_1 Biotin carboxylase C-terminal domain K01965,K01968 - 6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 576.0
HKD1_k127_2246537_11 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin - - - 0.00000003057 67.0
HKD1_k127_2246537_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 451.0
HKD1_k127_2246537_3 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 378.0
HKD1_k127_2246537_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000009928 249.0
HKD1_k127_2246537_5 PFAM Vitamin K epoxide reductase - - - 0.00000000000000000000000963 108.0
HKD1_k127_2246537_6 Outer membrane efflux protein - - - 0.00000000000000000455 90.0
HKD1_k127_2246537_7 Vitamin k epoxide reductase - - - 0.0000000000000002646 80.0
HKD1_k127_2246537_8 Protein of unknown function (DUF2892) - - - 0.0000000000005808 79.0
HKD1_k127_2250435_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 4.171e-220 698.0
HKD1_k127_2250435_1 Glucose / Sorbosone dehydrogenase - - - 4.411e-210 671.0
HKD1_k127_2250435_10 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.000000000000000000000003263 104.0
HKD1_k127_2250435_11 Protein of unknown function (DUF1232) - - - 0.000000000000007002 79.0
HKD1_k127_2250435_12 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000001012 56.0
HKD1_k127_2250435_13 Beta-lactamase superfamily domain - - - 0.00000023 55.0
HKD1_k127_2250435_14 PBS lyase HEAT-like repeat - - - 0.000005439 58.0
HKD1_k127_2250435_2 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 509.0
HKD1_k127_2250435_3 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 481.0
HKD1_k127_2250435_4 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 415.0
HKD1_k127_2250435_5 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 369.0
HKD1_k127_2250435_6 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 340.0
HKD1_k127_2250435_7 GTPase activity K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 315.0
HKD1_k127_2250435_8 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 322.0
HKD1_k127_2250435_9 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000002446 194.0
HKD1_k127_2285848_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000002217 173.0
HKD1_k127_2285848_1 domain, Protein - - - 0.000000001865 70.0
HKD1_k127_2315613_0 elongation factor G K02355 - - 3.611e-234 743.0
HKD1_k127_2315613_1 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 1.434e-223 711.0
HKD1_k127_2315613_10 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 372.0
HKD1_k127_2315613_11 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 318.0
HKD1_k127_2315613_12 ABC-type transport system involved in resistance to organic solvents permease component K02066 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 317.0
HKD1_k127_2315613_13 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 309.0
HKD1_k127_2315613_14 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 308.0
HKD1_k127_2315613_15 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 291.0
HKD1_k127_2315613_16 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002491 289.0
HKD1_k127_2315613_17 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009383 271.0
HKD1_k127_2315613_18 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005272 266.0
HKD1_k127_2315613_19 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000006451 250.0
HKD1_k127_2315613_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 585.0
HKD1_k127_2315613_20 - - - - 0.000000000000000000000000000000000000000000000000000000000003691 228.0
HKD1_k127_2315613_21 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000001097 204.0
HKD1_k127_2315613_22 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000001478 199.0
HKD1_k127_2315613_23 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000000000000000000006514 205.0
HKD1_k127_2315613_24 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000007628 181.0
HKD1_k127_2315613_25 - K07092 - - 0.000000000000000000000000000000000000000000006401 169.0
HKD1_k127_2315613_26 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000279 174.0
HKD1_k127_2315613_27 - - - - 0.00000000000000000001133 95.0
HKD1_k127_2315613_28 DNA-binding transcription factor activity K03892 - - 0.0000000000000000001435 93.0
HKD1_k127_2315613_29 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000002962 91.0
HKD1_k127_2315613_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 578.0
HKD1_k127_2315613_30 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00992 - 2.7.7.99 0.00000000000001616 86.0
HKD1_k127_2315613_31 adenosylhomocysteine nucleosidase activity K01243,K03527 - 1.17.7.4,3.2.2.9 0.000000001476 70.0
HKD1_k127_2315613_4 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 570.0
HKD1_k127_2315613_5 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 515.0
HKD1_k127_2315613_6 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 462.0
HKD1_k127_2315613_7 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 378.0
HKD1_k127_2315613_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 392.0
HKD1_k127_2315613_9 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 359.0
HKD1_k127_2315878_0 Belongs to the GcvT family K19191 - 1.5.3.19 2.235e-307 958.0
HKD1_k127_2315878_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.297e-215 680.0
HKD1_k127_2315878_10 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003346 255.0
HKD1_k127_2315878_11 Transcriptional regulator K03724 - - 0.000000000000000000000000000000000000000000000000000003089 196.0
HKD1_k127_2315878_12 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000001745 198.0
HKD1_k127_2315878_13 4Fe-4S binding domain K05524 - - 0.000000000000000000000000000000000000605 140.0
HKD1_k127_2315878_14 Acetyltransferase (GNAT) domain - - - 0.000000000000000001491 98.0
HKD1_k127_2315878_15 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0003381 48.0
HKD1_k127_2315878_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 517.0
HKD1_k127_2315878_3 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 466.0
HKD1_k127_2315878_4 Oligopeptide/dipeptide transporter, C-terminal region K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 456.0
HKD1_k127_2315878_5 Oligopeptide/dipeptide transporter, C-terminal region K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 432.0
HKD1_k127_2315878_6 Belongs to the HAD-like hydrolase superfamily. PhnX family K05306 - 3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 430.0
HKD1_k127_2315878_7 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 412.0
HKD1_k127_2315878_8 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 367.0
HKD1_k127_2315878_9 Aminotransferase K03430 - 2.6.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 311.0
HKD1_k127_2327098_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.02e-236 740.0
HKD1_k127_2327098_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 412.0
HKD1_k127_2327098_2 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000007154 113.0
HKD1_k127_233965_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 501.0
HKD1_k127_233965_1 - - - - 0.0000006531 55.0
HKD1_k127_233965_2 PFAM Septum formation initiator K05589 - - 0.000001846 60.0
HKD1_k127_233965_3 Curdlan synthase K00694 - 2.4.1.12 0.0002057 54.0
HKD1_k127_2345483_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 5.381e-266 846.0
HKD1_k127_2345483_1 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 321.0
HKD1_k127_2345483_10 endonuclease activity - - - 0.000000000000000000000000000000000000000004947 165.0
HKD1_k127_2345483_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000002083 97.0
HKD1_k127_2345483_12 Glutathione peroxidase - - - 0.00000000000002237 76.0
HKD1_k127_2345483_13 peroxiredoxin activity K03564 - 1.11.1.15 0.000000001809 63.0
HKD1_k127_2345483_14 Thioredoxin-like - - - 0.00000352 59.0
HKD1_k127_2345483_15 Alkyl hydroperoxide reductase - - - 0.000005076 51.0
HKD1_k127_2345483_2 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000008031 280.0
HKD1_k127_2345483_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000195 260.0
HKD1_k127_2345483_4 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006568 261.0
HKD1_k127_2345483_5 Belongs to the enoyl-CoA hydratase isomerase family K16880 - - 0.00000000000000000000000000000000000000000000000000000000000000000001582 253.0
HKD1_k127_2345483_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000008506 236.0
HKD1_k127_2345483_7 COG COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000004045 210.0
HKD1_k127_2345483_8 PFAM ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000729 200.0
HKD1_k127_2345483_9 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000004854 192.0
HKD1_k127_2387888_0 GlcNAc-PI de-N-acetylase - - - 1.545e-299 942.0
HKD1_k127_2387888_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 6.805e-265 827.0
HKD1_k127_2387888_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 1.577e-260 814.0
HKD1_k127_2387888_3 PFAM glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 460.0
HKD1_k127_2387888_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 349.0
HKD1_k127_2387888_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 345.0
HKD1_k127_2387888_6 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 296.0
HKD1_k127_2387888_7 DinB family - - - 0.00000000000000005919 90.0
HKD1_k127_2388882_0 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 601.0
HKD1_k127_2388882_1 Acyl-CoA dehydrogenase, N-terminal domain K00248,K00249,K18244 - 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 559.0
HKD1_k127_2388882_10 ABC transporter substrate binding protein K01989 - - 0.000000009564 56.0
HKD1_k127_2388882_11 Ribbon-helix-helix protein, copG family - - - 0.00000002458 59.0
HKD1_k127_2388882_12 Nucleotidyltransferase domain - - - 0.0000126 52.0
HKD1_k127_2388882_13 LysR family - - - 0.0007058 43.0
HKD1_k127_2388882_2 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 453.0
HKD1_k127_2388882_3 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 396.0
HKD1_k127_2388882_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000196 255.0
HKD1_k127_2388882_5 Methylmuconolactone methyl-isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000009469 219.0
HKD1_k127_2388882_6 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000009875 192.0
HKD1_k127_2388882_7 HEPN domain - - - 0.0000000000000000000000000000000000001098 152.0
HKD1_k127_2388882_8 TIGRFAM Methylglyoxal synthase K01734 - 4.2.3.3 0.0000000000000000000002443 98.0
HKD1_k127_2388882_9 ribonuclease activity - - - 0.0000000000000000009571 94.0
HKD1_k127_2402989_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1014.0
HKD1_k127_2402989_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 6.969e-275 871.0
HKD1_k127_2402989_10 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 323.0
HKD1_k127_2402989_11 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 302.0
HKD1_k127_2402989_12 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 295.0
HKD1_k127_2402989_13 Trypsin-like serine protease K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 300.0
HKD1_k127_2402989_14 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003434 281.0
HKD1_k127_2402989_15 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001204 260.0
HKD1_k127_2402989_16 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000001433 257.0
HKD1_k127_2402989_17 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000002729 237.0
HKD1_k127_2402989_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002866 228.0
HKD1_k127_2402989_19 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000001046 220.0
HKD1_k127_2402989_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 3.233e-248 773.0
HKD1_k127_2402989_20 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000006404 203.0
HKD1_k127_2402989_21 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000983 203.0
HKD1_k127_2402989_22 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000001014 186.0
HKD1_k127_2402989_23 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.00000000000000000000000000000000000000000006154 172.0
HKD1_k127_2402989_24 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000001192 182.0
HKD1_k127_2402989_25 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000004116 156.0
HKD1_k127_2402989_26 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000003306 151.0
HKD1_k127_2402989_27 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000001283 151.0
HKD1_k127_2402989_28 viral genome integration into host DNA - - - 0.00000000000000000000000000001498 121.0
HKD1_k127_2402989_29 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657,K18941 - - 0.00000000000000000000000000002989 121.0
HKD1_k127_2402989_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 9.98e-248 771.0
HKD1_k127_2402989_30 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000004079 124.0
HKD1_k127_2402989_31 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000003032 113.0
HKD1_k127_2402989_32 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000224 107.0
HKD1_k127_2402989_33 PFAM N-formylglutamate amidohydrolase - - - 0.00000000000000000000009453 109.0
HKD1_k127_2402989_34 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000001492 98.0
HKD1_k127_2402989_35 SnoaL-like polyketide cyclase - - - 0.0000000000000000002476 93.0
HKD1_k127_2402989_36 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000004031 88.0
HKD1_k127_2402989_37 Belongs to the 'phage' integrase family K14059 - - 0.0000000000000635 79.0
HKD1_k127_2402989_38 - - - - 0.000000000001365 70.0
HKD1_k127_2402989_39 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000001161 66.0
HKD1_k127_2402989_4 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K16872 - 2.3.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 578.0
HKD1_k127_2402989_40 Belongs to the 'phage' integrase family K14059 - - 0.000000001916 66.0
HKD1_k127_2402989_41 - - - - 0.000000004625 67.0
HKD1_k127_2402989_42 Protein of unknown function (DUF507) - - - 0.0000001062 57.0
HKD1_k127_2402989_43 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000302 56.0
HKD1_k127_2402989_45 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00005604 53.0
HKD1_k127_2402989_46 Protein of unknown function (DUF507) K09804 - - 0.0001038 51.0
HKD1_k127_2402989_5 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 522.0
HKD1_k127_2402989_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 474.0
HKD1_k127_2402989_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 434.0
HKD1_k127_2402989_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 377.0
HKD1_k127_2402989_9 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 374.0
HKD1_k127_241063_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 424.0
HKD1_k127_241063_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 384.0
HKD1_k127_241063_2 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000008036 249.0
HKD1_k127_241063_3 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000005577 223.0
HKD1_k127_241063_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000001172 222.0
HKD1_k127_241063_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000001113 190.0
HKD1_k127_241063_6 - - - - 0.0000000000000003111 81.0
HKD1_k127_241063_7 SnoaL-like domain - - - 0.000000000000003999 82.0
HKD1_k127_2411760_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.458e-227 746.0
HKD1_k127_2411760_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 7.668e-225 729.0
HKD1_k127_2411760_2 PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 435.0
HKD1_k127_2411760_3 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 331.0
HKD1_k127_2411760_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001352 245.0
HKD1_k127_2411760_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000002709 226.0
HKD1_k127_2411760_6 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000001902 120.0
HKD1_k127_2423579_0 Hydroxymethylglutaryl-coenzyme A reductase K00021 - 1.1.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 415.0
HKD1_k127_2423579_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - 0.0000000000000000000000000000000000000000000000000000000000000000007801 238.0
HKD1_k127_2423579_2 Diacylglycerol kinase K07029 GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.107 0.000000000000000000000000000000000000000000000000006514 201.0
HKD1_k127_2428151_0 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 576.0
HKD1_k127_2428151_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 362.0
HKD1_k127_2428151_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 323.0
HKD1_k127_2428151_3 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000137 283.0
HKD1_k127_2428151_4 BFD domain protein 2Fe-2S -binding domain protein - - - 0.000000000000000000000000000000000003149 143.0
HKD1_k127_2442354_0 PFAM Basic membrane K02058,K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 554.0
HKD1_k127_2442354_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 554.0
HKD1_k127_2442354_10 Belongs to the CinA family - - - 0.0000000000000000000000000000000000000000000000000000000001762 209.0
HKD1_k127_2442354_11 acetyltransferase K19113 - - 0.000000000000000000000000000000000000000000000006666 184.0
HKD1_k127_2442354_12 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000002866 179.0
HKD1_k127_2442354_13 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000004813 173.0
HKD1_k127_2442354_14 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000001559 153.0
HKD1_k127_2442354_15 Belongs to the UPF0306 family K09979 - - 0.0000000000000000000000989 103.0
HKD1_k127_2442354_16 HMGL-like K01640 - 4.1.3.4 0.000000005052 59.0
HKD1_k127_2442354_17 nucleotidyltransferase activity K00984,K19279 - 2.7.7.47 0.000008338 49.0
HKD1_k127_2442354_18 PFAM Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.00001409 51.0
HKD1_k127_2442354_2 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 490.0
HKD1_k127_2442354_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 447.0
HKD1_k127_2442354_4 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 414.0
HKD1_k127_2442354_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 346.0
HKD1_k127_2442354_6 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 359.0
HKD1_k127_2442354_7 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 317.0
HKD1_k127_2442354_8 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 301.0
HKD1_k127_2442354_9 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000003464 221.0
HKD1_k127_2460959_0 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 572.0
HKD1_k127_2460959_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 550.0
HKD1_k127_2460959_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000001399 149.0
HKD1_k127_2460959_11 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000002373 159.0
HKD1_k127_2460959_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000004887 111.0
HKD1_k127_2460959_13 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000004074 103.0
HKD1_k127_2460959_15 Psort location Cytoplasmic, score K00705 - 2.4.1.25 0.0002285 53.0
HKD1_k127_2460959_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 527.0
HKD1_k127_2460959_3 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 457.0
HKD1_k127_2460959_4 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 383.0
HKD1_k127_2460959_5 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 327.0
HKD1_k127_2460959_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000785 246.0
HKD1_k127_2460959_7 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000002768 219.0
HKD1_k127_2460959_8 Acyclic terpene utilisation family protein AtuA - - - 0.0000000000000000000000000000000000000000000000002686 183.0
HKD1_k127_2460959_9 lactate racemase activity - - - 0.000000000000000000000000000000000000000002238 176.0
HKD1_k127_246241_0 1,4-alpha-glucan branching enzyme activity K00700,K01236 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.141 0.0 1028.0
HKD1_k127_246241_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 4.742e-278 873.0
HKD1_k127_246241_10 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 444.0
HKD1_k127_246241_11 Amidohydrolase family K15358 - 3.5.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 443.0
HKD1_k127_246241_12 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 419.0
HKD1_k127_246241_13 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 400.0
HKD1_k127_246241_14 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 379.0
HKD1_k127_246241_15 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 346.0
HKD1_k127_246241_16 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 327.0
HKD1_k127_246241_17 Proteasome subunit K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 306.0
HKD1_k127_246241_18 Proteasome subunit K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 297.0
HKD1_k127_246241_19 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 289.0
HKD1_k127_246241_2 Proteasomal ATPase OB/ID domain K07184,K07777,K12065,K13525,K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 2.7.13.3 2.155e-236 747.0
HKD1_k127_246241_20 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002246 303.0
HKD1_k127_246241_21 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001125 278.0
HKD1_k127_246241_22 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000008209 274.0
HKD1_k127_246241_23 Amino acid synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006089 255.0
HKD1_k127_246241_24 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000001301 252.0
HKD1_k127_246241_25 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000008755 238.0
HKD1_k127_246241_26 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000253 216.0
HKD1_k127_246241_27 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000003474 194.0
HKD1_k127_246241_28 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000005059 184.0
HKD1_k127_246241_29 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000003631 183.0
HKD1_k127_246241_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 624.0
HKD1_k127_246241_30 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000002233 137.0
HKD1_k127_246241_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 617.0
HKD1_k127_246241_5 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 595.0
HKD1_k127_246241_6 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008762 580.0
HKD1_k127_246241_7 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 518.0
HKD1_k127_246241_8 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 490.0
HKD1_k127_246241_9 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 493.0
HKD1_k127_2491521_0 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 454.0
HKD1_k127_2491521_1 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 339.0
HKD1_k127_2491521_2 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 336.0
HKD1_k127_2491521_3 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000002376 233.0
HKD1_k127_2491521_4 Protein conserved in bacteria K06320 - - 0.000000000000000000000000000000000001347 153.0
HKD1_k127_2491521_5 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.00003922 47.0
HKD1_k127_2527168_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002259 280.0
HKD1_k127_2527168_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006644 265.0
HKD1_k127_2541736_0 PFAM Acetamidase Formamidase K01455 - 3.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 334.0
HKD1_k127_2541736_1 ornithine cyclodeaminase activity K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 309.0
HKD1_k127_2541736_2 hydratase decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000002705 213.0
HKD1_k127_2541736_3 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000004663 136.0
HKD1_k127_2541736_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000003507 95.0
HKD1_k127_2541736_5 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000001175 82.0
HKD1_k127_2541736_6 nucleotidyltransferase activity K07076 - - 0.000000000347 66.0
HKD1_k127_2553303_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 361.0
HKD1_k127_2553303_1 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 344.0
HKD1_k127_2553303_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 349.0
HKD1_k127_2553303_3 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000353 250.0
HKD1_k127_2568030_0 Glycogen debranching enzyme - - - 0.0 1533.0
HKD1_k127_2568030_1 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 334.0
HKD1_k127_2568030_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 313.0
HKD1_k127_2568030_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000001196 190.0
HKD1_k127_2568030_4 Bacterial periplasmic substrate-binding proteins K10039 - - 0.000000000000000000000000000000001892 148.0
HKD1_k127_2568030_5 Predicted membrane protein (DUF2254) - - - 0.00000000000000000000001989 102.0
HKD1_k127_2624186_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 7.194e-216 689.0
HKD1_k127_2624186_1 PFAM Cytochrome c assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 559.0
HKD1_k127_2624186_10 subunit of a heme lyase K02200 - - 0.000000000000000000000001073 118.0
HKD1_k127_2624186_11 Aldolase/RraA - - - 0.0000000000005997 70.0
HKD1_k127_2624186_12 PFAM Tetratricopeptide repeat - - - 0.000001996 61.0
HKD1_k127_2624186_2 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 509.0
HKD1_k127_2624186_3 Iron deficiency-induced protein A K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 366.0
HKD1_k127_2624186_4 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000002562 245.0
HKD1_k127_2624186_5 Thioredoxin-like K02199,K03671 - - 0.000000000000000000000000000000000000000000000000000003924 216.0
HKD1_k127_2624186_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000001003 198.0
HKD1_k127_2624186_7 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.00000000000000000000000000000000000000000000001277 196.0
HKD1_k127_2624186_8 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000000000000000000000000000000000007434 170.0
HKD1_k127_2624186_9 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000008143 143.0
HKD1_k127_2687550_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 387.0
HKD1_k127_2687550_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 319.0
HKD1_k127_2687550_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001864 269.0
HKD1_k127_2687550_3 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007068 276.0
HKD1_k127_2687550_4 (Rhomboid) family K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000000004135 242.0
HKD1_k127_2687550_5 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000004569 249.0
HKD1_k127_2687550_6 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000003187 226.0
HKD1_k127_2747205_0 Ethanolamine utilization protein EutJ K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 344.0
HKD1_k127_2747205_1 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 325.0
HKD1_k127_2747205_10 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.0000000000000000000152 105.0
HKD1_k127_2747205_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 303.0
HKD1_k127_2747205_3 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 289.0
HKD1_k127_2747205_4 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004604 270.0
HKD1_k127_2747205_5 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000001604 255.0
HKD1_k127_2747205_6 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002204 238.0
HKD1_k127_2747205_7 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000005449 231.0
HKD1_k127_2747205_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000007628 202.0
HKD1_k127_2747205_9 NIPSNAP - - - 0.000000000000000000000000000005946 125.0
HKD1_k127_2770305_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 2.544e-194 633.0
HKD1_k127_2770305_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 461.0
HKD1_k127_2770305_2 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007653 272.0
HKD1_k127_2770305_3 cobalamin binding - - - 0.00000000000000000000000000000000000000004213 158.0
HKD1_k127_2770305_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000007986 162.0
HKD1_k127_2770305_5 3-hydroxyanthranilate 3,4-dioxygenase activity - - - 0.000000000000000000000000000000000000004361 151.0
HKD1_k127_2770305_6 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000001163 84.0
HKD1_k127_2770305_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.000005464 55.0
HKD1_k127_2812691_0 Transglycosylase K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 586.0
HKD1_k127_2812691_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 574.0
HKD1_k127_2812691_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 472.0
HKD1_k127_2812691_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004643 284.0
HKD1_k127_2812691_4 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.0000000000000000000000000000001547 142.0
HKD1_k127_2903028_0 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) - - - 0.0000000000000000000000000002133 129.0
HKD1_k127_2903028_1 DNA-binding transcription factor activity K22298 - - 0.00000000000000000000000005126 110.0
HKD1_k127_2903028_3 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000116 108.0
HKD1_k127_2903028_4 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000007024 85.0
HKD1_k127_2903028_5 - - - - 0.0000000000002662 72.0
HKD1_k127_2903028_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000008954 52.0
HKD1_k127_2903028_7 Luciferase-like monooxygenase - - - 0.00002997 47.0
HKD1_k127_2956794_0 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 586.0
HKD1_k127_2956794_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 569.0
HKD1_k127_2956794_2 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 367.0
HKD1_k127_2956794_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 345.0
HKD1_k127_2956794_4 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 299.0
HKD1_k127_2956794_5 ImpA, N-terminal, type VI secretion system K11902 - - 0.0000000000000000000000000000000000000000000000146 181.0
HKD1_k127_2956794_6 Serine threonine protein kinase - - - 0.00000001919 59.0
HKD1_k127_2960588_0 choline dehydrogenase activity - - - 3.5e-284 880.0
HKD1_k127_2960588_1 Adenylate and Guanylate cyclase catalytic domain - - - 3.006e-225 707.0
HKD1_k127_2960588_10 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001968 286.0
HKD1_k127_2960588_11 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001369 269.0
HKD1_k127_2960588_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002131 259.0
HKD1_k127_2960588_13 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000002844 232.0
HKD1_k127_2960588_14 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000005167 208.0
HKD1_k127_2960588_15 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000002144 203.0
HKD1_k127_2960588_16 shikimate kinase activity K00891,K13829 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000001081 201.0
HKD1_k127_2960588_17 PFAM Fibronectin type III domain - - - 0.000000000000000000000000000000000000000006708 178.0
HKD1_k127_2960588_18 PFAM Haloacid dehalogenase domain protein hydrolase K02566 - - 0.000000000000000000000000000000000000000028 164.0
HKD1_k127_2960588_19 TPR repeat - - - 0.0000000000000000000000000000000000000002038 170.0
HKD1_k127_2960588_2 FtsX-like permease family K02004 - - 3.321e-199 648.0
HKD1_k127_2960588_20 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000008502 161.0
HKD1_k127_2960588_21 response to copper ion K07156,K14166 - - 0.00000000000000000000000000005838 133.0
HKD1_k127_2960588_22 - - - - 0.000000000000001063 88.0
HKD1_k127_2960588_3 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 545.0
HKD1_k127_2960588_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 445.0
HKD1_k127_2960588_5 ATP-grasp domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 421.0
HKD1_k127_2960588_6 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 332.0
HKD1_k127_2960588_7 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 305.0
HKD1_k127_2960588_8 lipoprotein transporter activity K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 294.0
HKD1_k127_2960588_9 Membrane protein, TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 295.0
HKD1_k127_298263_0 fad dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 452.0
HKD1_k127_298263_1 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 311.0
HKD1_k127_3014756_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 371.0
HKD1_k127_3024735_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.254e-206 659.0
HKD1_k127_3024735_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 567.0
HKD1_k127_3024735_10 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 359.0
HKD1_k127_3024735_11 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 366.0
HKD1_k127_3024735_12 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 333.0
HKD1_k127_3024735_13 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009936 314.0
HKD1_k127_3024735_14 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 300.0
HKD1_k127_3024735_15 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002031 287.0
HKD1_k127_3024735_16 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002399 265.0
HKD1_k127_3024735_17 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000005833 263.0
HKD1_k127_3024735_18 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000002138 226.0
HKD1_k127_3024735_19 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000006091 220.0
HKD1_k127_3024735_2 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 542.0
HKD1_k127_3024735_20 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000004291 138.0
HKD1_k127_3024735_21 TIGRFAM Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily - - - 0.000000000000000000000000000000009129 137.0
HKD1_k127_3024735_22 hydroperoxide reductase activity - - - 0.0000000000000000000000000000003524 123.0
HKD1_k127_3024735_23 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000001305 125.0
HKD1_k127_3024735_24 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000003067 119.0
HKD1_k127_3024735_25 response regulator - - - 0.00000000000000000000000000008398 127.0
HKD1_k127_3024735_26 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000001054 112.0
HKD1_k127_3024735_27 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000009679 106.0
HKD1_k127_3024735_28 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000002959 88.0
HKD1_k127_3024735_29 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.000007199 51.0
HKD1_k127_3024735_3 PFAM Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 543.0
HKD1_k127_3024735_30 Tripartite tricarboxylate transporter TctB family - - - 0.0002442 53.0
HKD1_k127_3024735_4 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 492.0
HKD1_k127_3024735_5 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 454.0
HKD1_k127_3024735_6 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 415.0
HKD1_k127_3024735_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 377.0
HKD1_k127_3024735_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 379.0
HKD1_k127_3024735_9 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 372.0
HKD1_k127_3028080_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 3.308e-252 792.0
HKD1_k127_3028080_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 2.643e-233 741.0
HKD1_k127_3028080_10 arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 309.0
HKD1_k127_3028080_11 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004781 286.0
HKD1_k127_3028080_12 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004721 267.0
HKD1_k127_3028080_13 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004555 274.0
HKD1_k127_3028080_14 permease - - - 0.000000000000000000000000000000000000000000000000000000000000008709 229.0
HKD1_k127_3028080_15 Short-chain dehydrogenase reductase sdr K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000005698 216.0
HKD1_k127_3028080_16 LppP/LprE lipoprotein - - - 0.00000000000000000000000000000000000000008022 165.0
HKD1_k127_3028080_17 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.000000000000000000000000000000000000006652 153.0
HKD1_k127_3028080_18 Nitrile hydratase beta subunit - - - 0.000000000000000000000000000000000001727 143.0
HKD1_k127_3028080_19 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000001066 152.0
HKD1_k127_3028080_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 599.0
HKD1_k127_3028080_20 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000001082 139.0
HKD1_k127_3028080_21 - - - - 0.000000000000000000000000000004504 123.0
HKD1_k127_3028080_22 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000001268 102.0
HKD1_k127_3028080_23 peptidyl-prolyl cis-trans isomerase activity K00645,K02597,K03769,K03771 - 2.3.1.39,5.2.1.8 0.0002156 55.0
HKD1_k127_3028080_3 PFAM Pyridine nucleotide-disulphide oxidoreductase, FAD NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008547 486.0
HKD1_k127_3028080_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 487.0
HKD1_k127_3028080_5 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 475.0
HKD1_k127_3028080_6 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 438.0
HKD1_k127_3028080_7 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 427.0
HKD1_k127_3028080_8 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 346.0
HKD1_k127_3028080_9 Nitrile hydratase, alpha chain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 332.0
HKD1_k127_3034989_0 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 507.0
HKD1_k127_3034989_1 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 446.0
HKD1_k127_3034989_2 regulatory protein, gntR - - - 0.00000000000000000000000000000000000000000000000000000000000000000007466 244.0
HKD1_k127_3034989_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000001576 138.0
HKD1_k127_3034989_4 Psort location Cytoplasmic, score - - - 0.0000000000000003618 92.0
HKD1_k127_3034989_5 Putative zinc-finger - - - 0.00000004952 66.0
HKD1_k127_3038043_0 aldehyde ferredoxin oxidoreductase activity K03738 - 1.2.7.5 6.602e-194 631.0
HKD1_k127_3038043_1 ribonuclease BN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 298.0
HKD1_k127_3038043_10 - K06039 - - 0.00000000001202 72.0
HKD1_k127_3038043_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005615 259.0
HKD1_k127_3038043_3 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000006955 238.0
HKD1_k127_3038043_4 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.00000000000000000000000000000000000000000000000000000000000000001661 237.0
HKD1_k127_3038043_5 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000002853 229.0
HKD1_k127_3038043_6 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000002128 188.0
HKD1_k127_3038043_7 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000004091 154.0
HKD1_k127_3038043_8 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000007062 124.0
HKD1_k127_3038043_9 - - - - 0.00000000000006308 79.0
HKD1_k127_3068350_0 Forkhead associated domain K07169 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 301.0
HKD1_k127_3073465_0 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 479.0
HKD1_k127_3073465_1 BFD-like [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 312.0
HKD1_k127_3073465_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 312.0
HKD1_k127_3073465_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 293.0
HKD1_k127_3073465_4 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004476 259.0
HKD1_k127_3073465_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000004576 235.0
HKD1_k127_3073465_6 Glyoxalase-like domain K07032 - - 0.0000000000000000000000000000000000000000000000000000000001019 207.0
HKD1_k127_3073465_8 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000002384 100.0
HKD1_k127_3100705_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 556.0
HKD1_k127_3100705_1 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 477.0
HKD1_k127_3100705_10 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000001634 104.0
HKD1_k127_3100705_11 Cytochrome c K00413 - - 0.00000000000000000000002869 115.0
HKD1_k127_3100705_12 PFAM Ribbon-helix-helix protein, copG family K21495 - - 0.000000000000002155 78.0
HKD1_k127_3100705_14 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000003285 72.0
HKD1_k127_3100705_2 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 348.0
HKD1_k127_3100705_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 343.0
HKD1_k127_3100705_4 4Fe-4S binding domain K08358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 334.0
HKD1_k127_3100705_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 293.0
HKD1_k127_3100705_6 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003051 295.0
HKD1_k127_3100705_7 symporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006452 256.0
HKD1_k127_3100705_8 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000000000000002504 203.0
HKD1_k127_3100705_9 Fic/DOC family K07341 - - 0.0000000000000000000000000000000000000001905 155.0
HKD1_k127_3110211_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1139.0
HKD1_k127_3110211_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.498e-224 711.0
HKD1_k127_3110211_10 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000000000000000007398 104.0
HKD1_k127_3110211_11 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000005508 102.0
HKD1_k127_3110211_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000485 68.0
HKD1_k127_3110211_13 Elongation factor SelB winged helix 3 K03833 - - 0.00000000001378 73.0
HKD1_k127_3110211_14 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179,K04090 - 1.2.7.8 0.00000001202 59.0
HKD1_k127_3110211_15 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.0002535 46.0
HKD1_k127_3110211_2 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 522.0
HKD1_k127_3110211_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 438.0
HKD1_k127_3110211_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 424.0
HKD1_k127_3110211_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005183 279.0
HKD1_k127_3110211_6 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000001033 226.0
HKD1_k127_3110211_7 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000009369 207.0
HKD1_k127_3110211_8 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000001498 155.0
HKD1_k127_3110211_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000009651 129.0
HKD1_k127_3135976_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 298.0
HKD1_k127_3135976_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 291.0
HKD1_k127_3135976_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02031,K02032,K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001817 257.0
HKD1_k127_3135976_3 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000635 193.0
HKD1_k127_3135976_4 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000006956 118.0
HKD1_k127_3135976_5 CopG domain protein DNA-binding domain protein K18918 - - 0.0000000000000001495 81.0
HKD1_k127_3135976_6 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000005403 75.0
HKD1_k127_3138788_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 6.57e-322 1024.0
HKD1_k127_3138788_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 8.836e-298 923.0
HKD1_k127_3138788_10 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000105 190.0
HKD1_k127_3138788_11 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000004996 117.0
HKD1_k127_3138788_12 response regulator K07715 - - 0.0000000002117 69.0
HKD1_k127_3138788_13 protein histidine kinase activity K07648 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000006804 61.0
HKD1_k127_3138788_14 AMP binding - - - 0.000004329 51.0
HKD1_k127_3138788_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 2.18e-198 640.0
HKD1_k127_3138788_3 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 539.0
HKD1_k127_3138788_4 Terminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 479.0
HKD1_k127_3138788_5 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 322.0
HKD1_k127_3138788_6 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 314.0
HKD1_k127_3138788_7 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000003985 265.0
HKD1_k127_3138788_8 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000002723 274.0
HKD1_k127_3138788_9 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000002949 240.0
HKD1_k127_3142253_0 Peptidase family M1 domain K08776 - - 2.594e-218 714.0
HKD1_k127_3142253_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 446.0
HKD1_k127_3142253_10 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002355 282.0
HKD1_k127_3142253_11 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000003829 243.0
HKD1_k127_3142253_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000005045 218.0
HKD1_k127_3142253_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000007711 219.0
HKD1_k127_3142253_14 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000006915 216.0
HKD1_k127_3142253_15 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000007007 206.0
HKD1_k127_3142253_16 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000009988 153.0
HKD1_k127_3142253_17 Major Facilitator Superfamily - - - 0.0000000000000000000000002392 120.0
HKD1_k127_3142253_18 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000001774 90.0
HKD1_k127_3142253_19 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000001185 87.0
HKD1_k127_3142253_2 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 394.0
HKD1_k127_3142253_20 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000000000000001436 80.0
HKD1_k127_3142253_21 SMART zinc finger CDGSH-type domain protein - - - 0.000000000001059 76.0
HKD1_k127_3142253_22 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000004515 63.0
HKD1_k127_3142253_23 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000138 49.0
HKD1_k127_3142253_3 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 361.0
HKD1_k127_3142253_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 338.0
HKD1_k127_3142253_5 PFAM amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 324.0
HKD1_k127_3142253_6 endonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 317.0
HKD1_k127_3142253_7 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 289.0
HKD1_k127_3142253_8 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002072 274.0
HKD1_k127_3142253_9 Dihydroorotase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002421 266.0
HKD1_k127_3142255_0 Glycosyltransferase, group 2 family protein K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 566.0
HKD1_k127_3142255_1 ABC transporter K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 310.0
