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Overview

ID MAG01712
Name HKD1_bin.26
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Methylomirabilota
Class Methylomirabilia
Order Rokubacteriales
Family JACPHL01
Genus
Species
Assembly information
Completeness (%) 98.59
Contamination (%) 2.19
GC content (%) 74.0
N50 (bp) 60,528
Genome size (bp) 4,640,187

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4086

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1008850_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 6.771e-262 831.0
HKD1_k127_1008850_1 FAD dependent oxidoreductase - - - 2.21e-238 749.0
HKD1_k127_1008850_10 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 446.0
HKD1_k127_1008850_11 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 447.0
HKD1_k127_1008850_12 ABC-type uncharacterized transport system K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 437.0
HKD1_k127_1008850_13 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 450.0
HKD1_k127_1008850_14 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 432.0
HKD1_k127_1008850_15 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 415.0
HKD1_k127_1008850_16 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 410.0
HKD1_k127_1008850_17 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 378.0
HKD1_k127_1008850_18 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 368.0
HKD1_k127_1008850_19 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 354.0
HKD1_k127_1008850_2 May be the GTPase, regulating ATP sulfurylase activity K00955 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237 2.7.1.25,2.7.7.4 1.527e-218 696.0
HKD1_k127_1008850_20 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 350.0
HKD1_k127_1008850_21 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 351.0
HKD1_k127_1008850_22 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 339.0
HKD1_k127_1008850_23 ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 371.0
HKD1_k127_1008850_24 sulfate adenylyltransferase), subunit 2 K00957 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0070566,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 341.0
HKD1_k127_1008850_25 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 338.0
HKD1_k127_1008850_26 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 313.0
HKD1_k127_1008850_27 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 320.0
HKD1_k127_1008850_28 Belongs to the cysteine synthase cystathionine beta- synthase family K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000181 278.0
HKD1_k127_1008850_29 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001126 258.0
HKD1_k127_1008850_3 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 3.129e-215 689.0
HKD1_k127_1008850_30 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K20435 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000003768 255.0
HKD1_k127_1008850_31 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009874 255.0
HKD1_k127_1008850_32 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001415 245.0
HKD1_k127_1008850_33 Integral membrane protein TerC family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000003687 236.0
HKD1_k127_1008850_34 Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source K05396,K17950 - 4.4.1.15,4.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000746 244.0
HKD1_k127_1008850_35 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000004683 233.0
HKD1_k127_1008850_36 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000001275 228.0
HKD1_k127_1008850_37 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000004643 228.0
HKD1_k127_1008850_38 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000002948 218.0
HKD1_k127_1008850_39 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000003135 213.0
HKD1_k127_1008850_4 amino acid - - - 2.488e-210 670.0
HKD1_k127_1008850_40 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000005998 220.0
HKD1_k127_1008850_41 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000001168 198.0
HKD1_k127_1008850_42 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000002806 192.0
HKD1_k127_1008850_43 Beta-lactamase enzyme family K07258,K07262 - 3.4.16.4 0.0000000000000000000000000000000000000000000000001872 189.0
HKD1_k127_1008850_44 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000008485 183.0
HKD1_k127_1008850_45 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000002187 174.0
HKD1_k127_1008850_46 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000003052 162.0
HKD1_k127_1008850_47 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000007115 172.0
HKD1_k127_1008850_48 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.000000000000000000000000000000007458 139.0
HKD1_k127_1008850_49 Methyltransferase domain K07003 - - 0.00000000000000000000000000000000845 145.0
HKD1_k127_1008850_5 RecQ zinc-binding K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 589.0
HKD1_k127_1008850_50 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000742 138.0
HKD1_k127_1008850_52 Peptidase_C39 like family - - - 0.000000000000000000000000000001394 130.0
HKD1_k127_1008850_53 Endoribonuclease L-PSP - - - 0.000000000000000000000000000001614 127.0
HKD1_k127_1008850_54 Cbs domain K04767 - - 0.00000000000000000000000003326 121.0
HKD1_k127_1008850_55 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000335 115.0
HKD1_k127_1008850_56 Bifunctional nuclease K08999 - - 0.0000000000000000000000004845 121.0
HKD1_k127_1008850_57 Oxidoreductase family, NAD-binding Rossmann fold K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000007425 119.0
HKD1_k127_1008850_58 Proto-chlorophyllide reductase 57 kd subunit - - - 0.000000000000000000000001073 111.0
HKD1_k127_1008850_59 Aldo keto reductase K00064 - 1.1.1.122 0.000000000000000002811 98.0
HKD1_k127_1008850_6 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 545.0
HKD1_k127_1008850_61 HPr kinase - - - 0.000000000001636 79.0
HKD1_k127_1008850_62 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000006405 72.0
HKD1_k127_1008850_63 - - - - 0.000000005776 64.0
HKD1_k127_1008850_66 NYN domain - - - 0.000007951 59.0
HKD1_k127_1008850_69 negative regulation of translational initiation - - - 0.0002602 51.0
HKD1_k127_1008850_7 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 465.0
HKD1_k127_1008850_70 Aldo/keto reductase family K00064 - 1.1.1.122 0.0003371 47.0
HKD1_k127_1008850_8 Belongs to the FGGY kinase family K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 470.0
HKD1_k127_1008850_9 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 456.0
HKD1_k127_102714_0 DEAD DEAH box K03724 - - 0.0 1623.0
HKD1_k127_102714_1 histidine kinase, HAMP K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 578.0
HKD1_k127_102714_10 Domain of unknown function (DUF4390) - - - 0.00004455 53.0
HKD1_k127_102714_2 response regulator K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 542.0
HKD1_k127_102714_3 Protein of unknown function (DUF1116) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 486.0
HKD1_k127_102714_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 465.0
HKD1_k127_102714_5 CoA-ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 363.0
HKD1_k127_102714_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K16363 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000113 245.0
HKD1_k127_102714_7 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000003155 86.0
HKD1_k127_102714_8 Protein of unknown function (DUF2877) - - - 0.00000000005532 74.0
HKD1_k127_102714_9 CoA-ligase K02381 - - 0.000000001661 67.0
HKD1_k127_1039427_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 503.0
HKD1_k127_1039427_1 KaiC K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 512.0
HKD1_k127_1039427_10 - - - - 0.000000000000002317 84.0
HKD1_k127_1039427_11 Psort location Cytoplasmic, score K01523 - 3.6.1.31 0.00000886 48.0
HKD1_k127_1039427_12 - - - - 0.00003056 54.0
HKD1_k127_1039427_2 Large family of predicted nucleotide-binding domains - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 304.0
HKD1_k127_1039427_3 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001823 251.0
HKD1_k127_1039427_4 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000001744 238.0
HKD1_k127_1039427_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000008192 223.0
HKD1_k127_1039427_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000002332 186.0
HKD1_k127_1039427_7 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000008426 189.0
HKD1_k127_1039427_8 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000002428 184.0
HKD1_k127_1039427_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.00000000000000000005256 91.0
HKD1_k127_1040525_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1011.0
HKD1_k127_1040525_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 8.789e-279 895.0
HKD1_k127_1040525_10 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002293 279.0
HKD1_k127_1040525_11 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001863 248.0
HKD1_k127_1040525_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002177 232.0
HKD1_k127_1040525_13 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.0000000000000000000000000000000000000000000000000000000000001859 227.0
HKD1_k127_1040525_14 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000001949 184.0
HKD1_k127_1040525_15 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000000000002056 167.0
HKD1_k127_1040525_16 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000001877 122.0
HKD1_k127_1040525_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000006517 127.0
HKD1_k127_1040525_18 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000004168 109.0
HKD1_k127_1040525_19 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000004392 85.0
HKD1_k127_1040525_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 3.068e-243 759.0
HKD1_k127_1040525_20 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000005075 81.0
HKD1_k127_1040525_21 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000193 72.0
HKD1_k127_1040525_22 Protein of unknown function (DUF507) K09804 - - 0.000000000001678 72.0
HKD1_k127_1040525_23 PFAM IstB domain protein ATP-binding protein - - - 0.0000002489 58.0
HKD1_k127_1040525_24 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000006925 54.0
HKD1_k127_1040525_26 Protein of unknown function (DUF507) - - - 0.0008917 49.0
HKD1_k127_1040525_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 3.062e-240 760.0
HKD1_k127_1040525_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 506.0
HKD1_k127_1040525_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 460.0
HKD1_k127_1040525_6 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 357.0
HKD1_k127_1040525_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 343.0
HKD1_k127_1040525_8 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002359 283.0
HKD1_k127_1040525_9 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001289 287.0
HKD1_k127_1097341_0 Berberine and berberine like - - - 5.499e-229 724.0
HKD1_k127_1097341_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 383.0
HKD1_k127_1097341_11 Sulfatase K01130 - 3.1.6.1 0.00001003 51.0
HKD1_k127_1097341_2 cysteine-tRNA ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 351.0
HKD1_k127_1097341_3 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000008843 227.0
HKD1_k127_1097341_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000001356 220.0
HKD1_k127_1097341_5 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000002195 204.0
HKD1_k127_1097341_6 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000004207 187.0
HKD1_k127_1097341_7 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.00000000000000000000000000000000000000000448 164.0
HKD1_k127_1097341_8 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000008274 131.0
HKD1_k127_1097341_9 Substrate binding domain of ABC-type glycine betaine transport system K02051,K15553 - - 0.00000000002073 77.0
HKD1_k127_1135638_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 447.0
HKD1_k127_1135638_1 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000009656 231.0
HKD1_k127_1135638_2 Protein of unknown function (DUF2652) - - - 0.000000000000000000001214 101.0
HKD1_k127_1135638_3 Antibiotic biosynthesis monooxygenase - - - 0.00000000000002008 79.0
HKD1_k127_1135638_4 TPR repeat - - - 0.00000000004319 73.0
HKD1_k127_1229203_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 449.0
HKD1_k127_1229203_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000563 232.0
HKD1_k127_1229203_2 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000004575 210.0
HKD1_k127_1229203_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000001124 188.0
HKD1_k127_1229203_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000000000000001507 160.0
HKD1_k127_1229203_5 Variant erythrocyte surface antigen-1 - - - 0.0005076 46.0
HKD1_k127_1240110_0 Domain of unknown function (DUF3536) - - - 7.148e-211 685.0
HKD1_k127_1240110_1 COG0076 Glutamate decarboxylase and related PLP-dependent K01593,K13745 - 4.1.1.105,4.1.1.28,4.1.1.86 2.181e-206 653.0
HKD1_k127_1240110_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 359.0
HKD1_k127_1240110_11 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 365.0
HKD1_k127_1240110_12 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 327.0
HKD1_k127_1240110_13 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 328.0
HKD1_k127_1240110_14 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 312.0
HKD1_k127_1240110_15 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002422 300.0
HKD1_k127_1240110_16 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008762 281.0
HKD1_k127_1240110_17 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004443 286.0
HKD1_k127_1240110_18 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009703 286.0
HKD1_k127_1240110_19 TIGRFAM geranylgeranyl reductase K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000002177 267.0
HKD1_k127_1240110_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 518.0
HKD1_k127_1240110_20 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000006731 262.0
HKD1_k127_1240110_21 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009235 250.0
HKD1_k127_1240110_22 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000002353 248.0
HKD1_k127_1240110_23 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16164 - 3.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000001598 244.0
HKD1_k127_1240110_24 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000328 245.0
HKD1_k127_1240110_25 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000003426 237.0
HKD1_k127_1240110_26 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000169 242.0
HKD1_k127_1240110_27 HpcH/HpaI aldolase/citrate lyase family K02510,K12660 - 4.1.2.52,4.1.2.53 0.00000000000000000000000000000000000000000000000000000000000001274 226.0
HKD1_k127_1240110_28 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000006867 218.0
HKD1_k127_1240110_29 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.0000000000000000000000000000000000000000000000000000000000101 218.0
HKD1_k127_1240110_3 protease-associated PA domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 480.0
HKD1_k127_1240110_30 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000003395 208.0
HKD1_k127_1240110_31 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000000000000000000007348 212.0
HKD1_k127_1240110_32 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000001092 191.0
HKD1_k127_1240110_33 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000007224 201.0
HKD1_k127_1240110_34 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000001206 205.0
HKD1_k127_1240110_35 Methyltransferase domain - - - 0.00000000000000000000000000000000000000002421 163.0
HKD1_k127_1240110_36 Haloacid dehalogenase-like hydrolase K01101 - 3.1.3.41 0.00000000000000000000000000000000003575 149.0
HKD1_k127_1240110_37 Catalytic LigB subunit of aromatic ring-opening dioxygenase K00455 - 1.13.11.15 0.0000000000000000000000000000000008991 139.0
HKD1_k127_1240110_38 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000001676 138.0
HKD1_k127_1240110_39 RNA recognition motif - - - 0.000000000000000000000003781 108.0
HKD1_k127_1240110_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 444.0
HKD1_k127_1240110_40 Protein of unknown function (DUF3303) - - - 0.000000000000000000008689 106.0
HKD1_k127_1240110_41 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000003357 87.0
HKD1_k127_1240110_42 DinB superfamily - - - 0.0000000000000002135 85.0
HKD1_k127_1240110_43 hydroperoxide reductase activity - - - 0.000000000002756 78.0
HKD1_k127_1240110_44 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000004877 80.0
HKD1_k127_1240110_45 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000007057 68.0
HKD1_k127_1240110_46 monooxygenase activity - - - 0.0000009344 54.0
HKD1_k127_1240110_47 Vitamin B12 dependent methionine synthase, activation domain - - - 0.0000595 53.0
HKD1_k127_1240110_48 FecR protein - - - 0.0001141 55.0
HKD1_k127_1240110_5 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 442.0
HKD1_k127_1240110_6 Chalcone and stilbene synthases, C-terminal domain K16424 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.246 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 415.0
HKD1_k127_1240110_7 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 431.0
HKD1_k127_1240110_8 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 400.0
HKD1_k127_1240110_9 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 380.0
HKD1_k127_1318004_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 6.181e-222 713.0
HKD1_k127_1318004_1 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 418.0
HKD1_k127_1318004_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000001269 194.0
HKD1_k127_1318004_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000003066 177.0
HKD1_k127_1318004_12 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000005319 189.0
HKD1_k127_1318004_13 dioxygenase activity K00477,K10674,K15650 - 1.14.11.18,1.14.11.55 0.0000000000000000000000000000000000000000001017 179.0
HKD1_k127_1318004_14 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000005463 164.0
HKD1_k127_1318004_15 FCD K11475 - - 0.0000000000000000002536 98.0
HKD1_k127_1318004_16 Acetyltransferase (GNAT) family - - - 0.0007626 51.0
HKD1_k127_1318004_2 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 364.0
HKD1_k127_1318004_3 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 338.0
HKD1_k127_1318004_4 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 330.0
HKD1_k127_1318004_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 310.0
HKD1_k127_1318004_6 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000004458 244.0
HKD1_k127_1318004_7 Pyridoxal-phosphate dependent enzyme K05396,K17950 - 4.4.1.15,4.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000005234 238.0
HKD1_k127_1318004_8 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000002571 245.0
HKD1_k127_1318004_9 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000002196 230.0
HKD1_k127_1344313_0 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 494.0
HKD1_k127_1344313_1 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 485.0
HKD1_k127_1344313_10 - - - - 0.00000000000000000000000000000000000000000000000000000000001335 221.0
HKD1_k127_1344313_11 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000001649 209.0
HKD1_k127_1344313_12 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.00002382 57.0
HKD1_k127_1344313_2 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 465.0
HKD1_k127_1344313_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 408.0
HKD1_k127_1344313_4 Iron-containing alcohol dehydrogenase K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 399.0
HKD1_k127_1344313_5 asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 404.0
HKD1_k127_1344313_6 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 358.0
HKD1_k127_1344313_7 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 359.0
HKD1_k127_1344313_8 2-Nitropropane dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001028 276.0
HKD1_k127_1390842_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652,K03852 - 2.2.1.6,2.3.3.15 1.99e-250 785.0
HKD1_k127_1390842_1 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 483.0
HKD1_k127_1390842_10 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000001587 141.0
HKD1_k127_1390842_11 Amidohydrolase K07045 - - 0.000000000000000000000000000215 126.0
HKD1_k127_1390842_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 392.0
HKD1_k127_1390842_3 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 360.0
HKD1_k127_1390842_4 COGs COG0569 K transport systems NAD-binding component K03499,K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001471 280.0
HKD1_k127_1390842_5 COG1921 Selenocysteine synthase seryl-tRNASer selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000003441 263.0
HKD1_k127_1390842_6 hydratase K01617,K02554 - 4.1.1.77,4.2.1.80 0.000000000000000000000000000000000000008215 165.0
HKD1_k127_1390842_7 Amidohydrolase - - - 0.00000000000000000000000000000000000005876 153.0
HKD1_k127_1390842_8 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000047 153.0
HKD1_k127_1390842_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000966 144.0
HKD1_k127_1409027_0 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008904 257.0
HKD1_k127_1409027_1 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000006983 186.0
HKD1_k127_1409027_2 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000006962 143.0
HKD1_k127_1409027_3 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000001836 120.0
HKD1_k127_1409027_4 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.00000000000000000004186 90.0
HKD1_k127_147173_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.454e-223 717.0
HKD1_k127_147173_1 Hydantoinase B/oxoprolinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 604.0
HKD1_k127_147173_10 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001974 270.0
HKD1_k127_147173_11 PFAM Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001935 259.0
HKD1_k127_147173_12 Binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002856 262.0
HKD1_k127_147173_13 Allophanate hydrolase subunit 1 K06351 - - 0.000000000000000000000000000000000000000000000000000000000000000006044 235.0
HKD1_k127_147173_14 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000006244 232.0
HKD1_k127_147173_15 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005715 237.0
HKD1_k127_147173_16 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000009058 236.0
HKD1_k127_147173_17 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000001128 193.0
HKD1_k127_147173_18 PFAM 2Fe-2S -binding K03518,K13483 - 1.2.5.3 0.000000000000000000000000000000000000002218 169.0
HKD1_k127_147173_19 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000003961 156.0
HKD1_k127_147173_2 Hydantoinase/oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 511.0
HKD1_k127_147173_20 PAS domain - - - 0.0000000000000000000000000000000000007024 144.0
HKD1_k127_147173_21 oxidation-reduction process - - - 0.00000000000000000000000001214 114.0
HKD1_k127_147173_22 Sugar (and other) transporter K07552 - - 0.000001714 62.0
HKD1_k127_147173_3 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 478.0
HKD1_k127_147173_4 conserved protein (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 361.0
HKD1_k127_147173_5 Protein of unknown function (DUF1445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 370.0
HKD1_k127_147173_6 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 328.0
HKD1_k127_147173_7 Allophanate hydrolase subunit 2 K06350 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009631 322.0
HKD1_k127_147173_8 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004776 300.0
HKD1_k127_147173_9 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004593 297.0
HKD1_k127_1538349_0 Adenylate and Guanylate cyclase catalytic domain - - - 3.668e-286 919.0
HKD1_k127_1538349_1 (ABC) transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 608.0
HKD1_k127_1538349_10 Ankyrin repeat - - - 0.0008169 49.0
HKD1_k127_1538349_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 514.0
HKD1_k127_1538349_3 Methionine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 474.0
HKD1_k127_1538349_4 PFAM extracellular solute-binding protein family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 473.0
HKD1_k127_1538349_5 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 389.0
HKD1_k127_1538349_6 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 314.0
HKD1_k127_1538349_7 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 291.0
HKD1_k127_1538349_8 PFAM binding-protein-dependent transport systems inner membrane component K02033,K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006501 285.0
HKD1_k127_1538349_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001042 261.0
HKD1_k127_157683_0 carbamoyl transferase, NodU family K00612 - - 6.37e-210 678.0
HKD1_k127_157683_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 450.0
HKD1_k127_157683_10 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000004759 234.0
HKD1_k127_157683_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000009421 220.0
HKD1_k127_157683_12 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000325 216.0
HKD1_k127_157683_13 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000003547 212.0
HKD1_k127_157683_14 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000006128 191.0
HKD1_k127_157683_15 Glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000001747 204.0
HKD1_k127_157683_16 geranylgeranyl reductase activity K06444,K17830 - 1.3.1.101,1.3.7.11,5.5.1.18 0.00000000000000000000000000000000000000000000000009157 203.0
HKD1_k127_157683_17 2OG-Fe(II) oxygenase superfamily K07336,K07394 - - 0.0000000000000000000000000000007129 131.0
HKD1_k127_157683_18 - - - - 0.0000000000000000000000000000007347 138.0
HKD1_k127_157683_19 deoxyhypusine monooxygenase activity K08884 - 2.7.11.1 0.000000000000000000000000000001274 140.0
HKD1_k127_157683_2 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 301.0
HKD1_k127_157683_20 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000001266 130.0
HKD1_k127_157683_21 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.00000000000000000000000000855 128.0
HKD1_k127_157683_22 Cof-like hydrolase - - - 0.0000000001528 64.0
HKD1_k127_157683_23 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000002832 63.0
HKD1_k127_157683_24 Cyclic nucleotide-monophosphate binding domain - - - 0.0000001836 63.0
HKD1_k127_157683_25 DUF218 domain - - - 0.0000002783 64.0
HKD1_k127_157683_26 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00001416 56.0
HKD1_k127_157683_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 303.0
HKD1_k127_157683_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002837 286.0
HKD1_k127_157683_5 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006123 286.0
HKD1_k127_157683_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001774 301.0
HKD1_k127_157683_7 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005627 272.0
HKD1_k127_157683_8 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003617 274.0
HKD1_k127_157683_9 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000003255 252.0
HKD1_k127_163511_0 ABC transporter, ATP-binding protein K13926 - - 0.0 1170.0
HKD1_k127_163511_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.454e-209 657.0
HKD1_k127_163511_10 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 460.0
HKD1_k127_163511_11 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 451.0
HKD1_k127_163511_12 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 448.0
HKD1_k127_163511_13 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 477.0
HKD1_k127_163511_14 4fe-4S ferredoxin, iron-sulfur binding domain protein K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 423.0
HKD1_k127_163511_15 Bacterial sugar transferase K03606 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 438.0
HKD1_k127_163511_16 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 424.0
HKD1_k127_163511_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 407.0
HKD1_k127_163511_18 Aminotransferase class-V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 400.0
HKD1_k127_163511_19 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 400.0
HKD1_k127_163511_2 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 1.285e-199 676.0
HKD1_k127_163511_20 domain protein K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 364.0
HKD1_k127_163511_21 Sodium calcium exchanger membrane K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 378.0
HKD1_k127_163511_22 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 347.0
HKD1_k127_163511_23 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 357.0
HKD1_k127_163511_24 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 325.0
HKD1_k127_163511_25 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 335.0
HKD1_k127_163511_26 InterPro IPR008166 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001539 286.0
HKD1_k127_163511_27 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001673 291.0
HKD1_k127_163511_28 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000175 285.0
HKD1_k127_163511_29 Amidohydrolase family K01464,K01466 - 3.5.2.2,3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003432 294.0
HKD1_k127_163511_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008719 631.0
HKD1_k127_163511_30 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005924 278.0
HKD1_k127_163511_31 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000003364 276.0
HKD1_k127_163511_32 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003284 269.0
HKD1_k127_163511_34 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K16049 - 1.13.11.25 0.0000000000000000000000000000000000000000000000000000000000000000000000006964 258.0
HKD1_k127_163511_35 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003821 259.0
HKD1_k127_163511_36 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000001585 256.0
HKD1_k127_163511_37 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000000000000000000000000000337 252.0
HKD1_k127_163511_38 molybdenum ion binding K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000001045 235.0
HKD1_k127_163511_39 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001414 229.0
HKD1_k127_163511_4 Glucose inhibited division protein A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 601.0
HKD1_k127_163511_40 TIGRFAM Urea carboxylase-associated protein 1 K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000004884 229.0
HKD1_k127_163511_41 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000062 252.0
HKD1_k127_163511_42 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000008579 234.0
HKD1_k127_163511_43 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000001082 251.0
HKD1_k127_163511_44 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000002468 233.0
HKD1_k127_163511_45 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000002946 230.0
HKD1_k127_163511_46 fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000001716 226.0
HKD1_k127_163511_47 Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000001779 233.0
HKD1_k127_163511_48 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000001978 218.0
HKD1_k127_163511_49 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.0000000000000000000000000000000000000000000000000000000001303 215.0
HKD1_k127_163511_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 603.0
HKD1_k127_163511_50 Short-chain dehydrogenase reductase SDR K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000001587 213.0
HKD1_k127_163511_51 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000006434 213.0
HKD1_k127_163511_52 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000002319 192.0
HKD1_k127_163511_53 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000009614 181.0
HKD1_k127_163511_54 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000009799 189.0
HKD1_k127_163511_55 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000004439 182.0
HKD1_k127_163511_56 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000001035 173.0
HKD1_k127_163511_57 - - - - 0.000000000000000000000000000000000000000003006 169.0
HKD1_k127_163511_58 MaoC like domain K17865 - 4.2.1.55 0.0000000000000000000000000000000000000001052 160.0
HKD1_k127_163511_59 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000000000000000000000000000001557 168.0
HKD1_k127_163511_6 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 545.0
HKD1_k127_163511_60 phosphatase (DUF442) - - - 0.0000000000000000000000000000000000005017 146.0
HKD1_k127_163511_61 Protein of unknown function (DUF616) - - - 0.00000000000000000000000000000000002231 154.0
HKD1_k127_163511_62 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000002248 143.0
HKD1_k127_163511_63 PFAM luciferase-like - - - 0.000000000000000000000000000000134 136.0
HKD1_k127_163511_64 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000008722 124.0
HKD1_k127_163511_65 Involved in molybdopterin and thiamine biosynthesis, family 2 K03148,K21029,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.00000000000000000000000000003214 119.0
HKD1_k127_163511_66 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000332 130.0
HKD1_k127_163511_67 PA14 domain - - - 0.00000000000000000000000000007805 124.0
HKD1_k127_163511_68 Ion channel - - - 0.000000000000000000000000001799 129.0
HKD1_k127_163511_69 Hep Hag repeat protein - - - 0.000000000000000000000000002815 123.0
HKD1_k127_163511_7 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 481.0
HKD1_k127_163511_70 FR47-like protein K03829 - - 0.00000000000000000000000001376 125.0
HKD1_k127_163511_71 Polysaccharide biosynthesis protein - - - 0.0000000000000000002125 104.0
HKD1_k127_163511_72 DNA-sulfur modification-associated - - - 0.00000000000000005071 94.0
HKD1_k127_163511_74 Virulence factor - - - 0.000000000005334 71.0
HKD1_k127_163511_75 pfkB family carbohydrate kinase - - - 0.0000000000471 74.0
HKD1_k127_163511_76 Pfam:DUF955 - - - 0.000000001141 67.0
HKD1_k127_163511_77 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07291,K17884 - 2.7.8.34,2.7.8.39 0.000000002255 71.0
HKD1_k127_163511_79 - - - - 0.0000005418 56.0
HKD1_k127_163511_8 PFAM Xanthine uracil vitamin C permease K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 484.0
HKD1_k127_163511_80 Sugar (and other) transporter - - - 0.00001657 55.0
HKD1_k127_163511_82 - - - - 0.0006171 45.0
HKD1_k127_163511_9 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 479.0
HKD1_k127_1666642_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1109.0
HKD1_k127_1666642_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 4.472e-255 807.0
HKD1_k127_1666642_10 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 451.0
HKD1_k127_1666642_11 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 448.0
HKD1_k127_1666642_12 dUTP biosynthetic process K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008009 428.0
HKD1_k127_1666642_13 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 436.0
HKD1_k127_1666642_14 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00018 - 1.1.1.26,1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 422.0
HKD1_k127_1666642_15 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 395.0
HKD1_k127_1666642_16 Belongs to the peptidase M24B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 370.0
HKD1_k127_1666642_17 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 383.0
HKD1_k127_1666642_18 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 378.0
HKD1_k127_1666642_19 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 357.0
HKD1_k127_1666642_2 TIGRFAM FeS assembly protein SufB K09014 - - 2.859e-254 792.0
HKD1_k127_1666642_20 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 357.0
HKD1_k127_1666642_21 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 358.0
HKD1_k127_1666642_22 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 352.0
HKD1_k127_1666642_23 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 338.0
HKD1_k127_1666642_24 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 321.0
HKD1_k127_1666642_25 Domain of unknown function DUF108 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 312.0
HKD1_k127_1666642_26 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 316.0
HKD1_k127_1666642_27 Ketopantoate reductase PanE/ApbA K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 327.0
