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Overview

ID MAG01711
Name HKD1_bin.24
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order Anaerolineales
Family UBA4823
Genus FEB-25
Species
Assembly information
Completeness (%) 89.58
Contamination (%) 2.1
GC content (%) 50.0
N50 (bp) 27,189
Genome size (bp) 3,841,661

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3229

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1016612_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1214.0
HKD1_k127_1016612_1 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 562.0
HKD1_k127_1016612_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000000002904 179.0
HKD1_k127_1016612_3 Baseplate J-like protein K01218 - 3.2.1.78 0.000000000000000000000000000000001692 138.0
HKD1_k127_1016612_4 Protein of unknown function (DUF1461) - - - 0.0000000000000000000001895 103.0
HKD1_k127_1042173_0 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 451.0
HKD1_k127_1050808_0 PFAM Acetyl xylan esterase K01060 - 3.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 495.0
HKD1_k127_1050808_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 398.0
HKD1_k127_1050808_2 DUF35 OB-fold domain, acyl-CoA-associated K07068,K07549 - - 0.00000000000000000000549 98.0
HKD1_k127_1050808_3 Protein of unknown function (DUF2877) - - - 0.0000000000000000499 92.0
HKD1_k127_1050808_4 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.0000000001064 64.0
HKD1_k127_1058552_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 5.369e-287 890.0
HKD1_k127_1058552_1 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 8.66e-254 796.0
HKD1_k127_1058552_10 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003693 293.0
HKD1_k127_1058552_11 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000003597 234.0
HKD1_k127_1058552_12 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000239 215.0
HKD1_k127_1058552_13 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000002147 214.0
HKD1_k127_1058552_14 peptidase dimerisation domain protein K01436 - - 0.00000000000000000000000000000000000000000000000000002167 193.0
HKD1_k127_1058552_15 FCD - - - 0.00000000000000000000005568 108.0
HKD1_k127_1058552_16 - - - - 0.000000000000000000005283 98.0
HKD1_k127_1058552_17 HTH domain - - - 0.0000000000124 73.0
HKD1_k127_1058552_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 501.0
HKD1_k127_1058552_3 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 471.0
HKD1_k127_1058552_4 Peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 433.0
HKD1_k127_1058552_5 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007653 415.0
HKD1_k127_1058552_6 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 359.0
HKD1_k127_1058552_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 332.0
HKD1_k127_1058552_8 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 324.0
HKD1_k127_1058552_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K03615 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 297.0
HKD1_k127_1093188_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.26e-309 968.0
HKD1_k127_1093188_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 374.0
HKD1_k127_1093188_10 Phospholipid methyltransferase - - - 0.00000000000005006 80.0
HKD1_k127_1093188_2 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001059 267.0
HKD1_k127_1093188_3 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000000000000000000009949 197.0
HKD1_k127_1093188_4 Methyltransferase - - - 0.000000000000000000000000000000000000000000002363 174.0
HKD1_k127_1093188_5 Hypothetical methyltransferase - - - 0.00000000000000000000000000000000000000000003211 169.0
HKD1_k127_1093188_6 MarR family - - - 0.000000000000000000000000000000000000005149 151.0
HKD1_k127_1093188_7 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000001286 116.0
HKD1_k127_1093188_8 WD domain, G-beta repeat - - - 0.0000000000000000000000001153 124.0
HKD1_k127_1093188_9 Putative ATPase subunit of terminase (gpP-like) - - - 0.000000000000000006517 87.0
HKD1_k127_1136343_0 PFAM glycoside hydrolase family 65 central catalytic - - - 9.745e-288 899.0
HKD1_k127_1136343_1 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 1.718e-227 718.0
HKD1_k127_1136343_10 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 319.0
HKD1_k127_1136343_11 COG1175 ABC-type sugar transport systems permease components K10233 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 308.0
HKD1_k127_1136343_12 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 289.0
HKD1_k127_1136343_13 glycerophosphodiester transmembrane transport K02026,K10234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001204 280.0
HKD1_k127_1136343_14 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000004019 250.0
HKD1_k127_1136343_15 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001232 248.0
HKD1_k127_1136343_16 ABC transporter, substratebinding protein K10232 - - 0.0000000000000000000000000000000000000000000000000007403 201.0
HKD1_k127_1136343_17 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000002721 177.0
HKD1_k127_1136343_18 Protein of unknown function (DUF402) - - - 0.000000000000000000000000000000000000007748 153.0
HKD1_k127_1136343_19 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000003381 136.0
HKD1_k127_1136343_2 PFAM extracellular solute-binding protein family 1 K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 586.0
HKD1_k127_1136343_20 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000002592 100.0
HKD1_k127_1136343_21 SnoaL-like domain - - - 0.000000000000009142 80.0
HKD1_k127_1136343_23 F420H(2)-dependent quinone reductase - - - 0.0008007 44.0
HKD1_k127_1136343_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 532.0
HKD1_k127_1136343_4 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 536.0
HKD1_k127_1136343_5 Thermophilic metalloprotease (M29) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 503.0
HKD1_k127_1136343_6 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 456.0
HKD1_k127_1136343_7 helix_turn _helix lactose operon repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 453.0
HKD1_k127_1136343_8 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 436.0
HKD1_k127_1136343_9 PFAM zinc iron permease K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 344.0
HKD1_k127_1138741_0 phospholipase C K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 591.0
HKD1_k127_1138741_1 Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 587.0
HKD1_k127_1138741_10 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000001418 200.0
HKD1_k127_1138741_11 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000006803 145.0
HKD1_k127_1138741_12 COG1943 Transposase and inactivated derivatives K07491 - - 0.0000000000000000000000000000000002373 138.0
HKD1_k127_1138741_13 Glyoxalase-like domain K06996 - - 0.0000000000000000000002614 100.0
HKD1_k127_1138741_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000003218 87.0
HKD1_k127_1138741_15 SNARE associated Golgi protein K19302 - 3.6.1.27 0.0000000294 63.0
HKD1_k127_1138741_16 E-Z type HEAT repeats - - - 0.0000006028 59.0
HKD1_k127_1138741_2 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 419.0
HKD1_k127_1138741_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 328.0
HKD1_k127_1138741_4 Sodium/hydrogen exchanger family K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 341.0
HKD1_k127_1138741_5 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 314.0
HKD1_k127_1138741_6 teichoic acid transport K01990,K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001199 281.0
HKD1_k127_1138741_7 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003104 282.0
HKD1_k127_1138741_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006281 265.0
HKD1_k127_1138741_9 Transposase - - - 0.000000000000000000000000000000000000000000000000000000004924 204.0
HKD1_k127_1148163_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1731.0
HKD1_k127_1148163_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 2.718e-235 736.0
HKD1_k127_1148163_10 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001477 244.0
HKD1_k127_1148163_11 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000000000000000000000000000000000000000000000000000000006412 243.0
HKD1_k127_1148163_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000001685 213.0
HKD1_k127_1148163_13 pseudouridine synthase activity K06178,K06181,K06183 - 5.4.99.19,5.4.99.20,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000001284 230.0
HKD1_k127_1148163_14 - - - - 0.00000000000000000000000000000000000000000000000000000135 202.0
HKD1_k127_1148163_15 - - - - 0.00000000000000000000000000000000000000000002792 175.0
HKD1_k127_1148163_16 - - - - 0.00000000000000000000000000000783 128.0
HKD1_k127_1148163_17 - - - - 0.000000000000000000000000000008284 128.0
HKD1_k127_1148163_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 476.0
HKD1_k127_1148163_21 Glycine zipper 2TM domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.0000002693 62.0
HKD1_k127_1148163_3 WD-40 repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 490.0
HKD1_k127_1148163_4 Carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 435.0
HKD1_k127_1148163_5 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 370.0
HKD1_k127_1148163_6 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 303.0
HKD1_k127_1148163_7 PFAM metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 293.0
HKD1_k127_1148163_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007335 287.0
HKD1_k127_1148163_9 Domain of unknown function (DUF4349) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006394 268.0
HKD1_k127_1187213_0 elongation factor Tu domain 2 protein K02355 - - 0.0 1019.0
HKD1_k127_1187213_1 peptidase M24 K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 404.0
HKD1_k127_1187213_2 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006464 268.0
HKD1_k127_1187213_3 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000002951 264.0
HKD1_k127_1187213_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.0000000000000000000000000000000000000000000000000000000000000000008538 240.0
HKD1_k127_1187213_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000007866 224.0
HKD1_k127_1187213_6 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000000005924 224.0
HKD1_k127_1187213_7 methyltransferase activity K00569 - 2.1.1.67 0.0000000000000000000000000000000000000000000009441 173.0
HKD1_k127_1203210_0 WD-40 repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 454.0
HKD1_k127_1203210_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 415.0
HKD1_k127_1203210_10 - - - - 0.0000000000000000000000404 106.0
HKD1_k127_1203210_11 WD domain, G-beta repeat - - - 0.0000000000000000006287 102.0
HKD1_k127_1203210_12 AAA ATPase domain - - - 0.000001993 62.0
HKD1_k127_1203210_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 402.0
HKD1_k127_1203210_3 PFAM ComEC Rec2-related protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 394.0
HKD1_k127_1203210_4 methyltransferase activity K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000007854 175.0
HKD1_k127_1203210_5 - - - - 0.000000000000000000000000000000000004447 140.0
HKD1_k127_1203210_7 GYD domain - - - 0.000000000000000000000000001648 114.0
HKD1_k127_1203210_8 WD-40 repeat - - - 0.0000000000000000000000001483 124.0
HKD1_k127_1203210_9 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000003417 107.0
HKD1_k127_1330535_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.083e-288 893.0
HKD1_k127_1330535_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.998e-286 916.0
HKD1_k127_1330535_10 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003079 265.0
HKD1_k127_1330535_11 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000004196 233.0
HKD1_k127_1330535_12 exodeoxyribonuclease I activity - - - 0.0000000000000000000000000000000000000000000000000000000000000009781 225.0
HKD1_k127_1330535_13 involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.000000000000000000000000000000000000000000000000000000000000003543 230.0
HKD1_k127_1330535_14 Acyl-transferase - - - 0.00000000000000000000000000000000000000000000003414 179.0
HKD1_k127_1330535_15 PFAM Roadblock LC7 family protein K07131 - - 0.000000000000000000000000000000000000000000000703 170.0
HKD1_k127_1330535_16 PFAM Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000005981 174.0
HKD1_k127_1330535_17 PFAM phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000001661 135.0
HKD1_k127_1330535_18 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000373 128.0
HKD1_k127_1330535_19 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000008889 100.0
HKD1_k127_1330535_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.396e-239 744.0
HKD1_k127_1330535_20 - - - - 0.0000000009437 70.0
HKD1_k127_1330535_3 GTP-binding protein TypA K06207 - - 9.644e-211 676.0
HKD1_k127_1330535_4 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 542.0
HKD1_k127_1330535_5 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 424.0
HKD1_k127_1330535_6 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 349.0
HKD1_k127_1330535_7 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 308.0
HKD1_k127_1330535_8 SMART PDZ DHR GLGF domain protein K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 300.0
HKD1_k127_1330535_9 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007797 278.0
HKD1_k127_134772_0 Belongs to the formate--tetrahydrofolate ligase family K00288,K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 2.834e-319 987.0
HKD1_k127_134772_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 4.518e-282 878.0
HKD1_k127_134772_2 ABC transporter transmembrane region K06147 - - 2.842e-255 802.0
HKD1_k127_134772_3 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 571.0
HKD1_k127_134772_4 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 476.0
HKD1_k127_134772_5 Haloacid dehalogenase-like hydrolase - GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309 - 0.000000000000000000000000000000000000000000000000000001701 198.0
HKD1_k127_134772_6 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000000000000000000266 197.0
HKD1_k127_134772_7 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000000000000000006053 168.0
HKD1_k127_134772_8 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000002598 157.0
HKD1_k127_1353519_0 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 350.0
HKD1_k127_1353519_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 295.0
HKD1_k127_1353519_10 DMSO reductase anchor subunit (DmsC) K07308 - - 0.000000000008723 76.0
HKD1_k127_1353519_11 TIGRFAM bicupin, oxalate decarboxylase family K01569 - 4.1.1.2 0.0002104 48.0
HKD1_k127_1353519_2 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000145 267.0
HKD1_k127_1353519_3 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000004269 264.0
HKD1_k127_1353519_4 e3 binding domain K00658,K09699 GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.168,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000002013 261.0
HKD1_k127_1353519_5 Abc transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001275 249.0
HKD1_k127_1353519_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000003688 176.0
HKD1_k127_1353519_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000001099 162.0
HKD1_k127_1353519_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000004666 128.0
HKD1_k127_1353519_9 component of anaerobic dehydrogenases - - - 0.000000000000000000000000000001074 133.0
HKD1_k127_1384474_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 1.545e-237 739.0
HKD1_k127_1384474_1 Glycosyl hydrolase 36 superfamily, catalytic domain K00702 - 2.4.1.20 2.607e-201 644.0
HKD1_k127_1384474_2 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 8.843e-196 619.0
HKD1_k127_1384474_3 COG0038 Chloride channel protein EriC K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 602.0
HKD1_k127_1384474_4 PFAM IstB domain protein ATP-binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 508.0
HKD1_k127_1384474_5 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 301.0
HKD1_k127_1384474_6 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000001549 224.0
HKD1_k127_1384474_7 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000004819 216.0
HKD1_k127_1384474_8 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000001153 179.0
HKD1_k127_1384474_9 TIGRFAM primosome, DnaD subunit - - - 0.00000000000000000000000000000001096 137.0
HKD1_k127_14861_0 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 359.0
HKD1_k127_14861_1 4-phosphoerythronate dehydrogenase activity K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 338.0
HKD1_k127_14861_2 Protein of unknown function DUF115 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 316.0
HKD1_k127_14861_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000001675 115.0
HKD1_k127_1539698_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 3.558e-313 975.0
HKD1_k127_1539698_1 Heat shock 70 kDa protein K04043 - - 3.293e-292 908.0
HKD1_k127_1539698_10 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 502.0
HKD1_k127_1539698_11 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 466.0
HKD1_k127_1539698_12 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 468.0
HKD1_k127_1539698_13 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 461.0
HKD1_k127_1539698_14 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 439.0
HKD1_k127_1539698_15 peptidase M29 aminopeptidase II K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 416.0
HKD1_k127_1539698_16 Domain of unknown function (DUF3390) K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 402.0
HKD1_k127_1539698_17 spermidine synthase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 354.0
HKD1_k127_1539698_18 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 326.0
HKD1_k127_1539698_19 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 316.0
HKD1_k127_1539698_2 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 3.376e-278 872.0
HKD1_k127_1539698_20 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008925 268.0
HKD1_k127_1539698_21 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000006013 255.0
HKD1_k127_1539698_22 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000003487 168.0
HKD1_k127_1539698_24 NUDIX domain - - - 0.00000000000000000000000000008624 121.0
HKD1_k127_1539698_25 Protein of unknown function (DUF952) K00799 - 2.5.1.18 0.000000000000000000000000484 119.0
HKD1_k127_1539698_26 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000005645 106.0
HKD1_k127_1539698_27 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000001304 110.0
HKD1_k127_1539698_28 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000001291 98.0
HKD1_k127_1539698_3 ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD K16013 - - 1.022e-261 847.0
HKD1_k127_1539698_4 VWA domain containing CoxE-like protein K07114 - - 1.428e-240 767.0
HKD1_k127_1539698_5 oxidase, subunit K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 546.0
HKD1_k127_1539698_6 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 522.0
HKD1_k127_1539698_7 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 507.0
HKD1_k127_1539698_8 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 495.0
HKD1_k127_1539698_9 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 494.0
HKD1_k127_157484_0 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 512.0
HKD1_k127_157484_1 histidine kinase HAMP region domain protein K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 426.0
HKD1_k127_157484_10 Domain of unknown function (DUF4440) - - - 0.0007022 51.0
HKD1_k127_157484_2 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K08070 - 1.3.1.74,3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005646 378.0
HKD1_k127_157484_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 330.0
HKD1_k127_157484_4 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 286.0
HKD1_k127_157484_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003333 279.0
HKD1_k127_157484_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004158 259.0
HKD1_k127_157484_7 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000001927 236.0
HKD1_k127_157484_8 lipolytic protein G-D-S-L family - - - 0.000009038 57.0
HKD1_k127_157484_9 von Willebrand factor, type A K07114 - - 0.00004131 49.0
HKD1_k127_1592068_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 9.035e-210 655.0
HKD1_k127_1592068_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 524.0
HKD1_k127_1592068_2 COGs COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 418.0
HKD1_k127_1687259_0 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 592.0
HKD1_k127_1687259_1 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 493.0
HKD1_k127_1687259_10 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000002017 149.0
HKD1_k127_1687259_11 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000001531 134.0
HKD1_k127_1687259_12 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000009716 121.0
HKD1_k127_1687259_13 DNA-binding transcription factor activity - - - 0.000000000000000000002009 100.0
HKD1_k127_1687259_15 PFAM Integrase core domain K07497 - - 0.0000000000000001463 80.0
HKD1_k127_1687259_16 Lysin motif - - - 0.00000008271 63.0
HKD1_k127_1687259_17 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00003415 57.0
HKD1_k127_1687259_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 452.0
HKD1_k127_1687259_3 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 401.0
HKD1_k127_1687259_4 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 379.0
HKD1_k127_1687259_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 339.0
HKD1_k127_1687259_6 TIGRFAM DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000007481 211.0
HKD1_k127_1687259_7 protein domain associated with - - - 0.0000000000000000000000000000000000000000000000008975 191.0
HKD1_k127_1687259_8 - - - - 0.000000000000000000000000000000000000000000005226 169.0
HKD1_k127_1687259_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000004241 154.0
HKD1_k127_1688375_0 Glycogen debranching enzyme - - - 0.0 1449.0
HKD1_k127_1688375_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.614e-215 681.0
HKD1_k127_1688375_10 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000007918 208.0
HKD1_k127_1688375_11 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000001375 160.0
HKD1_k127_1688375_12 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000003831 158.0
HKD1_k127_1688375_13 acid phosphatase activity K01077 - 3.1.3.1 0.000000000000000000000000000000001731 143.0
HKD1_k127_1688375_14 Transposase IS200 like - - - 0.000000000000000000000000009001 118.0
HKD1_k127_1688375_15 Hydrogenase maturation protease K08315 - 3.4.23.51 0.0000000000000001281 85.0
HKD1_k127_1688375_16 PFAM Integrase core domain K07497 - - 0.0000000000000001463 80.0
HKD1_k127_1688375_17 Oligoendopeptidase f K01283,K08602 - 3.4.15.1 0.00000000000008406 84.0
HKD1_k127_1688375_2 Alpha amylase, catalytic domain - - - 4.033e-213 671.0
HKD1_k127_1688375_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 540.0
HKD1_k127_1688375_4 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 404.0
HKD1_k127_1688375_5 PFAM ABC-3 protein K09816,K09819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 372.0
HKD1_k127_1688375_6 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 338.0
HKD1_k127_1688375_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 289.0
HKD1_k127_1688375_8 Zinc-uptake complex component A periplasmic K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000011 282.0
HKD1_k127_1688375_9 PFAM ABC transporter related K09820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008353 251.0
HKD1_k127_1710905_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2045.0
HKD1_k127_1710905_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1062.0
HKD1_k127_1710905_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000001691 59.0
HKD1_k127_1710905_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 4.342e-229 712.0
HKD1_k127_1710905_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 327.0
HKD1_k127_1710905_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009666 327.0
HKD1_k127_1710905_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000004893 229.0
HKD1_k127_1710905_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001347 226.0
HKD1_k127_1710905_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001487 219.0
HKD1_k127_1710905_8 YhhN family - - - 0.0000000000000000000000007456 112.0
HKD1_k127_1710905_9 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000126 103.0
HKD1_k127_185331_0 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.000000000000000000000000000000008874 138.0
HKD1_k127_185331_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000001603 94.0
HKD1_k127_185331_2 PFAM blue (type 1) copper domain protein - - - 0.0000004024 52.0
HKD1_k127_185331_3 Phage integrase family - - - 0.00000214 54.0
HKD1_k127_2013471_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 598.0
HKD1_k127_2013471_1 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 578.0
HKD1_k127_2013471_10 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 402.0
HKD1_k127_2013471_11 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 406.0
HKD1_k127_2013471_12 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 360.0
HKD1_k127_2013471_13 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 312.0
HKD1_k127_2013471_14 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 308.0
HKD1_k127_2013471_15 PFAM GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002079 282.0
HKD1_k127_2013471_16 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000000000000000000000000000002021 234.0
HKD1_k127_2013471_17 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000002239 235.0
HKD1_k127_2013471_18 PFAM tRNA rRNA methyltransferase (SpoU) K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000002777 232.0
HKD1_k127_2013471_19 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000001424 220.0
HKD1_k127_2013471_2 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 562.0
HKD1_k127_2013471_20 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000002281 209.0
HKD1_k127_2013471_21 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000008067 194.0
HKD1_k127_2013471_22 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000004145 184.0
HKD1_k127_2013471_23 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000001279 184.0
HKD1_k127_2013471_24 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000001741 191.0
HKD1_k127_2013471_25 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000000000006611 164.0
HKD1_k127_2013471_26 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000009233 160.0
HKD1_k127_2013471_27 major facilitator superfamily domain-containing protein - - - 0.00000000000000000000000000000000000002078 158.0
HKD1_k127_2013471_28 bacterial-type flagellum-dependent swarming motility - - - 0.00000000000000000000000000000000001646 152.0
HKD1_k127_2013471_29 - - - - 0.000000000000000000000000000000008284 131.0
HKD1_k127_2013471_3 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 556.0
HKD1_k127_2013471_30 - - - - 0.0000000000000000000000000001055 121.0
HKD1_k127_2013471_31 - - - - 0.0000000000000000003547 99.0
HKD1_k127_2013471_32 - K03686 - - 0.000000000000006194 77.0
HKD1_k127_2013471_33 - - - - 0.0000000000009018 70.0
HKD1_k127_2013471_34 Acetyltransferase (GNAT) domain - - - 0.000000000103 72.0
HKD1_k127_2013471_35 Isoprenylcysteine carboxyl methyltransferase - - - 0.000000001609 66.0
HKD1_k127_2013471_36 Domain of unknown function (DU1801) - - - 0.000000007498 62.0
HKD1_k127_2013471_37 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000001839 62.0
HKD1_k127_2013471_39 lactoylglutathione lyase activity - - - 0.000001192 57.0
HKD1_k127_2013471_4 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 523.0
HKD1_k127_2013471_40 WD40-like Beta Propeller Repeat K03641 - - 0.0004141 53.0
HKD1_k127_2013471_5 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 513.0
HKD1_k127_2013471_6 (2R)-phospho-3-sulfolactate synthase (ComA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 454.0
HKD1_k127_2013471_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 451.0
HKD1_k127_2013471_8 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 433.0
HKD1_k127_2013471_9 Major facilitator Superfamily K08217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 423.0
HKD1_k127_202032_0 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 535.0
HKD1_k127_202032_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 528.0
HKD1_k127_202032_10 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000005799 184.0
HKD1_k127_202032_11 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000339 164.0
HKD1_k127_202032_12 DGC domain - - - 0.00000000000000000000000000000000009844 142.0
HKD1_k127_202032_13 PFAM regulatory protein, ArsR K03892 - - 0.0000000000000000000000000000000003524 135.0
HKD1_k127_202032_14 OsmC-like protein - - - 0.0000000000000000000000000000000006826 136.0
HKD1_k127_202032_15 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000002201 125.0
HKD1_k127_202032_16 Radical SAM - - - 0.000000000000000000000000000007295 124.0
HKD1_k127_202032_17 Putative Fe-S cluster - - - 0.00000000000000000000000003381 115.0
HKD1_k127_202032_18 TIGRFAM redox-active disulfide protein 2 - - - 0.00000000000000000000000005507 109.0
HKD1_k127_202032_19 DGC domain - - - 0.000000000000000000000005012 106.0
HKD1_k127_202032_2 3-demethylubiquinone-9 3-O-methyltransferase activity K06219 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 355.0
HKD1_k127_202032_20 - - - - 0.0000000000001247 76.0
HKD1_k127_202032_21 cell redox homeostasis - - - 0.0000872 50.0
HKD1_k127_202032_3 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 293.0
HKD1_k127_202032_4 PFAM amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 293.0
HKD1_k127_202032_5 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007146 293.0
HKD1_k127_202032_6 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000008573 258.0
HKD1_k127_202032_7 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000002619 203.0
HKD1_k127_202032_8 - - - - 0.0000000000000000000000000000000000000000000000000009914 191.0
HKD1_k127_202032_9 IA, variant 3 K07025 - - 0.00000000000000000000000000000000000000000000000004106 186.0
HKD1_k127_207381_0 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 9.665e-197 624.0
HKD1_k127_207381_1 PFAM amidohydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 556.0
HKD1_k127_207381_2 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 475.0
HKD1_k127_207381_3 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 364.0
HKD1_k127_207381_4 Dehydrogenase K00248,K00249,K20035 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0052890,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007939 317.0
HKD1_k127_207381_5 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 298.0
HKD1_k127_207381_6 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000004847 231.0
HKD1_k127_207381_7 transcriptional - - - 0.00000000000000000000001097 106.0
HKD1_k127_207381_8 lactoylglutathione lyase activity - - - 0.00000000000000000000002374 104.0
HKD1_k127_207381_9 response regulator - - - 0.000000001079 63.0
HKD1_k127_2085475_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 570.0
HKD1_k127_2085475_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 407.0
HKD1_k127_2085475_10 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000000001129 102.0
HKD1_k127_2085475_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00006777 50.0
HKD1_k127_2085475_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 406.0
HKD1_k127_2085475_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 383.0
HKD1_k127_2085475_4 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005744 296.0
HKD1_k127_2085475_5 K00059 3-oxoacyl- acyl-carrier protein reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 265.0
HKD1_k127_2085475_6 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000003083 263.0
HKD1_k127_2085475_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000006465 215.0
HKD1_k127_2085475_8 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000001088 189.0
HKD1_k127_2085475_9 Asp23 family, cell envelope-related function - - - 0.000000000000000000000000000003844 123.0
HKD1_k127_2119843_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 561.0
HKD1_k127_2119843_1 multicopper oxidases K06324 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0052716,GO:0055114 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 582.0
HKD1_k127_2119843_10 -O-antigen K02847 - - 0.000000000000000000000000000000000000000000000002963 188.0
HKD1_k127_2119843_11 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000477 171.0
HKD1_k127_2119843_12 - - - - 0.000000000000000000000000000000000000001237 154.0
HKD1_k127_2119843_13 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000002026 158.0
HKD1_k127_2119843_14 PFAM HD domain - - - 0.0000000000000000000000000000194 136.0
HKD1_k127_2119843_15 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000125 118.0
HKD1_k127_2119843_16 integral membrane protein - - - 0.0000000000000000005462 92.0
HKD1_k127_2119843_17 - - - - 0.000000000000002993 81.0
HKD1_k127_2119843_18 Glycosyltransferase Family 4 - - - 0.000000000000007323 76.0
HKD1_k127_2119843_19 Transglycosylase associated protein - - - 0.0000000000008283 71.0
HKD1_k127_2119843_2 PFAM Glycosyl transferase, group 1 K03208 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 479.0
HKD1_k127_2119843_20 Peptidase m28 - - - 0.0000000008559 69.0
HKD1_k127_2119843_21 Belongs to the UPF0337 (CsbD) family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000001069 53.0
HKD1_k127_2119843_22 Belongs to the UPF0337 (CsbD) family - - - 0.000002617 53.0
HKD1_k127_2119843_23 Bacterial Ig-like domain - - - 0.00007202 54.0
HKD1_k127_2119843_24 response regulator receiver - - - 0.0004302 48.0
HKD1_k127_2119843_3 PFAM NAD dependent epimerase dehydratase family K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 424.0
HKD1_k127_2119843_4 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 424.0
HKD1_k127_2119843_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 298.0
HKD1_k127_2119843_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003486 253.0
HKD1_k127_2119843_7 PFAM Signal transduction response regulator, receiver region - - - 0.00000000000000000000000000000000000000000000000000000000000000000001091 239.0
HKD1_k127_2119843_8 - - - - 0.0000000000000000000000000000000000000000000000000000000009904 206.0
HKD1_k127_2119843_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000007907 196.0
HKD1_k127_2133952_0 lipid-A-disaccharide synthase activity K00748 - 2.4.1.182 4.23e-205 652.0
HKD1_k127_2133952_1 teichoic acid transport K01990,K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 614.0
HKD1_k127_2133952_2 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 406.0
HKD1_k127_2133952_3 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 316.0
HKD1_k127_2133952_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 308.0
HKD1_k127_2147898_0 PNKP adenylyltransferase domain, ligase domain K01090 - 3.1.3.16 0.0 1226.0
HKD1_k127_2147898_1 RNA repair, ligase-Pnkp-associating, region of Hen1 - - - 5.447e-202 638.0
HKD1_k127_2147898_10 Domain of unknown function (DUF4432) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 406.0
HKD1_k127_2147898_11 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 407.0
HKD1_k127_2147898_12 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 402.0
HKD1_k127_2147898_13 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 383.0
HKD1_k127_2147898_14 Uncharacterised ACR (DUF711) K09157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 368.0
HKD1_k127_2147898_15 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 356.0
HKD1_k127_2147898_16 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 342.0
HKD1_k127_2147898_17 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 338.0
HKD1_k127_2147898_18 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 324.0
HKD1_k127_2147898_19 Branched-chain amino acid transport system / permease component K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 321.0
HKD1_k127_2147898_2 Bacterial extracellular solute-binding protein - - - 4.281e-196 621.0
HKD1_k127_2147898_20 PFAM periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 315.0
HKD1_k127_2147898_21 Transketolase, central region K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 300.0
HKD1_k127_2147898_22 D-lyxose isomerase K09988 - 5.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001077 269.0
HKD1_k127_2147898_23 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000004158 269.0
HKD1_k127_2147898_24 helix_turn _helix lactose operon repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000187 265.0
HKD1_k127_2147898_25 Binding-protein-dependent transport systems inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006055 259.0
HKD1_k127_2147898_26 RbsD / FucU transport protein family K02431 - 5.1.3.29 0.00000000000000000000000000000000000000000000000000000000000001619 218.0
HKD1_k127_2147898_27 Bacterial extracellular solute-binding protein K02027,K10117 - - 0.000000000000000000000000000000000000000000000000000000000001773 226.0
HKD1_k127_2147898_28 PFAM carbohydrate kinase, FGGY K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000003667 226.0
HKD1_k127_2147898_29 Binding-protein-dependent transport system inner membrane component K10202 - - 0.00000000000000000000000000000000000000000000000000000000002828 216.0
HKD1_k127_2147898_3 Alpha mannosidase, middle domain K01191,K15524,K16869 GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564 2.3.1.204,3.2.1.170,3.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 626.0
HKD1_k127_2147898_30 Belongs to the ABC transporter superfamily K10823 - - 0.00000000000000000000000000000000000000000000000000000001889 203.0
HKD1_k127_2147898_31 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000002486 188.0
HKD1_k127_2147898_32 Short-chain dehydrogenase reductase sdr K00034 - 1.1.1.47 0.00000000000000000000000000000000000000000005915 170.0
HKD1_k127_2147898_33 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000004427 162.0
HKD1_k127_2147898_34 Cytidylyltransferase-like - - - 0.000000000000000000000000000000000001455 149.0
HKD1_k127_2147898_35 Asp/Glu/Hydantoin racemase - - - 0.00000000000000000000000000001666 128.0
HKD1_k127_2147898_36 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000003687 113.0