HKD1_k127_3142255_2 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001477 250.0
HKD1_k127_3142255_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000009333 187.0
HKD1_k127_3142255_4 Transport permease protein K01992,K09690 - - 0.0000000000000000000000000000000000000000000003071 178.0
HKD1_k127_3142255_5 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000000000000000398 191.0
HKD1_k127_3142255_6 Protein of unknown function (DUF1566) - - - 0.0000000000000000000000000000000000005591 158.0
HKD1_k127_3142255_7 - - - - 0.00002989 57.0
HKD1_k127_3145841_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 363.0
HKD1_k127_3145841_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000166 76.0
HKD1_k127_3156748_0 AMP-binding enzyme C-terminal domain K20034 - 6.2.1.44 3.704e-212 672.0
HKD1_k127_3156748_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 355.0
HKD1_k127_3156748_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 345.0
HKD1_k127_3156748_3 Matrixin - - - 0.0000000000000000000000000000000000004367 152.0
HKD1_k127_3156748_4 hydroperoxide reductase activity - - - 0.000003034 53.0
HKD1_k127_3158340_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.528e-217 706.0
HKD1_k127_3158340_1 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 642.0
HKD1_k127_3158340_10 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 380.0
HKD1_k127_3158340_11 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 362.0
HKD1_k127_3158340_12 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 362.0
HKD1_k127_3158340_13 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 332.0
HKD1_k127_3158340_14 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001309 281.0
HKD1_k127_3158340_15 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004755 286.0
HKD1_k127_3158340_16 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000004824 278.0
HKD1_k127_3158340_17 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003006 260.0
HKD1_k127_3158340_18 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000003071 248.0
HKD1_k127_3158340_19 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000001093 252.0
HKD1_k127_3158340_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 552.0
HKD1_k127_3158340_20 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000047 212.0
HKD1_k127_3158340_21 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000005485 191.0
HKD1_k127_3158340_22 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000006852 176.0
HKD1_k127_3158340_23 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000001038 178.0
HKD1_k127_3158340_24 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000002192 188.0
HKD1_k127_3158340_25 histidine kinase HAMP region domain protein K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000005041 183.0
HKD1_k127_3158340_26 PFAM Phosphoglycerate mutase K02226,K22305 - 3.1.3.3,3.1.3.73 0.000000000000000000000000000000000002005 149.0
HKD1_k127_3158340_27 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000549 137.0
HKD1_k127_3158340_28 - - - - 0.0000000001437 66.0
HKD1_k127_3158340_29 HD domain - - - 0.00000002273 56.0
HKD1_k127_3158340_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 531.0
HKD1_k127_3158340_4 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 475.0
HKD1_k127_3158340_5 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 464.0
HKD1_k127_3158340_6 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 419.0
HKD1_k127_3158340_7 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 387.0
HKD1_k127_3158340_8 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 372.0
HKD1_k127_3158340_9 PFAM Na Picotransporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 377.0
HKD1_k127_3159034_0 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001248 290.0
HKD1_k127_3159034_1 Protein of unknown function (DUF2652) - - - 0.00000000000000000000000000000000007634 136.0
HKD1_k127_3159034_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000001198 75.0
HKD1_k127_3159034_3 Protein of unknown function (DUF2652) - - - 0.000003845 55.0
HKD1_k127_3166052_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 398.0
HKD1_k127_3166052_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 339.0
HKD1_k127_3170666_0 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 497.0
HKD1_k127_3170666_1 MlrC C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 428.0
HKD1_k127_3170666_2 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 374.0
HKD1_k127_3170666_3 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 342.0
HKD1_k127_3170666_4 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 321.0
HKD1_k127_3170666_5 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 299.0
HKD1_k127_3170666_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000007805 203.0
HKD1_k127_3170666_7 Cupin domain - - - 0.000000000000000000000000000000000000103 146.0
HKD1_k127_3170666_8 Protein of unknown function (DUF1054) - - - 0.000000000000000000000000000000258 131.0
HKD1_k127_3172962_0 FAD dependent oxidoreductase - - - 0.0 1077.0
HKD1_k127_3172962_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 2.823e-277 861.0
HKD1_k127_3172962_2 PIN domain - - - 0.0000000000000000000000000000000000000000000000000001139 189.0
HKD1_k127_3172962_3 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000000000487 173.0
HKD1_k127_3172962_4 SpoVT AbrB like domain - - - 0.000000000000000004556 85.0
HKD1_k127_3181319_0 COG1960 Acyl-CoA dehydrogenases - - - 3.995e-208 653.0
HKD1_k127_3181319_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 545.0
HKD1_k127_3181319_2 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 492.0
HKD1_k127_3181319_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 405.0
HKD1_k127_3181319_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 394.0
HKD1_k127_3181319_5 branched-chain amino acid K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 351.0
HKD1_k127_3181319_6 amino acid K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 313.0
HKD1_k127_3181319_7 Protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000002523 121.0
HKD1_k127_318602_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.309e-284 894.0
HKD1_k127_318602_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.439e-212 677.0
HKD1_k127_318602_10 COGs COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 467.0
HKD1_k127_318602_11 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 390.0
HKD1_k127_318602_12 NAD binding K03778 - 1.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 326.0
HKD1_k127_318602_13 TIGRFAM geranylgeranyl reductase K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 301.0
HKD1_k127_318602_14 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002005 277.0
HKD1_k127_318602_15 Binding-protein-dependent transport system inner membrane component K02025,K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005374 263.0
HKD1_k127_318602_16 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004312 265.0
HKD1_k127_318602_17 AMP-binding enzyme C-terminal domain K01897,K18661 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000001107 274.0
HKD1_k127_318602_18 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005655 254.0
HKD1_k127_318602_19 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000008361 243.0
HKD1_k127_318602_2 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 600.0
HKD1_k127_318602_20 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000005439 240.0
HKD1_k127_318602_21 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000001459 229.0
HKD1_k127_318602_22 cobalamin binding K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000209 221.0
HKD1_k127_318602_23 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000001701 234.0
HKD1_k127_318602_24 PFAM Bacterial transferase hexapeptide (three repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000006313 218.0
HKD1_k127_318602_25 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000259 214.0
HKD1_k127_318602_26 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000004259 169.0
HKD1_k127_318602_27 Bacterial transferase hexapeptide (six repeats) K02536 - 2.3.1.191 0.000000000000000000000000000000000000000001475 175.0
HKD1_k127_318602_28 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000001807 147.0
HKD1_k127_318602_29 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000000000002014 148.0
HKD1_k127_318602_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 587.0
HKD1_k127_318602_30 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000002526 147.0
HKD1_k127_318602_31 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000004395 142.0
HKD1_k127_318602_32 Thioesterase superfamily - - - 0.000000000000000000000000000000008363 140.0
HKD1_k127_318602_33 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.0000000000000000000000000000003652 130.0
HKD1_k127_318602_34 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000009532 131.0
HKD1_k127_318602_35 Thioesterase superfamily - - - 0.00000000000000000000000000006007 125.0
HKD1_k127_318602_36 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000002397 116.0
HKD1_k127_318602_37 - - - - 0.0000000000000000000000001328 116.0
HKD1_k127_318602_38 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.00000000000000000000006874 112.0
HKD1_k127_318602_39 - - - - 0.0000000000000000000001027 106.0
HKD1_k127_318602_4 COGs COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 550.0
HKD1_k127_318602_40 methionine synthase - - - 0.00000000000000001415 92.0
HKD1_k127_318602_41 extracellular solute-binding protein, family 1 K17244 - - 0.0000000001836 74.0
HKD1_k127_318602_42 Hexapeptide repeat of succinyl-transferase - - - 0.00000004051 63.0
HKD1_k127_318602_43 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000004259 66.0
HKD1_k127_318602_44 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000007086 54.0
HKD1_k127_318602_5 Psort location CytoplasmicMembrane, score 10.00 K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 509.0
HKD1_k127_318602_6 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 496.0
HKD1_k127_318602_7 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 498.0
HKD1_k127_318602_8 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 479.0
HKD1_k127_318602_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 477.0
HKD1_k127_3220756_0 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 325.0
HKD1_k127_3220756_1 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000001138 175.0
HKD1_k127_3220756_2 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000008806 138.0
HKD1_k127_3220756_3 Function of homologous gene experimentally demonstrated in an other organism K06015 - 3.5.1.81 0.00000000000000000000000000000000412 138.0
HKD1_k127_3239677_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 487.0
HKD1_k127_3239677_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 378.0
HKD1_k127_3239677_10 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000009638 204.0
HKD1_k127_3239677_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043021,GO:0043022,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000002733 166.0
HKD1_k127_3239677_12 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000458 157.0
HKD1_k127_3239677_13 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.000000000000000000000000000003695 127.0
HKD1_k127_3239677_14 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000003515 106.0
HKD1_k127_3239677_15 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000003312 104.0
HKD1_k127_3239677_16 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000000000005236 103.0
HKD1_k127_3239677_17 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00006939 52.0
HKD1_k127_3239677_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 344.0
HKD1_k127_3239677_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 292.0
HKD1_k127_3239677_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 291.0
HKD1_k127_3239677_5 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000007656 263.0
HKD1_k127_3239677_6 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000435 247.0
HKD1_k127_3239677_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000004239 235.0
HKD1_k127_3239677_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000002888 220.0
HKD1_k127_3239677_9 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000001749 198.0
HKD1_k127_3243337_0 PFAM luciferase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 347.0
HKD1_k127_3243337_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000002511 210.0
HKD1_k127_3243337_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000162 186.0
HKD1_k127_3255832_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 3.439e-197 638.0
HKD1_k127_3255832_1 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 569.0
HKD1_k127_3255832_10 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 458.0
HKD1_k127_3255832_11 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 432.0
HKD1_k127_3255832_12 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 334.0
HKD1_k127_3255832_13 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 334.0
HKD1_k127_3255832_14 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 322.0
HKD1_k127_3255832_15 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 320.0
HKD1_k127_3255832_16 NADH dehydrogenase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 312.0
HKD1_k127_3255832_17 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 301.0
HKD1_k127_3255832_18 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009416 277.0
HKD1_k127_3255832_19 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002182 274.0
HKD1_k127_3255832_2 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 538.0
HKD1_k127_3255832_20 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002035 252.0
HKD1_k127_3255832_21 mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.000000000000000000000000000000000000000000000000000000000000000000009605 246.0
HKD1_k127_3255832_22 photosynthesis - - - 0.00000000000000000000000000000000000000000000000000002684 192.0
HKD1_k127_3255832_23 cheY-homologous receiver domain K11443 - - 0.0000000000000000000000000000000000000000000001081 182.0
HKD1_k127_3255832_24 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000005788 181.0
HKD1_k127_3255832_25 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000003089 170.0
HKD1_k127_3255832_26 nitric oxide dioxygenase activity - - - 0.00000000000000000000000000000000000000546 150.0
HKD1_k127_3255832_27 - - - - 0.000000000000000000000000000000000007069 141.0
HKD1_k127_3255832_28 PIN domain - - - 0.0000000000000000000000000000000002432 146.0
HKD1_k127_3255832_29 phosphorelay signal transduction system K11443 - - 0.0000000000000000000000000000001084 142.0
HKD1_k127_3255832_3 Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 542.0
HKD1_k127_3255832_30 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000634 108.0
HKD1_k127_3255832_31 Histidine kinase-like ATPase domain - - - 0.00000000000000000000002574 110.0
HKD1_k127_3255832_32 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000000006238 94.0
HKD1_k127_3255832_33 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.00000000000000000005406 100.0
HKD1_k127_3255832_34 CoA-transferase family III K07749 - 2.8.3.16 0.00000003729 57.0
HKD1_k127_3255832_4 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 555.0
HKD1_k127_3255832_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 546.0
HKD1_k127_3255832_6 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 497.0
HKD1_k127_3255832_7 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 499.0
HKD1_k127_3255832_8 PFAM FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 505.0
HKD1_k127_3255832_9 FMN-dependent dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 458.0
HKD1_k127_3267156_0 Adenylate and Guanylate cyclase catalytic domain - - - 3.234e-271 873.0
HKD1_k127_3267156_1 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 530.0
HKD1_k127_3267156_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 302.0
HKD1_k127_3267156_11 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 302.0
HKD1_k127_3267156_12 fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 295.0
HKD1_k127_3267156_13 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000001166 244.0
HKD1_k127_3267156_15 - - - - 0.000000000000000000000000000000000000000000000000000000002638 219.0
HKD1_k127_3267156_16 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000003358 194.0
HKD1_k127_3267156_17 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000003173 177.0
HKD1_k127_3267156_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000008462 153.0
HKD1_k127_3267156_19 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000004244 152.0
HKD1_k127_3267156_2 Bacterial sugar transferase K03606,K20997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 503.0
HKD1_k127_3267156_20 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000006413 139.0
HKD1_k127_3267156_21 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000002973 124.0
HKD1_k127_3267156_22 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000001354 122.0
HKD1_k127_3267156_23 - - - - 0.0000000000000000000000001971 120.0
HKD1_k127_3267156_24 Sulfotransferase family - - - 0.000000000000000000000005973 119.0
HKD1_k127_3267156_25 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000004458 105.0
HKD1_k127_3267156_26 O-Antigen ligase K18814 - - 0.00000000000000004855 94.0
HKD1_k127_3267156_27 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000007304 77.0
HKD1_k127_3267156_28 Alpha/beta hydrolase family - - - 0.00000000001505 67.0
HKD1_k127_3267156_29 COG1555 DNA uptake protein and related DNA-binding K02237 - - 0.0000000001243 70.0
HKD1_k127_3267156_3 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 467.0
HKD1_k127_3267156_30 PBS lyase HEAT-like repeat - - - 0.0000000007759 72.0
HKD1_k127_3267156_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 441.0
HKD1_k127_3267156_5 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 429.0
HKD1_k127_3267156_6 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 389.0
HKD1_k127_3267156_7 Metallo-beta-lactamase superfamily K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 369.0
HKD1_k127_3267156_8 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 347.0
HKD1_k127_3267156_9 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 322.0
HKD1_k127_3268303_0 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 447.0
HKD1_k127_3287492_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 8.585e-269 852.0
HKD1_k127_3287492_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.963e-222 736.0
HKD1_k127_3287492_10 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 298.0
HKD1_k127_3287492_11 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 299.0
HKD1_k127_3287492_12 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 298.0
HKD1_k127_3287492_13 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003029 271.0
HKD1_k127_3287492_14 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001884 269.0
HKD1_k127_3287492_15 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002134 246.0
HKD1_k127_3287492_16 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000001799 238.0
HKD1_k127_3287492_17 Belongs to the short-chain dehydrogenases reductases (SDR) family K03366 - 1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000008851 213.0
HKD1_k127_3287492_18 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000002704 215.0
HKD1_k127_3287492_19 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000003145 192.0
HKD1_k127_3287492_2 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 488.0
HKD1_k127_3287492_20 NAD(P)-binding Rossmann-like domain K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000003596 192.0
HKD1_k127_3287492_21 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000000000003178 175.0
HKD1_k127_3287492_22 Domain of unknown function (DUF697) K08990 - - 0.0000000000000000000000000000000002169 146.0
HKD1_k127_3287492_23 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000007927 125.0
HKD1_k127_3287492_24 Conserved hypothetical protein (Lin0512_fam) - - - 0.0000000000000000002839 102.0
HKD1_k127_3287492_25 - - - - 0.0000000000000000002874 93.0
HKD1_k127_3287492_26 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000002255 68.0
HKD1_k127_3287492_28 Beta-lactamase - - - 0.0000002265 54.0
HKD1_k127_3287492_3 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 486.0
HKD1_k127_3287492_4 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 476.0
HKD1_k127_3287492_5 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 450.0
HKD1_k127_3287492_6 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 443.0
HKD1_k127_3287492_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 379.0
HKD1_k127_3287492_8 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 356.0
HKD1_k127_3287492_9 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 323.0
HKD1_k127_330685_0 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 494.0
HKD1_k127_330685_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 394.0
HKD1_k127_330685_2 Flagellar Assembly Protein A K09749 - - 0.00000000000000000000000000000000000000000000000000000000000002712 229.0
HKD1_k127_330685_3 coenzyme F390 K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000251 203.0
HKD1_k127_330685_4 carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000000001839 173.0
HKD1_k127_330685_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000003736 158.0
HKD1_k127_330685_6 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000001332 153.0
HKD1_k127_3319915_0 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 429.0
HKD1_k127_3319915_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 408.0
HKD1_k127_3319915_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 383.0
HKD1_k127_3319915_3 protein histidine kinase activity K07315,K07641,K10819,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 320.0
HKD1_k127_3319915_4 glycolate biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 301.0
HKD1_k127_3319915_5 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001421 284.0
HKD1_k127_3319915_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001089 258.0
HKD1_k127_3319915_7 PIN domain - - - 0.0000000000000000000000000000000000001475 145.0
HKD1_k127_3319915_8 - K21495 - - 0.000000005269 61.0
HKD1_k127_3382085_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1723.0
HKD1_k127_3382085_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01535,K12955 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2,3.6.3.6 0.0 1061.0
HKD1_k127_3382085_10 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.354e-204 643.0
HKD1_k127_3382085_11 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 2.716e-201 648.0
HKD1_k127_3382085_12 Cytochrome C and Quinol oxidase polypeptide I - - - 4.221e-199 634.0
HKD1_k127_3382085_13 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 538.0
HKD1_k127_3382085_14 MacB-like periplasmic core domain K02004,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 493.0
HKD1_k127_3382085_15 Transketolase, C-terminal domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 473.0
HKD1_k127_3382085_16 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 456.0
HKD1_k127_3382085_17 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 444.0
HKD1_k127_3382085_18 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 435.0
HKD1_k127_3382085_19 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 420.0
HKD1_k127_3382085_2 Belongs to the IlvD Edd family K22396 - 4.2.1.82 4.065e-320 993.0
HKD1_k127_3382085_20 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 423.0
HKD1_k127_3382085_21 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 419.0
HKD1_k127_3382085_22 Radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 412.0
HKD1_k127_3382085_23 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 387.0
HKD1_k127_3382085_24 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 363.0
HKD1_k127_3382085_25 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 338.0
HKD1_k127_3382085_26 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 340.0
HKD1_k127_3382085_27 phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 341.0
HKD1_k127_3382085_28 Helix-hairpin-helix domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 327.0
HKD1_k127_3382085_29 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 326.0
HKD1_k127_3382085_3 Heat shock 70 kDa protein K04043 - - 1.764e-304 944.0
HKD1_k127_3382085_30 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 306.0
HKD1_k127_3382085_31 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 295.0
HKD1_k127_3382085_32 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 302.0
HKD1_k127_3382085_33 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003343 288.0
HKD1_k127_3382085_34 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001185 278.0
HKD1_k127_3382085_35 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000001416 249.0
HKD1_k127_3382085_36 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000003363 248.0
HKD1_k127_3382085_37 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000006318 227.0
HKD1_k127_3382085_38 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000002452 221.0
HKD1_k127_3382085_39 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000001108 222.0
HKD1_k127_3382085_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.407e-288 895.0
HKD1_k127_3382085_40 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000000000000232 194.0
HKD1_k127_3382085_41 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000006884 199.0
HKD1_k127_3382085_42 - - - - 0.00000000000000000000000000000000000000000000000006302 188.0
HKD1_k127_3382085_43 translation release factor activity K03265 - - 0.00000000000000000000000000000000000000000000001255 185.0
HKD1_k127_3382085_44 - - - - 0.0000000000000000000000000000000000000000000001036 173.0
HKD1_k127_3382085_45 - - - - 0.0000000000000000000000000000000000000000000001568 179.0
HKD1_k127_3382085_46 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000003108 176.0
HKD1_k127_3382085_47 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000007721 188.0
HKD1_k127_3382085_48 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000004115 164.0
HKD1_k127_3382085_49 conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000000000001372 167.0
HKD1_k127_3382085_5 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 9.404e-261 828.0
HKD1_k127_3382085_50 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000003413 148.0
HKD1_k127_3382085_51 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00000000000000000000000000000000000004226 150.0
HKD1_k127_3382085_52 ATP-independent chaperone mediated protein folding - - - 0.00000000000000000000000000000000000009597 149.0
HKD1_k127_3382085_53 Domain in cystathionine beta-synthase and other proteins. K04767 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.0000000000000000000000000000000000001372 161.0
HKD1_k127_3382085_54 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.00000000000000000000000000000000009111 143.0
HKD1_k127_3382085_55 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503 - - 0.00000000000000000000000000000003097 130.0
HKD1_k127_3382085_56 GYD domain - - - 0.0000000000000000000000000000000582 131.0
HKD1_k127_3382085_57 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000001588 128.0
HKD1_k127_3382085_58 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000004932 131.0
HKD1_k127_3382085_59 - - - - 0.000000000000000000000000008575 115.0
HKD1_k127_3382085_6 Phosphate acyltransferases K01897 - 6.2.1.3 1.339e-260 832.0
HKD1_k127_3382085_60 Universal stress protein - - - 0.0000000000000000000000000884 113.0
HKD1_k127_3382085_61 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.000000000000000000000000229 112.0
HKD1_k127_3382085_62 Cbs domain K04767 - - 0.0000000000000000000000008817 109.0
HKD1_k127_3382085_63 Universal stress protein family - - - 0.00000000000000000000002699 110.0
HKD1_k127_3382085_64 PFAM CBS domain containing protein K04767 - - 0.000000000000000000001248 102.0
HKD1_k127_3382085_65 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000003298 99.0
HKD1_k127_3382085_66 Universal stress protein - - - 0.0000000000000000000341 98.0
HKD1_k127_3382085_67 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000003702 98.0
HKD1_k127_3382085_68 Cbs domain K04767 - - 0.00000000000000002238 87.0
HKD1_k127_3382085_69 Muconolactone delta-isomerase K03464 - 5.3.3.4 0.00000000000000002689 87.0
HKD1_k127_3382085_7 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 2.456e-242 808.0
HKD1_k127_3382085_70 CBS domain K04767 - - 0.00000000000000003286 88.0
HKD1_k127_3382085_71 Phosphopantetheine attachment site - - - 0.0000000000000002414 92.0
HKD1_k127_3382085_72 Uncharacterized conserved protein (DUF2267) - - - 0.000000000000004619 87.0
HKD1_k127_3382085_73 Alpha/beta hydrolase family - - - 0.00000000000006953 84.0
HKD1_k127_3382085_74 Universal stress protein family - - - 0.000000000000256 76.0
HKD1_k127_3382085_75 - - - - 0.0000000000009156 80.0
HKD1_k127_3382085_76 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000009922 73.0
HKD1_k127_3382085_77 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000001044 73.0
HKD1_k127_3382085_78 Belongs to the universal stress protein A family - - - 0.000000001591 69.0
HKD1_k127_3382085_79 - - - - 0.00000002838 57.0
HKD1_k127_3382085_8 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 7.184e-241 758.0
HKD1_k127_3382085_80 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000005186 58.0
HKD1_k127_3382085_81 Uncharacterized conserved protein (DUF2267) - - - 0.00000008848 59.0
HKD1_k127_3382085_82 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000004597 58.0
HKD1_k127_3382085_83 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.00001273 54.0
HKD1_k127_3382085_84 Muconolactone delta-isomerase K03464 - 5.3.3.4 0.00001565 51.0
HKD1_k127_3382085_9 Belongs to the peptidase S16 family K04076 - 3.4.21.53 3.768e-219 704.0
HKD1_k127_3384835_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.736e-239 751.0
HKD1_k127_3384835_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 570.0
HKD1_k127_3384835_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 322.0
HKD1_k127_3384835_3 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000001822 259.0
HKD1_k127_3384835_4 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000002353 229.0
HKD1_k127_3384835_5 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001214 229.0
HKD1_k127_3384835_6 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.0000000000000000000000000000000000000003289 154.0
HKD1_k127_3384835_7 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000001353 161.0
HKD1_k127_3384835_8 Phosphate acyltransferases - - - 0.00004963 53.0
HKD1_k127_3459024_0 PFAM multi antimicrobial extrusion protein MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 433.0
HKD1_k127_3459024_1 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 346.0
HKD1_k127_3459024_2 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000002651 221.0
HKD1_k127_3459024_3 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000000000000000007772 206.0
HKD1_k127_3459024_4 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000001072 196.0
HKD1_k127_3459024_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000000000000000242 196.0
HKD1_k127_3459024_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.000000000006533 72.0
HKD1_k127_3459024_7 PIN domain K07065 - - 0.0000000007049 66.0
HKD1_k127_3459024_8 Poly A polymerase head domain K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.00001718 57.0
HKD1_k127_3471967_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000005991 248.0
HKD1_k127_3482242_0 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.0 1101.0
HKD1_k127_3482242_1 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 579.0
HKD1_k127_3482242_10 PFAM CBS domain K04767 - - 0.000000000000000000000000000000000000000001436 160.0
HKD1_k127_3482242_11 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000001872 173.0
HKD1_k127_3482242_12 PFAM UspA domain protein - - - 0.00000000000000000000000002318 116.0
HKD1_k127_3482242_13 Sulphur transport K07112 - - 0.0000000000000000000005242 99.0
HKD1_k127_3482242_14 FixH - - - 0.000000000000000000001866 100.0
HKD1_k127_3482242_15 Belongs to the universal stress protein A family - - - 0.00000000000000000001228 99.0
HKD1_k127_3482242_16 Sulphur transport K07112 - - 0.0000000000000000000232 102.0
HKD1_k127_3482242_17 - K07112 - - 0.00000000000000000004505 91.0
HKD1_k127_3482242_18 Universal stress protein K06149 - - 0.00000000000000000007613 97.0
HKD1_k127_3482242_19 Universal stress protein - - - 0.00000000000000002743 92.0
HKD1_k127_3482242_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 520.0
HKD1_k127_3482242_20 Two component, sigma54 specific transcriptional regulator, fis family K10912 - - 0.0000000002908 70.0
HKD1_k127_3482242_21 Sulphur transport K07112 - - 0.00000001262 56.0
HKD1_k127_3482242_22 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.0002865 53.0
HKD1_k127_3482242_3 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 480.0
HKD1_k127_3482242_4 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 355.0
HKD1_k127_3482242_5 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 325.0
HKD1_k127_3482242_6 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003321 250.0
HKD1_k127_3482242_7 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000001696 195.0
HKD1_k127_3482242_8 PFAM Cytochrome c, class I K00406 - - 0.0000000000000000000000000000000000000000000000002553 185.0
HKD1_k127_3482242_9 Adenylylsulphate kinase K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000008539 174.0
HKD1_k127_349610_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 529.0
HKD1_k127_349610_1 histidine kinase, HAMP K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 531.0
HKD1_k127_349610_10 CoA-ligase K02381 - - 0.00000167 61.0
HKD1_k127_349610_11 Domain of unknown function (DUF4390) - - - 0.00004881 53.0
HKD1_k127_349610_2 Protein of unknown function (DUF1116) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 484.0
HKD1_k127_349610_3 amino acid K01999,K11954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 450.0
HKD1_k127_349610_4 Succinyl-CoA synthetase, alpha subunit K02381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 379.0
HKD1_k127_349610_5 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 387.0
HKD1_k127_349610_6 Amidohydrolase family K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 365.0
HKD1_k127_349610_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002753 263.0
HKD1_k127_349610_8 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000286 251.0
HKD1_k127_349610_9 Protein of unknown function (DUF2877) - - - 0.0000000007033 72.0
HKD1_k127_3500972_0 Molybdopterin oxidoreductase Fe4S4 domain K02567 - - 0.0 1313.0
HKD1_k127_3500972_1 Adenylate and Guanylate cyclase catalytic domain - - - 9.23e-309 983.0
HKD1_k127_3500972_10 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 391.0
HKD1_k127_3500972_11 NAD dependent epimerase/dehydratase family K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 376.0
HKD1_k127_3500972_12 gluconolactonase K01053,K14274 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 368.0
HKD1_k127_3500972_13 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 360.0
HKD1_k127_3500972_14 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 333.0
HKD1_k127_3500972_15 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 321.0
HKD1_k127_3500972_16 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 302.0
HKD1_k127_3500972_17 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 298.0
HKD1_k127_3500972_18 COG4177 ABC-type branched-chain amino acid transport system, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000491 297.0
HKD1_k127_3500972_19 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002025 277.0
HKD1_k127_3500972_2 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 1.58e-271 846.0
HKD1_k127_3500972_20 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002109 260.0
HKD1_k127_3500972_21 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003215 282.0
HKD1_k127_3500972_22 Oxidoreductase activity. It is involved in the biological process described with metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001606 257.0
HKD1_k127_3500972_23 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005762 258.0
HKD1_k127_3500972_24 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002016 256.0
HKD1_k127_3500972_25 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000001019 233.0
HKD1_k127_3500972_26 - K14340 - - 0.00000000000000000000000000000000000000000000000000000000000002528 238.0
HKD1_k127_3500972_27 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000007865 181.0
HKD1_k127_3500972_28 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000005572 184.0
HKD1_k127_3500972_29 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000000000003569 172.0
HKD1_k127_3500972_3 Thiamine pyrophosphate enzyme, central domain - - - 4.135e-242 760.0
HKD1_k127_3500972_30 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000004813 147.0
HKD1_k127_3500972_31 polysaccharide deacetylase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016810,GO:0016814,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000003506 149.0
HKD1_k127_3500972_32 - - - - 0.000000000000000000000000000000001735 143.0
HKD1_k127_3500972_33 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000004619 139.0
HKD1_k127_3500972_35 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000001329 87.0
HKD1_k127_3500972_36 anaerobic respiration K02568 GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0044237,GO:0045333,GO:0055114 - 0.0000000000000007972 87.0
HKD1_k127_3500972_37 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000001595 85.0
HKD1_k127_3500972_38 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.000000000000005409 81.0
HKD1_k127_3500972_39 - - - - 0.00000000000003303 75.0
HKD1_k127_3500972_4 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 587.0
HKD1_k127_3500972_40 Cytidylate kinase-like family - - - 0.00000000000006868 81.0
HKD1_k127_3500972_41 - - - - 0.00000000001591 71.0
HKD1_k127_3500972_42 polysaccharide biosynthetic process - - - 0.000000005474 69.0
HKD1_k127_3500972_43 Flavin containing amine oxidoreductase - - - 0.00007011 54.0
HKD1_k127_3500972_5 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 526.0
HKD1_k127_3500972_6 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 500.0
HKD1_k127_3500972_7 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 494.0
HKD1_k127_3500972_8 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 469.0
HKD1_k127_3500972_9 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 469.0
HKD1_k127_3505138_0 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 328.0
HKD1_k127_3505138_1 transmembrane transport K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002472 286.0
HKD1_k127_3505138_10 Las17-binding protein actin regulator - - - 0.00000000001582 67.0
HKD1_k127_3505138_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000001317 228.0
HKD1_k127_3505138_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000003027 227.0
HKD1_k127_3505138_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000002184 229.0
HKD1_k127_3505138_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000004157 188.0
HKD1_k127_3505138_6 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000001743 188.0
HKD1_k127_3505138_7 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000004068 111.0
HKD1_k127_3505138_8 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000002505 98.0
HKD1_k127_3505138_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.0000000000000003255 84.0
HKD1_k127_3557324_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 326.0
HKD1_k127_3557324_1 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000001789 155.0
HKD1_k127_3557324_2 Trypsin K04771 - 3.4.21.107 0.000000000000003028 86.0
HKD1_k127_3576856_0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009823 436.0
HKD1_k127_3576856_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 384.0
HKD1_k127_3576856_2 TIGRFAM stage V sporulation protein E, cell division protein FtsW K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 301.0
HKD1_k127_3576856_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000006323 55.0
HKD1_k127_3580548_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 3.495e-285 892.0
HKD1_k127_3580548_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 524.0
HKD1_k127_3580548_10 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002823 284.0
HKD1_k127_3580548_11 Domain of unknown function (DUF3473) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009963 254.0
HKD1_k127_3580548_12 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004473 239.0
HKD1_k127_3580548_13 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000004464 256.0
HKD1_k127_3580548_14 sequence-specific DNA binding K00567,K13529,K15051 - 2.1.1.63,3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000003876 236.0
HKD1_k127_3580548_15 GDP-mannose 4,6 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000003937 219.0
HKD1_k127_3580548_16 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000000000000000000000000000000000000003942 186.0
HKD1_k127_3580548_17 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000003249 179.0
HKD1_k127_3580548_18 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000002876 173.0
HKD1_k127_3580548_19 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000003848 170.0
HKD1_k127_3580548_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 518.0
HKD1_k127_3580548_20 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000004291 158.0
HKD1_k127_3580548_21 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000007938 158.0
HKD1_k127_3580548_22 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000008923 132.0
HKD1_k127_3580548_23 Cytidylate kinase-like family - - - 0.00000000000000000000000000001484 129.0
HKD1_k127_3580548_24 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000001563 120.0
HKD1_k127_3580548_25 ABC transporter substrate binding protein K01989 - - 0.0000000000000000002 94.0
HKD1_k127_3580548_26 - - - - 0.000000000000000000989 89.0
HKD1_k127_3580548_27 - - - - 0.000000000001636 70.0
HKD1_k127_3580548_28 EamA-like transporter family K15268 - - 0.00000000007071 74.0
HKD1_k127_3580548_29 nucleic-acid-binding protein contains PIN domain - - - 0.000003798 58.0
HKD1_k127_3580548_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 478.0
HKD1_k127_3580548_30 - - - - 0.000005329 58.0
HKD1_k127_3580548_31 Methyltransferase - - - 0.0005021 53.0
HKD1_k127_3580548_4 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 479.0
HKD1_k127_3580548_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 440.0
HKD1_k127_3580548_6 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 385.0
HKD1_k127_3580548_7 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 369.0
HKD1_k127_3580548_8 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 357.0
HKD1_k127_3580548_9 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 358.0
HKD1_k127_3587972_0 Cytochrome c K15864 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1,1.7.99.1 4.336e-261 817.0
HKD1_k127_3587972_1 UbiA prenyltransferase family K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000002668 225.0
HKD1_k127_3587972_2 PFAM Radical SAM K22226 - - 0.0000000000000000000000000000000000000000000000000000945 192.0
HKD1_k127_3587972_3 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00000000003746 66.0
HKD1_k127_3634889_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 512.0
HKD1_k127_3634889_1 AMP-binding enzyme C-terminal domain K16876 - 6.2.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 515.0
HKD1_k127_3634889_10 Endoribonuclease L-PSP - - - 0.000000000000000000000000000008164 127.0
HKD1_k127_3634889_11 Carboxymuconolactone decarboxylase family - - - 0.000000004276 61.0
HKD1_k127_3634889_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000002635 58.0
HKD1_k127_3634889_2 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 506.0
HKD1_k127_3634889_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 503.0
HKD1_k127_3634889_4 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 416.0
HKD1_k127_3634889_5 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 374.0
HKD1_k127_3634889_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000129 211.0
HKD1_k127_3634889_7 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000007014 200.0
HKD1_k127_3634889_8 Dihydropyrimidinase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000001187 201.0
HKD1_k127_3634889_9 Tripartite ATP-independent Periplasmic Transporter - - - 0.0000000000000000000000000000000000000000003466 168.0
HKD1_k127_3652699_0 PFAM Cytochrome b b6 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 398.0
HKD1_k127_3652699_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000007833 164.0
HKD1_k127_3652699_2 oxidoreductase activity, acting on diphenols and related substances as donors K02636 - 1.10.9.1 0.000000000000000000000000000000000000006344 153.0
HKD1_k127_3652699_3 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000003845 56.0
HKD1_k127_3662244_0 Belongs to the aldehyde dehydrogenase family K21802 - 1.2.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 481.0
HKD1_k127_3662244_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 316.0
HKD1_k127_3662244_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006914 299.0
HKD1_k127_3662244_3 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005206 272.0
HKD1_k127_3662244_4 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000005019 163.0
HKD1_k127_3662244_5 - - - - 0.000000000000000000003111 104.0
HKD1_k127_3662244_6 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00001734 49.0
HKD1_k127_3662244_7 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.00002792 49.0
HKD1_k127_3665442_0 regulation of DNA-templated transcription, elongation - - - 1.121e-259 827.0
HKD1_k127_3665442_1 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 604.0
HKD1_k127_3665442_2 - - - - 0.000000000000000000000000000000000000000000000000004924 190.0
HKD1_k127_3665442_3 - - - - 0.000000000000000000000000000000000000000000000008329 176.0
HKD1_k127_3673110_0 MlaD protein K06192 - - 2.003e-218 692.0