HKD1_k127_1666642_28 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 302.0
HKD1_k127_1666642_29 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 313.0
HKD1_k127_1666642_3 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 2.485e-196 616.0
HKD1_k127_1666642_30 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 291.0
HKD1_k127_1666642_31 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007287 277.0
HKD1_k127_1666642_32 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001115 274.0
HKD1_k127_1666642_33 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003641 271.0
HKD1_k127_1666642_34 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001147 267.0
HKD1_k127_1666642_35 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002135 279.0
HKD1_k127_1666642_36 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004341 280.0
HKD1_k127_1666642_37 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002045 258.0
HKD1_k127_1666642_38 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007255 260.0
HKD1_k127_1666642_39 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003531 252.0
HKD1_k127_1666642_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000718 617.0
HKD1_k127_1666642_40 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001618 262.0
HKD1_k127_1666642_41 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008877 254.0
HKD1_k127_1666642_42 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000003467 253.0
HKD1_k127_1666642_43 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000001262 257.0
HKD1_k127_1666642_44 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 239.0
HKD1_k127_1666642_45 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000006175 256.0
HKD1_k127_1666642_46 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000001501 237.0
HKD1_k127_1666642_47 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000002285 220.0
HKD1_k127_1666642_48 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000242 229.0
HKD1_k127_1666642_49 Binding-protein-dependent transport system inner membrane component K11082 - - 0.000000000000000000000000000000000000000000000000000000000004258 221.0
HKD1_k127_1666642_5 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 614.0
HKD1_k127_1666642_50 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000005465 215.0
HKD1_k127_1666642_51 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000001297 205.0
HKD1_k127_1666642_52 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000001925 190.0
HKD1_k127_1666642_53 amino acid ABC transporter K02029 - - 0.00000000000000000000000000000000000000000000000003362 186.0
HKD1_k127_1666642_54 NifU-like N terminal domain K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.0000000000000000000000000000000000000000000000001034 188.0
HKD1_k127_1666642_55 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000007245 179.0
HKD1_k127_1666642_56 actin binding - - - 0.00000000000000000000000000000000000000000000005164 173.0
HKD1_k127_1666642_57 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000003624 191.0
HKD1_k127_1666642_58 Gaf domain - - - 0.00000000000000000000000000000000000000000001424 179.0
HKD1_k127_1666642_59 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000002377 176.0
HKD1_k127_1666642_6 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 602.0
HKD1_k127_1666642_60 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000364 173.0
HKD1_k127_1666642_61 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000004741 179.0
HKD1_k127_1666642_62 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000006353 179.0
HKD1_k127_1666642_63 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000666 173.0
HKD1_k127_1666642_64 Cupin domain - - - 0.0000000000000000000000000000000000004772 157.0
HKD1_k127_1666642_65 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000000000001294 134.0
HKD1_k127_1666642_67 SMART Prolyl 4-hydroxylase, alpha subunit - - - 0.00000000000000000000000000000002505 147.0
HKD1_k127_1666642_68 Glycosyl transferase, family 2 - - - 0.00000000000000000000000001414 128.0
HKD1_k127_1666642_69 Thioredoxin-like domain K03671 - - 0.0000000000000000000000006063 119.0
HKD1_k127_1666642_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 497.0
HKD1_k127_1666642_70 Cytochrome c K08738 - - 0.000000000000000000004396 107.0
HKD1_k127_1666642_71 Nitroreductase family - - - 0.0000000000000000007191 102.0
HKD1_k127_1666642_72 metalloendopeptidase activity K03799 - - 0.00000000000000000215 102.0
HKD1_k127_1666642_73 - - - - 0.0000000000000006015 86.0
HKD1_k127_1666642_74 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000003763 69.0
HKD1_k127_1666642_8 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 475.0
HKD1_k127_1666642_9 formamidase K01455 - 3.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 473.0
HKD1_k127_1678833_0 Glycogen debranching enzyme - - - 0.0 1473.0
HKD1_k127_1678833_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 570.0
HKD1_k127_1678833_10 SMART ATPase, AAA type, core K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 353.0
HKD1_k127_1678833_11 daunorubicin resistance ABC transporter membrane protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 353.0
HKD1_k127_1678833_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 376.0
HKD1_k127_1678833_13 mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 330.0
HKD1_k127_1678833_14 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 309.0
HKD1_k127_1678833_15 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 311.0
HKD1_k127_1678833_16 HpcH/HpaI aldolase/citrate lyase family K01644,K14451 - 3.1.2.30,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000008145 241.0
HKD1_k127_1678833_17 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000006881 184.0
HKD1_k127_1678833_18 - - - - 0.00000000000000000000000000000000000002306 151.0
HKD1_k127_1678833_19 DinB superfamily - - - 0.00000000000000000000000000000000000003729 151.0
HKD1_k127_1678833_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 472.0
HKD1_k127_1678833_20 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000005006 130.0
HKD1_k127_1678833_21 Glycosyl transferase family group 2 - - - 0.00000000000000000000000004968 125.0
HKD1_k127_1678833_22 transferase activity, transferring glycosyl groups K07011,K13659 - 2.4.1.264 0.000000000000000000001845 108.0
HKD1_k127_1678833_23 Glycosyltransferase like family 2 K07011,K20444 - - 0.000000465 64.0
HKD1_k127_1678833_24 - - - - 0.0001286 55.0
HKD1_k127_1678833_25 Polysaccharide deacetylase - - - 0.000478 52.0
HKD1_k127_1678833_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 448.0
HKD1_k127_1678833_4 shikimate dehydrogenase K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 422.0
HKD1_k127_1678833_5 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 426.0
HKD1_k127_1678833_6 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 400.0
HKD1_k127_1678833_7 nitrogen compound transport K00759,K02033 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 396.0
HKD1_k127_1678833_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 392.0
HKD1_k127_1678833_9 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 389.0
HKD1_k127_1842602_0 DNA polymerase type-B family K02336 - 2.7.7.7 7.973e-319 1000.0
HKD1_k127_1842602_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.319e-227 719.0
HKD1_k127_1842602_10 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003271 256.0
HKD1_k127_1842602_11 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000009211 204.0
HKD1_k127_1842602_12 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K13995 - 3.5.1.107 0.000000000000000000000000000000004508 140.0
HKD1_k127_1842602_13 Putative FMN-binding domain K07734 - - 0.000000000000000000004975 95.0
HKD1_k127_1842602_14 Type II secretion system protein B K02451 - - 0.000000008651 66.0
HKD1_k127_1842602_15 Major Facilitator Superfamily - - - 0.0002481 53.0
HKD1_k127_1842602_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 606.0
HKD1_k127_1842602_3 COG0402 Cytosine deaminase and related metal-dependent hydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 509.0
HKD1_k127_1842602_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 407.0
HKD1_k127_1842602_5 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 357.0
HKD1_k127_1842602_6 amidohydrolase K01465 GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 322.0
HKD1_k127_1842602_7 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 294.0
HKD1_k127_1842602_8 transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002453 287.0
HKD1_k127_1842602_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001232 274.0
HKD1_k127_1962128_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 5.268e-255 806.0
HKD1_k127_1962128_1 4Fe-4S dicluster domain K00184 - - 4.768e-207 685.0
HKD1_k127_1962128_10 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 415.0
HKD1_k127_1962128_11 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 415.0
HKD1_k127_1962128_12 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 389.0
HKD1_k127_1962128_13 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 358.0
HKD1_k127_1962128_14 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 352.0
HKD1_k127_1962128_15 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 350.0
HKD1_k127_1962128_16 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 334.0
HKD1_k127_1962128_17 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 314.0
HKD1_k127_1962128_18 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 304.0
HKD1_k127_1962128_19 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 294.0
HKD1_k127_1962128_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.838e-203 644.0
HKD1_k127_1962128_20 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005633 276.0
HKD1_k127_1962128_21 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004473 281.0
HKD1_k127_1962128_22 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749,K13542 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000007403 271.0
HKD1_k127_1962128_23 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000226 252.0
HKD1_k127_1962128_24 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000001016 241.0
HKD1_k127_1962128_25 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000005902 245.0
HKD1_k127_1962128_26 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.000000000000000000000000000000000000000000000000000000000003103 230.0
HKD1_k127_1962128_27 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000001153 211.0
HKD1_k127_1962128_28 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000001335 206.0
HKD1_k127_1962128_29 Pfam Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000005152 181.0
HKD1_k127_1962128_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 617.0
HKD1_k127_1962128_30 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000001653 169.0
HKD1_k127_1962128_31 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000007529 169.0
HKD1_k127_1962128_32 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000001365 169.0
HKD1_k127_1962128_33 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.000000000000000000000000000000000000005654 155.0
HKD1_k127_1962128_34 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000005927 130.0
HKD1_k127_1962128_35 Transcriptional regulator - - - 0.000000000000000000000000000008646 123.0
HKD1_k127_1962128_36 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000001568 126.0
HKD1_k127_1962128_37 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000000000007994 130.0
HKD1_k127_1962128_38 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000005188 111.0
HKD1_k127_1962128_39 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000357 119.0
HKD1_k127_1962128_4 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 597.0
HKD1_k127_1962128_40 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000005793 113.0
HKD1_k127_1962128_41 Molybdopterin converting factor, small subunit K03636 - - 0.000000000000000000003628 95.0
HKD1_k127_1962128_42 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000008201 81.0
HKD1_k127_1962128_43 COG1522 Transcriptional regulators - - - 0.00005055 55.0
HKD1_k127_1962128_44 membrane - - - 0.0003471 53.0
HKD1_k127_1962128_5 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 502.0
HKD1_k127_1962128_6 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 497.0
HKD1_k127_1962128_7 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 465.0
HKD1_k127_1962128_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 437.0
HKD1_k127_1962128_9 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 419.0
HKD1_k127_1974566_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00822,K00833 - 2.6.1.18,2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 465.0
HKD1_k127_1974566_1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 419.0
HKD1_k127_1974566_10 CoA-transferase family III K18702 - 2.8.3.19 0.0000000000000000000003573 104.0
HKD1_k127_1974566_2 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 355.0
HKD1_k127_1974566_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 321.0
HKD1_k127_1974566_4 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005644 282.0
HKD1_k127_1974566_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000002743 273.0
HKD1_k127_1974566_6 PFAM binding-protein-dependent transport systems inner membrane component K10237 - - 0.000000000000000000000000000000000000000000000000000000002155 212.0
HKD1_k127_1974566_7 helix_turn_helix isocitrate lyase regulation K13641 - - 0.00000000000000000000000000000000000000000000003666 191.0
HKD1_k127_1974566_8 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000008177 177.0
HKD1_k127_1974566_9 ABC-type sugar transport system periplasmic component - - - 0.0000000000000000000000008234 121.0
HKD1_k127_199670_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 350.0
HKD1_k127_199670_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 334.0
HKD1_k127_199670_10 involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000007312 175.0
HKD1_k127_199670_11 Glycosyl transferase, family 2 - - - 0.000000000000000000000000001725 131.0
HKD1_k127_199670_12 Tetratricopeptide repeat - - - 0.000000000000000000000002311 121.0
HKD1_k127_199670_13 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000000000000000734 117.0
HKD1_k127_199670_14 PFAM lipolytic protein G-D-S-L family - - - 0.0000000000000000806 92.0
HKD1_k127_199670_15 lipolytic protein G-D-S-L family - - - 0.000000000002037 79.0
HKD1_k127_199670_16 Uncharacterised nucleotidyltransferase - - - 0.00000008363 65.0
HKD1_k127_199670_17 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.000000577 61.0
HKD1_k127_199670_18 Putative beta-barrel porin 2 - - - 0.0006232 53.0
HKD1_k127_199670_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000826 290.0
HKD1_k127_199670_3 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000009712 248.0
HKD1_k127_199670_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000006763 252.0
HKD1_k127_199670_5 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000647 229.0
HKD1_k127_199670_6 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000005625 218.0
HKD1_k127_199670_7 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000001965 196.0
HKD1_k127_199670_8 Glycosyl transferase, family 2 K20444 - - 0.00000000000000000000000000000000000000000000000001322 204.0
HKD1_k127_199670_9 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000001568 203.0
HKD1_k127_2057033_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 614.0
HKD1_k127_2057033_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 539.0
HKD1_k127_2057033_2 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 GO:0003674,GO:0005215,GO:0005451,GO:0005488,GO:0005543,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006875,GO:0006883,GO:0006885,GO:0006950,GO:0006970,GO:0008150,GO:0008289,GO:0008324,GO:0009628,GO:0009651,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0035725,GO:0042592,GO:0043157,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051453,GO:0055065,GO:0055067,GO:0055078,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1901611,GO:1901612,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 423.0
HKD1_k127_2057033_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008119 441.0
HKD1_k127_2057033_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000004913 186.0
HKD1_k127_2057684_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 2.536e-314 991.0
HKD1_k127_2057684_1 Enoyl-CoA hydratase/isomerase - - - 6.933e-238 749.0
HKD1_k127_2057684_2 benzoyl-CoA oxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 485.0
HKD1_k127_2057684_3 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 389.0
HKD1_k127_2057684_4 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001122 239.0
HKD1_k127_2065904_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 2.489e-264 837.0
HKD1_k127_2065904_1 Domain of unknown function (DUF4070) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 471.0
HKD1_k127_2065904_2 5'-nucleotidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 368.0
HKD1_k127_2065904_3 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 289.0
HKD1_k127_2065904_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001261 249.0
HKD1_k127_2065904_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000004071 221.0
HKD1_k127_2065904_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000001036 193.0
HKD1_k127_2065904_7 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000001681 174.0
HKD1_k127_2065904_8 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000003366 101.0
HKD1_k127_2065904_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000001205 71.0
HKD1_k127_2090614_0 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 545.0
HKD1_k127_2090614_1 AAA ATPase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 514.0
HKD1_k127_2090614_10 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007146 266.0
HKD1_k127_2090614_11 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000002957 239.0
HKD1_k127_2090614_12 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000007452 242.0
HKD1_k127_2090614_13 Acetyltransferase (GNAT) domain K03817 - - 0.0000000000000000000000000000000000000000000000000000008401 198.0
HKD1_k127_2090614_14 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000005215 192.0
HKD1_k127_2090614_15 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000002102 178.0
HKD1_k127_2090614_16 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000001834 173.0
HKD1_k127_2090614_17 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000001883 166.0
HKD1_k127_2090614_18 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000002256 137.0
HKD1_k127_2090614_19 methyltransferase - - - 0.0000000000000000000000000006664 129.0
HKD1_k127_2090614_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 492.0
HKD1_k127_2090614_20 phosphonoacetaldehyde hydrolase activity K01091 - 3.1.3.18 0.0000000000000000000000001094 124.0
HKD1_k127_2090614_21 endonuclease III K07457 - - 0.0000000000000000000003453 113.0
HKD1_k127_2090614_22 - - - - 0.0000000009197 69.0
HKD1_k127_2090614_23 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000003269 68.0
HKD1_k127_2090614_24 Tetratricopeptide TPR_2 repeat protein - - - 0.0000002352 63.0
HKD1_k127_2090614_25 C-terminal, D2-small domain, of ClpB protein - - - 0.000008239 60.0
HKD1_k127_2090614_26 Tetratricopeptide repeat - - - 0.00003165 58.0
HKD1_k127_2090614_27 PFAM NMT1 THI5 like domain protein K02051 - - 0.00008166 55.0
HKD1_k127_2090614_28 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0005784 51.0
HKD1_k127_2090614_3 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 428.0
HKD1_k127_2090614_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 426.0
HKD1_k127_2090614_5 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 361.0
HKD1_k127_2090614_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 354.0
HKD1_k127_2090614_7 Glycosyltransferase family 28 N-terminal domain K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 346.0
HKD1_k127_2090614_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 321.0
HKD1_k127_2090614_9 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005806 288.0
HKD1_k127_2104819_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0 1108.0
HKD1_k127_2104819_1 Hydantoinase/oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 1.374e-210 680.0
HKD1_k127_2104819_2 Hydantoinase B/oxoprolinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 594.0
HKD1_k127_2104819_3 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 334.0
HKD1_k127_2104819_4 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) K03740 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 295.0
HKD1_k127_2104819_5 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000003244 235.0
HKD1_k127_2104819_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000008937 222.0
HKD1_k127_2104819_7 Osmosensitive K+ channel His kinase sensor domain K07646 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 2.7.13.3 0.0000000003346 70.0
HKD1_k127_2104819_9 Belongs to the universal stress protein A family - - - 0.00004461 47.0
HKD1_k127_2136438_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 418.0
HKD1_k127_2136438_1 ornithine cyclodeaminase activity K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 358.0
HKD1_k127_2136438_2 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000475 219.0
HKD1_k127_2136438_3 Chromate resistance - - - 0.000000000000000000000000000000000000000000000000008236 190.0
HKD1_k127_2136438_4 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K15942 - 2.1.1.288 0.000000000000000000000000000000000000000006961 161.0
HKD1_k127_2136438_5 Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000005891 77.0
HKD1_k127_2136438_6 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.00000000003726 68.0
HKD1_k127_2136438_7 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000002177 61.0
HKD1_k127_2139823_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 1.6e-322 1011.0
HKD1_k127_2139823_1 His Kinase A (phosphoacceptor) domain - - - 2.7e-321 1017.0
HKD1_k127_2139823_10 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 441.0
HKD1_k127_2139823_11 CoA-transferase family III K07749 GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0047369 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 438.0
HKD1_k127_2139823_12 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 441.0
HKD1_k127_2139823_13 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 436.0
HKD1_k127_2139823_14 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 414.0
HKD1_k127_2139823_15 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K19189 - 1.14.13.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 406.0
HKD1_k127_2139823_16 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 389.0
HKD1_k127_2139823_17 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 370.0
HKD1_k127_2139823_18 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 392.0
HKD1_k127_2139823_19 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 376.0
HKD1_k127_2139823_2 Bacterial protein of unknown function (DUF853) K06915 - - 6.536e-251 781.0
HKD1_k127_2139823_20 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 328.0
HKD1_k127_2139823_21 cystathionine gamma-synthase K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 328.0
HKD1_k127_2139823_22 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 319.0
HKD1_k127_2139823_23 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 317.0
HKD1_k127_2139823_24 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 303.0
HKD1_k127_2139823_25 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 310.0
HKD1_k127_2139823_26 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 295.0
HKD1_k127_2139823_27 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002005 303.0
HKD1_k127_2139823_28 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007391 271.0
HKD1_k127_2139823_29 Enoyl-CoA hydratase/isomerase K07546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008997 262.0
HKD1_k127_2139823_3 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.573e-215 686.0
HKD1_k127_2139823_30 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002364 256.0
HKD1_k127_2139823_31 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000646 266.0
HKD1_k127_2139823_32 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000003697 224.0
HKD1_k127_2139823_33 Glucose dehydrogenase C-terminus K00008,K00060 - 1.1.1.103,1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000001166 226.0
HKD1_k127_2139823_34 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000009958 213.0
HKD1_k127_2139823_35 hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000001197 231.0
HKD1_k127_2139823_36 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000001944 223.0
HKD1_k127_2139823_37 Membrane - - - 0.00000000000000000000000000000000000000000000000000000009661 222.0
HKD1_k127_2139823_38 acid phosphatase - - - 0.0000000000000000000000000000000000000000000000000000001019 218.0
HKD1_k127_2139823_39 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000863 217.0
HKD1_k127_2139823_4 protein conserved in bacteria K07793 - - 2.152e-206 653.0
HKD1_k127_2139823_40 NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000002729 194.0
HKD1_k127_2139823_41 Fumarylacetoacetate (FAA) hydrolase family K02554 - 4.2.1.80 0.00000000000000000000000000000000000000000000000004354 189.0
HKD1_k127_2139823_42 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000001249 203.0
HKD1_k127_2139823_43 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000008018 193.0
HKD1_k127_2139823_44 cheY-homologous receiver domain K11443 - - 0.000000000000000000000000000000000000000000004429 180.0
HKD1_k127_2139823_45 FCD K05799 - - 0.00000000000000000000000000000000000000000001488 181.0
HKD1_k127_2139823_46 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000000000000272 156.0
HKD1_k127_2139823_47 NUDIX domain - - - 0.0000000000000000000000000000000000000001608 157.0
HKD1_k127_2139823_48 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000007979 149.0
HKD1_k127_2139823_49 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000006031 151.0
HKD1_k127_2139823_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 505.0
HKD1_k127_2139823_50 Zn peptidase - - - 0.00000000000000000000000000000000001625 157.0
HKD1_k127_2139823_51 Phosphate acetyl butaryl transferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000001281 148.0
HKD1_k127_2139823_52 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000008562 130.0
HKD1_k127_2139823_53 hydrolase - - - 0.000000000000000000000000000007768 128.0
HKD1_k127_2139823_54 PFAM PHA accumulation regulator DNA-binding protein - - - 0.0000000000000000000000000005753 122.0
HKD1_k127_2139823_55 -acetyltransferase - - - 0.000000000000000000000000002537 117.0
HKD1_k127_2139823_56 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000001244 121.0
HKD1_k127_2139823_57 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000004426 120.0
HKD1_k127_2139823_58 Smr domain - - - 0.000000000000000000000002794 109.0
HKD1_k127_2139823_59 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000003668 120.0
HKD1_k127_2139823_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 527.0
HKD1_k127_2139823_60 Sterol carrier protein - - - 0.000000000000000000001711 103.0
HKD1_k127_2139823_61 - - - - 0.000000000000792 77.0
HKD1_k127_2139823_62 polyhydroxyalkanoic acid synthase, PhaR subunit - - - 0.00000000001774 77.0
HKD1_k127_2139823_63 ATP-dependent Clp protease adaptor protein ClpS - - - 0.00000003516 66.0
HKD1_k127_2139823_64 Protein of unknown function (DUF1318) - - - 0.00000006812 64.0
HKD1_k127_2139823_65 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0002558 55.0
HKD1_k127_2139823_7 Domain of unknown function (DUF4445) K04755,K08952,K08953,K08954 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 502.0
HKD1_k127_2139823_8 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 486.0
HKD1_k127_2139823_9 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005657 484.0
HKD1_k127_2147487_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 9.267e-312 965.0
HKD1_k127_2147487_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 2.012e-218 722.0
HKD1_k127_2147487_10 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 442.0
HKD1_k127_2147487_11 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 441.0
HKD1_k127_2147487_12 PFAM Dehydrogenase, E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 403.0
HKD1_k127_2147487_13 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007939 419.0
HKD1_k127_2147487_14 ABC transporter K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 409.0
HKD1_k127_2147487_15 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 401.0
HKD1_k127_2147487_16 KR domain K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 379.0
HKD1_k127_2147487_17 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 401.0
HKD1_k127_2147487_18 ABC transporter K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 383.0
HKD1_k127_2147487_19 ABC transporter K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 377.0
HKD1_k127_2147487_2 Dehydratase family - - - 4.332e-213 677.0
HKD1_k127_2147487_20 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 360.0
HKD1_k127_2147487_21 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 373.0
HKD1_k127_2147487_22 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 364.0
HKD1_k127_2147487_23 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 364.0
HKD1_k127_2147487_24 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 355.0
HKD1_k127_2147487_25 TIGRFAM stage V sporulation protein E, cell division protein FtsW K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 373.0
HKD1_k127_2147487_26 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 368.0
HKD1_k127_2147487_27 Histidyl-tRNA synthetase K00765,K01892,K02502 - 2.4.2.17,6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 355.0
HKD1_k127_2147487_28 Peptidase S15 K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 346.0
HKD1_k127_2147487_29 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 307.0
HKD1_k127_2147487_3 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 568.0
HKD1_k127_2147487_30 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 295.0
HKD1_k127_2147487_31 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000178 290.0
HKD1_k127_2147487_32 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002237 311.0
HKD1_k127_2147487_33 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002886 287.0
HKD1_k127_2147487_34 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000002226 274.0
HKD1_k127_2147487_35 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003595 259.0
HKD1_k127_2147487_36 coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000002141 257.0
HKD1_k127_2147487_37 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000351 248.0
HKD1_k127_2147487_38 transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000002216 236.0
HKD1_k127_2147487_39 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000001248 239.0
HKD1_k127_2147487_4 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 551.0
HKD1_k127_2147487_40 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000002268 222.0
HKD1_k127_2147487_41 cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000002579 216.0
HKD1_k127_2147487_42 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000005167 206.0
HKD1_k127_2147487_43 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000163 202.0
HKD1_k127_2147487_44 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000002566 160.0
HKD1_k127_2147487_45 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000001462 151.0
HKD1_k127_2147487_46 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000001057 145.0
HKD1_k127_2147487_47 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000000005906 142.0
HKD1_k127_2147487_48 carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000001717 130.0
HKD1_k127_2147487_49 YGGT family K02221 - - 0.000000000000000000000000000005797 121.0
HKD1_k127_2147487_5 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 492.0
HKD1_k127_2147487_50 - - - - 0.000000000000000000000000005331 115.0
HKD1_k127_2147487_51 PFAM DivIVA family protein K04074 - - 0.00000000000000000000166 101.0
HKD1_k127_2147487_52 Transglycosylase associated protein - - - 0.0000000000000000008226 89.0
HKD1_k127_2147487_53 Essential cell division protein K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000005233 86.0
HKD1_k127_2147487_54 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000002694 76.0
HKD1_k127_2147487_55 NMT1-like family K02051 - - 0.0000000004623 71.0
HKD1_k127_2147487_56 DUF167 K09131 - - 0.00000005592 58.0
HKD1_k127_2147487_57 Protein of unknown function (DUF861) - - - 0.00009782 53.0
HKD1_k127_2147487_58 Domain of unknown function (DUF4864) - - - 0.0001301 54.0
HKD1_k127_2147487_59 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0004723 52.0
HKD1_k127_2147487_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 478.0
HKD1_k127_2147487_60 ligase activity - - - 0.0004861 48.0
HKD1_k127_2147487_7 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 458.0
HKD1_k127_2147487_8 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 453.0
HKD1_k127_2147487_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 453.0
HKD1_k127_2159428_0 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 607.0
HKD1_k127_2159428_1 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 566.0
HKD1_k127_2159428_10 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000112 291.0
HKD1_k127_2159428_11 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000549 250.0
HKD1_k127_2159428_12 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000001189 230.0
HKD1_k127_2159428_13 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000002476 237.0
HKD1_k127_2159428_14 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000001335 231.0
HKD1_k127_2159428_15 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000004668 191.0
HKD1_k127_2159428_16 HD-GYP domain - - - 0.000000000000000000000000000000000000000000031 168.0
HKD1_k127_2159428_17 Thioredoxin - - - 0.000000000000000000000000000000000000002597 154.0
HKD1_k127_2159428_18 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000002335 160.0
HKD1_k127_2159428_19 YXWGXW repeat (2 copies) - - - 0.0000000000000004202 91.0
HKD1_k127_2159428_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 487.0
HKD1_k127_2159428_20 - - - - 0.00000000002919 76.0
HKD1_k127_2159428_21 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000695 64.0
HKD1_k127_2159428_22 - - - - 0.0000003482 61.0
HKD1_k127_2159428_3 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 460.0
HKD1_k127_2159428_4 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 455.0
HKD1_k127_2159428_5 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 451.0
HKD1_k127_2159428_6 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 368.0
HKD1_k127_2159428_7 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 322.0
HKD1_k127_2159428_8 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 326.0
HKD1_k127_2159428_9 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 314.0
HKD1_k127_2199607_0 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 429.0
HKD1_k127_2199607_1 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000709 273.0
HKD1_k127_2199607_2 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000004966 129.0
HKD1_k127_2199607_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000009249 127.0
HKD1_k127_2199607_4 PFAM binding-protein-dependent transport systems inner membrane component K02033,K15581 - - 0.000000000000000001281 87.0
HKD1_k127_2199607_5 - - - - 0.000000000000000002103 93.0
HKD1_k127_2199607_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000002453 82.0
HKD1_k127_2199607_7 Domain of unknown function (DUF4976) - - - 0.000000002331 66.0
HKD1_k127_2199607_8 polyketide synthase - - - 0.000002214 61.0
HKD1_k127_2199607_9 Thioredoxin-like - - - 0.000002907 61.0
HKD1_k127_2220901_0 Large extracellular alpha-helical protein K06894 - - 0.0 1794.0
HKD1_k127_2220901_1 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 0.0 1664.0
HKD1_k127_2220901_10 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 559.0
HKD1_k127_2220901_100 Protein of unknown function (DUF3574) - - - 0.00000000000000000000000000453 117.0
HKD1_k127_2220901_101 Protein conserved in bacteria - - - 0.0000000000000000000000000614 109.0
HKD1_k127_2220901_102 Gram-negative-bacterium-type cell wall biogenesis - - - 0.0000000000000000000000001175 125.0