HKD1_k127_2147898_37 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.000000000000000000003801 107.0
HKD1_k127_2147898_38 Response regulator, receiver - - - 0.00000000000241 72.0
HKD1_k127_2147898_39 PFAM Isochorismatase - - - 0.00000000000943 75.0
HKD1_k127_2147898_4 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 604.0
HKD1_k127_2147898_40 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000007125 58.0
HKD1_k127_2147898_41 Binding-protein-dependent transport system inner membrane component - - - 0.00000436 52.0
HKD1_k127_2147898_5 ADP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 599.0
HKD1_k127_2147898_6 Glycosyl hydrolase family 63 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 560.0
HKD1_k127_2147898_7 Protein of unknown function (DUF2961) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 542.0
HKD1_k127_2147898_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 536.0
HKD1_k127_2147898_9 proline dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 439.0
HKD1_k127_2181691_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 406.0
HKD1_k127_2181691_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 336.0
HKD1_k127_2181691_2 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000001017 141.0
HKD1_k127_2181691_3 PFAM ABC-2 type transporter K01992 - - 0.0000002628 55.0
HKD1_k127_2185101_0 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 5.665e-292 914.0
HKD1_k127_2185101_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.345e-288 917.0
HKD1_k127_2185101_10 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 491.0
HKD1_k127_2185101_11 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 460.0
HKD1_k127_2185101_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 413.0
HKD1_k127_2185101_13 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 392.0
HKD1_k127_2185101_14 Predicted nucleotidyltransferase K07074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 367.0
HKD1_k127_2185101_15 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 365.0
HKD1_k127_2185101_16 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 348.0
HKD1_k127_2185101_17 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 344.0
HKD1_k127_2185101_18 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 311.0
HKD1_k127_2185101_19 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007519 275.0
HKD1_k127_2185101_2 Endoribonuclease that initiates mRNA decay K18682 - - 1.154e-224 706.0
HKD1_k127_2185101_20 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001425 267.0
HKD1_k127_2185101_21 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000007323 242.0
HKD1_k127_2185101_22 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000006919 241.0
HKD1_k127_2185101_23 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000002144 229.0
HKD1_k127_2185101_24 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000004451 239.0
HKD1_k127_2185101_25 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000002216 236.0
HKD1_k127_2185101_26 Predicted nucleotidyltransferase K07074 - - 0.000000000000000000000000000000000000000000000000000000000000007439 218.0
HKD1_k127_2185101_27 polysaccharide deacetylase K01406 - 3.4.24.40 0.0000000000000000000000000000000000000000000000000000000000001472 228.0
HKD1_k127_2185101_28 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000221 212.0
HKD1_k127_2185101_29 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000001177 208.0
HKD1_k127_2185101_3 Aminotransferase class-V - - - 5.976e-198 626.0
HKD1_k127_2185101_30 Extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000003717 211.0
HKD1_k127_2185101_31 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000557 196.0
HKD1_k127_2185101_33 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000000000007467 182.0
HKD1_k127_2185101_34 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000000000000000002603 187.0
HKD1_k127_2185101_35 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000007227 152.0
HKD1_k127_2185101_36 - - - - 0.00000000000000000000000000000000000000139 154.0
HKD1_k127_2185101_37 - - - - 0.000000000000000000000000000000000000003942 154.0
HKD1_k127_2185101_38 - - - - 0.00000000000000000000000000000000000008057 147.0
HKD1_k127_2185101_39 - - - - 0.00000000000000000000000000000003388 128.0
HKD1_k127_2185101_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 594.0
HKD1_k127_2185101_40 PFAM transcriptional regulator PadR family protein - - - 0.0000000000000000000000000000007701 128.0
HKD1_k127_2185101_42 Septum formation initiator - - - 0.000000000000003182 80.0
HKD1_k127_2185101_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 574.0
HKD1_k127_2185101_6 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 552.0
HKD1_k127_2185101_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 525.0
HKD1_k127_2185101_8 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 515.0
HKD1_k127_2185101_9 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 486.0
HKD1_k127_2200829_0 Glycosyltransferase 36 associated - - - 0.0 1362.0
HKD1_k127_2200829_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 8.64e-205 645.0
HKD1_k127_2200829_10 PFAM Vitamin K epoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000000000001568 228.0
HKD1_k127_2200829_11 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000001305 178.0
HKD1_k127_2200829_13 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000002117 154.0
HKD1_k127_2200829_14 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000009572 133.0
HKD1_k127_2200829_15 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000001724 128.0
HKD1_k127_2200829_16 Belongs to the UPF0109 family K06960 - - 0.00000000000000001126 84.0
HKD1_k127_2200829_17 LuxR family transcriptional regulator K07694,K11618 - - 0.000000003202 60.0
HKD1_k127_2200829_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 576.0
HKD1_k127_2200829_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 551.0
HKD1_k127_2200829_4 WD40 domain protein beta Propeller K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 480.0
HKD1_k127_2200829_5 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 444.0
HKD1_k127_2200829_6 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 421.0
HKD1_k127_2200829_7 heme binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 364.0
HKD1_k127_2200829_8 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 299.0
HKD1_k127_2200829_9 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 296.0
HKD1_k127_2214572_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1133.0
HKD1_k127_2214572_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 617.0
HKD1_k127_2214572_2 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 594.0
HKD1_k127_2214572_3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 391.0
HKD1_k127_2214572_4 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 330.0
HKD1_k127_2214572_5 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002274 255.0
HKD1_k127_2214572_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000009496 72.0
HKD1_k127_2248502_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 441.0
HKD1_k127_2248502_1 transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 375.0
HKD1_k127_2248502_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 326.0
HKD1_k127_2248502_3 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 302.0
HKD1_k127_2248502_4 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000005047 173.0
HKD1_k127_2248502_5 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000004651 140.0
HKD1_k127_2248502_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000007538 124.0
HKD1_k127_2248502_7 DUF218 domain - - - 0.0004528 48.0
HKD1_k127_2314605_0 nuclear chromosome segregation - - - 2.067e-270 856.0
HKD1_k127_2314605_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 1.43e-209 656.0
HKD1_k127_2314605_10 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 346.0
HKD1_k127_2314605_11 PFAM YbbR family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 337.0
HKD1_k127_2314605_12 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 342.0
HKD1_k127_2314605_13 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 289.0
HKD1_k127_2314605_14 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004549 279.0
HKD1_k127_2314605_15 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000002427 254.0
HKD1_k127_2314605_16 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000006362 235.0
HKD1_k127_2314605_17 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000004806 237.0
HKD1_k127_2314605_18 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000002668 238.0
HKD1_k127_2314605_19 PFAM phospholipase D Transphosphatidylase - - - 0.000000000000000000000000000000000000000000000000000000000003556 215.0
HKD1_k127_2314605_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 488.0
HKD1_k127_2314605_20 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000003668 207.0
HKD1_k127_2314605_21 Ig-like domain from next to BRCA1 gene K13276 - - 0.0000000000000000000000000000000000000000000003946 180.0
HKD1_k127_2314605_22 Transcriptional regulator K03724 - - 0.00000000000000000000000000000000000000000002417 168.0
HKD1_k127_2314605_23 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000007596 166.0
HKD1_k127_2314605_24 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000002367 171.0
HKD1_k127_2314605_25 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000001019 121.0
HKD1_k127_2314605_26 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000000000000003196 106.0
HKD1_k127_2314605_27 LysM domain K07273,K22278 - 3.5.1.104 0.00000000000000000000000094 113.0
HKD1_k127_2314605_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 446.0
HKD1_k127_2314605_30 PFAM HD domain - - - 0.0000000000000008652 85.0
HKD1_k127_2314605_31 Parallel beta-helix repeats - - - 0.00000004594 66.0
HKD1_k127_2314605_32 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0005285 46.0
HKD1_k127_2314605_4 Glycosyltransferase 28 domain K03715 - 2.4.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 415.0
HKD1_k127_2314605_5 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 406.0
HKD1_k127_2314605_6 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 398.0
HKD1_k127_2314605_7 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 398.0
HKD1_k127_2314605_8 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 349.0
HKD1_k127_2314605_9 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 345.0
HKD1_k127_2349674_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 1.388e-244 769.0
HKD1_k127_2349674_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 336.0
HKD1_k127_2349674_10 Belongs to the 'phage' integrase family K04763 - - 0.000007511 51.0
HKD1_k127_2349674_11 Resolvase - - - 0.00009787 45.0
HKD1_k127_2349674_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008401 287.0
HKD1_k127_2349674_3 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007177 235.0
HKD1_k127_2349674_4 OsmC-like protein K09136 - - 0.000000000000000000000000000000000000000000000000000004438 193.0
HKD1_k127_2349674_5 Domain of unknown function (DUF4332) - - - 0.000000000000000000000000000000000000000000000007392 176.0
HKD1_k127_2349674_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000001968 128.0
HKD1_k127_2349674_7 - - - - 0.0000000000000000000000003329 111.0
HKD1_k127_2349674_8 - - - - 0.00000000000000002087 85.0
HKD1_k127_2349674_9 ArsR family transcriptional regulator - - - 0.00000000008532 73.0
HKD1_k127_2354764_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 5.061e-242 766.0
HKD1_k127_2354764_1 dehydrogenase, E1 component K11381 - 1.2.4.4 2.756e-237 751.0
HKD1_k127_2354764_10 Dihydroorotate dehydrogenase K00226,K00254 - 1.3.5.2,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 304.0
HKD1_k127_2354764_11 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004043 286.0
HKD1_k127_2354764_12 PFAM DRTGG domain protein K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009084 275.0
HKD1_k127_2354764_13 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000000000000297 230.0
HKD1_k127_2354764_14 - - - - 0.00000000000000000000000000000000000000000000000000000001911 211.0
HKD1_k127_2354764_15 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000000000000001261 181.0
HKD1_k127_2354764_16 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000002308 172.0
HKD1_k127_2354764_17 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000001587 152.0
HKD1_k127_2354764_18 - - - - 0.00000000000000000000004674 109.0
HKD1_k127_2354764_19 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000004039 98.0
HKD1_k127_2354764_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 512.0
HKD1_k127_2354764_20 Wd repeat protein K14963 GO:0000228,GO:0000723,GO:0000785,GO:0000790,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006323,GO:0006325,GO:0006333,GO:0006338,GO:0006342,GO:0006348,GO:0006355,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008213,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010564,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016569,GO:0016570,GO:0016571,GO:0018022,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031497,GO:0031507,GO:0031974,GO:0031981,GO:0032200,GO:0032259,GO:0032991,GO:0034401,GO:0034641,GO:0034708,GO:0034968,GO:0035097,GO:0036211,GO:0040029,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0048188,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051276,GO:0051445,GO:0051568,GO:0051726,GO:0060249,GO:0060255,GO:0065007,GO:0065008,GO:0070013,GO:0070828,GO:0070868,GO:0070869,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097549,GO:1901360,GO:1901564,GO:1902494,GO:1902679,GO:1903341,GO:1903506,GO:1903507,GO:1990234,GO:2000112,GO:2000113,GO:2000241,GO:2001141 - 0.000000000000001031 93.0
HKD1_k127_2354764_21 - - - - 0.000000000000001483 89.0
HKD1_k127_2354764_22 PspC domain K03973 - - 0.0000000000001565 72.0
HKD1_k127_2354764_23 - - - - 0.000000000006545 70.0
HKD1_k127_2354764_24 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000001365 66.0
HKD1_k127_2354764_25 Transposase IS200 like - - - 0.00002533 48.0
HKD1_k127_2354764_26 Belongs to the ABC transporter superfamily K11084 - - 0.0006591 45.0
HKD1_k127_2354764_27 - - - - 0.0008503 49.0
HKD1_k127_2354764_3 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 514.0
HKD1_k127_2354764_4 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K11540 GO:0000050,GO:0000166,GO:0002119,GO:0002164,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006807,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009653,GO:0009791,GO:0009887,GO:0009987,GO:0016053,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019627,GO:0019752,GO:0019856,GO:0022612,GO:0030554,GO:0031406,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035295,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046394,GO:0046483,GO:0048513,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0055086,GO:0055123,GO:0060465,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1905905 2.1.3.2,3.5.2.3,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 460.0
HKD1_k127_2354764_5 Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase K01591,K13421 - 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 437.0
HKD1_k127_2354764_6 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity K01954,K01955,K03660,K11540,K11541,K19656 GO:0000050,GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003922,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004518,GO:0004519,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006142,GO:0006206,GO:0006207,GO:0006220,GO:0006244,GO:0006259,GO:0006281,GO:0006282,GO:0006284,GO:0006285,GO:0006289,GO:0006304,GO:0006355,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0008652,GO:0009056,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009166,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009889,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010605,GO:0016020,GO:0016021,GO:0016053,GO:0016363,GO:0016604,GO:0016607,GO:0016740,GO:0016741,GO:0016743,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019104,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019627,GO:0019637,GO:0019692,GO:0019752,GO:0019856,GO:0031224,GO:0031323,GO:0031324,GO:0031326,GO:0031974,GO:0031981,GO:0032356,GO:0032357,GO:0032991,GO:0033554,GO:0033683,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045007,GO:0045008,GO:0045738,GO:0045934,GO:0045984,GO:0046112,GO:0046386,GO:0046394,GO:0046434,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0051716,GO:0055086,GO:0060255,GO:0062012,GO:0062014,GO:0065007,GO:0070013,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0072529,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901135,GO:1901136,GO:1901291,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2000779,GO:2000780,GO:2001020,GO:2001021,GO:2001141 2.1.3.2,3.5.2.3,4.2.99.18,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 412.0
HKD1_k127_2354764_7 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 379.0
HKD1_k127_2354764_8 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 338.0
HKD1_k127_2354764_9 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 337.0
HKD1_k127_2362493_0 PFAM CheR methyltransferase, SAM binding domain K00575,K13924 - 2.1.1.80,3.1.1.61 1.007e-223 709.0
HKD1_k127_2362493_1 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 458.0
HKD1_k127_2362493_10 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000002516 94.0
HKD1_k127_2362493_11 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.0000000000000001814 85.0
HKD1_k127_2362493_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 398.0
HKD1_k127_2362493_3 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 384.0
HKD1_k127_2362493_4 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 355.0
HKD1_k127_2362493_5 PFAM CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005469 272.0
HKD1_k127_2362493_6 NAD synthase K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000004495 205.0
HKD1_k127_2362493_7 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000001819 208.0
HKD1_k127_2362493_8 - K07403 - - 0.0000000000000000000000000000000000000000001489 166.0
HKD1_k127_2362493_9 lipoprotein biosynthetic process K13292 - - 0.00000000000000000000000000000000006762 142.0
HKD1_k127_250102_0 ABC transporter transmembrane region - - - 9.703e-239 753.0
HKD1_k127_250102_1 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 8.134e-228 714.0
HKD1_k127_250102_10 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05827,K05844 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000000007342 227.0
HKD1_k127_250102_11 Aminoglycoside-2''-adenylyltransferase K19545 - - 0.000000000000000000000000000000000000000000000000000000000004715 212.0
HKD1_k127_250102_12 virulence factor implicated in the pathogenesis of mycobacterium tuberculosis at the level of intracellular survival, by the alteration of cell signaling events or by direct cytotoxicity catalytic activity a phosphatidylcholine H(2)O 1,2- diacylglycerol choline phosphate K01114 GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006629,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009405,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0034480,GO:0035821,GO:0042578,GO:0044003,GO:0044238,GO:0044403,GO:0044419,GO:0044464,GO:0051701,GO:0051704,GO:0051817,GO:0052008,GO:0052043,GO:0052111,GO:0052185,GO:0052188,GO:0052368,GO:0071704,GO:0071944,GO:1901575 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000002001 221.0
HKD1_k127_250102_13 - - - - 0.00000000000000000000000000000000000000000000000000000004696 208.0
HKD1_k127_250102_14 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000009059 192.0
HKD1_k127_250102_15 - - - - 0.00000000000000000000000000000000000000000000000000009608 191.0
HKD1_k127_250102_16 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000002182 188.0
HKD1_k127_250102_17 FMN binding - - - 0.0000000000000000000000000000000000000000001704 163.0
HKD1_k127_250102_18 PFAM phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000000006279 169.0
HKD1_k127_250102_2 (ABC) transporter K06147 - - 2.855e-216 686.0
HKD1_k127_250102_20 PFAM phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000001914 153.0
HKD1_k127_250102_21 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000003728 152.0
HKD1_k127_250102_22 Methyltransferase domain - - - 0.00000000000000000000000000000001408 133.0
HKD1_k127_250102_23 SnoaL-like domain - - - 0.000000000000000000000000001317 123.0
HKD1_k127_250102_24 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000009725 117.0
HKD1_k127_250102_25 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000002916 104.0
HKD1_k127_250102_26 Acetyltransferase (GNAT) family - - - 0.000000000000000000002768 101.0
HKD1_k127_250102_27 Adenylate Guanylate cyclase - - - 0.0000000000000006402 93.0
HKD1_k127_250102_28 - - - - 0.000000000000003016 79.0
HKD1_k127_250102_29 GNAT acetyltransferase - - - 0.00000000002576 74.0
HKD1_k127_250102_3 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 471.0
HKD1_k127_250102_30 GAF domain - - - 0.00000000003202 73.0
HKD1_k127_250102_31 - - - - 0.00000000109 69.0
HKD1_k127_250102_33 SPFH domain Band 7 family protein 2 - - - 0.0004157 50.0
HKD1_k127_250102_34 - - - - 0.0006664 49.0
HKD1_k127_250102_35 Histidine kinase - - - 0.0007327 51.0
HKD1_k127_250102_4 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 468.0
HKD1_k127_250102_5 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 397.0
HKD1_k127_250102_6 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 408.0
HKD1_k127_250102_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 359.0
HKD1_k127_250102_8 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 292.0
HKD1_k127_250102_9 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000573 246.0
HKD1_k127_25210_0 PBP superfamily domain K03750,K07219 - 2.10.1.1 4.428e-279 872.0
HKD1_k127_25210_1 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 1.567e-204 641.0
HKD1_k127_25210_10 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 358.0
HKD1_k127_25210_11 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 342.0
HKD1_k127_25210_12 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 332.0
HKD1_k127_25210_13 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 303.0
HKD1_k127_25210_14 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 303.0
HKD1_k127_25210_15 domain protein K02674,K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 310.0
HKD1_k127_25210_16 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001168 308.0
HKD1_k127_25210_17 PFAM Glycoside hydrolase, family 16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001059 302.0
HKD1_k127_25210_18 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001131 282.0
HKD1_k127_25210_19 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000009664 239.0
HKD1_k127_25210_2 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 3.8e-203 639.0
HKD1_k127_25210_20 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000003555 234.0
HKD1_k127_25210_21 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000003807 236.0
HKD1_k127_25210_22 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000001933 227.0
HKD1_k127_25210_23 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000006131 209.0
HKD1_k127_25210_24 response regulator K07669 - - 0.000000000000000000000000000000000000000000000000008477 187.0
HKD1_k127_25210_25 COG0784 FOG CheY-like receiver - - - 0.00000000000000000000000000000000000000000000000001485 186.0
HKD1_k127_25210_26 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000001053 190.0
HKD1_k127_25210_27 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000543 176.0
HKD1_k127_25210_28 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000002301 148.0
HKD1_k127_25210_29 response regulator K07669 - - 0.0000000000000000000000000000000009708 139.0
HKD1_k127_25210_3 Bacterial pre-peptidase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 523.0
HKD1_k127_25210_30 photoreceptor activity - - - 0.00000000000000000000000000006795 134.0
HKD1_k127_25210_31 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000002698 114.0
HKD1_k127_25210_32 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07777 - 2.7.13.3 0.000000000000000000002315 110.0
HKD1_k127_25210_33 CAAX protease self-immunity K07052 - - 0.00000000000000000003984 100.0
HKD1_k127_25210_34 - - - - 0.00000001343 60.0
HKD1_k127_25210_4 phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 473.0
HKD1_k127_25210_5 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 433.0
HKD1_k127_25210_6 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 432.0
HKD1_k127_25210_7 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 426.0
HKD1_k127_25210_8 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 366.0
HKD1_k127_25210_9 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 342.0
HKD1_k127_255394_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.368e-214 681.0
HKD1_k127_255394_1 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 6.314e-195 646.0
HKD1_k127_255394_2 Conserved repeat domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 343.0
HKD1_k127_255394_3 SnoaL-like domain - - - 0.000000000000000000000000000002683 123.0
HKD1_k127_255394_4 - - - - 0.000000000000002667 82.0
HKD1_k127_2559103_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.181e-234 738.0
HKD1_k127_2559103_1 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 1.226e-210 678.0
HKD1_k127_2559103_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 401.0
HKD1_k127_2559103_3 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 407.0
HKD1_k127_2559103_4 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000001133 266.0
HKD1_k127_2559103_5 PFAM Maf family protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000005061 216.0
HKD1_k127_2559103_6 - - - - 0.0000000000000000000000000000000000000000000002274 177.0
HKD1_k127_2559103_7 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000002843 141.0
HKD1_k127_264095_0 Cation transporting ATPase, C-terminus K01531 - 3.6.3.2 0.0 1056.0
HKD1_k127_264095_1 Belongs to the peptidase S16 family - - - 2.846e-259 822.0
HKD1_k127_264095_2 PFAM natural resistance-associated macrophage protein K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 558.0
HKD1_k127_264095_3 Melibiase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000009217 285.0
HKD1_k127_264095_4 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001229 258.0
HKD1_k127_264095_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000001046 130.0
HKD1_k127_264095_6 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000001792 91.0
HKD1_k127_264095_8 Tricorn protease homolog K08676 - - 0.00004823 55.0
HKD1_k127_2691133_0 amino acid transport K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 385.0
HKD1_k127_2691133_1 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 302.0
HKD1_k127_2691133_2 PFAM Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 293.0
HKD1_k127_2691133_3 ABC transporter, ATP-binding protein K10010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003521 281.0
HKD1_k127_2691133_4 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000009222 65.0
HKD1_k127_2691133_5 metallochaperone-like domain K17686 - 3.6.3.54 0.00008068 48.0
HKD1_k127_27179_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 3.469e-194 622.0
HKD1_k127_27179_1 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 561.0
HKD1_k127_27179_11 Histone acetyltransferase - - - 0.000000000000000000000000000000000000001964 152.0
HKD1_k127_27179_13 Flp pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000832 129.0
HKD1_k127_27179_14 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000009198 112.0
HKD1_k127_27179_15 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000001476 87.0
HKD1_k127_27179_16 TadE-like protein - - - 0.00000000004086 69.0
HKD1_k127_27179_17 - - - - 0.00000000009322 67.0
HKD1_k127_27179_18 PFAM TadE family protein - - - 0.0000000002904 67.0
HKD1_k127_27179_19 Gram-negative-bacterium-type cell wall biogenesis - - - 0.00000008338 58.0
HKD1_k127_27179_2 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 427.0
HKD1_k127_27179_21 Ami_2 K00788,K01447,K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 2.5.1.3,3.5.1.28 0.00006619 55.0
HKD1_k127_27179_3 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 336.0
HKD1_k127_27179_4 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000005818 235.0
HKD1_k127_27179_5 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000000000000000000000000000000000000000008799 215.0
HKD1_k127_27179_6 HD domain - - - 0.00000000000000000000000000000000000000000000000000005391 194.0
HKD1_k127_27179_7 PFAM response regulator receiver K02282 - - 0.00000000000000000000000000000000000000000000000004146 194.0
HKD1_k127_27179_8 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000000000000000000000000000111 181.0
HKD1_k127_27179_9 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000004294 161.0
HKD1_k127_2743348_0 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 593.0
HKD1_k127_2743348_1 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 518.0
HKD1_k127_2743348_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000001631 163.0
HKD1_k127_2743348_3 TIGRFAM cysteine desulfurase family protein - - - 0.000000000000000000000000000000000000006997 148.0
HKD1_k127_2743348_4 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.000000000000000000000000000003241 123.0
HKD1_k127_2743348_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00002387 48.0
HKD1_k127_2743348_6 - - - - 0.000213 46.0
HKD1_k127_2802505_0 carbohydrate binding K00702 - 2.4.1.20 0.0 1223.0
HKD1_k127_2802505_1 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0 1054.0
HKD1_k127_2802505_10 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000007304 226.0
HKD1_k127_2802505_11 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000004674 237.0
HKD1_k127_2802505_12 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000001167 217.0
HKD1_k127_2802505_13 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000001038 179.0
HKD1_k127_2802505_14 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000001223 160.0
HKD1_k127_2802505_15 Protein of unknown function (DUF1641) - - - 0.00000000000000000000000000000000000000211 155.0
HKD1_k127_2802505_16 Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source - - - 0.00000000000000000000000000000000005734 138.0
HKD1_k127_2802505_17 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000005322 124.0
HKD1_k127_2802505_18 - - - - 0.00000000000000000000002486 105.0
HKD1_k127_2802505_2 glycoside hydrolase family 2 sugar binding K01192 - 3.2.1.25 8.84e-322 1010.0
HKD1_k127_2802505_3 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 1.593e-224 705.0
HKD1_k127_2802505_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 606.0
HKD1_k127_2802505_5 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 545.0
HKD1_k127_2802505_6 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 516.0
HKD1_k127_2802505_7 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 457.0
HKD1_k127_2802505_8 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 352.0
HKD1_k127_2802505_9 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002257 256.0
HKD1_k127_2816841_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000744 477.0
HKD1_k127_2816841_1 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 462.0
HKD1_k127_2816841_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000004675 100.0
HKD1_k127_2844643_0 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008835 276.0
HKD1_k127_2844643_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007182 251.0
HKD1_k127_2844643_2 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000000000000000000000009725 184.0
HKD1_k127_2844643_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000006431 143.0
HKD1_k127_2844643_5 formate C-acetyltransferase activity K20038 GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006576,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009987,GO:0016829,GO:0016840,GO:0019695,GO:0033265,GO:0034641,GO:0042133,GO:0042135,GO:0042165,GO:0042402,GO:0042426,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0044248,GO:0046983,GO:0065007,GO:0065008,GO:0070405,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 4.3.99.4 0.0000000006814 60.0
HKD1_k127_2844643_6 Alpha beta hydrolase - - - 0.00003926 48.0
HKD1_k127_288235_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1341.0
HKD1_k127_288235_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 517.0
HKD1_k127_294402_0 PFAM type II secretion system protein K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 348.0
HKD1_k127_294402_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003698 271.0
HKD1_k127_294402_2 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000649 251.0
HKD1_k127_294402_3 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000000000000000000000001227 236.0
HKD1_k127_294402_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000004596 201.0
HKD1_k127_294402_5 competence protein - - - 0.00000000000000000000000000000000000000000000000000000001015 206.0
HKD1_k127_294402_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000006667 124.0
HKD1_k127_294402_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000004581 112.0
HKD1_k127_294402_8 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.00000000000000000000000007406 111.0
HKD1_k127_295357_0 Extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 595.0
HKD1_k127_295357_1 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 449.0
HKD1_k127_295357_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 392.0
HKD1_k127_295357_3 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000005803 123.0
HKD1_k127_295357_4 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000004445 66.0
HKD1_k127_29614_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 5.375e-289 908.0
HKD1_k127_29614_1 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 522.0
HKD1_k127_29614_2 saccharopine dehydrogenase activity K19064 - 1.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 432.0
HKD1_k127_29614_3 ABC-2 type transporter K01992 - - 0.0008138 45.0
HKD1_k127_3033910_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 1.651e-254 796.0
HKD1_k127_3033910_2 YacP-like NYN domain K06962 - - 0.000000000000000000000000001058 119.0
HKD1_k127_3045889_0 succinyl-diaminopimelate desuccinylase activity K01439 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.0 1179.0
HKD1_k127_3045889_1 Belongs to the SEDS family - - - 5.122e-214 694.0
HKD1_k127_3045889_10 amine dehydrogenase activity - - - 0.0000002572 61.0
HKD1_k127_3045889_11 Domain of unknown function DUF11 - - - 0.00006789 49.0
HKD1_k127_3045889_2 Aminotransferase K00812 - 2.6.1.1 6.724e-199 628.0
HKD1_k127_3045889_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 381.0
HKD1_k127_3045889_4 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000005564 226.0
HKD1_k127_3045889_5 membrane - - - 0.00000000000000000000000000000000000000000000042 177.0
HKD1_k127_3045889_6 PadR family transcriptional regulator - - - 0.00000000000000000000000000001762 121.0
HKD1_k127_3045889_7 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000005561 124.0
HKD1_k127_3045889_8 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000008093 123.0
HKD1_k127_3045889_9 - - - - 0.0000000000002832 81.0
HKD1_k127_3094829_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0 1557.0
HKD1_k127_3094829_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.052e-308 953.0
HKD1_k127_3094829_10 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001271 257.0
HKD1_k127_3094829_11 PFAM aspartate glutamate uridylate kinase K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000007791 254.0
HKD1_k127_3094829_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000006461 153.0
HKD1_k127_3094829_13 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000009356 147.0
HKD1_k127_3094829_14 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000003578 117.0
HKD1_k127_3094829_15 Methyltransferase domain - - - 0.000000000000000000000524 105.0
HKD1_k127_3094829_16 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.00000002245 57.0
HKD1_k127_3094829_2 Uncharacterized membrane protein (DUF2298) - - - 1.525e-200 654.0
HKD1_k127_3094829_3 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 596.0
HKD1_k127_3094829_4 protein histidine kinase activity K02484,K07636,K07642 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 546.0
HKD1_k127_3094829_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 439.0
HKD1_k127_3094829_6 PFAM UbiA prenyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 351.0
HKD1_k127_3094829_7 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 314.0
HKD1_k127_3094829_8 TIGRFAM mevalonate kinase K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 296.0
HKD1_k127_3094829_9 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007448 275.0
HKD1_k127_31085_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1022.0
HKD1_k127_31085_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 570.0
HKD1_k127_31085_10 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 304.0
HKD1_k127_31085_11 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 300.0
HKD1_k127_31085_12 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 299.0
HKD1_k127_31085_13 COGs COG0395 ABC-type sugar transport system permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000106 285.0
HKD1_k127_31085_14 Family 4 glycosyl hydrolase K01222,K07406 - 3.2.1.22,3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002545 287.0
HKD1_k127_31085_15 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000004348 272.0
HKD1_k127_31085_16 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001127 257.0
HKD1_k127_31085_17 MFS_1 like family K08153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003893 261.0
HKD1_k127_31085_18 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000008287 232.0
HKD1_k127_31085_19 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000001487 221.0
HKD1_k127_31085_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 535.0
HKD1_k127_31085_20 Xylose isomerase-like TIM barrel K22233 - - 0.00000000000000000000000000000000000000000000000000000003256 206.0
HKD1_k127_31085_21 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.000000000000000000000000000000000000000000000000000005731 199.0
HKD1_k127_31085_22 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000001283 196.0
HKD1_k127_31085_23 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000006796 198.0