HKD1_k127_3673110_1 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 315.0
HKD1_k127_3673110_2 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004283 251.0
HKD1_k127_3741847_0 acyl-CoA dehydrogenase K00248 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 404.0
HKD1_k127_3741847_1 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 359.0
HKD1_k127_3741847_2 COG0559 Branched-chain amino acid ABC-type transport system, permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002224 265.0
HKD1_k127_3741847_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000001367 237.0
HKD1_k127_3741847_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000001421 210.0
HKD1_k127_3741847_5 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000004807 107.0
HKD1_k127_3741847_6 Hydrolase K20862 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0022611,GO:0032502,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104 0.00000009573 56.0
HKD1_k127_3747804_0 COG5016 Pyruvate oxaloacetate carboxyltransferase K01960 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 562.0
HKD1_k127_3747804_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 531.0
HKD1_k127_3747804_10 Enoyl-(Acyl carrier protein) reductase K13774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 327.0
HKD1_k127_3747804_11 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 308.0
HKD1_k127_3747804_12 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 292.0
HKD1_k127_3747804_13 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007195 297.0
HKD1_k127_3747804_14 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000495 268.0
HKD1_k127_3747804_15 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001626 259.0
HKD1_k127_3747804_16 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001748 256.0
HKD1_k127_3747804_17 serine-type endopeptidase activity K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003359 253.0
HKD1_k127_3747804_18 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000005256 248.0
HKD1_k127_3747804_19 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000006339 248.0
HKD1_k127_3747804_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 487.0
HKD1_k127_3747804_20 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004887 241.0
HKD1_k127_3747804_21 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01535,K12955 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2,3.6.3.6 0.0000000000000000000000000000000000000000000000000000000000000005025 224.0
HKD1_k127_3747804_22 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000001774 231.0
HKD1_k127_3747804_23 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000006481 219.0
HKD1_k127_3747804_24 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000004878 214.0
HKD1_k127_3747804_25 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001332 218.0
HKD1_k127_3747804_26 light absorption - - - 0.000000000000000000000000000000000000000000000000000002936 195.0
HKD1_k127_3747804_27 - - - - 0.000000000000000000000000000000000000000000000000002339 187.0
HKD1_k127_3747804_28 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000004667 183.0
HKD1_k127_3747804_29 MaoC like domain - - - 0.00000000000000000000000000000000000000000000001943 176.0
HKD1_k127_3747804_3 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 477.0
HKD1_k127_3747804_31 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000002775 174.0
HKD1_k127_3747804_32 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000002356 154.0
HKD1_k127_3747804_33 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000114 138.0
HKD1_k127_3747804_34 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000001149 136.0
HKD1_k127_3747804_35 SNARE associated Golgi protein - - - 0.00000000000000000000000000002341 125.0
HKD1_k127_3747804_36 Putative zinc-finger - - - 0.0000000000000000000000000004885 128.0
HKD1_k127_3747804_37 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000002462 119.0
HKD1_k127_3747804_38 Histidine kinase - - - 0.000000000000000000000006148 111.0
HKD1_k127_3747804_39 - - - - 0.00000000000000000000001433 102.0
HKD1_k127_3747804_4 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 425.0
HKD1_k127_3747804_40 PFAM Excinuclease ABC, C subunit domain protein K07461 - - 0.0000000000000000000002067 100.0
HKD1_k127_3747804_41 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000001203 90.0
HKD1_k127_3747804_42 - - - - 0.00000000000000003842 96.0
HKD1_k127_3747804_43 - - - - 0.00000000004141 74.0
HKD1_k127_3747804_44 Mycolic acid cyclopropane synthetase - - - 0.0000000001947 72.0
HKD1_k127_3747804_45 Thioredoxin - - - 0.000000001329 67.0
HKD1_k127_3747804_46 cell wall anchor domain - - - 0.00001039 56.0
HKD1_k127_3747804_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 413.0
HKD1_k127_3747804_6 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 389.0
HKD1_k127_3747804_7 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 391.0
HKD1_k127_3747804_8 (ABC) transporter, permease K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 347.0
HKD1_k127_3747804_9 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 339.0
HKD1_k127_3756264_0 proline dipeptidase activity - - - 1.167e-202 638.0
HKD1_k127_3756264_1 Belongs to the class-II DAHP synthase family K01626,K16019 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0022607,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 611.0
HKD1_k127_3756264_10 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007842 265.0
HKD1_k127_3756264_11 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000002122 253.0
HKD1_k127_3756264_12 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000001088 240.0
HKD1_k127_3756264_13 ABC transporter substrate-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000002376 228.0
HKD1_k127_3756264_14 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000003294 225.0
HKD1_k127_3756264_15 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000009219 211.0
HKD1_k127_3756264_16 Binding-protein-dependent transport system inner membrane component K11078 - - 0.000000000000000000000000000000000000000000000000000003771 211.0
HKD1_k127_3756264_17 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.00000000000000000000000000000000000000000000000006374 189.0
HKD1_k127_3756264_18 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000001472 171.0
HKD1_k127_3756264_19 - - - - 0.0000000000000000000000000000000000000001485 169.0
HKD1_k127_3756264_2 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 598.0
HKD1_k127_3756264_20 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000006445 155.0
HKD1_k127_3756264_21 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000205 67.0
HKD1_k127_3756264_22 Protein of unknown function (DUF1624) K10532 GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005765,GO:0005773,GO:0005774,GO:0005886,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0007034,GO:0007041,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0012505,GO:0012506,GO:0015019,GO:0016020,GO:0016043,GO:0016192,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0022607,GO:0030141,GO:0030203,GO:0030659,GO:0030667,GO:0031090,GO:0031410,GO:0031982,GO:0032940,GO:0035579,GO:0036230,GO:0042119,GO:0042581,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043299,GO:0043312,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0051259,GO:0065003,GO:0070820,GO:0070821,GO:0071704,GO:0071840,GO:0071944,GO:0097708,GO:0098588,GO:0098805,GO:0098852,GO:0099503,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 2.3.1.78 0.000008583 56.0
HKD1_k127_3756264_3 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 472.0
HKD1_k127_3756264_4 import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 396.0
HKD1_k127_3756264_5 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 350.0
HKD1_k127_3756264_6 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 302.0
HKD1_k127_3756264_7 binding-protein-dependent transport systems inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 291.0
HKD1_k127_3756264_8 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 295.0
HKD1_k127_3756264_9 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001183 286.0
HKD1_k127_377586_0 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 596.0
HKD1_k127_377586_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 556.0
HKD1_k127_377586_10 B12 binding domain - - - 0.00003522 46.0
HKD1_k127_377586_11 - - - - 0.00008661 49.0
HKD1_k127_377586_2 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009703 520.0
HKD1_k127_377586_3 COGs COG0569 K transport systems NAD-binding component K03499,K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 367.0
HKD1_k127_377586_4 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002715 276.0
HKD1_k127_377586_5 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000003074 256.0
HKD1_k127_377586_6 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000007109 260.0
HKD1_k127_377586_7 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000055 136.0
HKD1_k127_377586_8 RNA recognition motif - - - 0.000000000000000000000000000003412 124.0
HKD1_k127_377586_9 Virulence factor - - - 0.000000007194 65.0
HKD1_k127_3801743_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007882 257.0
HKD1_k127_3801743_1 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000001985 188.0
HKD1_k127_382762_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 494.0
HKD1_k127_382762_1 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 460.0
HKD1_k127_382762_10 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 337.0
HKD1_k127_382762_11 FemAB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 327.0
HKD1_k127_382762_12 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 327.0
HKD1_k127_382762_13 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 297.0
HKD1_k127_382762_14 Glycosyl transferases group 1 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 306.0
HKD1_k127_382762_15 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003006 276.0
HKD1_k127_382762_16 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000001269 222.0
HKD1_k127_382762_17 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000007464 215.0
HKD1_k127_382762_18 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000001483 216.0
HKD1_k127_382762_19 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000001901 189.0
HKD1_k127_382762_2 asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 451.0
HKD1_k127_382762_20 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000001085 188.0
HKD1_k127_382762_21 YsiA-like protein, C-terminal region K13770 - - 0.00000000000000000000000000000000000000000000001745 177.0
HKD1_k127_382762_22 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001646 175.0
HKD1_k127_382762_23 Polysaccharide biosynthesis/export protein - - - 0.00000000000000000000000000000000000000000004814 170.0
HKD1_k127_382762_25 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000002054 181.0
HKD1_k127_382762_26 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000008125 177.0
HKD1_k127_382762_27 G-rich domain on putative tyrosine kinase - - - 0.00000000000000000000000000000000000001691 166.0
HKD1_k127_382762_28 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000001001 159.0
HKD1_k127_382762_29 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000001852 139.0
HKD1_k127_382762_3 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 398.0
HKD1_k127_382762_30 Glycosyl transferase 4-like domain K03525 - 2.7.1.33 0.00000000000000000000001367 115.0
HKD1_k127_382762_31 PHP family - - - 0.000000000000000000001023 102.0
HKD1_k127_382762_32 response regulator, receiver - - - 0.0000000000000000001005 93.0
HKD1_k127_382762_33 Sugar transferase, PEP-CTERM EpsH1 system associated - - - 0.0000000397 63.0
HKD1_k127_382762_34 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00005545 54.0
HKD1_k127_382762_35 Diguanylate cyclase K13069 - 2.7.7.65 0.0004444 50.0
HKD1_k127_382762_4 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 378.0
HKD1_k127_382762_5 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 374.0
HKD1_k127_382762_6 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 384.0
HKD1_k127_382762_7 protein involved in propionate catabolism - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 351.0
HKD1_k127_382762_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 340.0
HKD1_k127_382762_9 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 346.0
HKD1_k127_3850800_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 389.0
HKD1_k127_3850800_1 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 299.0
HKD1_k127_3850800_10 Major Facilitator Superfamily - - - 0.00000000000000000000004 114.0
HKD1_k127_3850800_11 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - - 0.000000000005164 75.0
HKD1_k127_3850800_12 - - - - 0.00004519 48.0
HKD1_k127_3850800_2 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K19550 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0016999,GO:0017000,GO:0017144,GO:0036094,GO:0044237,GO:0044249,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000441 282.0
HKD1_k127_3850800_3 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004415 263.0
HKD1_k127_3850800_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000002121 245.0
HKD1_k127_3850800_5 amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000008424 235.0
HKD1_k127_3850800_6 (ABC) transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000001273 236.0
HKD1_k127_3850800_7 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000001728 211.0
HKD1_k127_3850800_8 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000005524 216.0
HKD1_k127_3850800_9 mandelate racemase muconate lactonizing - - - 0.000000000000000000000000000000000000000005019 156.0
HKD1_k127_3868671_0 PFAM FAD linked oxidase domain protein - - - 2.718e-317 1001.0
HKD1_k127_3868671_1 nitrite reductase K00368 - 1.7.2.1 2.18e-240 751.0
HKD1_k127_3868671_10 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 497.0
HKD1_k127_3868671_11 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 492.0
HKD1_k127_3868671_12 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 509.0
HKD1_k127_3868671_13 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 460.0
HKD1_k127_3868671_14 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 428.0
HKD1_k127_3868671_15 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 429.0
HKD1_k127_3868671_16 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 404.0
HKD1_k127_3868671_17 TIGRFAM gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 391.0
HKD1_k127_3868671_18 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 351.0
HKD1_k127_3868671_19 PFAM Alcohol dehydrogenase GroES-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 338.0
HKD1_k127_3868671_2 helicase superfamily c-terminal domain K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 1.525e-227 732.0
HKD1_k127_3868671_20 PFAM CBS domain containing protein K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 339.0
HKD1_k127_3868671_21 C4-dicarboxylate transporter, substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 324.0
HKD1_k127_3868671_22 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 331.0
HKD1_k127_3868671_23 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K21416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 291.0
HKD1_k127_3868671_24 Two component transcriptional regulator, winged helix family K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003977 284.0
HKD1_k127_3868671_25 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009024 274.0
HKD1_k127_3868671_26 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001692 269.0
HKD1_k127_3868671_27 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000003037 224.0
HKD1_k127_3868671_28 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000002074 208.0
HKD1_k127_3868671_29 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K03778 - 1.1.1.28,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000408 203.0
HKD1_k127_3868671_3 phosphate transport system permease protein K02038 - - 6.7e-212 686.0
HKD1_k127_3868671_30 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000006257 190.0
HKD1_k127_3868671_31 transport system periplasmic component K01989 - - 0.00000000000000000000000000000000000000000000001902 183.0
HKD1_k127_3868671_32 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000001456 182.0
HKD1_k127_3868671_33 Two component transcriptional regulator, winged helix family K07658,K07668 - - 0.0000000000000000000000000000000000000000000009513 175.0
HKD1_k127_3868671_34 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000006766 169.0
HKD1_k127_3868671_35 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000001139 176.0
HKD1_k127_3868671_36 Response regulator receiver - - - 0.000000000000000001408 87.0
HKD1_k127_3868671_37 Belongs to the protein N5-glutamine methyltransferase family - - - 0.00000000000000003838 94.0
HKD1_k127_3868671_38 Thioredoxin-like - - - 0.000000000000000389 89.0
HKD1_k127_3868671_39 Phosphonate metabolism protein PhnG K06166 - 2.7.8.37 0.0000000004629 65.0
HKD1_k127_3868671_4 PFAM AMP-dependent synthetase and ligase - - - 8.944e-198 633.0
HKD1_k127_3868671_40 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000114 55.0
HKD1_k127_3868671_41 - - - - 0.000001725 60.0
HKD1_k127_3868671_42 ABC-type cobalt transport system ATPase component K02006 - - 0.0001871 52.0
HKD1_k127_3868671_43 Binding-protein-dependent transport system inner membrane component - - - 0.0001907 45.0
HKD1_k127_3868671_5 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 626.0
HKD1_k127_3868671_6 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 595.0
HKD1_k127_3868671_7 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 537.0
HKD1_k127_3868671_8 PFAM Transketolase central region K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 520.0
HKD1_k127_3868671_9 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 527.0
HKD1_k127_3907443_0 transmembrane transporter activity K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 383.0
HKD1_k127_3907443_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000005923 242.0
HKD1_k127_3907443_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000006585 183.0
HKD1_k127_3907443_3 PFAM Outer membrane efflux protein K03287 - - 0.000000000000000000000017 115.0
HKD1_k127_3916592_0 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 446.0
HKD1_k127_3916592_1 Histidine kinase K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000001015 231.0
HKD1_k127_4027295_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 5.622e-266 829.0
HKD1_k127_4027295_1 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 417.0
HKD1_k127_4027295_10 PFAM SMP-30 Gluconolaconase - - - 0.0001827 53.0
HKD1_k127_4027295_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 411.0
HKD1_k127_4027295_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 374.0
HKD1_k127_4027295_4 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 345.0
HKD1_k127_4027295_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 291.0
HKD1_k127_4027295_6 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002159 286.0
HKD1_k127_4027295_7 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000001618 124.0
HKD1_k127_4027295_8 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000002233 104.0
HKD1_k127_4027295_9 - K17226 - - 0.00000000000001061 77.0
HKD1_k127_4028708_0 Urease alpha-subunit, N-terminal domain K01428 - 3.5.1.5 5.671e-284 887.0
HKD1_k127_4028708_1 Periplasmic binding protein domain K01999 - - 9.946e-195 621.0
HKD1_k127_4028708_2 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 472.0
HKD1_k127_4028708_3 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 393.0
HKD1_k127_4028708_4 TIGRFAM ABC transporter, urea, permease protein, UrtC K01998,K11961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 377.0
HKD1_k127_4028708_5 TIGRFAM ABC transporter, urea, ATP-binding protein, UrtD K11962 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 321.0
HKD1_k127_4028708_6 ATPases associated with a variety of cellular activities K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000000002969 242.0
HKD1_k127_4028708_7 Belongs to the urease gamma subunit family K01430,K14048 - 3.5.1.5 0.000000000000000000000000000000000000000000001854 166.0
HKD1_k127_4028708_8 PFAM Urease beta subunit K01429,K14048 - 3.5.1.5 0.000000000000000000000000000000000000000000002743 167.0
HKD1_k127_4030668_0 DEAD DEAH box K03724 - - 0.0 1631.0
HKD1_k127_4030668_1 Carbamoyltransferase C-terminus K00612 - - 8.058e-301 931.0
HKD1_k127_4030668_10 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 504.0
HKD1_k127_4030668_11 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 411.0
HKD1_k127_4030668_12 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 389.0
HKD1_k127_4030668_13 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 331.0
HKD1_k127_4030668_14 PFAM ABC transporter related K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 334.0
HKD1_k127_4030668_15 NMT1 THI5-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 328.0
HKD1_k127_4030668_16 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 335.0
HKD1_k127_4030668_17 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 303.0
HKD1_k127_4030668_18 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001727 266.0
HKD1_k127_4030668_19 Binding-protein-dependent transport system inner membrane component K10003 - - 0.0000000000000000000000000000000000000000000000000000000000000005065 229.0
HKD1_k127_4030668_2 Bacterial DNA polymerase III alpha subunit - - - 3.208e-238 783.0
HKD1_k127_4030668_20 fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000003353 222.0
HKD1_k127_4030668_21 transferase activity, transferring glycosyl groups K20444 - - 0.0000000000000000000000000000000000000000000000000000000001104 218.0
HKD1_k127_4030668_22 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000003699 214.0
HKD1_k127_4030668_23 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.00000000000000000000000000000000000000000000000000000004594 214.0
HKD1_k127_4030668_24 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000000000000000000000000000000000000000000001305 213.0
HKD1_k127_4030668_25 Putative molybdenum carrier - - - 0.0000000000000000000000000000000000000000000000000001137 190.0
HKD1_k127_4030668_26 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000000000000000006497 189.0
HKD1_k127_4030668_27 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000007799 195.0
HKD1_k127_4030668_28 Thiamine-binding protein - - - 0.00000000000000000000000000000000000000000005326 164.0
HKD1_k127_4030668_29 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000000000000000000000006686 169.0
HKD1_k127_4030668_3 dehydrogenase - - - 2.167e-203 657.0
HKD1_k127_4030668_30 - - - - 0.0000000000000000000000000000000000000001608 157.0
HKD1_k127_4030668_31 Methyltransferase domain - - - 0.000000000000000000000000000000000000071 147.0
HKD1_k127_4030668_32 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000001481 160.0
HKD1_k127_4030668_33 dehydratase - - - 0.00000000000000000000000000000000000166 150.0
HKD1_k127_4030668_34 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000597 151.0
HKD1_k127_4030668_35 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000001163 141.0
HKD1_k127_4030668_36 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000001559 134.0
HKD1_k127_4030668_37 - - - - 0.00000000000000000000000000006824 126.0
HKD1_k127_4030668_38 radical SAM domain protein - - - 0.0000000000000000000000000005645 118.0
HKD1_k127_4030668_39 cyclic nucleotide binding K10914 - - 0.000000000000000000000000001058 119.0
HKD1_k127_4030668_4 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 1.853e-194 623.0
HKD1_k127_4030668_40 Biotin-lipoyl like K01960,K01965,K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1,6.4.1.3,6.4.1.4 0.00000000000000000000000004136 120.0
HKD1_k127_4030668_41 Oxidoreductase FAD-binding domain K16246 - - 0.00000000000000000000007643 108.0
HKD1_k127_4030668_43 lipolytic protein G-D-S-L family - - - 0.000000000000000000364 100.0
HKD1_k127_4030668_44 radical SAM domain protein - - - 0.000000000000000008986 91.0
HKD1_k127_4030668_45 - - - - 0.0000000000000003413 81.0
HKD1_k127_4030668_46 Haem-degrading - - - 0.0000000000007279 76.0
HKD1_k127_4030668_47 recA bacterial DNA recombination protein - - - 0.00000000005752 71.0
HKD1_k127_4030668_48 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000002386 69.0
HKD1_k127_4030668_5 protein conserved in bacteria K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 584.0
HKD1_k127_4030668_50 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00007999 56.0
HKD1_k127_4030668_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 609.0
HKD1_k127_4030668_7 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 584.0
HKD1_k127_4030668_8 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 552.0
HKD1_k127_4030668_9 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 551.0
HKD1_k127_4030920_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 584.0
HKD1_k127_4030920_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 542.0
HKD1_k127_4030920_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005471 289.0
HKD1_k127_4030920_11 Sugar transferase, PEP-CTERM EpsH1 system associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000002151 238.0
HKD1_k127_4030920_12 Subtilase family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000003759 237.0
HKD1_k127_4030920_13 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000001245 170.0
HKD1_k127_4030920_14 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000001618 149.0
HKD1_k127_4030920_15 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000001837 147.0
HKD1_k127_4030920_16 Methyltransferase domain - - - 0.00000000000000000000000000000007264 137.0
HKD1_k127_4030920_17 Phosphotransferase enzyme family - - - 0.00000002553 65.0
HKD1_k127_4030920_18 transmembrane protein EpsH - - - 0.00000007246 65.0
HKD1_k127_4030920_19 transferase activity, transferring glycosyl groups K20444 - - 0.00003487 52.0
HKD1_k127_4030920_2 phosphorelay signal transduction system K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 471.0
HKD1_k127_4030920_20 Nitrous oxidase accessory protein - - - 0.00005483 55.0
HKD1_k127_4030920_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 428.0
HKD1_k127_4030920_4 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 398.0
HKD1_k127_4030920_5 Wzy family polymerase, exosortase system type 1 associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 373.0
HKD1_k127_4030920_6 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 373.0
HKD1_k127_4030920_7 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 363.0
HKD1_k127_4030920_8 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 295.0
HKD1_k127_4030920_9 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002621 289.0
HKD1_k127_4035395_0 Dehydrogenase - - - 1.973e-224 718.0
HKD1_k127_4035395_1 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 616.0
HKD1_k127_4035395_2 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 546.0
HKD1_k127_4035395_3 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 458.0
HKD1_k127_4035395_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 331.0
HKD1_k127_4035395_5 endonuclease activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 306.0
HKD1_k127_4035395_6 tRNA rRNA methyltransferase, SpoU - - - 0.0000000000000000000000000000000000003887 145.0
HKD1_k127_4035395_7 YbaK prolyl-tRNA synthetase associated region - - - 0.0000000000000000000000000000000000005106 157.0
HKD1_k127_4035395_8 Protein conserved in bacteria - - - 0.000000000000291 78.0
HKD1_k127_4035395_9 YwiC-like protein - - - 0.0000004448 60.0
HKD1_k127_4039413_0 ABC-type dipeptide transport system periplasmic component K02035 - - 2.92e-257 801.0
HKD1_k127_4039413_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 460.0
HKD1_k127_4039413_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 443.0
HKD1_k127_4039413_3 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 407.0
HKD1_k127_4039413_4 Conserved protein of dim6 ntab family - - - 0.0000000000000000000000000000000000000000000000000000000000005629 219.0
HKD1_k127_4039413_5 In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.000000000000000000001998 97.0
HKD1_k127_4039413_6 Glycine reductase complex selenoprotein A K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.000006207 58.0
HKD1_k127_4042147_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.758e-268 838.0
HKD1_k127_4042147_1 Adenylate and Guanylate cyclase catalytic domain - - - 8.575e-243 786.0
HKD1_k127_4042147_10 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 412.0
HKD1_k127_4042147_11 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 417.0
HKD1_k127_4042147_12 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 399.0
HKD1_k127_4042147_13 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 381.0
HKD1_k127_4042147_14 conserved protein (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 384.0
HKD1_k127_4042147_15 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 374.0
HKD1_k127_4042147_16 Belongs to the D-glutamate cyclase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 357.0
HKD1_k127_4042147_17 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 343.0
HKD1_k127_4042147_18 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 340.0
HKD1_k127_4042147_19 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006814 284.0
HKD1_k127_4042147_2 Amino acid permease - - - 2.388e-204 653.0
HKD1_k127_4042147_20 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001724 272.0
HKD1_k127_4042147_21 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001654 258.0
HKD1_k127_4042147_22 DNA polymerase alpha chain like domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.00000000000000000000000000000000000000000000000000000000000000000000000004983 259.0
HKD1_k127_4042147_23 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000000000000000000000004656 230.0
HKD1_k127_4042147_24 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000009401 222.0
HKD1_k127_4042147_25 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001982 232.0
HKD1_k127_4042147_26 Allophanate hydrolase subunit 1 K06351 - - 0.0000000000000000000000000000000000000000000000000000000000006036 222.0
HKD1_k127_4042147_27 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000000000006101 189.0
HKD1_k127_4042147_28 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000307 175.0
HKD1_k127_4042147_29 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000001045 149.0
HKD1_k127_4042147_3 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 2.119e-203 647.0
HKD1_k127_4042147_30 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000005289 146.0
HKD1_k127_4042147_31 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.0000000000000000000000000000000101 139.0
HKD1_k127_4042147_32 NUDIX domain - - - 0.000000000000000000000000000000116 129.0
HKD1_k127_4042147_33 Acyl-CoA synthetase (NDP forming) - - - 0.0000000000000000000000000000001745 132.0
HKD1_k127_4042147_34 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000003061 117.0
HKD1_k127_4042147_35 PFAM Uncharacterised ACR, COG1259 K08999 - - 0.0000000000000000000000000004797 120.0
HKD1_k127_4042147_36 PFAM thioesterase superfamily K07107 - - 0.000000000000000000000005506 111.0
HKD1_k127_4042147_37 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000004922 72.0
HKD1_k127_4042147_38 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000002242 58.0
HKD1_k127_4042147_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 5.581e-195 619.0
HKD1_k127_4042147_5 Glucose inhibited division protein A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 602.0
HKD1_k127_4042147_6 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 507.0
HKD1_k127_4042147_7 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 475.0
HKD1_k127_4042147_8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 474.0
HKD1_k127_4042147_9 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 456.0
HKD1_k127_4042214_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 1.702e-318 995.0
HKD1_k127_4042214_1 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 514.0
HKD1_k127_4042214_10 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000001994 228.0
HKD1_k127_4042214_11 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000415 227.0
HKD1_k127_4042214_12 Glycosyl transferases group 1 K02844 - - 0.0000000000000000000000000000000000000000000000000000000003302 221.0
HKD1_k127_4042214_13 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000007419 191.0
HKD1_k127_4042214_14 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02527,K02841,K02843,K12982 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000002526 191.0
HKD1_k127_4042214_15 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000002896 186.0
HKD1_k127_4042214_16 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000946 152.0
HKD1_k127_4042214_17 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000002617 140.0
HKD1_k127_4042214_18 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000202 124.0
HKD1_k127_4042214_19 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000008139 129.0
HKD1_k127_4042214_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 337.0
HKD1_k127_4042214_20 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000001098 81.0
HKD1_k127_4042214_21 Glycosyl transferase family 2 K12984 - - 0.000000000000007284 84.0
HKD1_k127_4042214_22 Outer membrane protein (OmpH-like) K06142 - - 0.000000004477 68.0
HKD1_k127_4042214_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 321.0
HKD1_k127_4042214_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 307.0
HKD1_k127_4042214_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002345 294.0
HKD1_k127_4042214_6 inositol 2-dehydrogenase activity K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007114 288.0
HKD1_k127_4042214_7 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007516 250.0
HKD1_k127_4042214_8 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000001217 245.0
HKD1_k127_4042214_9 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000005093 219.0
HKD1_k127_4049039_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 543.0
HKD1_k127_4049039_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009558 383.0
HKD1_k127_4049039_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 391.0
HKD1_k127_4049039_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 372.0
HKD1_k127_4049039_4 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000001434 247.0
HKD1_k127_4049039_5 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000008524 243.0
HKD1_k127_4049039_6 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000002541 239.0
HKD1_k127_4049039_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000001548 108.0
HKD1_k127_4049039_8 - - - - 0.000000000000000001146 101.0
HKD1_k127_4049039_9 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.000001933 52.0
HKD1_k127_4068109_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 379.0
HKD1_k127_4068109_1 - - - - 0.00000003136 59.0
HKD1_k127_4074436_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1118.0
HKD1_k127_4074436_1 (GMC) oxidoreductase K00108 - 1.1.99.1 9.834e-242 757.0
HKD1_k127_4074436_10 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 379.0
HKD1_k127_4074436_11 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 326.0
HKD1_k127_4074436_12 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 323.0
HKD1_k127_4074436_13 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 313.0
HKD1_k127_4074436_14 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007528 266.0
HKD1_k127_4074436_15 haloacid dehalogenase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000001538 254.0
HKD1_k127_4074436_16 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008097 244.0
HKD1_k127_4074436_17 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000001823 238.0
HKD1_k127_4074436_18 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000009265 216.0
HKD1_k127_4074436_19 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000005666 183.0
HKD1_k127_4074436_2 acetyl-coa acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 549.0
HKD1_k127_4074436_20 Histidine kinase K02482,K03557 - 2.7.13.3 0.0000000000000000000000000000000000000000000002285 185.0
HKD1_k127_4074436_21 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000009051 171.0
HKD1_k127_4074436_22 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000004406 142.0
HKD1_k127_4074436_23 surface antigen - - - 0.00000000000000000000000000000000008887 140.0
HKD1_k127_4074436_24 Resolvase, N terminal domain - - - 0.000000000000000000000008283 104.0
HKD1_k127_4074436_25 Flavin-nucleotide-binding protein K07005 - - 0.000000000000000000001742 109.0
HKD1_k127_4074436_26 PIN domain - - - 0.0000000000000001657 84.0
HKD1_k127_4074436_28 EF-hand, calcium binding motif - - - 0.0000000000004319 74.0
HKD1_k127_4074436_29 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000003653 58.0
HKD1_k127_4074436_3 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 519.0
HKD1_k127_4074436_30 amidohydrolase - - - 0.0006641 50.0
HKD1_k127_4074436_4 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 476.0
HKD1_k127_4074436_5 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 474.0
HKD1_k127_4074436_6 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 465.0
HKD1_k127_4074436_7 4-phosphoerythronate dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 434.0
HKD1_k127_4074436_8 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 398.0
HKD1_k127_4074436_9 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 385.0
HKD1_k127_4075267_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 507.0
HKD1_k127_4075267_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 411.0
HKD1_k127_4075267_10 alpha beta - - - 0.000000000000000001257 98.0
HKD1_k127_4075267_11 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0002425 44.0
HKD1_k127_4075267_12 COG2015, Alkyl sulfatase and related hydrolases - - - 0.0006139 49.0
HKD1_k127_4075267_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 333.0
HKD1_k127_4075267_3 Phosphomethylpyrimidine kinase K00941,K03147,K21219 GO:0008150,GO:0040007 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 299.0
HKD1_k127_4075267_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000013 294.0
HKD1_k127_4075267_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000005602 254.0
HKD1_k127_4075267_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000004833 252.0
HKD1_k127_4075267_7 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000005537 239.0
HKD1_k127_4075267_8 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000001878 199.0
HKD1_k127_4075267_9 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000005532 129.0
HKD1_k127_4075952_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 2.02e-232 727.0
HKD1_k127_4075952_1 40-residue yvtn family beta-propeller repeat protein - - - 2.373e-195 618.0
HKD1_k127_4075952_10 PFAM CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003007 275.0
HKD1_k127_4075952_11 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000004538 240.0
HKD1_k127_4075952_12 Lysine methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000002154 207.0
HKD1_k127_4075952_13 alpha beta - - - 0.000000000000000000000000000000000000000000000003193 191.0
HKD1_k127_4075952_14 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000001108 161.0
HKD1_k127_4075952_16 Domain of unknown function (DUF305) - - - 0.00000000000000000000004405 115.0
HKD1_k127_4075952_17 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275,K02826,K15864 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016679,GO:0016682,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.10.3.12,1.7.2.1,1.7.99.1,1.9.3.1 0.0000000000000000001976 95.0
HKD1_k127_4075952_18 - K02275,K17686 - 1.9.3.1,3.6.3.54 0.000000000000000000586 100.0
HKD1_k127_4075952_19 Protein of unknown function with PCYCGC motif - - - 0.000000000000000001534 95.0
HKD1_k127_4075952_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 456.0
HKD1_k127_4075952_20 - - - - 0.000000000004569 79.0
HKD1_k127_4075952_21 Protein of unknown function with PCYCGC motif - - - 0.0000001186 53.0
HKD1_k127_4075952_3 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 408.0
HKD1_k127_4075952_4 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 397.0
HKD1_k127_4075952_5 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 396.0
HKD1_k127_4075952_6 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 383.0
HKD1_k127_4075952_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 361.0
HKD1_k127_4075952_8 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009761 284.0
HKD1_k127_4075952_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000003791 273.0
HKD1_k127_4090834_0 4Fe-4S binding domain - - - 1.308e-206 656.0
HKD1_k127_4090834_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 616.0
HKD1_k127_4090834_10 Aldo/keto reductase family K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 351.0
HKD1_k127_4090834_11 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 372.0
HKD1_k127_4090834_12 Dehydrogenase E1 component K21416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 317.0
HKD1_k127_4090834_13 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 312.0
HKD1_k127_4090834_14 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 323.0
HKD1_k127_4090834_15 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 314.0
HKD1_k127_4090834_16 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003096 285.0
HKD1_k127_4090834_17 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003933 268.0
HKD1_k127_4090834_18 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000626 259.0
HKD1_k127_4090834_19 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000182 228.0
HKD1_k127_4090834_2 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 514.0
HKD1_k127_4090834_20 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000001387 208.0
HKD1_k127_4090834_21 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000004415 182.0
HKD1_k127_4090834_22 Histidine kinase - - - 0.00000000000000000000000000000000000000000001121 180.0
HKD1_k127_4090834_23 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000001016 146.0
HKD1_k127_4090834_24 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000001186 149.0
HKD1_k127_4090834_25 PFAM ATP-binding region ATPase domain protein K07709 - 2.7.13.3 0.00000000000000000000000000000004027 144.0
HKD1_k127_4090834_26 Sigma-54 interaction domain K07714,K07715 - - 0.000000000000000000000000004845 128.0
HKD1_k127_4090834_27 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000008955 111.0
HKD1_k127_4090834_28 - - - - 0.0000000000000203 85.0
HKD1_k127_4090834_3 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 523.0
HKD1_k127_4090834_30 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.0000000001383 74.0
HKD1_k127_4090834_31 Biotin-requiring enzyme K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000003886 72.0
HKD1_k127_4090834_33 Thioesterase superfamily protein K07107 - - 0.0001145 48.0
HKD1_k127_4090834_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 482.0
HKD1_k127_4090834_5 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 472.0
HKD1_k127_4090834_6 PFAM Transketolase K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 414.0
HKD1_k127_4090834_7 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 392.0
HKD1_k127_4090834_8 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 383.0
HKD1_k127_4090834_9 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 356.0
HKD1_k127_4100255_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 515.0
HKD1_k127_4100255_1 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 322.0
HKD1_k127_4100255_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000007434 207.0
HKD1_k127_4100255_3 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000002838 197.0
HKD1_k127_4100255_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000001077 194.0
HKD1_k127_4100255_5 hydrolase (HAD superfamily) K07025 - - 0.000000000000000000000000000000004051 138.0
HKD1_k127_4100255_6 hydrolase (HAD superfamily) K07025 - - 0.00000000000000000000000000004797 128.0
HKD1_k127_4100255_7 PFAM Pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000001493 120.0
HKD1_k127_4100255_8 Rhodanese Homology Domain - - - 0.0000000000000000000000004671 108.0
HKD1_k127_4100255_9 MFS_1 like family - - - 0.00000000000000000123 99.0
HKD1_k127_4101164_0 Belongs to the ABC transporter superfamily K02031,K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 464.0
HKD1_k127_4101164_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005505 290.0
HKD1_k127_4101164_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001001 266.0
HKD1_k127_4101164_3 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002919 274.0
HKD1_k127_4101164_4 ABC-2 type transporter K01992 - - 0.0006317 43.0
HKD1_k127_4111678_0 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002009 271.0
HKD1_k127_4111678_1 Major Facilitator Superfamily - - - 0.0000000000000000000000005631 121.0
HKD1_k127_4113238_0 Radical SAM - - - 1.333e-215 679.0
HKD1_k127_4113238_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 514.0
HKD1_k127_4113238_10 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001829 293.0
HKD1_k127_4113238_11 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009453 276.0
HKD1_k127_4113238_12 COG0644 Dehydrogenases (flavoproteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001995 277.0
HKD1_k127_4113238_13 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000001134 266.0
HKD1_k127_4113238_14 Belongs to the malate synthase family K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000009938 264.0
HKD1_k127_4113238_15 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000004142 225.0
HKD1_k127_4113238_16 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000316 223.0
HKD1_k127_4113238_17 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000008962 194.0
HKD1_k127_4113238_18 Formate hydrogenlyase K12136,K15827 - - 0.000000000000000000000000000000000000000000000000007899 186.0
HKD1_k127_4113238_19 dehydratase - - - 0.00000000000000000000000000000000000000000000002463 184.0
HKD1_k127_4113238_2 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 486.0