HKD1_k127_2220901_103 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000001743 115.0
HKD1_k127_2220901_104 Domain of unknown function (DUF1772) - - - 0.00000000000000000000009957 103.0
HKD1_k127_2220901_105 protein, possibly involved in aromatic compounds catabolism K02614 - - 0.00000000000000000005777 105.0
HKD1_k127_2220901_106 Periplasmic binding protein domain K01999 - - 0.000000000000000007384 90.0
HKD1_k127_2220901_107 phosphorelay sensor kinase activity - - - 0.0000000000000004044 90.0
HKD1_k127_2220901_108 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000002508 87.0
HKD1_k127_2220901_109 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.00000000000000266 90.0
HKD1_k127_2220901_11 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 583.0
HKD1_k127_2220901_110 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000003715 87.0
HKD1_k127_2220901_111 PFAM EamA-like transporter family - - - 0.00000000000005262 82.0
HKD1_k127_2220901_112 Redoxin K03564 - 1.11.1.15 0.000000000003076 72.0
HKD1_k127_2220901_113 DinB superfamily - - - 0.000000000007061 72.0
HKD1_k127_2220901_114 - - - - 0.000000000008922 79.0
HKD1_k127_2220901_115 Vitamin B12 dependent methionine synthase activation - - - 0.00000000003008 73.0
HKD1_k127_2220901_116 protein conserved in bacteria K22129 - 2.7.1.219,2.7.1.220 0.0000000003117 68.0
HKD1_k127_2220901_117 PFAM YCII-related K09780 - - 0.0000003043 59.0
HKD1_k127_2220901_119 Antibiotic biosynthesis monooxygenase - - - 0.000002119 53.0
HKD1_k127_2220901_12 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 544.0
HKD1_k127_2220901_120 Glycosyl transferase 4-like - - - 0.00000463 59.0
HKD1_k127_2220901_121 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00002234 59.0
HKD1_k127_2220901_122 Pfam:Methyltransf_26 - - - 0.0002875 51.0
HKD1_k127_2220901_123 Phosphorylase superfamily K00772 - 2.4.2.28 0.0005938 52.0
HKD1_k127_2220901_13 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 507.0
HKD1_k127_2220901_14 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 514.0
HKD1_k127_2220901_15 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 519.0
HKD1_k127_2220901_16 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 501.0
HKD1_k127_2220901_17 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 471.0
HKD1_k127_2220901_18 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 492.0
HKD1_k127_2220901_19 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 440.0
HKD1_k127_2220901_2 Belongs to the IlvD Edd family K22396 - 4.2.1.82 1.953e-305 971.0
HKD1_k127_2220901_20 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 438.0
HKD1_k127_2220901_21 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 434.0
HKD1_k127_2220901_22 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 437.0
HKD1_k127_2220901_23 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 417.0
HKD1_k127_2220901_24 PFAM AMP-dependent synthetase K12422 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 417.0
HKD1_k127_2220901_25 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 402.0
HKD1_k127_2220901_26 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 400.0
HKD1_k127_2220901_27 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 392.0
HKD1_k127_2220901_28 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 389.0
HKD1_k127_2220901_29 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 378.0
HKD1_k127_2220901_3 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 9.339e-264 830.0
HKD1_k127_2220901_30 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 378.0
HKD1_k127_2220901_31 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 362.0
HKD1_k127_2220901_32 PFAM Transketolase central region K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 371.0
HKD1_k127_2220901_33 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 359.0
HKD1_k127_2220901_34 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 347.0
HKD1_k127_2220901_35 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 355.0
HKD1_k127_2220901_36 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 355.0
HKD1_k127_2220901_37 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 339.0
HKD1_k127_2220901_38 exonuclease activity K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 364.0
HKD1_k127_2220901_39 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 328.0
HKD1_k127_2220901_4 FtsX-like permease family K02004 - - 6.2e-210 690.0
HKD1_k127_2220901_40 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 345.0
HKD1_k127_2220901_41 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009436,GO:0009442,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042737,GO:0043436,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046700,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 321.0
HKD1_k127_2220901_42 Peptide ABC transporter permease K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 321.0
HKD1_k127_2220901_43 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 312.0
HKD1_k127_2220901_44 PFAM Alcohol dehydrogenase, zinc-binding K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 310.0
HKD1_k127_2220901_45 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 329.0
HKD1_k127_2220901_46 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 302.0
HKD1_k127_2220901_47 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 305.0
HKD1_k127_2220901_48 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 311.0
HKD1_k127_2220901_49 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 316.0
HKD1_k127_2220901_5 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 612.0
HKD1_k127_2220901_50 Alpha beta hydrolase K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 308.0
HKD1_k127_2220901_51 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 295.0
HKD1_k127_2220901_52 phosphotriesterase related K07048 GO:0008150,GO:0009888,GO:0009987,GO:0030154,GO:0030855,GO:0032502,GO:0048856,GO:0048869,GO:0060429 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 297.0
HKD1_k127_2220901_53 COG0477 Permeases of the major facilitator superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002288 292.0
HKD1_k127_2220901_54 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006741 301.0
HKD1_k127_2220901_55 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002595 274.0
HKD1_k127_2220901_56 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002601 284.0
HKD1_k127_2220901_57 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004163 256.0
HKD1_k127_2220901_58 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000002092 270.0
HKD1_k127_2220901_59 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001509 255.0
HKD1_k127_2220901_6 penicillin-binding protein K05367 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 629.0
HKD1_k127_2220901_60 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001311 259.0
HKD1_k127_2220901_61 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000587 246.0
HKD1_k127_2220901_62 myo-inosose-2 dehydratase activity K00457,K06606 - 1.13.11.27,5.3.99.11 0.00000000000000000000000000000000000000000000000000000000000000002804 246.0
HKD1_k127_2220901_63 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000004178 241.0
HKD1_k127_2220901_64 Acetohydroxy acid isomeroreductase, NADPH-binding domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000001232 230.0
HKD1_k127_2220901_65 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000005405 227.0
HKD1_k127_2220901_66 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000005622 220.0
HKD1_k127_2220901_67 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.00000000000000000000000000000000000000000000000000000001463 216.0
HKD1_k127_2220901_68 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050,K15554 - - 0.00000000000000000000000000000000000000000000000000000004083 206.0
HKD1_k127_2220901_69 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000001504 205.0
HKD1_k127_2220901_7 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006327 585.0
HKD1_k127_2220901_71 short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000005947 197.0
HKD1_k127_2220901_72 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000001346 199.0
HKD1_k127_2220901_73 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008874,GO:0008875,GO:0016491,GO:0016614,GO:0016616,GO:0036094,GO:0042802,GO:0042803,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.1.1.69 0.000000000000000000000000000000000000000000000000002377 194.0
HKD1_k127_2220901_74 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000003464 190.0
HKD1_k127_2220901_75 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000001178 199.0
HKD1_k127_2220901_76 4Fe-4S dicluster domain K00196,K05796 - - 0.00000000000000000000000000000000000000000000000004599 183.0
HKD1_k127_2220901_77 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000003288 201.0
HKD1_k127_2220901_78 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000003315 180.0
HKD1_k127_2220901_79 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.000000000000000000000000000000000000000000001508 173.0
HKD1_k127_2220901_8 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 573.0
HKD1_k127_2220901_80 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000003334 183.0
HKD1_k127_2220901_81 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000002016 166.0
HKD1_k127_2220901_82 GAF domain - - - 0.0000000000000000000000000000000000000000001778 185.0
HKD1_k127_2220901_83 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000006223 181.0
HKD1_k127_2220901_84 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000001038 155.0
HKD1_k127_2220901_85 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000001359 178.0
HKD1_k127_2220901_86 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.0000000000000000000000000000000000000002241 167.0
HKD1_k127_2220901_87 - - - - 0.000000000000000000000000000000000002081 152.0
HKD1_k127_2220901_88 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000003147 139.0
HKD1_k127_2220901_89 Amidohydrolase family - - - 0.000000000000000000000000000000000008423 154.0
HKD1_k127_2220901_9 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 555.0
HKD1_k127_2220901_90 Thioesterase family - - - 0.0000000000000000000000000000000009834 140.0
HKD1_k127_2220901_91 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000001571 132.0
HKD1_k127_2220901_92 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000729 131.0
HKD1_k127_2220901_93 GYD domain - - - 0.0000000000000000000000000000001722 126.0
HKD1_k127_2220901_94 Cupin domain - - - 0.000000000000000000000000000008555 126.0
HKD1_k127_2220901_95 Anti-sigma-K factor rskA - - - 0.00000000000000000000000000001077 134.0
HKD1_k127_2220901_96 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000005318 133.0
HKD1_k127_2220901_97 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000000000000008673 122.0
HKD1_k127_2220901_98 Thioesterase superfamily - - - 0.000000000000000000000000001859 117.0
HKD1_k127_2220901_99 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000002663 130.0
HKD1_k127_2287464_0 macromolecule localization K01421,K01992,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 306.0
HKD1_k127_2287464_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 300.0
HKD1_k127_2287464_2 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 306.0
HKD1_k127_2287464_3 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000294 285.0
HKD1_k127_2287464_4 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000009591 261.0
HKD1_k127_2287464_5 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000002358 225.0
HKD1_k127_2287464_6 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000009679 224.0
HKD1_k127_2288840_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.452e-226 732.0
HKD1_k127_2288840_1 Amidase K01426,K02433 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 512.0
HKD1_k127_2288840_10 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 406.0
HKD1_k127_2288840_11 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 403.0
HKD1_k127_2288840_12 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 390.0
HKD1_k127_2288840_13 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 381.0
HKD1_k127_2288840_14 PFAM MltA domain protein K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 353.0
HKD1_k127_2288840_15 PFAM ABC transporter K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 339.0
HKD1_k127_2288840_16 COG5008 Tfp pilus assembly protein, ATPase PilU K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 327.0
HKD1_k127_2288840_17 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 338.0
HKD1_k127_2288840_18 PFAM Major Facilitator Superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 315.0
HKD1_k127_2288840_19 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 299.0
HKD1_k127_2288840_2 Binding-protein-dependent transport system inner membrane component K02033 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 485.0
HKD1_k127_2288840_20 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 299.0
HKD1_k127_2288840_21 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002361 298.0
HKD1_k127_2288840_22 Histidine kinase K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000188 283.0
HKD1_k127_2288840_23 Glycoside hydrolase family 3 domain protein K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000002408 232.0
HKD1_k127_2288840_24 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.00000000000000000000000000000000000000000000000000000003249 211.0
HKD1_k127_2288840_25 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000001031 202.0
HKD1_k127_2288840_26 bis(5'-adenosyl)-triphosphatase activity - - - 0.00000000000000000000000000000000000000000000003622 173.0
HKD1_k127_2288840_27 YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000000000000000000000000000001133 170.0
HKD1_k127_2288840_28 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000002446 186.0
HKD1_k127_2288840_29 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000004801 159.0
HKD1_k127_2288840_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 460.0
HKD1_k127_2288840_30 EamA-like transporter family - - - 0.000000000000000000000000000000000000000486 160.0
HKD1_k127_2288840_31 3-hydroxyanthranilate 3,4-dioxygenase activity - - - 0.000000000000000000000000000000000001535 156.0
HKD1_k127_2288840_32 General secretory system II protein E domain protein K02652 - - 0.0000000000000000000000000000000002351 154.0
HKD1_k127_2288840_33 HD domain - - - 0.0000000000000000000000002941 124.0
HKD1_k127_2288840_34 Response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000001763 100.0
HKD1_k127_2288840_35 Domain of unknown function (DUF4203) - - - 0.000000000000000008342 98.0
HKD1_k127_2288840_36 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000005731 75.0
HKD1_k127_2288840_4 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 421.0
HKD1_k127_2288840_5 COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 420.0
HKD1_k127_2288840_6 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 445.0
HKD1_k127_2288840_7 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 431.0
HKD1_k127_2288840_8 ATPases associated with a variety of cellular activities K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 407.0
HKD1_k127_2288840_9 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 422.0
HKD1_k127_2292077_0 SNF2 family N-terminal domain - - - 2.12e-305 968.0
HKD1_k127_2292077_1 Proton-conducting membrane transporter K12137,K15828 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 628.0
HKD1_k127_2292077_10 Proton-conducting membrane transporter K12141 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 467.0
HKD1_k127_2292077_11 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 440.0
HKD1_k127_2292077_12 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 411.0
HKD1_k127_2292077_13 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 422.0
HKD1_k127_2292077_14 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 407.0
HKD1_k127_2292077_15 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 392.0
HKD1_k127_2292077_16 NADH dehydrogenase K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 387.0
HKD1_k127_2292077_17 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 357.0
HKD1_k127_2292077_18 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 350.0
HKD1_k127_2292077_19 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 343.0
HKD1_k127_2292077_2 NADH dehydrogenase (ubiquinone) activity K14089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 606.0
HKD1_k127_2292077_20 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 345.0
HKD1_k127_2292077_21 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 341.0
HKD1_k127_2292077_22 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 357.0
HKD1_k127_2292077_23 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 331.0
HKD1_k127_2292077_24 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 342.0
HKD1_k127_2292077_25 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 352.0
HKD1_k127_2292077_27 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 297.0
HKD1_k127_2292077_28 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002453 287.0
HKD1_k127_2292077_29 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003632 288.0
HKD1_k127_2292077_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 571.0
HKD1_k127_2292077_30 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007368 304.0
HKD1_k127_2292077_31 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000111 277.0
HKD1_k127_2292077_32 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003198 295.0
HKD1_k127_2292077_33 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001418 278.0
HKD1_k127_2292077_34 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002319 287.0
HKD1_k127_2292077_35 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002895 270.0
HKD1_k127_2292077_36 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000008282 264.0
HKD1_k127_2292077_37 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000001421 256.0
HKD1_k127_2292077_38 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000167 244.0
HKD1_k127_2292077_39 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000003994 244.0
HKD1_k127_2292077_4 acyl-coa dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 569.0
HKD1_k127_2292077_40 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000001178 231.0
HKD1_k127_2292077_41 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000586 232.0
HKD1_k127_2292077_42 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000005758 220.0
HKD1_k127_2292077_43 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000006318 228.0
HKD1_k127_2292077_44 Transport permease protein K09688,K09690 - - 0.00000000000000000000000000000000000000000000000000000000000008262 222.0
HKD1_k127_2292077_45 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000002729 228.0
HKD1_k127_2292077_46 PFAM Methyltransferase domain K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000000000000000000003002 243.0
HKD1_k127_2292077_48 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000351 203.0
HKD1_k127_2292077_49 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000003382 192.0
HKD1_k127_2292077_5 Coenzyme A transferase K01026 - 2.8.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 570.0
HKD1_k127_2292077_50 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000001373 186.0
HKD1_k127_2292077_51 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000001458 194.0
HKD1_k127_2292077_52 Choline/ethanolamine kinase - - - 0.0000000000000000000000000000000000000000000003407 181.0
HKD1_k127_2292077_53 - - - - 0.0000000000000000000000000000000000000000001709 184.0
HKD1_k127_2292077_54 methyltransferase K05928 - 2.1.1.95 0.000000000000000000000000000000000000000003871 166.0
HKD1_k127_2292077_55 Hydrogenase 4 membrane K12140 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000005144 163.0
HKD1_k127_2292077_56 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000004857 162.0
HKD1_k127_2292077_57 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000004832 151.0
HKD1_k127_2292077_58 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.00000000000000000000000000348 119.0
HKD1_k127_2292077_59 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000008199 108.0
HKD1_k127_2292077_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 574.0
HKD1_k127_2292077_60 PFAM EamA-like transporter family - - - 0.0000000000000000000001185 112.0
HKD1_k127_2292077_61 glycosyl transferase group 1 - - - 0.000000000000000000003207 109.0
HKD1_k127_2292077_62 Helix-turn-helix domain - - - 0.0000000000000000001386 92.0
HKD1_k127_2292077_63 Repressor involved in choline regulation of the bet genes K02167 - - 0.0000000000000000001679 98.0
HKD1_k127_2292077_64 peptidyl-tyrosine sulfation - - - 0.000000000003094 81.0
HKD1_k127_2292077_65 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000001874 73.0
HKD1_k127_2292077_66 mttA/Hcf106 family K03116 - - 0.0000000194 59.0
HKD1_k127_2292077_67 FAD dependent oxidoreductase - - - 0.00000002794 56.0
HKD1_k127_2292077_68 DoxX K15977 - - 0.0000008996 57.0
HKD1_k127_2292077_69 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000001704 52.0
HKD1_k127_2292077_7 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 530.0
HKD1_k127_2292077_71 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00001671 57.0
HKD1_k127_2292077_72 phosphatase activity K01560,K07025 - 3.8.1.2 0.0001088 53.0
HKD1_k127_2292077_73 Glycosyl hydrolase family 65, N-terminal domain - - - 0.0001562 54.0
HKD1_k127_2292077_8 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 496.0
HKD1_k127_2292077_9 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 491.0
HKD1_k127_2320310_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 3.317e-235 761.0
HKD1_k127_2320310_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.292e-223 713.0
HKD1_k127_2320310_10 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 400.0
HKD1_k127_2320310_11 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 401.0
HKD1_k127_2320310_12 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 377.0
HKD1_k127_2320310_13 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 373.0
HKD1_k127_2320310_14 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 333.0
HKD1_k127_2320310_15 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 333.0
HKD1_k127_2320310_16 SMART PDZ DHR GLGF domain protein K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 336.0
HKD1_k127_2320310_17 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 324.0
HKD1_k127_2320310_18 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 333.0
HKD1_k127_2320310_19 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 325.0
HKD1_k127_2320310_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.389e-194 621.0
HKD1_k127_2320310_20 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 306.0
HKD1_k127_2320310_21 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001011 286.0
HKD1_k127_2320310_22 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001129 292.0
HKD1_k127_2320310_23 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004993 280.0
HKD1_k127_2320310_24 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003166 263.0
HKD1_k127_2320310_25 of the double-stranded beta helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001855 249.0
HKD1_k127_2320310_26 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000001067 254.0
HKD1_k127_2320310_27 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000007102 245.0
HKD1_k127_2320310_28 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000514 241.0
HKD1_k127_2320310_29 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000003967 222.0
HKD1_k127_2320310_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 607.0
HKD1_k127_2320310_30 MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000001011 238.0
HKD1_k127_2320310_31 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000112 224.0
HKD1_k127_2320310_32 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000263 229.0
HKD1_k127_2320310_33 thiamine-containing compound biosynthetic process K02051,K15553 - - 0.000000000000000000000000000000000000000000000000000000004927 225.0
HKD1_k127_2320310_34 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000001014 203.0
HKD1_k127_2320310_35 photosynthesis - - - 0.000000000000000000000000000000000000000000000000004474 190.0
HKD1_k127_2320310_36 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000009373 185.0
HKD1_k127_2320310_37 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000005636 177.0
HKD1_k127_2320310_38 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000003799 191.0
HKD1_k127_2320310_39 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000002406 171.0
HKD1_k127_2320310_4 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 541.0
HKD1_k127_2320310_40 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000004272 168.0
HKD1_k127_2320310_41 B12 binding domain - - - 0.00000000000000000000000000000000000000001143 163.0
HKD1_k127_2320310_42 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000173 170.0
HKD1_k127_2320310_43 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000004993 122.0
HKD1_k127_2320310_44 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000001253 118.0
HKD1_k127_2320310_45 Ferredoxin - - - 0.0000000000000000001414 104.0
HKD1_k127_2320310_46 Protein of unknown function (DUF448) K07742 - - 0.000000000008203 77.0
HKD1_k127_2320310_47 Methyltransferase domain - - - 0.00001284 57.0
HKD1_k127_2320310_48 PFAM Cupin 2, conserved barrel domain protein - - - 0.00003749 51.0
HKD1_k127_2320310_49 Zn-ribbon protein possibly nucleic acid-binding - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0003378 54.0
HKD1_k127_2320310_5 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 471.0
HKD1_k127_2320310_6 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 450.0
HKD1_k127_2320310_7 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 449.0
HKD1_k127_2320310_8 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 412.0
HKD1_k127_2320310_9 CoA-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 422.0
HKD1_k127_2403792_0 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000006208 165.0
HKD1_k127_2403792_1 IMP dehydrogenase activity K02902 - - 0.00000000000000000000000000000000000006687 147.0
HKD1_k127_2403792_2 LVIVD repeat - - - 0.0000000000000000000000000000000002527 149.0
HKD1_k127_2403792_3 Domain of unkown function (DUF1775) - - - 0.0000000000000000006423 98.0
HKD1_k127_2403792_4 Rhodanese Homology Domain - - - 0.0002281 47.0
HKD1_k127_2421811_0 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 443.0
HKD1_k127_2421811_1 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 415.0
HKD1_k127_2421811_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 348.0
HKD1_k127_2421811_3 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002345 301.0
HKD1_k127_2421811_4 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000002542 207.0
HKD1_k127_2429047_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 7.348e-290 928.0
HKD1_k127_2429047_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 6.455e-277 873.0
HKD1_k127_2429047_10 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 539.0
HKD1_k127_2429047_100 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0005322 47.0
HKD1_k127_2429047_11 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 511.0
HKD1_k127_2429047_12 ABC transporter permease K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 501.0
HKD1_k127_2429047_13 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009979 473.0
HKD1_k127_2429047_14 Dehydrogenase K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 455.0
HKD1_k127_2429047_15 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 461.0
HKD1_k127_2429047_16 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 444.0
HKD1_k127_2429047_17 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 457.0
HKD1_k127_2429047_18 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 426.0
HKD1_k127_2429047_19 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 454.0
HKD1_k127_2429047_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.083e-260 813.0
HKD1_k127_2429047_20 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 411.0
HKD1_k127_2429047_21 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 413.0
HKD1_k127_2429047_22 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 413.0
HKD1_k127_2429047_23 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 409.0
HKD1_k127_2429047_24 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 392.0
HKD1_k127_2429047_25 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 394.0
HKD1_k127_2429047_26 PFAM ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 390.0
HKD1_k127_2429047_27 Sigma-54 interaction domain K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 395.0
HKD1_k127_2429047_28 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 374.0
HKD1_k127_2429047_29 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 398.0
HKD1_k127_2429047_3 AMP-binding enzyme K01897 - 6.2.1.3 1.286e-248 798.0
HKD1_k127_2429047_30 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 364.0
HKD1_k127_2429047_31 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 379.0
HKD1_k127_2429047_32 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 369.0
HKD1_k127_2429047_33 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 370.0
HKD1_k127_2429047_34 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 348.0
HKD1_k127_2429047_35 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 347.0
HKD1_k127_2429047_36 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 346.0
HKD1_k127_2429047_37 Belongs to the TtcA family K21947 - 2.8.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 340.0
HKD1_k127_2429047_38 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 327.0
HKD1_k127_2429047_39 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 319.0
HKD1_k127_2429047_4 Radical SAM - - - 5.999e-221 696.0
HKD1_k127_2429047_40 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 311.0
HKD1_k127_2429047_41 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 304.0
HKD1_k127_2429047_42 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 322.0
HKD1_k127_2429047_43 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 295.0
HKD1_k127_2429047_44 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 289.0
HKD1_k127_2429047_45 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003406 282.0
HKD1_k127_2429047_46 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006957 268.0
HKD1_k127_2429047_47 Belongs to the LDH2 MDH2 oxidoreductase family K00073 - 1.1.1.350 0.00000000000000000000000000000000000000000000000000000000000000000000000000001124 291.0
HKD1_k127_2429047_48 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003018 271.0
HKD1_k127_2429047_49 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003281 260.0
HKD1_k127_2429047_5 benzoyl-CoA oxygenase - - - 2.582e-219 686.0
HKD1_k127_2429047_50 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000008122 272.0
HKD1_k127_2429047_51 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000107 279.0
HKD1_k127_2429047_52 COG0559 Branched-chain amino acid ABC-type transport system, permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001001 261.0
HKD1_k127_2429047_53 Polysaccharide export protein K01991,K20988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008533 248.0
HKD1_k127_2429047_54 serine-type endopeptidase activity K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000000001021 246.0
HKD1_k127_2429047_55 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000406 262.0
HKD1_k127_2429047_56 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000002015 243.0
HKD1_k127_2429047_57 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000006823 244.0
HKD1_k127_2429047_58 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001819 243.0
HKD1_k127_2429047_59 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000001474 232.0
HKD1_k127_2429047_6 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 7.212e-214 685.0
HKD1_k127_2429047_60 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000002258 214.0
HKD1_k127_2429047_61 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000004857 209.0
HKD1_k127_2429047_62 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000179 201.0
HKD1_k127_2429047_63 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000001108 198.0
HKD1_k127_2429047_64 Dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000008617 199.0
HKD1_k127_2429047_65 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000002747 192.0
HKD1_k127_2429047_66 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000004798 183.0
HKD1_k127_2429047_67 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000005781 173.0
HKD1_k127_2429047_68 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000001455 174.0
HKD1_k127_2429047_69 MaoC like domain - - - 0.0000000000000000000000000000000000000000005335 161.0
HKD1_k127_2429047_7 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.805e-203 663.0
HKD1_k127_2429047_70 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000006317 166.0
HKD1_k127_2429047_71 Scavenger mRNA decapping enzyme C-term binding - - - 0.000000000000000000000000000000000000000008411 157.0
HKD1_k127_2429047_72 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000000000000000004877 156.0
HKD1_k127_2429047_73 Enoyl-CoA hydratase K16425 GO:0003674,GO:0003824,GO:0004300,GO:0016829,GO:0016835,GO:0016836 - 0.0000000000000000000000000000000000000007817 158.0
HKD1_k127_2429047_74 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000005955 152.0
HKD1_k127_2429047_75 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000007845 144.0
HKD1_k127_2429047_76 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000005673 140.0
HKD1_k127_2429047_77 COG2346, Truncated hemoglobins K06886 - - 0.0000000000000000000000000000001649 139.0
HKD1_k127_2429047_79 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000001558 132.0
HKD1_k127_2429047_8 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 623.0
HKD1_k127_2429047_80 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000344 128.0
HKD1_k127_2429047_81 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000003326 121.0
HKD1_k127_2429047_83 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000003709 118.0
HKD1_k127_2429047_84 phosphatase activity K07025 - - 0.00000000000000000000002414 110.0
HKD1_k127_2429047_85 SnoaL-like domain - - - 0.00000000000000000000009421 111.0
HKD1_k127_2429047_86 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000001778 104.0
HKD1_k127_2429047_87 Putative beta-barrel porin 2 K20920 - - 0.000000000000000000001203 109.0
HKD1_k127_2429047_88 Cupin domain - - - 0.00000000000000000004644 96.0
HKD1_k127_2429047_89 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000006718 98.0
HKD1_k127_2429047_9 Carboxyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 621.0
HKD1_k127_2429047_90 MORN repeat variant - - - 0.000000000000001611 87.0
HKD1_k127_2429047_91 ATPase, P-type (transporting), HAD superfamily, subfamily IC K12955 - - 0.000000000000007398 84.0
HKD1_k127_2429047_92 phosphorelay signal transduction system - - - 0.00000000000002242 87.0
HKD1_k127_2429047_93 thiamine diphosphate biosynthetic process K03154 - - 0.00000000001709 74.0
HKD1_k127_2429047_94 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.0000000006779 64.0
HKD1_k127_2429047_96 CDP-alcohol phosphatidyltransferase - - - 0.000000002373 70.0
HKD1_k127_2429047_97 - - - - 0.00004824 51.0
HKD1_k127_2429047_98 Beta-ketoacyl synthase, N-terminal domain K09458 - 2.3.1.179 0.00008056 55.0
HKD1_k127_2429047_99 - - - - 0.0002418 49.0
HKD1_k127_244530_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 437.0
HKD1_k127_244530_1 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 346.0
HKD1_k127_244530_10 PFAM Glycosyl transferase family 2 - - - 0.0000000001683 65.0
HKD1_k127_244530_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000005275 66.0
HKD1_k127_244530_12 polysaccharide K01991,K20987 - - 0.0000005083 63.0
HKD1_k127_244530_2 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 336.0
HKD1_k127_244530_3 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 325.0
HKD1_k127_244530_4 Polysaccharide export protein K01991,K20988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002433 278.0
HKD1_k127_244530_5 Polysaccharide export protein K01991,K20988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003881 273.0
HKD1_k127_244530_6 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000008156 247.0