HKD1_k127_31085_24 Uncharacterized conserved protein (DUF2358) - - - 0.0000000000000000000000000000000000000000000000001226 181.0
HKD1_k127_31085_25 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.0000000000000000000000000000000000000000000000001551 187.0
HKD1_k127_31085_26 alcohol dehydrogenase K08322 - 1.1.1.380 0.000000000000000000000000000000000000000000000003608 186.0
HKD1_k127_31085_27 - - - - 0.0000000000000000000000000000000000000000000001566 194.0
HKD1_k127_31085_28 transcriptional regulator - - - 0.000000000000000000000000000000000000000000007521 175.0
HKD1_k127_31085_29 phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000596 166.0
HKD1_k127_31085_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 373.0
HKD1_k127_31085_30 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000001221 166.0
HKD1_k127_31085_31 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 0.000000000000000000000000000000000000008398 153.0
HKD1_k127_31085_32 Peptidase family M28 - - - 0.0000000000000000000000000001684 129.0
HKD1_k127_31085_33 Diguanylate cyclase - - - 0.0000000000000000000000000008513 132.0
HKD1_k127_31085_34 Staygreen protein K22013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006787,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009536,GO:0009579,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010271,GO:0015994,GO:0015996,GO:0016020,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031976,GO:0031984,GO:0033013,GO:0033015,GO:0034357,GO:0034641,GO:0042440,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044270,GO:0044422,GO:0044424,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046149,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051187,GO:0051193,GO:0051195,GO:0055035,GO:0065007,GO:0071704,GO:0090056,GO:1901360,GO:1901361,GO:1901401,GO:1901402,GO:1901404,GO:1901405,GO:1901564,GO:1901565,GO:1901575,GO:1903647 4.99.1.10 0.00000000000000000000008836 101.0
HKD1_k127_31085_35 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 0.0000000000000000002374 94.0
HKD1_k127_31085_36 PFAM Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000003526 84.0
HKD1_k127_31085_37 methyltransferase - - - 0.00000000000002245 80.0
HKD1_k127_31085_38 PFAM Archaeal ATPase - - - 0.0000000000004591 81.0
HKD1_k127_31085_39 - - - - 0.000000000002998 76.0
HKD1_k127_31085_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 358.0
HKD1_k127_31085_40 Cupin 2, conserved barrel domain protein - - - 0.00000004357 61.0
HKD1_k127_31085_41 SCP-2 sterol transfer family - - - 0.00000005765 59.0
HKD1_k127_31085_42 Transcriptional regulatory protein, C terminal - - - 0.0000000624 65.0
HKD1_k127_31085_43 PFAM ATP-binding region - - - 0.0000009851 63.0
HKD1_k127_31085_44 - - - - 0.000008779 54.0
HKD1_k127_31085_45 ATPase, AAA superfamily K06921 - - 0.000227 53.0
HKD1_k127_31085_5 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 357.0
HKD1_k127_31085_6 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 346.0
HKD1_k127_31085_7 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 334.0
HKD1_k127_31085_8 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 321.0
HKD1_k127_31085_9 PFAM Glycosyl transferase family 2 K14597 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 308.0
HKD1_k127_3124250_0 PFAM regulator of chromosome condensation, RCC1 - - - 2.891e-239 762.0
HKD1_k127_3124250_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 5.804e-195 625.0
HKD1_k127_3124250_10 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000007278 152.0
HKD1_k127_3124250_11 Protein of unknown function (DUF1706) - - - 0.0000000000000000000000000000000000125 141.0
HKD1_k127_3124250_12 dihydroorotate dehydrogenase activity K17828 - 1.3.1.14 0.00000000000000000000000000000000002647 144.0
HKD1_k127_3124250_13 - - - - 0.00000000000000000000000000000001516 128.0
HKD1_k127_3124250_14 2 iron, 2 sulfur cluster binding K02823,K05368 - 1.16.1.3,1.5.1.41 0.00000000000000000000000000000008234 133.0
HKD1_k127_3124250_15 beta-lactamase domain protein K05555 - - 0.00000000000000000000000000000009859 135.0
HKD1_k127_3124250_16 YbaB/EbfC DNA-binding family K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.000000000000000000000000000343 119.0
HKD1_k127_3124250_17 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000002552 115.0
HKD1_k127_3124250_18 - - - - 0.0000000000000000004187 88.0
HKD1_k127_3124250_19 - - - - 0.00000000000007507 72.0
HKD1_k127_3124250_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 544.0
HKD1_k127_3124250_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 496.0
HKD1_k127_3124250_4 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 477.0
HKD1_k127_3124250_5 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 402.0
HKD1_k127_3124250_6 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 361.0
HKD1_k127_3124250_7 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 302.0
HKD1_k127_3124250_8 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 285.0
HKD1_k127_3124250_9 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005193 273.0
HKD1_k127_3145027_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.228e-284 895.0
HKD1_k127_3145027_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 7.058e-233 735.0
HKD1_k127_3145027_10 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 347.0
HKD1_k127_3145027_11 TIGRFAM metal dependent phophohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 306.0
HKD1_k127_3145027_12 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075,K15780 - 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 304.0
HKD1_k127_3145027_13 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 293.0
HKD1_k127_3145027_14 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001089 286.0
HKD1_k127_3145027_15 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007355 273.0
HKD1_k127_3145027_16 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005374 254.0
HKD1_k127_3145027_17 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000226 247.0
HKD1_k127_3145027_18 PFAM peptidase, membrane zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000002217 224.0
HKD1_k127_3145027_19 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000006206 213.0
HKD1_k127_3145027_2 PFAM Amidohydrolase 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 576.0
HKD1_k127_3145027_20 Protein of unknown function (DUF692) - - - 0.000000000000000000000000000000000000000000000000000000000406 211.0
HKD1_k127_3145027_21 Coenzyme A transferase K01028,K01039 - 2.8.3.12,2.8.3.5 0.0000000000000000000000000000000000000000000000002384 186.0
HKD1_k127_3145027_22 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.00000000000000000000000000000000000000000000002102 178.0
HKD1_k127_3145027_23 Baseplate J-like protein K01218 - 3.2.1.78 0.000000000000000000000000000000000000000004396 166.0
HKD1_k127_3145027_24 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000002539 155.0
HKD1_k127_3145027_25 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000000000000002963 150.0
HKD1_k127_3145027_26 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000003619 158.0
HKD1_k127_3145027_27 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000151 113.0
HKD1_k127_3145027_28 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000003841 94.0
HKD1_k127_3145027_29 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000009325 89.0
HKD1_k127_3145027_3 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 452.0
HKD1_k127_3145027_30 Sortase family K07284 - 3.4.22.70 0.0000000003372 68.0
HKD1_k127_3145027_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 424.0
HKD1_k127_3145027_5 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 389.0
HKD1_k127_3145027_6 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 379.0
HKD1_k127_3145027_7 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 359.0
HKD1_k127_3145027_8 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 362.0
HKD1_k127_3145027_9 PFAM AAA-4 family protein K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 356.0
HKD1_k127_3149509_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.071e-273 850.0
HKD1_k127_3149509_1 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 1.775e-261 814.0
HKD1_k127_3149509_10 DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 520.0
HKD1_k127_3149509_12 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 479.0
HKD1_k127_3149509_13 PFAM aminotransferase class V K04127 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 430.0
HKD1_k127_3149509_14 PFAM ABC transporter related K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 419.0
HKD1_k127_3149509_15 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 410.0
HKD1_k127_3149509_16 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 380.0
HKD1_k127_3149509_17 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 366.0
HKD1_k127_3149509_18 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 356.0
HKD1_k127_3149509_19 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 357.0
HKD1_k127_3149509_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.326e-257 811.0
HKD1_k127_3149509_20 Cell division protein FtsA K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 344.0
HKD1_k127_3149509_21 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 334.0
HKD1_k127_3149509_22 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 317.0
HKD1_k127_3149509_23 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 319.0
HKD1_k127_3149509_24 NAD-dependent epimerase dehydratase K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 312.0
HKD1_k127_3149509_25 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 307.0
HKD1_k127_3149509_26 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001388 250.0
HKD1_k127_3149509_27 PFAM regulatory protein, ArsR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002965 246.0
HKD1_k127_3149509_28 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000001294 239.0
HKD1_k127_3149509_29 lipid binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000005533 237.0
HKD1_k127_3149509_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.885e-248 772.0
HKD1_k127_3149509_30 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000000000000000000000000000000000000000000002368 216.0
HKD1_k127_3149509_31 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000002546 195.0
HKD1_k127_3149509_32 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000003374 191.0
HKD1_k127_3149509_33 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000008342 192.0
HKD1_k127_3149509_34 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000004064 189.0
HKD1_k127_3149509_35 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000009132 189.0
HKD1_k127_3149509_36 methyltransferase - - - 0.000000000000000000000000000000000000000000002201 174.0
HKD1_k127_3149509_37 GDP-mannose mannosyl hydrolase activity K01515,K03574,K13669,K19710 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.53,3.6.1.13,3.6.1.55 0.0000000000000000000000000000000000000002834 155.0
HKD1_k127_3149509_38 PFAM Rieske 2Fe-2S domain protein K00363,K05710 - 1.7.1.15 0.00000000000000000000000000000000009567 136.0
HKD1_k127_3149509_39 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000001884 135.0
HKD1_k127_3149509_4 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 2.475e-221 694.0
HKD1_k127_3149509_40 - - - - 0.000000000000000000000000000000002725 139.0
HKD1_k127_3149509_41 Pfam:DUF59 - - - 0.0000000000000000000000000000002145 126.0
HKD1_k127_3149509_44 - - - - 0.00000000000000000000002538 106.0
HKD1_k127_3149509_45 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.000000000000000000001483 104.0
HKD1_k127_3149509_46 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000649 94.0
HKD1_k127_3149509_47 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000002591 76.0
HKD1_k127_3149509_48 peptidase M42 family protein - - - 0.0000004949 53.0
HKD1_k127_3149509_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009923 599.0
HKD1_k127_3149509_6 TIGRFAM FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 569.0
HKD1_k127_3149509_7 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 554.0
HKD1_k127_3149509_8 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 547.0
HKD1_k127_3149509_9 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 529.0
HKD1_k127_3212924_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 3.117e-197 632.0
HKD1_k127_3212924_1 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 419.0
HKD1_k127_3212924_10 - - - - 0.000000000000000000000000000000000000000000004642 173.0
HKD1_k127_3212924_11 Haem-degrading - - - 0.000000000000000000000000002044 116.0
HKD1_k127_3212924_12 ThiS family K03636 - - 0.000000000000001437 79.0
HKD1_k127_3212924_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 374.0
HKD1_k127_3212924_3 Two component transcriptional regulator, winged helix family K07669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 334.0
HKD1_k127_3212924_4 metallophosphoesterase K07096,K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001272 273.0
HKD1_k127_3212924_5 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001303 263.0
HKD1_k127_3212924_6 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000005272 212.0
HKD1_k127_3212924_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000009793 175.0
HKD1_k127_3212924_8 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000007454 173.0
HKD1_k127_3212924_9 - - - - 0.000000000000000000000000000000000000000000002421 171.0
HKD1_k127_3235744_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 298.0
HKD1_k127_3235744_1 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000001925 216.0
HKD1_k127_3235744_10 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0006343 43.0
HKD1_k127_3235744_2 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000003289 206.0
HKD1_k127_3235744_3 Histidine kinase K07777 - 2.7.13.3 0.000000000000000000000000000000000000000000001145 182.0
HKD1_k127_3235744_4 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000002729 158.0
HKD1_k127_3235744_5 B3 4 domain - - - 0.000000000000000000000000000000000000001863 156.0
HKD1_k127_3235744_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000004078 108.0
HKD1_k127_3235744_7 YHS domain - - - 0.000000000000000003419 85.0
HKD1_k127_3235744_8 SdpI/YhfL protein family - - - 0.00000000002756 68.0
HKD1_k127_3235744_9 Protein of unknown function (DUF1706) - - - 0.000004552 54.0
HKD1_k127_3261627_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 594.0
HKD1_k127_3261627_1 SMART Nucleotide binding protein, PINc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 456.0
HKD1_k127_3261627_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 293.0
HKD1_k127_3261627_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000002414 75.0
HKD1_k127_3261627_4 - - - - 0.000006437 49.0
HKD1_k127_3278158_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1149.0
HKD1_k127_3278158_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1084.0
HKD1_k127_3278158_10 PFAM Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 482.0
HKD1_k127_3278158_11 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 460.0
HKD1_k127_3278158_12 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 423.0
HKD1_k127_3278158_13 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 423.0
HKD1_k127_3278158_14 PFAM Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 404.0
HKD1_k127_3278158_15 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 331.0
HKD1_k127_3278158_16 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 316.0
HKD1_k127_3278158_17 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 295.0
HKD1_k127_3278158_18 UTRA K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002198 269.0
HKD1_k127_3278158_19 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000004556 218.0
HKD1_k127_3278158_2 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 7.45e-247 776.0
HKD1_k127_3278158_21 - - - - 0.00000000000000000000000000000000000000000000000001867 192.0
HKD1_k127_3278158_23 Receptor family ligand binding region K01999 - - 0.000000000000000000000002069 107.0
HKD1_k127_3278158_3 Pyridoxal-phosphate dependent enzyme - - - 3.121e-244 761.0
HKD1_k127_3278158_4 Amidohydrolase family - - - 8.103e-222 695.0
HKD1_k127_3278158_5 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 588.0
HKD1_k127_3278158_6 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 561.0
HKD1_k127_3278158_7 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 526.0
HKD1_k127_3278158_8 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 493.0
HKD1_k127_3278158_9 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 494.0
HKD1_k127_3286759_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 355.0
HKD1_k127_3286759_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 316.0
HKD1_k127_3286759_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 314.0
HKD1_k127_3286759_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001982 278.0
HKD1_k127_3286759_4 Sigma-70 region 2 K03088 - - 0.00000000000000000000764 99.0
HKD1_k127_3286759_5 spermidine synthase activity - - - 0.0000007448 53.0
HKD1_k127_3286759_6 organic phosphonate transport K02044 - - 0.0006659 52.0
HKD1_k127_3319946_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 5.776e-272 856.0
HKD1_k127_3319946_1 PFAM ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 473.0
HKD1_k127_3319946_2 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 403.0
HKD1_k127_3319946_3 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 339.0
HKD1_k127_3446004_0 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 367.0
HKD1_k127_3446004_1 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009025 284.0
HKD1_k127_3446004_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000006579 258.0
HKD1_k127_3456499_0 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 516.0
HKD1_k127_3456499_1 PFAM WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000001636 237.0
HKD1_k127_3456499_2 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000144 150.0
HKD1_k127_3456499_3 Domain of unknown function (DUF333) K14475 - - 0.0000000000000004737 88.0
HKD1_k127_3456499_4 - - - - 0.000000000000002022 79.0
HKD1_k127_3456499_5 metal-dependent membrane protease K07052 - - 0.0000000002162 71.0
HKD1_k127_3456499_6 - - - - 0.0000000333 59.0
HKD1_k127_3456499_7 - - - - 0.000001106 60.0
HKD1_k127_3456499_8 Permeases of the major facilitator superfamily - - - 0.00001818 54.0
HKD1_k127_3466834_0 Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.0 1215.0
HKD1_k127_3466834_1 PFAM NHL repeat containing protein - - - 0.0 1141.0
HKD1_k127_3466834_10 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 619.0
HKD1_k127_3466834_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 577.0
HKD1_k127_3466834_12 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 555.0
HKD1_k127_3466834_13 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 541.0
HKD1_k127_3466834_14 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 505.0
HKD1_k127_3466834_15 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 488.0
HKD1_k127_3466834_16 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00113 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 491.0
HKD1_k127_3466834_17 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 485.0
HKD1_k127_3466834_18 SMART AAA ATPase K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 478.0
HKD1_k127_3466834_19 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 482.0
HKD1_k127_3466834_2 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.0 1100.0
HKD1_k127_3466834_20 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 453.0
HKD1_k127_3466834_21 Belongs to the ABC transporter superfamily K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 453.0
HKD1_k127_3466834_22 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 439.0
HKD1_k127_3466834_23 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 434.0
HKD1_k127_3466834_24 pathogenesis K21471,K21687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 434.0
HKD1_k127_3466834_25 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 424.0
HKD1_k127_3466834_26 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 410.0
HKD1_k127_3466834_27 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 402.0
HKD1_k127_3466834_28 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 392.0
HKD1_k127_3466834_29 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 384.0
HKD1_k127_3466834_3 Domain of unknown function (DUF1998) K06877,K07451 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 2.764e-241 772.0
HKD1_k127_3466834_30 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 375.0
HKD1_k127_3466834_31 Domain of unknown function (DUF4032) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 373.0
HKD1_k127_3466834_32 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 364.0
HKD1_k127_3466834_33 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 361.0
HKD1_k127_3466834_34 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
HKD1_k127_3466834_35 family 4 K01222 - 3.2.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 354.0
HKD1_k127_3466834_36 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 341.0
HKD1_k127_3466834_37 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 327.0
HKD1_k127_3466834_38 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 318.0
HKD1_k127_3466834_39 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 313.0
HKD1_k127_3466834_4 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 8.039e-236 737.0
HKD1_k127_3466834_40 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 302.0
HKD1_k127_3466834_41 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 292.0
HKD1_k127_3466834_42 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001477 284.0
HKD1_k127_3466834_43 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00112 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002085 304.0
HKD1_k127_3466834_44 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002633 278.0
HKD1_k127_3466834_45 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01190 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000001105 271.0
HKD1_k127_3466834_46 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003462 263.0
HKD1_k127_3466834_47 nitrogen compound transport K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000000000000000002519 257.0
HKD1_k127_3466834_48 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000007794 241.0
HKD1_k127_3466834_49 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000008324 246.0
HKD1_k127_3466834_5 PFAM peptidase M20 - - - 1.271e-225 705.0
HKD1_k127_3466834_50 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007562 228.0
HKD1_k127_3466834_51 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000009451 226.0
HKD1_k127_3466834_52 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000002657 215.0
HKD1_k127_3466834_53 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000005687 215.0
HKD1_k127_3466834_54 PFAM membrane-flanked domain - - - 0.00000000000000000000000000000000000000000000000000001937 195.0
HKD1_k127_3466834_55 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000006125 190.0
HKD1_k127_3466834_56 GtrA-like protein - - - 0.000000000000000000000000000000000000000000000133 172.0
HKD1_k127_3466834_57 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000005897 167.0
HKD1_k127_3466834_58 Haem-binding domain - - - 0.00000000000000000000000000000000000000000002177 165.0
HKD1_k127_3466834_59 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000009893 159.0
HKD1_k127_3466834_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 8.042e-221 692.0
HKD1_k127_3466834_60 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000000000000000006255 135.0
HKD1_k127_3466834_61 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000004406 132.0
HKD1_k127_3466834_62 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000001173 130.0
HKD1_k127_3466834_63 Creatinine amidohydrolase - - - 0.000000000000000000000000000004405 134.0
HKD1_k127_3466834_64 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000005335 106.0
HKD1_k127_3466834_65 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000003301 98.0
HKD1_k127_3466834_66 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000001151 102.0
HKD1_k127_3466834_67 PFAM Cupin 2, conserved barrel - - - 0.000000000000000000004727 96.0
HKD1_k127_3466834_68 peptidyl-tyrosine sulfation - - - 0.0000000000000001359 84.0
HKD1_k127_3466834_69 PFAM UspA domain protein - - - 0.000000000000002084 86.0
HKD1_k127_3466834_7 beta-N-acetylhexosaminidase activity - - - 2.846e-205 655.0
HKD1_k127_3466834_70 PFAM ferredoxin - - - 0.00000000000003782 73.0
HKD1_k127_3466834_8 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 628.0
HKD1_k127_3466834_9 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 601.0
HKD1_k127_3503752_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 6.275e-307 954.0
HKD1_k127_3503752_1 Histidine kinase K07646 - 2.7.13.3 1.086e-296 934.0
HKD1_k127_3503752_10 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000003252 254.0
HKD1_k127_3503752_11 PFAM Diacylglycerol kinase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000707 236.0
HKD1_k127_3503752_12 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000002587 184.0
HKD1_k127_3503752_13 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000001834 171.0
HKD1_k127_3503752_14 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000007853 170.0
HKD1_k127_3503752_15 COG2076 Membrane transporters of cations and cationic drugs K03297,K11814 - - 0.000000000000000000000000000000009115 130.0
HKD1_k127_3503752_16 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000002842 113.0
HKD1_k127_3503752_17 O-methyltransferase activity K00543,K13169 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008172,GO:0008757,GO:0009058,GO:0009059,GO:0009308,GO:0009309,GO:0009987,GO:0010467,GO:0010817,GO:0016740,GO:0016741,GO:0017096,GO:0017144,GO:0018130,GO:0019438,GO:0019538,GO:0030186,GO:0030187,GO:0032259,GO:0034641,GO:0034645,GO:0034754,GO:0042401,GO:0042430,GO:0042435,GO:0042445,GO:0042446,GO:0042802,GO:0042803,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046483,GO:0046983,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1905939,GO:1905940,GO:2000018,GO:2000019,GO:2000026,GO:2000241,GO:2000242 2.1.1.4 0.000000000000000000000002568 114.0
HKD1_k127_3503752_18 Domain of unknown function (DUF4118) - - - 0.000000000003206 76.0
HKD1_k127_3503752_19 Cytochrome c - - - 0.00000000001201 69.0
HKD1_k127_3503752_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.62e-266 832.0
HKD1_k127_3503752_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 3.284e-257 805.0
HKD1_k127_3503752_4 CoA binding domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009491 591.0
HKD1_k127_3503752_5 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 457.0
HKD1_k127_3503752_6 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 376.0
HKD1_k127_3503752_7 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 327.0
HKD1_k127_3503752_8 PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 316.0
HKD1_k127_3503752_9 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000612 285.0
HKD1_k127_3613752_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 428.0
HKD1_k127_3613752_1 - - - - 0.00000000001785 68.0
HKD1_k127_3613752_2 cellulose binding - - - 0.000002986 50.0
HKD1_k127_3654784_0 Inner membrane component of T3SS, cytoplasmic domain - - - 3.924e-201 666.0
HKD1_k127_3654784_1 BPG-independent PGAM N-terminus (iPGM_N) K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 582.0
HKD1_k127_3654784_10 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 347.0
HKD1_k127_3654784_11 Phosphate transporter family protein K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 321.0
HKD1_k127_3654784_12 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 308.0
HKD1_k127_3654784_13 helix_turn _helix lactose operon repressor K05499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 300.0
HKD1_k127_3654784_14 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003456 271.0
HKD1_k127_3654784_15 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000654 246.0
HKD1_k127_3654784_16 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000001352 234.0
HKD1_k127_3654784_17 Branched-chain amino acid transport system / permease component K17214 - - 0.000000000000000000000000000000000000000000000000000000000000000002393 238.0
HKD1_k127_3654784_18 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000002085 249.0
HKD1_k127_3654784_19 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000002485 231.0
HKD1_k127_3654784_2 ABC transporter permease K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 517.0
HKD1_k127_3654784_20 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000002655 212.0
HKD1_k127_3654784_21 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.000000000000000000000000000000000000000000000004538 179.0
HKD1_k127_3654784_22 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000001691 184.0
HKD1_k127_3654784_23 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.000000000000000000000000000000000000000000007894 174.0
HKD1_k127_3654784_24 with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000007681 166.0
HKD1_k127_3654784_25 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.00000000000000000000000000000000000001097 162.0
HKD1_k127_3654784_26 Periplasmic substrate-binding component of the ATP-dependent ribose transport system K10439,K17202 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.0000000000000000000000000000000000003489 154.0
HKD1_k127_3654784_27 myo-inosose-2 dehydratase activity K01805 - 5.3.1.5 0.000000000000000000000000000000000000979 151.0
HKD1_k127_3654784_28 RpiR family transcriptional regulator - - - 0.00000000000000000000000000000003563 137.0
HKD1_k127_3654784_29 amidohydrolase K07045 - - 0.000000000000000000000000009293 120.0
HKD1_k127_3654784_3 tagaturonate epimerase K21619 - 5.1.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 498.0
HKD1_k127_3654784_30 Domain of unknown function (DUF2088) - - - 0.00000000000000000000004018 102.0
HKD1_k127_3654784_31 HAD-hyrolase-like K07025 - - 0.00000000000005778 85.0
HKD1_k127_3654784_32 uridine kinase K00855,K00867,K00876 - 2.7.1.19,2.7.1.33,2.7.1.48 0.00000000002282 76.0
HKD1_k127_3654784_33 Cupin 2, conserved barrel domain protein - - - 0.0000000002456 66.0
HKD1_k127_3654784_4 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 481.0
HKD1_k127_3654784_5 import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 481.0
HKD1_k127_3654784_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 454.0
HKD1_k127_3654784_7 creatininase K01470,K22232 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 451.0
HKD1_k127_3654784_8 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 448.0
HKD1_k127_3654784_9 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 365.0
HKD1_k127_3775304_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.017e-234 734.0
HKD1_k127_3775304_1 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 492.0
HKD1_k127_3775304_2 Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 426.0
HKD1_k127_3775304_3 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 405.0
HKD1_k127_3775304_4 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 389.0
HKD1_k127_3775304_5 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 369.0
HKD1_k127_3775304_6 maltose binding K02027,K15770 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 299.0
HKD1_k127_3775304_7 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000004334 231.0
HKD1_k127_3775304_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000009317 189.0
HKD1_k127_3775304_9 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000005286 172.0
HKD1_k127_392521_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.0 1347.0
HKD1_k127_392521_1 PFAM Aldehyde dehydrogenase K00128,K00131,K00135,K00140 - 1.2.1.16,1.2.1.18,1.2.1.20,1.2.1.27,1.2.1.3,1.2.1.79,1.2.1.9 4.207e-262 816.0
HKD1_k127_392521_10 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 332.0
HKD1_k127_392521_11 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 330.0
HKD1_k127_392521_12 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 315.0
HKD1_k127_392521_13 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001464 272.0
HKD1_k127_392521_14 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001642 256.0
HKD1_k127_392521_15 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002708 260.0
HKD1_k127_392521_16 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002852 252.0
HKD1_k127_392521_17 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000004803 231.0
HKD1_k127_392521_18 DinB family - - - 0.000000000000000000000000000000000000000000000003003 178.0
HKD1_k127_392521_19 - - - - 0.0000000000000000000000000000000000000000000004104 179.0
HKD1_k127_392521_2 Transcriptional activator domain - - - 7.676e-227 740.0
HKD1_k127_392521_20 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000838 156.0
HKD1_k127_392521_21 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000126 156.0
HKD1_k127_392521_22 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000006432 142.0
HKD1_k127_392521_23 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000001648 128.0
HKD1_k127_392521_24 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000001909 126.0
HKD1_k127_392521_25 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000003201 121.0
HKD1_k127_392521_26 PFAM zinc finger, SWIM domain protein - - - 0.00000000000000000000000002872 109.0
HKD1_k127_392521_27 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000008332 115.0
HKD1_k127_392521_28 heme a metabolic process K02259 - - 0.0000000000000000000000003826 116.0
HKD1_k127_392521_29 PFAM binding-protein-dependent transport systems inner membrane component K13890 - - 0.00000000000000000000000292 114.0
HKD1_k127_392521_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 5.069e-206 652.0
HKD1_k127_392521_30 - - - - 0.0000000000000000005752 87.0
HKD1_k127_392521_31 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000002842 82.0
HKD1_k127_392521_32 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000008836 79.0
HKD1_k127_392521_33 PFAM PQQ enzyme repeat K02014 - - 0.000000000000008538 89.0
HKD1_k127_392521_35 Phosphorylase superfamily K01243 - 3.2.2.9 0.000000000003055 76.0
HKD1_k127_392521_37 - - - - 0.000003752 49.0
HKD1_k127_392521_39 luxR family - - - 0.0002569 51.0
HKD1_k127_392521_4 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 536.0
HKD1_k127_392521_40 WD40-like Beta Propeller Repeat - - - 0.000404 53.0
HKD1_k127_392521_41 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0008386 48.0
HKD1_k127_392521_5 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 505.0
HKD1_k127_392521_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 496.0
HKD1_k127_392521_7 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 436.0
HKD1_k127_392521_8 Thioredoxin reductase K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 358.0
HKD1_k127_392521_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 353.0
HKD1_k127_3969030_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.75e-271 845.0
HKD1_k127_3969030_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 1.987e-234 747.0
HKD1_k127_3969030_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.072e-225 709.0
HKD1_k127_3969030_3 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009964 525.0
HKD1_k127_3969030_4 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 414.0
HKD1_k127_3969030_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 302.0
HKD1_k127_3969030_6 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 293.0
HKD1_k127_3969030_7 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000000007956 174.0
HKD1_k127_4008040_0 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 395.0
HKD1_k127_4008040_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 380.0
HKD1_k127_4008040_2 Lysin motif - - - 0.0000000000000000000000000000000000000000000000001186 188.0
HKD1_k127_4008040_3 Regulatory protein, FmdB family - - - 0.000000000000000000000000003337 112.0
HKD1_k127_4008040_4 S-layer homology domain - - - 0.00000000000000002282 96.0
HKD1_k127_4008040_5 Winged helix DNA-binding domain - - - 0.000000000003674 70.0
HKD1_k127_4039043_0 PFAM type II secretion system protein E K02283 - - 3.073e-233 728.0
HKD1_k127_4039043_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 4.575e-208 652.0
HKD1_k127_4039043_10 Flp pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001035 256.0
HKD1_k127_4039043_12 Pfam:DUF2029 - - - 0.0000000000000000000000000000000000000000000000000000000000006846 225.0
HKD1_k127_4039043_13 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000001082 219.0
HKD1_k127_4039043_14 Pfam:DUF2029 - - - 0.000000000000000000000000000000000000000000000000005228 196.0
HKD1_k127_4039043_16 PFAM type II secretion system protein K12511 - - 0.00000000000000000000000000000000000004858 148.0
HKD1_k127_4039043_17 PFAM Flp Fap pilin component K02651 - - 0.000000004699 59.0
HKD1_k127_4039043_2 PFAM FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 572.0
HKD1_k127_4039043_20 PFAM Prenyltransferase and squalene oxidase repeat K06045 - 4.2.1.129,5.4.99.17 0.0000009457 60.0
HKD1_k127_4039043_3 PFAM response regulator receiver K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 484.0
HKD1_k127_4039043_4 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 397.0
HKD1_k127_4039043_5 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 354.0
HKD1_k127_4039043_6 histidine kinase, dimerisation and phosphoacceptor region K07777 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 334.0
HKD1_k127_4039043_7 PFAM type II secretion system protein K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 330.0
HKD1_k127_4039043_8 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001035 290.0
HKD1_k127_4085768_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 364.0
HKD1_k127_4085768_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 337.0
HKD1_k127_4085768_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001587 282.0
HKD1_k127_4085768_3 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002182 290.0
HKD1_k127_4085768_4 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000008668 239.0
HKD1_k127_4085768_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000007058 220.0
HKD1_k127_4085768_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000002674 185.0