HKD1_k127_4113238_20 EamA-like transporter family K03298 - - 0.0000000000000000000000000000000000000000001873 171.0
HKD1_k127_4113238_21 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000006812 174.0
HKD1_k127_4113238_22 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000003039 165.0
HKD1_k127_4113238_23 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000002211 163.0
HKD1_k127_4113238_24 peptidase m48, ste24p - - - 0.000000000000000000000000000000000006354 151.0
HKD1_k127_4113238_25 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000003463 137.0
HKD1_k127_4113238_26 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000007086 143.0
HKD1_k127_4113238_27 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000000000000000000000004013 131.0
HKD1_k127_4113238_28 GYD domain - - - 0.00000000000000000000000007197 117.0
HKD1_k127_4113238_29 MacB-like periplasmic core domain K02004 - - 0.0000000000000001769 94.0
HKD1_k127_4113238_3 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 459.0
HKD1_k127_4113238_30 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.00000000002982 71.0
HKD1_k127_4113238_31 - - - - 0.0000000001627 66.0
HKD1_k127_4113238_32 - - - - 0.000000006279 61.0
HKD1_k127_4113238_33 - - - - 0.000002436 52.0
HKD1_k127_4113238_4 FGGY family of carbohydrate kinases, C-terminal domain K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 414.0
HKD1_k127_4113238_5 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 370.0
HKD1_k127_4113238_6 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 336.0
HKD1_k127_4113238_7 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009436,GO:0009442,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042737,GO:0043436,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046700,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 314.0
HKD1_k127_4113238_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 304.0
HKD1_k127_4113238_9 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 299.0
HKD1_k127_4127570_0 non-ribosomal peptide synthetase K16416 - - 0.0 1630.0
HKD1_k127_4127570_1 Adenylate and Guanylate cyclase catalytic domain - - - 1e-323 1026.0
HKD1_k127_4127570_10 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000001333 200.0
HKD1_k127_4127570_11 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000003311 181.0
HKD1_k127_4127570_12 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000694 132.0
HKD1_k127_4127570_13 Selenoprotein B, glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.000000000000000000001468 96.0
HKD1_k127_4127570_14 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K21577 - 1.21.4.2,1.21.4.3,1.21.4.4 0.00000000000000000003972 104.0
HKD1_k127_4127570_15 - - - - 0.0000000000000000003246 98.0
HKD1_k127_4127570_16 Mo-molybdopterin cofactor metabolic process K03636 - - 0.0000001134 61.0
HKD1_k127_4127570_17 - - - - 0.0000003065 55.0
HKD1_k127_4127570_18 - - - - 0.000003126 53.0
HKD1_k127_4127570_19 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000003453 60.0
HKD1_k127_4127570_2 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 502.0
HKD1_k127_4127570_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 402.0
HKD1_k127_4127570_4 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 396.0
HKD1_k127_4127570_5 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 364.0
HKD1_k127_4127570_6 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 342.0
HKD1_k127_4127570_7 Selenoprotein B, glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000176 272.0
HKD1_k127_4127570_8 PFAM Glycine sarcosine betaine reductase complex, protein B, alpha and beta subunits K10671 - 1.21.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000001996 257.0
HKD1_k127_4127570_9 phosphatidylinositol metabolic process K00728 - 2.4.1.109 0.000000000000000000000000000000000000000000000000000003208 208.0
HKD1_k127_414515_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 1.053e-254 794.0
HKD1_k127_414515_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 2.953e-241 768.0
HKD1_k127_414515_10 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 406.0
HKD1_k127_414515_11 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 391.0
HKD1_k127_414515_12 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 382.0
HKD1_k127_414515_13 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 362.0
HKD1_k127_414515_14 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 310.0
HKD1_k127_414515_15 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000004409 211.0
HKD1_k127_414515_16 - - - - 0.000000000000000000000000000000000000000000000000000005361 200.0
HKD1_k127_414515_17 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000001118 166.0
HKD1_k127_414515_18 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000009087 158.0
HKD1_k127_414515_19 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000001344 150.0
HKD1_k127_414515_2 Amino acid permease - - - 1.291e-197 633.0
HKD1_k127_414515_20 Cell shape-determining protein MreC K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - 0.000000000000000000000000000000000004501 148.0
HKD1_k127_414515_21 SMART HNH nuclease K07451 - - 0.00000000000000000000000000000000005323 138.0
HKD1_k127_414515_22 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000816 140.0
HKD1_k127_414515_23 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000000000000000000001965 134.0
HKD1_k127_414515_24 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000000124 143.0
HKD1_k127_414515_25 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.00000000000000000000000000000001333 132.0
HKD1_k127_414515_26 Cold shock protein K03704 - - 0.0000000000000000000000000001624 115.0
HKD1_k127_414515_27 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000002303 109.0
HKD1_k127_414515_28 Cold shock protein K03704 - - 0.000000000000000000000000121 110.0
HKD1_k127_414515_29 protein, possibly involved in aromatic compounds catabolism K02614 - - 0.00000000000000001455 96.0
HKD1_k127_414515_3 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 581.0
HKD1_k127_414515_30 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000001977 87.0
HKD1_k127_414515_31 PFAM YHS domain - - - 0.00000000000001481 74.0
HKD1_k127_414515_32 TIGRFAM competence protein ComEA helix-hairpin-helix repeat region K02237 - - 0.0000000000272 68.0
HKD1_k127_414515_33 ABC transporter substrate binding protein K01989 - - 0.0000001494 57.0
HKD1_k127_414515_34 - - - - 0.0000004038 60.0
HKD1_k127_414515_35 Protein of unknown function (DUF2889) - - - 0.00000942 57.0
HKD1_k127_414515_36 Protein of unknown function (DUF971) - - - 0.000009512 55.0
HKD1_k127_414515_37 rod shape-determining protein (MreD) K03571 - - 0.0001933 51.0
HKD1_k127_414515_4 MreB/Mbl protein K03569 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 498.0
HKD1_k127_414515_5 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 496.0
HKD1_k127_414515_6 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 501.0
HKD1_k127_414515_7 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 479.0
HKD1_k127_414515_8 mannitol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 452.0
HKD1_k127_414515_9 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 403.0
HKD1_k127_4179926_0 transmembrane transporter activity K03296 - - 8.407e-220 702.0
HKD1_k127_4179926_1 TIGRFAM 2-hydroxy-3-oxopropionate reductase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000165 171.0
HKD1_k127_4179926_2 SpoVT / AbrB like domain - - - 0.0000148 54.0
HKD1_k127_4221726_0 X-Pro dipeptidyl-peptidase domain protein K06978 - - 1.613e-241 763.0
HKD1_k127_4221726_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.466e-202 642.0
HKD1_k127_4221726_10 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003108 257.0
HKD1_k127_4221726_11 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004681 252.0
HKD1_k127_4221726_12 Peroxidase K07223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000256 251.0
HKD1_k127_4221726_13 OmpA family - - - 0.000000000000000000000000000000000000002802 163.0
HKD1_k127_4221726_14 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000008808 149.0
HKD1_k127_4221726_15 FecR protein - - - 0.00000000000000000000000000000001826 136.0
HKD1_k127_4221726_16 Predicted membrane protein (DUF2214) K08983 - - 0.0000000000000000000000000000001265 128.0
HKD1_k127_4221726_17 STAS domain K06378 - - 0.00000000000000000000001446 105.0
HKD1_k127_4221726_18 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000003785 80.0
HKD1_k127_4221726_19 Polysulphide reductase, NrfD - - - 0.0000000001773 70.0
HKD1_k127_4221726_2 CHASE2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 561.0
HKD1_k127_4221726_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 433.0
HKD1_k127_4221726_4 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 377.0
HKD1_k127_4221726_5 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 379.0
HKD1_k127_4221726_6 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 312.0
HKD1_k127_4221726_7 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 299.0
HKD1_k127_4221726_8 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001145 289.0
HKD1_k127_4221726_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001101 249.0
HKD1_k127_4271745_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 1.291e-198 662.0
HKD1_k127_4271745_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 478.0
HKD1_k127_4271745_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004233 276.0
HKD1_k127_4296790_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0 1035.0
HKD1_k127_4296790_1 Protein of unknown function (DUF3141) - - - 8.482e-244 780.0
HKD1_k127_4296790_2 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 503.0
HKD1_k127_4296790_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 487.0
HKD1_k127_4296790_4 PFAM phosphate acetyl butaryl transferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 435.0
HKD1_k127_4296790_5 - - - - 0.00000000000000000000002836 107.0
HKD1_k127_4296790_6 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000004365 66.0
HKD1_k127_4296790_7 nuclease activity - - - 0.00000000008998 67.0
HKD1_k127_4308539_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 416.0
HKD1_k127_4308539_1 cytochrome P450 K00493,K21257 - 1.14.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 417.0
HKD1_k127_4308539_2 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002925 278.0
HKD1_k127_4308539_3 PFAM glycoside hydrolase family 3 K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000002259 243.0
HKD1_k127_4308539_4 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000006587 131.0
HKD1_k127_4318614_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 336.0
HKD1_k127_4318614_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001145 287.0
HKD1_k127_4318614_2 Protein of unknown function (DUF3830) - - - 0.00000000000000000000000000000000000000000000000000000004858 201.0
HKD1_k127_4318614_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000000000003556 197.0
HKD1_k127_4318614_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000003745 131.0
HKD1_k127_4318614_5 - - - - 0.00000004498 60.0
HKD1_k127_4318924_0 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2141.0
HKD1_k127_4318924_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179 - 1.2.7.8 0.0 1290.0
HKD1_k127_4318924_10 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.477e-202 644.0
HKD1_k127_4318924_100 FCD K05799 - - 0.000000000000000000000000000000000000000000003003 175.0
HKD1_k127_4318924_101 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000002954 164.0
HKD1_k127_4318924_102 NUDIX domain - - - 0.0000000000000000000000000000000000000000003528 165.0
HKD1_k127_4318924_103 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000001016 164.0
HKD1_k127_4318924_104 Belongs to the ComB family K05979 - 3.1.3.71 0.00000000000000000000000000000000000001192 165.0
HKD1_k127_4318924_105 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000001874 156.0
HKD1_k127_4318924_107 dehydratase K17865 - 4.2.1.55 0.00000000000000000000000000000000006105 147.0
HKD1_k127_4318924_108 EamA-like transporter family - - - 0.0000000000000000000000000000000001488 145.0
HKD1_k127_4318924_11 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 611.0
HKD1_k127_4318924_110 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000001553 135.0
HKD1_k127_4318924_111 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.00000000000000000000000000000002795 134.0
HKD1_k127_4318924_112 Zn peptidase - - - 0.0000000000000000000000000000007674 140.0
HKD1_k127_4318924_113 Smr domain - - - 0.000000000000000000000000000005972 136.0
HKD1_k127_4318924_114 LUD domain K00782,K18929 - - 0.00000000000000000000000000007238 134.0
HKD1_k127_4318924_115 Belongs to the short-chain dehydrogenases reductases (SDR) family K04786,K13611,K13612,K13613,K13614,K16216 - 1.1.1.320 0.00000000000000000000000004277 121.0
HKD1_k127_4318924_116 PFAM PHA accumulation regulator DNA-binding protein - - - 0.000000000000000000000001697 111.0
HKD1_k127_4318924_117 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000006384 109.0
HKD1_k127_4318924_118 - - - - 0.000000000000000000003216 103.0
HKD1_k127_4318924_119 SCP-2 sterol transfer family - - - 0.00000000000000000002215 103.0
HKD1_k127_4318924_12 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 610.0
HKD1_k127_4318924_120 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000002198 95.0
HKD1_k127_4318924_121 member of haloacid dehalogenase (HAD)-like hydrolase superfamily K01560,K07025,K08723 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.5,3.8.1.2 0.00000000000000002251 92.0
HKD1_k127_4318924_122 Tetratricopeptide repeat - - - 0.0000000000000000247 93.0
HKD1_k127_4318924_123 EamA-like transporter family - - - 0.00000000000000006127 91.0
HKD1_k127_4318924_124 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000004922 88.0
HKD1_k127_4318924_125 polyhydroxyalkanoic acid synthase, PhaR subunit - - - 0.00000000002309 72.0
HKD1_k127_4318924_126 Protein of unknown function (DUF1285) K09986 - - 0.00000000005086 69.0
HKD1_k127_4318924_127 Protein of unknown function (DUF2889) - - - 0.0000000000807 74.0
HKD1_k127_4318924_128 - - - - 0.0000000005803 68.0
HKD1_k127_4318924_129 Methyltransferase domain K18896 - 2.1.1.156 0.0000002008 64.0
HKD1_k127_4318924_13 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 609.0
HKD1_k127_4318924_130 - - - - 0.0000004574 60.0
HKD1_k127_4318924_131 Zn-dependent protease - - - 0.0000005286 60.0
HKD1_k127_4318924_132 HEPN domain - - - 0.000255 47.0
HKD1_k127_4318924_133 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0004775 50.0
HKD1_k127_4318924_14 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 574.0
HKD1_k127_4318924_15 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 546.0
HKD1_k127_4318924_16 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 527.0
HKD1_k127_4318924_17 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 531.0
HKD1_k127_4318924_18 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 516.0
HKD1_k127_4318924_19 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 500.0
HKD1_k127_4318924_2 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1064.0
HKD1_k127_4318924_20 Domain of unknown function (DUF4445) K04755,K08952,K08953,K08954 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 507.0
HKD1_k127_4318924_21 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 505.0
HKD1_k127_4318924_22 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 485.0
HKD1_k127_4318924_23 PFAM extracellular solute-binding protein family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 502.0
HKD1_k127_4318924_24 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 458.0
HKD1_k127_4318924_25 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 459.0
HKD1_k127_4318924_26 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 466.0
HKD1_k127_4318924_27 LUD domain K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 467.0
HKD1_k127_4318924_28 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 445.0
HKD1_k127_4318924_29 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 451.0
HKD1_k127_4318924_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 8.56e-259 824.0
HKD1_k127_4318924_30 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 436.0
HKD1_k127_4318924_31 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 446.0
HKD1_k127_4318924_32 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 446.0
HKD1_k127_4318924_33 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 458.0
HKD1_k127_4318924_34 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 440.0
HKD1_k127_4318924_35 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 441.0
HKD1_k127_4318924_36 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 403.0
HKD1_k127_4318924_37 Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 404.0
HKD1_k127_4318924_38 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 406.0
HKD1_k127_4318924_39 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 415.0
HKD1_k127_4318924_4 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 1.794e-252 784.0
HKD1_k127_4318924_40 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 388.0
HKD1_k127_4318924_41 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 378.0
HKD1_k127_4318924_42 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 392.0
HKD1_k127_4318924_43 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 367.0
HKD1_k127_4318924_44 succinyl-diaminopimelate desuccinylase K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 355.0
HKD1_k127_4318924_45 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 346.0
HKD1_k127_4318924_46 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 345.0
HKD1_k127_4318924_47 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 344.0
HKD1_k127_4318924_48 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 345.0
HKD1_k127_4318924_49 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 344.0
HKD1_k127_4318924_5 Pyruvate flavodoxin ferredoxin K00174 - 1.2.7.11,1.2.7.3 1.335e-239 756.0
HKD1_k127_4318924_50 Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (PorD-like) K00171 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 329.0
HKD1_k127_4318924_51 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 326.0
HKD1_k127_4318924_52 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 326.0
HKD1_k127_4318924_53 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 302.0
HKD1_k127_4318924_54 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 300.0
HKD1_k127_4318924_55 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 301.0
HKD1_k127_4318924_56 PFAM binding-protein-dependent transport systems inner membrane component K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 292.0
HKD1_k127_4318924_57 peroxidase activity K00435 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 289.0
HKD1_k127_4318924_58 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001053 297.0
HKD1_k127_4318924_59 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001283 277.0
HKD1_k127_4318924_6 Tripartite tricarboxylate transporter TctA family K07793 - - 5.744e-236 747.0
HKD1_k127_4318924_60 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002043 288.0
HKD1_k127_4318924_61 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001455 286.0
HKD1_k127_4318924_62 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002978 288.0
HKD1_k127_4318924_63 COG0583 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001488 269.0
HKD1_k127_4318924_64 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000001232 261.0
HKD1_k127_4318924_65 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000005768 263.0
HKD1_k127_4318924_66 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006066 259.0
HKD1_k127_4318924_67 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002761 261.0
HKD1_k127_4318924_68 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009345 258.0
HKD1_k127_4318924_69 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006486 264.0
HKD1_k127_4318924_7 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 8.576e-212 694.0
HKD1_k127_4318924_70 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004459 252.0
HKD1_k127_4318924_71 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000009126 253.0
HKD1_k127_4318924_72 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001902 254.0
HKD1_k127_4318924_73 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005295 251.0
HKD1_k127_4318924_74 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000001063 258.0
HKD1_k127_4318924_75 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000001721 246.0
HKD1_k127_4318924_76 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000003999 259.0
HKD1_k127_4318924_77 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000002096 236.0
HKD1_k127_4318924_78 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000002668 249.0
HKD1_k127_4318924_79 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000008869 233.0
HKD1_k127_4318924_8 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 2.894e-211 674.0
HKD1_k127_4318924_80 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000422 241.0
HKD1_k127_4318924_81 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000004011 227.0
HKD1_k127_4318924_82 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K02302,K02303,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000003596 227.0
HKD1_k127_4318924_83 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000003712 225.0
HKD1_k127_4318924_84 Integral membrane protein TerC family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000001006 222.0
HKD1_k127_4318924_85 - - - - 0.0000000000000000000000000000000000000000000000000000000000001176 221.0
HKD1_k127_4318924_86 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000009419 220.0
HKD1_k127_4318924_87 Glucose dehydrogenase C-terminus K00001,K00344 - 1.1.1.1,1.6.5.5 0.000000000000000000000000000000000000000000000000000000000001253 223.0
HKD1_k127_4318924_88 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000003315 220.0
HKD1_k127_4318924_89 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000008439 220.0
HKD1_k127_4318924_9 4Fe-4S dicluster domain K00184 - - 9.659e-208 681.0
HKD1_k127_4318924_90 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000003751 205.0
HKD1_k127_4318924_91 COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000003038 205.0
HKD1_k127_4318924_92 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000002059 216.0
HKD1_k127_4318924_93 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000001908 205.0
HKD1_k127_4318924_94 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000003679 195.0
HKD1_k127_4318924_95 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000002925 192.0
HKD1_k127_4318924_96 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000004951 177.0
HKD1_k127_4318924_97 Pfam Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000008657 195.0
HKD1_k127_4318924_98 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000003654 177.0
HKD1_k127_4318924_99 PFAM regulatory protein TetR K13770 - - 0.000000000000000000000000000000000000000000002596 171.0
HKD1_k127_4342268_0 Periplasmic binding protein domain K01999 - - 3.111e-227 724.0
HKD1_k127_4342268_1 PFAM Glucose-inhibited division protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 476.0
HKD1_k127_4342268_10 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008361 260.0
HKD1_k127_4342268_11 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000001103 214.0
HKD1_k127_4342268_12 RESPONSE REGULATOR receiver - - - 0.00000000000000000000000000000000000000000001633 162.0
HKD1_k127_4342268_13 Binding-protein-dependent transport system inner membrane component K15554 - - 0.0000000000000000000000000002602 126.0
HKD1_k127_4342268_14 Binding-protein-dependent transport system inner membrane component K15552 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010438,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0042908,GO:0042910,GO:0042918,GO:0042959,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071496,GO:0071944 - 0.0000000000000000000000479 115.0
HKD1_k127_4342268_15 Roadblock/LC7 domain K07131 - - 0.0002592 49.0
HKD1_k127_4342268_16 Glycosyl transferase family 41 - - - 0.0007286 51.0
HKD1_k127_4342268_2 RESPONSE REGULATOR receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 445.0
HKD1_k127_4342268_3 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 432.0
HKD1_k127_4342268_4 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 432.0
HKD1_k127_4342268_5 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 378.0
HKD1_k127_4342268_6 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 368.0
HKD1_k127_4342268_7 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 314.0
HKD1_k127_4342268_8 Best Blastp hit gi 6685602 sp Q57957 KORB_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORB (2-KETOGLUTARATE OXIDOREDUCTASE BETA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE BETA SUBUNIT) gi 2129229 pir A64367 pyruvate synthase (EC 1.2.7.1) beta chain - Methanococcus jannaschii gi 1591241 gb AAB98531.1 '(U67503) 2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB) Methanococcus jannaschii ', score K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 287.0
HKD1_k127_4342268_9 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002778 294.0
HKD1_k127_4356737_0 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000005624 156.0
HKD1_k127_4356737_1 Putative esterase K07017 - - 0.00000000000000000000000000001179 122.0
HKD1_k127_4356737_2 ABC-type nitrate sulfonate bicarbonate transport system permease component K15554 - - 0.000000000000000000000000003084 124.0
HKD1_k127_4356737_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000005542 104.0
HKD1_k127_4356737_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000001585 92.0
HKD1_k127_4356737_5 PFAM ABC transporter related K01996 - - 0.00000000000000005249 82.0
HKD1_k127_4356737_6 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000004906 64.0
HKD1_k127_4356737_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000006023 54.0
HKD1_k127_4356737_8 Protein of unknown function (DUF3626) - - - 0.0000184 51.0
HKD1_k127_4383651_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 518.0
HKD1_k127_4383651_1 serine-type endopeptidase activity K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 309.0
HKD1_k127_4383651_2 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001711 306.0
HKD1_k127_4383651_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000002703 238.0
HKD1_k127_4383651_4 Arabinose efflux permease family protein - - - 0.00000000000000000000000000000000000000001271 169.0
HKD1_k127_4413916_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 397.0
HKD1_k127_4413916_1 NAD dependent epimerase/dehydratase family K07535 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001646 287.0
HKD1_k127_4413916_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004415 235.0
HKD1_k127_4455387_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1358.0
HKD1_k127_4455387_1 permease K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 387.0
HKD1_k127_4455387_2 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000003151 261.0
HKD1_k127_4455387_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000002316 222.0
HKD1_k127_4455387_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000006423 176.0
HKD1_k127_4457031_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 6.607e-227 712.0
HKD1_k127_4457031_1 Binding-protein-dependent transport system inner membrane component K02053,K02054 - - 6.11e-202 651.0
HKD1_k127_4457031_10 zinc ion binding K07048 GO:0008150,GO:0009888,GO:0009987,GO:0030154,GO:0030855,GO:0032502,GO:0048856,GO:0048869,GO:0060429 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 318.0
HKD1_k127_4457031_11 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 300.0
HKD1_k127_4457031_12 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006196 280.0
HKD1_k127_4457031_13 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000006511 235.0
HKD1_k127_4457031_14 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000001678 192.0
HKD1_k127_4457031_15 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000108 187.0
HKD1_k127_4457031_16 membrane transporter protein K07090 - - 0.0000000000000000000000000000005303 131.0
HKD1_k127_4457031_17 Transcription regulator K03718 - - 0.000000000000000000000002936 108.0
HKD1_k127_4457031_18 GYD domain - - - 0.00000000000000000000002722 104.0
HKD1_k127_4457031_19 nuclease - - - 0.0000000000000001894 81.0
HKD1_k127_4457031_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 491.0
HKD1_k127_4457031_20 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.000000000000001976 90.0
HKD1_k127_4457031_21 FAD binding domain K11472 - - 0.000000008634 58.0
HKD1_k127_4457031_23 - - - - 0.0001203 51.0
HKD1_k127_4457031_24 Fic/DOC family - - - 0.0005221 45.0
HKD1_k127_4457031_3 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 438.0
HKD1_k127_4457031_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 431.0
HKD1_k127_4457031_5 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 466.0
HKD1_k127_4457031_6 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 435.0
HKD1_k127_4457031_7 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 389.0
HKD1_k127_4457031_8 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 379.0
HKD1_k127_4457031_9 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 343.0
HKD1_k127_4465213_0 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 527.0
HKD1_k127_4465213_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 463.0
HKD1_k127_4465213_10 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000239 219.0
HKD1_k127_4465213_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000005568 203.0
HKD1_k127_4465213_12 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000001047 192.0
HKD1_k127_4465213_13 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000003482 188.0
HKD1_k127_4465213_15 Isochorismatase family K09020 - 3.5.1.110 0.0000000000000000000000000000000001256 142.0
HKD1_k127_4465213_16 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000003884 100.0
HKD1_k127_4465213_17 DNA-sulfur modification-associated - - - 0.000000000000000001433 98.0
HKD1_k127_4465213_18 DinB superfamily - - - 0.0000000000000004927 84.0
HKD1_k127_4465213_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 444.0
HKD1_k127_4465213_3 FAD dependent oxidoreductase K00244 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 415.0
HKD1_k127_4465213_4 Acyl- CoA dehydrogenase type 2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 370.0
HKD1_k127_4465213_5 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000215 287.0
HKD1_k127_4465213_6 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000005939 286.0
HKD1_k127_4465213_7 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000616 241.0
HKD1_k127_4465213_8 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000001679 243.0
HKD1_k127_4465213_9 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000000000000000000007181 212.0
HKD1_k127_4468102_0 Protein of unknown function (DUF3141) - - - 4.978e-315 981.0
HKD1_k127_4468102_1 UvrD/REP helicase N-terminal domain K03656,K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 4.044e-207 666.0
HKD1_k127_4468102_10 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.0000000000000000000000000000000000000000000001857 191.0
HKD1_k127_4468102_11 Protein export membrane protein K03296,K18138 - - 0.0000000000000000000000000000003449 140.0
HKD1_k127_4468102_12 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000002221 121.0
HKD1_k127_4468102_13 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000002172 110.0
HKD1_k127_4468102_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 3.881e-198 637.0
HKD1_k127_4468102_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 580.0
HKD1_k127_4468102_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 448.0
HKD1_k127_4468102_5 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 465.0
HKD1_k127_4468102_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 359.0
HKD1_k127_4468102_7 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 319.0
HKD1_k127_4468102_8 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003595 286.0
HKD1_k127_4468102_9 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000003332 218.0
HKD1_k127_4489601_0 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 405.0
HKD1_k127_4489601_1 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000001092 230.0
HKD1_k127_4489601_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000005289 214.0
HKD1_k127_4489601_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000007298 151.0
HKD1_k127_4489601_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000003533 148.0
HKD1_k127_4490697_0 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 400.0
HKD1_k127_4490697_1 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009857 267.0
HKD1_k127_4490697_2 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000004301 175.0
HKD1_k127_4490697_3 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000004001 141.0
HKD1_k127_4490697_4 penicillin-binding protein K05367 - 2.4.1.129 0.000000000000000000000000000000000001629 143.0
HKD1_k127_4495849_0 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 465.0
HKD1_k127_4495849_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 297.0
HKD1_k127_4495849_2 transport system permease K01998 - - 0.000000000000000000000000000000000000000000000000000008896 207.0
HKD1_k127_4495849_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000007367 154.0
HKD1_k127_4495849_4 response to pH - - - 0.00000005882 61.0
HKD1_k127_4531486_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.568e-280 880.0
HKD1_k127_4531486_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 9.531e-235 739.0
HKD1_k127_4531486_10 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000006319 123.0
HKD1_k127_4531486_11 Cellulose biosynthesis protein BcsS - - - 0.00002267 55.0
HKD1_k127_4531486_2 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 359.0
HKD1_k127_4531486_3 Asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 318.0
HKD1_k127_4531486_4 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 310.0
HKD1_k127_4531486_5 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 318.0
HKD1_k127_4531486_6 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009994 289.0
HKD1_k127_4531486_7 Belongs to the glycosyl hydrolase 26 family - - - 0.00000000000000000000000000000000000000000000000000000003451 218.0
HKD1_k127_4531486_8 2Fe-2S -binding domain protein - - - 0.000000000000000000000000000000000000000000000000000002188 199.0
HKD1_k127_4531486_9 KR domain K07535 - - 0.0000000000000000000000000000000000000000000001434 178.0
HKD1_k127_4542276_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.859e-316 974.0
HKD1_k127_4577840_0 4-hydroxyphenylacetate K00483 - 1.14.14.9 1.475e-246 769.0
HKD1_k127_4577840_1 Domain in cystathionine beta-synthase and other proteins. K14446 - 1.3.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 548.0
HKD1_k127_4577840_10 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000001641 218.0
HKD1_k127_4577840_11 PFAM aminoglycoside phosphotransferase K04343 - 2.7.1.72 0.00000000000000000000000000000000000000000000000000000002539 212.0
HKD1_k127_4577840_12 endonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000008769 205.0
HKD1_k127_4577840_13 acetyltransferase K19113 - - 0.00000000000000000000000000000000000000401 153.0
HKD1_k127_4577840_14 lactate metabolic process - - - 0.0000000000000000000000003727 117.0
HKD1_k127_4577840_15 OsmC-like protein - - - 0.00002828 52.0
HKD1_k127_4577840_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 504.0
HKD1_k127_4577840_3 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 489.0
HKD1_k127_4577840_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 452.0
HKD1_k127_4577840_5 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 403.0
HKD1_k127_4577840_6 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 335.0
HKD1_k127_4577840_7 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 333.0
HKD1_k127_4577840_8 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 314.0
HKD1_k127_4577840_9 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007391 271.0
HKD1_k127_4581761_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1259.0
HKD1_k127_4601901_0 xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 551.0
HKD1_k127_4601901_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 358.0
HKD1_k127_4601901_10 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0003341 44.0
HKD1_k127_4601901_2 Required for the activity of the bacterial periplasmic transport system of putrescine K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001093 273.0
HKD1_k127_4601901_3 ABC transporter (Permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003771 259.0
HKD1_k127_4601901_4 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000468 259.0
HKD1_k127_4601901_5 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000149 262.0
HKD1_k127_4601901_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000001713 186.0
HKD1_k127_4601901_8 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000006579 54.0
HKD1_k127_4601901_9 Mut7-C ubiquitin - - - 0.00004945 50.0
HKD1_k127_4630194_0 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 474.0
HKD1_k127_4630194_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 449.0
HKD1_k127_4630194_2 Hydrogenase expression formation protein (HypE) K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 337.0
HKD1_k127_4630194_3 Formiminotransferase domain, N-terminal subdomain K00603 - 2.1.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000173 280.0
HKD1_k127_4630194_4 Histidine kinase K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000002498 192.0
HKD1_k127_4630194_5 Short C-terminal domain K08982 - - 0.000000000628 66.0
HKD1_k127_4664408_0 Binding-protein-dependent transport system inner membrane component - - - 2.41e-215 683.0
HKD1_k127_4664408_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 502.0
HKD1_k127_4664408_10 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 299.0
HKD1_k127_4664408_11 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001681 289.0
HKD1_k127_4664408_12 phosphatidylinositol kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001929 249.0
HKD1_k127_4664408_13 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000008869 233.0
HKD1_k127_4664408_14 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000008497 229.0
HKD1_k127_4664408_15 COG2513 PEP phosphonomutase and related enzymes - - - 0.0000000000000000000000000000000000000000000000002068 187.0
HKD1_k127_4664408_16 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000003924 168.0
HKD1_k127_4664408_17 Demethylmenaquinone methyltransferase - - - 0.00000000000000000000000000000000001172 146.0
HKD1_k127_4664408_18 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000001189 141.0
HKD1_k127_4664408_19 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000001161 115.0
HKD1_k127_4664408_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 477.0
HKD1_k127_4664408_20 - - - - 0.00000000000000000000005407 104.0
HKD1_k127_4664408_21 DinB family - - - 0.000000000000003757 85.0
HKD1_k127_4664408_22 - - - - 0.000000008282 57.0
HKD1_k127_4664408_23 Tetratricopeptide repeat - - - 0.0003034 46.0
HKD1_k127_4664408_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 385.0
HKD1_k127_4664408_4 Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 366.0
HKD1_k127_4664408_5 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 345.0
HKD1_k127_4664408_6 serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 353.0
HKD1_k127_4664408_7 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 325.0
HKD1_k127_4664408_8 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 315.0
HKD1_k127_4664408_9 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 315.0
HKD1_k127_4675587_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 349.0
HKD1_k127_4675587_1 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000009065 194.0
HKD1_k127_4675587_2 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000001081 64.0
HKD1_k127_4701012_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006185 262.0
HKD1_k127_4701012_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000005037 218.0
HKD1_k127_4701012_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000002706 177.0
HKD1_k127_4701012_3 Branched-chain amino acid transport system / permease component - - - 0.000001619 54.0
HKD1_k127_4703857_0 FAD dependent oxidoreductase K13796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 581.0
HKD1_k127_4703857_1 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 467.0
HKD1_k127_4703857_10 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.00000000000000000000000000000000334 147.0
HKD1_k127_4703857_11 Serine aminopeptidase, S33 K06889,K07397 - - 0.00000000000000000000000003777 120.0
HKD1_k127_4703857_12 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000000000832 98.0
HKD1_k127_4703857_2 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 373.0
HKD1_k127_4703857_3 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 345.0
HKD1_k127_4703857_4 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 342.0
HKD1_k127_4703857_5 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004563 286.0
HKD1_k127_4703857_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000001172 234.0
HKD1_k127_4703857_7 domain protein K01992,K06994 - - 0.000000000000000000000000000000000000000000000000000000000000001511 230.0
HKD1_k127_4703857_8 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000000008067 216.0
HKD1_k127_4703857_9 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000004519 185.0
HKD1_k127_4776474_0 Helix-turn-helix domain K03088 - - 0.0000000000000000000000000002015 123.0
HKD1_k127_4776474_1 lysyltransferase activity K07027 - - 0.0000000001332 66.0
HKD1_k127_4776474_2 Domain of unknown function (DUF4349) - - - 0.00007821 51.0
HKD1_k127_47940_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1309.0
HKD1_k127_47940_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 2.524e-275 882.0
HKD1_k127_47940_10 ABC transporter substrate binding protein - - - 0.000000000000000000353 88.0
HKD1_k127_47940_11 PFAM MaoC domain protein dehydratase - - - 0.0000001174 57.0
HKD1_k127_47940_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 329.0
HKD1_k127_47940_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001793 259.0
HKD1_k127_47940_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000002033 246.0
HKD1_k127_47940_5 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000002568 240.0
HKD1_k127_47940_6 TIGR00255 family - - - 0.00000000000000000000000000000000000000000000000000000003189 208.0
HKD1_k127_47940_7 Orotidine 5'-phosphate decarboxylase / HUMPS family K13421 - 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000000000000000000000000603 196.0
HKD1_k127_47940_8 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000001071 169.0
HKD1_k127_47940_9 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000216 166.0
HKD1_k127_4898463_0 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 392.0
HKD1_k127_4898463_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596 - 4.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 389.0
HKD1_k127_4898463_10 ABC transporter, permease protein K02029,K10040,K16962 - - 0.0000000000000000000000000000000000000000000000000000000001084 211.0
HKD1_k127_4898463_11 Protein of unknown function (DUF917) K09703 - - 0.0000000000000000000000000000000000000000000000000000000001568 226.0
HKD1_k127_4898463_12 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000005948 208.0
HKD1_k127_4898463_13 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000000000000000000000000000001154 209.0
HKD1_k127_4898463_14 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.000000000000000000000000000000000000000000000000000006049 198.0
HKD1_k127_4898463_15 FCD - - - 0.00000000000000000000000003281 119.0
HKD1_k127_4898463_2 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 380.0
HKD1_k127_4898463_3 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 345.0
HKD1_k127_4898463_4 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 316.0
HKD1_k127_4898463_5 TIGRFAM peptidase T-like protein K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 302.0
HKD1_k127_4898463_6 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005044 268.0
HKD1_k127_4898463_7 membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001388 280.0
HKD1_k127_4898463_8 Protein of unknown function (DUF917) K09703 - - 0.0000000000000000000000000000000000000000000000000000000000000000002902 246.0
HKD1_k127_4898463_9 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000007452 220.0
HKD1_k127_4922003_0 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 293.0
HKD1_k127_4922003_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000006374 237.0
HKD1_k127_4922003_2 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000002874 226.0
HKD1_k127_4952397_0 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 559.0
HKD1_k127_4952397_1 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001044 265.0
HKD1_k127_5006100_0 PFAM Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 399.0
HKD1_k127_5006100_1 Transposase and inactivated derivatives - - - 0.0000000000000000000000000006551 117.0
HKD1_k127_5006100_2 DNA integration K03733 - - 0.0001551 51.0
HKD1_k127_500810_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 1.73e-254 801.0
HKD1_k127_500810_1 Belongs to the GcvT family K19191 - 1.5.3.19 6.553e-234 736.0
HKD1_k127_500810_2 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 464.0
HKD1_k127_500810_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.000000000000000000000000476 111.0
HKD1_k127_5038866_0 Domain of unknown function (DUF3394) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009856 562.0
HKD1_k127_5038866_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 546.0
HKD1_k127_5038866_10 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 375.0
HKD1_k127_5038866_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 372.0
HKD1_k127_5038866_12 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 336.0
HKD1_k127_5038866_13 PFAM ABC transporter related K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 309.0
HKD1_k127_5038866_14 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 303.0