HKD1_k127_244530_7 CobQ CobB MinD ParA nucleotide binding domain K16554,K16692 - - 0.0000000000000000000000000000000000000000000000000000000001794 212.0
HKD1_k127_244530_8 O-Antigen ligase K18814 - - 0.0000000000000000000000000000000001112 154.0
HKD1_k127_244530_9 protein methyltransferase activity - - - 0.000000000000000000000000005692 122.0
HKD1_k127_2563798_0 elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 602.0
HKD1_k127_2563798_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 602.0
HKD1_k127_2563798_10 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000002426 248.0
HKD1_k127_2563798_11 Glycosyltransferase like family 2 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000008948 211.0
HKD1_k127_2563798_12 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000001274 195.0
HKD1_k127_2563798_13 Protein of unknown function (DUF2723) - - - 0.00000000000000000000000000000000000000007589 173.0
HKD1_k127_2563798_14 Protein of unknown function (DUF3105) - - - 0.00000000000000000000000000000000001515 156.0
HKD1_k127_2563798_15 N-terminal domain of galactosyltransferase - - - 0.00000000000000000000000000002816 130.0
HKD1_k127_2563798_16 ATP hydrolysis coupled proton transport - - - 0.00000000000000000000000000009244 133.0
HKD1_k127_2563798_17 Bacterial sugar transferase - - - 0.00000000000000000000002654 100.0
HKD1_k127_2563798_18 PFAM phosphatidate cytidylyltransferase - - - 0.0000000000000378 81.0
HKD1_k127_2563798_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002452 69.0
HKD1_k127_2563798_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 443.0
HKD1_k127_2563798_20 methyltransferase - - - 0.000000001085 70.0
HKD1_k127_2563798_3 Extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009197 331.0
HKD1_k127_2563798_4 Wzt C-terminal domain K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 335.0
HKD1_k127_2563798_5 ABC-2 type transporter K01992,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 308.0
HKD1_k127_2563798_6 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 325.0
HKD1_k127_2563798_7 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 306.0
HKD1_k127_2563798_8 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02031,K02032,K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006375 297.0
HKD1_k127_2563798_9 3-demethylubiquinone-9 3-O-methyltransferase activity K06219 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005441 279.0
HKD1_k127_258477_0 Proline dehydrogenase K13821 - 1.2.1.88,1.5.5.2 0.0 1134.0
HKD1_k127_258477_1 Major facilitator superfamily K03449 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001214 280.0
HKD1_k127_258477_10 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0008935 53.0
HKD1_k127_258477_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001006 254.0
HKD1_k127_258477_3 Protein of unknown function (DUF2652) - - - 0.000000000000000000000000000000000009691 150.0
HKD1_k127_258477_4 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000001315 150.0
HKD1_k127_258477_5 Hep Hag repeat protein - - - 0.000000000000000000000000004251 118.0
HKD1_k127_258477_7 ACT domain protein - - - 0.000000000000003614 83.0
HKD1_k127_258477_8 ligase activity - - - 0.00004945 50.0
HKD1_k127_261840_0 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 323.0
HKD1_k127_261840_1 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 288.0
HKD1_k127_261840_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001925 249.0
HKD1_k127_261840_3 Parallel beta-helix repeats - - - 0.0000000000000000000000000005073 124.0
HKD1_k127_261840_4 - - - - 0.00000000000000004007 83.0
HKD1_k127_261840_5 - - - - 0.0000003216 61.0
HKD1_k127_261840_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00009115 53.0
HKD1_k127_261840_7 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.0001707 53.0
HKD1_k127_2653522_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 562.0
HKD1_k127_2653522_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 464.0
HKD1_k127_2653522_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 421.0
HKD1_k127_2653522_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18983 - 5.5.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 353.0
HKD1_k127_2653522_4 PFAM alanine racemase domain protein K20757 - 4.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 293.0
HKD1_k127_2653522_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000001507 224.0
HKD1_k127_2653522_6 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000217 147.0
HKD1_k127_2653522_7 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000005713 68.0
HKD1_k127_2728762_0 DEAD/H associated K03724 - - 0.0 1341.0
HKD1_k127_2728762_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.409e-287 912.0
HKD1_k127_2728762_10 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 394.0
HKD1_k127_2728762_11 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 384.0
HKD1_k127_2728762_12 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 352.0
HKD1_k127_2728762_13 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 358.0
HKD1_k127_2728762_14 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 324.0
HKD1_k127_2728762_15 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 317.0
HKD1_k127_2728762_16 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 319.0
HKD1_k127_2728762_17 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 304.0
HKD1_k127_2728762_18 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 301.0
HKD1_k127_2728762_19 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001611 284.0
HKD1_k127_2728762_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 3.548e-258 807.0
HKD1_k127_2728762_20 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000000007167 256.0
HKD1_k127_2728762_21 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007996 249.0
HKD1_k127_2728762_22 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000001496 216.0
HKD1_k127_2728762_23 Uracil phosphoribosyltransferase K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000001082 216.0
HKD1_k127_2728762_24 nucleoside 2-deoxyribosyltransferase K08728 - 2.4.2.6 0.000000000000000000000000000000000000000000000000001019 190.0
HKD1_k127_2728762_25 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000000001546 155.0
HKD1_k127_2728762_3 COGs COG3533 conserved K09955 - - 9.297e-213 677.0
HKD1_k127_2728762_4 transport systems, ATPase components K02056 - 3.6.3.17 2.388e-194 637.0
HKD1_k127_2728762_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 640.0
HKD1_k127_2728762_6 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 507.0
HKD1_k127_2728762_7 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 460.0
HKD1_k127_2728762_8 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 424.0
HKD1_k127_2728762_9 Pyrimidine nucleoside phosphorylase C-terminal domain K00758 - 2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 424.0
HKD1_k127_281465_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 3.121e-284 905.0
HKD1_k127_281465_1 Phosphate acyltransferases K01897 - 6.2.1.3 5.267e-270 859.0
HKD1_k127_281465_10 dihydrodipicolinate reductase - - - 0.00000000000000000000000000000000000000000000000000000009305 219.0
HKD1_k127_281465_11 BON domain K04065 - - 0.000000000000000000000000000000000000000000000000000002728 211.0
HKD1_k127_281465_12 Trypsin - - - 0.00000000000000000000000000000000000000000000002456 181.0
HKD1_k127_281465_13 Forkhead associated domain - - - 0.00000000000000000000000000000000000001616 164.0
HKD1_k127_281465_14 CBS domain K04767 - - 0.000000000000000000000000005399 118.0
HKD1_k127_281465_15 ligase activity - - - 0.000000000000000000000002671 107.0
HKD1_k127_281465_16 Protein of unknown function (DUF3175) - - - 0.0000000000000000017 93.0
HKD1_k127_281465_17 - - - - 0.000000000000003574 80.0
HKD1_k127_281465_18 PFAM THUMP domain protein K06963 - - 0.000000005495 66.0
HKD1_k127_281465_19 Universal stress protein family - - - 0.00000005193 63.0
HKD1_k127_281465_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.859e-198 636.0
HKD1_k127_281465_20 Uncharacterized conserved protein (DUF2267) - - - 0.00002618 56.0
HKD1_k127_281465_3 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008742 496.0
HKD1_k127_281465_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 457.0
HKD1_k127_281465_5 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 369.0
HKD1_k127_281465_6 Phosphomethylpyrimidine kinase K16370 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 341.0
HKD1_k127_281465_7 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004131 286.0
HKD1_k127_281465_8 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001985 289.0
HKD1_k127_281465_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000003573 245.0
HKD1_k127_2877303_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0 1501.0
HKD1_k127_2877303_1 Heat shock 70 kDa protein K04043 - - 5.556e-310 960.0
HKD1_k127_2877303_10 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 410.0
HKD1_k127_2877303_11 Amidohydrolase family K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 377.0
HKD1_k127_2877303_12 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 380.0
HKD1_k127_2877303_13 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 349.0
HKD1_k127_2877303_14 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 309.0
HKD1_k127_2877303_15 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002865 299.0
HKD1_k127_2877303_16 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004592 282.0
HKD1_k127_2877303_17 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001859 276.0
HKD1_k127_2877303_18 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003951 285.0
HKD1_k127_2877303_19 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007439 267.0
HKD1_k127_2877303_2 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 2.209e-271 864.0
HKD1_k127_2877303_20 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000418 251.0
HKD1_k127_2877303_21 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000001649 244.0
HKD1_k127_2877303_22 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000001712 261.0
HKD1_k127_2877303_23 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001319 250.0
HKD1_k127_2877303_24 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000005791 241.0
HKD1_k127_2877303_25 Essential for recycling GMP and indirectly, cGMP K00942,K01591 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000001346 222.0
HKD1_k127_2877303_26 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000002621 226.0
HKD1_k127_2877303_27 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000831 235.0
HKD1_k127_2877303_28 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000002056 206.0
HKD1_k127_2877303_29 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000001667 201.0
HKD1_k127_2877303_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.382e-263 845.0
HKD1_k127_2877303_30 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000008565 207.0
HKD1_k127_2877303_31 Orotidine 5'-phosphate decarboxylase / HUMPS family K13421 - 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000000000000000000006391 193.0
HKD1_k127_2877303_32 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000001033 163.0
HKD1_k127_2877303_33 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000004752 157.0
HKD1_k127_2877303_34 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000006735 156.0
HKD1_k127_2877303_35 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000919 133.0
HKD1_k127_2877303_36 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000001541 138.0
HKD1_k127_2877303_37 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000002096 128.0
HKD1_k127_2877303_38 Ribosomal protein S16 K02959 - - 0.00000000000000000000000003116 110.0
HKD1_k127_2877303_39 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000001363 105.0
HKD1_k127_2877303_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 531.0
HKD1_k127_2877303_40 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000008934 104.0
HKD1_k127_2877303_41 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000001439 89.0
HKD1_k127_2877303_42 COG0584 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000003696 79.0
HKD1_k127_2877303_43 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000001065 71.0
HKD1_k127_2877303_44 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000266 55.0
HKD1_k127_2877303_45 - - - - 0.00004651 54.0
HKD1_k127_2877303_5 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 531.0
HKD1_k127_2877303_6 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 502.0
HKD1_k127_2877303_7 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 495.0
HKD1_k127_2877303_8 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 467.0
HKD1_k127_2877303_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 439.0
HKD1_k127_3026165_0 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 0.0 1070.0
HKD1_k127_3026165_1 COG0346 Lactoylglutathione lyase and related lyases K07032 - - 0.00000000000000000000000000000000000000000000000000008247 201.0
HKD1_k127_3026165_2 - - - - 0.0000000000000000000002363 101.0
HKD1_k127_3044598_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 531.0
HKD1_k127_3044598_1 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 433.0
HKD1_k127_3044598_2 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 339.0
HKD1_k127_3044598_3 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000003842 243.0
HKD1_k127_3044598_4 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000003004 187.0
HKD1_k127_3044598_5 Nodulation protein S (NodS) - - - 0.00000000000000000000000000005348 124.0
HKD1_k127_3044598_6 Protein of unknown function (DUF1810) - - - 0.00000000000004363 77.0
HKD1_k127_3158147_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.515e-260 812.0
HKD1_k127_3158147_1 PFAM Phenylalanine and histidine ammonia-lyase K01745,K10775 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009698,GO:0009699,GO:0009800,GO:0009803,GO:0009987,GO:0016043,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019748,GO:0019752,GO:0022607,GO:0032787,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044550,GO:0045548,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 4.3.1.24,4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 498.0
HKD1_k127_3158147_2 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001673 273.0
HKD1_k127_3158147_3 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006812 272.0
HKD1_k127_3158147_4 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000000000000002785 176.0
HKD1_k127_3158147_5 Lipocalin-like domain - - - 0.0000000000000000000000000000000008505 135.0
HKD1_k127_3158147_7 Glycosyltransferase Family 4 K14335 - - 0.000001762 60.0
HKD1_k127_3227757_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 3.139e-264 832.0
HKD1_k127_3227757_1 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 1.334e-260 812.0
HKD1_k127_3227757_10 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 350.0
HKD1_k127_3227757_11 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 342.0
HKD1_k127_3227757_12 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 330.0
HKD1_k127_3227757_13 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 331.0
HKD1_k127_3227757_14 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 312.0
HKD1_k127_3227757_15 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 318.0
HKD1_k127_3227757_16 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007527 288.0
HKD1_k127_3227757_17 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000001567 192.0
HKD1_k127_3227757_18 PFAM Stage II sporulation K06381 - - 0.0000000000000000000000000000000000000000000000000000225 209.0
HKD1_k127_3227757_19 - - - - 0.000000000000000000000000000000000000000000000007064 183.0
HKD1_k127_3227757_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.124e-202 655.0
HKD1_k127_3227757_20 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000002201 192.0
HKD1_k127_3227757_21 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000001358 176.0
HKD1_k127_3227757_22 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000007013 166.0
HKD1_k127_3227757_23 COG0073 EMAP domain K06878 GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000008724 150.0
HKD1_k127_3227757_24 - - - - 0.0000000000000000000000000000000002041 140.0
HKD1_k127_3227757_25 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000005089 148.0
HKD1_k127_3227757_26 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000001253 131.0
HKD1_k127_3227757_27 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000001948 118.0
HKD1_k127_3227757_28 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000002178 114.0
HKD1_k127_3227757_29 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000001289 96.0
HKD1_k127_3227757_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 488.0
HKD1_k127_3227757_30 Preprotein translocase subunit K03210 - - 0.000000000000000009392 97.0
HKD1_k127_3227757_31 Protein of unknown function (DUF2905) - - - 0.00000000001541 76.0
HKD1_k127_3227757_4 D-arabinono-1,4-lactone oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 493.0
HKD1_k127_3227757_5 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 457.0
HKD1_k127_3227757_6 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 441.0
HKD1_k127_3227757_7 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 431.0
HKD1_k127_3227757_8 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 434.0
HKD1_k127_3227757_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 407.0
HKD1_k127_3230400_0 Sulfatase K01130 - 3.1.6.1 0.0 1364.0
HKD1_k127_3230400_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1127.0
HKD1_k127_3230400_10 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 400.0
HKD1_k127_3230400_11 Associated with various cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 392.0
HKD1_k127_3230400_12 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 401.0
HKD1_k127_3230400_13 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 376.0
HKD1_k127_3230400_14 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 371.0
HKD1_k127_3230400_15 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 346.0
HKD1_k127_3230400_16 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 357.0
HKD1_k127_3230400_17 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 344.0
HKD1_k127_3230400_18 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 340.0
HKD1_k127_3230400_19 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 342.0
HKD1_k127_3230400_2 xanthine dehydrogenase activity K03520 - 1.2.5.3 0.0 1094.0
HKD1_k127_3230400_20 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 345.0
HKD1_k127_3230400_21 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 323.0
HKD1_k127_3230400_22 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 336.0
HKD1_k127_3230400_23 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 342.0
HKD1_k127_3230400_24 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 309.0
HKD1_k127_3230400_25 tRNA processing K06864,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 293.0
HKD1_k127_3230400_26 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003425 280.0
HKD1_k127_3230400_27 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002998 283.0
HKD1_k127_3230400_28 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002902 273.0
HKD1_k127_3230400_29 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000003203 269.0
HKD1_k127_3230400_3 Arylsulfatase K01130 - 3.1.6.1 6.077e-268 838.0
HKD1_k127_3230400_30 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008508 276.0
HKD1_k127_3230400_31 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004951 256.0
HKD1_k127_3230400_32 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000002855 244.0
HKD1_k127_3230400_33 (Rhomboid) family - - - 0.0000000000000000000000000000000000000000000000000000000000000001068 245.0
HKD1_k127_3230400_34 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000002055 232.0
HKD1_k127_3230400_35 Peptidase family M16 - - - 0.00000000000000000000000000000000000000000000000000000000000006506 240.0
HKD1_k127_3230400_36 Ceramidase - - - 0.000000000000000000000000000000000000000000000000000000000003579 227.0
HKD1_k127_3230400_37 'Molybdopterin - - - 0.0000000000000000000000000000000000000000000000000000000247 222.0
HKD1_k127_3230400_38 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000001307 169.0
HKD1_k127_3230400_39 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.00000000000000000000000000000000000002918 147.0
HKD1_k127_3230400_4 Belongs to the TPP enzyme family K01576 - 4.1.1.7 4.438e-238 750.0
HKD1_k127_3230400_40 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000002436 163.0
HKD1_k127_3230400_41 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000001841 160.0
HKD1_k127_3230400_42 Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000009138 127.0
HKD1_k127_3230400_43 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000009928 119.0
HKD1_k127_3230400_44 NifU-like N terminal domain K04488 - - 0.0000000000000000000001036 102.0
HKD1_k127_3230400_45 CAAX protease self-immunity K07052 - - 0.00000000002331 74.0
HKD1_k127_3230400_46 Nitroreductase family - - - 0.00000002091 59.0
HKD1_k127_3230400_5 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 585.0
HKD1_k127_3230400_6 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 494.0
HKD1_k127_3230400_7 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 464.0
HKD1_k127_3230400_8 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 430.0
HKD1_k127_3230400_9 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 415.0
HKD1_k127_3237549_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 554.0
HKD1_k127_3237549_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 533.0
HKD1_k127_3237549_10 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 297.0
HKD1_k127_3237549_11 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 290.0
HKD1_k127_3237549_12 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001068 280.0
HKD1_k127_3237549_13 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005381 304.0
HKD1_k127_3237549_14 phosphorelay sensor kinase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009981 294.0
HKD1_k127_3237549_15 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000001819 263.0
HKD1_k127_3237549_16 NAD(P)H-dependent FMN reductase K19784 - - 0.00000000000000000000000000000000000000000000000000000000000000002383 233.0
HKD1_k127_3237549_17 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000002462 218.0
HKD1_k127_3237549_18 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000004152 211.0
HKD1_k127_3237549_19 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000002266 204.0
HKD1_k127_3237549_2 MreB/Mbl protein K03569 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 497.0
HKD1_k127_3237549_20 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000001065 209.0
HKD1_k127_3237549_21 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000002951 200.0
HKD1_k127_3237549_22 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000003385 194.0
HKD1_k127_3237549_23 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000005302 205.0
HKD1_k127_3237549_24 Domain of unknown function (DUF4392) - - - 0.0000000000000000000000000000000000000000000000007341 190.0
HKD1_k127_3237549_25 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000001479 175.0
HKD1_k127_3237549_26 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000001452 164.0
HKD1_k127_3237549_27 PFAM CBS domain containing protein K04767 - - 0.0000000000000000000000000000000004389 139.0
HKD1_k127_3237549_28 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000008647 145.0
HKD1_k127_3237549_29 PFAM HNH endonuclease K07451 - - 0.0000000000000000000000000000005029 135.0
HKD1_k127_3237549_3 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 503.0
HKD1_k127_3237549_30 RNA recognition motif - - - 0.0000000000000000008066 91.0
HKD1_k127_3237549_31 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000314 90.0
HKD1_k127_3237549_32 rod shape-determining protein MreD K03571 - - 0.0000000000000135 79.0
HKD1_k127_3237549_33 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000002677 85.0
HKD1_k127_3237549_34 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000006782 65.0
HKD1_k127_3237549_35 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000001657 69.0
HKD1_k127_3237549_36 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0001025 49.0
HKD1_k127_3237549_37 ATP-dependent helicase K11647 GO:0000003,GO:0000122,GO:0000228,GO:0000785,GO:0000790,GO:0000791,GO:0000792,GO:0000902,GO:0000904,GO:0000976,GO:0000977,GO:0000978,GO:0000987,GO:0001012,GO:0001013,GO:0001046,GO:0001047,GO:0001067,GO:0001163,GO:0001164,GO:0001188,GO:0001221,GO:0001223,GO:0001558,GO:0001568,GO:0001570,GO:0001654,GO:0001701,GO:0001709,GO:0001824,GO:0001832,GO:0001835,GO:0001889,GO:0001944,GO:0002009,GO:0002039,GO:0002064,GO:0002088,GO:0002165,GO:0002262,GO:0002376,GO:0002520,GO:0002682,GO:0003002,GO:0003006,GO:0003007,GO:0003151,GO:0003205,GO:0003206,GO:0003231,GO:0003279,GO:0003281,GO:0003407,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003712,GO:0003713,GO:0003714,GO:0003824,GO:0004386,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005719,GO:0005726,GO:0005730,GO:0005856,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006337,GO:0006338,GO:0006342,GO:0006346,GO:0006351,GO:0006352,GO:0006355,GO:0006356,GO:0006357,GO:0006360,GO:0006361,GO:0006464,GO:0006473,GO:0006475,GO:0006725,GO:0006807,GO:0006928,GO:0006935,GO:0006996,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007292,GO:0007346,GO:0007389,GO:0007399,GO:0007403,GO:0007406,GO:0007409,GO:0007417,GO:0007420,GO:0007423,GO:0007444,GO:0007472,GO:0007474,GO:0007476,GO:0007478,GO:0007480,GO:0007507,GO:0007552,GO:0007560,GO:0008094,GO:0008134,GO:0008150,GO:0008152,GO:0008283,GO:0008284,GO:0008285,GO:0008544,GO:0008586,GO:0008587,GO:0009058,GO:0009059,GO:0009605,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009913,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010001,GO:0010033,GO:0010424,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010721,GO:0010941,GO:0010948,GO:0016043,GO:0016070,GO:0016358,GO:0016458,GO:0016462,GO:0016514,GO:0016569,GO:0016570,GO:0016573,GO:0016586,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019221,GO:0019222,GO:0019438,GO:0019538,GO:0019827,GO:0019899,GO:0019953,GO:0021781,GO:0022008,GO:0022411,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030030,GO:0030097,GO:0030099,GO:0030111,GO:0030154,GO:0030177,GO:0030182,GO:0030198,GO:0030216,GO:0030218,GO:0030308,GO:0030326,GO:0030334,GO:0030855,GO:0030900,GO:0030902,GO:0030957,GO:0031175,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031347,GO:0031497,GO:0031498,GO:0031974,GO:0031981,GO:0032259,GO:0032501,GO:0032502,GO:0032504,GO:0032774,GO:0032776,GO:0032879,GO:0032984,GO:0032986,GO:0032989,GO:0032990,GO:0032991,GO:0033143,GO:0033144,GO:0034097,GO:0034101,GO:0034622,GO:0034641,GO:0034645,GO:0034654,GO:0034728,GO:0035060,GO:0035107,GO:0035108,GO:0035113,GO:0035114,GO:0035116,GO:0035120,GO:0035137,GO:0035172,GO:0035188,GO:0035218,GO:0035220,GO:0035239,GO:0035257,GO:0035258,GO:0035295,GO:0035821,GO:0035886,GO:0035887,GO:0035904,GO:0036211,GO:0036335,GO:0038111,GO:0040007,GO:0040008,GO:0040011,GO:0040012,GO:0040029,GO:0042058,GO:0042063,GO:0042127,GO:0042221,GO:0042330,GO:0042393,GO:0042592,GO:0042623,GO:0042692,GO:0042981,GO:0043009,GO:0043010,GO:0043044,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043388,GO:0043412,GO:0043414,GO:0043543,GO:0043565,GO:0043588,GO:0043696,GO:0043697,GO:0043900,GO:0043902,GO:0043903,GO:0043921,GO:0043923,GO:0043933,GO:0043966,GO:0043974,GO:0044085,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0044703,GO:0044728,GO:0044877,GO:0045088,GO:0045111,GO:0045165,GO:0045595,GO:0045596,GO:0045597,GO:0045742,GO:0045786,GO:0045814,GO:0045892,GO:0045893,GO:0045926,GO:0045930,GO:0045934,GO:0045935,GO:0045943,GO:0045944,GO:0046483,GO:0046782,GO:0047485,GO:0048232,GO:0048468,GO:0048477,GO:0048513,GO:0048514,GO:0048515,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0048534,GO:0048562,GO:0048563,GO:0048568,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048598,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048707,GO:0048729,GO:0048730,GO:0048731,GO:0048732,GO:0048736,GO:0048737,GO:0048812,GO:0048813,GO:0048844,GO:0048856,GO:0048858,GO:0048869,GO:0048872,GO:0050434,GO:0050681,GO:0050767,GO:0050768,GO:0050776,GO:0050789,GO:0050792,GO:0050793,GO:0050794,GO:0050896,GO:0051090,GO:0051091,GO:0051093,GO:0051094,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0051145,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051241,GO:0051252,GO:0051253,GO:0051254,GO:0051270,GO:0051276,GO:0051427,GO:0051702,GO:0051704,GO:0051716,GO:0051726,GO:0051817,GO:0051851,GO:0051960,GO:0051961,GO:0052312,GO:0052472,GO:0060037,GO:0060041,GO:0060173,GO:0060216,GO:0060255,GO:0060284,GO:0060318,GO:0060322,GO:0060343,GO:0060347,GO:0060429,GO:0060548,GO:0060562,GO:0060765,GO:0060766,GO:0060840,GO:0060976,GO:0061008,GO:0061061,GO:0061383,GO:0061384,GO:0061564,GO:0061626,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070182,GO:0070306,GO:0070307,GO:0070577,GO:0070603,GO:0070887,GO:0070897,GO:0070983,GO:0071103,GO:0071310,GO:0071345,GO:0071564,GO:0071565,GO:0071684,GO:0071704,GO:0071824,GO:0071840,GO:0072091,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090304,GO:0097159,GO:0097458,GO:0097485,GO:0097659,GO:0098727,GO:0098760,GO:0098761,GO:0120036,GO:0120039,GO:0140030,GO:0140033,GO:0140110,GO:1901184,GO:1901186,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901836,GO:1901838,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902494,GO:1902659,GO:1902661,GO:1902679,GO:1902680,GO:1902692,GO:1902806,GO:1902807,GO:1902893,GO:1902895,GO:1903506,GO:1903507,GO:1903508,GO:1904837,GO:1904949,GO:1990837,GO:2000026,GO:2000045,GO:2000112,GO:2000113,GO:2000134,GO:2000145,GO:2000177,GO:2000178,GO:2000647,GO:2000648,GO:2001141 - 0.0002229 48.0
HKD1_k127_3237549_4 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 447.0
HKD1_k127_3237549_5 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 444.0
HKD1_k127_3237549_6 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 423.0
HKD1_k127_3237549_7 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 426.0
HKD1_k127_3237549_8 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 421.0
HKD1_k127_3237549_9 Hydrogenase expression formation protein (HypE) K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 352.0
HKD1_k127_3276201_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 562.0
HKD1_k127_3276201_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 531.0
HKD1_k127_3276201_10 Bacterial transferase hexapeptide (six repeats) K00640 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 293.0
HKD1_k127_3276201_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 295.0
HKD1_k127_3276201_12 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004728 299.0
HKD1_k127_3276201_13 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002348 291.0
HKD1_k127_3276201_14 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001045 281.0
HKD1_k127_3276201_15 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000003251 274.0
HKD1_k127_3276201_16 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003723 266.0
HKD1_k127_3276201_17 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004214 265.0
HKD1_k127_3276201_18 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001201 291.0
HKD1_k127_3276201_19 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001551 265.0
HKD1_k127_3276201_2 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 540.0
HKD1_k127_3276201_20 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003524 267.0
HKD1_k127_3276201_21 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00847,K00852 GO:0003674,GO:0003824,GO:0004747,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019303,GO:0019321,GO:0019323,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.15,2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000583 259.0
HKD1_k127_3276201_22 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000006469 213.0
HKD1_k127_3276201_23 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000007943 126.0
HKD1_k127_3276201_24 CoA binding domain - - - 0.0000000000000000000000000000001745 132.0
HKD1_k127_3276201_25 Iron-sulphur cluster biosynthesis K13628 - - 0.00000000000000000000000000001201 125.0
HKD1_k127_3276201_26 NifU-like N terminal domain - - - 0.0000000000000000000000000004989 130.0
HKD1_k127_3276201_27 Transcriptional regulator - - - 0.000000000000000000000000006784 128.0
HKD1_k127_3276201_28 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.000000000000000000000001819 106.0
HKD1_k127_3276201_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 446.0
HKD1_k127_3276201_30 FeS assembly protein IscX - - - 0.0000000000000000187 90.0
HKD1_k127_3276201_31 TPR repeat - - - 0.00000000000000006514 94.0
HKD1_k127_3276201_32 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.00000000000001436 82.0
HKD1_k127_3276201_33 Biotin-requiring enzyme - - - 0.00000000000136 76.0
HKD1_k127_3276201_34 Rdx family K07401 - - 0.00000005062 56.0
HKD1_k127_3276201_4 ATPase associated with K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 400.0
HKD1_k127_3276201_5 Sigma-70 factor, region 1.1 K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 390.0
HKD1_k127_3276201_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 362.0
HKD1_k127_3276201_7 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 355.0
HKD1_k127_3276201_8 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 323.0
HKD1_k127_3276201_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 303.0
HKD1_k127_3325246_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1641.0
HKD1_k127_3325246_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1386.0
HKD1_k127_3325246_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 314.0
HKD1_k127_3325246_3 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000007756 234.0
HKD1_k127_3325246_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000004099 218.0
HKD1_k127_3325246_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000006133 154.0
HKD1_k127_3325246_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000005856 136.0
HKD1_k127_3325246_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000006016 86.0
HKD1_k127_3325246_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001413 79.0
HKD1_k127_3325246_9 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000002158 58.0
HKD1_k127_3432284_0 Amino acid permease - - - 4.796e-195 627.0
HKD1_k127_3432284_1 Replicative DNA helicase K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 465.0
HKD1_k127_3432284_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 378.0
HKD1_k127_3432284_3 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000002239 262.0
HKD1_k127_3432284_4 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000004017 169.0
HKD1_k127_3432284_5 endonuclease III K01247 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 0.00000000000000000000000000000000000000004635 164.0
HKD1_k127_3432284_6 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000005128 136.0
HKD1_k127_3432284_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000004454 109.0
HKD1_k127_3432284_8 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000444 82.0
HKD1_k127_3432284_9 Predicted membrane protein (DUF2232) K16785,K16786,K16787 - - 0.000000000000002438 87.0
HKD1_k127_3513800_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 507.0
HKD1_k127_3513800_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 375.0
HKD1_k127_3513800_10 - - - - 0.00000000000000000000000000000000005123 141.0
HKD1_k127_3513800_11 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000004617 130.0
HKD1_k127_3513800_12 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000005749 102.0
HKD1_k127_3513800_2 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 359.0
HKD1_k127_3513800_3 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16165 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0008948,GO:0016787,GO:0016822,GO:0016823,GO:0016829,GO:0016830,GO:0016831,GO:0018773,GO:0031974,GO:0031981,GO:0034545,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0070013 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 336.0
HKD1_k127_3513800_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 326.0
HKD1_k127_3513800_5 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 319.0
HKD1_k127_3513800_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 295.0