HKD1_k127_4085768_7 carbohydrate transport K02027,K10117,K17318 - - 0.00000000000000000000000000000000000000000000000006494 198.0
HKD1_k127_4085768_8 PFAM peptidase U32 K08303 - - 0.00000000000001394 76.0
HKD1_k127_4085768_9 - - - - 0.00000000006121 68.0
HKD1_k127_4107002_0 domain protein - - - 4.573e-196 666.0
HKD1_k127_4107002_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 331.0
HKD1_k127_4107002_10 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000399 170.0
HKD1_k127_4107002_11 Bleomycin resistance protein K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000004918 160.0
HKD1_k127_4107002_12 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000007387 140.0
HKD1_k127_4107002_13 Efflux transporter, RND family, MFP subunit - - - 0.00000999 59.0
HKD1_k127_4107002_14 Tetratricopeptide repeat - - - 0.00001024 57.0
HKD1_k127_4107002_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 324.0
HKD1_k127_4107002_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 287.0
HKD1_k127_4107002_4 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003097 306.0
HKD1_k127_4107002_5 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001719 257.0
HKD1_k127_4107002_6 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002464 264.0
HKD1_k127_4107002_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000031 206.0
HKD1_k127_4107002_8 Aminoacyl-tRNA editing domain K03976 - - 0.0000000000000000000000000000000000000000000000000128 184.0
HKD1_k127_4107002_9 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000771 185.0
HKD1_k127_4121136_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1382.0
HKD1_k127_4121136_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1016.0
HKD1_k127_4121136_10 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 385.0
HKD1_k127_4121136_11 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 384.0
HKD1_k127_4121136_12 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 343.0
HKD1_k127_4121136_13 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002716 288.0
HKD1_k127_4121136_14 glycosyl transferase group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000001636 278.0
HKD1_k127_4121136_15 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000546 268.0
HKD1_k127_4121136_16 Electron transfer flavoprotein alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008894 262.0
HKD1_k127_4121136_17 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000408 233.0
HKD1_k127_4121136_18 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000001264 222.0
HKD1_k127_4121136_19 KR domain K04708 - 1.1.1.102 0.000000000000000000000000000000000000000000000000000000000004446 218.0
HKD1_k127_4121136_2 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 1.373e-320 1005.0
HKD1_k127_4121136_20 electron transfer activity K03521 - - 0.00000000000000000000000000000000000000000000000000000000002158 214.0
HKD1_k127_4121136_21 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000394 205.0
HKD1_k127_4121136_22 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000001374 195.0
HKD1_k127_4121136_24 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000474 151.0
HKD1_k127_4121136_25 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000005567 140.0
HKD1_k127_4121136_26 spore germination K03605 - - 0.000000000000000000000000000695 119.0
HKD1_k127_4121136_27 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000001192 107.0
HKD1_k127_4121136_28 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000006082 101.0
HKD1_k127_4121136_29 proteolysis K21140 - 3.13.1.6 0.0000000000000000000001574 103.0
HKD1_k127_4121136_3 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.564e-254 802.0
HKD1_k127_4121136_30 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000002346 93.0
HKD1_k127_4121136_31 phosphorelay signal transduction system - - - 0.00000000000000001964 87.0
HKD1_k127_4121136_4 Nickel-dependent hydrogenase K14126 - 1.8.98.5 3.78e-227 714.0
HKD1_k127_4121136_5 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 5.441e-226 714.0
HKD1_k127_4121136_6 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 5.327e-221 704.0
HKD1_k127_4121136_7 Fe-S oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 524.0
HKD1_k127_4121136_8 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 409.0
HKD1_k127_4121136_9 Histidine kinase HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 420.0
HKD1_k127_4132877_0 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 397.0
HKD1_k127_4132877_1 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 291.0
HKD1_k127_4132877_2 ABC transporter K02006 - - 0.00000000000000000000000000000000000000000000000000004696 192.0
HKD1_k127_4132877_3 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000002156 123.0
HKD1_k127_4132877_4 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000005763 117.0
HKD1_k127_4132877_5 COGs COG3666 Transposase and inactivated derivatives K07487 - - 0.00000000000000000001223 93.0
HKD1_k127_4139521_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0 1162.0
HKD1_k127_4139521_1 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 608.0
HKD1_k127_4139521_10 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 353.0
HKD1_k127_4139521_11 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 330.0
HKD1_k127_4139521_12 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 315.0
HKD1_k127_4139521_13 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 308.0
HKD1_k127_4139521_14 PFAM RNA binding S1 domain protein K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 298.0
HKD1_k127_4139521_15 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000001977 158.0
HKD1_k127_4139521_16 acetyltransferase K06889,K19273 - - 0.00000000000000000000000000000000002257 141.0
HKD1_k127_4139521_17 - - - - 0.000000000000000000000000000000001243 138.0
HKD1_k127_4139521_18 ComEA protein K02237 - - 0.000000000000000000000000000000005045 135.0
HKD1_k127_4139521_19 PFAM CoA-binding domain protein K01905,K09181,K22224 - 6.2.1.13 0.00000000000002736 74.0
HKD1_k127_4139521_2 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 589.0
HKD1_k127_4139521_3 N-terminal 7TM region of histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 567.0
HKD1_k127_4139521_4 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 529.0
HKD1_k127_4139521_5 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 454.0
HKD1_k127_4139521_6 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 453.0
HKD1_k127_4139521_7 LysM domain K03046,K03641,K08642 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 451.0
HKD1_k127_4139521_8 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 409.0
HKD1_k127_4139521_9 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 370.0
HKD1_k127_4141409_0 Belongs to the RtcB family K14415 - 6.5.1.3 3.857e-238 743.0
HKD1_k127_4141409_1 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 465.0
HKD1_k127_4141409_10 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000006967 132.0
HKD1_k127_4141409_11 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000003591 125.0
HKD1_k127_4141409_12 Protein of unknown function with PCYCGC motif - - - 0.00000000000000000000002057 105.0
HKD1_k127_4141409_13 PFAM Forkhead-associated protein - - - 0.00000000000000000000003179 109.0
HKD1_k127_4141409_14 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000003194 96.0
HKD1_k127_4141409_15 - K02275,K17686 - 1.9.3.1,3.6.3.54 0.000000000000001862 87.0
HKD1_k127_4141409_17 Iron permease FTR1 family K07243 - - 0.0000009192 60.0
HKD1_k127_4141409_2 Glycosyltransferase Family 4 K21369 - 2.4.1.270 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 311.0
HKD1_k127_4141409_3 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004155 292.0
HKD1_k127_4141409_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000009828 222.0
HKD1_k127_4141409_5 - - - - 0.0000000000000000000000000000000000000000000007141 183.0
HKD1_k127_4141409_6 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000000000000000000000002158 169.0
HKD1_k127_4141409_7 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000005726 147.0
HKD1_k127_4141409_8 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.000000000000000000000000000000000000118 158.0
HKD1_k127_4141409_9 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000000000000000001347 157.0
HKD1_k127_4142435_0 PFAM ABC transporter related K01990,K16907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004838 275.0
HKD1_k127_4142435_1 tungstate ion transport K01990,K07705,K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000008794 231.0
HKD1_k127_4142435_2 transmembrane transport K01992 - - 0.000000000003157 80.0
HKD1_k127_4153253_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 9.637e-313 969.0
HKD1_k127_4153253_1 PFAM ABC transporter transmembrane region K06147 - - 9.661e-238 753.0
HKD1_k127_4153253_10 PFAM peptidase S58, DmpA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 414.0
HKD1_k127_4153253_11 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 363.0
HKD1_k127_4153253_12 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 362.0
HKD1_k127_4153253_13 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 352.0
HKD1_k127_4153253_14 PFAM ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 327.0
HKD1_k127_4153253_15 Glycosyl transferase, family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 316.0
HKD1_k127_4153253_16 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 284.0
HKD1_k127_4153253_17 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009379 284.0
HKD1_k127_4153253_18 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000002483 254.0
HKD1_k127_4153253_19 PFAM Glycosyl transferase family 2 K07011,K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000003885 235.0
HKD1_k127_4153253_2 Immune inhibitor A peptidase M6 - - - 9.682e-211 676.0
HKD1_k127_4153253_20 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000002773 225.0
HKD1_k127_4153253_21 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000001964 180.0
HKD1_k127_4153253_22 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000000000000001805 136.0
HKD1_k127_4153253_24 Methylated dna-protein cysteine methyltransferase K07443 - - 0.00000000000000000002763 95.0
HKD1_k127_4153253_26 gas vesicle protein - - - 0.000009081 50.0
HKD1_k127_4153253_27 extracellular matrix structural constituent - - - 0.00006442 54.0
HKD1_k127_4153253_3 Belongs to the thiolase family - - - 8.668e-204 640.0
HKD1_k127_4153253_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 557.0
HKD1_k127_4153253_5 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 507.0
HKD1_k127_4153253_6 Glycogen debranching enzyme, glucanotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 458.0
HKD1_k127_4153253_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 450.0
HKD1_k127_4153253_8 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 443.0
HKD1_k127_4153253_9 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 427.0
HKD1_k127_4168718_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 438.0
HKD1_k127_4168718_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 392.0
HKD1_k127_4168718_2 transferase activity, transferring glycosyl groups K21011,K21012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 299.0
HKD1_k127_4168718_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001177 259.0
HKD1_k127_4168718_4 serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000001488 157.0
HKD1_k127_4171495_0 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 503.0
HKD1_k127_4171495_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 375.0
HKD1_k127_4171495_2 Cytochrome b subunit of the bc K00412,K02635 - - 0.00000000000000000000000000000000000000000000000000000000000000000715 237.0
HKD1_k127_4171495_3 helix_turn_helix, Lux Regulon K02282 - - 0.000000000000000000000000000000000000001507 151.0
HKD1_k127_4171495_4 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.00000000000000000000000000354 124.0
HKD1_k127_4171495_5 Rieske [2Fe-2S] domain - - - 0.0000000000000000000005613 102.0
HKD1_k127_4171495_6 ubiquinol-cytochrome-c reductase activity K00412 GO:0000003,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0006091,GO:0006119,GO:0006122,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0007275,GO:0007276,GO:0007283,GO:0007584,GO:0008121,GO:0008150,GO:0008152,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009408,GO:0009605,GO:0009628,GO:0009636,GO:0009651,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0014070,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016679,GO:0016681,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0019953,GO:0020037,GO:0022414,GO:0022900,GO:0022904,GO:0031090,GO:0031099,GO:0031100,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031667,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032504,GO:0032592,GO:0032991,GO:0033273,GO:0033590,GO:0033762,GO:0034220,GO:0034641,GO:0036293,GO:0036296,GO:0042221,GO:0042493,GO:0042538,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043434,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044703,GO:0044877,GO:0045275,GO:0045333,GO:0045471,GO:0046034,GO:0046483,GO:0046677,GO:0046686,GO:0046688,GO:0046689,GO:0046906,GO:0048037,GO:0048038,GO:0048039,GO:0048232,GO:0048513,GO:0048609,GO:0048731,GO:0048856,GO:0050896,GO:0051179,GO:0051234,GO:0051592,GO:0051704,GO:0055085,GO:0055086,GO:0055093,GO:0055114,GO:0070069,GO:0070469,GO:0070482,GO:0071704,GO:0072521,GO:0097159,GO:0097305,GO:0098573,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1901652,GO:1901698,GO:1901700,GO:1902494,GO:1902600,GO:1990204 - 0.00000000000002193 78.0
HKD1_k127_4177227_0 PFAM ABC transporter related K16786,K16787 - - 6.336e-220 697.0
HKD1_k127_4177227_1 Cobalt transport protein K16785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 296.0
HKD1_k127_4177227_2 ECF-type riboflavin transporter, S component K16924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000142 277.0
HKD1_k127_4177227_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000006992 163.0
HKD1_k127_4180218_0 PFAM single-stranded nucleic acid binding R3H domain protein - - - 1.205e-228 719.0
HKD1_k127_4180218_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 529.0
HKD1_k127_4180218_10 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 317.0
HKD1_k127_4180218_11 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 318.0
HKD1_k127_4180218_12 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 325.0
HKD1_k127_4180218_13 heme binding K21472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 290.0
HKD1_k127_4180218_14 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001773 276.0
HKD1_k127_4180218_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007657 276.0
HKD1_k127_4180218_16 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001926 263.0
HKD1_k127_4180218_17 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000005039 246.0
HKD1_k127_4180218_18 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000005628 245.0
HKD1_k127_4180218_19 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000002595 228.0
HKD1_k127_4180218_2 PFAM Major Facilitator Superfamily K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 507.0
HKD1_k127_4180218_21 phosphorelay signal transduction system K07670 - - 0.000000000000000000000000000000000000000000000000000000000000008606 223.0
HKD1_k127_4180218_22 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000001647 225.0
HKD1_k127_4180218_23 His Kinase A (phosphoacceptor) domain K07641,K10819 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000005979 236.0
HKD1_k127_4180218_24 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.000000000000000000000000000000000000000000000000000001214 200.0
HKD1_k127_4180218_25 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000377 199.0
HKD1_k127_4180218_26 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000003816 196.0
HKD1_k127_4180218_27 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.0000000000000000000000000000000000000000000000000001871 199.0
HKD1_k127_4180218_28 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000003722 180.0
HKD1_k127_4180218_29 Putative regulatory protein - - - 0.0000000000000000000000000000000000000000000001603 171.0
HKD1_k127_4180218_3 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 508.0
HKD1_k127_4180218_30 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000000000000000000000002204 162.0
HKD1_k127_4180218_31 Domain of unknown function (DUF1905) - - - 0.00000000000000000000000000000000000000000317 160.0
HKD1_k127_4180218_32 TIGRFAM addiction module toxin, Txe YoeB family K19158 - - 0.000000000000000000000000000000000000002075 148.0
HKD1_k127_4180218_33 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000006478 154.0
HKD1_k127_4180218_34 - - - - 0.0000000000000000000000000000000003945 137.0
HKD1_k127_4180218_36 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000009637 125.0
HKD1_k127_4180218_38 Antitoxin component of a toxin-antitoxin (TA) module K19159 - - 0.00000000000000000000000002172 111.0
HKD1_k127_4180218_39 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000006375 113.0
HKD1_k127_4180218_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 479.0
HKD1_k127_4180218_40 Alkylmercury lyase - - - 0.000000000000000000003779 95.0
HKD1_k127_4180218_41 Transcriptional K07979 - - 0.00000000000000000001934 95.0
HKD1_k127_4180218_42 Belongs to the ParB family K03497 - - 0.00000000000001585 85.0
HKD1_k127_4180218_44 Alkylmercury lyase - - - 0.000000000405 62.0
HKD1_k127_4180218_45 - - - - 0.00000006016 57.0
HKD1_k127_4180218_46 Ethyl tert-butyl ether degradation - - - 0.000004138 55.0
HKD1_k127_4180218_47 - - - - 0.0000139 52.0
HKD1_k127_4180218_48 - - - - 0.0001615 53.0
HKD1_k127_4180218_5 DNA methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 430.0
HKD1_k127_4180218_6 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 424.0
HKD1_k127_4180218_7 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 383.0
HKD1_k127_4180218_8 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009789 370.0
HKD1_k127_4180218_9 Formate/nitrite transporter K06212 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 354.0
HKD1_k127_4186138_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 3.08e-301 934.0
HKD1_k127_4186138_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 578.0
HKD1_k127_4186138_10 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002451 265.0
HKD1_k127_4186138_11 SMART helix-turn-helix domain protein K15539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001141 273.0
HKD1_k127_4186138_12 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000005756 254.0
HKD1_k127_4186138_13 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002163 253.0
HKD1_k127_4186138_14 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002547 258.0
HKD1_k127_4186138_15 Responsible for synthesis of pseudouridine from uracil K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000001032 208.0
HKD1_k127_4186138_16 Aminoacyl-tRNA editing domain K01284 - 3.4.15.5 0.000000000000000000000000000000000000000000000000000000137 199.0
HKD1_k127_4186138_17 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003783 192.0
HKD1_k127_4186138_18 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000005626 160.0
HKD1_k127_4186138_19 PFAM Rieske 2Fe-2S domain K03886 - - 0.00000000000000000000000000009347 121.0
HKD1_k127_4186138_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 501.0
HKD1_k127_4186138_20 xanthine phosphoribosyltransferase activity K00769,K07101 - 2.4.2.22 0.0000000000000000000000004039 109.0
HKD1_k127_4186138_21 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.000000000000000000000001554 117.0
HKD1_k127_4186138_22 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000002049 64.0
HKD1_k127_4186138_23 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000001842 56.0
HKD1_k127_4186138_24 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000003951 54.0
HKD1_k127_4186138_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 426.0
HKD1_k127_4186138_4 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 407.0
HKD1_k127_4186138_5 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 375.0
HKD1_k127_4186138_6 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 326.0
HKD1_k127_4186138_7 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 316.0
HKD1_k127_4186138_8 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004145 283.0
HKD1_k127_4186138_9 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002126 285.0
HKD1_k127_4203722_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 1.78e-266 829.0
HKD1_k127_4203722_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000001905 162.0
HKD1_k127_4203722_2 Radical SAM - - - 0.00000000000000000000000000000000231 138.0
HKD1_k127_4214205_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1193.0
HKD1_k127_4214205_1 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 462.0
HKD1_k127_4214205_2 Metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002123 285.0
HKD1_k127_4214205_3 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006966 307.0
HKD1_k127_4214205_4 C-terminal domain of CHU protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000008794 244.0
HKD1_k127_4214205_5 PFAM glycoside hydrolase family 9 K01179 - 3.2.1.4 0.00000001502 68.0
HKD1_k127_4214205_7 PFAM SMP-30 Gluconolaconase - - - 0.0009561 52.0
HKD1_k127_4222130_0 Streptomycin adenylyltransferase K05593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 333.0
HKD1_k127_4222130_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 314.0
HKD1_k127_4222130_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003635 245.0
HKD1_k127_4222130_3 Streptomycin adenylyltransferase K05593 - - 0.000000000000000000000000000000000000000000000000000009933 200.0
HKD1_k127_4222130_4 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000008142 185.0
HKD1_k127_4222130_5 - - - - 0.00000000000000000000000000000000000000000000001536 174.0
HKD1_k127_4222130_6 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000003407 165.0
HKD1_k127_4222130_7 CAAX protease self-immunity - - - 0.00000000000000000000000000004375 124.0
HKD1_k127_4222130_8 Protein of unknown function (DUF1572) - - - 0.0000000000000000005079 93.0
HKD1_k127_4222130_9 - - - - 0.00003679 52.0
HKD1_k127_4231680_0 - - - - 0.000000000000000000000000000000000000000000000000000000000001325 217.0
HKD1_k127_4231680_1 PFAM regulatory protein, MerR - - - 0.000000000000000000000000000142 123.0
HKD1_k127_4231680_2 PFAM phospholipase D Transphosphatidylase - - - 0.0000000000000000000001355 104.0
HKD1_k127_4231680_3 - - - - 0.0000000000000000000003688 104.0
HKD1_k127_4241241_0 (ABC) transporter K06147,K11085 - - 3.285e-246 773.0
HKD1_k127_4241241_1 - K07138 - - 5.28e-199 625.0
HKD1_k127_4241241_10 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000001231 219.0
HKD1_k127_4241241_11 PFAM secretion protein HlyD family protein K01993 - - 0.000000000000000000000000000000000000000000000000002004 199.0
HKD1_k127_4241241_12 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000007841 189.0
HKD1_k127_4241241_13 PFAM Appr-1-p processing domain protein - - - 0.000000000000000000000000000000000000000000001041 171.0
HKD1_k127_4241241_14 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000003917 166.0
HKD1_k127_4241241_15 Protein of unknown function (DUF2089) - - - 0.000000000000000000000000000000000000003109 149.0
HKD1_k127_4241241_16 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000003855 148.0
HKD1_k127_4241241_17 - - - - 0.0000000000000000000000000000000000107 151.0
HKD1_k127_4241241_18 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000005889 111.0
HKD1_k127_4241241_19 - - - - 0.000000000000000000000001173 107.0
HKD1_k127_4241241_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008561 521.0
HKD1_k127_4241241_21 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000002364 94.0
HKD1_k127_4241241_22 Putative adhesin - - - 0.00000000001829 75.0
HKD1_k127_4241241_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 420.0
HKD1_k127_4241241_4 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 369.0
HKD1_k127_4241241_5 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 355.0
HKD1_k127_4241241_6 Fumarase C-terminus K01676,K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 309.0
HKD1_k127_4241241_7 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 290.0
HKD1_k127_4241241_8 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000436 257.0
HKD1_k127_4241241_9 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006056 249.0
HKD1_k127_4268955_0 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 362.0
HKD1_k127_4268955_1 overlaps another CDS with the same product name K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000082 277.0
HKD1_k127_4268955_2 PFAM ABC-2 type transporter K01992,K09690 - - 0.0000000000000000000000000000000000000000000000000002805 194.0
HKD1_k127_4268955_3 mitochondrial respiratory chain complex IV assembly K14998 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.00000000000000000000000000000000000000005267 161.0
HKD1_k127_4268955_5 SCO1/SenC K03619,K07152 GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 - 0.0000000000002668 72.0
HKD1_k127_4295153_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 3.696e-321 1005.0
HKD1_k127_4295153_1 metal-dependent phosphohydrolase, HD sub domain K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 616.0
HKD1_k127_4295153_10 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 324.0
HKD1_k127_4295153_11 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002352 259.0
HKD1_k127_4295153_12 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000003566 254.0
HKD1_k127_4295153_13 MoeA C-terminal region (domain IV) K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000007025 217.0
HKD1_k127_4295153_14 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000001176 208.0
HKD1_k127_4295153_16 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000005763 166.0
HKD1_k127_4295153_17 PFAM diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000000000001178 152.0
HKD1_k127_4295153_18 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000002179 151.0
HKD1_k127_4295153_19 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000006968 123.0
HKD1_k127_4295153_2 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 515.0
HKD1_k127_4295153_21 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000008393 117.0
HKD1_k127_4295153_22 23S rRNA-intervening sequence protein - - - 0.0000000000000000000001784 102.0
HKD1_k127_4295153_23 regulatory protein LysR K02019 - - 0.000000000000000000001286 95.0
HKD1_k127_4295153_3 modification enzyme, MiaB family K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 453.0
HKD1_k127_4295153_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 445.0
HKD1_k127_4295153_5 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 434.0
HKD1_k127_4295153_6 deoxyribonuclease IV (phage-T4-induced) activity K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 361.0
HKD1_k127_4295153_7 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 342.0
HKD1_k127_4295153_8 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 341.0
HKD1_k127_4295153_9 ABC transporter K02017,K06857 - 3.6.3.29,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 329.0
HKD1_k127_4302689_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 346.0
HKD1_k127_4302689_1 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000006874 192.0
HKD1_k127_4302689_2 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000005355 183.0
HKD1_k127_4302689_3 PFAM Endonuclease exonuclease phosphatase - - - 0.00000006269 65.0
HKD1_k127_4381960_0 Peptidase S9 prolyl oligopeptidase active site domain protein K01303 - 3.4.19.1 3.933e-197 632.0
HKD1_k127_4381960_1 PFAM SMC domain protein K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 589.0
HKD1_k127_4381960_10 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 353.0
HKD1_k127_4381960_11 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 347.0
HKD1_k127_4381960_12 saccharopine dehydrogenase activity K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 344.0
HKD1_k127_4381960_13 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 302.0
HKD1_k127_4381960_14 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 299.0
HKD1_k127_4381960_15 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 285.0
HKD1_k127_4381960_16 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007935 284.0
HKD1_k127_4381960_17 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000001425 229.0
HKD1_k127_4381960_18 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000126 225.0
HKD1_k127_4381960_19 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000007955 226.0
HKD1_k127_4381960_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 531.0
HKD1_k127_4381960_20 AAA domain - - - 0.0000000000000000000000000000000000000000000000000013 186.0
HKD1_k127_4381960_21 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.0000000000000000000000000000000000000000000000006476 179.0
HKD1_k127_4381960_22 TIGRFAM phosphodiesterase, MJ0936 family K07095 - - 0.000000000000000000000000000000000000000001327 162.0
HKD1_k127_4381960_23 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000325 153.0
HKD1_k127_4381960_24 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000002793 141.0
HKD1_k127_4381960_25 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000407 81.0
HKD1_k127_4381960_26 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.0000001733 59.0
HKD1_k127_4381960_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 507.0
HKD1_k127_4381960_4 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 494.0
HKD1_k127_4381960_5 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 441.0
HKD1_k127_4381960_6 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 429.0
HKD1_k127_4381960_7 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 394.0
HKD1_k127_4381960_8 Thg1 C terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 382.0
HKD1_k127_4381960_9 PFAM Shikimate quinate 5-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 356.0
HKD1_k127_4388910_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 1.704e-265 833.0
HKD1_k127_4388910_1 PFAM Glycoside hydrolase family 42 domain protein K12308 - 3.2.1.23 1.496e-252 796.0
HKD1_k127_4388910_10 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 340.0
HKD1_k127_4388910_12 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 321.0
HKD1_k127_4388910_13 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 333.0
HKD1_k127_4388910_14 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 320.0
HKD1_k127_4388910_15 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 300.0
HKD1_k127_4388910_16 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007137 279.0
HKD1_k127_4388910_17 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000111 277.0
HKD1_k127_4388910_18 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003024 255.0
HKD1_k127_4388910_19 PFAM binding-protein-dependent transport systems inner membrane component K02026,K10190,K10242 - - 0.0000000000000000000000000000000000000000000000000000000000000001016 231.0
HKD1_k127_4388910_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.146e-236 743.0
HKD1_k127_4388910_20 helix_turn_helix, Lux Regulon K14979 - - 0.000000000000000000000000000000000000000000000000000000000000009809 222.0
HKD1_k127_4388910_21 Binding-protein-dependent transport system inner membrane component K10189,K10241,K17235 - - 0.00000000000000000000000000000000000000000000000000000000000003144 226.0
HKD1_k127_4388910_22 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000001523 218.0
HKD1_k127_4388910_23 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000001024 194.0
HKD1_k127_4388910_24 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000003068 182.0
HKD1_k127_4388910_25 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000000000000000000000003683 175.0
HKD1_k127_4388910_27 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000001247 124.0
HKD1_k127_4388910_28 Parallel beta-helix repeat-containing protein - - - 0.0000000000000000000000000192 124.0
HKD1_k127_4388910_29 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000418 115.0
HKD1_k127_4388910_3 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 530.0
HKD1_k127_4388910_30 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000387 107.0
HKD1_k127_4388910_31 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000009449 96.0
HKD1_k127_4388910_32 - - - - 0.0000000008905 65.0
HKD1_k127_4388910_33 exo-alpha-(2->6)-sialidase activity K02388,K02396 - - 0.0009394 52.0
HKD1_k127_4388910_4 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 528.0
HKD1_k127_4388910_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 409.0
HKD1_k127_4388910_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 407.0
HKD1_k127_4388910_7 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 417.0
HKD1_k127_4388910_8 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 402.0
HKD1_k127_4388910_9 Psort location CytoplasmicMembrane, score 9.49 K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 374.0
HKD1_k127_4451832_0 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004683 280.0
HKD1_k127_4451832_1 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002363 257.0
HKD1_k127_447908_0 Two component transcriptional regulator, winged helix family K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 294.0
HKD1_k127_447908_1 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003774 267.0
HKD1_k127_447908_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000001849 175.0
HKD1_k127_447908_3 nitric oxide dioxygenase activity K17247 - - 0.000000000000000000000000007412 121.0
HKD1_k127_4511461_0 PFAM ABC transporter related K02056 - 3.6.3.17 2.776e-216 682.0
HKD1_k127_4511461_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 544.0
HKD1_k127_4511461_10 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000000000000000000001462 178.0
HKD1_k127_4511461_11 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000001708 150.0
HKD1_k127_4511461_12 phosphorelay signal transduction system - - - 0.000000000000000000000000004005 124.0
HKD1_k127_4511461_13 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000003996 103.0
HKD1_k127_4511461_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 541.0
HKD1_k127_4511461_3 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 535.0
HKD1_k127_4511461_4 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 508.0
HKD1_k127_4511461_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 397.0
HKD1_k127_4511461_6 PFAM basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 324.0
HKD1_k127_4511461_7 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 329.0
HKD1_k127_4511461_8 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006204 276.0
HKD1_k127_4511461_9 CBS domain containing protein K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001504 280.0
HKD1_k127_4534538_0 PFAM metal-dependent phosphohydrolase HD sub domain K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 286.0
HKD1_k127_4534538_1 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002237 255.0
HKD1_k127_4534538_2 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.0000000000000000000000000000000000000000000000000000000009257 204.0
HKD1_k127_4534538_3 Domain of unknown function (DUF333) K14475 - - 0.0000000000008865 76.0
HKD1_k127_4553208_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1050.0
HKD1_k127_4553208_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000001725 224.0
HKD1_k127_4553208_10 - - - - 0.000334 50.0
HKD1_k127_4553208_2 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000000000000000000000007735 171.0
HKD1_k127_4553208_3 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000000004001 134.0
HKD1_k127_4553208_4 - - - - 0.0000000000000001445 87.0
HKD1_k127_4553208_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000004801 72.0
HKD1_k127_4553208_6 Cytochrome c - - - 0.00000000001118 77.0
HKD1_k127_4553208_7 - - - - 0.0000005483 56.0
HKD1_k127_4568235_0 SMART AAA ATPase - - - 4.466e-220 689.0
HKD1_k127_4568235_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 589.0
HKD1_k127_4568235_10 Participates in transcription elongation, termination and antitermination K02601,K05785 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000606 223.0
HKD1_k127_4568235_11 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000009263 218.0
HKD1_k127_4568235_12 - - - - 0.0000000000000000000000000000000000000000000000000000002532 202.0
HKD1_k127_4568235_13 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000528 176.0
HKD1_k127_4568235_14 PFAM low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.000000000000000000000000000000001439 136.0
HKD1_k127_4568235_2 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 573.0
HKD1_k127_4568235_3 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 559.0
HKD1_k127_4568235_4 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 424.0
HKD1_k127_4568235_5 PFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 364.0
HKD1_k127_4568235_6 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 353.0
HKD1_k127_4568235_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 314.0
HKD1_k127_4568235_8 lipid binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007528 298.0
HKD1_k127_4568235_9 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000001812 252.0
HKD1_k127_458092_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5.485e-260 813.0
HKD1_k127_458092_1 Molydopterin dinucleotide binding domain - - - 2.796e-233 743.0
HKD1_k127_458092_10 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000001081 209.0
HKD1_k127_458092_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000001083 153.0
HKD1_k127_458092_12 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000001895 144.0
HKD1_k127_458092_13 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000891 94.0
HKD1_k127_458092_14 PFAM cytochrome c oxidase, subunit III K02276,K02299 - 1.9.3.1 0.000000273 57.0
HKD1_k127_458092_2 PFAM Polysulphide reductase, NrfD K00185 - - 4.076e-197 624.0
HKD1_k127_458092_3 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 329.0
HKD1_k127_458092_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 315.0
HKD1_k127_458092_5 Cytochrome c K02030,K17760,K19713 - 1.1.9.1,1.8.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 297.0
HKD1_k127_458092_6 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002018 289.0
HKD1_k127_458092_7 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000006232 205.0