HKD1_k127_5038866_15 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001056 275.0
HKD1_k127_5038866_16 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000006279 281.0
HKD1_k127_5038866_17 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - 0.000000000000000000000000000000000000000000000000000000000000000000000009693 248.0
HKD1_k127_5038866_18 PFAM Ornithine cyclodeaminase mu-crystallin K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000329 254.0
HKD1_k127_5038866_19 Iron-containing redox enzyme K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000005031 243.0
HKD1_k127_5038866_2 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 520.0
HKD1_k127_5038866_20 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000001764 235.0
HKD1_k127_5038866_21 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000003109 242.0
HKD1_k127_5038866_22 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000001393 224.0
HKD1_k127_5038866_23 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000005581 217.0
HKD1_k127_5038866_24 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000002951 194.0
HKD1_k127_5038866_25 Type II secretory pathway, component HofQ K02666 - - 0.0000000000000000000000000000000000000000000001799 193.0
HKD1_k127_5038866_26 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000001982 186.0
HKD1_k127_5038866_27 PFAM Pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000001638 170.0
HKD1_k127_5038866_28 General secretory system II, protein E domain protein K02652 - - 0.00000000000000000000000000000000000000001447 156.0
HKD1_k127_5038866_29 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000003712 139.0
HKD1_k127_5038866_3 phosphorelay signal transduction system K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 508.0
HKD1_k127_5038866_30 dehydratase - - - 0.0000000000000000000000000000005905 136.0
HKD1_k127_5038866_31 FCD - - - 0.0000000000000000000000000465 119.0
HKD1_k127_5038866_32 Glycosyl transferase, family 2 - - - 0.000000000000000000000005128 116.0
HKD1_k127_5038866_35 (Rieske (2Fe-2S) domain) K00363,K05710 - 1.7.1.15 0.000000000000000001716 96.0
HKD1_k127_5038866_36 COG3167 Tfp pilus assembly protein PilO K02664 - - 0.000000000000000004053 92.0
HKD1_k127_5038866_37 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000004976 94.0
HKD1_k127_5038866_38 Tetratricopeptide repeat - - - 0.000000000000002098 87.0
HKD1_k127_5038866_39 Prokaryotic N-terminal methylation motif K02650,K02655 - - 0.000000000000004217 83.0
HKD1_k127_5038866_4 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 477.0
HKD1_k127_5038866_40 Prokaryotic N-terminal methylation motif K02650,K02655 - - 0.00000000003364 69.0
HKD1_k127_5038866_42 4 iron, 4 sulfur cluster binding K00176,K00528,K03737,K20449 - 1.18.1.2,1.19.1.1,1.2.7.1,1.2.7.3,1.3.7.1 0.0000000004355 70.0
HKD1_k127_5038866_43 Pilus assembly protein, PilP K02665 - - 0.0000245 57.0
HKD1_k127_5038866_44 Putative Competence protein ComGF K02246,K02248 - - 0.0002371 53.0
HKD1_k127_5038866_45 Carboxypeptidase regulatory-like domain - - - 0.0002771 51.0
HKD1_k127_5038866_46 Type II transport protein GspH K08084 - - 0.0008058 52.0
HKD1_k127_5038866_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 438.0
HKD1_k127_5038866_6 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 441.0
HKD1_k127_5038866_7 branched-chain amino acid transport system, permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 451.0
HKD1_k127_5038866_8 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 434.0
HKD1_k127_5038866_9 GDP-mannose 4,6 dehydratase K01709 - 4.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 398.0
HKD1_k127_5038942_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 557.0
HKD1_k127_5038942_1 Acyclic terpene utilisation family protein AtuA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 493.0
HKD1_k127_5038942_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 494.0
HKD1_k127_5038942_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005639 286.0
HKD1_k127_5038942_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000003804 228.0
HKD1_k127_5038942_5 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000001123 213.0
HKD1_k127_5038942_6 Isochorismatase family K09020 - 3.5.1.110 0.00000000000000000000000000000000000000000000000000003116 202.0
HKD1_k127_5038942_7 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000000000000000006962 191.0
HKD1_k127_5038942_8 Domain of unknown function (DUF4387) - - - 0.00000000000000000000000000006333 130.0
HKD1_k127_5083061_0 PFAM sulfatase K01130 - 3.1.6.1 0.0 1040.0
HKD1_k127_5083061_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 527.0
HKD1_k127_5083061_2 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 418.0
HKD1_k127_5083061_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 347.0
HKD1_k127_5083061_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 289.0
HKD1_k127_5083061_5 MafB19-like deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000003301 246.0
HKD1_k127_5083061_6 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000001872 143.0
HKD1_k127_5083061_7 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000001296 98.0
HKD1_k127_5083061_8 Domain of unknown function (DUF4340) - - - 0.000000000000000001398 100.0
HKD1_k127_5108667_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 5.946e-218 696.0
HKD1_k127_5108667_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - - 4.368e-202 653.0
HKD1_k127_5108667_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 9.754e-202 643.0
HKD1_k127_5108667_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 369.0
HKD1_k127_5108667_4 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007617 276.0
HKD1_k127_5108667_5 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000002632 114.0
HKD1_k127_5108667_6 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000002153 81.0
HKD1_k127_5108667_7 toxin-antitoxin pair type II binding K08591,K19159 GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 0.0000000000002328 81.0
HKD1_k127_5118821_0 COG3209 Rhs family protein - - - 2.53e-319 1040.0
HKD1_k127_5118821_1 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005996 266.0
HKD1_k127_5118821_2 Clostripain family - - - 0.0000000000000000000000000000000000000000000000000000005843 211.0
HKD1_k127_5118821_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000002457 188.0
HKD1_k127_5118821_4 Kelch motif - - - 0.000000000000000000007715 110.0
HKD1_k127_5133290_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 599.0
HKD1_k127_5133290_1 transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 526.0
HKD1_k127_5133290_10 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000003891 251.0
HKD1_k127_5133290_11 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000006763 244.0
HKD1_k127_5133290_12 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000558 234.0
HKD1_k127_5133290_13 InterPro IPR008538 - - - 0.000000000000000000000000000000000000000000000001754 180.0
HKD1_k127_5133290_14 InterPro IPR008538 - - - 0.00000000000000000000000000000000000000000000003107 177.0
HKD1_k127_5133290_15 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000506 180.0
HKD1_k127_5133290_16 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.000000000000000000000000000000000000000000005095 172.0
HKD1_k127_5133290_17 Dihydroorotate dehydrogenase K00226 - 1.3.98.1 0.000000000000000000000000000000000000004597 166.0
HKD1_k127_5133290_18 AraC-like ligand binding domain - - - 0.0000000000000000000002193 103.0
HKD1_k127_5133290_19 Tautomerase enzyme - - - 0.00000000007072 65.0
HKD1_k127_5133290_2 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 418.0
HKD1_k127_5133290_3 Beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 372.0
HKD1_k127_5133290_4 Mandelate Racemase Muconate Lactonizing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 373.0
HKD1_k127_5133290_5 Methyltransferase small domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 314.0
HKD1_k127_5133290_6 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 317.0
HKD1_k127_5133290_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 289.0
HKD1_k127_5133290_8 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
HKD1_k127_5133290_9 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000152 274.0
HKD1_k127_5147581_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 6.919e-232 751.0
HKD1_k127_5147581_1 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 8.29e-212 673.0
HKD1_k127_5147581_10 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000009094 263.0
HKD1_k127_5147581_11 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000006371 261.0
HKD1_k127_5147581_12 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000006742 251.0
HKD1_k127_5147581_13 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000009211 204.0
HKD1_k127_5147581_14 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000001449 205.0
HKD1_k127_5147581_15 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000001497 187.0
HKD1_k127_5147581_16 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000002787 166.0
HKD1_k127_5147581_17 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000518 147.0
HKD1_k127_5147581_18 TIGRFAM RNA polymerase sigma factor RpoS K03087 - - 0.00000000000000000000000000000000005818 145.0
HKD1_k127_5147581_19 regulation of translation K05788 - - 0.000000000000000000000000000000007261 131.0
HKD1_k127_5147581_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 435.0
HKD1_k127_5147581_20 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000002347 138.0
HKD1_k127_5147581_21 Peptidase, M23 - - - 0.000000000000000000000000000001584 136.0
HKD1_k127_5147581_22 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000002146 123.0
HKD1_k127_5147581_23 Regulatory protein - - - 0.000000000000000000000008655 109.0
HKD1_k127_5147581_24 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000433 107.0
HKD1_k127_5147581_26 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000009346 93.0
HKD1_k127_5147581_27 Major facilitator Superfamily - - - 0.000008741 49.0
HKD1_k127_5147581_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 414.0
HKD1_k127_5147581_4 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 395.0
HKD1_k127_5147581_5 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 384.0
HKD1_k127_5147581_6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 395.0
HKD1_k127_5147581_7 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 381.0
HKD1_k127_5147581_8 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 383.0
HKD1_k127_5147581_9 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001058 268.0
HKD1_k127_5165176_0 PFAM magnesium chelatase K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 539.0
HKD1_k127_5165176_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000006142 175.0
HKD1_k127_5165176_2 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000000004294 166.0
HKD1_k127_5165176_3 PIN domain - - - 0.000000000000000000000000000000000000000004003 161.0
HKD1_k127_518732_0 ABC transporter - - - 1.062e-258 811.0
HKD1_k127_518732_1 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 301.0
HKD1_k127_518732_2 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000001081 197.0
HKD1_k127_518732_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000005974 175.0
HKD1_k127_518732_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000006352 91.0
HKD1_k127_5191246_0 TOBE domain K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 526.0
HKD1_k127_5191246_1 Acyl-CoA dehydrogenase, N-terminal domain K04117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 446.0
HKD1_k127_5191246_10 Copper binding periplasmic protein CusF K07152 - - 0.00002301 49.0
HKD1_k127_5191246_11 non-ribosomal peptide synthetase K16416 - - 0.00006235 51.0
HKD1_k127_5191246_12 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0009338 49.0
HKD1_k127_5191246_2 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 314.0
HKD1_k127_5191246_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 310.0
HKD1_k127_5191246_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000894 319.0
HKD1_k127_5191246_5 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 293.0
HKD1_k127_5191246_6 ABC transporter permease K17238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002676 247.0
HKD1_k127_5191246_7 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000001152 196.0
HKD1_k127_5191246_8 Phosphohistidine phosphatase, SixA K08296 - - 0.0000000004215 68.0
HKD1_k127_5191246_9 Cytochrome c K00406,K12263 - - 0.000000008375 62.0
HKD1_k127_5191694_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 504.0
HKD1_k127_5191694_1 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 490.0
HKD1_k127_5191694_10 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000009933 166.0
HKD1_k127_5191694_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 472.0
HKD1_k127_5191694_3 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 433.0
HKD1_k127_5191694_4 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 398.0
HKD1_k127_5191694_5 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 375.0
HKD1_k127_5191694_6 ABC-type transport system, periplasmic component surface lipoprotein K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 375.0
HKD1_k127_5191694_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 356.0
HKD1_k127_5191694_8 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 323.0
HKD1_k127_5191694_9 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 311.0
HKD1_k127_5199600_0 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 385.0
HKD1_k127_5199600_1 Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 371.0
HKD1_k127_5199600_2 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 348.0
HKD1_k127_5199600_3 Dehydrogenase E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 344.0
HKD1_k127_5199600_4 PFAM Transketolase K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 297.0
HKD1_k127_5199600_5 - - - - 0.00000000000000000000000000000000000000000000001052 189.0
HKD1_k127_5199600_6 Amidohydrolase family K01464 - 3.5.2.2 0.000000000000000003233 89.0
HKD1_k127_5199600_7 2Fe-2S -binding K03518,K07302 - 1.2.5.3,1.3.99.16 0.000000002859 69.0
HKD1_k127_5199600_8 Protein of unknown function (DUF402) K07586 - - 0.00000068 58.0
HKD1_k127_5238961_0 regulation of DNA-templated transcription, elongation - - - 2.658e-265 842.0
HKD1_k127_5238961_1 PFAM Carbohydrate-selective porin OprB K07267 - - 0.0000000000000000000000000000000000000000000000000000000000148 226.0
HKD1_k127_5238961_2 PIN domain - - - 0.000000000000000000000000002634 120.0
HKD1_k127_5238961_3 Predicted membrane protein (DUF2254) - - - 0.0000000000000000002291 92.0
HKD1_k127_5264865_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 428.0
HKD1_k127_5264865_1 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 344.0
HKD1_k127_5264865_2 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000001026 236.0
HKD1_k127_5264865_3 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000008225 208.0
HKD1_k127_5264865_4 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000003746 182.0
HKD1_k127_5264865_5 Involved in molybdopterin and thiamine biosynthesis, family 2 K03148,K21029,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.000000000000000000000000000002555 122.0
HKD1_k127_5264865_6 Helix-hairpin-helix motif - - - 0.0000000000000000000001149 102.0
HKD1_k127_5283606_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 1.209e-261 816.0
HKD1_k127_5283606_1 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 495.0
HKD1_k127_5283606_10 HRDC domain protein K03684 - 3.1.13.5 0.0001024 46.0
HKD1_k127_5283606_2 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 443.0
HKD1_k127_5283606_3 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 381.0
HKD1_k127_5283606_4 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 343.0
HKD1_k127_5283606_5 amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 344.0
HKD1_k127_5283606_6 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 316.0
HKD1_k127_5283606_7 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 313.0
HKD1_k127_5283606_8 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000008954 132.0
HKD1_k127_5283606_9 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000003328 58.0
HKD1_k127_5286462_0 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000002149 167.0
HKD1_k127_5286462_1 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000004029 127.0
HKD1_k127_5286462_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000005105 109.0
HKD1_k127_5289688_0 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 411.0
HKD1_k127_5289688_1 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009925 396.0
HKD1_k127_5289688_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 353.0
HKD1_k127_5289688_3 Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002104 263.0
HKD1_k127_5289688_4 Binding-protein-dependent transport system inner membrane component K11069,K11070 - - 0.0000000000000000000000000000000000000000000000000000007872 212.0
HKD1_k127_5289688_5 Putrescine transport system permease - - - 0.000000000000000000000000000000000000000000000115 191.0
HKD1_k127_5289688_6 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000001604 125.0
HKD1_k127_5289688_7 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000003986 129.0
HKD1_k127_5312571_0 sulfolactate sulfo-lyase activity K01685,K16849 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 571.0
HKD1_k127_5312571_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 445.0
HKD1_k127_5312571_2 acyl-CoA dehydrogenase activity K00248,K00253 - 1.3.8.1,1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 409.0
HKD1_k127_5312571_3 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.00000000000000000000000000000000000000000000000000001452 194.0
HKD1_k127_5312571_4 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000007599 167.0
HKD1_k127_5312571_5 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000001074 98.0
HKD1_k127_5312571_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.00000000000002278 76.0
HKD1_k127_5352312_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 440.0
HKD1_k127_5352312_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 443.0
HKD1_k127_5352312_2 PFAM Enoyl-CoA hydratase isomerase family K01715,K13767 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 301.0
HKD1_k127_5352312_3 PFAM transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000007997 125.0
HKD1_k127_5352312_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000212 114.0
HKD1_k127_5408106_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 8.862e-220 697.0
HKD1_k127_5408106_1 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities K00842,K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000009762 265.0
HKD1_k127_541256_0 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 421.0
HKD1_k127_541256_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003931 289.0
HKD1_k127_5453775_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 623.0
HKD1_k127_5453775_1 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 396.0
HKD1_k127_5453775_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000006314 219.0
HKD1_k127_5453775_3 Phosphoenolpyruvate hydrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000001428 218.0
HKD1_k127_5453775_4 SnoaL-like domain - - - 0.0000000000000000000003744 102.0
HKD1_k127_5454243_0 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004856 272.0
HKD1_k127_5454243_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000878 254.0
HKD1_k127_5454243_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000002589 256.0
HKD1_k127_5454243_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00009551 44.0
HKD1_k127_547913_0 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 589.0
HKD1_k127_547913_1 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 466.0
HKD1_k127_547913_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000001695 100.0
HKD1_k127_547913_3 Peptidase, M23 - - - 0.00000000000000001177 92.0
HKD1_k127_5534396_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 481.0
HKD1_k127_5534396_1 Squalene/phytoene synthase K00801,K02291,K10208 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 329.0
HKD1_k127_5534396_2 Belongs to the helicase family. UvrD subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001279 244.0
HKD1_k127_5534396_3 hydrolase (HAD superfamily) K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.00000000000000000000000000000000000000000000000009987 188.0
HKD1_k127_5534396_4 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000001224 170.0
HKD1_k127_5534396_5 - - - - 0.000000000000001799 89.0
HKD1_k127_5616124_0 Adenylate and Guanylate cyclase catalytic domain - - - 7.728e-291 933.0
HKD1_k127_5616124_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 4.567e-210 679.0
HKD1_k127_5616124_10 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 319.0
HKD1_k127_5616124_11 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000008005 211.0
HKD1_k127_5616124_12 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000007398 194.0
HKD1_k127_5616124_13 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000001024 205.0
HKD1_k127_5616124_14 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000009344 184.0
HKD1_k127_5616124_15 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000005971 181.0
HKD1_k127_5616124_16 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000009592 183.0
HKD1_k127_5616124_17 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000001255 136.0
HKD1_k127_5616124_18 PFAM cyclic nucleotide-binding K16922 - - 0.000000000000000000000000002997 126.0
HKD1_k127_5616124_19 glycosyl transferase family 8 - - - 0.00000000000000000000000003316 122.0
HKD1_k127_5616124_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.435e-199 639.0
HKD1_k127_5616124_20 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000000000003176 102.0
HKD1_k127_5616124_21 energy transducer activity K03832 - - 0.00000000000001655 84.0
HKD1_k127_5616124_22 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000002756 63.0
HKD1_k127_5616124_23 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000001732 60.0
HKD1_k127_5616124_24 - - - - 0.0000004417 62.0
HKD1_k127_5616124_3 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 617.0
HKD1_k127_5616124_4 TrkA-N domain K03455,K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 599.0
HKD1_k127_5616124_5 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 444.0
HKD1_k127_5616124_6 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 451.0
HKD1_k127_5616124_7 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 430.0
HKD1_k127_5616124_8 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 431.0
HKD1_k127_5616124_9 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 420.0
HKD1_k127_5619947_0 Cytochrome C and Quinol oxidase polypeptide I - - - 1.693e-257 805.0
HKD1_k127_5619947_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 614.0
HKD1_k127_5619947_10 Cytochrome c oxidase subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000007284 239.0
HKD1_k127_5619947_11 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000288 239.0
HKD1_k127_5619947_12 ABC transporter K01996,K11963 - - 0.00000000000000000000000000000000000000000000000000000000000002286 235.0
HKD1_k127_5619947_13 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000003456 207.0
HKD1_k127_5619947_14 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000004714 186.0
HKD1_k127_5619947_15 COG0666 FOG Ankyrin repeat - - - 0.000000000000000000000000000000000000000002921 163.0
HKD1_k127_5619947_16 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000003869 128.0
HKD1_k127_5619947_17 PIN domain - - - 0.0000000000000000001616 94.0
HKD1_k127_5619947_18 Predicted membrane protein (DUF2157) - - - 0.0000000000000000003777 98.0
HKD1_k127_5619947_19 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000001601 67.0
HKD1_k127_5619947_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 600.0
HKD1_k127_5619947_21 retrograde transport, endosome to plasma membrane K15502 - - 0.0000000016 64.0
HKD1_k127_5619947_22 methionine synthase K00549 - 2.1.1.14 0.000000003705 65.0
HKD1_k127_5619947_23 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000004824 56.0
HKD1_k127_5619947_25 - - - - 0.000735 52.0
HKD1_k127_5619947_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 460.0
HKD1_k127_5619947_4 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 331.0
HKD1_k127_5619947_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 315.0
HKD1_k127_5619947_6 Copper resistance protein D K07245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 298.0
HKD1_k127_5619947_7 Cytochrome C oxidase subunit II, periplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001563 255.0
HKD1_k127_5619947_8 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003318 256.0
HKD1_k127_5619947_9 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009326 243.0
HKD1_k127_563136_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0 1262.0
HKD1_k127_563136_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 8.091e-204 649.0
HKD1_k127_563136_10 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000001183 182.0
HKD1_k127_563136_11 HD domain - - - 0.000000000000000000000000000000000000000904 160.0
HKD1_k127_563136_12 PFAM MaoC like domain - - - 0.0000000000000000000000000000000001529 147.0
HKD1_k127_563136_13 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07226 - - 0.000000000000000000000000000004047 125.0
HKD1_k127_563136_14 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.000000000000000000000000000004441 120.0
HKD1_k127_563136_15 Periplasmic binding protein domain K01999 - - 0.0000000000359 74.0
HKD1_k127_563136_16 - - - - 0.000000002986 70.0
HKD1_k127_563136_2 L-carnitine dehydratase bile acid-inducible protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 495.0
HKD1_k127_563136_3 Belongs to the DapA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 450.0
HKD1_k127_563136_4 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 368.0
HKD1_k127_563136_5 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 336.0
HKD1_k127_563136_6 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001269 261.0
HKD1_k127_563136_7 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003788 272.0
HKD1_k127_563136_8 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000001473 213.0
HKD1_k127_563136_9 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.00000000000000000000000000000000000000000000000000000001528 211.0
HKD1_k127_566743_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 353.0
HKD1_k127_566743_1 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002417 271.0
HKD1_k127_566743_2 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000154 267.0
HKD1_k127_566743_3 Receptor family ligand binding region family protein 22 K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002642 265.0
HKD1_k127_566743_4 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002292 261.0
HKD1_k127_566743_5 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003642 268.0
HKD1_k127_566743_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000005663 193.0
HKD1_k127_5726640_0 Hydrolase CocE NonD family K06978 - - 4.456e-241 770.0
HKD1_k127_5726640_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 9.82e-222 713.0
HKD1_k127_5726640_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 385.0
HKD1_k127_5726640_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009217 250.0
HKD1_k127_5726640_4 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000004109 200.0
HKD1_k127_5726640_5 arylformamidase activity - - - 0.0000000000000000000000000000000000000000000000007116 186.0
HKD1_k127_5730449_0 Methionine synthase K00548 - 2.1.1.13 0.0 1372.0
HKD1_k127_5730449_1 Protein of unknown function, DUF255 K06888 - - 1.413e-256 815.0
HKD1_k127_5730449_10 Beta-eliminating lyase K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 369.0
HKD1_k127_5730449_11 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 367.0
HKD1_k127_5730449_12 Glycine D-amino acid oxidase (deaminating) K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001121 302.0
HKD1_k127_5730449_13 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001246 288.0
HKD1_k127_5730449_14 endonuclease III K00558,K01962,K01963,K03575 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.37,2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003854 272.0
HKD1_k127_5730449_15 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002311 255.0
HKD1_k127_5730449_16 racemase activity, acting on amino acids and derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000655 265.0
HKD1_k127_5730449_17 ABC transporter substrate-binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001763 255.0
HKD1_k127_5730449_18 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000003696 263.0
HKD1_k127_5730449_19 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000004885 233.0
HKD1_k127_5730449_2 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 4.947e-255 797.0
HKD1_k127_5730449_20 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000003493 224.0
HKD1_k127_5730449_21 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000003925 232.0
HKD1_k127_5730449_22 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000556 212.0
HKD1_k127_5730449_23 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.00000000000000000000000000000000000000000000000000000001656 216.0
HKD1_k127_5730449_24 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000003033 209.0
HKD1_k127_5730449_25 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000001439 214.0
HKD1_k127_5730449_26 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000007232 190.0
HKD1_k127_5730449_27 KR domain - - - 0.00000000000000000000000000000000000000000000004426 179.0
HKD1_k127_5730449_28 TIGRFAM sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family K13006,K19429 - - 0.00000000000000000000000000000000000000000002113 173.0
HKD1_k127_5730449_29 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000003702 169.0
HKD1_k127_5730449_3 Transketolase, pyrimidine binding domain K11381,K21416 - 1.2.4.4 4.45e-226 724.0
HKD1_k127_5730449_30 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000001143 152.0
HKD1_k127_5730449_31 xylanase chitin deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000002796 164.0
HKD1_k127_5730449_32 MaoC like domain - - - 0.000000000000000000000000000000000008915 141.0
HKD1_k127_5730449_33 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000002437 107.0
HKD1_k127_5730449_34 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000005112 106.0
HKD1_k127_5730449_35 With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate K03154 - - 0.000000000000001048 81.0
HKD1_k127_5730449_36 Glycosyl transferase, family 2 - - - 0.0000000003787 71.0
HKD1_k127_5730449_37 N-terminal half of MaoC dehydratase - - - 0.000000009629 63.0
HKD1_k127_5730449_38 Response regulator, receiver - - - 0.0001091 49.0
HKD1_k127_5730449_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 511.0
HKD1_k127_5730449_5 peptidase dimerisation domain protein K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 514.0
HKD1_k127_5730449_6 AMP-binding enzyme C-terminal domain K01897,K18660 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 481.0
HKD1_k127_5730449_7 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 438.0
HKD1_k127_5730449_8 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 415.0
HKD1_k127_5730449_9 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 374.0
HKD1_k127_5731861_0 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 526.0
HKD1_k127_5731861_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 442.0
HKD1_k127_5731861_10 branched-chain amino acid K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 289.0
HKD1_k127_5731861_11 Peptidase family C69 K14358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003125 291.0
HKD1_k127_5731861_12 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002737 290.0
HKD1_k127_5731861_13 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004354 284.0
HKD1_k127_5731861_14 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008579 280.0
HKD1_k127_5731861_15 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000001853 158.0
HKD1_k127_5731861_16 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000001934 152.0
HKD1_k127_5731861_17 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000003058 130.0
HKD1_k127_5731861_18 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000001783 123.0
HKD1_k127_5731861_19 Pfam:DUF955 - - - 0.000000000003714 67.0
HKD1_k127_5731861_2 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 465.0
HKD1_k127_5731861_20 Plasmid maintenance system killer protein K07334 - - 0.000000002693 62.0
HKD1_k127_5731861_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 403.0
HKD1_k127_5731861_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 409.0
HKD1_k127_5731861_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 347.0
HKD1_k127_5731861_6 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 337.0
HKD1_k127_5731861_7 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 342.0
HKD1_k127_5731861_8 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 336.0
HKD1_k127_5731861_9 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 304.0
HKD1_k127_5780303_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 550.0
HKD1_k127_5780303_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 500.0
HKD1_k127_5780303_2 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 445.0
HKD1_k127_5780303_3 CBS domain containing protein K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 364.0
HKD1_k127_5780303_4 DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001071 284.0
HKD1_k127_5780303_5 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000006029 77.0
HKD1_k127_5806927_0 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 497.0
HKD1_k127_5806927_1 Domain of unknown function (DUF4392) - - - 0.0000000000000000000000000000000000000000000000000007068 198.0
HKD1_k127_5809248_2 Transposase DDE domain - - - 0.0000000000000000000000000000003932 126.0
HKD1_k127_5849427_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 534.0
HKD1_k127_5849427_1 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 336.0
HKD1_k127_5849427_10 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000001296 171.0
HKD1_k127_5849427_11 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000009211 156.0
HKD1_k127_5849427_12 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000007626 133.0
HKD1_k127_5849427_13 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000004063 119.0
HKD1_k127_5849427_14 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000214 104.0
HKD1_k127_5849427_15 EamA-like transporter family - - - 0.00000000000008932 81.0
HKD1_k127_5849427_16 Transposase DDE domain group 1 - - - 0.000006948 58.0
HKD1_k127_5849427_2 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 308.0
HKD1_k127_5849427_3 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 302.0
HKD1_k127_5849427_4 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005917 275.0
HKD1_k127_5849427_5 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000007213 270.0
HKD1_k127_5849427_6 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009503 257.0
HKD1_k127_5849427_7 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000002063 259.0
HKD1_k127_5849427_8 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000378 250.0
HKD1_k127_5849427_9 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000623 240.0
HKD1_k127_584955_0 peptidase, M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 609.0
HKD1_k127_584955_1 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 383.0
HKD1_k127_584955_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 328.0
HKD1_k127_584955_3 PFAM SirA family protein - - - 0.00000000000004292 75.0
HKD1_k127_584955_4 - - - - 0.00000000003592 73.0
HKD1_k127_5853202_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 4.032e-316 981.0
HKD1_k127_5853202_1 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 407.0
HKD1_k127_5853202_2 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 346.0
HKD1_k127_5853202_3 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510,K12660 - 4.1.2.52,4.1.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 323.0
HKD1_k127_5853202_4 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 302.0
HKD1_k127_5853202_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004093 263.0
HKD1_k127_5853202_6 PFAM Integral membrane protein TerC K05794 - - 0.00000000005621 65.0
HKD1_k127_5853202_7 - - - - 0.0000003264 63.0
HKD1_k127_5853202_8 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.00002567 56.0
HKD1_k127_5861218_0 TRAP transporter, 4TM 12TM fusion protein - - - 1.531e-197 635.0
HKD1_k127_5861218_1 Protein of unknown function (DUF993) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 485.0
HKD1_k127_5861218_10 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000615 154.0
HKD1_k127_5861218_11 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000002016 114.0
HKD1_k127_5861218_12 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000002327 52.0
HKD1_k127_5861218_14 Evidence 4 Homologs of previously reported genes of - - - 0.000005305 53.0
HKD1_k127_5861218_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 473.0
HKD1_k127_5861218_3 Cysteine synthase B K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 401.0
HKD1_k127_5861218_4 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 394.0
HKD1_k127_5861218_5 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 347.0
HKD1_k127_5861218_6 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000009233 265.0
HKD1_k127_5861218_7 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000008541 241.0
HKD1_k127_5861218_8 Enoyl-CoA hydratase/isomerase - GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000003597 214.0
HKD1_k127_5861218_9 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000005464 141.0
HKD1_k127_5877507_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00928,K12524 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 512.0
HKD1_k127_5877507_1 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 372.0
HKD1_k127_5877507_2 Cobalamin-independent synthase, Catalytic domain K00549,K22363 - 2.1.1.14,4.4.1.23 0.0000197 50.0
HKD1_k127_5877910_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 516.0
HKD1_k127_5877910_1 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K15060 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 524.0
HKD1_k127_5877910_2 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000002184 211.0
HKD1_k127_5877910_3 - - - - 0.000000000000000000000000000000000000000152 164.0
HKD1_k127_589082_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 497.0
HKD1_k127_589082_1 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009652 272.0
HKD1_k127_589082_2 myo-inosose-2 dehydratase activity K00457,K06606 - 1.13.11.27,5.3.99.11 0.0000000000000000000000000000000000000000000000000000000000000000005099 241.0
HKD1_k127_589082_3 Pfam:DUF385 - - - 0.00000000000000001381 88.0
HKD1_k127_5990778_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 496.0
HKD1_k127_5990778_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001261 287.0
HKD1_k127_5990778_2 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001175 251.0
HKD1_k127_5990778_3 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000003036 215.0
HKD1_k127_5990778_4 - - - - 0.000000000000000000000000000000000000000005895 160.0
HKD1_k127_5990778_5 - - - - 0.0000000000000000000000000000000000031 140.0
HKD1_k127_5990778_6 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000001939 137.0
HKD1_k127_5990778_7 ABC transporter substrate binding protein K01989 - - 0.0000000000009782 75.0
HKD1_k127_5990778_8 Cytochrome p450 - - - 0.000000006634 59.0
HKD1_k127_6029079_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 488.0
HKD1_k127_6029079_1 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000000000000007167 181.0
HKD1_k127_6029079_2 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000028 115.0
HKD1_k127_6029079_3 Pilus assembly protein K02461,K02662,K02663,K12289 - - 0.000000000000000000002435 110.0
HKD1_k127_6029079_4 pilus assembly protein PilW K02459 - - 0.0000002415 63.0
HKD1_k127_6029079_5 type IV pilus modification protein PilV K02458 - - 0.00001433 52.0
HKD1_k127_6029079_6 TIGRFAM general secretion pathway protein H K02457 - - 0.0004327 49.0
HKD1_k127_6038056_0 xanthine dehydrogenase activity K03520 - 1.2.5.3 2.587e-317 998.0
HKD1_k127_6038056_1 DNA polymerase type-B family K02336 - 2.7.7.7 1.133e-225 722.0
HKD1_k127_6038056_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 362.0
HKD1_k127_6038056_11 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 366.0
HKD1_k127_6038056_12 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 371.0
HKD1_k127_6038056_13 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 340.0
HKD1_k127_6038056_14 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 335.0
HKD1_k127_6038056_15 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 332.0
HKD1_k127_6038056_16 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 334.0
HKD1_k127_6038056_17 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 333.0
HKD1_k127_6038056_18 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 306.0
HKD1_k127_6038056_19 NAD synthase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 299.0
HKD1_k127_6038056_2 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 617.0
HKD1_k127_6038056_20 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 301.0
HKD1_k127_6038056_21 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005477 285.0
HKD1_k127_6038056_22 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003208 298.0
HKD1_k127_6038056_23 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007865 267.0
HKD1_k127_6038056_24 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000004552 274.0
HKD1_k127_6038056_25 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.000000000000000000000000000000000000000000000000000000000000000000000012 255.0
HKD1_k127_6038056_26 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000005194 241.0
HKD1_k127_6038056_27 'Molybdopterin - - - 0.000000000000000000000000000000000000000000000000000000000005895 225.0
HKD1_k127_6038056_28 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000001216 166.0
HKD1_k127_6038056_29 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000004339 157.0
HKD1_k127_6038056_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 635.0
HKD1_k127_6038056_30 hydrolase - - - 0.000000000000000000000000000000000000002492 166.0
HKD1_k127_6038056_31 ThiS family K03636,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000003234 126.0
HKD1_k127_6038056_32 RNA recognition motif - - - 0.000000000000000000000000346 110.0
HKD1_k127_6038056_33 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000001228 99.0
HKD1_k127_6038056_34 DSBA-like thioredoxin domain - - - 0.000000000000000001123 93.0
HKD1_k127_6038056_35 RDD family - - - 0.00000000000004285 79.0
HKD1_k127_6038056_36 ribonuclease BN - - - 0.00000000002536 74.0
HKD1_k127_6038056_37 Domain of unknown function (DUF309) K09763 - - 0.0000002402 60.0
HKD1_k127_6038056_4 metallopeptidase activity K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007088 574.0
HKD1_k127_6038056_5 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 466.0
HKD1_k127_6038056_6 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 460.0
HKD1_k127_6038056_7 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 428.0
HKD1_k127_6038056_8 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 380.0
HKD1_k127_6038056_9 Associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 378.0
HKD1_k127_6077659_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001216 259.0
HKD1_k127_6077659_1 Endoribonuclease L-PSP K09021 - - 0.0000000000000000000000000000000000002123 146.0
HKD1_k127_6077659_2 PilT protein domain protein - - - 0.0000000000000000000000000003838 119.0
HKD1_k127_6077659_3 - - - - 0.00000007156 57.0
HKD1_k127_6093067_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0 1063.0
HKD1_k127_6093067_1 Alpha amylase, catalytic domain K06044 - 5.4.99.15 1.067e-310 982.0
HKD1_k127_6093067_10 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 331.0
HKD1_k127_6093067_11 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 318.0
HKD1_k127_6093067_12 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001468 263.0
HKD1_k127_6093067_13 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007308 259.0
HKD1_k127_6093067_14 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000001245 244.0
HKD1_k127_6093067_15 abc transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000004943 246.0
HKD1_k127_6093067_16 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000001772 231.0
HKD1_k127_6093067_17 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000007094 228.0
HKD1_k127_6093067_18 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000001764 195.0
HKD1_k127_6093067_19 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000000000000000001512 193.0
HKD1_k127_6093067_2 TIGRFAM malto-oligosyltrehalose trehalohydrolase K01236 - 3.2.1.141 1.578e-263 823.0
HKD1_k127_6093067_20 - - - - 0.0000000000000000000000000000000000000000000000001959 185.0
HKD1_k127_6093067_21 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K00697,K01087,K16055 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 0.000000000000000000000000000000008364 140.0
HKD1_k127_6093067_22 phosphorelay signal transduction system K07315 - 3.1.3.3 0.00000000000000000001297 106.0
HKD1_k127_6093067_23 Response regulator receiver - - - 0.000000000000000009795 89.0
HKD1_k127_6093067_24 Membrane - - - 0.00000000006813 74.0
HKD1_k127_6093067_26 COG2202 FOG PAS PAC domain - - - 0.00001881 53.0
HKD1_k127_6093067_3 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 1.346e-237 758.0
HKD1_k127_6093067_4 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 1.193e-231 741.0
HKD1_k127_6093067_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 527.0
HKD1_k127_6093067_6 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 533.0
HKD1_k127_6093067_7 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 519.0
HKD1_k127_6093067_8 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 499.0