HKD1_k127_3513800_7 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001407 255.0
HKD1_k127_3513800_8 - - - - 0.000000000000000000000000000000000000000000000000653 184.0
HKD1_k127_3513800_9 belongs to the thioredoxin family K03671,K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.00000000000000000000000000000000000005714 154.0
HKD1_k127_351761_0 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.969e-210 679.0
HKD1_k127_351761_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.604e-203 649.0
HKD1_k127_351761_10 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 294.0
HKD1_k127_351761_11 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000691 231.0
HKD1_k127_351761_12 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00000000000000000000000000000000000000000000002499 186.0
HKD1_k127_351761_13 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000004214 149.0
HKD1_k127_351761_14 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000001421 101.0
HKD1_k127_351761_15 TonB C terminal K03832 - - 0.000000000006337 75.0
HKD1_k127_351761_16 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000002605 66.0
HKD1_k127_351761_17 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000007246 66.0
HKD1_k127_351761_18 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000004778 68.0
HKD1_k127_351761_19 Putative addiction module component - - - 0.00000000188 63.0
HKD1_k127_351761_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 561.0
HKD1_k127_351761_20 Glycosyl transferase family group 2 - - - 0.000000003435 70.0
HKD1_k127_351761_21 - - - - 0.00000007044 56.0
HKD1_k127_351761_22 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000000092 65.0
HKD1_k127_351761_23 Prokaryotic N-terminal methylation motif - - - 0.000002491 55.0
HKD1_k127_351761_3 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 533.0
HKD1_k127_351761_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 435.0
HKD1_k127_351761_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 416.0
HKD1_k127_351761_6 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 380.0
HKD1_k127_351761_7 PFAM Metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 317.0
HKD1_k127_351761_8 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008881 317.0
HKD1_k127_351761_9 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 318.0
HKD1_k127_353775_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.33e-279 869.0
HKD1_k127_353775_1 PFAM AMP-dependent synthetase and ligase - - - 7.213e-245 766.0
HKD1_k127_353775_10 sequence-specific DNA binding K03718 - - 0.000000000000000000000000002696 127.0
HKD1_k127_353775_11 - - - - 0.000000000000000000000001855 104.0
HKD1_k127_353775_12 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.000000000000000000000003832 119.0
HKD1_k127_353775_13 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000001059 95.0
HKD1_k127_353775_14 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000003091 96.0
HKD1_k127_353775_15 PFAM Transglycosylase associated protein - - - 0.000000000000005684 88.0
HKD1_k127_353775_16 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000002685 68.0
HKD1_k127_353775_17 Protein of unknown function VcgC/VcgE (DUF2780) - - - 0.0000000006462 68.0
HKD1_k127_353775_18 Low molecular weight phosphatase family K03741 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 0.0007327 51.0
HKD1_k127_353775_2 Sodium Bile acid symporter family K03325 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 560.0
HKD1_k127_353775_3 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 418.0
HKD1_k127_353775_4 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 361.0
HKD1_k127_353775_5 dehydrogenase and related dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002498 282.0
HKD1_k127_353775_6 Methyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000006826 221.0
HKD1_k127_353775_7 EamA-like transporter family K15270 - - 0.000000000000000000000000000000000000000000000000000001579 204.0
HKD1_k127_353775_8 Protein of unknown function (DUF3830) - - - 0.000000000000000000000000000000000000000004198 164.0
HKD1_k127_353775_9 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.000000000000000000000000000000000000767 149.0
HKD1_k127_37773_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 3.814e-260 821.0
HKD1_k127_37773_1 'PFAM Alpha amylase, catalytic K01187 - 3.2.1.20 6.256e-222 706.0
HKD1_k127_37773_10 Amino-transferase class IV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 402.0
HKD1_k127_37773_11 Thioesterase-like superfamily K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 384.0
HKD1_k127_37773_12 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 376.0
HKD1_k127_37773_13 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 377.0
HKD1_k127_37773_14 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 372.0
HKD1_k127_37773_15 conserved protein (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 373.0
HKD1_k127_37773_16 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 334.0
HKD1_k127_37773_17 Belongs to the UbiD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 334.0
HKD1_k127_37773_18 membrane K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 325.0
HKD1_k127_37773_19 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 320.0
HKD1_k127_37773_2 Mur ligase family, catalytic domain K02558 - 6.3.2.45 1.27e-208 677.0
HKD1_k127_37773_20 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 301.0
HKD1_k127_37773_21 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000006079 272.0
HKD1_k127_37773_22 short-chain dehydrogenase K00059,K18337 - 1.1.1.100,1.1.1.173,1.1.1.377,1.1.1.378 0.0000000000000000000000000000000000000000000000000000000000000000000000000001378 285.0
HKD1_k127_37773_23 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003876 261.0
HKD1_k127_37773_24 Evidence 4 Homologs of previously reported genes of K09927 - - 0.00000000000000000000000000000000000000000000000000000000000002382 238.0
HKD1_k127_37773_25 Pyroglutamyl peptidase K01304 - 3.4.19.3 0.0000000000000000000000000000000000000000000000000000000003375 213.0
HKD1_k127_37773_26 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.000000000000000000000000000000000000000000000000000001369 196.0
HKD1_k127_37773_27 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000006005 188.0
HKD1_k127_37773_28 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000003078 193.0
HKD1_k127_37773_3 von Willebrand factor (vWF) type A domain - - - 3.416e-201 647.0
HKD1_k127_37773_30 PFAM Cupin 2 conserved barrel domain protein K21700 - - 0.000000000000000000000000000001946 138.0
HKD1_k127_37773_31 Tetratricopeptide repeat - - - 0.0000000000000000000000000001764 128.0
HKD1_k127_37773_32 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000001592 107.0
HKD1_k127_37773_33 PFAM DinB family protein - - - 0.000000000000000000007103 108.0
HKD1_k127_37773_35 Sortase family - - - 0.00004383 55.0
HKD1_k127_37773_4 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 601.0
HKD1_k127_37773_5 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 535.0
HKD1_k127_37773_6 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 517.0
HKD1_k127_37773_7 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 523.0
HKD1_k127_37773_8 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 477.0
HKD1_k127_37773_9 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 441.0
HKD1_k127_3936659_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 4.671e-235 758.0
HKD1_k127_3936659_1 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 600.0
HKD1_k127_3936659_10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001458 271.0
HKD1_k127_3936659_11 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001413 267.0
HKD1_k127_3936659_12 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000008251 259.0
HKD1_k127_3936659_13 Anp1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004803 257.0
HKD1_k127_3936659_14 Alpha-1,3-mannosyl-glycoprotein K00726 GO:0003674,GO:0003824,GO:0003827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005794,GO:0005802,GO:0006464,GO:0006486,GO:0006491,GO:0006807,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009628,GO:0009987,GO:0012505,GO:0016262,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0031410,GO:0031982,GO:0031984,GO:0034645,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0070085,GO:0071704,GO:0097708,GO:0098791,GO:0140096,GO:0140103,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.101 0.0000000000000000000000000000000000000000000000000000000000000000007728 252.0
HKD1_k127_3936659_15 Glycosyltransferase family 10 (fucosyltransferase) C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000003151 249.0
HKD1_k127_3936659_16 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000005648 238.0
HKD1_k127_3936659_17 Glycosyl transferases group 1 K20444 - - 0.00000000000000000000000000000000000000000007737 183.0
HKD1_k127_3936659_18 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000004215 169.0
HKD1_k127_3936659_19 COGs COG0569 K transport systems NAD-binding component K03499,K10716 - - 0.000000000000000000000000000000000000005589 149.0
HKD1_k127_3936659_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 561.0
HKD1_k127_3936659_20 self proteolysis - - - 0.000000000000000000002972 104.0
HKD1_k127_3936659_22 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00002103 56.0
HKD1_k127_3936659_3 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 408.0
HKD1_k127_3936659_4 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 382.0
HKD1_k127_3936659_5 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 365.0
HKD1_k127_3936659_6 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 372.0
HKD1_k127_3936659_7 amino acid K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 346.0
HKD1_k127_3936659_8 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 345.0
HKD1_k127_3936659_9 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 314.0
HKD1_k127_3991212_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.851e-277 860.0
HKD1_k127_3991212_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 444.0
HKD1_k127_3991212_10 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.00000000000000000000004982 114.0
HKD1_k127_3991212_11 Mut7-C ubiquitin - - - 0.000000000002088 70.0
HKD1_k127_3991212_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 447.0
HKD1_k127_3991212_3 TRAP-type C4-dicarboxylate transport system periplasmic component K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 375.0
HKD1_k127_3991212_4 PFAM Transketolase K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 356.0
HKD1_k127_3991212_5 Dehydrogenase E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 342.0
HKD1_k127_3991212_6 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000565 286.0
HKD1_k127_3991212_7 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000003335 251.0
HKD1_k127_3991212_8 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000001476 213.0
HKD1_k127_3991212_9 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000002558 205.0
HKD1_k127_4020834_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009165 550.0
HKD1_k127_4020834_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 485.0
HKD1_k127_4020834_10 PFAM response regulator receiver K11443 - - 0.000000000000000000000000000000008589 132.0
HKD1_k127_4020834_11 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000001527 128.0
HKD1_k127_4020834_12 ABC transporter substrate binding protein K01989 - - 0.000000000002632 74.0
HKD1_k127_4020834_2 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 376.0
HKD1_k127_4020834_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004244 285.0
HKD1_k127_4020834_4 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000004149 251.0
HKD1_k127_4020834_5 Nitrile hydratase, alpha chain - - - 0.000000000000000000000000000000000000000000000000000000000000000002017 236.0
HKD1_k127_4020834_6 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000001503 214.0
HKD1_k127_4020834_8 Nitrile hydratase beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000725 205.0
HKD1_k127_4020834_9 TIGRFAM cobaltochelatase, CobN subunit K02230 - 6.6.1.2 0.0000000000000000000000000000000000000000000000107 182.0
HKD1_k127_40365_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 9.258e-197 624.0
HKD1_k127_40365_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 559.0
HKD1_k127_40365_10 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000006649 249.0
HKD1_k127_40365_11 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000114 265.0
HKD1_k127_40365_12 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000001944 246.0
HKD1_k127_40365_13 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005578 251.0
HKD1_k127_40365_14 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000000000000000117 171.0
HKD1_k127_40365_15 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000003836 179.0
HKD1_k127_40365_16 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000007429 166.0
HKD1_k127_40365_17 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000001659 145.0
HKD1_k127_40365_18 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000006549 130.0
HKD1_k127_40365_19 peptidyl-tyrosine sulfation - - - 0.000000003315 70.0
HKD1_k127_40365_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 473.0
HKD1_k127_40365_20 Staphylococcal nuclease homologues - - - 0.0000001244 64.0
HKD1_k127_40365_21 Sulfotransferase family - - - 0.00001742 58.0
HKD1_k127_40365_3 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 456.0
HKD1_k127_40365_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 401.0
HKD1_k127_40365_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 409.0
HKD1_k127_40365_6 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 381.0
HKD1_k127_40365_7 'ABC-type branched-chain amino acid transport K01999,K11954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 355.0
HKD1_k127_40365_8 transport system permease K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 329.0
HKD1_k127_40365_9 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 325.0
HKD1_k127_4056408_0 GTP-binding protein TypA K06207 - - 3.055e-251 787.0
HKD1_k127_4056408_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 2.002e-206 647.0
HKD1_k127_4056408_10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009038 297.0
HKD1_k127_4056408_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001043 261.0
HKD1_k127_4056408_12 Binding-protein-dependent transport system inner membrane component K11082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000142 249.0
HKD1_k127_4056408_13 molybdate ABC transporter, permease protein K02017,K02018 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000003053 235.0
HKD1_k127_4056408_14 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000001063 244.0
HKD1_k127_4056408_15 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000003223 249.0
HKD1_k127_4056408_16 PFAM Multiple antibiotic resistance (MarC)-related K05595 - - 0.00000000000000000000000000000000000000000000000000000000001555 214.0
HKD1_k127_4056408_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000001715 217.0
HKD1_k127_4056408_18 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K09565 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000000000000000000001705 205.0
HKD1_k127_4056408_19 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000001716 205.0
HKD1_k127_4056408_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 487.0
HKD1_k127_4056408_20 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000005346 184.0
HKD1_k127_4056408_21 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000001561 184.0
HKD1_k127_4056408_22 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000004401 197.0
HKD1_k127_4056408_23 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.000000000000000000000000000000000000000000000007974 198.0
HKD1_k127_4056408_24 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000002279 184.0
HKD1_k127_4056408_25 OmpA family K03640 - - 0.000000000000000000000000000000001758 139.0
HKD1_k127_4056408_26 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000666 126.0
HKD1_k127_4056408_27 Cytochrome c K00413 - - 0.000000000000000000000002358 113.0
HKD1_k127_4056408_28 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000003154 98.0
HKD1_k127_4056408_29 GIY-YIG catalytic domain protein K07461 - - 0.000000000000000000006899 98.0
HKD1_k127_4056408_3 Bacterial extracellular solute-binding protein K11081 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 464.0
HKD1_k127_4056408_30 Outer membrane protein beta-barrel domain - - - 0.00000000000000000001398 106.0
HKD1_k127_4056408_31 - - - - 0.00000000000000005905 90.0
HKD1_k127_4056408_32 Aldose 1-epimerase K01792 - 5.1.3.15 0.0000000001068 70.0
HKD1_k127_4056408_34 - K09794 - - 0.0001312 47.0
HKD1_k127_4056408_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 468.0
HKD1_k127_4056408_5 Belongs to the ABC transporter superfamily K11084 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 446.0
HKD1_k127_4056408_6 Binding-protein-dependent transport system inner membrane component K11083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 357.0
HKD1_k127_4056408_7 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 360.0
HKD1_k127_4056408_8 Belongs to the ABC transporter superfamily K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 318.0
HKD1_k127_4056408_9 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 308.0
HKD1_k127_4057142_0 Predicted Permease Membrane Region - - - 1.451e-259 811.0
HKD1_k127_4057142_1 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000000000004843 173.0
HKD1_k127_4057142_2 - - - - 0.000000002674 60.0
HKD1_k127_4057142_3 Domain of unknown function (DUF4136) - - - 0.0001924 52.0
HKD1_k127_4064370_0 Proton-conducting membrane transporter K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 638.0
HKD1_k127_4064370_1 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 559.0
HKD1_k127_4064370_10 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 452.0
HKD1_k127_4064370_11 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 426.0
HKD1_k127_4064370_12 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 419.0
HKD1_k127_4064370_13 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 409.0
HKD1_k127_4064370_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343,K05573 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 424.0
HKD1_k127_4064370_15 FAE1/Type III polyketide synthase-like protein K16167 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 408.0
HKD1_k127_4064370_16 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 397.0
HKD1_k127_4064370_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 377.0
HKD1_k127_4064370_18 nitrogen compound transport K02033,K13894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 403.0
HKD1_k127_4064370_19 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 370.0
HKD1_k127_4064370_2 NADH-quinone oxidoreductase chain L K00341,K05577 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 555.0
HKD1_k127_4064370_20 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 353.0
HKD1_k127_4064370_21 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 345.0
HKD1_k127_4064370_22 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 349.0
HKD1_k127_4064370_23 glycosyl transferase group 1 K08256,K16150 - 2.4.1.11,2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 338.0
HKD1_k127_4064370_24 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 344.0
HKD1_k127_4064370_25 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 313.0
HKD1_k127_4064370_26 response regulator, receiver K02483,K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 287.0
HKD1_k127_4064370_27 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000007168 259.0
HKD1_k127_4064370_28 NIPSNAP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005812 243.0
HKD1_k127_4064370_29 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007028 261.0
HKD1_k127_4064370_3 ABC-Type Dipeptide Transport System Periplasmic Component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008921 524.0
HKD1_k127_4064370_30 Epimerase dehydratase K01784,K12454 - 5.1.3.10,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000006339 253.0
HKD1_k127_4064370_31 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000003736 240.0
HKD1_k127_4064370_32 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000002406 238.0
HKD1_k127_4064370_33 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000004143 238.0
HKD1_k127_4064370_34 - - - - 0.0000000000000000000000000000000000000000000000000000000000001059 230.0
HKD1_k127_4064370_35 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000000000000000000009817 224.0
HKD1_k127_4064370_36 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001504 211.0
HKD1_k127_4064370_37 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000001752 212.0
HKD1_k127_4064370_38 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000001329 197.0
HKD1_k127_4064370_39 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000002739 198.0
HKD1_k127_4064370_4 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 497.0
HKD1_k127_4064370_40 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000001048 182.0
HKD1_k127_4064370_41 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000002934 172.0
HKD1_k127_4064370_42 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000006587 166.0
HKD1_k127_4064370_43 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000001004 163.0
HKD1_k127_4064370_44 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000001682 151.0
HKD1_k127_4064370_45 polyketide synthase K15670 - - 0.0000000000000000000000000000000005707 149.0
HKD1_k127_4064370_46 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000008143 138.0
HKD1_k127_4064370_47 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000003296 138.0
HKD1_k127_4064370_48 4Fe-4S dicluster domain K00338,K02573,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3,1.6.99.3 0.000000000000000000000000000001409 129.0
HKD1_k127_4064370_49 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000001171 119.0
HKD1_k127_4064370_5 Aldehyde dehydrogenase family K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 489.0
HKD1_k127_4064370_50 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000003636 122.0
HKD1_k127_4064370_51 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.0000000000000000000000000001632 130.0
HKD1_k127_4064370_52 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000001245 124.0
HKD1_k127_4064370_53 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.000000000000000000000000001299 117.0
HKD1_k127_4064370_54 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000003884 108.0
HKD1_k127_4064370_55 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.0000000000000000000000004475 111.0
HKD1_k127_4064370_56 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000002805 116.0
HKD1_k127_4064370_57 Chromate transporter K07240 - - 0.000000000000000000000005652 118.0
HKD1_k127_4064370_59 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000001239 106.0
HKD1_k127_4064370_6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 462.0
HKD1_k127_4064370_60 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.00000000000000000000001404 112.0
HKD1_k127_4064370_61 PFAM CBS domain containing protein - - - 0.00000000000000000000004276 106.0
HKD1_k127_4064370_62 PFAM Chromate transporter K07240 - - 0.00000000000000000000006271 108.0
HKD1_k127_4064370_63 pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000002133 104.0
HKD1_k127_4064370_64 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000003298 99.0
HKD1_k127_4064370_65 Polysaccharide biosynthesis protein - - - 0.0000000000000000003403 100.0
HKD1_k127_4064370_66 Preprotein translocase SecG subunit K03075 - - 0.00000000000000005034 84.0
HKD1_k127_4064370_67 YXWGXW repeat (2 copies) - - - 0.000000000001187 76.0
HKD1_k127_4064370_68 Belongs to the 'phage' integrase family - - - 0.0004021 47.0
HKD1_k127_4064370_7 NAD binding K00333,K05579,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 446.0
HKD1_k127_4064370_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 448.0
HKD1_k127_4064370_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 454.0
HKD1_k127_4076592_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.742e-291 921.0
HKD1_k127_4076592_1 Carbamoyltransferase C-terminus K00612 - - 7.295e-263 832.0
HKD1_k127_4076592_10 metallopeptidase activity K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 492.0
HKD1_k127_4076592_11 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 484.0
HKD1_k127_4076592_12 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 485.0
HKD1_k127_4076592_13 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 477.0
HKD1_k127_4076592_14 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 468.0
HKD1_k127_4076592_15 PFAM NAD-dependent epimerase dehydratase K01784,K10011,K12449 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 394.0
HKD1_k127_4076592_16 PFAM Na Picotransporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 384.0
HKD1_k127_4076592_17 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 370.0
HKD1_k127_4076592_18 Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 343.0
HKD1_k127_4076592_19 GDP-mannose 4,6 dehydratase K17947 - 5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 349.0
HKD1_k127_4076592_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.51e-205 668.0
HKD1_k127_4076592_20 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 343.0
HKD1_k127_4076592_21 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 359.0
HKD1_k127_4076592_22 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 338.0
HKD1_k127_4076592_23 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 336.0
HKD1_k127_4076592_24 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 310.0
HKD1_k127_4076592_25 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 301.0
HKD1_k127_4076592_26 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000181 268.0
HKD1_k127_4076592_27 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001662 283.0
HKD1_k127_4076592_28 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000001996 244.0
HKD1_k127_4076592_29 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000149 235.0
HKD1_k127_4076592_3 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 1.131e-197 654.0
HKD1_k127_4076592_30 - - - - 0.000000000000000000000000000000000000000000000000000000000000003867 239.0
HKD1_k127_4076592_31 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000001657 231.0
HKD1_k127_4076592_32 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000004328 228.0
HKD1_k127_4076592_33 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000003854 230.0
HKD1_k127_4076592_34 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000008058 212.0
HKD1_k127_4076592_35 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000000000000000000006652 202.0
HKD1_k127_4076592_36 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000001961 195.0
HKD1_k127_4076592_37 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000005802 189.0
HKD1_k127_4076592_38 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000008166 188.0
HKD1_k127_4076592_39 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000007023 181.0
HKD1_k127_4076592_4 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 616.0
HKD1_k127_4076592_40 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000305 183.0
HKD1_k127_4076592_41 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000003789 180.0
HKD1_k127_4076592_42 phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000002823 162.0
HKD1_k127_4076592_43 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000003355 149.0
HKD1_k127_4076592_44 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000187 138.0
HKD1_k127_4076592_45 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000004118 134.0
HKD1_k127_4076592_46 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000001083 137.0
HKD1_k127_4076592_47 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000021 133.0
HKD1_k127_4076592_48 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000000007154 113.0
HKD1_k127_4076592_49 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000007557 123.0
HKD1_k127_4076592_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 531.0
HKD1_k127_4076592_50 DUF218 domain - - - 0.0000000000000000000007965 111.0
HKD1_k127_4076592_51 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000003033 102.0
HKD1_k127_4076592_52 lipolytic protein G-D-S-L family - - - 0.000000000000002798 89.0
HKD1_k127_4076592_53 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000716 79.0
HKD1_k127_4076592_54 - - - - 0.000000000008513 73.0
HKD1_k127_4076592_55 - - - - 0.00000000002012 70.0
HKD1_k127_4076592_56 Methyltransferase K00568 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.1.1.222,2.1.1.64 0.00000000034 72.0
HKD1_k127_4076592_57 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000001847 70.0
HKD1_k127_4076592_58 RecX family K03565 - - 0.000000005324 64.0
HKD1_k127_4076592_59 Polysaccharide deacetylase - - - 0.0000003503 63.0
HKD1_k127_4076592_6 Ftsk_gamma K03466 GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 527.0
HKD1_k127_4076592_60 Sulfotransferase domain - - - 0.00000277 58.0
HKD1_k127_4076592_61 - - - - 0.000297 54.0
HKD1_k127_4076592_7 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 516.0
HKD1_k127_4076592_8 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 497.0
HKD1_k127_4076592_9 Male sterility protein K12454 - 5.1.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 513.0
HKD1_k127_4126046_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 606.0
HKD1_k127_4126046_1 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 471.0
HKD1_k127_4126046_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000005943 181.0
HKD1_k127_4126046_11 cyclic diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000007062 183.0
HKD1_k127_4126046_12 C-terminal domain of histone - - - 0.00000000000000000000000000000000000000001608 169.0
HKD1_k127_4126046_13 methyltransferase K15256 - - 0.000000000000000000000000000000000000001237 154.0
HKD1_k127_4126046_14 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000069 121.0
HKD1_k127_4126046_15 Domain of unknown function (DUF1844) - - - 0.0000000000000001861 87.0
HKD1_k127_4126046_16 diguanylate cyclase - - - 0.00000000000003985 79.0
HKD1_k127_4126046_17 cheY-homologous receiver domain K03413 - - 0.0000000000001111 83.0
HKD1_k127_4126046_18 Belongs to the N-Me-Phe pilin family K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00000003274 62.0
HKD1_k127_4126046_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 430.0
HKD1_k127_4126046_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 380.0
HKD1_k127_4126046_4 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 375.0
HKD1_k127_4126046_5 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000005841 277.0
HKD1_k127_4126046_6 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000506 294.0
HKD1_k127_4126046_7 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000005078 215.0
HKD1_k127_4126046_8 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000001688 200.0
HKD1_k127_4126046_9 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000003028 189.0
HKD1_k127_4127928_0 PFAM aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 1.829e-304 964.0
HKD1_k127_4127928_1 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 591.0
HKD1_k127_4127928_10 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000003737 139.0
HKD1_k127_4127928_11 Cadherin repeats. - - - 0.00000089 61.0
HKD1_k127_4127928_2 PFAM peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 571.0
HKD1_k127_4127928_3 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 481.0
HKD1_k127_4127928_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 369.0
HKD1_k127_4127928_5 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 331.0
HKD1_k127_4127928_6 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 306.0
HKD1_k127_4127928_7 Phosphatidylinositol - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001143 251.0
HKD1_k127_4127928_8 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000000000000003839 248.0
HKD1_k127_4127928_9 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000001355 216.0
HKD1_k127_4214003_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.213e-277 871.0
HKD1_k127_4214003_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 617.0
HKD1_k127_4214003_10 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 454.0
HKD1_k127_4214003_11 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 454.0
HKD1_k127_4214003_12 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 436.0
HKD1_k127_4214003_13 Rieske 2Fe-2S domain protein K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 440.0
HKD1_k127_4214003_14 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 422.0
HKD1_k127_4214003_15 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 380.0
HKD1_k127_4214003_16 major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 386.0
HKD1_k127_4214003_17 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 368.0
HKD1_k127_4214003_18 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 354.0
HKD1_k127_4214003_19 trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 321.0
HKD1_k127_4214003_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 599.0
HKD1_k127_4214003_20 N-terminal TM domain of oligopeptide transport permease C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 319.0
HKD1_k127_4214003_21 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 289.0
HKD1_k127_4214003_22 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004873 269.0
HKD1_k127_4214003_23 hydrolase, family 3 K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000001408 267.0
HKD1_k127_4214003_24 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000005575 246.0
HKD1_k127_4214003_25 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000002119 237.0
HKD1_k127_4214003_26 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000001297 233.0
HKD1_k127_4214003_27 Nudix hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000002815 216.0
HKD1_k127_4214003_28 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000627 192.0
HKD1_k127_4214003_29 Dihydrodipicolinate synthetase family K01639,K01714 - 4.1.3.3,4.3.3.7 0.0000000000000000000000000000000000000000000000009588 186.0
HKD1_k127_4214003_3 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 609.0
HKD1_k127_4214003_30 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000009704 169.0
HKD1_k127_4214003_31 - - - - 0.000000000000000000000000000000000000000001587 159.0
HKD1_k127_4214003_32 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000001552 167.0
HKD1_k127_4214003_33 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000154 151.0
HKD1_k127_4214003_34 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000002185 96.0
HKD1_k127_4214003_35 - - - - 0.00000000000000861 83.0
HKD1_k127_4214003_4 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 579.0
HKD1_k127_4214003_5 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 561.0
HKD1_k127_4214003_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15785 - 2.6.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 558.0
HKD1_k127_4214003_7 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 562.0
HKD1_k127_4214003_8 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 476.0
HKD1_k127_4214003_9 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 470.0
HKD1_k127_4252280_0 Proteasomal ATPase OB/ID domain K07184,K07777,K12065,K13525,K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 2.7.13.3 7.559e-238 751.0
HKD1_k127_4252280_1 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 607.0
HKD1_k127_4252280_10 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006824 275.0
HKD1_k127_4252280_11 transcription activator K03707 - 3.5.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001717 275.0
HKD1_k127_4252280_12 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000003497 248.0
HKD1_k127_4252280_13 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006143 247.0
HKD1_k127_4252280_14 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000126 247.0
HKD1_k127_4252280_15 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000002324 166.0
HKD1_k127_4252280_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000002865 143.0
HKD1_k127_4252280_17 Putative zinc-finger - - - 0.00000000000000000000000000001496 133.0
HKD1_k127_4252280_18 Histidine phosphatase superfamily (branch 1) K03574,K08296 - 3.6.1.55 0.00000000000000000008225 102.0