HKD1_k127_458092_8 ThiJ/PfpI family-like K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000659 207.0
HKD1_k127_458092_9 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000009588 201.0
HKD1_k127_4609132_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 467.0
HKD1_k127_4609132_1 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 355.0
HKD1_k127_4609132_2 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001631 273.0
HKD1_k127_4609132_3 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002166 259.0
HKD1_k127_4609132_4 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000000000000000264 194.0
HKD1_k127_4609132_6 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000001316 144.0
HKD1_k127_4636713_0 ATP synthesis coupled electron transport K00336 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 7.612e-310 970.0
HKD1_k127_4636713_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.918e-225 719.0
HKD1_k127_4636713_10 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 431.0
HKD1_k127_4636713_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 417.0
HKD1_k127_4636713_12 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 415.0
HKD1_k127_4636713_13 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 347.0
HKD1_k127_4636713_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 290.0
HKD1_k127_4636713_15 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 289.0
HKD1_k127_4636713_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007112 269.0
HKD1_k127_4636713_17 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003526 255.0
HKD1_k127_4636713_18 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000138 258.0
HKD1_k127_4636713_19 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000001415 235.0
HKD1_k127_4636713_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.362e-213 681.0
HKD1_k127_4636713_20 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000001949 218.0
HKD1_k127_4636713_21 peptidoglycan turnover - - - 0.000000000000000000000000000000000000000000000000000000001962 217.0
HKD1_k127_4636713_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000002069 204.0
HKD1_k127_4636713_23 regulatory protein, arsR - - - 0.0000000000000000000000000000000000000000000000000000005862 199.0
HKD1_k127_4636713_24 Nickel-containing superoxide dismutase K00518 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.15.1.1 0.000000000000000000000000000000000000000000000000000001091 196.0
HKD1_k127_4636713_25 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000006874 192.0
HKD1_k127_4636713_26 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000008959 207.0
HKD1_k127_4636713_27 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000001402 162.0
HKD1_k127_4636713_28 regulatory protein, arsR - - - 0.00000000000000000000000000000000006273 140.0
HKD1_k127_4636713_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000367 127.0
HKD1_k127_4636713_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 4.661e-213 672.0
HKD1_k127_4636713_30 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.0000000000000000000000118 105.0
HKD1_k127_4636713_31 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000002993 108.0
HKD1_k127_4636713_32 signal peptide processing K13280 - 3.4.21.89 0.0000000000000000001501 93.0
HKD1_k127_4636713_33 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.000000000000000002627 92.0
HKD1_k127_4636713_34 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000001499 87.0
HKD1_k127_4636713_35 antisigma factor binding K04749,K06378 - - 0.000000000002695 71.0
HKD1_k127_4636713_36 DinB superfamily - - - 0.0000000424 61.0
HKD1_k127_4636713_38 Protein of unknown function (DUF402) K07586 - - 0.0000002099 59.0
HKD1_k127_4636713_39 - - - - 0.000006058 51.0
HKD1_k127_4636713_4 PFAM cell divisionFtsK SpoIIIE K03466 - - 6.558e-209 674.0
HKD1_k127_4636713_40 Polyketide cyclase / dehydrase and lipid transport - - - 0.00002531 53.0
HKD1_k127_4636713_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007005 602.0
HKD1_k127_4636713_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 592.0
HKD1_k127_4636713_7 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 531.0
HKD1_k127_4636713_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 520.0
HKD1_k127_4636713_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 471.0
HKD1_k127_4639409_0 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008145 261.0
HKD1_k127_4639409_1 FR47-like protein - - - 0.00000000000000000000000000000001342 138.0
HKD1_k127_4639409_2 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000007647 115.0
HKD1_k127_4639409_3 2-dehydropantoate 2-reductase activity K00077 - 1.1.1.169 0.0000000851 61.0
HKD1_k127_4639409_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00005925 55.0
HKD1_k127_4655482_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0 1382.0
HKD1_k127_4655482_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 6.895e-229 717.0
HKD1_k127_4655482_10 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000005534 255.0
HKD1_k127_4655482_11 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000006143 199.0
HKD1_k127_4655482_12 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000001353 145.0
HKD1_k127_4655482_13 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000102 136.0
HKD1_k127_4655482_2 Alcohol dehydrogenase GroES-like domain K22231 - - 3.191e-198 623.0
HKD1_k127_4655482_3 PfkB domain protein K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 559.0
HKD1_k127_4655482_4 creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 507.0
HKD1_k127_4655482_5 lactate racemase activity K22373 - 5.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 475.0
HKD1_k127_4655482_6 ATPase with chaperone activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 364.0
HKD1_k127_4655482_7 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 335.0
HKD1_k127_4655482_8 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 294.0
HKD1_k127_4655482_9 Xylose isomerase-like TIM barrel K22233 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002254 261.0
HKD1_k127_4749823_0 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 364.0
HKD1_k127_4749823_1 ABC transporter ATPase K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 319.0
HKD1_k127_4749823_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000001359 199.0
HKD1_k127_4802693_0 beta-galactosidase activity K01190,K17624 - 3.2.1.23,3.2.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007811 501.0
HKD1_k127_4802693_1 Beta-lactamase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 506.0
HKD1_k127_4802693_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004509 278.0
HKD1_k127_4802693_12 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000004495 166.0
HKD1_k127_4802693_14 - - - - 0.0000000000000000134 86.0
HKD1_k127_4802693_15 Tellurite resistance protein TehB - - - 0.00000000002344 73.0
HKD1_k127_4802693_16 Glycosyl transferase, family 2 K20444 - - 0.00000000004998 78.0
HKD1_k127_4802693_17 Tetratricopeptide TPR_2 repeat protein - - - 0.000002236 63.0
HKD1_k127_4802693_18 DinB superfamily - - - 0.0001383 51.0
HKD1_k127_4802693_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 515.0
HKD1_k127_4802693_3 TIGRFAM RNA polymerase sigma-54 factor, RpoN K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 475.0
HKD1_k127_4802693_4 oxidoreductase activity K11089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 396.0
HKD1_k127_4802693_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 390.0
HKD1_k127_4802693_6 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 353.0
HKD1_k127_4802693_7 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 344.0
HKD1_k127_4802693_8 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 344.0
HKD1_k127_4802693_9 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 333.0
HKD1_k127_5021798_0 - - - - 0.000000000000000000001472 102.0
HKD1_k127_5021798_1 - - - - 0.000001276 57.0
HKD1_k127_5045557_0 glycerophosphodiester phosphodiesterase K01124 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008081,GO:0008150,GO:0008593,GO:0008889,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0010720,GO:0012505,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0021510,GO:0021515,GO:0021517,GO:0021522,GO:0021895,GO:0021953,GO:0022008,GO:0023051,GO:0023057,GO:0030030,GO:0030154,GO:0030182,GO:0030424,GO:0030900,GO:0031175,GO:0031984,GO:0032501,GO:0032502,GO:0036477,GO:0040034,GO:0042175,GO:0042578,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045746,GO:0045787,GO:0047389,GO:0048468,GO:0048471,GO:0048505,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051239,GO:0051240,GO:0051726,GO:0051960,GO:0051962,GO:0060284,GO:0060322,GO:0065007,GO:0071840,GO:0097038,GO:0097458,GO:0098827,GO:0120025,GO:0120036,GO:2000026 3.1.4.43 0.0000000000000000000000000000000000000000000000000000001523 213.0
HKD1_k127_5045557_1 PFAM Two component regulator propeller - - - 0.00000000000000000000000000000000002453 156.0
HKD1_k127_5045557_2 to Saccharomyces cerevisiae TAF5 (YBR198C) K03130 GO:0000123,GO:0000124,GO:0000428,GO:0000988,GO:0000990,GO:0000991,GO:0003674,GO:0003682,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005667,GO:0005669,GO:0006139,GO:0006325,GO:0006338,GO:0006351,GO:0006352,GO:0006355,GO:0006357,GO:0006366,GO:0006367,GO:0006464,GO:0006473,GO:0006475,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016043,GO:0016070,GO:0016569,GO:0016570,GO:0016573,GO:0016591,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0022607,GO:0030880,GO:0031248,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032182,GO:0032774,GO:0032947,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0043130,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044798,GO:0046483,GO:0046695,GO:0050789,GO:0050794,GO:0051123,GO:0051171,GO:0051252,GO:0051276,GO:0055029,GO:0060255,GO:0061695,GO:0065003,GO:0065004,GO:0065007,GO:0070013,GO:0070461,GO:0070897,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0090304,GO:0090575,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1902493,GO:1902494,GO:1903506,GO:1905368,GO:1990234,GO:2000112,GO:2001141 - 0.0008996 43.0
HKD1_k127_5052357_0 Cation transporter/ATPase, N-terminus - - - 7.358e-274 871.0
HKD1_k127_5052357_1 Prolyl oligopeptidase family - - - 9.064e-205 655.0
HKD1_k127_5052357_10 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003127 273.0
HKD1_k127_5052357_11 histidine kinase A domain protein K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001826 272.0
HKD1_k127_5052357_12 Putative NAD(P)-binding K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000191 261.0
HKD1_k127_5052357_13 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000865 240.0
HKD1_k127_5052357_14 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000002238 233.0
HKD1_k127_5052357_15 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000008006 219.0
HKD1_k127_5052357_16 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000002297 188.0
HKD1_k127_5052357_17 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000007344 170.0
HKD1_k127_5052357_18 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000000000000975 147.0
HKD1_k127_5052357_19 Amino acid permease - - - 0.000000000000000002253 100.0
HKD1_k127_5052357_2 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 518.0
HKD1_k127_5052357_21 Amino acid permease - - - 0.0000000000002163 83.0
HKD1_k127_5052357_3 aminopeptidase activity K01179,K01269 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 494.0
HKD1_k127_5052357_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 459.0
HKD1_k127_5052357_5 PFAM luciferase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 378.0
HKD1_k127_5052357_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 334.0
HKD1_k127_5052357_7 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 306.0
HKD1_k127_5052357_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000001251 269.0
HKD1_k127_5061390_0 cobalamin binding - - - 8.118e-261 812.0
HKD1_k127_5061390_1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 575.0
HKD1_k127_5061390_10 cobalamin binding - - - 0.000000000000000000000000000000000000000000000000000000000000005185 229.0
HKD1_k127_5061390_11 PFAM Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000009182 228.0
HKD1_k127_5061390_12 Uncharacterized protein family UPF0029 K00560,K01271 - 2.1.1.45,3.4.13.9 0.00000000000000000000000000000000000000000000000000000001137 205.0
HKD1_k127_5061390_13 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000001857 185.0
HKD1_k127_5061390_14 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000001139 163.0
HKD1_k127_5061390_15 chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000000000000009195 154.0
HKD1_k127_5061390_16 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000001954 167.0
HKD1_k127_5061390_17 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000008901 168.0
HKD1_k127_5061390_18 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000001207 155.0
HKD1_k127_5061390_19 Protease prsW family - - - 0.00000000000000000000000000003316 136.0
HKD1_k127_5061390_2 Transmembrane region of lysyl-tRNA synthetase K07027,K14205 - 2.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 579.0
HKD1_k127_5061390_20 Cyclic-di-AMP receptor - - - 0.00000000000000000000000009121 110.0
HKD1_k127_5061390_21 Protein of unknown function (DUF3052) - - - 0.000000000000000000000005328 106.0
HKD1_k127_5061390_24 Belongs to the UPF0250 family K09158 - - 0.00000000000000000006548 91.0
HKD1_k127_5061390_25 Cyclic-di-AMP receptor - - - 0.0000000000000000001219 93.0
HKD1_k127_5061390_26 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000004407 78.0
HKD1_k127_5061390_27 4Fe-4S binding domain - - - 0.0000000005384 63.0
HKD1_k127_5061390_3 Aldo/keto reductase family K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 527.0
HKD1_k127_5061390_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 383.0
HKD1_k127_5061390_5 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 373.0
HKD1_k127_5061390_6 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 368.0
HKD1_k127_5061390_7 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004281 268.0
HKD1_k127_5061390_8 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005044 246.0
HKD1_k127_5061390_9 adenosine deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000007063 237.0
HKD1_k127_5072712_0 PFAM glycosyl transferase, family 51 - - - 0.0 1221.0
HKD1_k127_5072712_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1071.0
HKD1_k127_5072712_10 N-4 methylation of cytosine K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 443.0
HKD1_k127_5072712_11 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 353.0
HKD1_k127_5072712_12 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 326.0
HKD1_k127_5072712_13 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 324.0
HKD1_k127_5072712_14 inorganic diphosphatase activity K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 327.0
HKD1_k127_5072712_15 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 319.0
HKD1_k127_5072712_16 PFAM Thioredoxin domain K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 299.0
HKD1_k127_5072712_17 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 294.0
HKD1_k127_5072712_18 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001263 292.0
HKD1_k127_5072712_19 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002595 255.0
HKD1_k127_5072712_2 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0 1047.0
HKD1_k127_5072712_20 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000266 252.0
HKD1_k127_5072712_21 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004513 253.0
HKD1_k127_5072712_22 Hydrolase, alpha beta domain protein K01048 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000002624 238.0
HKD1_k127_5072712_23 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000001973 231.0
HKD1_k127_5072712_24 Acetyltransferase (GNAT) domain K03817 - - 0.000000000000000000000000000000000000000000000000000000000000001422 224.0
HKD1_k127_5072712_25 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000002878 196.0
HKD1_k127_5072712_26 - - - - 0.000000000000000000000000000000000000000000000000000006068 192.0
HKD1_k127_5072712_27 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000000002464 193.0
HKD1_k127_5072712_28 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000003474 190.0
HKD1_k127_5072712_29 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000004417 194.0
HKD1_k127_5072712_3 ABC transporter transmembrane region K06147 - - 2.036e-259 811.0
HKD1_k127_5072712_30 MaoC like domain - - - 0.000000000000000000000000000000000000000000008387 167.0
HKD1_k127_5072712_31 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000002835 158.0
HKD1_k127_5072712_32 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000005538 145.0
HKD1_k127_5072712_4 ABC transporter transmembrane region K06147 - - 5.475e-249 781.0
HKD1_k127_5072712_5 adenosylmethionine-8-amino-7-oxononanoate transaminase activity K15372 - 2.6.1.55 3.417e-216 678.0
HKD1_k127_5072712_6 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 3.096e-213 676.0
HKD1_k127_5072712_7 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 537.0
HKD1_k127_5072712_8 RNA-binding PUA-like domain of methyltransferase RsmF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 457.0
HKD1_k127_5075117_0 PFAM multicopper oxidase type 2 - - - 2.412e-279 875.0
HKD1_k127_5075117_1 carbohydrate transport K02027,K17244 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 438.0
HKD1_k127_5075117_2 PFAM ROK family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 379.0
HKD1_k127_5075117_3 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K10118,K10233,K15771,K17245 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 362.0
HKD1_k127_5075117_4 glycerophosphodiester transmembrane transport K17246 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000176 280.0
HKD1_k127_508234_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 8.059e-196 625.0
HKD1_k127_508234_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 627.0
HKD1_k127_508234_10 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000527 230.0
HKD1_k127_508234_11 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000002005 204.0
HKD1_k127_508234_12 PFAM Exonuclease, RNase T and DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000001798 194.0
HKD1_k127_508234_13 acetyltransferase - - - 0.00000000000000000000000000000000000000000000001051 181.0
HKD1_k127_508234_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000008836 170.0
HKD1_k127_508234_15 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000000000000000000000000000000000002328 169.0
HKD1_k127_508234_16 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000005929 171.0
HKD1_k127_508234_17 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000008398 153.0
HKD1_k127_508234_18 UTRA domain K03710 - - 0.0000000000000000000000000000000000001997 151.0
HKD1_k127_508234_19 thiolester hydrolase activity - - - 0.00000000000000000000000001016 121.0
HKD1_k127_508234_2 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 483.0
HKD1_k127_508234_20 carboxylic ester hydrolase activity - - - 0.00000000000000000000000002212 119.0
HKD1_k127_508234_21 Anti-sigma-K factor rskA - - - 0.0000000000000000000000154 109.0
HKD1_k127_508234_22 EXOIII K02342 - 2.7.7.7 0.00000000000000009911 87.0
HKD1_k127_508234_23 PFAM Protein kinase domain - - - 0.00000000000001138 88.0
HKD1_k127_508234_24 PspC domain - - - 0.000000000001378 72.0
HKD1_k127_508234_25 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000001797 64.0
HKD1_k127_508234_26 F420H(2)-dependent quinone reductase - - - 0.000000003092 66.0
HKD1_k127_508234_27 Heat shock protein DnaJ domain protein - - - 0.0000001109 62.0
HKD1_k127_508234_28 sugar isomerase K00820 - 2.6.1.16 0.00001442 49.0
HKD1_k127_508234_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 431.0
HKD1_k127_508234_4 N-terminal TM domain of oligopeptide transport permease C K02031,K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 352.0
HKD1_k127_508234_5 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 347.0
HKD1_k127_508234_6 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K02182 - 6.2.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 340.0
HKD1_k127_508234_7 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000108 276.0
HKD1_k127_508234_8 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001537 268.0
HKD1_k127_508234_9 YoaP-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000004645 244.0
HKD1_k127_5132354_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 368.0
HKD1_k127_5132354_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 375.0
HKD1_k127_5132354_2 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000239 264.0
HKD1_k127_5132354_3 PFAM Mechanosensitive ion channel K03442,K22044 - - 0.00000000000000000000000000000000000000000004172 171.0
HKD1_k127_5132354_4 Tetratricopeptide repeat K12600 - - 0.000000000000000000000000000000000000000009558 175.0
HKD1_k127_5137545_0 Serine carboxypeptidase - - - 4.962e-210 663.0
HKD1_k127_5137545_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 492.0
HKD1_k127_5137545_11 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000003655 112.0
HKD1_k127_5137545_13 Protein of unknown function (DUF1706) - - - 0.000000000000000001322 93.0
HKD1_k127_5137545_14 integral membrane protein K00728 - 2.4.1.109 0.0000000003531 72.0
HKD1_k127_5137545_2 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 430.0
HKD1_k127_5137545_3 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 344.0
HKD1_k127_5137545_4 Glycosyltransferase family 28 N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 338.0
HKD1_k127_5137545_5 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 312.0
HKD1_k127_5137545_6 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000000000000000003815 213.0
HKD1_k127_5137545_7 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000008654 151.0
HKD1_k127_5137545_8 Cell envelope-related transcriptional attenuator domain - - - 0.000000000000000000000000003928 124.0
HKD1_k127_5137545_9 Cell envelope-like function transcriptional attenuator common domain protein - - - 0.000000000000000000000000295 119.0
HKD1_k127_5165529_0 TIGRFAM MazG family protein K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 573.0
HKD1_k127_5165529_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 556.0
HKD1_k127_5165529_10 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000004467 268.0
HKD1_k127_5165529_11 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000051 252.0
HKD1_k127_5165529_12 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000003296 255.0
HKD1_k127_5165529_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000154 239.0
HKD1_k127_5165529_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000006401 215.0
HKD1_k127_5165529_15 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000007791 215.0
HKD1_k127_5165529_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000741 211.0
HKD1_k127_5165529_17 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000008714 206.0
HKD1_k127_5165529_18 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003372 190.0
HKD1_k127_5165529_19 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000001292 180.0
HKD1_k127_5165529_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 492.0
HKD1_k127_5165529_20 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000007447 177.0
HKD1_k127_5165529_21 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000001535 176.0
HKD1_k127_5165529_22 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000001629 171.0
HKD1_k127_5165529_23 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000004276 160.0
HKD1_k127_5165529_24 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000003729 157.0
HKD1_k127_5165529_25 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000002379 156.0
HKD1_k127_5165529_26 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000003381 145.0
HKD1_k127_5165529_27 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000002449 125.0
HKD1_k127_5165529_28 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000005024 114.0
HKD1_k127_5165529_29 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000001901 86.0
HKD1_k127_5165529_3 Enoyl-(Acyl carrier protein) reductase K10780 - 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 343.0
HKD1_k127_5165529_30 Raf kinase inhibitor-like protein, YbhB YbcL family K06910 - - 0.0000000000000004765 78.0
HKD1_k127_5165529_31 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000006459 68.0
HKD1_k127_5165529_32 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000003022 63.0
HKD1_k127_5165529_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 338.0
HKD1_k127_5165529_5 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 301.0
HKD1_k127_5165529_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 298.0
HKD1_k127_5165529_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 287.0
HKD1_k127_5165529_8 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 280.0
HKD1_k127_5165529_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006267 278.0
HKD1_k127_5217152_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1049.0
HKD1_k127_5217152_1 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 592.0
HKD1_k127_5217152_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000242 292.0
HKD1_k127_5217152_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000003037 160.0
HKD1_k127_5223632_0 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 595.0
HKD1_k127_5223632_1 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 594.0
HKD1_k127_5223632_10 NUDIX domain - - - 0.000000000000000000000000001198 117.0
HKD1_k127_5223632_11 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000002256 115.0
HKD1_k127_5223632_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000002156 85.0
HKD1_k127_5223632_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 483.0
HKD1_k127_5223632_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 392.0
HKD1_k127_5223632_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 384.0
HKD1_k127_5223632_5 PFAM Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 312.0
HKD1_k127_5223632_6 ROK family K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 301.0
HKD1_k127_5223632_7 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000001764 210.0
HKD1_k127_5223632_8 CYTH domain - - - 0.00000000000000000000000000000000000000000000003856 174.0
HKD1_k127_5223632_9 - - - - 0.00000000000000000000000000000000001085 139.0
HKD1_k127_5231953_0 Two component regulator propeller - - - 7.99e-214 706.0
HKD1_k127_5231953_1 Sucrose phosphorylase K00690,K21350 GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758 2.4.1.329,2.4.1.7 1.563e-206 653.0
HKD1_k127_5231953_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000406 226.0
HKD1_k127_5231953_11 COGs COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2 - - - 0.0000000000000000000000000000000000000000000000000000000003706 209.0
HKD1_k127_5231953_12 - - - - 0.00000000000000000000000000000000000000000000003201 175.0
HKD1_k127_5231953_13 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000001333 165.0
HKD1_k127_5231953_14 sequence-specific DNA binding K07729 - - 0.000000000000000000000000004723 111.0
HKD1_k127_5231953_15 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000759 104.0
HKD1_k127_5231953_16 response regulator K07689 - - 0.0000000000000000000477 95.0
HKD1_k127_5231953_18 PFAM Transposase DDE domain - - - 0.0000000000107 66.0
HKD1_k127_5231953_19 WD domain, G-beta repeat - - - 0.00000000001525 69.0
HKD1_k127_5231953_2 Bacterial extracellular solute-binding protein K02027,K10117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 501.0
HKD1_k127_5231953_20 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000002301 61.0
HKD1_k127_5231953_3 PFAM Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 486.0
HKD1_k127_5231953_4 Glycosyltransferase family 28 N-terminal domain K05841 - 2.4.1.173 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 427.0
HKD1_k127_5231953_5 Binding-protein-dependent transport system inner membrane component K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 368.0
HKD1_k127_5231953_6 Binding-protein-dependent transport system inner membrane component K10119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 366.0
HKD1_k127_5231953_7 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 311.0
HKD1_k127_5231953_8 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 302.0
HKD1_k127_5231953_9 dihydrofolate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 289.0
HKD1_k127_5232936_0 Alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 299.0
HKD1_k127_5232936_1 PFAM bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000007537 209.0
HKD1_k127_5232936_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000007337 201.0
HKD1_k127_5232936_3 bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000006889 171.0
HKD1_k127_5232936_4 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000001296 171.0
HKD1_k127_5232936_5 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000004833 97.0
HKD1_k127_523854_0 Glycyl-tRNA synthetase alpha subunit K14164 - 6.1.1.14 0.0 1219.0
HKD1_k127_523854_1 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 1.542e-316 979.0
HKD1_k127_523854_10 - - - - 0.0000000000000000000000000065 114.0
HKD1_k127_523854_11 Domain of unknown function (DUF3786) - - - 0.000000000000000006731 94.0
HKD1_k127_523854_13 - - - - 0.000000000008457 69.0
HKD1_k127_523854_14 nitrogen fixation - - - 0.00001784 57.0
HKD1_k127_523854_2 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 551.0
HKD1_k127_523854_3 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 434.0
HKD1_k127_523854_4 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 367.0
HKD1_k127_523854_5 NAD synthase K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 294.0
HKD1_k127_523854_6 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002741 283.0
HKD1_k127_523854_7 Flavodoxin-like fold K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000006191 259.0
HKD1_k127_523854_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001601 267.0
HKD1_k127_523854_9 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000003809 128.0
HKD1_k127_5248730_0 Extracellular solute-binding protein K02055,K11069 - - 1.472e-197 621.0
HKD1_k127_5248730_1 ATPase activity K02052,K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 437.0
HKD1_k127_5248730_2 PFAM binding-protein-dependent transport systems inner membrane component K02054,K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 387.0
HKD1_k127_5248730_3 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 368.0
HKD1_k127_5248730_4 ABC transporter (permease) K02053 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 364.0
HKD1_k127_5248730_5 non-specific phospholipase K01114 GO:0003674,GO:0003824,GO:0003993,GO:0004620,GO:0004629,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009405,GO:0009987,GO:0016042,GO:0016298,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0034480,GO:0035821,GO:0042578,GO:0044003,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044403,GO:0044419,GO:0046434,GO:0051701,GO:0051704,GO:0051817,GO:0052008,GO:0052043,GO:0052111,GO:0052185,GO:0052188,GO:0052368,GO:0071704,GO:1901575 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 317.0
HKD1_k127_5248730_6 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000009965 222.0
HKD1_k127_5248730_8 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000000001817 161.0
HKD1_k127_5248730_9 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.00000000000000000000000006076 117.0
HKD1_k127_5375545_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1498.0
HKD1_k127_5375545_1 Family 4 glycosyl hydrolase K01222,K07406 - 3.2.1.22,3.2.1.86 5.778e-233 727.0
HKD1_k127_5375545_10 Protein of unknown function (DUF1214) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006581 270.0
HKD1_k127_5375545_11 Ferritin-like - - - 0.000000000000000000000000000000000000000000000000000000001005 209.0
HKD1_k127_5375545_12 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000001829 172.0
HKD1_k127_5375545_14 PFAM Stage V sporulation protein S K06416 - - 0.0000000000000000000000000000004643 124.0
HKD1_k127_5375545_15 - - - - 0.000000000000000000000000000038 122.0
HKD1_k127_5375545_16 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000001198 108.0
HKD1_k127_5375545_17 - - - - 0.000000000000000000004197 100.0
HKD1_k127_5375545_18 Alpha/beta hydrolase family - - - 0.00000000000000000004149 92.0
HKD1_k127_5375545_19 - - - - 0.0000000000000009872 80.0
HKD1_k127_5375545_2 PFAM ABC transporter related K06158 - - 8.552e-212 677.0
HKD1_k127_5375545_22 Alpha/beta hydrolase family - - - 0.0000006155 51.0
HKD1_k127_5375545_23 Belongs to the 'phage' integrase family - - - 0.000002199 53.0
HKD1_k127_5375545_24 helix_turn_helix, Lux Regulon K02282,K07696 - - 0.000009077 56.0
HKD1_k127_5375545_25 Phage integrase, N-terminal SAM-like domain - - - 0.0008481 45.0
HKD1_k127_5375545_3 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 452.0
HKD1_k127_5375545_4 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 418.0
HKD1_k127_5375545_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 414.0
HKD1_k127_5375545_6 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008193 400.0
HKD1_k127_5375545_7 fad dependent oxidoreductase K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 391.0
HKD1_k127_5375545_8 Protein of unknown function (DUF1214) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 320.0
HKD1_k127_5375545_9 Protein of unknown function (DUF4256) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 304.0
HKD1_k127_5380072_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1289.0
HKD1_k127_5380072_1 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 1.904e-199 635.0
HKD1_k127_5380072_10 Na H antiporter K03315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 466.0
HKD1_k127_5380072_11 Reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 447.0
HKD1_k127_5380072_12 Mycobacterial 4 TMS phage holin, superfamily IV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 447.0
HKD1_k127_5380072_13 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 435.0
HKD1_k127_5380072_14 Neurotransmitter-gated ion-channel ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 429.0
HKD1_k127_5380072_15 Peptidase family M28 K13049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 413.0
HKD1_k127_5380072_16 H( )-transporting two-sector ATPase K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 391.0
HKD1_k127_5380072_17 PFAM Polyphosphate kinase 2 K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 371.0
HKD1_k127_5380072_18 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 357.0
HKD1_k127_5380072_19 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 358.0
HKD1_k127_5380072_2 COG0659 Sulfate permease and related transporters (MFS superfamily) - - - 1.002e-194 623.0
HKD1_k127_5380072_20 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 348.0
HKD1_k127_5380072_21 PFAM alanine racemase domain protein K20757 - 4.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 339.0
HKD1_k127_5380072_22 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 301.0
HKD1_k127_5380072_23 Bacterial sugar transferase K19428 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001102 279.0
HKD1_k127_5380072_24 Dehydrogenase E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002652 275.0
HKD1_k127_5380072_25 Putative threonine/serine exporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001932 280.0
HKD1_k127_5380072_26 response regulator, receiver K02479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001764 257.0
HKD1_k127_5380072_27 zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000001728 240.0
HKD1_k127_5380072_28 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000007437 237.0
HKD1_k127_5380072_29 Transcriptional regulator K03603,K05799,K22104 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0019395,GO:0019752,GO:0030258,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032787,GO:0032991,GO:0032993,GO:0034440,GO:0042304,GO:0043436,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045723,GO:0045833,GO:0045834,GO:0045892,GO:0045893,GO:0045923,GO:0045934,GO:0045935,GO:0045936,GO:0046889,GO:0046890,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051252,GO:0051253,GO:0051254,GO:0055114,GO:0060255,GO:0062012,GO:0062013,GO:0065007,GO:0071071,GO:0071072,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1903725,GO:1903726,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000005382 231.0
HKD1_k127_5380072_3 Amidinotransferase K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 611.0
HKD1_k127_5380072_30 LURP-one-related - - - 0.00000000000000000000000000000000000000000000000000000000000000005439 228.0
HKD1_k127_5380072_31 spore germination K03298 - - 0.0000000000000000000000000000000000000000000000000000000000000002154 231.0
HKD1_k127_5380072_32 response regulator, receiver K02479 - - 0.000000000000000000000000000000000000000000000000000000000000005465 224.0
HKD1_k127_5380072_33 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000003104 216.0
HKD1_k127_5380072_34 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02480 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000002887 235.0
HKD1_k127_5380072_35 Protein of unknown function (DUF1269) - - - 0.0000000000000000000000000000000000000000000000000000000002509 206.0
HKD1_k127_5380072_36 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000004281 200.0
HKD1_k127_5380072_37 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000004876 197.0
HKD1_k127_5380072_38 zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000001382 197.0
HKD1_k127_5380072_39 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000002492 215.0
HKD1_k127_5380072_4 C4-dicarboxylate anaerobic carrier - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 614.0
HKD1_k127_5380072_40 Transposase K02557,K03406,K07484,K13924,K21471 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000001606 206.0
HKD1_k127_5380072_41 Chloride channel - - - 0.0000000000000000000000000000000000000000000000001862 192.0
HKD1_k127_5380072_42 LURP-one-related - - - 0.000000000000000000000000000000000000000000005491 170.0
HKD1_k127_5380072_43 membrane protein of uknown function UCP014873 - - - 0.00000000000000000000000000000000000000000001015 173.0
HKD1_k127_5380072_44 PFAM Ribonuclease BN-like family K07058 - - 0.000000000000000000000000000000000000000002623 166.0