HKD1_k127_6093067_9 glycogen (starch) synthase activity K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 383.0
HKD1_k127_6102820_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 479.0
HKD1_k127_6102820_1 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 393.0
HKD1_k127_6102820_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000001372 229.0
HKD1_k127_6102820_3 SNARE associated Golgi protein K03975 - - 0.000000000000006474 88.0
HKD1_k127_6102820_4 Peptidase s1 and s6 chymotrypsin hap K08372 - - 0.0000000000007504 81.0
HKD1_k127_6102820_5 PFAM Cyclic nucleotide-binding K03321,K10914 - - 0.000000000009643 71.0
HKD1_k127_6102820_6 - - - - 0.0004311 48.0
HKD1_k127_6130455_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 4.769e-198 630.0
HKD1_k127_6130455_1 Hydantoinase/oxoprolinase N-terminal region K01469,K01473 - 3.5.2.14,3.5.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 563.0
HKD1_k127_6130455_10 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000000000000000000000000000000000000000001218 179.0
HKD1_k127_6130455_11 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000001014 186.0
HKD1_k127_6130455_12 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000001411 175.0
HKD1_k127_6130455_13 metallopeptidase activity K06974 - - 0.0000000000000000000000000000000001023 146.0
HKD1_k127_6130455_14 Enoyl-CoA hydratase/isomerase - GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 - 0.000000000000000000000000000000001635 138.0
HKD1_k127_6130455_15 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000002988 89.0
HKD1_k127_6130455_16 Putative restriction endonuclease - - - 0.00000000000004248 79.0
HKD1_k127_6130455_17 ABC transporter substrate binding protein - - - 0.0000000000004063 70.0
HKD1_k127_6130455_18 glycine decarboxylation via glycine cleavage system K02437 - - 0.000000000003117 76.0
HKD1_k127_6130455_19 Glycine cleavage H-protein - - - 0.00000000005384 74.0
HKD1_k127_6130455_2 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 540.0
HKD1_k127_6130455_3 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 495.0
HKD1_k127_6130455_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 377.0
HKD1_k127_6130455_5 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 350.0
HKD1_k127_6130455_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 340.0
HKD1_k127_6130455_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 298.0
HKD1_k127_6130455_9 PIN domain - - - 0.0000000000000000000000000000000000000000000000000008403 190.0
HKD1_k127_6134394_0 Proline racemase K01777,K12658 - 5.1.1.4,5.1.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 547.0
HKD1_k127_6134394_1 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 447.0
HKD1_k127_6134394_10 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000009015 100.0
HKD1_k127_6134394_11 cytidylyl-transferase K00983,K21749 - 2.7.7.43,2.7.7.92 0.00000000000000886 86.0
HKD1_k127_6134394_12 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000032 84.0
HKD1_k127_6134394_13 - - - - 0.0000000001673 71.0
HKD1_k127_6134394_14 anaphase-promoting complex binding K20276 - - 0.000005058 57.0
HKD1_k127_6134394_2 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 420.0
HKD1_k127_6134394_3 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 372.0
HKD1_k127_6134394_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 361.0
HKD1_k127_6134394_5 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000004402 245.0
HKD1_k127_6134394_6 (ABC) transporter K02050 - - 0.0000000000000000000000000000000000000000000000000000004666 219.0
HKD1_k127_6134394_7 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000008161 166.0
HKD1_k127_6134394_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000002436 122.0
HKD1_k127_6134394_9 glycosyl transferase group 1 - - - 0.0000000000000000000001483 108.0
HKD1_k127_6147011_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 619.0
HKD1_k127_6147011_1 Oxidoreductase molybdopterin binding domain K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 473.0
HKD1_k127_6147011_10 Receptor family ligand binding region - - - 0.0000000000001102 75.0
HKD1_k127_6147011_11 Protein of unknown function (DUF2652) - - - 0.00000005348 61.0
HKD1_k127_6147011_12 PFAM RDD domain containing protein - - - 0.000001038 58.0
HKD1_k127_6147011_2 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 428.0
HKD1_k127_6147011_3 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 372.0
HKD1_k127_6147011_4 amino acid K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 331.0
HKD1_k127_6147011_5 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 314.0
HKD1_k127_6147011_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002596 295.0
HKD1_k127_6147011_7 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000226 247.0
HKD1_k127_6147011_8 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000115 188.0
HKD1_k127_6147011_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000006934 141.0
HKD1_k127_6170123_0 type VI secretion protein K11891 - - 0.0 1079.0
HKD1_k127_6170123_1 type VI secretion protein K11893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 531.0
HKD1_k127_6170123_2 TIGRFAM type IV VI secretion system protein, DotU family K11892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 430.0
HKD1_k127_6170123_3 TIGRFAM type VI secretion-associated protein, BMA_A0400 family K11890 - - 0.00000000000000000000000000000000000121 160.0
HKD1_k127_6170123_4 TIGRFAM type VI secretion lipoprotein, VC_A0113 family K11906 - - 0.00000000000000000000000000000144 126.0
HKD1_k127_6194252_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 362.0
HKD1_k127_6194252_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000003829 181.0
HKD1_k127_6212409_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1174.0
HKD1_k127_6212409_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 6.97e-241 762.0
HKD1_k127_6212409_10 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 392.0
HKD1_k127_6212409_11 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 371.0
HKD1_k127_6212409_12 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 343.0
HKD1_k127_6212409_13 quinone binding K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 329.0
HKD1_k127_6212409_14 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 292.0
HKD1_k127_6212409_15 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 294.0
HKD1_k127_6212409_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000006915 251.0
HKD1_k127_6212409_17 transport system periplasmic component K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004393 250.0
HKD1_k127_6212409_18 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000008868 221.0
HKD1_k127_6212409_19 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000003887 213.0
HKD1_k127_6212409_2 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 3.137e-235 744.0
HKD1_k127_6212409_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000001234 200.0
HKD1_k127_6212409_21 - - - - 0.000000000000000000000000000000000000000000000004668 178.0
HKD1_k127_6212409_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000002517 168.0
HKD1_k127_6212409_23 NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000004039 155.0
HKD1_k127_6212409_24 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000003632 124.0
HKD1_k127_6212409_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000007606 118.0
HKD1_k127_6212409_26 NMT1-like family - - - 0.00000000000000000000009907 104.0
HKD1_k127_6212409_27 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000001064 104.0
HKD1_k127_6212409_28 YtxH-like protein - - - 0.00000001645 60.0
HKD1_k127_6212409_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 471.0
HKD1_k127_6212409_4 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 458.0
HKD1_k127_6212409_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 448.0
HKD1_k127_6212409_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 446.0
HKD1_k127_6212409_7 catalyzes NAD -dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 445.0
HKD1_k127_6212409_8 Pyruvate dehydrogenase K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 400.0
HKD1_k127_6212409_9 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 379.0
HKD1_k127_6220790_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 2.48e-238 750.0
HKD1_k127_6220790_1 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 368.0
HKD1_k127_6220790_2 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 367.0
HKD1_k127_6220790_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000002529 276.0
HKD1_k127_6220790_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000003803 245.0
HKD1_k127_6220790_5 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000371 188.0
HKD1_k127_6220790_6 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000397 141.0
HKD1_k127_6220790_8 Belongs to the beta-ketoacyl-ACP synthases family K05551,K09458 - 2.3.1.179,2.3.1.235,2.3.1.260 0.00000000000002783 85.0
HKD1_k127_6220790_9 Phosphopantetheine attachment site - - - 0.00004554 52.0
HKD1_k127_624332_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 7.286e-222 723.0
HKD1_k127_624332_1 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 437.0
HKD1_k127_624332_10 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 0.00000000000001956 74.0
HKD1_k127_624332_11 - - - - 0.00000000001633 77.0
HKD1_k127_624332_12 - - - - 0.000000005409 69.0
HKD1_k127_624332_13 cAMP biosynthetic process - - - 0.000000129 61.0
HKD1_k127_624332_2 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 362.0
HKD1_k127_624332_3 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002168 295.0
HKD1_k127_624332_4 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000001459 237.0
HKD1_k127_624332_5 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000007433 192.0
HKD1_k127_624332_6 repeat-containing protein - - - 0.000000000000000005384 93.0
HKD1_k127_624332_7 Putative regulatory protein - - - 0.000000000000000167 86.0
HKD1_k127_624332_8 Evidence 5 No homology to any previously reported sequences K03765 - - 0.0000000000000007486 90.0
HKD1_k127_624332_9 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000001932 87.0
HKD1_k127_6244020_0 Proton-conducting membrane transporter K12137,K15828 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 608.0
HKD1_k127_6244020_1 NADH dehydrogenase (ubiquinone) activity K14089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 553.0
HKD1_k127_6244020_2 Proton-conducting membrane transporter K12141 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 421.0
HKD1_k127_6244020_3 NADH dehydrogenase K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 343.0
HKD1_k127_6244020_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000003124 232.0
HKD1_k127_6244020_5 Hydrogenase 4 membrane K12140 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000483 165.0
HKD1_k127_6244020_6 ArsR family transcriptional regulator - - - 0.000000000000000000000000000000248 127.0
HKD1_k127_6251829_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.492e-289 909.0
HKD1_k127_6251829_1 Psort location CytoplasmicMembrane, score 10.00 K03458 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 396.0
HKD1_k127_6251829_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 351.0
HKD1_k127_6251829_3 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 314.0
HKD1_k127_6251829_4 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000001616 175.0
HKD1_k127_6251829_5 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000001266 171.0
HKD1_k127_6251829_6 PFAM LemA K03744 - - 0.00000000000000000000000000000000000000006767 160.0
HKD1_k127_6251829_7 Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000002358 113.0
HKD1_k127_6256019_0 Adenylate and Guanylate cyclase catalytic domain - - - 1.5e-323 1026.0
HKD1_k127_6256019_1 Type VI secretion system, VipA, VC_A0107 or Hcp2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 350.0
HKD1_k127_6256019_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001372 296.0
HKD1_k127_6256019_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002021 244.0
HKD1_k127_6256019_4 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000002557 230.0
HKD1_k127_6256019_5 - - - - 0.000009042 55.0
HKD1_k127_6256019_6 Peptidoglycan-binding domain 1 protein - - - 0.0002535 50.0
HKD1_k127_6291120_0 Aconitase C-terminal domain K01681 - 4.2.1.3 5.732e-219 700.0
HKD1_k127_6291120_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009982 398.0
HKD1_k127_6291120_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 326.0
HKD1_k127_6291120_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006482 250.0
HKD1_k127_6291120_4 PrpF protein - - - 0.00000000000000000000000000000000000000000000000000001459 202.0
HKD1_k127_6291120_5 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.000000001752 59.0
HKD1_k127_6306088_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 481.0
HKD1_k127_6306088_1 Cupin - - - 0.0000007588 51.0
HKD1_k127_6316037_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000003375 100.0
HKD1_k127_6316037_1 to Mycodextranase precursor in Streptomyces sp. J-13-3 (Q93R89) - - - 0.000001494 62.0
HKD1_k127_6335554_0 Adenylate and Guanylate cyclase catalytic domain - - - 7.017e-226 714.0
HKD1_k127_6335554_1 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 582.0
HKD1_k127_6335554_10 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000005928 163.0
HKD1_k127_6335554_11 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000002399 176.0
HKD1_k127_6335554_12 Acyl-transferase K00655,K14598 - 2.3.1.51 0.00000000000000000000000000000000000001408 158.0
HKD1_k127_6335554_13 Transcription factor zinc-finger K09981 - - 0.000000000000006514 80.0
HKD1_k127_6335554_14 Bacterial regulatory protein, arsR family - - - 0.000000000001929 73.0
HKD1_k127_6335554_15 Putative transmembrane protein (PGPGW) - - - 0.0001238 49.0
HKD1_k127_6335554_2 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 572.0
HKD1_k127_6335554_3 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 546.0
HKD1_k127_6335554_4 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 410.0
HKD1_k127_6335554_5 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 388.0
HKD1_k127_6335554_6 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 326.0
HKD1_k127_6335554_7 PFAM SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000003454 201.0
HKD1_k127_6335554_8 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000007316 200.0
HKD1_k127_6335554_9 TIGRFAM DNA binding domain protein, excisionase family K22491 - - 0.0000000000000000000000000000000000000000000001475 182.0
HKD1_k127_6349600_0 Tripartite tricarboxylate transporter TctA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 529.0
HKD1_k127_6349600_1 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 512.0
HKD1_k127_6349600_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 362.0
HKD1_k127_6349600_3 Dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 350.0
HKD1_k127_6349600_4 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006189 287.0
HKD1_k127_6349600_5 4-carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000641 181.0
HKD1_k127_6349600_6 MaoC like domain K17865 - 4.2.1.55 0.00000000000000000000000000000000001271 144.0
HKD1_k127_6368680_0 PDGLE domain K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000001595 246.0
HKD1_k127_6368680_1 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000008291 83.0
HKD1_k127_6383403_0 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001866 274.0
HKD1_k127_6383403_1 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.00000000000000000000004964 102.0
HKD1_k127_6383403_2 - - - - 0.0000001807 55.0
HKD1_k127_6389251_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 1.259e-310 975.0
HKD1_k127_6389251_1 Fumarase C C-terminus K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 561.0
HKD1_k127_6389251_10 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000003902 260.0
HKD1_k127_6389251_11 Binding-protein-dependent transport system inner membrane component K02026,K10238 - - 0.0000000000000000000000000000000000000000000000000000000000000000002828 238.0
HKD1_k127_6389251_12 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000000000000000000000000001997 199.0
HKD1_k127_6389251_13 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000007521 175.0
HKD1_k127_6389251_14 HEPN domain - - - 0.000000000000000000000000000000003056 134.0
HKD1_k127_6389251_15 DoxX-like family - - - 0.0000000000000000000000000002692 120.0
HKD1_k127_6389251_16 serine-type endopeptidase activity K04772,K08372 - - 0.000000000000000000000000003632 124.0
HKD1_k127_6389251_17 Domain of unknown function (DUF4143) - - - 0.000000000000000000000003213 108.0
HKD1_k127_6389251_18 nucleotidyltransferase activity K07076 - - 0.000000000000000000001971 97.0
HKD1_k127_6389251_19 Amidase K01426 - 3.5.1.4 0.0000000000000000001408 90.0
HKD1_k127_6389251_2 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 496.0
HKD1_k127_6389251_20 - - - - 0.0001267 54.0
HKD1_k127_6389251_21 Protein of unknown function (DUF1207) - - - 0.0001483 48.0
HKD1_k127_6389251_3 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 496.0
HKD1_k127_6389251_4 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 452.0
HKD1_k127_6389251_5 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 348.0
HKD1_k127_6389251_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000938 281.0
HKD1_k127_6389251_7 transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001857 300.0
HKD1_k127_6389251_8 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008059 270.0
HKD1_k127_6389251_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000006424 252.0
HKD1_k127_6397598_0 indolepyruvate ferredoxin oxidoreductase activity K00175,K04090 - 1.2.7.11,1.2.7.3,1.2.7.8 0.0 1294.0
HKD1_k127_6397598_1 Histidine kinase K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 624.0
HKD1_k127_6397598_10 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 471.0
HKD1_k127_6397598_11 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007598 463.0
HKD1_k127_6397598_12 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 450.0
HKD1_k127_6397598_13 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 439.0
HKD1_k127_6397598_14 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 427.0
HKD1_k127_6397598_15 Aminotransferase class-V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 424.0
HKD1_k127_6397598_16 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 387.0
HKD1_k127_6397598_17 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 375.0
HKD1_k127_6397598_18 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 380.0
HKD1_k127_6397598_19 Histidyl-tRNA synthetase K00765,K01892,K02502 - 2.4.2.17,6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 381.0
HKD1_k127_6397598_2 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 561.0
HKD1_k127_6397598_20 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 368.0
HKD1_k127_6397598_21 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 359.0
HKD1_k127_6397598_22 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 362.0
HKD1_k127_6397598_23 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 373.0
HKD1_k127_6397598_24 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 357.0
HKD1_k127_6397598_25 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 371.0
HKD1_k127_6397598_26 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 352.0
HKD1_k127_6397598_27 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 339.0
HKD1_k127_6397598_28 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 334.0
HKD1_k127_6397598_29 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 296.0
HKD1_k127_6397598_3 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 575.0
HKD1_k127_6397598_30 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 296.0
HKD1_k127_6397598_31 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003551 279.0
HKD1_k127_6397598_32 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000004789 259.0
HKD1_k127_6397598_33 glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000001234 250.0
HKD1_k127_6397598_34 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000001526 221.0
HKD1_k127_6397598_35 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000002975 225.0
HKD1_k127_6397598_36 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000002663 218.0
HKD1_k127_6397598_37 - - - - 0.00000000000000000000000000000000000000000000000000000000004729 215.0
HKD1_k127_6397598_38 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000002534 203.0
HKD1_k127_6397598_39 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000001167 185.0
HKD1_k127_6397598_4 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 529.0
HKD1_k127_6397598_40 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000001088 173.0
HKD1_k127_6397598_41 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000003666 179.0
HKD1_k127_6397598_42 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.00000000000000000000000000000000000000329 153.0
HKD1_k127_6397598_43 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000004331 165.0
HKD1_k127_6397598_44 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000000000004496 153.0
HKD1_k127_6397598_45 Nitroreductase family - - - 0.000000000000000000000000000000001002 146.0
HKD1_k127_6397598_46 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000237 138.0
HKD1_k127_6397598_47 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000002877 122.0
HKD1_k127_6397598_48 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000003081 130.0
HKD1_k127_6397598_49 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000000000000006405 131.0
HKD1_k127_6397598_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 510.0
HKD1_k127_6397598_50 PFAM DivIVA family protein K04074 - - 0.00000000000000000000002137 105.0
HKD1_k127_6397598_51 YGGT family K02221 - - 0.00000000000000000000002415 105.0
HKD1_k127_6397598_52 DUF167 - - - 0.0000000000000000008978 89.0
HKD1_k127_6397598_53 Cell division protein FtsQ K03589 - - 0.00000000000000002226 93.0
HKD1_k127_6397598_54 Aspartyl protease - - - 0.000000000003405 71.0
HKD1_k127_6397598_55 pilus assembly protein PilW K02672 - - 0.0000000003376 68.0
HKD1_k127_6397598_56 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000009244 56.0
HKD1_k127_6397598_57 - - - - 0.0003431 49.0
HKD1_k127_6397598_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 500.0
HKD1_k127_6397598_7 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 480.0
HKD1_k127_6397598_8 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 475.0
HKD1_k127_6397598_9 Adenine deaminase C-terminal domain K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 471.0
HKD1_k127_6413011_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.58e-220 691.0
HKD1_k127_6413011_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 2.157e-197 629.0
HKD1_k127_6413011_10 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 305.0
HKD1_k127_6413011_11 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003544 271.0
HKD1_k127_6413011_12 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001165 286.0
HKD1_k127_6413011_13 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000001047 205.0
HKD1_k127_6413011_14 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000002864 185.0
HKD1_k127_6413011_15 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000005431 175.0
HKD1_k127_6413011_16 Protein of unknown function (DUF3225) - - - 0.0000000000000000000000000000000000000004349 158.0
HKD1_k127_6413011_17 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000000000000000000000000005564 158.0
HKD1_k127_6413011_18 regulation of translation K03530 - - 0.000000000000000000000000000000003941 133.0
HKD1_k127_6413011_19 HDOD domain - - - 0.0000000000000000000000000001483 130.0
HKD1_k127_6413011_2 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 604.0
HKD1_k127_6413011_20 EamA-like transporter family - - - 0.0000000000000000000000001212 119.0
HKD1_k127_6413011_21 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000475 105.0
HKD1_k127_6413011_22 Sulfurtransferase TusA - - - 0.000000000000000000003918 94.0
HKD1_k127_6413011_23 cheY-homologous receiver domain - - - 0.00000000001685 70.0
HKD1_k127_6413011_24 Protein of unknown function (DUF4089) - - - 0.000003356 51.0
HKD1_k127_6413011_3 PFAM Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 591.0
HKD1_k127_6413011_4 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 546.0
HKD1_k127_6413011_5 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 440.0
HKD1_k127_6413011_6 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 385.0
HKD1_k127_6413011_7 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 355.0
HKD1_k127_6413011_8 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 310.0
HKD1_k127_6413011_9 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 306.0
HKD1_k127_6415535_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 7.879e-252 789.0
HKD1_k127_6415535_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.391e-227 717.0
HKD1_k127_6415535_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000049 284.0
HKD1_k127_6415535_11 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002592 297.0
HKD1_k127_6415535_12 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006041 274.0
HKD1_k127_6415535_13 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003153 267.0
HKD1_k127_6415535_14 HrcA protein C terminal domain K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000989 238.0
HKD1_k127_6415535_15 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000003438 229.0
HKD1_k127_6415535_16 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000001464 181.0
HKD1_k127_6415535_17 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000002291 167.0
HKD1_k127_6415535_18 GrpE K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000004955 140.0
HKD1_k127_6415535_19 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000002189 136.0
HKD1_k127_6415535_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.132,1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 569.0
HKD1_k127_6415535_20 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000001686 123.0
HKD1_k127_6415535_21 Pfam:DUF385 - - - 0.00000000000007856 80.0
HKD1_k127_6415535_22 Trm112p-like protein K09791 - - 0.00000000718 68.0
HKD1_k127_6415535_23 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000001986 59.0
HKD1_k127_6415535_3 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 484.0
HKD1_k127_6415535_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 424.0
HKD1_k127_6415535_5 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 375.0
HKD1_k127_6415535_6 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 346.0
HKD1_k127_6415535_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 332.0
HKD1_k127_6415535_8 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 314.0
HKD1_k127_6415535_9 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 301.0
HKD1_k127_6421207_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1105.0
HKD1_k127_6421207_1 helicase activity - - - 0.0 1046.0
HKD1_k127_6421207_10 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000000000000000146 198.0
HKD1_k127_6421207_11 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000002882 186.0
HKD1_k127_6421207_12 DinB family - - - 0.00000000000000000000000000000000004882 147.0
HKD1_k127_6421207_13 TPM domain - - - 0.000000000000000000000000000000005929 133.0
HKD1_k127_6421207_14 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000006129 80.0
HKD1_k127_6421207_15 Unextendable partial coding region - - - 0.000000000003871 68.0
HKD1_k127_6421207_16 Amidohydrolase family - - - 0.00000002159 55.0
HKD1_k127_6421207_2 Hydantoinase/oxoprolinase - - - 8.614e-301 938.0
HKD1_k127_6421207_3 Hydantoinase B/oxoprolinase - - - 1.634e-274 877.0
HKD1_k127_6421207_4 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 602.0
HKD1_k127_6421207_5 PFAM aminotransferase class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 428.0
HKD1_k127_6421207_6 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 369.0
HKD1_k127_6421207_7 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 336.0
HKD1_k127_6421207_8 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002943 274.0
HKD1_k127_6421207_9 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000597 237.0
HKD1_k127_6457672_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 4.173e-219 698.0
HKD1_k127_6457672_1 III protein, CoA-transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 400.0
HKD1_k127_6457672_10 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000005656 127.0
HKD1_k127_6457672_11 Belongs to the HesB IscA family K13628,K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.000000000000000000000000001372 116.0
HKD1_k127_6457672_12 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.00000000004526 63.0
HKD1_k127_6457672_2 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000119 304.0
HKD1_k127_6457672_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001995 271.0
HKD1_k127_6457672_4 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000007102 228.0
HKD1_k127_6457672_5 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000007586 205.0
HKD1_k127_6457672_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000002483 196.0
HKD1_k127_6457672_7 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.0000000000000000000000000000000000000000000001255 192.0
HKD1_k127_6457672_8 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.0000000000000000000000000000000000000000007863 177.0
HKD1_k127_6457672_9 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000006986 149.0
HKD1_k127_6525340_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 5.31e-196 625.0
HKD1_k127_6525340_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 411.0
HKD1_k127_6525340_2 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 383.0
HKD1_k127_6525340_3 Alpha/beta hydrolase family - - - 0.00000000005237 72.0
HKD1_k127_654320_0 Major Facilitator Superfamily - - - 2.003e-202 637.0
HKD1_k127_654320_1 oxidoreductase - - - 0.000000000000006788 81.0
HKD1_k127_6553266_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 329.0
HKD1_k127_6553266_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000504 270.0
HKD1_k127_6553266_10 Outer membrane lipoprotein - - - 0.0000000000000000000000836 111.0
HKD1_k127_6553266_11 PFAM DNA methylase N-4 N-6 domain protein K00590 - 2.1.1.113 0.0000006957 60.0
HKD1_k127_6553266_12 Putative zinc-finger - - - 0.0000535 54.0
HKD1_k127_6553266_13 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0005763 52.0
HKD1_k127_6553266_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000004162 214.0
HKD1_k127_6553266_3 KR domain K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000001004 211.0
HKD1_k127_6553266_4 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000006077 186.0
HKD1_k127_6553266_5 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000001088 181.0
HKD1_k127_6553266_6 PFAM beta-lactamase domain protein K00784 - 3.1.26.11 0.000000000000000000000000000000000000001309 159.0
HKD1_k127_6553266_7 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000004363 148.0
HKD1_k127_6553266_8 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000005575 145.0
HKD1_k127_6553266_9 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.0000000000000000000000000000001552 129.0
HKD1_k127_6574059_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1023.0
HKD1_k127_6574059_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.495e-284 885.0
HKD1_k127_6574059_10 Formate/nitrite transporter K06212 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 321.0
HKD1_k127_6574059_11 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 293.0
HKD1_k127_6574059_12 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007025 280.0
HKD1_k127_6574059_13 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007554 250.0
HKD1_k127_6574059_14 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000474 259.0
HKD1_k127_6574059_15 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000709 248.0
HKD1_k127_6574059_16 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000985 192.0
HKD1_k127_6574059_17 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - 0.0000000000000000000000000000000000000004053 158.0
HKD1_k127_6574059_18 Putative nucleotide-binding of sugar-metabolising enzyme K21948,K22129 - 2.7.1.217,2.7.1.219,2.7.1.220 0.00000000000000000000000000000000004172 149.0
HKD1_k127_6574059_19 Thioredoxin-like - - - 0.000000000000000000000000000003785 128.0
HKD1_k127_6574059_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2e-254 800.0
HKD1_k127_6574059_20 Pup-like protein K13570 - - 0.00000000000001361 85.0
HKD1_k127_6574059_21 Nucleotidyltransferase domain - - - 0.000000000002005 74.0
HKD1_k127_6574059_22 Protein of unknown function DUF86 - - - 0.0000000003732 64.0
HKD1_k127_6574059_23 Putative regulatory protein - - - 0.00000001368 58.0
HKD1_k127_6574059_24 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0006472 48.0
HKD1_k127_6574059_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 507.0
HKD1_k127_6574059_4 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 467.0
HKD1_k127_6574059_5 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 464.0
HKD1_k127_6574059_6 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 449.0
HKD1_k127_6574059_7 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 392.0
HKD1_k127_6574059_8 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 364.0
HKD1_k127_6574059_9 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 344.0
HKD1_k127_6578532_0 Sodium calcium exchanger membrane K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008809 414.0
HKD1_k127_6578532_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 418.0
HKD1_k127_6578532_2 Possible lysine decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001372 288.0
HKD1_k127_6578532_3 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000002791 222.0
HKD1_k127_6578532_4 PFAM Ion transport 2 domain protein - - - 0.0000000000000000000000000000000000000000000002896 175.0
HKD1_k127_6578532_5 - - - - 0.00000000000000000001154 101.0
HKD1_k127_6578532_6 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000001872 67.0
HKD1_k127_6578532_7 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000002322 53.0
HKD1_k127_6581788_0 Belongs to the IlvD Edd family - - - 5.679e-214 692.0
HKD1_k127_6581788_1 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 565.0
HKD1_k127_6581788_10 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000181 278.0
HKD1_k127_6581788_11 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000645 289.0
HKD1_k127_6581788_12 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000001534 246.0
HKD1_k127_6581788_13 PEP-CTERM motif - - - 0.000000000000000000000000000000000000000000000000000000000000000004239 247.0
HKD1_k127_6581788_14 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000004652 243.0
HKD1_k127_6581788_15 Histidine kinase K07644 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000078 244.0
HKD1_k127_6581788_16 Transcriptional regulatory protein, C terminal K07665 - - 0.00000000000000000000000000000000000000000000000000000000000007068 222.0
HKD1_k127_6581788_17 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000008587 183.0
HKD1_k127_6581788_18 Part of a membrane complex involved in electron transport - - - 0.0000000000000000000000000000002156 141.0
HKD1_k127_6581788_19 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000005438 111.0
HKD1_k127_6581788_2 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 530.0
HKD1_k127_6581788_20 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000009847 110.0
HKD1_k127_6581788_21 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000005072 72.0
HKD1_k127_6581788_22 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000006786 78.0
HKD1_k127_6581788_23 Protein conserved in bacteria K09986 - - 0.000000006403 64.0
HKD1_k127_6581788_3 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 468.0
HKD1_k127_6581788_4 Fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 449.0
HKD1_k127_6581788_5 Part of a membrane complex involved in electron transport K03615 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 449.0
HKD1_k127_6581788_6 beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 402.0
HKD1_k127_6581788_7 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 406.0
HKD1_k127_6581788_8 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 385.0
HKD1_k127_6581788_9 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 332.0
HKD1_k127_661620_0 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 440.0
HKD1_k127_661620_1 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000444 287.0
HKD1_k127_661620_2 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000001146 198.0
HKD1_k127_661620_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000001434 195.0
HKD1_k127_661620_4 cellular response to DNA damage stimulus K07340 - - 0.0000000000000000000000000000000000000002708 153.0
HKD1_k127_661620_5 Transcriptional regulator K13641 - - 0.000000000000000000000000000000001454 141.0
HKD1_k127_661620_6 Glycosyl transferases group 1 - - - 0.000000000000000005202 97.0
HKD1_k127_6650643_0 amine oxidase - - - 1.382e-236 752.0
HKD1_k127_6650643_1 C4-dicarboxylate ABC transporter permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 477.0
HKD1_k127_6650643_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000004983 94.0
HKD1_k127_6650643_2 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 331.0
HKD1_k127_6650643_3 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 321.0
HKD1_k127_6650643_4 transporter solute receptor, DctP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 304.0
HKD1_k127_6650643_5 COG3639 ABC-type phosphate phosphonate transport system, permease component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002314 292.0
HKD1_k127_6650643_6 COG3639 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001234 271.0
HKD1_k127_6650643_7 WHG domain - - - 0.00000000000000000000000000000000000000000003336 169.0
HKD1_k127_6650643_8 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000009823 110.0
HKD1_k127_6650643_9 Belongs to the ompA family K03286 - - 0.000000000000000000001854 106.0
HKD1_k127_6675263_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 552.0
HKD1_k127_6675263_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 393.0
HKD1_k127_6675263_2 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 402.0
HKD1_k127_6675263_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 333.0
HKD1_k127_6675263_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001912 286.0
HKD1_k127_6675263_5 radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000002964 179.0
HKD1_k127_6675263_6 glycosyl transferase family 2 - - - 0.00000000000000000000000000000003237 141.0
HKD1_k127_6675263_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000004705 104.0
HKD1_k127_6675263_8 Tetratricopeptide repeat - - - 0.000000000000000000194 102.0
HKD1_k127_6675263_9 Universal stress protein family - - - 0.000003473 57.0
HKD1_k127_670575_0 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 335.0
HKD1_k127_670575_1 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009382 256.0
HKD1_k127_670575_2 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000003118 158.0
HKD1_k127_670575_3 DinB superfamily - - - 0.000000000000000000000000001273 124.0
HKD1_k127_6722968_0 PFAM carboxyl transferase K01615 - 4.1.1.70 2.306e-281 875.0
HKD1_k127_6722968_1 Selenium-binding protein K17285 - - 1.012e-220 691.0
HKD1_k127_6722968_2 acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 560.0
HKD1_k127_6722968_3 Di-haem cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 470.0
HKD1_k127_6722968_4 Psort location CytoplasmicMembrane, score 10.00 K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 383.0
HKD1_k127_6722968_5 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 311.0
HKD1_k127_6722968_6 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000006194 218.0
HKD1_k127_6722968_7 catechol 2,3-dioxygenase activity K07104 - 1.13.11.2 0.00000000000000000000002537 112.0
HKD1_k127_6722968_8 PFAM Xanthine uracil vitamin C permease K06901 - - 0.000000000000000001584 89.0
HKD1_k127_6722968_9 Biotin-requiring enzyme - - - 0.000000001164 63.0
HKD1_k127_6743537_0 Carboxyl transferase domain - - - 1.319e-245 767.0
HKD1_k127_6743537_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000006389 226.0
HKD1_k127_6743537_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000005969 174.0
HKD1_k127_6743537_3 very-long-chain-acyl-CoA dehydrogenase activity K00249,K11729 GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0031974,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.8.7 0.000000000000000000000000000000000000000004111 163.0
HKD1_k127_6743537_4 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.00000000000000000000000006705 113.0
HKD1_k127_6756011_0 formate dehydrogenase (NAD+) activity K00123,K05299 - 1.17.1.10,1.17.1.9 1.049e-235 762.0
HKD1_k127_6756011_1 Beta-lactamase - - - 3.295e-204 661.0
HKD1_k127_6756011_10 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000001811 170.0
HKD1_k127_6756011_11 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000003561 148.0
HKD1_k127_6756011_12 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000009243 145.0
HKD1_k127_6756011_13 Predicted permease - - - 0.000000000000000000000000008043 123.0
HKD1_k127_6756011_14 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000007142 101.0
HKD1_k127_6756011_15 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000004806 89.0
HKD1_k127_6756011_2 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 617.0
HKD1_k127_6756011_3 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 382.0
HKD1_k127_6756011_4 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 382.0
HKD1_k127_6756011_5 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 316.0
HKD1_k127_6756011_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 313.0
HKD1_k127_6756011_7 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 288.0
HKD1_k127_6756011_8 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002476 262.0
HKD1_k127_6756011_9 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000007087 219.0
HKD1_k127_6762008_0 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 614.0
HKD1_k127_6762008_1 Circularly permuted ATP-grasp type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 549.0
HKD1_k127_6762008_10 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000001396 148.0
HKD1_k127_6762008_11 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000007493 142.0
HKD1_k127_6762008_12 Thioesterase family - - - 0.000000000000000000000000000000009319 131.0
HKD1_k127_6762008_13 protein conserved in bacteria - - - 0.000000000000000000000000000001458 140.0
HKD1_k127_6762008_14 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000008327 107.0
HKD1_k127_6762008_15 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000007665 111.0
HKD1_k127_6762008_16 Beta-lactamase - - - 0.00000000000000007786 89.0
HKD1_k127_6762008_17 - - - - 0.00000000001512 67.0
HKD1_k127_6762008_18 - - - - 0.00000000006578 66.0
HKD1_k127_6762008_19 OsmC-like protein - - - 0.0000002343 56.0
HKD1_k127_6762008_2 Peptidase dimerisation domain K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 417.0
HKD1_k127_6762008_20 - - - - 0.00001448 49.0
HKD1_k127_6762008_3 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 300.0
HKD1_k127_6762008_4 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009032 273.0
HKD1_k127_6762008_5 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000373 233.0
HKD1_k127_6762008_6 transglutaminase-like - - - 0.0000000000000000000000000000000000000000000000000000001227 210.0
HKD1_k127_6762008_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000004353 178.0
HKD1_k127_6762008_8 NUDIX domain K00077,K01092,K03574,K03795 - 1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3 0.000000000000000000000000000000000000000000104 165.0
HKD1_k127_6762008_9 response to heat K07090 - - 0.000000000000000000000000000000000000000000168 168.0
HKD1_k127_6774754_0 Hydantoinaseoxoprolinase domain protein K01469,K01473 - 3.5.2.14,3.5.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 338.0
HKD1_k127_6774754_1 TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 306.0
HKD1_k127_6774754_2 PFAM ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000006403 239.0
HKD1_k127_6774754_3 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.00000000000000000000000000000000000000000000000000000002579 211.0
HKD1_k127_6774754_4 cheY-homologous receiver domain - - - 0.000000000000000000000000000002878 131.0
HKD1_k127_6774754_5 Roadblock/LC7 domain - - - 0.000000000000000000000000006027 116.0
HKD1_k127_6774754_7 Transcriptional regulatory protein, C terminal K02483,K07667 GO:0008150,GO:0040007 - 0.00001606 56.0
HKD1_k127_6794933_0 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 360.0
HKD1_k127_6794933_1 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001023 275.0
HKD1_k127_6794933_2 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000001222 237.0
HKD1_k127_6794933_3 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000009303 233.0
HKD1_k127_6794933_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000474 201.0
HKD1_k127_6794933_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000826 152.0
HKD1_k127_6794933_6 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000001008 108.0
HKD1_k127_6797663_0 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 377.0
HKD1_k127_6797663_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 361.0
HKD1_k127_6797663_10 - K16937 - 1.8.5.2 0.000000000000000000000000000000000000004813 168.0
HKD1_k127_6797663_11 Thioredoxin - - - 0.00000000000000000000000000000000003473 138.0
HKD1_k127_6797663_12 PFAM Lipid A Biosynthesis N-terminal - - - 0.000000000000000000000000000000002828 132.0
HKD1_k127_6797663_13 COG3806 Anti-sigma factor - - - 0.00000000000000000002643 96.0
HKD1_k127_6797663_14 Belongs to the UPF0337 (CsbD) family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000001307 90.0
HKD1_k127_6797663_15 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000005563 96.0
HKD1_k127_6797663_16 - - - - 0.0000000000000009461 80.0
HKD1_k127_6797663_17 Protein of unknown function (DUF1328) - - - 0.000000000007864 73.0
HKD1_k127_6797663_2 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 347.0
HKD1_k127_6797663_3 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001294 265.0