HKD1_k127_4252280_19 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000001554 83.0
HKD1_k127_4252280_2 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 592.0
HKD1_k127_4252280_20 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000005182 73.0
HKD1_k127_4252280_21 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000003315 59.0
HKD1_k127_4252280_22 ABC transporter substrate-binding protein K02027 - - 0.0000002415 58.0
HKD1_k127_4252280_3 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 518.0
HKD1_k127_4252280_4 TOBE domain K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 487.0
HKD1_k127_4252280_5 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 489.0
HKD1_k127_4252280_6 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 460.0
HKD1_k127_4252280_7 Proteasome subunit K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 335.0
HKD1_k127_4252280_8 Short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 297.0
HKD1_k127_4252280_9 Proteasome subunit K03432 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 287.0
HKD1_k127_4305034_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 1.468e-270 855.0
HKD1_k127_4305034_1 AMP-binding enzyme C-terminal domain K00666 - - 1.048e-258 806.0
HKD1_k127_4305034_10 Belongs to the HAD-like hydrolase superfamily. PhnX family K05306 - 3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 422.0
HKD1_k127_4305034_11 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 352.0
HKD1_k127_4305034_12 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 321.0
HKD1_k127_4305034_13 SMP-30/Gluconolaconase/LRE-like region K13874,K14274 - 3.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 315.0
HKD1_k127_4305034_14 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005325 299.0
HKD1_k127_4305034_15 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002039 258.0
HKD1_k127_4305034_16 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000006133 256.0
HKD1_k127_4305034_17 mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.0000000000000000000000000000000000000000000000000000000000000000001722 245.0
HKD1_k127_4305034_18 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000001846 212.0
HKD1_k127_4305034_19 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000002234 218.0
HKD1_k127_4305034_2 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 554.0
HKD1_k127_4305034_20 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000008467 205.0
HKD1_k127_4305034_21 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000172 180.0
HKD1_k127_4305034_22 Belongs to the HpcH HpaI aldolase family K00979,K02510 - 2.7.7.38,4.1.2.52 0.00000000000000000000000000000000000000000009542 186.0
HKD1_k127_4305034_23 PFAM Sodium sulfate symporter transmembrane region K03319 - - 0.00000000000000000000000000000000000002694 166.0
HKD1_k127_4305034_24 Serine aminopeptidase, S33 K19311 GO:0003674,GO:0003824,GO:0005488,GO:0005504,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016298,GO:0016787,GO:0016788,GO:0019752,GO:0031406,GO:0032787,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0072329,GO:0104004,GO:1901575 - 0.00000000000000000000000000000000678 140.0
HKD1_k127_4305034_25 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000001651 145.0
HKD1_k127_4305034_27 phosphatase activity K07025 - - 0.000000000000000000003736 109.0
HKD1_k127_4305034_28 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000003271 95.0
HKD1_k127_4305034_29 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000001481 90.0
HKD1_k127_4305034_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 561.0
HKD1_k127_4305034_30 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000001903 91.0
HKD1_k127_4305034_31 Tautomerase enzyme - - - 0.00000000006988 67.0
HKD1_k127_4305034_32 peroxiredoxin activity K02199 - - 0.000000000594 66.0
HKD1_k127_4305034_33 Ribonuclease HI K03469,K06993 - 3.1.26.4 0.00000004608 66.0
HKD1_k127_4305034_34 AhpC/TSA antioxidant enzyme - - - 0.0002844 47.0
HKD1_k127_4305034_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 544.0
HKD1_k127_4305034_5 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 487.0
HKD1_k127_4305034_6 PFAM Mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 474.0
HKD1_k127_4305034_7 Aldo/keto reductase family K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 447.0
HKD1_k127_4305034_8 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 445.0
HKD1_k127_4305034_9 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K19837 - 3.5.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007587 449.0
HKD1_k127_4307778_0 aminopeptidase K01262 - 3.4.11.9 4.074e-242 775.0
HKD1_k127_4307778_1 Peptidase family M1 domain K08776 - - 8.546e-231 745.0
HKD1_k127_4307778_10 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 493.0
HKD1_k127_4307778_100 - - - - 0.000000000000000003547 97.0
HKD1_k127_4307778_101 endonuclease exonuclease phosphatase - - - 0.00000000000000000421 99.0
HKD1_k127_4307778_102 YceI-like domain - - - 0.0000000000000004857 90.0
HKD1_k127_4307778_103 Acetyltransferase (GNAT) domain - - - 0.00000000000001199 82.0
HKD1_k127_4307778_104 Cupin domain - - - 0.00000000000003914 81.0
HKD1_k127_4307778_105 - - - - 0.0000000001016 66.0
HKD1_k127_4307778_107 Thermophilic metalloprotease (M29) - - - 0.00000009824 64.0
HKD1_k127_4307778_108 Protein involved in outer membrane biogenesis - - - 0.0000004583 63.0
HKD1_k127_4307778_109 DoxX K15977 - - 0.0000006632 58.0
HKD1_k127_4307778_11 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 475.0
HKD1_k127_4307778_110 - - - - 0.0000008978 54.0
HKD1_k127_4307778_111 - - - - 0.000001419 58.0
HKD1_k127_4307778_112 Short-chain dehydrogenase reductase sdr - - - 0.000005996 56.0
HKD1_k127_4307778_113 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 0.0002902 47.0
HKD1_k127_4307778_12 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 487.0
HKD1_k127_4307778_13 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 479.0
HKD1_k127_4307778_14 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 469.0
HKD1_k127_4307778_15 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 454.0
HKD1_k127_4307778_16 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 459.0
HKD1_k127_4307778_17 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 452.0
HKD1_k127_4307778_18 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 434.0
HKD1_k127_4307778_19 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 449.0
HKD1_k127_4307778_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.305e-217 700.0
HKD1_k127_4307778_20 formamidase K01455 - 3.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 439.0
HKD1_k127_4307778_21 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 437.0
HKD1_k127_4307778_22 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 430.0
HKD1_k127_4307778_23 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 427.0
HKD1_k127_4307778_24 Amidohydrolase family K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 421.0
HKD1_k127_4307778_25 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008906 406.0
HKD1_k127_4307778_26 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 400.0
HKD1_k127_4307778_27 COG0001 Glutamate-1-semialdehyde aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 382.0
HKD1_k127_4307778_28 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 374.0
HKD1_k127_4307778_29 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 383.0
HKD1_k127_4307778_3 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 617.0
HKD1_k127_4307778_30 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 394.0
HKD1_k127_4307778_31 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 377.0
HKD1_k127_4307778_32 MlrC C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 388.0
HKD1_k127_4307778_33 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 360.0
HKD1_k127_4307778_34 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 361.0
HKD1_k127_4307778_35 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 344.0
HKD1_k127_4307778_36 TOBE domain K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 331.0
HKD1_k127_4307778_37 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 339.0
HKD1_k127_4307778_38 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007594 334.0
HKD1_k127_4307778_39 High-affinity nickel-transport protein K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 316.0
HKD1_k127_4307778_4 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 601.0
HKD1_k127_4307778_40 Extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 327.0
HKD1_k127_4307778_41 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 314.0
HKD1_k127_4307778_42 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 328.0
HKD1_k127_4307778_43 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 318.0
HKD1_k127_4307778_44 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 307.0
HKD1_k127_4307778_45 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 302.0
HKD1_k127_4307778_46 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 313.0
HKD1_k127_4307778_47 Protein of unknown function (DUF3750) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 301.0
HKD1_k127_4307778_48 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 318.0
HKD1_k127_4307778_49 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 299.0
HKD1_k127_4307778_5 Aminotransferase class-V K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 565.0
HKD1_k127_4307778_50 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 312.0
HKD1_k127_4307778_51 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 291.0
HKD1_k127_4307778_52 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 289.0
HKD1_k127_4307778_53 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 289.0
HKD1_k127_4307778_54 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 293.0
HKD1_k127_4307778_55 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000667 288.0
HKD1_k127_4307778_56 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001309 295.0
HKD1_k127_4307778_57 Iron ABC transporter substrate-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001429 281.0
HKD1_k127_4307778_58 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002288 277.0
HKD1_k127_4307778_59 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000415 292.0
HKD1_k127_4307778_6 acetamidase formamidase K01455 - 3.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 561.0
HKD1_k127_4307778_60 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001585 265.0
HKD1_k127_4307778_61 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004204 263.0
HKD1_k127_4307778_62 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004357 263.0
HKD1_k127_4307778_63 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001073 264.0
HKD1_k127_4307778_64 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003376 274.0
HKD1_k127_4307778_65 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004171 265.0
HKD1_k127_4307778_66 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004028 265.0
HKD1_k127_4307778_67 extracellular solute-binding K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002907 261.0
HKD1_k127_4307778_68 COGs COG0747 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000384 262.0
HKD1_k127_4307778_69 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000007503 240.0
HKD1_k127_4307778_7 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 539.0
HKD1_k127_4307778_70 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000002951 239.0
HKD1_k127_4307778_71 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.000000000000000000000000000000000000000000000000000000000000000008564 231.0
HKD1_k127_4307778_72 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000002178 234.0
HKD1_k127_4307778_73 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000002618 220.0
HKD1_k127_4307778_74 Metal-binding integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000002126 218.0
HKD1_k127_4307778_75 Choline ethanolamine kinase - - - 0.000000000000000000000000000000000000000000000000000000005032 222.0
HKD1_k127_4307778_76 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000001401 219.0
HKD1_k127_4307778_77 Responsible for synthesis of pseudouridine from uracil K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000006243 203.0
HKD1_k127_4307778_78 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000000008286 217.0
HKD1_k127_4307778_79 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000001858 199.0
HKD1_k127_4307778_8 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 545.0
HKD1_k127_4307778_80 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000007544 190.0
HKD1_k127_4307778_81 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000004606 201.0
HKD1_k127_4307778_82 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000002399 193.0
HKD1_k127_4307778_83 haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K07025 - - 0.000000000000000000000000000000000000000000000003704 198.0
HKD1_k127_4307778_84 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000004769 186.0
HKD1_k127_4307778_85 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000002716 186.0
HKD1_k127_4307778_86 KR domain K07535 - - 0.000000000000000000000000000000000000000000003788 172.0
HKD1_k127_4307778_87 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000001014 173.0
HKD1_k127_4307778_88 Isochorismatase family K09020 - 3.5.1.110 0.00000000000000000000000000000000000000000001375 178.0
HKD1_k127_4307778_89 dehydratase - - - 0.00000000000000000000000000000000000000000002528 177.0
HKD1_k127_4307778_9 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 505.0
HKD1_k127_4307778_90 Dolichyl-phosphate-mannose-protein mannosyltransferase - GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000004064 185.0
HKD1_k127_4307778_91 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000408 177.0
HKD1_k127_4307778_92 Pfam:TPM K08988 - - 0.00000000000000000000000000000000000002381 162.0
HKD1_k127_4307778_93 EamA-like transporter family - - - 0.00000000000000000000000000000000001479 150.0
HKD1_k127_4307778_94 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000004479 151.0
HKD1_k127_4307778_95 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000003332 138.0
HKD1_k127_4307778_96 Cys-tRNA(Pro) hydrolase activity K03976 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000003497 130.0
HKD1_k127_4307778_97 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.0000000000000000000000000000005653 141.0
HKD1_k127_4307778_98 PFAM Cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000006829 137.0
HKD1_k127_4307778_99 Pfam:DUF385 - - - 0.0000000000000000001135 94.0
HKD1_k127_4395340_0 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 437.0
HKD1_k127_4395340_1 Ethylbenzene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 416.0
HKD1_k127_4395340_2 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 397.0
HKD1_k127_4395340_3 Cytochrome c - - - 0.0000000000000000000000000000000000000334 155.0
HKD1_k127_4395340_4 protein histidine kinase activity K06375 - - 0.0000000000000000004064 98.0
HKD1_k127_4428646_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 486.0
HKD1_k127_4428646_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000006123 239.0
HKD1_k127_4428646_2 4Fe-4S binding domain K05524 - - 0.000000000000000000000000000000000001803 141.0
HKD1_k127_4428646_3 - - - - 0.00000000000000000000000000000002442 132.0
HKD1_k127_4428646_4 Transcriptional regulatory protein, C terminal K11329 - - 0.00000000000000004803 96.0
HKD1_k127_444933_0 Bacterial extracellular solute-binding protein K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 404.0
HKD1_k127_444933_1 PFAM Binding-protein-dependent transport system inner membrane component K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 308.0
HKD1_k127_444933_2 COG1175 ABC-type sugar transport systems permease components K05814 - - 0.00000000000000000000000000000000000000000000000000000000002157 215.0
HKD1_k127_444933_3 - - - - 0.000000006834 68.0
HKD1_k127_452745_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.609e-265 838.0
HKD1_k127_452745_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.3e-239 762.0
HKD1_k127_452745_10 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 469.0
HKD1_k127_452745_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 448.0
HKD1_k127_452745_12 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009786 411.0
HKD1_k127_452745_13 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 391.0
HKD1_k127_452745_14 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 363.0
HKD1_k127_452745_15 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 351.0
HKD1_k127_452745_16 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 302.0
HKD1_k127_452745_17 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000131 256.0
HKD1_k127_452745_18 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000002816 251.0
HKD1_k127_452745_19 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000002161 246.0
HKD1_k127_452745_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.689e-235 742.0
HKD1_k127_452745_20 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000003947 243.0
HKD1_k127_452745_21 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000027 232.0
HKD1_k127_452745_22 - - - - 0.00000000000000000000000000000000000000000000000000000001807 212.0
HKD1_k127_452745_23 CoA-transferase family III K18703 - 2.8.3.13 0.000000000000000000000000000000000000000000000000000001936 199.0
HKD1_k127_452745_24 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000007783 199.0
HKD1_k127_452745_25 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000003316 182.0
HKD1_k127_452745_26 B12 binding domain - - - 0.00000000000000000000000000000000000000000006912 164.0
HKD1_k127_452745_27 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000132 170.0
HKD1_k127_452745_28 - - - - 0.00000000000000000000000000000000000001344 154.0
HKD1_k127_452745_29 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000003968 137.0
HKD1_k127_452745_3 Voltage gated chloride channel - - - 3.074e-231 737.0
HKD1_k127_452745_30 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000007957 128.0
HKD1_k127_452745_31 Tetratricopeptide repeat - - - 0.00000000000000000000000000002532 137.0
HKD1_k127_452745_32 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000002769 118.0
HKD1_k127_452745_33 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000001715 100.0
HKD1_k127_452745_34 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000007396 97.0
HKD1_k127_452745_4 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.139e-223 709.0
HKD1_k127_452745_5 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 619.0
HKD1_k127_452745_6 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 572.0
HKD1_k127_452745_7 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 574.0
HKD1_k127_452745_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 522.0
HKD1_k127_452745_9 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 475.0
HKD1_k127_4599413_0 Fe-S oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 578.0
HKD1_k127_4599413_1 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 421.0
HKD1_k127_4599413_2 GTPase activity K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 307.0
HKD1_k127_4599413_3 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000007593 138.0
HKD1_k127_4599413_4 Cytochrome C' - - - 0.000000000001819 74.0
HKD1_k127_4599413_5 Cytochrome c, mono- and diheme variants - - - 0.0008562 43.0
HKD1_k127_4618326_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1105.0
HKD1_k127_4618326_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 3.402e-252 821.0
HKD1_k127_4618326_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 571.0
HKD1_k127_4618326_11 Belongs to the ABC transporter superfamily K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 490.0
HKD1_k127_4618326_12 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 489.0
HKD1_k127_4618326_13 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 458.0
HKD1_k127_4618326_14 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 437.0
HKD1_k127_4618326_15 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 457.0
HKD1_k127_4618326_16 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 417.0
HKD1_k127_4618326_17 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009638 385.0
HKD1_k127_4618326_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 411.0
HKD1_k127_4618326_19 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 364.0
HKD1_k127_4618326_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 9.065e-231 729.0
HKD1_k127_4618326_20 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 336.0
HKD1_k127_4618326_21 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 335.0
HKD1_k127_4618326_22 S4 RNA-binding domain K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 296.0
HKD1_k127_4618326_23 COGs COG0647 sugar phosphatase of the HAD superfamily K01101,K02566 - 3.1.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001021 282.0
HKD1_k127_4618326_24 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000001053 234.0
HKD1_k127_4618326_25 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000006683 239.0
HKD1_k127_4618326_26 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000003584 196.0
HKD1_k127_4618326_27 glycerophosphoryl diester phosphodiesterase - - - 0.00000000000000000000000000000000000000000000002448 181.0
HKD1_k127_4618326_28 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.0000000000000000000000000000000000000000003402 180.0
HKD1_k127_4618326_29 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000003045 179.0
HKD1_k127_4618326_3 UvrD/REP helicase N-terminal domain K03656,K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 3.596e-207 666.0
HKD1_k127_4618326_30 ABC transporter K09812 - - 0.000000000000000000000000000000000000006257 153.0
HKD1_k127_4618326_31 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000006932 160.0
HKD1_k127_4618326_32 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000004465 140.0
HKD1_k127_4618326_33 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000005019 128.0
HKD1_k127_4618326_34 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000005108 126.0
HKD1_k127_4618326_35 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000004328 85.0
HKD1_k127_4618326_36 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000003146 93.0
HKD1_k127_4618326_37 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000000000003615 70.0
HKD1_k127_4618326_38 Glycosyl transferase, family 2 - - - 0.00000001427 69.0
HKD1_k127_4618326_39 - - - - 0.00001895 55.0
HKD1_k127_4618326_4 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 4.804e-200 642.0
HKD1_k127_4618326_40 Part of the ABC transporter FtsEX involved in cellular division K09811 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - 0.0000349 55.0
HKD1_k127_4618326_5 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 5.883e-200 632.0
HKD1_k127_4618326_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 614.0
HKD1_k127_4618326_7 PFAM extracellular solute-binding protein family 1 K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 591.0
HKD1_k127_4618326_8 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 597.0
HKD1_k127_4618326_9 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 588.0
HKD1_k127_4759199_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179,K04090 - 1.2.7.8 0.0 1183.0
HKD1_k127_4759199_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 585.0
HKD1_k127_4759199_10 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000004724 271.0
HKD1_k127_4759199_11 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007902 268.0
HKD1_k127_4759199_12 Creatinine amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001338 256.0
HKD1_k127_4759199_13 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002975 273.0
HKD1_k127_4759199_14 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003315 254.0
HKD1_k127_4759199_15 PFAM Dimethylmenaquinone methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004784 247.0
HKD1_k127_4759199_16 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000005804 234.0
HKD1_k127_4759199_17 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000002449 236.0
HKD1_k127_4759199_18 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000000000000000000000000000002125 171.0
HKD1_k127_4759199_19 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000000058 140.0
HKD1_k127_4759199_2 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 414.0
HKD1_k127_4759199_20 Pup-like protein K13570 - - 0.00000000000005184 76.0
HKD1_k127_4759199_21 Regulatory protein, FmdB family - - - 0.0000000004549 63.0
HKD1_k127_4759199_22 Putative zinc-finger - - - 0.0000000006595 72.0
HKD1_k127_4759199_3 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 394.0
HKD1_k127_4759199_4 Extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 410.0
HKD1_k127_4759199_5 Acyl-CoA dehydrogenase, N-terminal domain K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 375.0
HKD1_k127_4759199_6 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 387.0
HKD1_k127_4759199_7 Binding-protein-dependent transport system inner membrane component K02025,K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 328.0
HKD1_k127_4759199_8 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 332.0
HKD1_k127_4759199_9 NAD(P)H quinone oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 323.0
HKD1_k127_5038846_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.257e-290 907.0
HKD1_k127_5038846_1 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 2.44e-280 870.0
HKD1_k127_5038846_10 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009374 418.0
HKD1_k127_5038846_11 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 406.0
HKD1_k127_5038846_12 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 387.0
HKD1_k127_5038846_13 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 368.0
HKD1_k127_5038846_14 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 376.0
HKD1_k127_5038846_15 TonB-dependent Receptor Plug Domain K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 380.0
HKD1_k127_5038846_16 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 366.0
HKD1_k127_5038846_17 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 364.0
HKD1_k127_5038846_18 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 348.0
HKD1_k127_5038846_19 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 336.0
HKD1_k127_5038846_2 Amidohydrolase family K01466 - 3.5.2.5 6.011e-224 704.0
HKD1_k127_5038846_20 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 336.0
HKD1_k127_5038846_21 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 332.0
HKD1_k127_5038846_22 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 336.0
HKD1_k127_5038846_23 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 316.0
HKD1_k127_5038846_24 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 314.0
HKD1_k127_5038846_25 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 309.0
HKD1_k127_5038846_26 Malate/L-lactate dehydrogenase K13574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 309.0
HKD1_k127_5038846_27 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007072 277.0
HKD1_k127_5038846_28 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000108 278.0
HKD1_k127_5038846_29 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001768 266.0
HKD1_k127_5038846_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.095e-205 657.0
HKD1_k127_5038846_30 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000001713 263.0
HKD1_k127_5038846_31 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000005972 258.0
HKD1_k127_5038846_32 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K16843 - 1.1.1.310 0.00000000000000000000000000000000000000000000000000000000000000000001508 252.0
HKD1_k127_5038846_33 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000005031 254.0
HKD1_k127_5038846_34 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000004009 228.0
HKD1_k127_5038846_35 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000004217 252.0
HKD1_k127_5038846_36 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000003867 239.0
HKD1_k127_5038846_37 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.00000000000000000000000000000000000000000000000000000000000004745 227.0
HKD1_k127_5038846_38 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000005067 216.0
HKD1_k127_5038846_39 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000003051 231.0
HKD1_k127_5038846_4 peptidase, M20 - - - 6.798e-195 618.0
HKD1_k127_5038846_40 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000004077 216.0
HKD1_k127_5038846_41 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000463 207.0
HKD1_k127_5038846_42 PFAM ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000001438 215.0
HKD1_k127_5038846_43 metallopeptidase activity K03630 - - 0.000000000000000000000000000000000000000000000000000001729 210.0
HKD1_k127_5038846_44 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000001873 211.0
HKD1_k127_5038846_45 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.00000000000000000000000000000000000000000000000000002142 202.0
HKD1_k127_5038846_46 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000002534 186.0
HKD1_k127_5038846_47 MaoC like domain - - - 0.00000000000000000000000000000000000000000000003646 175.0
HKD1_k127_5038846_48 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000008813 169.0
HKD1_k127_5038846_49 LppP/LprE lipoprotein - - - 0.0000000000000000000000000000000000000000002241 184.0
HKD1_k127_5038846_5 TIGRFAM arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 533.0
HKD1_k127_5038846_50 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000003394 165.0
HKD1_k127_5038846_51 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000004627 165.0
HKD1_k127_5038846_52 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000001448 168.0
HKD1_k127_5038846_53 chlorophyll binding K03286 - - 0.000000000000000000000000000000000000000868 159.0
HKD1_k127_5038846_54 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000005288 162.0
HKD1_k127_5038846_55 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000001323 156.0
HKD1_k127_5038846_56 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000000000000000000000000000000000000364 166.0
HKD1_k127_5038846_57 DoxX K15977 - - 0.000000000000000000000000000000002736 139.0
HKD1_k127_5038846_58 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00226,K00254 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.3.5.2,1.3.98.1 0.0000000000000000000000000000001335 138.0
HKD1_k127_5038846_59 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000001852 134.0
HKD1_k127_5038846_6 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 490.0
HKD1_k127_5038846_60 Major facilitator superfamily - - - 0.0000000000000000000000000000007222 136.0
HKD1_k127_5038846_61 FecR protein - - - 0.0000000000000000000000000000818 122.0
HKD1_k127_5038846_62 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000007724 131.0
HKD1_k127_5038846_63 Predicted integral membrane protein (DUF2282) - - - 0.000000000000000000000000003896 113.0
HKD1_k127_5038846_65 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000002571 116.0
HKD1_k127_5038846_66 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.000000000000000006066 86.0
HKD1_k127_5038846_67 - - - - 0.0000000000000009286 83.0
HKD1_k127_5038846_68 - - - - 0.000000000001937 82.0
HKD1_k127_5038846_69 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000001785 74.0
HKD1_k127_5038846_7 major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 457.0
HKD1_k127_5038846_70 - - - - 0.0000000001397 64.0
HKD1_k127_5038846_72 PFAM YbbR-like protein - - - 0.0000000007885 71.0
HKD1_k127_5038846_73 peptidoglycan binding K02453,K03749 GO:0000910,GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0022402,GO:0030428,GO:0032153,GO:0032506,GO:0042834,GO:0044464,GO:0051301,GO:0097367 - 0.00000001012 66.0
HKD1_k127_5038846_74 Protein of unknown function (DUF1706) - - - 0.00000002433 68.0
HKD1_k127_5038846_75 Asp Glu hydantoin racemase K16841 - 5.1.99.3 0.0000009906 61.0
HKD1_k127_5038846_76 Gram-negative bacterial TonB protein C-terminal - - - 0.0000336 55.0
HKD1_k127_5038846_78 - - - - 0.0001061 54.0
HKD1_k127_5038846_79 YCII-related domain - - - 0.0004424 45.0
HKD1_k127_5038846_8 COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit K00244 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 448.0
HKD1_k127_5038846_80 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.0004807 51.0
HKD1_k127_5038846_9 Chase2 domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 467.0
HKD1_k127_5041076_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1328.0
HKD1_k127_5041076_1 Histidine kinase-like ATPases - - - 0.0 1254.0
HKD1_k127_5041076_10 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 1.216e-225 712.0
HKD1_k127_5041076_100 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001087 247.0
HKD1_k127_5041076_101 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000001198 256.0
HKD1_k127_5041076_102 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000001577 252.0
HKD1_k127_5041076_103 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000001702 235.0
HKD1_k127_5041076_104 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000000000000001338 255.0
HKD1_k127_5041076_105 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000006634 235.0
HKD1_k127_5041076_106 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000001975 229.0
HKD1_k127_5041076_107 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000006932 222.0
HKD1_k127_5041076_108 BON domain K04065 - - 0.00000000000000000000000000000000000000000000000000000000000000095 231.0
HKD1_k127_5041076_109 Vitamin K-dependent gamma-carboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000005602 243.0
HKD1_k127_5041076_11 Belongs to the peptidase S16 family - - - 1.507e-224 726.0
HKD1_k127_5041076_110 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000001503 229.0
HKD1_k127_5041076_111 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000001221 207.0
HKD1_k127_5041076_112 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000002613 228.0
HKD1_k127_5041076_113 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000003939 226.0
HKD1_k127_5041076_114 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000007859 224.0
HKD1_k127_5041076_115 Thioredoxin-like K02199,K03671 - - 0.000000000000000000000000000000000000000000000000000000001126 223.0
HKD1_k127_5041076_116 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000000000000000549 211.0
HKD1_k127_5041076_117 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000006667 201.0
HKD1_k127_5041076_118 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000005098 220.0
HKD1_k127_5041076_119 Adenylate guanylate cyclase catalytic domain protein K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000005123 222.0
HKD1_k127_5041076_12 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 4.314e-222 714.0
HKD1_k127_5041076_120 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000009739 206.0
HKD1_k127_5041076_121 CcmB protein K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.00000000000000000000000000000000000000000000000000002128 198.0
HKD1_k127_5041076_122 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000003289 201.0
HKD1_k127_5041076_123 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000008055 195.0
HKD1_k127_5041076_124 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000009144 186.0
HKD1_k127_5041076_125 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000000000000000000000000000000000004553 180.0
HKD1_k127_5041076_126 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000006349 178.0
HKD1_k127_5041076_127 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000000000000001668 194.0
HKD1_k127_5041076_128 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000002201 176.0
HKD1_k127_5041076_129 PFAM NUDIX domain - - - 0.00000000000000000000000000000000000000000000002477 182.0
HKD1_k127_5041076_13 DNA polymerase X family K02347,K04477 - - 9.03e-216 685.0
HKD1_k127_5041076_130 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000774 183.0
HKD1_k127_5041076_131 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms - - - 0.0000000000000000000000000000000000000000000003329 179.0
HKD1_k127_5041076_132 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000004162 176.0
HKD1_k127_5041076_133 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000001725 179.0