HKD1_k127_5380072_45 Protein of unknown function (DUF1269) - - - 0.000000000000000000000000000000000000000006924 159.0
HKD1_k127_5380072_46 Domain of unknown function (DUF4332) - - - 0.00000000000000000000000000000000000000002751 168.0
HKD1_k127_5380072_47 AI-2E family transporter - - - 0.00000000000000000000000000000000000000006831 165.0
HKD1_k127_5380072_48 META domain - - - 0.00000000000000000000000000000000000004188 158.0
HKD1_k127_5380072_49 Domain of unknown function (DUF4332) - - - 0.000000000000000000000000000000000007439 155.0
HKD1_k127_5380072_5 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 615.0
HKD1_k127_5380072_50 Ion transport protein K10716 - - 0.00000000000000000000000000000000004313 145.0
HKD1_k127_5380072_51 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000003327 140.0
HKD1_k127_5380072_52 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000001949 141.0
HKD1_k127_5380072_53 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000006531 138.0
HKD1_k127_5380072_54 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000001703 134.0
HKD1_k127_5380072_55 Protein of unknown function (DUF1269) - - - 0.00000000000000000000000000004954 123.0
HKD1_k127_5380072_56 membrane protein of uknown function UCP014873 - - - 0.000000000000000000000000000248 119.0
HKD1_k127_5380072_57 membrane protein of uknown function UCP014873 - - - 0.000000000000000000000000002331 117.0
HKD1_k127_5380072_58 - - - - 0.000000000000000000000000003896 113.0
HKD1_k127_5380072_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 545.0
HKD1_k127_5380072_60 helix_turn_helix, Lux Regulon K07693 - - 0.000000000000000000000007699 106.0
HKD1_k127_5380072_61 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000007073 116.0
HKD1_k127_5380072_62 Short repeat of unknown function (DUF308) - - - 0.000000000000000000001128 102.0
HKD1_k127_5380072_63 RDD family - - - 0.0000000000000000006076 93.0
HKD1_k127_5380072_64 META domain - - - 0.000000000000000001305 102.0
HKD1_k127_5380072_65 Protein of unknown function (DUF1269) - - - 0.000000000000000001668 94.0
HKD1_k127_5380072_68 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000000000000002398 86.0
HKD1_k127_5380072_69 META domain K03668 - - 0.0000000000000001417 95.0
HKD1_k127_5380072_7 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 542.0
HKD1_k127_5380072_72 Histidine kinase K07711 - 2.7.13.3 0.000000000000002818 89.0
HKD1_k127_5380072_73 - - - - 0.00000000000001024 78.0
HKD1_k127_5380072_74 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000002666 88.0
HKD1_k127_5380072_75 helix_turn_helix, Lux Regulon - - - 0.0000000005131 65.0
HKD1_k127_5380072_76 helix_turn_helix, Lux Regulon K07684 - - 0.0000000007025 64.0
HKD1_k127_5380072_77 sh3 domain protein K01448,K04771 - 3.4.21.107,3.5.1.28 0.000000007499 68.0
HKD1_k127_5380072_78 SpoIIAA-like - - - 0.000000009245 61.0
HKD1_k127_5380072_79 HWE histidine kinase - - - 0.000005922 59.0
HKD1_k127_5380072_8 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 533.0
HKD1_k127_5380072_80 MFS/sugar transport protein K03292 - - 0.0009163 43.0
HKD1_k127_5380072_9 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 482.0
HKD1_k127_5392175_0 polysaccharide catabolic process K05991 - 3.2.1.123 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 538.0
HKD1_k127_5392175_1 PFAM Nucleotidyltransferase K07074 - - 0.0000000000000000000000000000000000000000000000000002805 188.0
HKD1_k127_5392175_2 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000001775 69.0
HKD1_k127_5399909_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 512.0
HKD1_k127_5399909_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 483.0
HKD1_k127_5399909_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 364.0
HKD1_k127_5399909_3 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 302.0
HKD1_k127_5399909_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000001118 171.0
HKD1_k127_5399909_5 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.00000000000000000000000000000000000000000003759 164.0
HKD1_k127_5399909_6 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.000000000000000000006597 93.0
HKD1_k127_5399909_7 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000000000000002021 80.0
HKD1_k127_5405398_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 368.0
HKD1_k127_5405398_1 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 308.0
HKD1_k127_5405398_2 - - - - 0.00000000000000000000000000008287 119.0
HKD1_k127_5405398_3 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000000000000341 94.0
HKD1_k127_54128_0 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 563.0
HKD1_k127_54128_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 557.0
HKD1_k127_54128_10 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000002944 261.0
HKD1_k127_54128_11 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000001019 190.0
HKD1_k127_54128_12 PHP-associated - - - 0.0000000000000000000000000000000000000000009258 165.0
HKD1_k127_54128_13 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.000000000000000000000000000000000000002297 154.0
HKD1_k127_54128_14 Transcriptional regulator, RpiR family - GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.0009561 48.0
HKD1_k127_54128_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 385.0
HKD1_k127_54128_3 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 374.0
HKD1_k127_54128_4 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 347.0
HKD1_k127_54128_5 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 338.0
HKD1_k127_54128_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 331.0
HKD1_k127_54128_7 PFAM PfkB domain protein K16328 - 2.7.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 326.0
HKD1_k127_54128_8 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 325.0
HKD1_k127_5413457_0 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 547.0
HKD1_k127_5413457_1 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 415.0
HKD1_k127_5413457_3 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000006346 223.0
HKD1_k127_5420394_0 pilus organization K02674,K07004 - - 3.078e-197 673.0
HKD1_k127_5420394_1 5'-nucleotidase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 482.0
HKD1_k127_5420394_2 Carboxylesterase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004361 296.0
HKD1_k127_5420394_4 - - - - 0.0000000001216 69.0
HKD1_k127_5420394_5 - - - - 0.0000000003699 68.0
HKD1_k127_5425101_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1051.0
HKD1_k127_5425101_1 Subtilase family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000001926 255.0
HKD1_k127_5425101_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001738 219.0
HKD1_k127_5425101_3 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000001104 218.0
HKD1_k127_5425101_4 Hep Hag repeat protein - - - 0.000000000000000000000000000000000000002749 170.0
HKD1_k127_5425101_5 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000001936 150.0
HKD1_k127_5425101_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000001307 124.0
HKD1_k127_5425101_7 Peptidase family M48 - - - 0.00000000000000000006306 100.0
HKD1_k127_5425101_8 Cell envelope-like function transcriptional attenuator common domain protein - - - 0.00000007795 61.0
HKD1_k127_5425101_9 - - - - 0.000355 46.0
HKD1_k127_5447988_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 3.218e-209 655.0
HKD1_k127_5447988_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 328.0
HKD1_k127_5447988_2 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000004475 266.0
HKD1_k127_5447988_3 ABC transporter K02006 - - 0.000000000000000000000000000000000000000000000001672 176.0
HKD1_k127_5447988_4 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.000000000005429 79.0
HKD1_k127_5472624_0 endonuclease exonuclease phosphatase K07004 - - 5.088e-229 748.0
HKD1_k127_5472624_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 485.0
HKD1_k127_5472624_10 Thioredoxin - - - 0.000000000000000000000000000001305 125.0
HKD1_k127_5472624_11 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000000001238 122.0
HKD1_k127_5472624_12 TfoX N-terminal domain - - - 0.000000000000000000000000005479 114.0
HKD1_k127_5472624_13 Streptomycin adenylyltransferase K05593 - - 0.0000000002301 62.0
HKD1_k127_5472624_14 integral membrane protein - - - 0.0000000004263 67.0
HKD1_k127_5472624_2 EamA-like transporter family K03298 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 312.0
HKD1_k127_5472624_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 305.0
HKD1_k127_5472624_4 Coenzyme F420 hydrogenase dehydrogenase, beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 307.0
HKD1_k127_5472624_5 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007106 286.0
HKD1_k127_5472624_6 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005965 266.0
HKD1_k127_5472624_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001288 258.0
HKD1_k127_5472624_8 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000064 247.0
HKD1_k127_5472624_9 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000129 190.0
HKD1_k127_5477714_0 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 503.0
HKD1_k127_5477714_1 HhH-GPD family K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 385.0
HKD1_k127_5477714_10 Transposase - - - 0.0000007176 53.0
HKD1_k127_5477714_11 Transposase - - - 0.000004629 49.0
HKD1_k127_5477714_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 359.0
HKD1_k127_5477714_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 319.0
HKD1_k127_5477714_4 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 304.0
HKD1_k127_5477714_6 - - - - 0.0000000000000000000000000000000000000000000004569 176.0
HKD1_k127_5477714_7 - - - - 0.00000000000000000000000000000002139 128.0
HKD1_k127_5477714_8 chromate transporter K07240 - - 0.0000000000000000000000000000003318 130.0
HKD1_k127_5477714_9 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000145 101.0
HKD1_k127_5479972_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000004638 184.0
HKD1_k127_5479972_1 Antibiotic biosynthesis monooxygenase - - - 0.0000000000003594 73.0
HKD1_k127_5479972_2 SPFH domain-Band 7 family - - - 0.0000001495 63.0
HKD1_k127_5500123_0 Glycosyltransferase family 36 K18675 - 2.4.1.280 0.0 1212.0
HKD1_k127_5500123_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 1.098e-246 782.0
HKD1_k127_5500123_2 collagen metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 473.0
HKD1_k127_5500123_3 ABC-type multidrug transport system ATPase K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 421.0
HKD1_k127_5500123_4 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 297.0
HKD1_k127_5500123_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001052 263.0
HKD1_k127_5500123_6 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000002179 226.0
HKD1_k127_5500123_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000001544 209.0
HKD1_k127_5500123_8 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000001144 206.0
HKD1_k127_5500123_9 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000000000000000000000000000000000000000000000001486 192.0
HKD1_k127_5572720_0 Putative metallopeptidase domain - - - 1.319e-216 690.0
HKD1_k127_5572720_1 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 568.0
HKD1_k127_5572720_10 Iron permease FTR1 family K07243 - - 0.000000000000000000000000000000000000000000000000000000000000004086 228.0
HKD1_k127_5572720_11 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000374 208.0
HKD1_k127_5572720_12 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000002599 199.0
HKD1_k127_5572720_13 - - - - 0.0000000000000000000000000000004333 135.0
HKD1_k127_5572720_14 Rdx family K07401 - - 0.000000000000002114 77.0
HKD1_k127_5572720_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 521.0
HKD1_k127_5572720_3 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 492.0
HKD1_k127_5572720_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 486.0
HKD1_k127_5572720_5 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 373.0
HKD1_k127_5572720_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008001 337.0
HKD1_k127_5572720_7 PFAM LmbE family protein K18455 - 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 317.0
HKD1_k127_5572720_8 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 306.0
HKD1_k127_5572720_9 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001567 257.0
HKD1_k127_5636574_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.822e-236 739.0
HKD1_k127_5636574_1 Terminase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 456.0
HKD1_k127_5636574_10 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000007973 107.0
HKD1_k127_5636574_11 GTPase activity K06949 - 3.1.3.100 0.0000000000000000000003655 104.0
HKD1_k127_5636574_12 Putative zincin peptidase - - - 0.000000000000000000007638 104.0
HKD1_k127_5636574_13 COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase) K07273 - - 0.0000000000000000000107 97.0
HKD1_k127_5636574_14 nuclease - - - 0.00000000000001702 87.0
HKD1_k127_5636574_16 nuclease K00590,K01174,K02027 - 2.1.1.113,3.1.31.1 0.0000001322 64.0
HKD1_k127_5636574_17 - - - - 0.0008582 48.0
HKD1_k127_5636574_2 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 395.0
HKD1_k127_5636574_3 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002006 283.0
HKD1_k127_5636574_4 dihydrofolate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005277 270.0
HKD1_k127_5636574_5 Steryl acetyl hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000239 257.0
HKD1_k127_5636574_6 Steryl acetyl hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000001225 246.0
HKD1_k127_5636574_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000004451 239.0
HKD1_k127_5636574_8 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000009319 193.0
HKD1_k127_5636574_9 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000006112 120.0
HKD1_k127_5658938_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 467.0
HKD1_k127_5658938_1 Two component transcriptional regulator, winged helix family K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001065 261.0
HKD1_k127_5658938_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000164 231.0
HKD1_k127_5658938_3 membrane - - - 0.00000000000000000000000000005979 123.0
HKD1_k127_5658938_4 - - - - 0.0000000000000145 75.0
HKD1_k127_5658938_5 - - - - 0.00000000003768 68.0
HKD1_k127_5658938_6 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.0000000005912 71.0
HKD1_k127_5679879_0 FAD dependent oxidoreductase central domain - - - 1.228e-274 866.0
HKD1_k127_5679879_1 Aminotransferase class I and II K00013,K00817 - 1.1.1.23,2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 572.0
HKD1_k127_5679879_10 FGGY family of carbohydrate kinase, N-terminal domain protein K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000001113 190.0
HKD1_k127_5679879_11 DeoR C terminal sensor domain K03436 - - 0.000000000000000000000000000000000000000000000000006056 192.0
HKD1_k127_5679879_12 - - - - 0.00000000000000000000000000000000000000000000001732 180.0
HKD1_k127_5679879_13 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.000000000000000000000000000000000000000000003174 171.0
HKD1_k127_5679879_14 amino acid - - - 0.0000000000000000000000000000000000000000000151 183.0
HKD1_k127_5679879_15 PFAM CBS domain containing protein - - - 0.00000000000007463 81.0
HKD1_k127_5679879_2 Belongs to the GcvT family K19191 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 491.0
HKD1_k127_5679879_3 Belongs to the group II decarboxylase family K01634 - 4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 475.0
HKD1_k127_5679879_4 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 444.0
HKD1_k127_5679879_5 phosphonoacetaldehyde hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 400.0
HKD1_k127_5679879_6 phosphate transporter K03306,K16322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 310.0
HKD1_k127_5679879_7 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000231 292.0
HKD1_k127_5679879_8 Choline/ethanolamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001382 246.0
HKD1_k127_5679879_9 Choline/ethanolamine kinase - - - 0.0000000000000000000000000000000000000000000000000000000002257 213.0
HKD1_k127_5737813_0 ECF transporter, substrate-specific component K16927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 291.0
HKD1_k127_5737813_1 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001025 280.0
HKD1_k127_5737813_2 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001382 269.0
HKD1_k127_5737813_3 KNTase C-terminal domain K17882 - - 0.0000000000000000000000000000000000000000000000000000000000000000007802 236.0
HKD1_k127_5737813_4 Zn peptidase - - - 0.000000000000000000000000000000000000000000004532 175.0
HKD1_k127_5737813_5 Phosphomannose isomerase type I K01809,K01840 - 5.3.1.8,5.4.2.8 0.0000000000000000000000000000000002196 150.0
HKD1_k127_5737813_6 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000001136 122.0
HKD1_k127_5737813_7 S-layer homology domain - - - 0.00000000000000001946 94.0
HKD1_k127_5803026_0 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009281 274.0
HKD1_k127_5803026_1 metalloendopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000006638 228.0
HKD1_k127_5803026_2 creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000005144 211.0
HKD1_k127_5803026_3 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000001697 142.0
HKD1_k127_5864068_0 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 554.0
HKD1_k127_5864068_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 322.0
HKD1_k127_5864068_2 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000001861 212.0
HKD1_k127_5864068_3 - K06039,K07092 - - 0.0000000000000000000000000000000000000000000001318 170.0
HKD1_k127_5864068_4 - - - - 0.000000000000000000000000000000000000000001119 168.0
HKD1_k127_5864068_5 - - - - 0.000000000008049 69.0
HKD1_k127_5864068_6 sulfur carrier activity K00549,K04085 - 2.1.1.14 0.00000006015 63.0
HKD1_k127_5864068_7 - - - - 0.000005058 57.0
HKD1_k127_5872888_0 PFAM type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 586.0
HKD1_k127_5872888_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 499.0
HKD1_k127_5872888_2 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 391.0
HKD1_k127_5872888_3 Domain of unknown function (DUF4291) - - - 0.000000000000000000000000000000000000001247 149.0
HKD1_k127_5872888_4 - - - - 0.00000000000000000000005162 101.0
HKD1_k127_5872888_5 Ankyrin repeat and protein kinase domain-containing protein 1-like - - - 0.0000000000000000005502 99.0
HKD1_k127_5872888_6 - - - - 0.0000000000001111 83.0
HKD1_k127_5872888_7 Domain of unknown function (DUF4291) - - - 0.0000000151 62.0
HKD1_k127_5872888_8 sterol carrier protein - - - 0.0003865 49.0
HKD1_k127_5889692_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.47e-305 944.0
HKD1_k127_5889692_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.497e-238 748.0
HKD1_k127_5889692_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.907e-226 706.0
HKD1_k127_5889692_3 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009151 322.0
HKD1_k127_5889692_4 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 288.0
HKD1_k127_5889692_5 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 285.0
HKD1_k127_5889692_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000001369 209.0
HKD1_k127_5889692_7 methyltransferase - - - 0.0000000000000000000000000000000000000002874 159.0
HKD1_k127_5955406_0 Belongs to the carbamoyltransferase HypF family K04656 - - 4.543e-262 829.0
HKD1_k127_5955406_1 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 533.0
HKD1_k127_5955406_2 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 422.0
HKD1_k127_5955406_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 340.0
HKD1_k127_5955406_4 Hydrogenase accessory protein HypB K03189,K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 292.0
HKD1_k127_5955406_5 Glycosyltransferase like family 2 K07011,K20444 - - 0.000000000000000000000000000000000000264 158.0
HKD1_k127_5955406_6 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000009979 141.0
HKD1_k127_5955406_7 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000000000004537 115.0
HKD1_k127_5955406_9 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000001623 52.0
HKD1_k127_6014579_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 371.0
HKD1_k127_6014579_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 323.0
HKD1_k127_6014579_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 309.0
HKD1_k127_6014579_3 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001288 291.0
HKD1_k127_6014579_4 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000001229 129.0
HKD1_k127_6048320_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1035.0
HKD1_k127_6048320_1 Required for chromosome condensation and partitioning K03529 - - 4.743e-307 980.0
HKD1_k127_6048320_10 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000003875 80.0
HKD1_k127_6048320_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 533.0
HKD1_k127_6048320_3 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 455.0
HKD1_k127_6048320_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 416.0
HKD1_k127_6048320_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007581 282.0
HKD1_k127_6048320_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002047 278.0
HKD1_k127_6048320_7 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002328 276.0
HKD1_k127_6048320_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000005422 208.0
HKD1_k127_6048320_9 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000003893 111.0
HKD1_k127_6073576_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 338.0
HKD1_k127_6073576_1 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000008475 235.0
HKD1_k127_6073576_2 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000001204 186.0
HKD1_k127_6073576_3 Putative membrane peptidase family (DUF2324) - - - 0.0000000000000000000000000000000000000000000000001619 187.0
HKD1_k127_6073576_4 amino acid activation for nonribosomal peptide biosynthetic process K01183 - 3.2.1.14 0.0001709 52.0
HKD1_k127_6167708_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 8.027e-277 859.0
HKD1_k127_6167708_1 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 1.012e-275 873.0
HKD1_k127_6167708_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 4.162e-222 694.0
HKD1_k127_6167708_3 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009911 492.0
HKD1_k127_6167708_4 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 444.0
HKD1_k127_6167708_5 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007961 246.0
HKD1_k127_6167708_6 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000006449 188.0
HKD1_k127_6167708_7 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000006076 171.0
HKD1_k127_6167708_8 Rubrerythrin - - - 0.00000000000000000000000000004621 122.0
HKD1_k127_6167708_9 MazG-like family - - - 0.0000000000000000000000000001649 117.0
HKD1_k127_6174915_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 1.395e-208 664.0
HKD1_k127_6174915_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 544.0
HKD1_k127_6174915_10 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000003655 87.0
HKD1_k127_6174915_11 Hydrolase Family 16 - - - 0.00000000004786 77.0
HKD1_k127_6174915_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 447.0
HKD1_k127_6174915_3 Bacitracin ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 367.0
HKD1_k127_6174915_4 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 368.0
HKD1_k127_6174915_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 358.0
HKD1_k127_6174915_6 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003367 271.0
HKD1_k127_6174915_7 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000003076 226.0
HKD1_k127_6174915_8 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000004226 231.0
HKD1_k127_6174915_9 PFAM Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000004706 226.0
HKD1_k127_6177872_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1524.0
HKD1_k127_6177872_1 DNA polymerase K02337,K14162 - 2.7.7.7 1.028e-211 694.0
HKD1_k127_6177872_10 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000003701 183.0
HKD1_k127_6177872_11 - - - - 0.00000000000000000000000000000000000000000000001654 175.0
HKD1_k127_6177872_12 - - - - 0.00000000000000000000000000000000000000003404 167.0
HKD1_k127_6177872_2 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 345.0
HKD1_k127_6177872_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 331.0
HKD1_k127_6177872_4 Hsp70 protein K04046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002506 294.0
HKD1_k127_6177872_5 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008277 246.0
HKD1_k127_6177872_6 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000009051 220.0
HKD1_k127_6177872_7 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000006214 210.0
HKD1_k127_6177872_8 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000378 208.0
HKD1_k127_6177872_9 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000007614 195.0
HKD1_k127_6231033_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 2.617e-246 769.0
HKD1_k127_6231033_1 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 556.0
HKD1_k127_6231033_10 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000001 202.0
HKD1_k127_6231033_11 Acetyltransferase - - - 0.000000000000000000000000000000000000000000000000001211 188.0
HKD1_k127_6231033_12 NUDIX domain - - - 0.000000000000000000000000000000000000000000000001328 178.0
HKD1_k127_6231033_13 CYTH domain K05873 - 4.6.1.1 0.000000000000000000000000000000000000000000000001617 180.0
HKD1_k127_6231033_14 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000004351 152.0
HKD1_k127_6231033_15 Domain of unknown function (DUF1905) - - - 0.0000000000000000000000000000000000001453 146.0
HKD1_k127_6231033_16 Acyl-transferase - - - 0.0000000000000000000000000000000676 134.0
HKD1_k127_6231033_17 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000002967 125.0
HKD1_k127_6231033_18 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.000000000000000000000000001703 118.0
HKD1_k127_6231033_19 D-aminopeptidase K16203 - - 0.000000000000000000003089 94.0
HKD1_k127_6231033_20 - - - - 0.00000000000000000004961 96.0
HKD1_k127_6231033_21 ester cyclase - - - 0.000000000000000001785 91.0
HKD1_k127_6231033_3 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 431.0
HKD1_k127_6231033_4 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 369.0
HKD1_k127_6231033_5 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 349.0
HKD1_k127_6231033_6 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 347.0
HKD1_k127_6231033_7 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 334.0
HKD1_k127_6231033_8 PFAM glutamine amidotransferase class-I K07010 - - 0.000000000000000000000000000000000000000000000000000000000000005407 224.0
HKD1_k127_6231033_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000008214 220.0
HKD1_k127_6285070_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1153.0
HKD1_k127_6285070_1 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 3.744e-230 718.0
HKD1_k127_6285070_10 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 318.0
HKD1_k127_6285070_11 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 308.0
HKD1_k127_6285070_12 PFAM diacylglycerol kinase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 297.0
HKD1_k127_6285070_13 phosphatidylinositol kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 288.0
HKD1_k127_6285070_14 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 287.0
HKD1_k127_6285070_15 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003215 285.0
HKD1_k127_6285070_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002967 281.0
HKD1_k127_6285070_17 Protein of unknown function (DUF3090) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004282 256.0
HKD1_k127_6285070_18 NurA - - - 0.000000000000000000000000000000000000000000000000000000000000000000001413 250.0
HKD1_k127_6285070_2 Domain of unknown function DUF87 K06915 - - 5.713e-222 701.0
HKD1_k127_6285070_20 TIGRFAM TIGR02453 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000004091 220.0
HKD1_k127_6285070_21 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000005126 203.0
HKD1_k127_6285070_22 - - - - 0.000000000000000000000000000000000000000000000000000000127 200.0
HKD1_k127_6285070_23 alpha-ribazole phosphatase activity K02226,K15634,K22305 - 3.1.3.3,3.1.3.73,5.4.2.12 0.0000000000000000000000000000000000000000000000000001698 193.0
HKD1_k127_6285070_24 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.00000000000000000000000000000000000000000000000002126 182.0
HKD1_k127_6285070_25 COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases - - - 0.00000000000000000000000000000000000000000000003694 174.0
HKD1_k127_6285070_26 PIN domain - - - 0.0000000000000000000000000000000000000000000004654 171.0
HKD1_k127_6285070_27 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000002391 164.0
HKD1_k127_6285070_28 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000003306 151.0
HKD1_k127_6285070_3 PFAM AAA ATPase central domain protein K07478 - - 6.059e-204 644.0
HKD1_k127_6285070_30 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000008142 118.0
HKD1_k127_6285070_31 Nitroreductase family K19285,K19286 - 1.5.1.38,1.5.1.39 0.000000000000000000000005661 111.0
HKD1_k127_6285070_32 YCII-related domain - - - 0.00000000000000000000008836 101.0
HKD1_k127_6285070_34 PFAM CopG domain protein DNA-binding domain protein - - - 0.0000000000000000008479 89.0
HKD1_k127_6285070_35 - - - - 0.000000000000001298 80.0
HKD1_k127_6285070_36 hydrolase (metallo-beta-lactamase superfamily) K02238 - - 0.00000000000006425 81.0
HKD1_k127_6285070_37 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000003467 74.0
HKD1_k127_6285070_38 Luciferase-like monooxygenase - - - 0.0000000000008661 71.0
HKD1_k127_6285070_39 Hydrogenase maturation protease - - - 0.00000000001311 72.0
HKD1_k127_6285070_4 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 486.0
HKD1_k127_6285070_40 PFAM type IV pilus assembly PilZ - - - 0.0000002608 61.0
HKD1_k127_6285070_41 PFAM Peptidoglycan-binding LysM - - - 0.0000003057 61.0
HKD1_k127_6285070_42 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00001763 53.0
HKD1_k127_6285070_43 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide K02439 - 2.8.1.1 0.00002997 47.0
HKD1_k127_6285070_5 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 494.0
HKD1_k127_6285070_6 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 482.0
HKD1_k127_6285070_7 Helicase conserved C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 482.0
HKD1_k127_6285070_8 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 417.0
HKD1_k127_6285070_9 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009754 358.0
HKD1_k127_6298100_0 Heat shock 70 kDa protein K04043 - - 3.468e-316 977.0
HKD1_k127_6298100_1 PFAM Cytochrome C assembly protein K02198 - - 8.91e-279 872.0
HKD1_k127_6298100_10 - - - - 0.00000000000000000000000000000000000000000000000000001105 200.0
HKD1_k127_6298100_11 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000001156 178.0
HKD1_k127_6298100_12 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000000007315 175.0
HKD1_k127_6298100_13 Ribbon-helix-helix domain - - - 0.0000000000000000000000000000000000002434 149.0
HKD1_k127_6298100_14 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000000000006104 146.0
HKD1_k127_6298100_15 zinc-ribbon domain - - - 0.000000000000000000000000003849 117.0
HKD1_k127_6298100_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 451.0
HKD1_k127_6298100_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 408.0
HKD1_k127_6298100_4 PFAM NMT1 THI5 like domain protein K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 364.0
HKD1_k127_6298100_5 PFAM ABC transporter related K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884 333.0
HKD1_k127_6298100_6 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 317.0
HKD1_k127_6298100_7 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 307.0
HKD1_k127_6298100_8 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 297.0
HKD1_k127_6298100_9 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000000003501 221.0
HKD1_k127_6390084_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 489.0
HKD1_k127_6390084_1 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 465.0
HKD1_k127_6390084_2 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 347.0
HKD1_k127_6390084_3 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 325.0
HKD1_k127_6390084_4 Belongs to the TtcA family K21947 - 2.8.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 289.0
HKD1_k127_6390084_5 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002982 278.0
HKD1_k127_6390084_6 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000003966 157.0
HKD1_k127_6390084_7 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000002942 126.0
HKD1_k127_6390084_8 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000006109 94.0
HKD1_k127_6392136_0 ABC transporter, transmembrane region K06147 - - 2.829e-257 808.0
HKD1_k127_6392136_1 ABC-type multidrug transport system ATPase and permease K06147 - - 2.568e-240 766.0
HKD1_k127_6392136_10 Domain of unknown function (DUF4870) K09940 - - 0.00009202 51.0
HKD1_k127_6392136_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 536.0
HKD1_k127_6392136_3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 387.0
HKD1_k127_6392136_4 PFAM transposase, mutator type K07493 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 292.0
HKD1_k127_6392136_5 Transposase, Mutator family - - - 0.000000000000000000000000000000000000000002276 159.0
HKD1_k127_6392136_6 - - - - 0.0000000000000000000000002378 108.0
HKD1_k127_6392136_7 DNA-binding transcription factor activity - - - 0.0000000000000000000005522 101.0
HKD1_k127_6392136_8 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000002931 79.0
HKD1_k127_6392136_9 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000001203 56.0
HKD1_k127_6425226_0 glucan 1,4-alpha-glucosidase activity - - - 7.82e-211 673.0
HKD1_k127_6425226_1 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 529.0
HKD1_k127_6425226_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 440.0
HKD1_k127_6425226_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 323.0
HKD1_k127_6425226_4 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 308.0
HKD1_k127_6425226_5 Tfp pilus assembly protein tip-associated adhesin K02674,K14379 - 3.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 301.0
HKD1_k127_6425226_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 304.0
HKD1_k127_6425226_7 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000106 238.0
HKD1_k127_6425226_8 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000004675 156.0
HKD1_k127_6425226_9 FR47-like protein - - - 0.00000000000000000000000000000000001242 147.0
HKD1_k127_6463061_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 589.0
HKD1_k127_6463061_1 transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 539.0
HKD1_k127_6463061_10 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 294.0
HKD1_k127_6463061_11 Oxidoreductase molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 288.0
HKD1_k127_6463061_12 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000000000002008 210.0
HKD1_k127_6463061_13 translation initiation inhibitor yjgF family - - - 0.00000000000000000000000000000000000000001206 157.0
HKD1_k127_6463061_14 sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000007136 156.0
HKD1_k127_6463061_15 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000004058 131.0
HKD1_k127_6463061_16 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000001717 121.0
HKD1_k127_6463061_17 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000002094 127.0
HKD1_k127_6463061_18 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.00000000000000000000000000001374 128.0
HKD1_k127_6463061_19 Immune inhibitor A peptidase M6 K09607 - - 0.00000000000000001979 98.0
HKD1_k127_6463061_2 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 383.0
HKD1_k127_6463061_20 Methyltransferase - - - 0.00000000000000002238 87.0
HKD1_k127_6463061_21 - - - - 0.0000000000000000268 85.0
HKD1_k127_6463061_22 - - - - 0.00000000005507 66.0
HKD1_k127_6463061_3 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 375.0
HKD1_k127_6463061_4 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 366.0
HKD1_k127_6463061_5 WD-40 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 397.0
HKD1_k127_6463061_6 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 361.0
HKD1_k127_6463061_7 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 319.0
HKD1_k127_6463061_8 WD-40 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 346.0
HKD1_k127_6463061_9 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 308.0
HKD1_k127_6469602_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 7.23e-313 963.0
HKD1_k127_6469602_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 570.0
HKD1_k127_6469602_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 392.0
HKD1_k127_6469602_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 367.0
HKD1_k127_6469602_4 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 333.0
HKD1_k127_6469602_5 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 318.0
HKD1_k127_6469602_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000001731 201.0
HKD1_k127_6469602_7 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000000000000000000007183 181.0
HKD1_k127_6469602_8 ribosomal protein - - - 0.000000000000000000000000000000000000000007036 157.0
HKD1_k127_6485787_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 6.425e-197 623.0
HKD1_k127_6485787_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006621 282.0
HKD1_k127_6485787_2 CO dehydrogenase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005542 265.0
HKD1_k127_6485787_3 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000674 249.0
HKD1_k127_6485787_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000002461 233.0
HKD1_k127_6485787_5 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.0000000000000000000000000000000000000000000000262 181.0
HKD1_k127_6485787_6 PFAM phospholipase Carboxylesterase K06999 - - 0.0000000000000000000000000000000000008198 147.0
HKD1_k127_6485787_7 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000001617 99.0