HKD1_k127_6797663_4 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000007725 240.0
HKD1_k127_6797663_5 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000009833 209.0
HKD1_k127_6797663_6 NAD binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000006802 214.0
HKD1_k127_6797663_7 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000002534 213.0
HKD1_k127_6797663_8 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000003002 181.0
HKD1_k127_6797663_9 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000001484 164.0
HKD1_k127_6799058_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 366.0
HKD1_k127_6799058_1 Poly A polymerase head domain K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000003684 226.0
HKD1_k127_6816688_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 482.0
HKD1_k127_6816688_1 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001196 262.0
HKD1_k127_6816688_2 transport system periplasmic component K21395 - - 0.000000000000000000000000000000000000000000243 173.0
HKD1_k127_6816688_3 Major facilitator superfamily - - - 0.000000000000000000000000000000000004577 154.0
HKD1_k127_6816688_4 Thioredoxin - - - 0.0000000000000000000000004644 114.0
HKD1_k127_6816688_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000008273 94.0
HKD1_k127_6816688_6 FAD dependent oxidoreductase - - - 0.00000000000002549 78.0
HKD1_k127_6816688_7 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000002628 78.0
HKD1_k127_6853956_0 Glycogen debranching enzyme - - - 3.121e-293 910.0
HKD1_k127_6853956_1 alpha amylase, catalytic region - - - 2.228e-212 677.0
HKD1_k127_6853956_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 463.0
HKD1_k127_6853956_3 - - - - 0.000000000000000000000000000000000000000002995 177.0
HKD1_k127_6853956_4 cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000007948 168.0
HKD1_k127_6853956_5 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000001823 148.0
HKD1_k127_6853956_6 rRNA (guanine-N2-)-methyltransferase activity - - - 0.000000000000000000002068 102.0
HKD1_k127_6853956_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000002273 78.0
HKD1_k127_6853956_8 lyase activity - - - 0.000002517 61.0
HKD1_k127_6858188_0 Heat shock 70 kDa protein K04043 - - 6.551e-292 907.0
HKD1_k127_6858188_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.225e-288 906.0
HKD1_k127_6858188_2 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000003235 284.0
HKD1_k127_6858188_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001087 253.0
HKD1_k127_6858188_4 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.00000000000000000000000000000000000000000000000000000000002192 213.0
HKD1_k127_6858188_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000009664 150.0
HKD1_k127_6858188_6 C-terminal domain of histone - - - 0.00000000000000000000000000000000000001312 160.0
HKD1_k127_6858188_7 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000001751 124.0
HKD1_k127_6858188_8 Domain of unknown function (DUF1844) - - - 0.0000000001135 74.0
HKD1_k127_6873573_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.001e-245 778.0
HKD1_k127_6873573_1 Carboxyl transferase domain - - - 3.086e-213 673.0
HKD1_k127_6873573_10 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 407.0
HKD1_k127_6873573_11 Chalcone and stilbene synthases, C-terminal domain K16424 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.246 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 401.0
HKD1_k127_6873573_12 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 395.0
HKD1_k127_6873573_13 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 388.0
HKD1_k127_6873573_14 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 387.0
HKD1_k127_6873573_15 Sigma-70 factor, region 1.1 K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 372.0
HKD1_k127_6873573_16 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 361.0
HKD1_k127_6873573_17 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 357.0
HKD1_k127_6873573_18 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 339.0
HKD1_k127_6873573_19 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 338.0
HKD1_k127_6873573_2 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 1.271e-206 662.0
HKD1_k127_6873573_20 TIGRFAM amidase, hydantoinase carbamoylase K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 328.0
HKD1_k127_6873573_21 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 313.0
HKD1_k127_6873573_22 PFAM molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 299.0
HKD1_k127_6873573_23 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 289.0
HKD1_k127_6873573_24 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002777 307.0
HKD1_k127_6873573_25 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002785 284.0
HKD1_k127_6873573_26 pfam abc K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007019 280.0
HKD1_k127_6873573_27 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000111 287.0
HKD1_k127_6873573_28 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009434 289.0
HKD1_k127_6873573_29 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004109 285.0
HKD1_k127_6873573_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 595.0
HKD1_k127_6873573_30 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000008292 256.0
HKD1_k127_6873573_31 Bacterial transferase hexapeptide (six repeats) - GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043168,GO:0043169,GO:0043199,GO:0046872,GO:0046914,GO:0050897,GO:0071890,GO:1901681 - 0.000000000000000000000000000000000000000000000000000000000000000001983 235.0
HKD1_k127_6873573_32 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000001964 243.0
HKD1_k127_6873573_33 COGs COG1845 Heme copper-type cytochrome quinol oxidase subunit 3 K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000002577 233.0
HKD1_k127_6873573_34 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000007073 227.0
HKD1_k127_6873573_35 Glucose inhibited division protein A K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000266 237.0
HKD1_k127_6873573_36 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000003104 239.0
HKD1_k127_6873573_37 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000126 198.0
HKD1_k127_6873573_38 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000001704 211.0
HKD1_k127_6873573_39 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000004932 201.0
HKD1_k127_6873573_4 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 593.0
HKD1_k127_6873573_40 ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000001318 199.0
HKD1_k127_6873573_41 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.00000000000000000000000000000000000000000000000007639 198.0
HKD1_k127_6873573_42 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 0.00000000000000000000000000000000000000000000006942 185.0
HKD1_k127_6873573_43 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000001064 168.0
HKD1_k127_6873573_44 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000004523 146.0
HKD1_k127_6873573_45 bis(5'-adenosyl)-triphosphatase activity - - - 0.00000000000000000000000000000000002375 153.0
HKD1_k127_6873573_46 DinB family - - - 0.0000000000000000000000000000000002475 138.0
HKD1_k127_6873573_47 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219,K01069 - 1.3.1.34,3.1.2.6 0.0000000000000000000000000000002762 136.0
HKD1_k127_6873573_48 Biotin-lipoyl like - - - 0.00000000000000001497 85.0
HKD1_k127_6873573_49 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000003413 70.0
HKD1_k127_6873573_5 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 494.0
HKD1_k127_6873573_50 YceI-like domain - - - 0.00000000003641 72.0
HKD1_k127_6873573_51 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.0001108 53.0
HKD1_k127_6873573_6 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 497.0
HKD1_k127_6873573_7 Amidohydrolase family K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 427.0
HKD1_k127_6873573_8 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 418.0
HKD1_k127_6873573_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 435.0
HKD1_k127_6881541_0 Amidase - - - 1.081e-195 621.0
HKD1_k127_6881541_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 415.0
HKD1_k127_6881541_2 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 314.0
HKD1_k127_6881541_3 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000732 224.0
HKD1_k127_6881541_4 COG2199 FOG GGDEF domain - - - 0.0000000000000000000000000000000000009132 154.0
HKD1_k127_6881541_5 RNA recognition motif - - - 0.000000000000000000000002587 106.0
HKD1_k127_6881541_6 B12 binding domain K01849 - 5.4.99.2 0.000000000000000003167 90.0
HKD1_k127_6881541_7 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000004289 63.0
HKD1_k127_6881541_8 PIN domain - - - 0.0004101 50.0
HKD1_k127_6934525_0 NADH-quinone oxidoreductase chain L K00341,K05577 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 506.0
HKD1_k127_6934525_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.000000000000000000000000000008451 125.0
HKD1_k127_6934525_2 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.000000000000000001224 94.0
HKD1_k127_6934525_3 4Fe-4S dicluster domain K00338,K02573,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3,1.6.99.3 0.000000009988 59.0
HKD1_k127_6945851_0 Xanthine dehydrogenase K03520 - 1.2.5.3 2.533e-284 895.0
HKD1_k127_6945851_1 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 349.0
HKD1_k127_6945851_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 293.0
HKD1_k127_6945851_3 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008656 270.0
HKD1_k127_6945851_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004159 289.0
HKD1_k127_6945851_5 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001568 254.0
HKD1_k127_6945851_6 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000001197 227.0
HKD1_k127_6945851_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000003788 233.0
HKD1_k127_6945851_8 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000001123 198.0
HKD1_k127_6945851_9 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000002735 145.0
HKD1_k127_6977207_0 CDP-diacylglycerol pyrophosphatase K01521 - 3.6.1.26 0.000000000000000000000000000000000000000000001257 174.0
HKD1_k127_6977207_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000005941 160.0
HKD1_k127_6977207_2 EthD domain - - - 0.00000000000000000000000000000007957 128.0
HKD1_k127_6978764_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.74e-219 698.0
HKD1_k127_6978764_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 4.341e-212 664.0
HKD1_k127_6978764_10 Enoyl-(Acyl carrier protein) reductase K00059,K10780 - 1.1.1.100,1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000005561 248.0
HKD1_k127_6978764_11 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000004709 239.0
HKD1_k127_6978764_12 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000001433 239.0
HKD1_k127_6978764_13 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000008005 211.0
HKD1_k127_6978764_14 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000007908 163.0
HKD1_k127_6978764_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 605.0
HKD1_k127_6978764_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 556.0
HKD1_k127_6978764_4 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 543.0
HKD1_k127_6978764_5 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 433.0
HKD1_k127_6978764_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 434.0
HKD1_k127_6978764_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 420.0
HKD1_k127_6978764_8 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 400.0
HKD1_k127_6978764_9 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001515 272.0
HKD1_k127_7020807_0 PFAM iron-containing alcohol dehydrogenase K00001,K11173,K13954 - 1.1.1.1,1.1.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 552.0
HKD1_k127_7020807_1 quinone binding K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 373.0
HKD1_k127_7020807_2 Pfam:DUF59 - - - 0.0000000000000000000000002327 111.0
HKD1_k127_7053738_0 Hep Hag repeat protein - - - 0.0000000000000000000000000000001383 134.0
HKD1_k127_7053738_1 - - - - 0.000000000006677 70.0
HKD1_k127_7053738_2 - - - - 0.000002591 56.0
HKD1_k127_7055170_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1035.0
HKD1_k127_7055170_1 xanthine dehydrogenase activity K04108 - 1.3.7.9 0.0 1030.0
HKD1_k127_7055170_10 Uncharacterised protein family (UPF0261) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 444.0
HKD1_k127_7055170_11 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 430.0
HKD1_k127_7055170_12 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 416.0
HKD1_k127_7055170_13 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 405.0
HKD1_k127_7055170_14 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 424.0
HKD1_k127_7055170_15 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 407.0
HKD1_k127_7055170_16 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 395.0
HKD1_k127_7055170_17 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 398.0
HKD1_k127_7055170_18 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 368.0
HKD1_k127_7055170_19 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 369.0
HKD1_k127_7055170_2 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 1.261e-308 976.0
HKD1_k127_7055170_20 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 387.0
HKD1_k127_7055170_21 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 356.0
HKD1_k127_7055170_22 Belongs to the TtcA family K21947 - 2.8.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 353.0
HKD1_k127_7055170_23 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 351.0
HKD1_k127_7055170_24 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 335.0
HKD1_k127_7055170_25 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 344.0
HKD1_k127_7055170_26 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 339.0
HKD1_k127_7055170_27 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 308.0
HKD1_k127_7055170_28 Histidine kinase K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 326.0
HKD1_k127_7055170_29 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 304.0
HKD1_k127_7055170_3 AMP-binding enzyme C-terminal domain - - - 9.757e-256 801.0
HKD1_k127_7055170_30 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002312 283.0
HKD1_k127_7055170_31 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009852 295.0
HKD1_k127_7055170_32 COG0006 Xaa-Pro aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003074 289.0
HKD1_k127_7055170_33 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000006383 264.0
HKD1_k127_7055170_34 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000007654 252.0
HKD1_k127_7055170_35 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003083 271.0
HKD1_k127_7055170_36 Allophanate hydrolase subunit 2 K06350 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001715 272.0
HKD1_k127_7055170_37 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000004746 235.0
HKD1_k127_7055170_38 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000003119 229.0
HKD1_k127_7055170_39 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000004283 233.0
HKD1_k127_7055170_4 Enoyl-CoA hydratase/isomerase - - - 6.492e-243 762.0
HKD1_k127_7055170_40 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000003137 206.0
HKD1_k127_7055170_41 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000001008 190.0
HKD1_k127_7055170_42 Pfam:AHS1 - - - 0.000000000000000000000000000000000000000000000007507 182.0
HKD1_k127_7055170_43 endonuclease activity - - - 0.000000000000000000000000000000000000000000001031 176.0
HKD1_k127_7055170_44 endonuclease activity - - - 0.0000000000000000000000000000000000000000214 162.0
HKD1_k127_7055170_46 HD domain - - - 0.00000000000000000000000002171 127.0
HKD1_k127_7055170_47 - - - - 0.000000000000000000002766 96.0
HKD1_k127_7055170_48 Cupin 2 conserved barrel domain protein - - - 0.0000000000000000002252 95.0
HKD1_k127_7055170_49 DinB superfamily - - - 0.00000002055 63.0
HKD1_k127_7055170_5 benzoyl-CoA oxygenase - - - 4.322e-241 764.0
HKD1_k127_7055170_50 ThiS family K03154 - - 0.00000002411 63.0
HKD1_k127_7055170_51 solute binding protein K02035 - - 0.0002437 51.0
HKD1_k127_7055170_6 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 2.74e-229 741.0
HKD1_k127_7055170_7 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 2.319e-226 714.0
HKD1_k127_7055170_8 Flavin-binding monooxygenase-like K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 446.0
HKD1_k127_7055170_9 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 468.0
HKD1_k127_7058636_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009156 565.0
HKD1_k127_7058636_1 transferase activity, transferring glycosyl groups K12996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 469.0
HKD1_k127_7058636_10 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000001329 181.0
HKD1_k127_7058636_11 Glycosyl transferases group 1 K21001 - - 0.0000000000000000000000000000000000000008002 171.0
HKD1_k127_7058636_12 Polysaccharide biosynthesis protein K03328 - - 0.0000000000000000000000000000000001561 153.0
HKD1_k127_7058636_13 Tetratricopeptide repeat - - - 0.000000000000000000006715 109.0
HKD1_k127_7058636_14 Glycosyl transferase family 2 - - - 0.0000000000000000001196 103.0
HKD1_k127_7058636_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 318.0
HKD1_k127_7058636_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009676 322.0
HKD1_k127_7058636_4 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 307.0
HKD1_k127_7058636_5 glycosyl transferase family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000001298 237.0
HKD1_k127_7058636_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000001603 222.0
HKD1_k127_7058636_7 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001133 219.0
HKD1_k127_7058636_8 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000005243 217.0
HKD1_k127_7058636_9 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000000000000000000000000000001076 179.0
HKD1_k127_7065968_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 2.889e-267 836.0
HKD1_k127_7065968_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 455.0
HKD1_k127_7065968_2 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 301.0
HKD1_k127_7065968_3 Binding-protein-dependent transport system inner membrane component K10229 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001795 266.0
HKD1_k127_7065968_4 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001044 242.0
HKD1_k127_7065968_5 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000003233 223.0
HKD1_k127_7065968_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000004012 213.0
HKD1_k127_7065968_7 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000001097 170.0
HKD1_k127_7068718_0 PFAM Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 585.0
HKD1_k127_7068718_1 AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 467.0
HKD1_k127_7068718_2 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 412.0
HKD1_k127_7068718_3 PFAM Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 343.0
HKD1_k127_7068718_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 308.0
HKD1_k127_7068718_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001362 276.0
HKD1_k127_7068718_6 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.0000000000000000000000000000000000000000001422 171.0
HKD1_k127_7068718_7 PhoQ Sensor - - - 0.0000000000000000000000000000002884 134.0
HKD1_k127_7068718_8 - - - - 0.00000000000000000000002245 114.0
HKD1_k127_7074345_0 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 590.0
HKD1_k127_7074345_1 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000003844 144.0
HKD1_k127_7074345_2 Winged helix DNA-binding domain K09927 - - 0.0000000000000002083 87.0
HKD1_k127_7074345_3 Cytochrome c - - - 0.000000000001135 75.0
HKD1_k127_7074345_4 Protein of unknown function (DUF1573) - - - 0.0001095 50.0
HKD1_k127_7111211_0 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 326.0
HKD1_k127_7111211_1 Cobalamin-independent synthase, Catalytic domain K00549,K22363 - 2.1.1.14,4.4.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 297.0
HKD1_k127_7111211_2 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008502 292.0
HKD1_k127_7111211_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000901 287.0
HKD1_k127_7111211_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000008584 230.0
HKD1_k127_7111211_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000004618 224.0
HKD1_k127_7111211_6 Histidine kinase - - - 0.000000000000000000001128 102.0
HKD1_k127_711144_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 327.0
HKD1_k127_711144_1 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001426 274.0
HKD1_k127_711144_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004303 240.0
HKD1_k127_711144_3 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000002075 207.0
HKD1_k127_711144_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000007005 172.0
HKD1_k127_711144_5 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000008087 123.0
HKD1_k127_711144_6 response to nickel cation - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0040008,GO:0045926,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0065007,GO:0097159,GO:1901363 - 0.0000000000000001329 87.0
HKD1_k127_7139087_0 Gaf domain - - - 0.000000000000000000000000000000000000000000000000000000000001459 214.0
HKD1_k127_7139087_1 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050,K15554 - - 0.0000000000000000000000000000000000000000000000000000002213 207.0
HKD1_k127_7139087_10 Matrix metallopeptidase 16b (membrane-inserted) K07763,K07995,K07996,K07997,K08002,K08003 GO:0000003,GO:0000902,GO:0000904,GO:0001501,GO:0001503,GO:0001838,GO:0001958,GO:0002009,GO:0002165,GO:0002218,GO:0002253,GO:0002376,GO:0002682,GO:0002684,GO:0003007,GO:0003143,GO:0003144,GO:0003313,GO:0003314,GO:0003315,GO:0003318,GO:0003319,GO:0003674,GO:0003824,GO:0004175,GO:0004177,GO:0004222,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005796,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006928,GO:0006929,GO:0006935,GO:0006950,GO:0007154,GO:0007267,GO:0007275,GO:0007276,GO:0007292,GO:0007399,GO:0007409,GO:0007411,GO:0007413,GO:0007417,GO:0007419,GO:0007424,GO:0007426,GO:0007444,GO:0007503,GO:0007505,GO:0007507,GO:0007552,GO:0007560,GO:0007561,GO:0008037,GO:0008038,GO:0008045,GO:0008047,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008283,GO:0008285,GO:0009056,GO:0009605,GO:0009611,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009886,GO:0009887,GO:0009888,GO:0009897,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010467,GO:0010646,GO:0010648,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0016331,GO:0016477,GO:0016485,GO:0016787,GO:0019538,GO:0019953,GO:0022008,GO:0022411,GO:0022414,GO:0022617,GO:0023051,GO:0023052,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030178,GO:0030182,GO:0030198,GO:0030234,GO:0030425,GO:0030574,GO:0030728,GO:0031175,GO:0031224,GO:0031226,GO:0031347,GO:0031349,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032963,GO:0032989,GO:0032990,GO:0034330,GO:0034769,GO:0035050,GO:0035148,GO:0035202,GO:0035239,GO:0035295,GO:0035988,GO:0036075,GO:0036477,GO:0040011,GO:0040036,GO:0040037,GO:0042060,GO:0042127,GO:0042221,GO:0042330,GO:0042995,GO:0043005,GO:0043009,GO:0043062,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044087,GO:0044093,GO:0044238,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0045088,GO:0045089,GO:0045165,GO:0045168,GO:0045216,GO:0046331,GO:0046528,GO:0046529,GO:0046872,GO:0046914,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048523,GO:0048562,GO:0048563,GO:0048568,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048701,GO:0048704,GO:0048705,GO:0048706,GO:0048707,GO:0048729,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051179,GO:0051604,GO:0051674,GO:0051704,GO:0060348,GO:0060349,GO:0060350,GO:0060429,GO:0060541,GO:0060562,GO:0060612,GO:0060828,GO:0060973,GO:0061448,GO:0061564,GO:0065007,GO:0065009,GO:0070006,GO:0070011,GO:0070013,GO:0071704,GO:0071711,GO:0071840,GO:0071944,GO:0072091,GO:0072175,GO:0072359,GO:0080134,GO:0090090,GO:0090287,GO:0090288,GO:0097094,GO:0097156,GO:0097447,GO:0097458,GO:0097485,GO:0098552,GO:0098772,GO:0106030,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:0140096,GO:1901201,GO:1901202,GO:1901564,GO:1903053,GO:1903054,GO:1904888,GO:1990834,GO:2000647 3.4.24.80 0.0003533 51.0
HKD1_k127_7139087_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000005297 212.0
HKD1_k127_7139087_3 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000004982 181.0
HKD1_k127_7139087_4 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000000000000000002843 156.0
HKD1_k127_7139087_5 AMP-binding enzyme C-terminal domain K02364 - 6.3.2.14 0.0000000000000000000000000000000000000001216 165.0
HKD1_k127_7139087_6 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000001054 147.0
HKD1_k127_7139087_7 AMP-binding enzyme C-terminal domain K16029 - - 0.00000000000000000000000000003772 133.0
HKD1_k127_7139087_8 taurine ABC transporter K15551 - - 0.000000001614 71.0
HKD1_k127_7139087_9 Caspase domain - - - 0.000004268 58.0
HKD1_k127_7151107_0 Domain of unknown function (DUF3394) - - - 1.616e-303 943.0
HKD1_k127_7151107_1 Adenylate and Guanylate cyclase catalytic domain - - - 3.134e-302 960.0
HKD1_k127_7151107_10 Dehydrogenase K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 333.0
HKD1_k127_7151107_11 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 319.0
HKD1_k127_7151107_12 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002487 280.0
HKD1_k127_7151107_13 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007604 289.0
HKD1_k127_7151107_14 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009795 284.0
HKD1_k127_7151107_15 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003079 265.0
HKD1_k127_7151107_16 Dehydrogenase E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009506 267.0
HKD1_k127_7151107_17 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000002287 247.0
HKD1_k127_7151107_18 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000006736 228.0
HKD1_k127_7151107_19 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000002942 173.0
HKD1_k127_7151107_2 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) - - - 7.91e-215 677.0
HKD1_k127_7151107_20 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000000005563 166.0
HKD1_k127_7151107_21 - - - - 0.0000000000000000000000000000000000005923 144.0
HKD1_k127_7151107_22 Cobalamin B12-binding K01849 - 5.4.99.2 0.000000000000000000000000000000000505 134.0
HKD1_k127_7151107_23 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000002338 125.0
HKD1_k127_7151107_24 acetyltransferase K00661 - 2.3.1.79 0.00000000000000000000001784 109.0
HKD1_k127_7151107_25 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000006975 87.0
HKD1_k127_7151107_26 Helix-turn-helix - - - 0.000000000004475 73.0
HKD1_k127_7151107_27 - - - - 0.00002688 55.0
HKD1_k127_7151107_3 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 517.0
HKD1_k127_7151107_4 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 488.0
HKD1_k127_7151107_5 Methylmalonyl-CoA mutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 476.0
HKD1_k127_7151107_6 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 455.0
HKD1_k127_7151107_7 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 395.0
HKD1_k127_7151107_8 Acyl-CoA dehydrogenase, N-terminal domain K18244 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 387.0
HKD1_k127_7151107_9 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 338.0
HKD1_k127_7160604_0 Belongs to the thiolase family K00626 - 2.3.1.9 3.953e-202 636.0
HKD1_k127_7160604_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008113 541.0
HKD1_k127_7160604_10 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009883 248.0
HKD1_k127_7160604_11 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009705 253.0
HKD1_k127_7160604_12 - - - - 0.0000000000000000000000000000000000000000002205 166.0
HKD1_k127_7160604_13 - - - - 0.00000000000000000000000000000000001942 140.0
HKD1_k127_7160604_14 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000008645 113.0
HKD1_k127_7160604_15 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000002958 108.0
HKD1_k127_7160604_16 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000004159 85.0
HKD1_k127_7160604_17 SpoVT / AbrB like domain - - - 0.00000000001972 66.0
HKD1_k127_7160604_2 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 514.0
HKD1_k127_7160604_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 465.0
HKD1_k127_7160604_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 344.0
HKD1_k127_7160604_5 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 314.0
HKD1_k127_7160604_6 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 312.0
HKD1_k127_7160604_7 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 303.0
HKD1_k127_7160604_8 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 293.0
HKD1_k127_7160604_9 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002087 268.0
HKD1_k127_7161600_0 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 376.0
HKD1_k127_7161600_1 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 347.0
HKD1_k127_7161600_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000004608 147.0
HKD1_k127_7179262_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 2.517e-276 889.0
HKD1_k127_7179262_1 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 3.812e-231 727.0
HKD1_k127_7179262_10 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 430.0
HKD1_k127_7179262_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 352.0
HKD1_k127_7179262_12 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002462 254.0
HKD1_k127_7179262_13 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000008383 261.0
HKD1_k127_7179262_14 imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000003844 237.0
HKD1_k127_7179262_15 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000001292 246.0
HKD1_k127_7179262_16 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000001432 245.0
HKD1_k127_7179262_17 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000001603 231.0
HKD1_k127_7179262_18 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000002385 245.0
HKD1_k127_7179262_19 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000007452 235.0
HKD1_k127_7179262_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 2.113e-210 662.0
HKD1_k127_7179262_20 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000005804 222.0
HKD1_k127_7179262_21 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000002454 213.0
HKD1_k127_7179262_22 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000001644 199.0
HKD1_k127_7179262_23 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000001375 208.0
HKD1_k127_7179262_24 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000006875 193.0
HKD1_k127_7179262_25 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000131 186.0
HKD1_k127_7179262_26 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000004616 173.0
HKD1_k127_7179262_27 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000001723 169.0
HKD1_k127_7179262_28 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000001827 150.0
HKD1_k127_7179262_29 Binds the 23S rRNA K02909 - - 0.00000000000000000000000006967 109.0
HKD1_k127_7179262_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 8.678e-204 659.0
HKD1_k127_7179262_30 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000005724 75.0
HKD1_k127_7179262_31 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000001835 64.0
HKD1_k127_7179262_32 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000001443 68.0
HKD1_k127_7179262_33 - - - - 0.00000005261 62.0
HKD1_k127_7179262_4 KaiC K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 514.0
HKD1_k127_7179262_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 490.0
HKD1_k127_7179262_6 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000995 494.0
HKD1_k127_7179262_7 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 470.0
HKD1_k127_7179262_8 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 444.0
HKD1_k127_7179262_9 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 421.0
HKD1_k127_7182097_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 2.795e-229 727.0
HKD1_k127_7182097_1 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 558.0
HKD1_k127_7182097_10 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000006181 234.0
HKD1_k127_7182097_11 Molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000001515 227.0
HKD1_k127_7182097_12 domain protein - - - 0.00000000000000000000000000000000000000000000000000009057 197.0
HKD1_k127_7182097_13 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000002261 185.0
HKD1_k127_7182097_14 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000019 184.0
HKD1_k127_7182097_15 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000003824 164.0
HKD1_k127_7182097_16 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000004363 139.0
HKD1_k127_7182097_17 Protein of unknown function (DUF2914) - - - 0.00000000000000000000000000002169 130.0
HKD1_k127_7182097_18 Histidine kinase - - - 0.0000000000000000000000008149 108.0
HKD1_k127_7182097_19 PBP superfamily domain K05772 - - 0.00000007674 53.0
HKD1_k127_7182097_2 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 395.0
HKD1_k127_7182097_20 Protein of unknown function (DUF465) K09794 - - 0.000003592 52.0
HKD1_k127_7182097_3 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 376.0
HKD1_k127_7182097_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 357.0
HKD1_k127_7182097_5 Belongs to the ABC transporter superfamily K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 311.0
HKD1_k127_7182097_6 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 293.0
HKD1_k127_7182097_7 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 302.0
HKD1_k127_7182097_8 Enoyl-CoA hydratase/isomerase K01661 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000132 286.0
HKD1_k127_7182097_9 Radical SAM domain protein K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001169 276.0
HKD1_k127_71869_0 Hsp70 protein K04043,K04044 - - 7.196e-222 703.0
HKD1_k127_71869_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 548.0
HKD1_k127_71869_10 protein conserved in bacteria - - - 0.000000000001103 68.0
HKD1_k127_71869_11 CopG antitoxin of type II toxin-antitoxin system - - - 0.000001973 53.0
HKD1_k127_71869_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000001513 252.0
HKD1_k127_71869_3 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000002419 222.0
HKD1_k127_71869_4 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000001904 145.0
HKD1_k127_71869_5 Transcriptional regulator - - - 0.000000000000000000000000000000003748 136.0
HKD1_k127_71869_6 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005515,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:1901564 - 0.0000000000000000000000000000001923 128.0
HKD1_k127_71869_7 DnaJ molecular chaperone homology domain K04082 - - 0.0000000000000000000000003552 113.0
HKD1_k127_71869_8 Protein of unknown function DUF86 - - - 0.00000000000000001522 92.0
HKD1_k127_71869_9 Nucleotidyltransferase domain K07076 - - 0.00000000000003429 78.0
HKD1_k127_7208370_0 lipopolysaccharide transport K22110 - - 0.0 1304.0
HKD1_k127_7208370_1 AMP-binding enzyme C-terminal domain K00666 - - 3.972e-279 866.0
HKD1_k127_7208370_10 the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 466.0
HKD1_k127_7208370_11 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 428.0
HKD1_k127_7208370_12 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01003,K01841 - 4.1.1.3,5.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 437.0
HKD1_k127_7208370_13 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 424.0
HKD1_k127_7208370_14 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 427.0
HKD1_k127_7208370_15 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 437.0
HKD1_k127_7208370_16 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 413.0
HKD1_k127_7208370_17 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 400.0
HKD1_k127_7208370_18 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 390.0
HKD1_k127_7208370_19 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 380.0
HKD1_k127_7208370_2 Belongs to the transketolase family K00163 - 1.2.4.1 5.778e-226 728.0
HKD1_k127_7208370_20 Enoyl-(Acyl carrier protein) reductase K00034 - 1.1.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 374.0
HKD1_k127_7208370_21 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 376.0
HKD1_k127_7208370_22 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 379.0
HKD1_k127_7208370_23 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 350.0
HKD1_k127_7208370_24 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 340.0
HKD1_k127_7208370_25 Predicted permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 343.0
HKD1_k127_7208370_26 ABC transporter permease K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 335.0
HKD1_k127_7208370_27 extracellular solute-binding protein, family 5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009197 358.0
HKD1_k127_7208370_28 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 321.0
HKD1_k127_7208370_29 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 303.0
HKD1_k127_7208370_3 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 8.501e-195 623.0
HKD1_k127_7208370_30 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 307.0
HKD1_k127_7208370_31 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 298.0
HKD1_k127_7208370_32 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004135 282.0
HKD1_k127_7208370_33 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000004728 280.0
HKD1_k127_7208370_34 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000004044 263.0
HKD1_k127_7208370_35 phosphorelay sensor kinase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000002337 266.0
HKD1_k127_7208370_36 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000001805 254.0
HKD1_k127_7208370_37 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000001034 259.0
HKD1_k127_7208370_38 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000006318 235.0
HKD1_k127_7208370_39 tRNA processing K04075,K14058 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000001241 220.0
HKD1_k127_7208370_4 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 610.0
HKD1_k127_7208370_40 Low molecular weight phosphatase family K03741 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 0.00000000000000000000000000000000000000000000000000000002076 201.0
HKD1_k127_7208370_41 3-beta hydroxysteroid dehydrogenase/isomerase family K18981 - 1.1.1.203 0.000000000000000000000000000000000000000000000000000000528 204.0
HKD1_k127_7208370_42 metallopeptidase activity K03933 - - 0.00000000000000000000000000000000000000000000000000001267 203.0
HKD1_k127_7208370_43 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000004485 205.0
HKD1_k127_7208370_44 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000001386 181.0
HKD1_k127_7208370_45 Protein of unknown function (DUF1566) - - - 0.0000000000000000000000000000000000000000001462 179.0
HKD1_k127_7208370_46 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000001827 154.0
HKD1_k127_7208370_47 Single cache domain 3 - - - 0.00000000000000000000000000000000000004824 162.0
HKD1_k127_7208370_48 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000009827 160.0
HKD1_k127_7208370_49 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000000166 147.0
HKD1_k127_7208370_5 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 544.0
HKD1_k127_7208370_50 PFAM cytoplasmic chaperone TorD family protein - - - 0.00000000000000000000000000000000181 138.0
HKD1_k127_7208370_51 toxic component of a - - - 0.000000000000000039 81.0
HKD1_k127_7208370_52 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000006545 75.0
HKD1_k127_7208370_53 Putative zinc-finger - - - 0.00000000007741 65.0
HKD1_k127_7208370_54 Belongs to the 'phage' integrase family - - - 0.00000001345 63.0
HKD1_k127_7208370_55 Phage integrase family - - - 0.00000005374 61.0
HKD1_k127_7208370_56 glycosyl transferase group 1 - - - 0.0000002593 59.0
HKD1_k127_7208370_57 - - - - 0.0002365 52.0
HKD1_k127_7208370_58 E1-E2 ATPase - - - 0.0002876 48.0
HKD1_k127_7208370_6 PFAM beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 527.0
HKD1_k127_7208370_7 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 525.0
HKD1_k127_7208370_8 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 464.0
HKD1_k127_7208370_9 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 453.0
HKD1_k127_7236540_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.763e-205 657.0
HKD1_k127_7236540_1 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001851 247.0
HKD1_k127_7236540_2 formate dehydrogenase K00127 - - 0.0000000000000000000000001756 115.0
HKD1_k127_7239057_0 COG3385 FOG Transposase and inactivated derivatives - - - 0.000000000000000216 83.0
HKD1_k127_7242147_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 1.134e-275 856.0
HKD1_k127_7242147_1 Gaf domain - - - 4.387e-201 656.0
HKD1_k127_7242147_10 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 368.0
HKD1_k127_7242147_11 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 345.0
HKD1_k127_7242147_12 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 328.0
HKD1_k127_7242147_13 Belongs to the ABC transporter superfamily K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 328.0
HKD1_k127_7242147_14 ATPases associated with a variety of cellular activities K02028,K02029,K09972,K10004 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 329.0
HKD1_k127_7242147_15 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 300.0
HKD1_k127_7242147_16 ABC transporter substrate-binding protein K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001051 297.0
HKD1_k127_7242147_17 ABC-type amino acid transport system permease component K02029,K10002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001262 280.0
HKD1_k127_7242147_18 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001177 259.0
HKD1_k127_7242147_19 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007479 254.0
HKD1_k127_7242147_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008306 579.0
HKD1_k127_7242147_20 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001207 261.0
HKD1_k127_7242147_21 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006455 250.0
HKD1_k127_7242147_22 Sigma-54 interaction domain K15836 - - 0.000000000000000000000000000000000000000000000000000000000000000009775 230.0
HKD1_k127_7242147_23 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000001103 228.0
HKD1_k127_7242147_24 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000007589 230.0
HKD1_k127_7242147_25 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000001054 218.0
HKD1_k127_7242147_26 S1/P1 Nuclease - - - 0.000000000000000000000000000000000000000000000000000000175 206.0
HKD1_k127_7242147_27 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000003032 206.0
HKD1_k127_7242147_28 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000521 185.0
HKD1_k127_7242147_29 Cytochrome c K15864 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1,1.7.99.1 0.0000000000000000000000000000000000000000002498 162.0
HKD1_k127_7242147_3 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 550.0
HKD1_k127_7242147_30 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000007111 148.0
HKD1_k127_7242147_31 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000001874 136.0
HKD1_k127_7242147_32 Methyltransferase domain K07003 - - 0.00000000000000000000000000000008418 136.0
HKD1_k127_7242147_33 major facilitator superfamily - - - 0.0000000000000000000000005834 118.0
HKD1_k127_7242147_34 GYD domain - - - 0.0000000000000000000001198 101.0
HKD1_k127_7242147_35 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000004423 99.0
HKD1_k127_7242147_36 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000001906 79.0
HKD1_k127_7242147_37 Ethylbenzene dehydrogenase - - - 0.000000000000002088 88.0
HKD1_k127_7242147_38 - - - - 0.000000000000009534 83.0
HKD1_k127_7242147_39 Antibiotic biosynthesis monooxygenase - - - 0.0000000000001194 75.0
HKD1_k127_7242147_4 belongs to the bacterial solute-binding protein 3 family K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 503.0
HKD1_k127_7242147_40 Bacterial extracellular solute-binding protein K02012 - - 0.000000000003082 78.0
HKD1_k127_7242147_41 Radical SAM superfamily K04069 - 1.97.1.4 0.00000001412 60.0
HKD1_k127_7242147_42 - - - - 0.00000004278 58.0
HKD1_k127_7242147_43 HEAT repeat - - - 0.00000008175 63.0
HKD1_k127_7242147_44 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000001174 57.0
HKD1_k127_7242147_45 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000007581 49.0
HKD1_k127_7242147_46 Domain of unknown function (DUF4157) - - - 0.0001084 54.0
HKD1_k127_7242147_5 polar amino acid transport system K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 444.0
HKD1_k127_7242147_6 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 381.0
HKD1_k127_7242147_7 ABC-type Fe3 transport system permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 395.0
HKD1_k127_7242147_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 367.0
HKD1_k127_7242147_9 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 374.0
HKD1_k127_7303418_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 4.9e-269 845.0
HKD1_k127_7303418_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.201e-214 688.0
HKD1_k127_7303418_10 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000001026 197.0
HKD1_k127_7303418_11 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000002225 205.0
HKD1_k127_7303418_12 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000004367 169.0
HKD1_k127_7303418_13 Polyketide cyclase / dehydrase and lipid transport K09386 - - 0.00000000000000000000000000000000000008605 147.0
HKD1_k127_7303418_14 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.00000000000000000000000000000001352 136.0
HKD1_k127_7303418_15 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000000000103 114.0
HKD1_k127_7303418_16 Preprotein translocase subunit YajC K03210 - - 0.0000000000000000000002271 101.0