HKD1_k127_5041076_134 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000003381 183.0
HKD1_k127_5041076_135 PFAM CBS domain K04767 - - 0.0000000000000000000000000000000000000000001202 168.0
HKD1_k127_5041076_136 Haem-binding domain - - - 0.0000000000000000000000000000000000000000004046 164.0
HKD1_k127_5041076_137 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000006934 161.0
HKD1_k127_5041076_138 PFAM Acetyltransferase (GNAT) family K18815 - 2.3.1.82 0.000000000000000000000000000000000000000004956 163.0
HKD1_k127_5041076_139 translation release factor activity K03265 - - 0.00000000000000000000000000000000000000002726 172.0
HKD1_k127_5041076_14 FAD dependent oxidoreductase central domain - - - 2.223e-215 697.0
HKD1_k127_5041076_140 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000001292 160.0
HKD1_k127_5041076_141 Universal stress protein family - - - 0.000000000000000000000000000000000000106 153.0
HKD1_k127_5041076_142 Protein of unknown function (DUF3105) - - - 0.000000000000000000000000000000008485 134.0
HKD1_k127_5041076_143 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000001163 140.0
HKD1_k127_5041076_144 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000005106 138.0
HKD1_k127_5041076_145 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000000000404 138.0
HKD1_k127_5041076_146 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000007167 132.0
HKD1_k127_5041076_147 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000002426 126.0
HKD1_k127_5041076_148 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.000000000000000000000000000008797 130.0
HKD1_k127_5041076_149 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000004401 138.0
HKD1_k127_5041076_15 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 1.556e-210 702.0
HKD1_k127_5041076_150 NIPSNAP - - - 0.00000000000000000000000000008186 130.0
HKD1_k127_5041076_151 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000008496 119.0
HKD1_k127_5041076_152 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000004425 112.0
HKD1_k127_5041076_153 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000008046 126.0
HKD1_k127_5041076_154 subunit of a heme lyase K02198,K02200 - - 0.00000000000000000000000006394 121.0
HKD1_k127_5041076_155 CoA binding domain - - - 0.0000000000000000000000008289 111.0
HKD1_k127_5041076_156 Putative nucleotidyltransferase substrate binding domain - - - 0.000000000000000000000001081 108.0
HKD1_k127_5041076_157 COGs COG0589 Universal stress protein UspA and related nucleotide-binding protein - - - 0.000000000000000000000003323 111.0
HKD1_k127_5041076_158 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.000000000000000000000005918 117.0
HKD1_k127_5041076_159 pyridoxamine-phosphate oxidase activity K00275 - 1.4.3.5 0.00000000000000000000003008 111.0
HKD1_k127_5041076_16 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.166e-208 668.0
HKD1_k127_5041076_160 PFAM CBS domain containing protein - - - 0.00000000000000000000009504 108.0
HKD1_k127_5041076_161 - - - - 0.0000000000000000000001107 113.0
HKD1_k127_5041076_162 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000001209 102.0
HKD1_k127_5041076_163 Cbs domain K04767 - - 0.00000000000000000000018 104.0
HKD1_k127_5041076_164 PFAM CBS domain containing protein K04767 - - 0.0000000000000000000003117 101.0
HKD1_k127_5041076_165 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000002741 103.0
HKD1_k127_5041076_166 HAD-superfamily hydrolase, subfamily IA, variant 1 - - - 0.000000000000000000003628 102.0
HKD1_k127_5041076_167 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.000000000000000000006415 106.0
HKD1_k127_5041076_168 PFAM OsmC family protein K07397 - - 0.00000000000000000000772 98.0
HKD1_k127_5041076_169 - - - - 0.00000000000000000004184 96.0
HKD1_k127_5041076_17 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 1.579e-206 652.0
HKD1_k127_5041076_170 Universal stress protein - - - 0.00000000000000000005445 97.0
HKD1_k127_5041076_171 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000001388 97.0
HKD1_k127_5041076_172 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0000000000000000001469 102.0
HKD1_k127_5041076_173 Acetyltransferase (GNAT) domain - - - 0.0000000000000000008049 100.0
HKD1_k127_5041076_174 Universal stress protein - - - 0.000000000000000002045 95.0
HKD1_k127_5041076_175 Universal stress protein K06149 - - 0.000000000000000004941 94.0
HKD1_k127_5041076_176 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000005424 84.0
HKD1_k127_5041076_177 Universal stress protein family - - - 0.00000000000000004486 90.0
HKD1_k127_5041076_178 MFS_1 like family - - - 0.00000000000000005486 93.0
HKD1_k127_5041076_179 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000003303 92.0
HKD1_k127_5041076_18 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.179e-202 659.0
HKD1_k127_5041076_180 peptidyl-tyrosine sulfation - - - 0.000000000000001407 88.0
HKD1_k127_5041076_181 Universal stress protein - - - 0.000000000000001813 89.0
HKD1_k127_5041076_182 CBS domain K04767 - - 0.000000000000001932 89.0
HKD1_k127_5041076_183 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.000000000000002133 84.0
HKD1_k127_5041076_184 PFAM UspA domain protein - - - 0.000000000000003836 91.0
HKD1_k127_5041076_185 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000001059 88.0
HKD1_k127_5041076_186 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000001428 81.0
HKD1_k127_5041076_187 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000001624 85.0
HKD1_k127_5041076_188 phosphorelay signal transduction system - - - 0.000000000000104 76.0
HKD1_k127_5041076_189 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000001065 71.0
HKD1_k127_5041076_19 Belongs to the RtcB family K14415 - 6.5.1.3 4.013e-201 636.0
HKD1_k127_5041076_190 Belongs to the universal stress protein A family - - - 0.00000000001671 77.0
HKD1_k127_5041076_191 Sigma-54 factor interaction domain-containing protein K02481,K07712,K07713 - - 0.0000000003858 73.0
HKD1_k127_5041076_192 Pfam PAP2 superfamily - - - 0.000000001122 69.0
HKD1_k127_5041076_193 Phosphorylase superfamily K03527 - 1.17.7.4 0.000000008105 67.0
HKD1_k127_5041076_194 Periplasmic binding protein domain K01999 - - 0.00000003971 66.0
HKD1_k127_5041076_195 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000182 63.0
HKD1_k127_5041076_196 acyl carrier protein - - - 0.000001403 57.0
HKD1_k127_5041076_197 Bacterial lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.00001363 56.0
HKD1_k127_5041076_198 Cytochrome c K02305 - - 0.00002031 55.0
HKD1_k127_5041076_199 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00006063 54.0
HKD1_k127_5041076_2 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1135.0
HKD1_k127_5041076_20 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 597.0
HKD1_k127_5041076_21 PFAM D-galactarate dehydratase Altronate hydrolase K01685 - 4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 583.0
HKD1_k127_5041076_22 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 558.0
HKD1_k127_5041076_23 PFAM Sodium sulphate symporter K03319,K11106 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 539.0
HKD1_k127_5041076_24 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 518.0
HKD1_k127_5041076_25 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 538.0
HKD1_k127_5041076_26 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 521.0
HKD1_k127_5041076_27 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 513.0
HKD1_k127_5041076_28 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 508.0
HKD1_k127_5041076_29 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 514.0
HKD1_k127_5041076_3 COG0474 Cation transport ATPase K01531 - 3.6.3.2 7.389e-312 980.0
HKD1_k127_5041076_30 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 506.0
HKD1_k127_5041076_31 PFAM Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 499.0
HKD1_k127_5041076_32 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 477.0
HKD1_k127_5041076_33 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 492.0
HKD1_k127_5041076_34 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 468.0
HKD1_k127_5041076_35 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 469.0
HKD1_k127_5041076_36 Pyruvate kinase, alpha/beta domain K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 461.0
HKD1_k127_5041076_37 FAD dependent oxidoreductase K00109 - 1.1.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 447.0
HKD1_k127_5041076_38 MacB-like periplasmic core domain K02004,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 460.0
HKD1_k127_5041076_39 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 441.0
HKD1_k127_5041076_4 NADH:flavin oxidoreductase / NADH oxidase family K21833 - - 4.534e-297 944.0
HKD1_k127_5041076_40 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 443.0
HKD1_k127_5041076_41 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 437.0
HKD1_k127_5041076_42 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 473.0
HKD1_k127_5041076_43 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 436.0
HKD1_k127_5041076_44 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 415.0
HKD1_k127_5041076_45 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 440.0
HKD1_k127_5041076_46 Peptidase dimerisation domain K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 414.0
HKD1_k127_5041076_47 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 434.0
HKD1_k127_5041076_48 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 396.0
HKD1_k127_5041076_49 NmrA-like family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 392.0
HKD1_k127_5041076_5 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.522e-296 927.0
HKD1_k127_5041076_50 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 409.0
HKD1_k127_5041076_51 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 391.0
HKD1_k127_5041076_52 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 400.0
HKD1_k127_5041076_53 Transport permease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 404.0
HKD1_k127_5041076_54 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 402.0
HKD1_k127_5041076_55 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 374.0
HKD1_k127_5041076_56 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 361.0
HKD1_k127_5041076_57 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 358.0
HKD1_k127_5041076_58 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 376.0
HKD1_k127_5041076_59 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 356.0
HKD1_k127_5041076_6 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.997e-295 925.0
HKD1_k127_5041076_60 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 354.0
HKD1_k127_5041076_61 Alanine dehydrogenase/PNT, C-terminal domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 357.0
HKD1_k127_5041076_62 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 344.0
HKD1_k127_5041076_63 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 343.0
HKD1_k127_5041076_64 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 346.0
HKD1_k127_5041076_65 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 332.0
HKD1_k127_5041076_66 Rieske 2Fe-2S K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 337.0
HKD1_k127_5041076_67 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 344.0
HKD1_k127_5041076_68 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 345.0
HKD1_k127_5041076_69 Aminotransferase K03430 - 2.6.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 336.0
HKD1_k127_5041076_7 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.117e-245 769.0
HKD1_k127_5041076_70 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 343.0
HKD1_k127_5041076_71 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 315.0
HKD1_k127_5041076_72 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510,K12660 - 4.1.2.52,4.1.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 325.0
HKD1_k127_5041076_73 phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009937 324.0
HKD1_k127_5041076_74 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 321.0
HKD1_k127_5041076_75 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 305.0
HKD1_k127_5041076_76 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 310.0
HKD1_k127_5041076_77 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 314.0
HKD1_k127_5041076_78 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 293.0
HKD1_k127_5041076_79 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 310.0
HKD1_k127_5041076_8 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 9.369e-241 775.0
HKD1_k127_5041076_80 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 291.0
HKD1_k127_5041076_81 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 288.0
HKD1_k127_5041076_82 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000205 286.0
HKD1_k127_5041076_83 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002237 282.0
HKD1_k127_5041076_84 Formate/nitrite transporter K06212 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009008 289.0
HKD1_k127_5041076_85 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002158 292.0
HKD1_k127_5041076_86 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000313 286.0
HKD1_k127_5041076_87 Peptidase family C69 K14358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004049 295.0
HKD1_k127_5041076_88 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003251 282.0
HKD1_k127_5041076_89 Universal stress protein UspA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002862 273.0
HKD1_k127_5041076_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 3.502e-239 777.0
HKD1_k127_5041076_90 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004183 291.0
HKD1_k127_5041076_91 Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP K00868 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008478,GO:0009058,GO:0009108,GO:0009110,GO:0009443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043094,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.7.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000044 275.0
HKD1_k127_5041076_92 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001109 273.0
HKD1_k127_5041076_93 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003079 269.0
HKD1_k127_5041076_94 ABC-type transport system involved in resistance to organic solvents permease component K02066 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001024 284.0
HKD1_k127_5041076_95 histidine kinase A domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008211 263.0
HKD1_k127_5041076_96 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000009582 252.0
HKD1_k127_5041076_97 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000004366 264.0
HKD1_k127_5041076_98 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007242 258.0
HKD1_k127_5041076_99 YHS domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008401 259.0
HKD1_k127_5045317_0 PFAM AMP-dependent synthetase and ligase K00666,K20034 - 6.2.1.44 9.004e-256 814.0
HKD1_k127_5045317_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 1.204e-205 655.0
HKD1_k127_5045317_10 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000005994 177.0
HKD1_k127_5045317_11 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.0000000000000000000000000000000000000009563 156.0
HKD1_k127_5045317_12 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000001507 157.0
HKD1_k127_5045317_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000001005 151.0
HKD1_k127_5045317_14 protein secretion K02460 - - 0.00000000000000000000000000000000004259 154.0
HKD1_k127_5045317_15 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K13039 - 4.1.1.79 0.0000000000000000000000000000000003237 138.0
HKD1_k127_5045317_16 sulfopyruvate decarboxylase, alpha subunit K06034 - 4.1.1.79 0.0000000000000000000000000001205 122.0
HKD1_k127_5045317_17 Thioredoxin - - - 0.000000000000000000000000002502 123.0
HKD1_k127_5045317_18 Pilus assembly protein K02461,K02662,K02663,K12289 - - 0.00000000000000000000042 113.0
HKD1_k127_5045317_19 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit S4 paralog K04762 - - 0.000000000000000000001548 110.0
HKD1_k127_5045317_2 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) - - - 2.64e-199 633.0
HKD1_k127_5045317_21 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.000000009689 68.0
HKD1_k127_5045317_23 Prokaryotic N-terminal methylation motif K02458 - - 0.00008646 55.0
HKD1_k127_5045317_24 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0008571 51.0
HKD1_k127_5045317_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 3.036e-194 616.0
HKD1_k127_5045317_4 major facilitator superfamily K02445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 374.0
HKD1_k127_5045317_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 345.0
HKD1_k127_5045317_6 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 339.0
HKD1_k127_5045317_7 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006767 285.0
HKD1_k127_5045317_9 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000006155 192.0
HKD1_k127_5069098_0 PFAM Glycosyl transferase family 2 - - - 0.0 1080.0
HKD1_k127_5069098_1 Uncharacterised protein family (UPF0182) K09118 - - 1.487e-280 889.0
HKD1_k127_5069098_10 - - - - 0.000000000000000000000000007614 121.0
HKD1_k127_5069098_11 Cupin - - - 0.0000000000002736 74.0
HKD1_k127_5069098_2 Fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 439.0
HKD1_k127_5069098_3 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 418.0
HKD1_k127_5069098_4 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 352.0
HKD1_k127_5069098_5 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 349.0
HKD1_k127_5069098_6 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005688 280.0
HKD1_k127_5069098_7 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000769 267.0
HKD1_k127_5069098_8 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000004863 193.0
HKD1_k127_5069098_9 - - - - 0.000000000000000000000000000000000000001085 159.0
HKD1_k127_5082561_0 Pyridoxal-dependent decarboxylase conserved domain - - - 5.375e-221 695.0
HKD1_k127_5082561_1 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 456.0
HKD1_k127_5082561_2 Phospholipase D Transphosphatidylase K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 394.0
HKD1_k127_5082561_3 Seven times multi-haem cytochrome CxxCH K10535 - 1.7.2.6 0.000000000000000000000000000000000000000000000000000003314 219.0
HKD1_k127_5082561_4 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000001494 184.0
HKD1_k127_5082561_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000005125 154.0
HKD1_k127_5082561_6 COG4520 Surface antigen - - - 0.000000000000000000000000000000006331 136.0
HKD1_k127_5082561_7 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000003284 131.0
HKD1_k127_5082561_8 carboxymuconolactone decarboxylase - - - 0.00000000004012 66.0
HKD1_k127_5082561_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000003424 68.0
HKD1_k127_5096200_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 8.108e-215 679.0
HKD1_k127_5096200_1 hydrolase, CocE NonD family K06978 - - 5.138e-195 625.0
HKD1_k127_5096200_10 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 338.0
HKD1_k127_5096200_11 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 318.0
HKD1_k127_5096200_12 Carbohydrate ABC transporter membrane protein 2, CUT1 family K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 307.0
HKD1_k127_5096200_13 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005579 295.0
HKD1_k127_5096200_14 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003793 276.0
HKD1_k127_5096200_15 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009193 276.0
HKD1_k127_5096200_16 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009316 296.0
HKD1_k127_5096200_17 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008781 282.0
HKD1_k127_5096200_18 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002586 278.0
HKD1_k127_5096200_19 mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000004918 230.0
HKD1_k127_5096200_2 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 443.0
HKD1_k127_5096200_20 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000004712 244.0
HKD1_k127_5096200_21 Acyl-CoA dehydrogenase type 2 K16047 GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006694,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009056,GO:0009058,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016712,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044238,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0044464,GO:0046164,GO:0048037,GO:0050660,GO:0050662,GO:0051704,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1902652 1.14.14.12 0.00000000000000000000000000000000000000000000000000000000006048 227.0
HKD1_k127_5096200_22 - - - - 0.000000000000000000000000000000000000000000000000000000001224 211.0
HKD1_k127_5096200_24 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000006023 211.0
HKD1_k127_5096200_25 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000006422 210.0
HKD1_k127_5096200_26 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.0000000000000000000000000000000000000000000000001738 183.0
HKD1_k127_5096200_27 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000633 183.0
HKD1_k127_5096200_28 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000147 179.0
HKD1_k127_5096200_29 PFAM Glycosyl transferase family 2 K12992 - - 0.00000000000000000000000000000000000004506 164.0
HKD1_k127_5096200_3 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 437.0
HKD1_k127_5096200_30 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000007232 162.0
HKD1_k127_5096200_32 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000003154 136.0
HKD1_k127_5096200_33 Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000002044 136.0
HKD1_k127_5096200_34 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000001174 132.0
HKD1_k127_5096200_35 Glycine-zipper domain - - - 0.0000000000000000000000001043 124.0
HKD1_k127_5096200_36 glycosyl transferase family 2 - - - 0.000000000000000000005087 106.0
HKD1_k127_5096200_37 - - - - 0.00000000000000001879 85.0
HKD1_k127_5096200_38 Luciferase-like monooxygenase - - - 0.0000000000000002156 85.0
HKD1_k127_5096200_39 OsmC-like protein - - - 0.0000000004822 69.0
HKD1_k127_5096200_4 COG1062 Zn-dependent alcohol dehydrogenases, class III K00001,K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 432.0
HKD1_k127_5096200_40 Mandelate Racemase Muconate Lactonizing K01781,K20023,K20549 - 4.2.1.156,4.2.1.42,5.1.2.2,5.5.1.25 0.000000007382 70.0
HKD1_k127_5096200_41 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00001508 53.0
HKD1_k127_5096200_5 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 439.0
HKD1_k127_5096200_6 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 387.0
HKD1_k127_5096200_7 PhoD-like phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 386.0
HKD1_k127_5096200_8 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 368.0
HKD1_k127_5096200_9 Luciferase-like monooxygenase K21731 - 1.14.13.162 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 349.0
HKD1_k127_5199374_0 lipopolysaccharide transport K22110 - - 0.0 1319.0
HKD1_k127_5199374_1 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 2.567e-299 974.0
HKD1_k127_5199374_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 579.0
HKD1_k127_5199374_11 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 497.0
HKD1_k127_5199374_12 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 492.0
HKD1_k127_5199374_13 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 459.0
HKD1_k127_5199374_14 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 446.0
HKD1_k127_5199374_15 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 427.0
HKD1_k127_5199374_16 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 417.0
HKD1_k127_5199374_17 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006633 389.0
HKD1_k127_5199374_18 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008593 394.0
HKD1_k127_5199374_19 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 382.0
HKD1_k127_5199374_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 7.052e-289 897.0
HKD1_k127_5199374_20 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 402.0
HKD1_k127_5199374_21 PFAM Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 352.0
HKD1_k127_5199374_22 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 351.0
HKD1_k127_5199374_23 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 347.0
HKD1_k127_5199374_24 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 375.0
HKD1_k127_5199374_25 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 337.0
HKD1_k127_5199374_26 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 343.0
HKD1_k127_5199374_27 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 321.0
HKD1_k127_5199374_28 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 306.0
HKD1_k127_5199374_29 Tetratricopeptide repeat K11935 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 310.0
HKD1_k127_5199374_3 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 8.259e-265 837.0
HKD1_k127_5199374_30 PFAM peptidase S58 DmpA K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 291.0
HKD1_k127_5199374_31 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000427 283.0
HKD1_k127_5199374_32 domain protein K03810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001126 289.0
HKD1_k127_5199374_33 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001669 287.0
HKD1_k127_5199374_34 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001674 282.0
HKD1_k127_5199374_35 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001403 275.0
HKD1_k127_5199374_36 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001058 273.0
HKD1_k127_5199374_37 Peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000002664 273.0
HKD1_k127_5199374_38 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001114 269.0
HKD1_k127_5199374_39 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002884 267.0
HKD1_k127_5199374_4 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 1.591e-246 772.0
HKD1_k127_5199374_40 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 GO:0006810,GO:0008150,GO:0015716,GO:0051179,GO:0051234,GO:0071702 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000004489 249.0
HKD1_k127_5199374_41 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.00000000000000000000000000000000000000000000000000000000000000000007247 246.0
HKD1_k127_5199374_42 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000004941 231.0
HKD1_k127_5199374_43 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000131 224.0
HKD1_k127_5199374_44 ABC-type multidrug transport system ATPase K01990,K16907 - - 0.00000000000000000000000000000000000000000000000000000000000001368 238.0
HKD1_k127_5199374_45 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000007826 230.0
HKD1_k127_5199374_46 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000009792 222.0
HKD1_k127_5199374_47 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000001122 219.0
HKD1_k127_5199374_48 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000001983 213.0
HKD1_k127_5199374_49 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000003705 215.0
HKD1_k127_5199374_5 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 9.807e-207 660.0
HKD1_k127_5199374_50 Phosphonate ABC transporter K02044 - - 0.0000000000000000000000000000000000000000000000000000004291 205.0
HKD1_k127_5199374_51 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000001494 203.0
HKD1_k127_5199374_52 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.00000000000000000000000000000000000000000000000000001346 214.0
HKD1_k127_5199374_53 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000002015 205.0
HKD1_k127_5199374_54 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000001799 201.0
HKD1_k127_5199374_55 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000002438 195.0
HKD1_k127_5199374_56 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000154 192.0
HKD1_k127_5199374_57 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon K03709 - - 0.00000000000000000000000000000000000000000000001337 181.0
HKD1_k127_5199374_58 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000001231 174.0
HKD1_k127_5199374_59 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000003082 153.0
HKD1_k127_5199374_6 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 587.0
HKD1_k127_5199374_60 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000003157 148.0
HKD1_k127_5199374_61 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000004872 143.0
HKD1_k127_5199374_62 recA bacterial DNA recombination protein - - - 0.000000000000000000000000000000004258 138.0
HKD1_k127_5199374_63 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000005685 135.0
HKD1_k127_5199374_64 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000005799 131.0
HKD1_k127_5199374_65 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000007073 145.0
HKD1_k127_5199374_66 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000000000862 145.0
HKD1_k127_5199374_67 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.000000000000000000000000000004597 128.0
HKD1_k127_5199374_68 Belongs to the ompA family K03640 - - 0.0000000000000000000000000004183 126.0
HKD1_k127_5199374_69 binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000001199 119.0
HKD1_k127_5199374_7 ABC transporter transmembrane region K02021 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 594.0
HKD1_k127_5199374_70 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000001958 116.0
HKD1_k127_5199374_71 S-adenosyl-L-methionine methyltransferase - - - 0.000000000000000000004673 102.0
HKD1_k127_5199374_72 Methionine biosynthesis protein MetW - - - 0.0000000000000000001023 104.0
HKD1_k127_5199374_73 Putative ATP-binding cassette K01992 - - 0.000000000000000002089 101.0
HKD1_k127_5199374_75 Peptidase family M28 - - - 0.0000000000009261 82.0
HKD1_k127_5199374_76 - - - - 0.000000000001563 74.0
HKD1_k127_5199374_77 protein secretion K03116 - - 0.0000000000135 72.0
HKD1_k127_5199374_78 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000002308 76.0
HKD1_k127_5199374_79 NMT1-like family K02051 GO:0003674,GO:0005215 - 0.0000000008359 71.0
HKD1_k127_5199374_8 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 550.0
HKD1_k127_5199374_80 PFAM ROSMUCR transcriptional regulator - - - 0.0000003519 58.0
HKD1_k127_5199374_81 VanZ like family - - - 0.000001155 57.0
HKD1_k127_5199374_82 YacP-like NYN domain K06962 - - 0.00004554 52.0
HKD1_k127_5199374_9 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 575.0
HKD1_k127_5206706_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1015.0
HKD1_k127_5206706_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 561.0
HKD1_k127_5206706_10 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 345.0
HKD1_k127_5206706_11 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 335.0
HKD1_k127_5206706_12 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 332.0
HKD1_k127_5206706_13 RmlD substrate binding domain K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 326.0
HKD1_k127_5206706_14 inositol 2-dehydrogenase activity K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 316.0
HKD1_k127_5206706_15 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 304.0
HKD1_k127_5206706_16 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 312.0
HKD1_k127_5206706_17 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 299.0
HKD1_k127_5206706_18 Bifunctional protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001385 283.0
HKD1_k127_5206706_19 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001594 250.0
HKD1_k127_5206706_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 538.0
HKD1_k127_5206706_20 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000001516 253.0
HKD1_k127_5206706_21 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000008966 245.0
HKD1_k127_5206706_22 Cytidylyltransferase K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000001022 241.0
HKD1_k127_5206706_23 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000004918 230.0
HKD1_k127_5206706_24 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000004651 228.0
HKD1_k127_5206706_25 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000002118 227.0
HKD1_k127_5206706_26 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02527,K02841,K02843,K12982 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000008533 211.0
HKD1_k127_5206706_27 PFAM Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.000000000000000000000000000000000000000000000000001326 205.0
HKD1_k127_5206706_28 transferase activity, transferring glycosyl groups K00754 - - 0.000000000000000000000000000000000000000000000000002983 205.0
HKD1_k127_5206706_29 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000002255 203.0
HKD1_k127_5206706_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 503.0
HKD1_k127_5206706_30 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000006803 186.0
HKD1_k127_5206706_31 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000007654 171.0
HKD1_k127_5206706_32 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000006147 170.0
HKD1_k127_5206706_33 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000007028 165.0
HKD1_k127_5206706_34 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000009352 168.0
HKD1_k127_5206706_35 Psort location Cytoplasmic, score 8.96 K09949 - - 0.00000000000000000000000000000000000000001357 164.0
HKD1_k127_5206706_36 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000003503 158.0
HKD1_k127_5206706_37 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000009727 153.0
HKD1_k127_5206706_38 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000002128 153.0
HKD1_k127_5206706_39 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000005153 138.0
HKD1_k127_5206706_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 459.0
HKD1_k127_5206706_40 Helix-turn-helix domain - - - 0.00000000000000008596 91.0
HKD1_k127_5206706_41 PFAM Outer membrane K06142 - - 0.0000000000000001967 94.0
HKD1_k127_5206706_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 417.0
HKD1_k127_5206706_6 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 389.0
HKD1_k127_5206706_7 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 366.0
HKD1_k127_5206706_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 347.0
HKD1_k127_5206706_9 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 355.0
HKD1_k127_5213832_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 331.0
HKD1_k127_5213832_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002688 284.0
HKD1_k127_5213832_2 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000416 275.0
HKD1_k127_5213832_3 pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000766 263.0
HKD1_k127_5213832_4 Pilus assembly protein K02664 - - 0.00000000000006296 79.0
HKD1_k127_5213832_5 Pilus assembly protein, PilP K02665 - - 0.000006854 57.0
HKD1_k127_5248475_0 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 452.0
HKD1_k127_5248475_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 346.0
HKD1_k127_5248475_2 Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 320.0
HKD1_k127_5248475_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000001791 231.0
HKD1_k127_5248475_4 Sulfatase - - - 0.00000000000000000000000000000000000001144 164.0
HKD1_k127_5248475_5 Methyltransferase domain - - - 0.000000000000000000000000000000000003929 149.0
HKD1_k127_5248475_6 Glycosyl transferase 4-like K19002 - 2.4.1.337 0.00000000000000000000002005 116.0
HKD1_k127_5248475_7 Cupin 2, conserved barrel domain protein - - - 0.00000001137 68.0
HKD1_k127_5248475_8 Glycosyl transferase, family 2 - - - 0.000001733 59.0
HKD1_k127_5273172_0 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 9.8e-322 1003.0
HKD1_k127_5273172_1 PFAM FAD linked oxidase domain protein - - - 3.296e-317 998.0
HKD1_k127_5273172_10 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 587.0
HKD1_k127_5273172_11 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 574.0
HKD1_k127_5273172_12 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 542.0
HKD1_k127_5273172_13 phosphorelay signal transduction system K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 496.0
HKD1_k127_5273172_14 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 493.0
HKD1_k127_5273172_15 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 456.0
HKD1_k127_5273172_16 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 453.0
HKD1_k127_5273172_17 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 432.0