HKD1_k127_6485787_8 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000114 57.0
HKD1_k127_6495456_0 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 575.0
HKD1_k127_6495456_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 558.0
HKD1_k127_6495456_10 PFAM binding-protein-dependent transport systems inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 348.0
HKD1_k127_6495456_11 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 343.0
HKD1_k127_6495456_12 PFAM Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 331.0
HKD1_k127_6495456_13 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00571,K00847,K00852 - 2.1.1.72,2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 327.0
HKD1_k127_6495456_14 Rieske 2Fe-2S K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 329.0
HKD1_k127_6495456_15 DNA import into cell involved in transformation K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 289.0
HKD1_k127_6495456_16 response regulator - - - 0.0000000000000000000000000000000000000008737 156.0
HKD1_k127_6495456_17 TIGRFAM parallel beta-helix repeat (two copies) - - - 0.00000000000000000000000000000001356 143.0
HKD1_k127_6495456_18 EamA-like transporter family - - - 0.00000000000000000000000000000006732 136.0
HKD1_k127_6495456_19 Deoxynucleoside kinase - - - 0.000000000000000000000000001617 121.0
HKD1_k127_6495456_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 522.0
HKD1_k127_6495456_20 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 0.000000000000009593 75.0
HKD1_k127_6495456_3 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 499.0
HKD1_k127_6495456_4 PFAM Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 453.0
HKD1_k127_6495456_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 448.0
HKD1_k127_6495456_6 TOBE domain K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 427.0
HKD1_k127_6495456_7 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 419.0
HKD1_k127_6495456_8 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 388.0
HKD1_k127_6495456_9 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 359.0
HKD1_k127_6504869_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 453.0
HKD1_k127_6504869_1 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000001967 206.0
HKD1_k127_6504869_2 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000003236 194.0
HKD1_k127_6504869_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K16216 - 1.1.1.320 0.00000000000000000000000000000000000000000000000000000394 198.0
HKD1_k127_6504869_4 peptidoglycan turnover - - - 0.00000000000000000000000000000000000000000000000000003175 203.0
HKD1_k127_6504869_5 Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.0000000000000000000000000000006257 131.0
HKD1_k127_6504869_6 Dimerisation domain - - - 0.0000000000000000000000003025 118.0
HKD1_k127_6504869_7 SnoaL-like polyketide cyclase - - - 0.0000000000000000000008007 100.0
HKD1_k127_6504869_8 SnoaL-like polyketide cyclase - - - 0.0000000004082 66.0
HKD1_k127_6504869_9 SnoaL-like domain - - - 0.00001732 52.0
HKD1_k127_6530608_0 Family 4 glycosyl hydrolase K01222 - 3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 538.0
HKD1_k127_6530608_1 MarR family - - - 0.0000000000000000000000000000000000000000000006162 170.0
HKD1_k127_6530608_2 Transposase IS200 like - - - 0.0000000000000000000000000000000000001252 149.0
HKD1_k127_6530608_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000001498 151.0
HKD1_k127_6530608_4 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.000000000000000000000000000000001048 133.0
HKD1_k127_6530608_5 Transposase - - - 0.00000003844 55.0
HKD1_k127_6585647_0 carboxylic acid catabolic process K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 429.0
HKD1_k127_6585647_1 transporter K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 430.0
HKD1_k127_6585647_2 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 346.0
HKD1_k127_6585647_3 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000001032 246.0
HKD1_k127_6585647_4 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000001331 211.0
HKD1_k127_6585647_5 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000000000004383 208.0
HKD1_k127_6585647_6 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000002185 179.0
HKD1_k127_6585647_7 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000007964 153.0
HKD1_k127_6624958_0 Participates in both transcription termination and antitermination K02600 - - 3.778e-200 636.0
HKD1_k127_6624958_1 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002111 288.0
HKD1_k127_6624958_2 PFAM Diacylglycerol kinase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005203 244.0
HKD1_k127_6624958_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000002055 184.0
HKD1_k127_6637189_0 PFAM ABC transporter related K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 541.0
HKD1_k127_6637189_1 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 395.0
HKD1_k127_6637189_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000003914 196.0
HKD1_k127_6637189_3 Protein of unknown function (DUF1461) - - - 0.000000000000001284 81.0
HKD1_k127_6640683_0 EamA-like transporter family K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 325.0
HKD1_k127_6640683_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000001502 186.0
HKD1_k127_6640683_2 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.00000000000000000000000000000006044 130.0
HKD1_k127_6640683_3 ABC-type multidrug transport system, ATPase and permease K06147,K06148 - - 0.000001943 49.0
HKD1_k127_6740988_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1133.0
HKD1_k127_6740988_1 PFAM VanW family protein - - - 5.666e-200 640.0
HKD1_k127_6740988_2 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739,K01761 - 2.5.1.48,4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 518.0
HKD1_k127_6740988_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 302.0
HKD1_k127_6740988_4 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002188 287.0
HKD1_k127_6740988_5 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000000006265 108.0
HKD1_k127_6740988_6 phycocyanobilin lyase K02289 - 4.4.1.32 0.0002984 50.0
HKD1_k127_6766676_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000153 256.0
HKD1_k127_6766676_1 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001462 249.0
HKD1_k127_6766676_2 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000004685 185.0
HKD1_k127_6766676_3 PFAM Bacterial regulatory protein, arsR family K21903 - - 0.0000000000000000001167 92.0
HKD1_k127_6766676_4 Peptidase S9 prolyl oligopeptidase active site domain-containing protein - - - 0.00004063 56.0
HKD1_k127_6823400_0 Zn_pept - - - 2.73e-244 765.0
HKD1_k127_6823400_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.721e-210 659.0
HKD1_k127_6823400_10 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 294.0
HKD1_k127_6823400_11 PFAM Stage II sporulation E family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 290.0
HKD1_k127_6823400_12 Lipid kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004506 276.0
HKD1_k127_6823400_13 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000002086 244.0
HKD1_k127_6823400_14 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000009315 205.0
HKD1_k127_6823400_15 CHAD - - - 0.000000000000000000000000000000000000000000000000000000002888 216.0
HKD1_k127_6823400_16 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000002934 172.0
HKD1_k127_6823400_17 aspartic-type endopeptidase activity K02236,K02506,K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000005035 167.0
HKD1_k127_6823400_18 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.000000000000000000000000000000000008749 139.0
HKD1_k127_6823400_19 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000306 137.0
HKD1_k127_6823400_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 507.0
HKD1_k127_6823400_20 sequence-specific DNA binding K07729 - - 0.0000000000000000000000000000001366 129.0
HKD1_k127_6823400_21 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000002764 122.0
HKD1_k127_6823400_22 OsmC-like protein K07397 - - 0.000000000000000000000000007939 115.0
HKD1_k127_6823400_23 Metallo-beta-lactamase superfamily - - - 0.00000695 52.0
HKD1_k127_6823400_3 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 500.0
HKD1_k127_6823400_4 PFAM peptidase M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 491.0
HKD1_k127_6823400_5 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 468.0
HKD1_k127_6823400_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 400.0
HKD1_k127_6823400_7 PFAM TrkA-N domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 355.0
HKD1_k127_6823400_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 346.0
HKD1_k127_6823400_9 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 332.0
HKD1_k127_6877535_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 2.806e-276 868.0
HKD1_k127_6877535_1 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 5.382e-207 651.0
HKD1_k127_6877535_10 PhoQ Sensor K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 417.0
HKD1_k127_6877535_11 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 402.0
HKD1_k127_6877535_12 translation release factor activity K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 388.0
HKD1_k127_6877535_14 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 372.0
HKD1_k127_6877535_15 L-asparaginase II K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 364.0
HKD1_k127_6877535_16 Heat shock protein DnaJ domain protein K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 349.0
HKD1_k127_6877535_17 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 344.0
HKD1_k127_6877535_18 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 342.0
HKD1_k127_6877535_19 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 341.0
HKD1_k127_6877535_2 PFAM fumarate lyase K01679 - 4.2.1.2 5.389e-199 630.0
HKD1_k127_6877535_20 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 323.0
HKD1_k127_6877535_21 FES K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 295.0
HKD1_k127_6877535_22 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 293.0
HKD1_k127_6877535_23 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 289.0
HKD1_k127_6877535_24 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008602 285.0
HKD1_k127_6877535_25 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001586 284.0
HKD1_k127_6877535_26 polysaccharide biosynthetic process K16694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006771 284.0
HKD1_k127_6877535_28 PFAM peptidase M22 glycoprotease K14742 - - 0.000000000000000000000000000000000000000000000000000000000000000001968 233.0
HKD1_k127_6877535_29 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000000000000000001981 207.0
HKD1_k127_6877535_3 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K07303 - 1.3.99.16 8.318e-197 638.0
HKD1_k127_6877535_30 - - - - 0.000000000000000000000000000000000000000000000000000000002433 218.0
HKD1_k127_6877535_31 [2Fe-2S] binding domain K07302,K18029 - 1.17.2.1,1.3.99.16 0.0000000000000000000000000000000000000000000000000001182 190.0
HKD1_k127_6877535_32 DNA-binding transcription factor activity K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000002202 186.0
HKD1_k127_6877535_33 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000001224 165.0
HKD1_k127_6877535_34 PFAM ABC-2 type transporter K09690 - - 0.000000000002916 71.0
HKD1_k127_6877535_35 Endonuclease Exonuclease Phosphatase - - - 0.0000001694 63.0
HKD1_k127_6877535_4 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 494.0
HKD1_k127_6877535_5 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 489.0
HKD1_k127_6877535_6 CoA-transferase family III K07749 GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0047369 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 479.0
HKD1_k127_6877535_7 Short-chain dehydrogenase reductase SDR K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 442.0
HKD1_k127_6877535_8 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 438.0
HKD1_k127_6877535_9 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 408.0
HKD1_k127_7045264_0 ADP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 597.0
HKD1_k127_7045264_1 ADP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 594.0
HKD1_k127_7045264_2 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 475.0
HKD1_k127_7045264_3 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 432.0
HKD1_k127_7045264_4 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K11618 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 290.0
HKD1_k127_7045264_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002303 269.0
HKD1_k127_7045264_6 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000339 154.0
HKD1_k127_7045264_7 - - - - 0.0000000000000000000000000133 113.0
HKD1_k127_7045264_8 YCII-related domain - - - 0.00000003208 59.0
HKD1_k127_7045264_9 Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000009788 63.0
HKD1_k127_7055296_0 GMC oxidoreductase - - - 2.329e-200 636.0
HKD1_k127_7055296_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 457.0
HKD1_k127_7055296_10 acetyltransferase - - - 0.00008068 48.0
HKD1_k127_7055296_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 422.0
HKD1_k127_7055296_3 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 398.0
HKD1_k127_7055296_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 365.0
HKD1_k127_7055296_5 HIT domain K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000861 184.0
HKD1_k127_7055296_6 Divergent PAP2 family K09775 - - 0.000000000000000000000000000000000000000000005897 167.0
HKD1_k127_7055296_7 PhoQ Sensor - - - 0.000000000000000000002005 96.0
HKD1_k127_7055296_8 amidohydrolase - - - 0.00000000000000005398 94.0
HKD1_k127_7055296_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000007709 66.0
HKD1_k127_7072360_0 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.000000000000000000000000000000437 127.0
HKD1_k127_7072360_1 Phosphotransferase enzyme family K17880 - 2.7.1.119 0.000000000006302 77.0
HKD1_k127_7072360_2 ATP binding. It is involved in the biological process described with protein phosphorylation K05124,K05125 GO:0000003,GO:0000902,GO:0000904,GO:0001558,GO:0001763,GO:0001932,GO:0001934,GO:0001952,GO:0002009,GO:0002011,GO:0003416,GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0004714,GO:0004888,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0005886,GO:0005887,GO:0005903,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0006950,GO:0007154,GO:0007155,GO:0007160,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007423,GO:0007565,GO:0007566,GO:0008045,GO:0008150,GO:0008152,GO:0008283,GO:0008284,GO:0008285,GO:0009605,GO:0009611,GO:0009653,GO:0009887,GO:0009888,GO:0009889,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010562,GO:0010604,GO:0010715,GO:0010720,GO:0010762,GO:0010763,GO:0010810,GO:0010975,GO:0010976,GO:0014812,GO:0014909,GO:0015629,GO:0016020,GO:0016021,GO:0016043,GO:0016049,GO:0016301,GO:0016310,GO:0016323,GO:0016324,GO:0016477,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019199,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0022008,GO:0022414,GO:0022610,GO:0022612,GO:0023052,GO:0030030,GO:0030154,GO:0030155,GO:0030182,GO:0030198,GO:0030199,GO:0030278,GO:0030334,GO:0030335,GO:0030424,GO:0030500,GO:0030879,GO:0031099,GO:0031100,GO:0031175,GO:0031214,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0031589,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033674,GO:0035239,GO:0035265,GO:0035295,GO:0035988,GO:0036211,GO:0038023,GO:0038062,GO:0038063,GO:0038064,GO:0038065,GO:0038083,GO:0040007,GO:0040008,GO:0040011,GO:0040012,GO:0040017,GO:0042060,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042330,GO:0042995,GO:0043005,GO:0043062,GO:0043085,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043235,GO:0043412,GO:0043549,GO:0043583,GO:0043588,GO:0043933,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044319,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044703,GO:0044706,GO:0044877,GO:0045177,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045667,GO:0045669,GO:0045778,GO:0045859,GO:0045860,GO:0045937,GO:0046777,GO:0048145,GO:0048146,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048588,GO:0048589,GO:0048666,GO:0048667,GO:0048679,GO:0048680,GO:0048699,GO:0048729,GO:0048731,GO:0048732,GO:0048754,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051090,GO:0051091,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051270,GO:0051272,GO:0051338,GO:0051347,GO:0051674,GO:0051704,GO:0051716,GO:0051960,GO:0051962,GO:0060089,GO:0060255,GO:0060284,GO:0060429,GO:0060443,GO:0060444,GO:0060560,GO:0060562,GO:0060603,GO:0060749,GO:0061138,GO:0061180,GO:0061302,GO:0061377,GO:0061564,GO:0065007,GO:0065009,GO:0070167,GO:0070570,GO:0070572,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0090091,GO:0090504,GO:0090505,GO:0097376,GO:0097435,GO:0097458,GO:0097485,GO:0098590,GO:0098862,GO:0098868,GO:0120025,GO:0120035,GO:0120036,GO:0120039,GO:0140096,GO:1901564,GO:1903034,GO:1903036,GO:1903053,GO:1903055,GO:1903506,GO:1990138,GO:2000026,GO:2000112,GO:2000145,GO:2000147,GO:2001141 2.7.10.1 0.00005044 55.0
HKD1_k127_7084741_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1184.0
HKD1_k127_7084741_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.19e-315 973.0
HKD1_k127_7084741_10 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 402.0
HKD1_k127_7084741_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 392.0
HKD1_k127_7084741_12 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 379.0
HKD1_k127_7084741_13 Periplasmic binding protein-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 377.0
HKD1_k127_7084741_14 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 365.0
HKD1_k127_7084741_15 Alcohol dehydrogenase GroES-like domain K00004,K00008,K00098 - 1.1.1.14,1.1.1.264,1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 352.0
HKD1_k127_7084741_16 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 335.0
HKD1_k127_7084741_17 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 321.0
HKD1_k127_7084741_18 Class II Aldolase and Adducin N-terminal domain K01628,K03077 - 4.1.2.17,5.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 302.0
HKD1_k127_7084741_19 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002134 285.0
HKD1_k127_7084741_2 FGGY family of carbohydrate kinases, N-terminal domain K00853 - 2.7.1.16 2.7e-285 884.0
HKD1_k127_7084741_20 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003791 280.0
HKD1_k127_7084741_21 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001833 264.0
HKD1_k127_7084741_22 MFS/sugar transport protein K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004261 275.0
HKD1_k127_7084741_23 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000003505 242.0
HKD1_k127_7084741_24 PFAM RNA binding S1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000004342 212.0
HKD1_k127_7084741_25 Redoxin K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000008682 192.0
HKD1_k127_7084741_26 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.00000000000000000000000000000000000000000469 173.0
HKD1_k127_7084741_27 - - - - 0.00000000000000000000000000000000000000002587 156.0
HKD1_k127_7084741_28 cheY-homologous receiver domain K07668 - - 0.00000000000000000000000000000000000000002843 156.0
HKD1_k127_7084741_3 L-arabinose isomerase activity K01804 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 1.289e-233 731.0
HKD1_k127_7084741_30 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000000000000004541 121.0
HKD1_k127_7084741_31 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000007632 116.0
HKD1_k127_7084741_32 Transglutaminase-like superfamily - - - 0.00000000000000000000005834 110.0
HKD1_k127_7084741_34 response regulator receiver - - - 0.0002559 46.0
HKD1_k127_7084741_4 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K03336 - 3.7.1.22 1.107e-198 636.0
HKD1_k127_7084741_5 Pyruvate formate lyase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 580.0
HKD1_k127_7084741_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 536.0
HKD1_k127_7084741_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 487.0
HKD1_k127_7084741_8 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 430.0
HKD1_k127_7084741_9 Metallopeptidase family M24 K18829 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 414.0
HKD1_k127_7096001_0 PFAM Glycoside hydrolase family 42 domain protein K12308 - 3.2.1.23 8.843e-265 831.0
HKD1_k127_7096001_1 Streptomycin adenylyltransferase K05593 - - 0.00000000000000000000000000000000000000000000000000000000000000001005 233.0
HKD1_k127_710569_0 formate C-acetyltransferase glycine radical - - - 0.0 1210.0
HKD1_k127_710569_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 365.0
HKD1_k127_710569_2 Pyridoxamine 5'-phosphate oxidase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005365 272.0
HKD1_k127_710569_3 - - - - 0.000000000000000000000000003111 127.0
HKD1_k127_7112468_0 Radical SAM K06871 - - 7.204e-200 630.0
HKD1_k127_7112468_1 COG0659 Sulfate permease and related transporters (MFS superfamily K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006248 261.0
HKD1_k127_7112468_2 AI-2E family transporter - - - 0.00000000000003436 84.0
HKD1_k127_7117064_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 3.177e-217 700.0
HKD1_k127_7117064_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 451.0
HKD1_k127_7117064_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 421.0
HKD1_k127_7117064_3 PFAM oxidoreductase, molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009853 354.0
HKD1_k127_7117064_4 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 321.0
HKD1_k127_7117064_6 amino acid activation for nonribosomal peptide biosynthetic process K14379 - 3.1.3.2 0.0000000004044 68.0
HKD1_k127_7126124_0 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 530.0
HKD1_k127_7126124_1 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 435.0
HKD1_k127_7126124_2 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 341.0
HKD1_k127_7126124_3 Methyltransferase domain K06983 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 301.0
HKD1_k127_7126124_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.000000000000000000000000000000000000000000000000000000000517 210.0
HKD1_k127_7126124_5 PFAM Pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000003167 201.0
HKD1_k127_7126124_6 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000000000003259 165.0
HKD1_k127_7126124_7 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025,K20866 - 3.1.3.10 0.00000000000000000000005838 106.0
HKD1_k127_7126124_8 4 iron, 4 sulfur cluster binding K00176,K00528,K03737,K20449 - 1.18.1.2,1.19.1.1,1.2.7.1,1.2.7.3,1.3.7.1 0.00000000000000000002215 93.0
HKD1_k127_7126124_9 Prenyltransferase and squalene oxidase repeat - - - 0.0000005584 60.0
HKD1_k127_7300542_0 Selenocysteine-specific translation elongation factor K03833 - - 3.718e-243 766.0
HKD1_k127_7300542_1 Amidohydrolase family K01464,K01466 - 3.5.2.2,3.5.2.5 3.497e-224 703.0
HKD1_k127_7300542_10 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000003944 209.0
HKD1_k127_7300542_12 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.00000000000000000000000000000000000000000000000004931 183.0
HKD1_k127_7300542_13 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000001223 177.0
HKD1_k127_7300542_14 acetyltransferase K03826 - - 0.0000000000000000000000000000597 121.0
HKD1_k127_7300542_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000004984 117.0
HKD1_k127_7300542_17 Putative zinc-finger - - - 0.000000000000000000002641 96.0
HKD1_k127_7300542_18 Acetyltransferase (GNAT) family - - - 0.00000000000000000001169 102.0
HKD1_k127_7300542_19 response regulator K03413,K07719 - - 0.000000000000001939 79.0
HKD1_k127_7300542_2 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 588.0
HKD1_k127_7300542_20 TadE-like protein - - - 0.0000000003799 67.0
HKD1_k127_7300542_21 PFAM TadE family protein - - - 0.000002056 60.0
HKD1_k127_7300542_22 TadE-like protein - - - 0.000007813 55.0
HKD1_k127_7300542_23 - - - - 0.0005997 43.0
HKD1_k127_7300542_24 Tfp pilus assembly protein FimV - - - 0.0006451 50.0
HKD1_k127_7300542_3 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 576.0
HKD1_k127_7300542_4 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 577.0
HKD1_k127_7300542_5 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 427.0
HKD1_k127_7300542_6 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 342.0
HKD1_k127_7300542_7 Proton-conducting membrane transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 344.0
HKD1_k127_7300542_8 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003415 258.0
HKD1_k127_7300542_9 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000257 224.0
HKD1_k127_7325563_0 PFAM ABC-1 domain protein K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 463.0
HKD1_k127_7325563_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000004995 130.0
HKD1_k127_7325563_2 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0006972 44.0
HKD1_k127_7336095_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007939 302.0
HKD1_k127_7336095_1 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000002157 226.0
HKD1_k127_7336095_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000006459 226.0
HKD1_k127_7336095_3 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000002425 206.0
HKD1_k127_7336095_5 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000000006298 171.0
HKD1_k127_7336095_6 Carotenoid biosynthesis protein K22502 - 5.5.1.19 0.000000000000000000000000000000000000005781 156.0
HKD1_k127_7336095_8 Domain of unknown function (DUF4203) - - - 0.0000000000000001634 86.0
HKD1_k127_7336095_9 DNA excision K02806 - - 0.000002584 54.0
HKD1_k127_73474_0 Oligopeptidase F K08602 - - 1.993e-218 694.0
HKD1_k127_73474_1 cellulose binding - - - 1.075e-203 638.0
HKD1_k127_73474_10 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001521 254.0
HKD1_k127_73474_11 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000006576 222.0
HKD1_k127_73474_12 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000001676 207.0
HKD1_k127_73474_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000001811 200.0
HKD1_k127_73474_14 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000005393 193.0
HKD1_k127_73474_15 Dna alkylation repair - - - 0.000000000000000000000000000000000000000000000000006447 188.0
HKD1_k127_73474_16 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000543 176.0
HKD1_k127_73474_17 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000005169 166.0
HKD1_k127_73474_18 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000005491 170.0
HKD1_k127_73474_19 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000007359 164.0
HKD1_k127_73474_2 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 474.0
HKD1_k127_73474_20 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000001173 146.0
HKD1_k127_73474_22 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000002259 123.0
HKD1_k127_73474_23 CoA binding domain K09181 - - 0.000000000000000000000000008666 116.0
HKD1_k127_73474_24 Transposase IS200 like - - - 0.00000000000000000000001163 103.0
HKD1_k127_73474_25 Leucine carboxyl methyltransferase - - - 0.000000000000000000001049 105.0
HKD1_k127_73474_26 Protein of unknown function (DUF1706) - - - 0.00000000000000000004184 96.0
HKD1_k127_73474_27 PFAM Transposase IS200 like - - - 0.0000000000000048 78.0
HKD1_k127_73474_28 transcriptional regulator, LuxR family K08282 - 2.7.11.1 0.00000000000252 81.0
HKD1_k127_73474_29 Glyoxalase - - - 0.000007459 53.0
HKD1_k127_73474_3 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000873 467.0
HKD1_k127_73474_4 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 427.0
HKD1_k127_73474_5 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 402.0
HKD1_k127_73474_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 362.0
HKD1_k127_73474_7 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 330.0
HKD1_k127_73474_8 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009114 249.0
HKD1_k127_73474_9 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000002276 256.0
HKD1_k127_7350925_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000587 239.0
HKD1_k127_7350925_1 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000006727 239.0
HKD1_k127_7350925_2 PFAM Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000745 202.0
HKD1_k127_7350925_3 cyclic nucleotide binding K10914 - - 0.000000000000000000000000000000001088 135.0
HKD1_k127_7350925_4 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000000000000000000002852 128.0
HKD1_k127_7350925_5 iron-sulfur cluster assembly - - - 0.00000000000000000000000000133 113.0
HKD1_k127_7350925_6 PFAM Transposase IS200 like - - - 0.0000000000000000007206 89.0
HKD1_k127_7350925_7 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.0000000000000002448 80.0
HKD1_k127_7350925_8 - - - - 0.000000000006677 70.0
HKD1_k127_7350925_9 N-terminal 7TM region of histidine kinase - - - 0.00000003314 66.0
HKD1_k127_7360448_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 2.819e-272 852.0
HKD1_k127_7360448_1 Serine threonine protein kinase K12132 - 2.7.11.1 4.919e-269 841.0
HKD1_k127_7360448_10 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 360.0
HKD1_k127_7360448_11 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 357.0
HKD1_k127_7360448_12 PFAM ABC transporter related K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 337.0
HKD1_k127_7360448_13 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 334.0
HKD1_k127_7360448_14 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 322.0
HKD1_k127_7360448_15 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 323.0
HKD1_k127_7360448_16 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 298.0
HKD1_k127_7360448_17 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000002106 272.0
HKD1_k127_7360448_18 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000007209 220.0
HKD1_k127_7360448_19 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000000000000000000000006138 179.0
HKD1_k127_7360448_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 2.785e-242 756.0
HKD1_k127_7360448_20 Domain of unknown function (DUF4870) K09940 - - 0.000000000000000000000000000000000000000000001992 168.0
HKD1_k127_7360448_21 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000001698 171.0
HKD1_k127_7360448_22 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000002284 162.0
HKD1_k127_7360448_23 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000003411 158.0
HKD1_k127_7360448_24 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000004134 152.0
HKD1_k127_7360448_25 Domain of unknown function (DUF4870) - - - 0.00000000000000000000000000118 116.0
HKD1_k127_7360448_26 - - - - 0.000000000000000000000005805 103.0
HKD1_k127_7360448_3 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 2.62e-233 734.0
HKD1_k127_7360448_4 protein kinase activity - - - 3.492e-220 718.0
HKD1_k127_7360448_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 517.0
HKD1_k127_7360448_6 extracellular polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 469.0
HKD1_k127_7360448_7 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 455.0
HKD1_k127_7360448_8 PFAM molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 382.0
HKD1_k127_7360448_9 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 365.0
HKD1_k127_7362756_0 Dehydrogenase E1 component K00615 - 2.2.1.1 3.519e-313 979.0
HKD1_k127_7362756_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 5.062e-227 721.0
HKD1_k127_7362756_2 PFAM PDZ DHR GLGF domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004404 268.0
HKD1_k127_7362756_3 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000003647 185.0
HKD1_k127_7362756_4 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000005367 107.0
HKD1_k127_7404715_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 2.793e-257 801.0
HKD1_k127_7404715_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 561.0
HKD1_k127_7404715_10 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 328.0
HKD1_k127_7404715_11 L-lactate permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008731 326.0
HKD1_k127_7404715_12 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 301.0
HKD1_k127_7404715_13 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003623 276.0
HKD1_k127_7404715_14 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003148 266.0
HKD1_k127_7404715_15 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009067 253.0
HKD1_k127_7404715_16 PFAM secretion protein HlyD family protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005582 258.0
HKD1_k127_7404715_17 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000428 230.0
HKD1_k127_7404715_18 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000001043 225.0
HKD1_k127_7404715_19 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.0000000000000000000000000000000000000000000000000000000000003865 225.0
HKD1_k127_7404715_2 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 478.0
HKD1_k127_7404715_20 Methyltransferase type - - - 0.00000000000000000000000000000000000000000000000000000000001756 214.0
HKD1_k127_7404715_21 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000000000000000000008521 180.0
HKD1_k127_7404715_22 cellulose binding - - - 0.00000000000000000000000000000000000000000001432 184.0
HKD1_k127_7404715_23 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000007351 154.0
HKD1_k127_7404715_24 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000035 141.0
HKD1_k127_7404715_25 dnaJ homolog subfamily C member K19373 - - 0.0000000000000000003518 93.0
HKD1_k127_7404715_27 SnoaL-like polyketide cyclase - - - 0.000000000000000002437 90.0
HKD1_k127_7404715_28 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000001895 80.0
HKD1_k127_7404715_29 Protein of unknown function (DUF2892) - - - 0.000000000000287 73.0
HKD1_k127_7404715_3 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 442.0
HKD1_k127_7404715_30 Redoxin - - - 0.00000000003825 64.0
HKD1_k127_7404715_31 EamA-like transporter family - - - 0.00000000009135 65.0
HKD1_k127_7404715_32 cellulose binding - - - 0.0000000001703 74.0
HKD1_k127_7404715_33 - - - - 0.000000001101 65.0
HKD1_k127_7404715_34 Zinc ribbon domain - - - 0.000000002025 60.0
HKD1_k127_7404715_35 phosphatase K04459,K14165 - 3.1.3.16,3.1.3.48 0.00000001639 63.0
HKD1_k127_7404715_36 domain, Protein K08961 - 4.2.2.20,4.2.2.21 0.00000008729 63.0
HKD1_k127_7404715_37 SMART Animal peptidoglycan recognition protein PGRP - - - 0.000000523 63.0
HKD1_k127_7404715_38 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.0000006117 58.0
HKD1_k127_7404715_4 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 421.0
HKD1_k127_7404715_40 bacterial-type flagellum-dependent cell motility - - - 0.00002103 55.0
HKD1_k127_7404715_41 - - - - 0.0008002 42.0
HKD1_k127_7404715_5 PFAM Radical SAM domain protein K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 398.0
HKD1_k127_7404715_6 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 418.0
HKD1_k127_7404715_7 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 362.0
HKD1_k127_7404715_8 galactokinase activity K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 348.0
HKD1_k127_7404715_9 ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 344.0
HKD1_k127_7418128_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1152.0
HKD1_k127_7418128_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 539.0
HKD1_k127_7418128_10 response regulator, receiver - - - 0.0000000000000103 79.0
HKD1_k127_7418128_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 462.0
HKD1_k127_7418128_3 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 410.0
HKD1_k127_7418128_4 Integral membrane sensor signal transduction histidine kinase K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 379.0
HKD1_k127_7418128_5 PFAM deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 339.0
HKD1_k127_7418128_6 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 325.0
HKD1_k127_7418128_7 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006173 278.0
HKD1_k127_7418128_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000005203 252.0
HKD1_k127_7418128_9 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000000000000003054 144.0
HKD1_k127_7443711_0 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 8.255e-310 964.0
HKD1_k127_7443711_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 3.378e-221 696.0
HKD1_k127_7443711_10 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002655 246.0
HKD1_k127_7443711_11 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000006396 221.0
HKD1_k127_7443711_12 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000001505 158.0
HKD1_k127_7443711_13 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000001507 147.0
HKD1_k127_7443711_14 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000008 141.0
HKD1_k127_7443711_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000001801 135.0
HKD1_k127_7443711_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.000000000000000000000000000000003878 131.0
HKD1_k127_7443711_17 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000004013 72.0
HKD1_k127_7443711_2 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 5.228e-202 641.0
HKD1_k127_7443711_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 3.711e-198 628.0
HKD1_k127_7443711_4 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 503.0
HKD1_k127_7443711_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 476.0
HKD1_k127_7443711_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 447.0
HKD1_k127_7443711_7 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 364.0
HKD1_k127_7443711_8 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 319.0
HKD1_k127_7443711_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002671 259.0
HKD1_k127_7453384_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 3.33e-217 706.0
HKD1_k127_7453384_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.821e-214 671.0
HKD1_k127_7453384_10 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 334.0
HKD1_k127_7453384_11 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 315.0
HKD1_k127_7453384_12 Belongs to the peptidase S51 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 319.0
HKD1_k127_7453384_13 sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003124 257.0
HKD1_k127_7453384_14 PFAM Translin K07477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004481 246.0