HKD1_k127_7303418_17 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000002568 95.0
HKD1_k127_7303418_18 Glycine cleavage H-protein - - - 0.00000005365 56.0
HKD1_k127_7303418_2 PFAM extracellular solute-binding protein family 1 K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 532.0
HKD1_k127_7303418_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 507.0
HKD1_k127_7303418_4 Binding-protein-dependent transport system inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 441.0
HKD1_k127_7303418_5 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 425.0
HKD1_k127_7303418_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 392.0
HKD1_k127_7303418_7 binding-protein-dependent transport systems inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 364.0
HKD1_k127_7303418_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005147 274.0
HKD1_k127_7303418_9 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000001372 205.0
HKD1_k127_7309807_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.777e-240 764.0
HKD1_k127_7309807_1 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 408.0
HKD1_k127_7309807_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 361.0
HKD1_k127_7309807_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001427 288.0
HKD1_k127_7309807_4 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000006897 269.0
HKD1_k127_7309807_5 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.0000000000000000000000000000000000000000001873 177.0
HKD1_k127_7309807_6 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000003216 139.0
HKD1_k127_7309807_7 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000001076 131.0
HKD1_k127_7309807_8 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K15060 - - 0.0000000000000001012 80.0
HKD1_k127_7309807_9 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000002924 69.0
HKD1_k127_7313308_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1332.0
HKD1_k127_7313308_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1101.0
HKD1_k127_7313308_10 PFAM Flavocytochrome c sulphide dehydrogenase, flavin-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 389.0
HKD1_k127_7313308_11 radical SAM K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 375.0
HKD1_k127_7313308_12 4Fe-4S ferredoxin iron-sulfur binding domain protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 383.0
HKD1_k127_7313308_13 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 370.0
HKD1_k127_7313308_14 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007822 355.0
HKD1_k127_7313308_15 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 318.0
HKD1_k127_7313308_16 Cytochrome C oxidase, cbb3-type, subunit III K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 309.0
HKD1_k127_7313308_17 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 303.0
HKD1_k127_7313308_18 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000127 274.0
HKD1_k127_7313308_19 subunit beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000008355 243.0
HKD1_k127_7313308_2 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1069.0
HKD1_k127_7313308_20 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000006038 226.0
HKD1_k127_7313308_21 Lipoate-protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000001889 225.0
HKD1_k127_7313308_22 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000000000000000000000000003383 220.0
HKD1_k127_7313308_23 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000002469 199.0
HKD1_k127_7313308_24 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein - - - 0.00000000000000000000000000000000000000000000000000003528 190.0
HKD1_k127_7313308_25 glycine decarboxylation via glycine cleavage system K02437 - - 0.000000000000000000000000000000000000000000000008561 177.0
HKD1_k127_7313308_26 glycine decarboxylation via glycine cleavage system K02437 - - 0.0000000000000000000000002499 113.0
HKD1_k127_7313308_27 sulfur oxidation protein (SoxY) K17226 - - 0.0000000000000000000003708 107.0
HKD1_k127_7313308_28 PFAM Cytochrome c, class I - - - 0.000000000000000000003932 102.0
HKD1_k127_7313308_29 Sulphur transport K07112 - - 0.000000000000001666 79.0
HKD1_k127_7313308_3 Fe-S oxidoreductase - - - 7.223e-221 706.0
HKD1_k127_7313308_30 Sulphur oxidation protein SoxZ K17227 - - 0.000000000005704 72.0
HKD1_k127_7313308_31 Thioredoxin-like - - - 0.00000000001645 68.0
HKD1_k127_7313308_32 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000008305 54.0
HKD1_k127_7313308_33 Bacterial PH domain - - - 0.0009029 50.0
HKD1_k127_7313308_4 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 9.121e-198 631.0
HKD1_k127_7313308_5 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 3.071e-194 619.0
HKD1_k127_7313308_6 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 539.0
HKD1_k127_7313308_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 471.0
HKD1_k127_7313308_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 434.0
HKD1_k127_7313308_9 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 439.0
HKD1_k127_7324247_0 Adenylate and Guanylate cyclase catalytic domain - - - 2e-249 808.0
HKD1_k127_7324247_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0020037,GO:0042279,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0097164,GO:0098809,GO:1901363 1.7.2.2 1.041e-214 683.0
HKD1_k127_7324247_2 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities K00842,K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 506.0
HKD1_k127_7324247_3 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000005066 226.0
HKD1_k127_7324247_4 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000000000005237 159.0
HKD1_k127_7324247_5 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.000000000000000000000000000000000002329 149.0
HKD1_k127_7324247_6 Cupredoxin-like domain - - - 0.0000000000000000000004056 100.0
HKD1_k127_7324247_7 DUF218 domain - - - 0.0000000000855 77.0
HKD1_k127_7324256_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 2.176e-251 792.0
HKD1_k127_7324256_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.234e-220 707.0
HKD1_k127_7324256_10 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 431.0
HKD1_k127_7324256_11 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 389.0
HKD1_k127_7324256_12 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 374.0
HKD1_k127_7324256_13 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008786 356.0
HKD1_k127_7324256_14 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 325.0
HKD1_k127_7324256_15 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 316.0
HKD1_k127_7324256_16 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 302.0
HKD1_k127_7324256_17 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000001212 205.0
HKD1_k127_7324256_18 Enoyl-CoA hydratase K16425 GO:0003674,GO:0003824,GO:0004300,GO:0016829,GO:0016835,GO:0016836 - 0.0000000000000000000000000000000000000000000001893 177.0
HKD1_k127_7324256_19 PFAM transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000001456 169.0
HKD1_k127_7324256_2 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 608.0
HKD1_k127_7324256_20 Scavenger mRNA decapping enzyme C-term binding - - - 0.0000000000000000000000000000000000000003029 154.0
HKD1_k127_7324256_3 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 514.0
HKD1_k127_7324256_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 483.0
HKD1_k127_7324256_5 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 451.0
HKD1_k127_7324256_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 448.0
HKD1_k127_7324256_7 Dehydrogenase K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 435.0
HKD1_k127_7324256_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 432.0
HKD1_k127_7324256_9 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 431.0
HKD1_k127_7329315_0 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001183 281.0
HKD1_k127_7329315_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000001375 153.0
HKD1_k127_7329315_2 Glycosyl transferase 4-like domain - - - 0.00000000000000000008164 105.0
HKD1_k127_734412_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 572.0
HKD1_k127_734412_1 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 372.0
HKD1_k127_734412_10 ABC transporter permease - - - 0.00000000000000000000000000000000000000000000000000111 192.0
HKD1_k127_734412_11 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000006055 194.0
HKD1_k127_734412_12 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000003597 170.0
HKD1_k127_734412_13 Putative regulatory protein - - - 0.00000000000000000000000000000000000002592 147.0
HKD1_k127_734412_14 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000001593 146.0
HKD1_k127_734412_15 DinB family - - - 0.00000000000000004218 91.0
HKD1_k127_734412_16 Amidohydrolase K07045 - - 0.000000000001876 67.0
HKD1_k127_734412_17 dihydrolipoyl dehydrogenase activity - - - 0.0000000001227 70.0
HKD1_k127_734412_18 pfam gyd - - - 0.0001564 51.0
HKD1_k127_734412_2 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 330.0
HKD1_k127_734412_3 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 312.0
HKD1_k127_734412_4 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 299.0
HKD1_k127_734412_5 PFAM ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002321 291.0
HKD1_k127_734412_6 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001914 262.0
HKD1_k127_734412_7 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000014 261.0
HKD1_k127_734412_8 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.00000000000000000000000000000000000000000000000000000000001839 209.0
HKD1_k127_734412_9 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000007481 203.0
HKD1_k127_7353692_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 5.746e-232 737.0
HKD1_k127_7353692_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.476e-212 691.0
HKD1_k127_7353692_10 Protein of unknown function (DUF503) K09764 - - 0.0000000000000001584 89.0
HKD1_k127_7353692_11 Protein of unknown function (DUF448) K07742 - - 0.00000000000003804 77.0
HKD1_k127_7353692_2 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 413.0
HKD1_k127_7353692_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000005634 248.0
HKD1_k127_7353692_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000002676 247.0
HKD1_k127_7353692_5 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000002947 243.0
HKD1_k127_7353692_6 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000004247 134.0
HKD1_k127_7353692_7 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000261 117.0
HKD1_k127_7353692_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000004947 114.0
HKD1_k127_7353692_9 Ferredoxin - - - 0.0000000000000000002296 93.0
HKD1_k127_7360804_0 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 0.0 1913.0
HKD1_k127_7360804_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.256e-259 817.0
HKD1_k127_7360804_10 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 334.0
HKD1_k127_7360804_11 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 324.0
HKD1_k127_7360804_12 Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 300.0
HKD1_k127_7360804_13 FAD linked oxidases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 306.0
HKD1_k127_7360804_14 Coenzyme F420 hydrogenase dehydrogenase, beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003368 306.0
HKD1_k127_7360804_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K16950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005354 256.0
HKD1_k127_7360804_16 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000001474 246.0
HKD1_k127_7360804_17 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000008997 230.0
HKD1_k127_7360804_18 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000008533 202.0
HKD1_k127_7360804_19 ferredoxin oxidoreductase, subunit gamma K00177 - 1.2.7.3 0.000000000000000000000000000000000000001469 166.0
HKD1_k127_7360804_2 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 1.238e-224 713.0
HKD1_k127_7360804_20 FeoA K03709 - - 0.000000000000000000000000000000000001588 147.0
HKD1_k127_7360804_21 Rubrerythrin - - - 0.000000000000000000000000000000001394 136.0
HKD1_k127_7360804_22 PFAM Rubrerythrin - - - 0.00000000000000000000000001012 117.0
HKD1_k127_7360804_23 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.0000000000000006815 87.0
HKD1_k127_7360804_24 Malate synthase K01638 - 2.3.3.9 0.000004811 54.0
HKD1_k127_7360804_3 Bacterial extracellular solute-binding protein K02027,K05813 - - 7.567e-200 636.0
HKD1_k127_7360804_4 COG3839 ABC-type sugar transport systems, ATPase components K05816 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 464.0
HKD1_k127_7360804_5 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 463.0
HKD1_k127_7360804_6 ABC-type sugar transport system, permease component K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 411.0
HKD1_k127_7360804_7 Ferrous iron transport B domain protein K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 427.0
HKD1_k127_7360804_8 Binding-protein-dependent transport system inner membrane component K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 395.0
HKD1_k127_7360804_9 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 346.0
HKD1_k127_7395192_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 416.0
HKD1_k127_7395192_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007799 264.0
HKD1_k127_7395192_2 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000004991 217.0
HKD1_k127_7395192_3 Belongs to the TPP enzyme family - - - 0.0000000000000000000000004184 123.0
HKD1_k127_7395192_4 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000001215 98.0
HKD1_k127_7395192_5 HD domain - - - 0.0000007238 51.0
HKD1_k127_7412899_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.853e-259 829.0
HKD1_k127_7412899_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 8.047e-243 771.0
HKD1_k127_7412899_10 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 388.0
HKD1_k127_7412899_11 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 301.0
HKD1_k127_7412899_12 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000003525 240.0
HKD1_k127_7412899_13 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000001696 231.0
HKD1_k127_7412899_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000002759 223.0
HKD1_k127_7412899_15 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000003301 204.0
HKD1_k127_7412899_16 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000002303 185.0
HKD1_k127_7412899_17 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000001361 192.0
HKD1_k127_7412899_18 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000002677 173.0
HKD1_k127_7412899_19 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.00000000000000000000000000000000000000004492 168.0
HKD1_k127_7412899_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 610.0
HKD1_k127_7412899_20 EamA-like transporter family - - - 0.000000000000000000000000000000002427 141.0
HKD1_k127_7412899_21 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000628 147.0
HKD1_k127_7412899_22 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000001906 134.0
HKD1_k127_7412899_23 Tetratricopeptide repeat - - - 0.0000000000000000000000001457 119.0
HKD1_k127_7412899_24 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000003272 91.0
HKD1_k127_7412899_25 YceI-like domain - - - 0.00000000003641 72.0
HKD1_k127_7412899_26 denitrification pathway - - - 0.0003445 51.0
HKD1_k127_7412899_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 585.0
HKD1_k127_7412899_4 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 569.0
HKD1_k127_7412899_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 527.0
HKD1_k127_7412899_6 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 529.0
HKD1_k127_7412899_7 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 501.0
HKD1_k127_7412899_8 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 474.0
HKD1_k127_7412899_9 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 414.0
HKD1_k127_7435259_0 SMART helix-turn-helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000523 203.0
HKD1_k127_7435259_1 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.000000000000000000000000000000000000001132 148.0
HKD1_k127_7435259_2 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000001198 134.0
HKD1_k127_7435259_3 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000002285 82.0
HKD1_k127_7435259_4 DNA excision - - - 0.00000005386 58.0
HKD1_k127_7451749_0 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002332 268.0
HKD1_k127_7451749_1 - - - - 0.0000000000000000000000000000000000000000000000009957 190.0
HKD1_k127_7451749_2 Bacterial transcriptional regulator K02624 - - 0.000000000000000000000000000000004051 138.0
HKD1_k127_747952_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 8.917e-293 925.0
HKD1_k127_747952_1 PFAM type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 420.0
HKD1_k127_747952_10 Methyltransferase domain - - - 0.000000000000000000000000001568 124.0
HKD1_k127_747952_11 NMT1-like family K02051 - - 0.00000000001361 76.0
HKD1_k127_747952_12 RecX family K03565 - - 0.000000001597 67.0
HKD1_k127_747952_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 330.0
HKD1_k127_747952_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 337.0
HKD1_k127_747952_4 Glycosyltransferase family 28 N-terminal domain K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 334.0
HKD1_k127_747952_5 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 323.0
HKD1_k127_747952_6 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000001235 183.0
HKD1_k127_747952_7 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000001014 162.0
HKD1_k127_747952_8 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000001036 162.0
HKD1_k127_747952_9 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000001142 156.0
HKD1_k127_749717_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 448.0
HKD1_k127_749717_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000003131 220.0
HKD1_k127_7502188_0 Recombinase - - - 0.000000000000000004726 96.0
HKD1_k127_7502188_1 Resolvase, N terminal domain - - - 0.000003217 55.0
HKD1_k127_7502188_2 recombinase activity - - - 0.0002654 48.0
HKD1_k127_7534728_0 - - - - 0.000000000000000000000000000000000000000004655 162.0
HKD1_k127_7534728_1 DNA polymerase X family K02347 - - 0.0000000005547 64.0
HKD1_k127_7534728_2 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K20444 - 2.1.1.222,2.1.1.64 0.000001971 57.0
HKD1_k127_7534728_3 DNA polymerase X family K02347 - - 0.00003153 47.0
HKD1_k127_7537132_0 PFAM peptidase S9A prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 7.869e-228 728.0
HKD1_k127_7537132_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 478.0
HKD1_k127_7537132_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 450.0
HKD1_k127_7537132_3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000766 254.0
HKD1_k127_7537132_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000001294 249.0
HKD1_k127_7537132_5 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000006113 168.0
HKD1_k127_7537132_6 Protein of unknown function DUF86 - - - 0.0000000000003178 79.0
HKD1_k127_7537132_7 nucleotidyltransferase activity - - - 0.00000003218 64.0
HKD1_k127_7579262_0 von Willebrand factor (vWF) type A domain - - - 1.522e-214 688.0
HKD1_k127_7579262_1 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 3.325e-205 647.0
HKD1_k127_7579262_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 485.0
HKD1_k127_7579262_3 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 442.0
HKD1_k127_7579262_4 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 416.0
HKD1_k127_7579262_5 Copper amine oxidase N-terminal domain - - - 0.0000000000000000000000000003757 121.0
HKD1_k127_7592959_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1123.0
HKD1_k127_7592959_1 amine dehydrogenase activity K19345 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 586.0
HKD1_k127_7592959_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 299.0
HKD1_k127_7592959_11 Methyl-viologen-reducing hydrogenase, delta subunit K02572,K02573,K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 312.0
HKD1_k127_7592959_12 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001808 296.0
HKD1_k127_7592959_13 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001946 302.0
HKD1_k127_7592959_14 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008073 281.0
HKD1_k127_7592959_15 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006198 290.0
HKD1_k127_7592959_16 NAD dependent epimerase/dehydratase family K07535 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001988 280.0
HKD1_k127_7592959_17 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002754 298.0
HKD1_k127_7592959_18 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000003923 283.0
HKD1_k127_7592959_19 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003092 263.0
HKD1_k127_7592959_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 516.0
HKD1_k127_7592959_20 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002106 265.0
HKD1_k127_7592959_21 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001419 258.0
HKD1_k127_7592959_22 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000007731 245.0
HKD1_k127_7592959_23 4Fe-4S binding domain K18362 - - 0.00000000000000000000000000000000000000000000000000000000000000000006666 240.0
HKD1_k127_7592959_24 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007213 241.0
HKD1_k127_7592959_25 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000003402 244.0
HKD1_k127_7592959_26 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000101 234.0
HKD1_k127_7592959_27 4Fe-4S single cluster domain K22226 - - 0.000000000000000000000000000000000000000000000000000000003209 207.0
HKD1_k127_7592959_28 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000004864 202.0
HKD1_k127_7592959_29 Pas domain - - - 0.0000000000000000000000000000000000000000006231 177.0
HKD1_k127_7592959_3 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 499.0
HKD1_k127_7592959_30 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.000000000000000000000000000000000000000007349 160.0
HKD1_k127_7592959_31 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000002503 126.0
HKD1_k127_7592959_32 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000005235 112.0
HKD1_k127_7592959_33 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000001025 102.0
HKD1_k127_7592959_34 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.0000000000000003881 92.0
HKD1_k127_7592959_35 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000351 83.0
HKD1_k127_7592959_36 PFAM Methyltransferase type - - - 0.00000000000009771 82.0
HKD1_k127_7592959_37 Cytochrome c7 and related cytochrome c - - - 0.0000000000007626 74.0
HKD1_k127_7592959_38 Cytochrome oxidase maturation protein cbb3-type - - - 0.000000007057 65.0
HKD1_k127_7592959_39 - - - - 0.0000001992 60.0
HKD1_k127_7592959_4 denitrification pathway K02569,K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 469.0
HKD1_k127_7592959_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 409.0
HKD1_k127_7592959_6 Transcriptional regulator (AsnC family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 352.0
HKD1_k127_7592959_7 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 362.0
HKD1_k127_7592959_8 benzoyl-CoA reductase K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 332.0
HKD1_k127_7592959_9 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 314.0
HKD1_k127_759491_0 non-ribosomal peptide synthetase - - - 0.0 1636.0
HKD1_k127_759491_1 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 555.0
HKD1_k127_759491_10 Quinolinate phosphoribosyl transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000007079 229.0
HKD1_k127_759491_11 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000001603 214.0
HKD1_k127_759491_12 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000002778 194.0
HKD1_k127_759491_13 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000005067 160.0
HKD1_k127_759491_14 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000002399 147.0
HKD1_k127_759491_15 PFAM thioesterase superfamily K02614 - - 0.000000000000000000000007156 109.0
HKD1_k127_759491_16 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.00000000004526 63.0
HKD1_k127_759491_17 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000002542 66.0
HKD1_k127_759491_18 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000453 55.0
HKD1_k127_759491_19 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0001157 47.0
HKD1_k127_759491_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 458.0
HKD1_k127_759491_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 380.0
HKD1_k127_759491_4 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 390.0
HKD1_k127_759491_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 338.0
HKD1_k127_759491_6 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 335.0
HKD1_k127_759491_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 303.0
HKD1_k127_759491_8 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000125 259.0
HKD1_k127_759491_9 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000000000008599 238.0
HKD1_k127_7598573_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1039.0
HKD1_k127_7598573_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 389.0
HKD1_k127_7598573_2 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001431 273.0
HKD1_k127_7598573_3 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.00000000000000000000000000007592 133.0
HKD1_k127_7598573_4 DNA polymerase III (delta' subunit) K02340 - 2.7.7.7 0.0000000000000000002038 100.0
HKD1_k127_7598573_5 Evidence 5 No homology to any previously reported sequences K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.000000000000001344 89.0
HKD1_k127_7598573_6 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000007499 69.0
HKD1_k127_7602786_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 499.0
HKD1_k127_7602786_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 451.0
HKD1_k127_7602786_10 molybdenum ion binding K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000001795 242.0
HKD1_k127_7602786_11 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000002397 248.0
HKD1_k127_7602786_12 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000003021 213.0
HKD1_k127_7602786_13 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000457 202.0
HKD1_k127_7602786_14 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000000000000000000000001258 149.0
HKD1_k127_7602786_15 Vacuole effluxer Atg22 like - - - 0.0000000000000000000000000000000000372 150.0
HKD1_k127_7602786_16 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000004042 133.0
HKD1_k127_7602786_17 Glycosyl transferase K20444 - - 0.000000000000000002413 97.0
HKD1_k127_7602786_18 AsmA-like C-terminal region K07289 - - 0.00000001596 67.0
HKD1_k127_7602786_19 Transcriptional regulator K12146,K15836 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.0000002017 53.0
HKD1_k127_7602786_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 445.0
HKD1_k127_7602786_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 411.0
HKD1_k127_7602786_4 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 361.0
HKD1_k127_7602786_5 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 341.0
HKD1_k127_7602786_6 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 320.0
HKD1_k127_7602786_7 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766 321.0
HKD1_k127_7602786_8 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 313.0
HKD1_k127_7602786_9 PFAM Uracil-DNA glycosylase superfamily K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001605 267.0
HKD1_k127_763816_0 Pfam:DUF1446 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 593.0
HKD1_k127_763816_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 332.0
HKD1_k127_7704927_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 586.0
HKD1_k127_7704927_1 Short-chain dehydrogenase reductase Sdr K00034,K00059,K03366 - 1.1.1.100,1.1.1.304,1.1.1.47,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000002564 218.0
HKD1_k127_7704927_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000001919 74.0
HKD1_k127_7715689_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1164.0
HKD1_k127_7715689_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.69e-213 681.0
HKD1_k127_7715689_10 nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003004 287.0
HKD1_k127_7715689_11 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000009092 244.0
HKD1_k127_7715689_12 Cupin superfamily (DUF985) K09705 - - 0.00000000000000000000000000000000000000000000000000000000000000004242 227.0
HKD1_k127_7715689_13 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000001737 228.0
HKD1_k127_7715689_14 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000006471 218.0
HKD1_k127_7715689_15 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000007389 227.0
HKD1_k127_7715689_16 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000001228 203.0
HKD1_k127_7715689_17 PFAM Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000001533 201.0
HKD1_k127_7715689_18 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000000000000000009545 194.0
HKD1_k127_7715689_19 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000005524 172.0
HKD1_k127_7715689_2 Bacterial extracellular solute-binding protein K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 554.0
HKD1_k127_7715689_20 Cupin domain K11312 - - 0.00000000000000000000000000000000008887 140.0
HKD1_k127_7715689_21 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000002166 125.0
HKD1_k127_7715689_22 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000003456 118.0
HKD1_k127_7715689_24 Thioesterase superfamily - - - 0.0000000001515 74.0
HKD1_k127_7715689_25 Tetratricopeptide repeat - - - 0.0000000002861 72.0
HKD1_k127_7715689_3 Gamma-glutamyltranspeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 557.0
HKD1_k127_7715689_4 PFAM binding-protein-dependent transport systems inner membrane component K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 419.0
HKD1_k127_7715689_5 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 417.0
HKD1_k127_7715689_6 transmembrane transport K02025,K05814,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 366.0
HKD1_k127_7715689_7 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 359.0
HKD1_k127_7715689_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 312.0
HKD1_k127_7715689_9 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 313.0
HKD1_k127_7755587_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 564.0
HKD1_k127_7755587_1 Phosphopantetheine attachment site - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006094 289.0
HKD1_k127_7755587_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000256 269.0
HKD1_k127_7755587_3 SMART RNA-processing protein HAT helix repeating-containing protein - - - 0.0001404 53.0
HKD1_k127_7756411_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 3.737e-277 865.0
HKD1_k127_7756411_1 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 554.0
HKD1_k127_7756411_10 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006681 280.0
HKD1_k127_7756411_11 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001914 243.0
HKD1_k127_7756411_12 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000002587 178.0
HKD1_k127_7756411_13 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000471 160.0
HKD1_k127_7756411_14 Cyclophilin-like K09143 - - 0.00000000000000000000000000000000329 135.0
HKD1_k127_7756411_15 protein conserved in cyanobacteria - - - 0.000000004499 61.0
HKD1_k127_7756411_2 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 533.0
HKD1_k127_7756411_3 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 486.0
HKD1_k127_7756411_4 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 481.0
HKD1_k127_7756411_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 436.0
HKD1_k127_7756411_6 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 397.0
HKD1_k127_7756411_7 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 380.0
HKD1_k127_7756411_8 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 386.0
HKD1_k127_7756411_9 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 379.0
HKD1_k127_7786620_0 Sulfatase K01130 - 3.1.6.1 3.901e-288 895.0
HKD1_k127_7786620_1 Bacterial extracellular solute-binding protein K05813 - - 2.232e-194 617.0
HKD1_k127_7786620_10 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003289 266.0
HKD1_k127_7786620_11 - - - - 0.0000000000000000000000000000000000006135 159.0
HKD1_k127_7786620_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000965 109.0
HKD1_k127_7786620_13 Organic Anion Transporter Polypeptide (OATP) family - - - 0.0000002286 63.0
HKD1_k127_7786620_14 antisigma factor binding - - - 0.0002151 48.0
HKD1_k127_7786620_15 WD repeat domain 90 - - - 0.0009721 46.0
HKD1_k127_7786620_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 582.0
HKD1_k127_7786620_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008762 482.0
HKD1_k127_7786620_4 Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 346.0
HKD1_k127_7786620_5 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 363.0
HKD1_k127_7786620_6 COGs COG0647 sugar phosphatase of the HAD superfamily K01101,K02566 - 3.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 304.0
HKD1_k127_7786620_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 295.0
HKD1_k127_7786620_8 Trypsin-like serine protease K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000005687 276.0
HKD1_k127_7786620_9 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003086 261.0
HKD1_k127_7789579_0 PFAM Hydantoinase B oxoprolinase K01469,K01474 - 3.5.2.14,3.5.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 623.0
HKD1_k127_7789579_1 Hydantoinaseoxoprolinase domain protein K01469,K01473 - 3.5.2.14,3.5.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 522.0
HKD1_k127_7789579_2 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000943 233.0
HKD1_k127_7789579_3 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000008088 138.0
HKD1_k127_7789579_4 AMP-binding enzyme C-terminal domain K02182,K20034 GO:0003674,GO:0003824,GO:0003996,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044464,GO:0071704 6.2.1.44,6.2.1.48 0.0000007138 53.0
HKD1_k127_7858100_0 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 2.908e-261 826.0
HKD1_k127_7858100_1 Sulfatase K01130 - 3.1.6.1 2.167e-226 712.0
HKD1_k127_7858100_10 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 328.0
HKD1_k127_7858100_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 315.0
HKD1_k127_7858100_12 Exonuclease K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008513 261.0
HKD1_k127_7858100_13 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000001222 222.0
HKD1_k127_7858100_14 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000003965 196.0
HKD1_k127_7858100_15 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000001112 162.0
HKD1_k127_7858100_16 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000002675 149.0
HKD1_k127_7858100_17 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.0000000000000000000000000005298 123.0
HKD1_k127_7858100_18 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000001653 77.0
HKD1_k127_7858100_19 ABC transporter substrate binding protein K01989 - - 0.0000000000001393 75.0
HKD1_k127_7858100_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 561.0
HKD1_k127_7858100_20 Protein of unknown function (DUF721) - - - 0.00000000005674 72.0
HKD1_k127_7858100_21 - - - - 0.000000001789 66.0
HKD1_k127_7858100_22 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000004925 68.0
HKD1_k127_7858100_23 - - - - 0.0000002885 58.0
HKD1_k127_7858100_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 445.0
HKD1_k127_7858100_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 417.0
HKD1_k127_7858100_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 375.0
HKD1_k127_7858100_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 369.0
HKD1_k127_7858100_7 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 304.0
HKD1_k127_7858100_8 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 310.0
HKD1_k127_7858100_9 ABC-type dipeptide oligopeptide nickel transport K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 319.0
HKD1_k127_7899518_0 AMP-binding enzyme C-terminal domain K04116,K12507 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 520.0
HKD1_k127_7899518_1 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 473.0
HKD1_k127_7899518_10 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944 - 0.000002938 59.0
HKD1_k127_7899518_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 413.0
HKD1_k127_7899518_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 358.0
HKD1_k127_7899518_4 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 347.0
HKD1_k127_7899518_5 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 355.0
HKD1_k127_7899518_6 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000001127 221.0
HKD1_k127_7899518_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000000000286 169.0
HKD1_k127_7899518_8 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000008709 139.0
HKD1_k127_7899518_9 Periplasmic binding protein domain K01999 - - 0.000000000000003401 75.0
HKD1_k127_7916050_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 471.0
HKD1_k127_7916050_1 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000004107 104.0
HKD1_k127_7916050_2 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000009605 105.0
HKD1_k127_7916050_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000007462 70.0
HKD1_k127_7935959_0 DNA polymerase X family K02347,K04477 - - 2.27e-217 689.0
HKD1_k127_7935959_1 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 576.0
HKD1_k127_7935959_10 membrane K02451,K03832 - - 0.000000000001699 78.0
HKD1_k127_7935959_2 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000004097 228.0
HKD1_k127_7935959_3 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000000000000000000000000001515 194.0
HKD1_k127_7935959_4 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000003005 167.0
HKD1_k127_7935959_5 NUDIX hydrolase - - - 0.000000000000000000000000000000000000000004059 165.0
HKD1_k127_7935959_6 - - - - 0.0000000000000000000000000000000003983 133.0
HKD1_k127_7935959_7 addiction module antidote protein HigA K21498 - - 0.0000000000000000000000000003614 113.0
HKD1_k127_7935959_8 - - - - 0.00000000000000000000004654 99.0
HKD1_k127_7935959_9 PFAM DNA polymerase beta domain protein region K07075 - - 0.000000000000000000000183 100.0
HKD1_k127_7945206_0 General secretory system II protein E domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 580.0
HKD1_k127_7945206_1 alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 453.0
HKD1_k127_7945206_10 Inositol monophosphatase family K01092,K05602 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,3.1.3.25 0.00000000000000000000000000000000000000000000000000000004698 212.0
HKD1_k127_7945206_11 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000001311 194.0
HKD1_k127_7945206_12 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000001135 131.0
HKD1_k127_7945206_13 Isochorismatase family - - - 0.0000000000000000000000002442 107.0
HKD1_k127_7945206_14 PFAM Copper resistance protein CopC K07156 - - 0.00000000000000000000006374 104.0
HKD1_k127_7945206_15 Copper binding periplasmic protein CusF K07152 - - 0.00000562 55.0
HKD1_k127_7945206_2 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 364.0
HKD1_k127_7945206_3 PFAM Copper resistance D K07245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 355.0
HKD1_k127_7945206_4 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 317.0
HKD1_k127_7945206_5 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 324.0
HKD1_k127_7945206_6 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 292.0
HKD1_k127_7945206_7 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000879 252.0
HKD1_k127_7945206_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000499 257.0
HKD1_k127_7945206_9 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.00000000000000000000000000000000000000000000000000000000000000004675 240.0
HKD1_k127_799536_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 554.0
HKD1_k127_799536_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 382.0
HKD1_k127_799536_2 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000006878 219.0
HKD1_k127_799536_3 Thioredoxin domain - - - 0.00000000000000000000000002486 113.0
HKD1_k127_799536_4 Thioredoxin domain - - - 0.0000000000000000006171 88.0
HKD1_k127_799536_5 Acyl dehydratase - - - 0.00000000000000004678 91.0
HKD1_k127_799536_6 PFAM AIG2 family protein K20757 - 4.3.1.27 0.000000000000001167 82.0
HKD1_k127_799536_7 N-terminal half of MaoC dehydratase - - - 0.000000002353 65.0
HKD1_k127_818389_0 Protein of unknown function (DUF1177) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 408.0
HKD1_k127_818389_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 358.0
HKD1_k127_818389_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 365.0
HKD1_k127_818389_3 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 351.0
HKD1_k127_818389_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 333.0
HKD1_k127_818389_5 Protein of unknown function (DUF917) K09703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 303.0
HKD1_k127_818389_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003707 274.0
HKD1_k127_818389_7 Belongs to the peptidase S51 family K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.0000000000000000000000000000000000000000000000001141 185.0
HKD1_k127_818389_8 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000378 192.0
HKD1_k127_818389_9 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000005553 152.0
HKD1_k127_82892_0 Molydopterin dinucleotide binding domain K00122 - 1.17.1.9 3.309e-296 929.0
HKD1_k127_82892_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 389.0
HKD1_k127_82892_10 Protein of unknown function (DUF2905) - - - 0.0000000004308 72.0
HKD1_k127_82892_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 329.0
HKD1_k127_82892_3 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 303.0
HKD1_k127_82892_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000008691 243.0
HKD1_k127_82892_5 PFAM Stage II sporulation K06381 - - 0.00000000000000000000000000000000000000000000000000000000007226 224.0
HKD1_k127_82892_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000004475 178.0
HKD1_k127_82892_7 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000002241 169.0
HKD1_k127_82892_8 Putative tRNA binding domain K06878 - - 0.000000000000000000000000000000000000000959 150.0
HKD1_k127_82892_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000006994 132.0
HKD1_k127_854976_0 Belongs to the enoyl-CoA hydratase isomerase family K00022,K07514 - 1.1.1.35,4.2.1.17,5.3.3.8 8.916e-282 884.0
HKD1_k127_854976_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 4.552e-231 730.0
HKD1_k127_854976_10 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 268.0
HKD1_k127_854976_11 FMN-dependent dehydrogenase K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000001091 269.0
HKD1_k127_854976_12 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000003942 236.0
HKD1_k127_854976_13 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000001751 130.0
HKD1_k127_854976_14 amine dehydrogenase activity K13730 - - 0.0000000000000000000000000000000351 142.0
HKD1_k127_854976_15 Cupin domain - - - 0.0000000000000000000000000000001008 141.0
HKD1_k127_854976_16 PFAM Cupin 2 conserved barrel domain protein K21700 - - 0.000000000000000000000000000001501 123.0
HKD1_k127_854976_18 - - - - 0.000000000000000000000000000005977 126.0
HKD1_k127_854976_19 - - - - 0.00000000000000000000001214 106.0
HKD1_k127_854976_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 505.0
HKD1_k127_854976_20 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000002333 81.0
HKD1_k127_854976_21 - - - - 0.00000000000008181 74.0
HKD1_k127_854976_22 - - - - 0.00000000006812 68.0
HKD1_k127_854976_3 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 440.0
HKD1_k127_854976_4 Amino-transferase class IV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 417.0
HKD1_k127_854976_5 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 366.0
HKD1_k127_854976_6 gluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 366.0
HKD1_k127_854976_7 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 329.0
HKD1_k127_854976_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 322.0
HKD1_k127_854976_9 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 296.0
HKD1_k127_914899_0 Acetamidase/Formamidase family - - - 1.607e-237 743.0
HKD1_k127_914899_1 response regulator receiver K02481,K07714,K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 404.0
HKD1_k127_914899_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 403.0
HKD1_k127_914899_3 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 391.0
HKD1_k127_914899_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000005436 250.0
HKD1_k127_914899_5 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000001337 233.0
HKD1_k127_914899_6 NIPSNAP - - - 0.00000000000000000000000000000000000000000001302 171.0
HKD1_k127_914899_7 YCII-related domain K09780 - - 0.00000000009036 62.0
HKD1_k127_914899_8 gluconolactonase K01053 - 3.1.1.17 0.00000006417 56.0
HKD1_k127_94861_0 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 528.0
HKD1_k127_94861_1 ATPase associated with K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 399.0
HKD1_k127_94861_10 Putative zinc-finger - - - 0.000000005044 61.0
HKD1_k127_94861_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 397.0
HKD1_k127_94861_3 transferase activity, transferring glycosyl groups K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002954 272.0
HKD1_k127_94861_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001739 258.0
HKD1_k127_94861_5 Histidine kinase K02482,K18143 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000002085 216.0
HKD1_k127_94861_6 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000006895 186.0
HKD1_k127_94861_7 Thioredoxin-like - - - 0.0000000000000000000000000000000000007483 144.0
HKD1_k127_94861_8 TPR Domain containing protein K12600 - - 0.0000000000000000005398 101.0
HKD1_k127_94861_9 manually curated - - - 0.0000000000007309 70.0