HKD1_k127_7453384_15 DNA methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000298 224.0
HKD1_k127_7453384_16 - - - - 0.00000000000000000000000000000000000000000000000000000000001403 210.0
HKD1_k127_7453384_17 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000000000000000000004509 207.0
HKD1_k127_7453384_18 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000000000000000000000000002334 185.0
HKD1_k127_7453384_19 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000001272 175.0
HKD1_k127_7453384_2 PFAM glycosyl transferase, family 51 - - - 3.573e-202 663.0
HKD1_k127_7453384_20 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000002571 166.0
HKD1_k127_7453384_21 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000000000000000001285 161.0
HKD1_k127_7453384_22 - - - - 0.000000000000000000000000000000000000000003183 165.0
HKD1_k127_7453384_23 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000004738 160.0
HKD1_k127_7453384_24 TIGRFAM glutaredoxin-like domain protein - - - 0.0000000000000000000000000000000000000001138 154.0
HKD1_k127_7453384_25 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000000000000000000000000000009133 131.0
HKD1_k127_7453384_26 TIGRFAM Glutaredoxin-like domain protein - - - 0.00000000000000000003827 91.0
HKD1_k127_7453384_28 Protein of unknown function (DUF3467) - - - 0.000000000000002233 80.0
HKD1_k127_7453384_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 589.0
HKD1_k127_7453384_30 Type ii and iii secretion system protein - - - 0.00000003044 65.0
HKD1_k127_7453384_31 AntiSigma factor - - - 0.00006425 55.0
HKD1_k127_7453384_32 TIGRFAM conserved repeat domain - - - 0.0001707 53.0
HKD1_k127_7453384_4 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 580.0
HKD1_k127_7453384_5 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 492.0
HKD1_k127_7453384_6 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 498.0
HKD1_k127_7453384_8 2-hydroxy-3-oxopropionate reductase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 350.0
HKD1_k127_7453384_9 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 350.0
HKD1_k127_7468903_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1073.0
HKD1_k127_7468903_1 Protein of unknown function (DUF1116) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 561.0
HKD1_k127_7468903_2 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 526.0
HKD1_k127_7468903_3 CoA-ligase K01902,K02381 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009361,GO:0032991,GO:0042709,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:1902494 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 469.0
HKD1_k127_7468903_4 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 314.0
HKD1_k127_7468903_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000271 280.0
HKD1_k127_7468903_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000549 246.0
HKD1_k127_7468903_7 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000005407 235.0
HKD1_k127_7468903_8 DNA alkylation repair enzyme - - - 0.0000000001954 71.0
HKD1_k127_7546376_0 PFAM extracellular solute-binding protein family 1 K02027,K10188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 600.0
HKD1_k127_7546376_1 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 540.0
HKD1_k127_7546376_10 Protein of unknown function (DUF1385) K09153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 358.0
HKD1_k127_7546376_11 SIS domain K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 352.0
HKD1_k127_7546376_12 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 340.0
HKD1_k127_7546376_13 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 329.0
HKD1_k127_7546376_14 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 321.0
HKD1_k127_7546376_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 304.0
HKD1_k127_7546376_16 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 299.0
HKD1_k127_7546376_17 DeoR C terminal sensor domain K02081 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003294 284.0
HKD1_k127_7546376_18 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002452 283.0
HKD1_k127_7546376_19 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002886 297.0
HKD1_k127_7546376_2 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 523.0
HKD1_k127_7546376_20 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001756 270.0
HKD1_k127_7546376_21 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000003942 259.0
HKD1_k127_7546376_22 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000002062 254.0
HKD1_k127_7546376_23 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.000000000000000000000000000000000000000000000000000000000000005436 227.0
HKD1_k127_7546376_24 FAD binding domain in molybdopterin dehydrogenase K03519,K12529 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000772 205.0
HKD1_k127_7546376_25 ferredoxin-NADP+ reductase activity - - - 0.0000000000000000000000000000000000000000000000000000001097 204.0
HKD1_k127_7546376_26 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000001252 196.0
HKD1_k127_7546376_27 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.0000000000000000000000000000000000000000000000004599 182.0
HKD1_k127_7546376_28 Thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000004291 178.0
HKD1_k127_7546376_29 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000001155 175.0
HKD1_k127_7546376_3 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 498.0
HKD1_k127_7546376_30 Cache domain - - - 0.000000000000000000000000000000000000000000007061 188.0
HKD1_k127_7546376_31 Protein of unknown function (DUF1361) - - - 0.0000000000000000000000000000000000000002408 158.0
HKD1_k127_7546376_32 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000003232 141.0
HKD1_k127_7546376_33 protein conserved in bacteria - - - 0.0000000000000000000000000000001748 129.0
HKD1_k127_7546376_34 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000002059 123.0
HKD1_k127_7546376_35 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000001383 103.0
HKD1_k127_7546376_36 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000002282 93.0
HKD1_k127_7546376_37 4Fe-4S binding domain protein - - - 0.000000000002918 70.0
HKD1_k127_7546376_38 thiamine diphosphate biosynthetic process K03154 - - 0.0000005975 53.0
HKD1_k127_7546376_39 domain, Protein - - - 0.000003181 59.0
HKD1_k127_7546376_4 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 462.0
HKD1_k127_7546376_5 fructose 1,6-bisphosphate 1-phosphatase activity K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 464.0
HKD1_k127_7546376_6 Tagatose 6 phosphate kinase K16371 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 460.0
HKD1_k127_7546376_7 DNA methylase K00571,K13581 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005479 437.0
HKD1_k127_7546376_8 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 403.0
HKD1_k127_7546376_9 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 402.0
HKD1_k127_7553139_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 3.215e-250 802.0
HKD1_k127_7553139_1 His Kinase A (phosphoacceptor) domain - - - 5.807e-221 696.0
HKD1_k127_7553139_10 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002635 254.0
HKD1_k127_7553139_11 PFAM Transketolase central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000002044 222.0
HKD1_k127_7553139_12 GHMP kinases C terminal K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000004257 219.0
HKD1_k127_7553139_13 Prolyl-tRNA synthetase K03976 - - 0.0000000000000000000000000000000000000000000000000000007645 196.0
HKD1_k127_7553139_14 Acyl CoA acetate 3-ketoacid CoA K01040 - 2.8.3.12 0.00000000000000000000000000000000000000003968 164.0
HKD1_k127_7553139_16 PFAM extracellular solute-binding protein family 1 K02040 - - 0.00000000000003974 83.0
HKD1_k127_7553139_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 600.0
HKD1_k127_7553139_3 Serine threonine protein kinase K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 471.0
HKD1_k127_7553139_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 446.0
HKD1_k127_7553139_5 CpXC protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 402.0
HKD1_k127_7553139_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 322.0
HKD1_k127_7553139_7 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 316.0
HKD1_k127_7553139_8 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 291.0
HKD1_k127_7553139_9 phosphoesterase RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004655 267.0
HKD1_k127_7557391_0 DNA helicase - - - 3.617e-207 661.0
HKD1_k127_7557391_1 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 3.091e-206 645.0
HKD1_k127_7557391_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 362.0
HKD1_k127_7557391_3 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 321.0
HKD1_k127_7557391_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000000009631 202.0
HKD1_k127_7557391_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000004241 196.0
HKD1_k127_7557391_6 - - - - 0.00000000000131 75.0
HKD1_k127_7557391_7 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0001663 48.0
HKD1_k127_7567216_0 UDP-N-acetylglucosamine 2-epimerase activity - - - 6.141e-194 619.0
HKD1_k127_7567216_1 3-deoxy-manno-octulosonate-8-phosphatase activity K00983,K03270 - 2.7.7.43,3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 531.0
HKD1_k127_7567216_10 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000005979 227.0
HKD1_k127_7567216_11 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000004379 208.0
HKD1_k127_7567216_12 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000008655 197.0
HKD1_k127_7567216_13 bis(5'-adenosyl)-triphosphatase activity - - - 0.0000000000000000000000000000000000002077 145.0
HKD1_k127_7567216_14 Methyltransferase domain - - - 0.000000000000000000000000000000003018 138.0
HKD1_k127_7567216_15 Methyltransferase domain - - - 0.0000000000000002 89.0
HKD1_k127_7567216_16 Psort location CytoplasmicMembrane, score - - - 0.0000000007284 72.0
HKD1_k127_7567216_17 glycosyl transferase family 2 - - - 0.000000006016 66.0
HKD1_k127_7567216_2 SAF K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 499.0
HKD1_k127_7567216_3 NeuB family K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 448.0
HKD1_k127_7567216_4 inositol 2-dehydrogenase activity K18431 - 2.7.7.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 422.0
HKD1_k127_7567216_5 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 375.0
HKD1_k127_7567216_6 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 372.0
HKD1_k127_7567216_7 Glycosyl transferase, family 2 K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 347.0
HKD1_k127_7567216_8 PFAM NAD-dependent epimerase dehydratase K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 319.0
HKD1_k127_7567216_9 Cytidylyltransferase K07257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003601 251.0
HKD1_k127_7609401_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1221.0
HKD1_k127_7609401_1 TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 4.702e-273 853.0
HKD1_k127_7609401_10 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 301.0
HKD1_k127_7609401_11 Hep Hag repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 317.0
HKD1_k127_7609401_12 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001872 289.0
HKD1_k127_7609401_13 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001395 271.0
HKD1_k127_7609401_14 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000002071 260.0
HKD1_k127_7609401_15 Ser Thr phosphatase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001071 260.0
HKD1_k127_7609401_16 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000007795 226.0
HKD1_k127_7609401_17 lysyltransferase activity K07027,K14205 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 0.000000000000000000000000000000000000000000000000000000000003001 222.0
HKD1_k127_7609401_18 4Fe-4S dicluster domain K00196 - - 0.000000000000000000000000000000000000000000000000000000000004396 214.0
HKD1_k127_7609401_19 - - - - 0.000000000000000000000000000000000000000000000000000000000006321 222.0
HKD1_k127_7609401_2 ADP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 610.0
HKD1_k127_7609401_20 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000372 228.0
HKD1_k127_7609401_21 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000708 213.0
HKD1_k127_7609401_22 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000001574 201.0
HKD1_k127_7609401_23 PFAM Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.00000000000000000000000000000000000000000000000003336 182.0
HKD1_k127_7609401_24 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000378 178.0
HKD1_k127_7609401_25 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000133 178.0
HKD1_k127_7609401_26 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000009478 167.0
HKD1_k127_7609401_27 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000003728 158.0
HKD1_k127_7609401_28 Butirosin biosynthesis protein H, N-terminal - - - 0.00000000000000000000000000000000000001348 158.0
HKD1_k127_7609401_29 histidine kinase A domain protein domain protein - - - 0.00000000000000000000000000000000001827 158.0
HKD1_k127_7609401_3 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 590.0
HKD1_k127_7609401_30 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000002015 139.0
HKD1_k127_7609401_31 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000000000000000002705 138.0
HKD1_k127_7609401_32 acetyltransferase - - - 0.0000000000000000000000000000000002519 144.0
HKD1_k127_7609401_33 Hemerythrin HHE cation binding - - - 0.000000000000000000000000000000004169 136.0
HKD1_k127_7609401_34 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000003595 145.0
HKD1_k127_7609401_35 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000003833 135.0
HKD1_k127_7609401_36 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000001628 118.0
HKD1_k127_7609401_37 protein conserved in bacteria - - - 0.0000000000000000000000000005512 117.0
HKD1_k127_7609401_38 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000001612 119.0
HKD1_k127_7609401_39 Fungalysin metallopeptidase (M36) - - - 0.000000000000000000000000005147 129.0
HKD1_k127_7609401_4 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 506.0
HKD1_k127_7609401_40 Wd40 repeat-containing protein - - - 0.0000000000000000000000007289 117.0
HKD1_k127_7609401_41 PFAM Acetoacetate decarboxylase - - - 0.0000000000000000000004638 106.0
HKD1_k127_7609401_42 GIY-YIG catalytic domain K07461 - - 0.000000000000000000009795 94.0
HKD1_k127_7609401_43 conserved repeat domain protein - - - 0.00000000000000000008379 106.0
HKD1_k127_7609401_44 Leucine carboxyl methyltransferase - - - 0.0000000000000000002554 91.0
HKD1_k127_7609401_45 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000005369 94.0
HKD1_k127_7609401_46 cellulose binding - - - 0.0000000000000002971 93.0
HKD1_k127_7609401_48 Acyltransferase K00655 - 2.3.1.51 0.00000000000000194 85.0
HKD1_k127_7609401_49 Ergosterol biosynthesis ERG4/ERG24 family - - - 0.00000000001637 73.0
HKD1_k127_7609401_5 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 459.0
HKD1_k127_7609401_52 AI-2E family transporter - - - 0.000000004713 68.0
HKD1_k127_7609401_54 zinc ion binding K00504,K16276,K18200 GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0006464,GO:0006508,GO:0006511,GO:0006605,GO:0006626,GO:0006807,GO:0006810,GO:0006839,GO:0006873,GO:0006875,GO:0006879,GO:0006886,GO:0006950,GO:0006996,GO:0007005,GO:0007154,GO:0008104,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009057,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010498,GO:0015031,GO:0015833,GO:0016043,GO:0016567,GO:0016740,GO:0017038,GO:0019538,GO:0019725,GO:0019787,GO:0019941,GO:0030003,GO:0030163,GO:0031667,GO:0031668,GO:0031669,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032446,GO:0032501,GO:0033036,GO:0033365,GO:0033554,GO:0034613,GO:0036211,GO:0042592,GO:0042594,GO:0042886,GO:0043161,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044743,GO:0045041,GO:0045184,GO:0046872,GO:0046907,GO:0046914,GO:0046916,GO:0048871,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051603,GO:0051641,GO:0051649,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060586,GO:0061630,GO:0061659,GO:0065002,GO:0065007,GO:0065008,GO:0070013,GO:0070585,GO:0070647,GO:0070727,GO:0071496,GO:0071702,GO:0071704,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072655,GO:0098771,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1990542 1.14.17.3,4.3.2.5 0.000000215 60.0
HKD1_k127_7609401_55 - - - - 0.000001383 59.0
HKD1_k127_7609401_56 Belongs to the peptidase M50B family - - - 0.000005759 57.0
HKD1_k127_7609401_57 nUDIX hydrolase K01515 - 3.6.1.13 0.0002769 49.0
HKD1_k127_7609401_6 WD-40 repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 459.0
HKD1_k127_7609401_7 SERine Proteinase INhibitors K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 388.0
HKD1_k127_7609401_8 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 353.0
HKD1_k127_7609401_9 filamentation induced by cAMP protein Fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 346.0
HKD1_k127_7727155_0 penicillin amidase K01434 - 3.5.1.11 1.538e-320 1002.0
HKD1_k127_7727155_1 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 514.0
HKD1_k127_7727155_10 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000003729 155.0
HKD1_k127_7727155_11 SMS protein - - - 0.000000000000000000000000000000325 132.0
HKD1_k127_7727155_12 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000005242 126.0
HKD1_k127_7727155_13 - - - - 0.000000000000000000000000000005871 129.0
HKD1_k127_7727155_14 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000006433 93.0
HKD1_k127_7727155_15 Phospholipase_D-nuclease N-terminal - - - 0.0000000000005406 72.0
HKD1_k127_7727155_2 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 482.0
HKD1_k127_7727155_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 469.0
HKD1_k127_7727155_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 373.0
HKD1_k127_7727155_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 346.0
HKD1_k127_7727155_6 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 300.0
HKD1_k127_7727155_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006039 273.0
HKD1_k127_7727155_8 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000198 263.0
HKD1_k127_7727155_9 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004371 248.0
HKD1_k127_7744952_0 PFAM ABC transporter K06020 - 3.6.3.25 3.148e-277 863.0
HKD1_k127_7744952_1 peptidase - - - 1.75e-258 810.0
HKD1_k127_7744952_10 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 339.0
HKD1_k127_7744952_11 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 307.0
HKD1_k127_7744952_12 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000911 308.0
HKD1_k127_7744952_13 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 293.0
HKD1_k127_7744952_14 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000009673 252.0
HKD1_k127_7744952_15 Ribosomal protein L11 methyltransferase (PrmA) K00564 - 2.1.1.172 0.000000000000000000000000000000000000000000000000000000000000000000004415 249.0
HKD1_k127_7744952_16 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000001506 202.0
HKD1_k127_7744952_17 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000002064 193.0
HKD1_k127_7744952_18 - - - - 0.000000000000000000000000000000000000000000000009946 179.0
HKD1_k127_7744952_19 - - - - 0.0000000000000000000000000000000000000000000004435 172.0
HKD1_k127_7744952_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 5.9e-246 781.0
HKD1_k127_7744952_20 NUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.00000000000000000000000000000000000000004376 159.0
HKD1_k127_7744952_21 DNA helicase - - - 0.0000000000000000000000000000000000000003716 151.0
HKD1_k127_7744952_22 COG1278 Cold shock proteins K03704 - - 0.0000000000000000000000000003927 114.0
HKD1_k127_7744952_23 SCP-2 sterol transfer family - - - 0.00000000000000000000000008463 111.0
HKD1_k127_7744952_3 DHH family K07462 - - 9.09e-204 659.0
HKD1_k127_7744952_4 Molecular chaperone. Has ATPase activity K04079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 594.0
HKD1_k127_7744952_5 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 505.0
HKD1_k127_7744952_6 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 485.0
HKD1_k127_7744952_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 455.0
HKD1_k127_7744952_8 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 434.0
HKD1_k127_7744952_9 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 393.0
HKD1_k127_7757702_0 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 565.0
HKD1_k127_7757702_1 PFAM Methicillin resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 394.0
HKD1_k127_7757702_2 1-aminocyclopropane-1-carboxylate deaminase K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 371.0
HKD1_k127_7757702_3 PFAM Methicillin resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 347.0
HKD1_k127_7757702_4 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 360.0
HKD1_k127_7757702_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000001002 198.0
HKD1_k127_7861227_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.047e-291 916.0
HKD1_k127_7861227_1 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 546.0
HKD1_k127_7861227_10 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002852 267.0
HKD1_k127_7861227_11 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006022 247.0
HKD1_k127_7861227_12 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000004509 209.0
HKD1_k127_7861227_14 PFAM SMC domain protein K03546 - - 0.000000000000000000000000000003395 121.0
HKD1_k127_7861227_16 CoA binding domain K06929 - - 0.00000000000000000000000002574 113.0
HKD1_k127_7861227_17 - - - - 0.00000003189 58.0
HKD1_k127_7861227_2 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000697 458.0
HKD1_k127_7861227_3 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 428.0
HKD1_k127_7861227_4 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 390.0
HKD1_k127_7861227_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 356.0
HKD1_k127_7861227_6 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 337.0
HKD1_k127_7861227_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 342.0
HKD1_k127_7861227_8 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 304.0
HKD1_k127_7861227_9 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 294.0
HKD1_k127_7967037_0 Protein of unknown function, DUF255 K06888 - - 1.542e-228 727.0
HKD1_k127_7967037_1 PFAM glycosidase PH1107-related K18785,K20885 - 2.4.1.319,2.4.1.320,2.4.1.339,2.4.1.340 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 539.0
HKD1_k127_7967037_10 serine-type aminopeptidase activity - - - 0.000003918 59.0
HKD1_k127_7967037_2 MFS/sugar transport protein K03292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 444.0
HKD1_k127_7967037_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 383.0
HKD1_k127_7967037_4 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009168 276.0
HKD1_k127_7967037_5 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000005792 197.0
HKD1_k127_7967037_6 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000001874 177.0
HKD1_k127_7967037_7 Ergosterol biosynthesis ERG4/ERG24 family - - - 0.0000000000000000000000000000000000000000005382 164.0
HKD1_k127_7967037_8 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000007421 145.0
HKD1_k127_7967037_9 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000005041 111.0
HKD1_k127_83560_0 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 3.259e-213 694.0
HKD1_k127_83560_1 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 7.121e-195 619.0
HKD1_k127_83560_10 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000003314 250.0
HKD1_k127_83560_11 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000003133 221.0
HKD1_k127_83560_12 Transcriptional regulator IclR K13641 - - 0.0000000000000000000000000000000000000000000000000000001097 204.0
HKD1_k127_83560_13 transmembrane transport K01992 - - 0.00000000000000000000000000000000000000001216 162.0
HKD1_k127_83560_14 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000171 149.0
HKD1_k127_83560_15 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000001308 135.0
HKD1_k127_83560_16 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000003179 134.0
HKD1_k127_83560_17 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000002848 128.0
HKD1_k127_83560_18 metal-dependent membrane protease - - - 0.000000000000000000000000006419 117.0
HKD1_k127_83560_19 PFAM pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000002602 111.0
HKD1_k127_83560_2 ABC transporter K10441,K10562 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 517.0
HKD1_k127_83560_20 - - - - 0.000000000000002728 78.0
HKD1_k127_83560_3 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 501.0
HKD1_k127_83560_4 Transcriptional regulator K02529,K07506 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 491.0
HKD1_k127_83560_5 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 339.0
HKD1_k127_83560_6 PFAM Transaldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 333.0
HKD1_k127_83560_7 Branched-chain amino acid transport system / permease component K02057,K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 320.0
HKD1_k127_83560_8 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 319.0
HKD1_k127_83560_9 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000009581 245.0
HKD1_k127_858701_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1110.0
HKD1_k127_858701_1 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 7.96e-296 926.0
HKD1_k127_858701_10 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007975 413.0
HKD1_k127_858701_11 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 396.0
HKD1_k127_858701_12 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 398.0
HKD1_k127_858701_13 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 398.0
HKD1_k127_858701_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 351.0
HKD1_k127_858701_15 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 346.0
HKD1_k127_858701_16 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 332.0
HKD1_k127_858701_17 PFAM deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 302.0
HKD1_k127_858701_18 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001758 277.0
HKD1_k127_858701_19 PFAM secretion protein HlyD family protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000003881 252.0
HKD1_k127_858701_2 Lysine-2,3-aminomutase K01843 - 5.4.3.2 2.282e-230 720.0
HKD1_k127_858701_20 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000000000000000000000000000003051 220.0
HKD1_k127_858701_21 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.0000000000000000000000000000000000000000000000000000000003632 211.0
HKD1_k127_858701_22 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000001269 181.0
HKD1_k127_858701_24 domain, Protein - - - 0.000000000000000000000000000001095 134.0
HKD1_k127_858701_25 alpha, beta K06889 - - 0.00000000000000000000000008845 117.0
HKD1_k127_858701_27 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000006349 57.0
HKD1_k127_858701_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 5.912e-226 705.0
HKD1_k127_858701_4 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 2.635e-209 661.0
HKD1_k127_858701_5 metalloendopeptidase activity K08602 - - 1.684e-206 656.0
HKD1_k127_858701_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 517.0
HKD1_k127_858701_7 aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 496.0
HKD1_k127_858701_8 PFAM Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 454.0
HKD1_k127_858701_9 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 451.0
HKD1_k127_875937_0 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0 1074.0
HKD1_k127_875937_1 PFAM Pyridoxal-dependent decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 563.0
HKD1_k127_875937_2 pilus organization K02674,K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 380.0
HKD1_k127_875937_3 Domain present in PSD-95, Dlg, and ZO-1/2. K04771,K08070 - 1.3.1.74,3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 305.0
HKD1_k127_875937_4 methyltransferase - - - 0.000000000000000000000000000001057 125.0
HKD1_k127_898440_0 Bacterial extracellular solute-binding protein K10117 - - 6.303e-195 617.0
HKD1_k127_898440_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 535.0
HKD1_k127_898440_10 PFAM thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 306.0
HKD1_k127_898440_11 Putative esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 312.0
HKD1_k127_898440_12 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 300.0
HKD1_k127_898440_13 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 297.0
HKD1_k127_898440_14 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003019 262.0
HKD1_k127_898440_15 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000000000000000000000000000000000000000007042 236.0
HKD1_k127_898440_16 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000003495 205.0
HKD1_k127_898440_17 sh3 domain protein K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000797 176.0
HKD1_k127_898440_18 GAF domain - - - 0.000000000000000000000000000000000000000000001268 180.0
HKD1_k127_898440_19 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000003812 163.0
HKD1_k127_898440_2 SMART alpha amylase, catalytic sub domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 466.0
HKD1_k127_898440_20 maltose binding K15770,K15771 - - 0.0000000000000000000000000000000000008284 159.0
HKD1_k127_898440_21 Protein of unknown function (DUF4230) - - - 0.00000000000000000000000000000000001749 144.0
HKD1_k127_898440_22 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000004058 131.0
HKD1_k127_898440_23 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000005845 128.0
HKD1_k127_898440_24 Ribosomal L27 protein K02899 - - 0.0000000000000000000000000000007674 123.0
HKD1_k127_898440_25 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000002631 121.0
HKD1_k127_898440_26 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000000000000001449 108.0
HKD1_k127_898440_27 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000141 108.0
HKD1_k127_898440_28 PFAM response regulator receiver K02483,K07669 - - 0.00000000000000000000955 96.0
HKD1_k127_898440_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 396.0
HKD1_k127_898440_30 histone H2A K63-linked ubiquitination - - - 0.000003143 56.0
HKD1_k127_898440_4 Binding-protein-dependent transport system inner membrane component K10119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 395.0
HKD1_k127_898440_5 ABC transporter K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 385.0
HKD1_k127_898440_6 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 390.0
HKD1_k127_898440_7 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 358.0
HKD1_k127_898440_8 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 344.0
HKD1_k127_898440_9 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 317.0
HKD1_k127_966498_0 Alpha amylase, catalytic domain - - - 0.0 1412.0
HKD1_k127_966498_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.29e-282 889.0
HKD1_k127_966498_10 tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 574.0
HKD1_k127_966498_11 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 540.0
HKD1_k127_966498_12 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 530.0
HKD1_k127_966498_13 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 528.0
HKD1_k127_966498_14 PFAM extracellular solute-binding protein family 1 K10117,K17315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 510.0
HKD1_k127_966498_15 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 445.0
HKD1_k127_966498_16 Oxidoreductase family, NAD-binding Rossmann fold K00118,K13020 - 1.1.1.335,1.1.99.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 419.0
HKD1_k127_966498_17 nitrite transmembrane transporter activity K02532 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 408.0
HKD1_k127_966498_18 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 406.0
HKD1_k127_966498_19 NB-ARC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 436.0
HKD1_k127_966498_2 Aromatic amino acid lyase K01745 - 4.3.1.3 8.843e-260 809.0
HKD1_k127_966498_20 PFAM sodium calcium exchanger membrane region K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 400.0
HKD1_k127_966498_21 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 393.0
HKD1_k127_966498_22 Binding-protein-dependent transport system inner membrane component K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 385.0
HKD1_k127_966498_23 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 378.0
HKD1_k127_966498_24 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 357.0
HKD1_k127_966498_25 Binding-protein-dependent transport system inner membrane component K17317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 359.0
HKD1_k127_966498_26 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 357.0
HKD1_k127_966498_27 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 348.0
HKD1_k127_966498_28 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 341.0
HKD1_k127_966498_29 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 323.0
HKD1_k127_966498_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.313e-240 754.0
HKD1_k127_966498_30 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 317.0
HKD1_k127_966498_31 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 316.0
HKD1_k127_966498_32 pfam rok - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 302.0
HKD1_k127_966498_33 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 297.0
HKD1_k127_966498_34 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 294.0
HKD1_k127_966498_35 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007562 257.0
HKD1_k127_966498_36 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001309 251.0
HKD1_k127_966498_37 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001777 267.0
HKD1_k127_966498_38 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000007906 248.0
HKD1_k127_966498_39 Cytochrome b/b6/petB K00412,K03888 - - 0.00000000000000000000000000000000000000000000000000000000000000000004317 237.0
HKD1_k127_966498_4 domain, Protein K01219,K17624 - 3.2.1.81,3.2.1.97 5.054e-223 713.0
HKD1_k127_966498_40 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000003033 223.0
HKD1_k127_966498_41 Helix-turn-helix type 11 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000002118 227.0
HKD1_k127_966498_42 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000002138 226.0
HKD1_k127_966498_43 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000002766 230.0
HKD1_k127_966498_44 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000005443 227.0
HKD1_k127_966498_45 4-vinyl reductase, 4VR - - - 0.000000000000000000000000000000000000000000000000000000000001011 216.0
HKD1_k127_966498_46 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000724 218.0
HKD1_k127_966498_47 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.000000000000000000000000000000000000000000000000000000297 197.0
HKD1_k127_966498_48 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000002562 196.0
HKD1_k127_966498_49 PFAM Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000000000000000000009793 188.0
HKD1_k127_966498_5 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 7.821e-221 694.0
HKD1_k127_966498_50 COG0437 Fe-S-cluster-containing hydrogenase components 1 K00184 - - 0.000000000000000000000000000000000000000000000000002141 193.0
HKD1_k127_966498_51 Thiamine-binding protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000834 162.0
HKD1_k127_966498_52 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000005606 168.0
HKD1_k127_966498_53 PFAM DegV family protein - - - 0.000000000000000000000000000000000000000002053 167.0
HKD1_k127_966498_54 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000005848 151.0
HKD1_k127_966498_55 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000002256 165.0
HKD1_k127_966498_56 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000000000000000001151 147.0
HKD1_k127_966498_57 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000005287 145.0
HKD1_k127_966498_58 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000001723 138.0
HKD1_k127_966498_59 G5 domain protein - - - 0.00000000000000000000000000000000002985 151.0
HKD1_k127_966498_6 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.269e-202 646.0
HKD1_k127_966498_60 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000001236 143.0
HKD1_k127_966498_61 4Fe-4S binding domain - - - 0.00000000000000000000000000000003844 129.0
HKD1_k127_966498_62 lipid kinase, YegS Rv2252 BmrU family - - - 0.0000000000000000000000000000004636 134.0
HKD1_k127_966498_63 PFAM helix-turn-helix- domain containing protein, AraC type K13653 - - 0.0000000000000000000000000005362 120.0
HKD1_k127_966498_64 Rieske [2Fe-2S] domain K03886 - - 0.00000000000000000000000001488 115.0
HKD1_k127_966498_65 Cytochrome b(C-terminal)/b6/petD K03888 - - 0.00000000000000000000000004129 125.0
HKD1_k127_966498_66 PFAM DegV family protein - - - 0.000000000000000000000001425 114.0
HKD1_k127_966498_67 ribosomal protein L28 K02902 - - 0.000000000000000006412 84.0
HKD1_k127_966498_68 - - - - 0.0000000000000002084 85.0
HKD1_k127_966498_69 Cytochrome c554 and c-prime - - - 0.000000000002905 78.0
HKD1_k127_966498_7 PFAM Dak phosphatase K07030 - - 3.886e-202 644.0
HKD1_k127_966498_70 Cytochrome c - - - 0.0000000004959 73.0
HKD1_k127_966498_71 Transcriptional regulator PadR-like family K10947 - - 0.00000000945 62.0
HKD1_k127_966498_72 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000002198 64.0
HKD1_k127_966498_73 extracellular polysaccharide biosynthetic process - - - 0.0000005488 59.0
HKD1_k127_966498_74 ThiS family - - - 0.00003748 50.0
HKD1_k127_966498_8 PHP domain protein K02347 - - 6.684e-202 644.0
HKD1_k127_966498_9 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 610.0
HKD1_k127_982034_0 PFAM basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 340.0
HKD1_k127_982034_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 322.0
HKD1_k127_982034_2 Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000000000000002787 189.0
HKD1_k127_982034_3 Domain of unknown function (DUF389) - - - 0.0000000000000000000000000000000000000000004199 170.0
HKD1_k127_982034_4 ABC transporter substrate-binding protein PnrA-like K02058,K05519,K07335 - - 0.000000000000000000000000000002921 134.0