HKD1_k127_5273172_18 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 434.0
HKD1_k127_5273172_19 Amidohydrolase family K15358 - 3.5.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 448.0
HKD1_k127_5273172_2 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 4.612e-260 811.0
HKD1_k127_5273172_20 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 412.0
HKD1_k127_5273172_21 TIGRFAM gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 440.0
HKD1_k127_5273172_22 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 396.0
HKD1_k127_5273172_23 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 408.0
HKD1_k127_5273172_24 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 408.0
HKD1_k127_5273172_25 PrpF protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 401.0
HKD1_k127_5273172_26 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 374.0
HKD1_k127_5273172_27 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 359.0
HKD1_k127_5273172_28 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 345.0
HKD1_k127_5273172_29 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 336.0
HKD1_k127_5273172_3 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 6.057e-253 800.0
HKD1_k127_5273172_30 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 337.0
HKD1_k127_5273172_31 Aminotransferase class-V K00830,K00839 - 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 349.0
HKD1_k127_5273172_32 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 329.0
HKD1_k127_5273172_33 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 323.0
HKD1_k127_5273172_34 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 301.0
HKD1_k127_5273172_35 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 304.0
HKD1_k127_5273172_36 TIGRFAM LPPG domain K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 300.0
HKD1_k127_5273172_37 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000667 288.0
HKD1_k127_5273172_38 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003257 302.0
HKD1_k127_5273172_39 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006028 288.0
HKD1_k127_5273172_4 MacB-like periplasmic core domain K02004 - - 1.172e-246 790.0
HKD1_k127_5273172_40 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005763 289.0
HKD1_k127_5273172_41 P-loop containing region of AAA domain K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005073 274.0
HKD1_k127_5273172_42 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000002965 277.0
HKD1_k127_5273172_43 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001255 278.0
HKD1_k127_5273172_44 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004983 269.0
HKD1_k127_5273172_45 Amino acid synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005108 266.0
HKD1_k127_5273172_46 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009238 254.0
HKD1_k127_5273172_47 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000006092 262.0
HKD1_k127_5273172_48 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000004693 236.0
HKD1_k127_5273172_49 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000008709 229.0
HKD1_k127_5273172_5 PFAM aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - - 1.346e-234 760.0
HKD1_k127_5273172_50 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000001885 228.0
HKD1_k127_5273172_51 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000003014 239.0
HKD1_k127_5273172_52 Belongs to the short-chain dehydrogenases reductases (SDR) family K03366 - 1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000001494 207.0
HKD1_k127_5273172_53 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000000000000000001766 221.0
HKD1_k127_5273172_54 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000001038 211.0
HKD1_k127_5273172_55 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000005031 194.0
HKD1_k127_5273172_56 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000002081 204.0
HKD1_k127_5273172_57 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000001487 192.0
HKD1_k127_5273172_58 - - - - 0.00000000000000000000000000000000000000000000000002615 188.0
HKD1_k127_5273172_59 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000135 188.0
HKD1_k127_5273172_6 helicase superfamily c-terminal domain K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 5.481e-225 730.0
HKD1_k127_5273172_60 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000002966 162.0
HKD1_k127_5273172_61 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000008476 168.0
HKD1_k127_5273172_62 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.000000000000000000000000000000000000000005241 178.0
HKD1_k127_5273172_63 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000733 161.0
HKD1_k127_5273172_64 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs - - - 0.00000000000000000000000000000000000001694 158.0
HKD1_k127_5273172_65 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000001232 156.0
HKD1_k127_5273172_66 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000001195 149.0
HKD1_k127_5273172_67 Flavin reductase like domain - - - 0.000000000000000000000000000000000001453 160.0
HKD1_k127_5273172_68 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000001416 138.0
HKD1_k127_5273172_69 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000002951 136.0
HKD1_k127_5273172_7 Aconitase C-terminal domain K01681 - 4.2.1.3 1.187e-222 708.0
HKD1_k127_5273172_70 Lipid A Biosynthesis - - - 0.0000000000000000000000000000009768 128.0
HKD1_k127_5273172_71 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.000000000000000000000000000003779 138.0
HKD1_k127_5273172_72 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000005942 132.0
HKD1_k127_5273172_73 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000006123 119.0
HKD1_k127_5273172_74 regulation of translation K03530 - - 0.00000000000000000000003245 115.0
HKD1_k127_5273172_75 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000007031 114.0
HKD1_k127_5273172_76 SMART protein phosphatase 2C domain protein - - - 0.00000000000000000001896 99.0
HKD1_k127_5273172_77 Belongs to the ompA family - - - 0.00000000000000000004703 103.0
HKD1_k127_5273172_78 COG2146 Ferredoxin subunits of nitrite reductase and K00363 - 1.7.1.15 0.00000000000000000007224 93.0
HKD1_k127_5273172_79 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000001071 88.0
HKD1_k127_5273172_8 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.769e-214 676.0
HKD1_k127_5273172_80 Trypsin K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000001062 89.0
HKD1_k127_5273172_81 Membrane - - - 0.00000000000416 78.0
HKD1_k127_5273172_82 Lrp/AsnC ligand binding domain - - - 0.00000000001793 67.0
HKD1_k127_5273172_83 Sulfurtransferase TusA K04085 - - 0.0000000000214 76.0
HKD1_k127_5273172_84 - - - - 0.0000000674 61.0
HKD1_k127_5273172_85 HD domain K07814 - - 0.0000002772 62.0
HKD1_k127_5273172_86 integral membrane protein - - - 0.0000007332 61.0
HKD1_k127_5273172_87 Belongs to the peptidase S1C family - - - 0.0000148 58.0
HKD1_k127_5273172_89 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0005632 52.0
HKD1_k127_5273172_9 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.372e-201 644.0
HKD1_k127_5322615_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1109.0
HKD1_k127_5322615_1 TrkA-N domain K03455,K10716 - - 1.269e-198 634.0
HKD1_k127_5322615_10 III protein, CoA-transferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 406.0
HKD1_k127_5322615_11 Extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 423.0
HKD1_k127_5322615_12 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 385.0
HKD1_k127_5322615_13 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 387.0
HKD1_k127_5322615_14 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 365.0
HKD1_k127_5322615_15 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 366.0
HKD1_k127_5322615_16 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 323.0
HKD1_k127_5322615_17 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 316.0
HKD1_k127_5322615_18 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 300.0
HKD1_k127_5322615_19 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 300.0
HKD1_k127_5322615_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 588.0
HKD1_k127_5322615_20 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001178 273.0
HKD1_k127_5322615_21 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.000000000000000000000000000000000000000000000000000000000000000000000000004119 290.0
HKD1_k127_5322615_22 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003225 256.0
HKD1_k127_5322615_23 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000468 246.0
HKD1_k127_5322615_24 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000002876 252.0
HKD1_k127_5322615_25 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002288 245.0
HKD1_k127_5322615_26 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000001387 230.0
HKD1_k127_5322615_27 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000002627 235.0
HKD1_k127_5322615_28 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001507 233.0
HKD1_k127_5322615_29 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000003717 223.0
HKD1_k127_5322615_3 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 518.0
HKD1_k127_5322615_30 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000001865 221.0
HKD1_k127_5322615_31 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000004755 194.0
HKD1_k127_5322615_32 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000001714 191.0
HKD1_k127_5322615_33 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000488 206.0
HKD1_k127_5322615_34 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000000000000000000000000000000000000003799 196.0
HKD1_k127_5322615_35 KR domain - - - 0.000000000000000000000000000000000000000000005789 179.0
HKD1_k127_5322615_36 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000003425 161.0
HKD1_k127_5322615_37 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000004841 166.0
HKD1_k127_5322615_38 lactate metabolic process - - - 0.000000000000000000000000000000000000002814 166.0
HKD1_k127_5322615_39 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000004119 146.0
HKD1_k127_5322615_4 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 477.0
HKD1_k127_5322615_40 OmpA family K03640 - - 0.00000000000000000000000000000000008997 138.0
HKD1_k127_5322615_41 PFAM AzlC family protein - - - 0.0000000000000000000000000000000003349 143.0
HKD1_k127_5322615_42 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000001024 134.0
HKD1_k127_5322615_43 EamA-like transporter family - - - 0.00000000000000000000000000002126 132.0
HKD1_k127_5322615_44 Ferric uptake regulator family K09825 - - 0.0000000000000000000000000002472 134.0
HKD1_k127_5322615_45 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000001794 125.0
HKD1_k127_5322615_46 Hep Hag repeat protein - - - 0.000000000000000000000000005383 120.0
HKD1_k127_5322615_47 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000002097 107.0
HKD1_k127_5322615_48 Cupin domain - - - 0.00000000000000000000003534 103.0
HKD1_k127_5322615_49 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000000002882 99.0
HKD1_k127_5322615_5 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 436.0
HKD1_k127_5322615_50 Transglutaminase-like superfamily - - - 0.00000000000000000003619 95.0
HKD1_k127_5322615_51 Gram-negative-bacterium-type cell outer membrane assembly - - - 0.0000000000000000004221 94.0
HKD1_k127_5322615_52 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.000000000001161 80.0
HKD1_k127_5322615_53 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.000000000006261 73.0
HKD1_k127_5322615_54 lipolytic protein G-D-S-L family - - - 0.0000000001262 74.0
HKD1_k127_5322615_56 Uncharacterized conserved protein (DUF2267) - - - 0.0000001431 60.0
HKD1_k127_5322615_57 Branched-chain amino acid transport protein (AzlD) - - - 0.0000276 56.0
HKD1_k127_5322615_58 transcriptional regulator - - - 0.0001427 51.0
HKD1_k127_5322615_59 Lipopolysaccharide assembly protein A domain K08992 - - 0.000224 48.0
HKD1_k127_5322615_6 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 440.0
HKD1_k127_5322615_60 Cystathionine beta-lyase K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0006301 51.0
HKD1_k127_5322615_7 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 426.0
HKD1_k127_5322615_8 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 427.0
HKD1_k127_5322615_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 413.0
HKD1_k127_5356501_0 Belongs to the GcvT family - - - 0.0 1170.0
HKD1_k127_5356501_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 505.0
HKD1_k127_5356501_10 Low molecular weight phosphatase family K03741 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 0.000000000000000000000000000000000000000000000000002108 186.0
HKD1_k127_5356501_11 pyridoxamine 5-phosphate - - - 0.000000000000000002469 100.0
HKD1_k127_5356501_12 Cupin - - - 0.0000007588 51.0
HKD1_k127_5356501_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 418.0
HKD1_k127_5356501_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 422.0
HKD1_k127_5356501_4 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 319.0
HKD1_k127_5356501_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001922 278.0
HKD1_k127_5356501_6 Electron transfer flavoprotein, beta subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007894 272.0
HKD1_k127_5356501_7 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001899 244.0
HKD1_k127_5356501_8 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000003941 243.0
HKD1_k127_5356501_9 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000000000000000000000000000000000000001601 187.0
HKD1_k127_5469435_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 4.508e-214 702.0
HKD1_k127_5469435_1 Transglycosylase K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 560.0
HKD1_k127_5469435_10 - - - - 0.0000000000000000000000000000000000003865 142.0
HKD1_k127_5469435_11 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.000000000000000000000000000000005262 137.0
HKD1_k127_5469435_12 - - - - 0.0000000000000000000000001664 107.0
HKD1_k127_5469435_13 - - - - 0.000000000000000000004894 94.0
HKD1_k127_5469435_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000001193 85.0
HKD1_k127_5469435_15 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K00887,K00901 - 2.7.1.107,2.7.1.66 0.00000000000000001288 96.0
HKD1_k127_5469435_16 Regulatory protein, FmdB family - - - 0.000000000000003003 87.0
HKD1_k127_5469435_17 - - - - 0.00000000001412 66.0
HKD1_k127_5469435_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 453.0
HKD1_k127_5469435_3 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 383.0
HKD1_k127_5469435_4 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 359.0
HKD1_k127_5469435_5 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009875 279.0
HKD1_k127_5469435_6 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000005813 252.0
HKD1_k127_5469435_7 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000004978 225.0
HKD1_k127_5469435_8 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000001271 177.0
HKD1_k127_5469435_9 COG NOG14552 non supervised orthologous group - - - 0.0000000000000000000000000000000000000372 146.0
HKD1_k127_5568005_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 382.0
HKD1_k127_5568005_1 ABC transporter, ATP-binding protein K02028,K02029 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 310.0
HKD1_k127_5568005_2 ABC transporter substrate-binding protein K02030 - - 0.00000000000000000000000000000000000000000000000000000000003045 225.0
HKD1_k127_5568005_3 PFAM Isochorismatase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000004394 206.0
HKD1_k127_5568005_4 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000001472 190.0
HKD1_k127_5568005_5 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000002984 173.0
HKD1_k127_5568005_6 acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine K02029 - - 0.00000000000000000000000000000000000000009904 158.0
HKD1_k127_563461_0 drug resistance transporter, EmrB QacA subfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 609.0
HKD1_k127_563461_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 610.0
HKD1_k127_563461_10 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008463 285.0
HKD1_k127_563461_11 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001018 280.0
HKD1_k127_563461_12 ABC transporter substrate-binding protein K11077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003286 269.0
HKD1_k127_563461_13 binding-protein-dependent transport systems inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005001 262.0
HKD1_k127_563461_14 COG2309 Leucyl aminopeptidase (aminopeptidase T) - - - 0.000000000000000000000000000000000000000000000000000000000000001653 231.0
HKD1_k127_563461_15 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000003113 226.0
HKD1_k127_563461_16 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000003806 220.0
HKD1_k127_563461_17 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000002915 215.0
HKD1_k127_563461_18 Short-chain dehydrogenase reductase sdr K07535 - - 0.000000000000000000000000000000000000000000000004359 181.0
HKD1_k127_563461_19 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000002498 173.0
HKD1_k127_563461_2 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 555.0
HKD1_k127_563461_20 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000004055 153.0
HKD1_k127_563461_21 Thioesterase superfamily - - - 0.00000000000000000000000000000000000006091 146.0
HKD1_k127_563461_22 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000005223 159.0
HKD1_k127_563461_23 NMT1-like family K02051 - - 0.00000000000000000000000000000000004479 154.0
HKD1_k127_563461_24 CTP synthase K01937 - 6.3.4.2 0.000000000000006484 77.0
HKD1_k127_563461_25 - - - - 0.0000000000125 68.0
HKD1_k127_563461_26 - - - - 0.000000005445 68.0
HKD1_k127_563461_27 Cupin 2, conserved barrel domain protein - - - 0.00007461 51.0
HKD1_k127_563461_28 - - - - 0.0005787 52.0
HKD1_k127_563461_3 cell redox homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 335.0
HKD1_k127_563461_4 Acetolactate synthase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 343.0
HKD1_k127_563461_5 import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 334.0
HKD1_k127_563461_6 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 310.0
HKD1_k127_563461_7 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 293.0
HKD1_k127_563461_8 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049,K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009449 295.0
HKD1_k127_563461_9 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001774 286.0
HKD1_k127_5698339_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 595.0
HKD1_k127_5698339_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 344.0
HKD1_k127_5698339_2 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001776 251.0
HKD1_k127_5698339_3 Oxidoreductase family, NAD-binding Rossmann fold K13327 - 1.1.1.384 0.0000000000000000000003367 106.0
HKD1_k127_5698339_4 MFS_1 like family - - - 0.000000001506 70.0
HKD1_k127_5704544_0 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 488.0
HKD1_k127_5704544_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 410.0
HKD1_k127_5704544_2 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 411.0
HKD1_k127_5704544_3 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 357.0
HKD1_k127_5704544_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000001176 132.0
HKD1_k127_5719789_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 477.0
HKD1_k127_5719789_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 426.0
HKD1_k127_5719789_10 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000006105 114.0
HKD1_k127_5719789_11 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000001099 107.0
HKD1_k127_5719789_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 441.0
HKD1_k127_5719789_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 339.0
HKD1_k127_5719789_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000006647 252.0
HKD1_k127_5719789_5 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000005447 243.0
HKD1_k127_5719789_6 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000489 244.0
HKD1_k127_5719789_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000006311 215.0
HKD1_k127_5719789_8 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000002008 206.0
HKD1_k127_5719789_9 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000001668 190.0
HKD1_k127_5750256_0 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 1.754e-228 734.0
HKD1_k127_5750256_1 PFAM Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.534e-212 701.0
HKD1_k127_5750256_2 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 455.0
HKD1_k127_5750256_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 293.0
HKD1_k127_5750256_4 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000006962 204.0
HKD1_k127_5750256_5 phosphatidylinositol metabolic process - - - 0.000000000000000000000000000000000000000000000000000003339 204.0
HKD1_k127_5750256_6 Evidence 5 No homology to any previously reported sequences K03765 - - 0.0000000000000000000000000000194 135.0
HKD1_k127_5750256_7 YtxH-like protein - - - 0.0000001598 59.0
HKD1_k127_586029_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1329.0
HKD1_k127_586029_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1255.0
HKD1_k127_586029_10 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 1.221e-214 677.0
HKD1_k127_586029_100 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000001429 141.0
HKD1_k127_586029_101 manganese ion transmembrane transporter activity - - - 0.0000000000000000000000000000001633 144.0
HKD1_k127_586029_102 PFAM SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.000000000000000000000000000006725 127.0
HKD1_k127_586029_103 In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.00000000000000000000000004275 110.0
HKD1_k127_586029_104 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000245 119.0
HKD1_k127_586029_105 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000009613 117.0
HKD1_k127_586029_106 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000309 116.0
HKD1_k127_586029_107 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10672 - 1.21.4.2 0.000000000000000000001015 96.0
HKD1_k127_586029_108 cheY-homologous receiver domain K11443 - - 0.00000000000000001239 88.0
HKD1_k127_586029_109 Xylose isomerase-like TIM barrel - - - 0.0000000000000001327 89.0
HKD1_k127_586029_11 CHAP domain - - - 1.234e-207 662.0
HKD1_k127_586029_110 Biotin-requiring enzyme - - - 0.000000000000002133 84.0
HKD1_k127_586029_111 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000001464 77.0
HKD1_k127_586029_112 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000003703 82.0
HKD1_k127_586029_113 Thioredoxin-like - - - 0.000000000003674 70.0
HKD1_k127_586029_114 Glycine sarcosine betaine reductase complex K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0000000004652 61.0
HKD1_k127_586029_115 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K10118 - - 0.0000002512 58.0
HKD1_k127_586029_116 Inositol monophosphatase K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.000003481 60.0
HKD1_k127_586029_118 Thioredoxin-like - - - 0.000009855 57.0
HKD1_k127_586029_119 hyalurononglucosaminidase activity K22144 GO:0001947,GO:0002009,GO:0003007,GO:0003143,GO:0003170,GO:0003171,GO:0003179,GO:0003181,GO:0003188,GO:0003190,GO:0003197,GO:0003318,GO:0003674,GO:0003824,GO:0004415,GO:0004553,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006807,GO:0006928,GO:0007275,GO:0007368,GO:0007389,GO:0007507,GO:0007517,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009653,GO:0009790,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009966,GO:0009967,GO:0009987,GO:0010646,GO:0010647,GO:0014706,GO:0015929,GO:0016020,GO:0016021,GO:0016054,GO:0016203,GO:0016477,GO:0016787,GO:0016798,GO:0019752,GO:0022603,GO:0023051,GO:0023056,GO:0030203,GO:0030212,GO:0030214,GO:0031224,GO:0031226,GO:0032501,GO:0032502,GO:0035050,GO:0035239,GO:0035295,GO:0040011,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044087,GO:0044089,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0045765,GO:0046395,GO:0046872,GO:0048513,GO:0048518,GO:0048522,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048644,GO:0048645,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048856,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051130,GO:0051179,GO:0051239,GO:0051674,GO:0055008,GO:0060415,GO:0060429,GO:0060485,GO:0060537,GO:0060538,GO:0060562,GO:0060914,GO:0060973,GO:0060974,GO:0061061,GO:0061371,GO:0065007,GO:0071704,GO:0071944,GO:0072359,GO:0090287,GO:1900746,GO:1900748,GO:1901135,GO:1901136,GO:1901201,GO:1901203,GO:1901342,GO:1901564,GO:1901565,GO:1901575,GO:1902547,GO:1903053,GO:1903055,GO:1903510,GO:1903670,GO:2000026 3.2.1.35 0.00003374 57.0
HKD1_k127_586029_12 dehydrogenase - - - 6.009e-205 658.0
HKD1_k127_586029_120 PFAM AhpC TSA family - - - 0.0001312 47.0
HKD1_k127_586029_121 - - - - 0.0001952 50.0
HKD1_k127_586029_122 Permease for cytosine/purines, uracil, thiamine, allantoin - - - 0.0003464 51.0
HKD1_k127_586029_123 PFAM thiamineS protein K03636 - - 0.0005817 44.0
HKD1_k127_586029_13 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 601.0
HKD1_k127_586029_14 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 563.0
HKD1_k127_586029_15 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 549.0
HKD1_k127_586029_16 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 548.0
HKD1_k127_586029_17 ABC-type Fe3 transport system, periplasmic component K02012,K11081 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 542.0
HKD1_k127_586029_18 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 542.0
HKD1_k127_586029_19 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 497.0
HKD1_k127_586029_2 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1092.0
HKD1_k127_586029_20 pyridine K00322 - 1.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 502.0
HKD1_k127_586029_21 PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 532.0
HKD1_k127_586029_22 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 509.0
HKD1_k127_586029_23 Oligopeptide/dipeptide transporter, C-terminal region K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 480.0
HKD1_k127_586029_24 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 483.0
HKD1_k127_586029_25 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 471.0
HKD1_k127_586029_26 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 476.0
HKD1_k127_586029_27 Oligopeptide/dipeptide transporter, C-terminal region K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 445.0
HKD1_k127_586029_28 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 436.0
HKD1_k127_586029_29 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 434.0
HKD1_k127_586029_3 ABC-type Fe3 transport system permease component K02011 - - 1.209e-301 942.0
HKD1_k127_586029_30 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 456.0
HKD1_k127_586029_31 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 422.0
HKD1_k127_586029_32 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 421.0
HKD1_k127_586029_33 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 411.0
HKD1_k127_586029_34 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 406.0
HKD1_k127_586029_35 phosphate ion binding K02040 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010921,GO:0015698,GO:0019220,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031975,GO:0033554,GO:0035303,GO:0042301,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0065007,GO:0065009 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 405.0
HKD1_k127_586029_36 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 400.0
HKD1_k127_586029_37 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 395.0
HKD1_k127_586029_38 PFAM luciferase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 381.0
HKD1_k127_586029_39 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 394.0
HKD1_k127_586029_4 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239,K00278 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4,1.4.3.16 2.876e-290 915.0
HKD1_k127_586029_40 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 375.0
HKD1_k127_586029_41 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 371.0
HKD1_k127_586029_42 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 379.0
HKD1_k127_586029_43 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 361.0
HKD1_k127_586029_44 Gamma-glutamyltranspeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 376.0
HKD1_k127_586029_45 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 375.0
HKD1_k127_586029_46 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 372.0
HKD1_k127_586029_47 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 355.0
HKD1_k127_586029_48 TOBE domain K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 366.0
HKD1_k127_586029_49 Gamma-glutamyltranspeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 350.0
HKD1_k127_586029_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.45e-266 833.0
HKD1_k127_586029_50 PFAM ABC transporter related K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 338.0
HKD1_k127_586029_51 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10672,K21584 - 1.21.4.2,1.21.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 329.0
HKD1_k127_586029_52 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 334.0
HKD1_k127_586029_53 mandelate racemase muconate lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 326.0
HKD1_k127_586029_54 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 326.0
HKD1_k127_586029_55 amp-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 341.0
HKD1_k127_586029_56 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 321.0
HKD1_k127_586029_57 Cys/Met metabolism PLP-dependent enzyme K19715 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 330.0
HKD1_k127_586029_58 Mandelate racemase muconate lactonizing enzyme K18983 - 5.5.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 306.0
HKD1_k127_586029_59 Glycosyltransferase like family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 319.0
HKD1_k127_586029_6 Belongs to the TPP enzyme family K03336 - 3.7.1.22 9.703e-254 797.0
HKD1_k127_586029_60 phosphosulfolactate synthase activity K08097 - 4.4.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 295.0
HKD1_k127_586029_61 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 298.0
HKD1_k127_586029_62 Phosphate transport system permease protein PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 315.0
HKD1_k127_586029_63 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006671 306.0
HKD1_k127_586029_64 Two component transcriptional regulator, winged helix family K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003179 278.0
HKD1_k127_586029_65 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001463 279.0
HKD1_k127_586029_66 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000157 278.0
HKD1_k127_586029_67 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000248 287.0
HKD1_k127_586029_68 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002719 301.0
HKD1_k127_586029_69 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000181 273.0
HKD1_k127_586029_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 8.379e-249 782.0
HKD1_k127_586029_70 transposition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007757 276.0
HKD1_k127_586029_71 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008925 268.0
HKD1_k127_586029_72 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001304 272.0
HKD1_k127_586029_73 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000127 254.0
HKD1_k127_586029_74 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009377 257.0
HKD1_k127_586029_75 phosphinothricin N-acetyltransferase activity K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000000001174 239.0
HKD1_k127_586029_76 spermidine putrescine K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000003887 243.0
HKD1_k127_586029_77 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000004629 242.0
HKD1_k127_586029_78 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000001647 227.0
HKD1_k127_586029_79 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000005618 228.0
HKD1_k127_586029_8 elongation factor Tu domain 2 protein K02355 - - 1.786e-230 733.0
HKD1_k127_586029_80 helix_turn _helix lactose operon repressor K05499 - - 0.00000000000000000000000000000000000000000000000000000005452 210.0
HKD1_k127_586029_81 ABC transporter permease - - - 0.0000000000000000000000000000000000000000000000000000005761 214.0
HKD1_k127_586029_82 Oxidoreductase family, NAD-binding Rossmann fold K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000085 206.0
HKD1_k127_586029_83 Glycine sarcosine betaine reductase K10671 - 1.21.4.2 0.00000000000000000000000000000000000000000000000000001132 215.0
HKD1_k127_586029_84 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000002044 194.0
HKD1_k127_586029_85 Xylose isomerase domain protein TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.0000000000000000000000000000000000000000000000000000343 211.0
HKD1_k127_586029_86 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000003668 216.0
HKD1_k127_586029_87 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000735 202.0
HKD1_k127_586029_88 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.0000000000000000000000000000000000000000000000001324 186.0
HKD1_k127_586029_89 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000001865 183.0
HKD1_k127_586029_9 Belongs to the ILVD EDD family - - - 5.554e-227 721.0
HKD1_k127_586029_90 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000007387 185.0
HKD1_k127_586029_91 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000001257 192.0
HKD1_k127_586029_92 LysE type translocator - - - 0.000000000000000000000000000000000000000000000001776 181.0
HKD1_k127_586029_93 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000001588 186.0
HKD1_k127_586029_94 Putrescine transport system permease K11075 - - 0.00000000000000000000000000000000000000000000001876 183.0
HKD1_k127_586029_95 PRMT5 arginine-N-methyltransferase K11434 - 2.1.1.319 0.0000000000000000000000000000000000000000001 175.0
HKD1_k127_586029_96 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000003801 171.0
HKD1_k127_586029_97 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000002175 152.0
HKD1_k127_586029_98 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000000002479 150.0
HKD1_k127_586029_99 Putative regulatory protein - - - 0.000000000000000000000000000000000007308 139.0
HKD1_k127_59132_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 9.315e-247 777.0
HKD1_k127_59132_1 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 474.0
HKD1_k127_59132_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 412.0
HKD1_k127_5928981_0 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 612.0
HKD1_k127_5928981_1 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 534.0
HKD1_k127_5928981_10 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000003264 177.0
HKD1_k127_5928981_11 Hydrolase - - - 0.0000000000000000000000000000000003945 140.0
HKD1_k127_5928981_12 - - - - 0.000000000000000000000000000000003227 147.0
HKD1_k127_5928981_13 rRNA (guanine-N2-)-methyltransferase activity - - - 0.000000000000000000000186 105.0
HKD1_k127_5928981_14 Protein of unknown function (DUF1318) K09978 - - 0.0000000000008185 77.0
HKD1_k127_5928981_15 sorbosone dehydrogenase - - - 0.00000000002812 64.0
HKD1_k127_5928981_16 pyridoxamine 5'-phosphate K07005,K07006 - - 0.00000008574 59.0
HKD1_k127_5928981_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 468.0
HKD1_k127_5928981_3 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 393.0
HKD1_k127_5928981_4 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 385.0
HKD1_k127_5928981_5 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 342.0
HKD1_k127_5928981_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003242 299.0
HKD1_k127_5928981_7 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002292 257.0
HKD1_k127_5928981_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000000000000000000000000000000002713 207.0
HKD1_k127_5928981_9 Inositol monophosphatase family K05602 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000001768 198.0
HKD1_k127_6039326_0 formate dehydrogenase (NAD+) activity K00123,K05299 - 1.17.1.10,1.17.1.9 1.764e-232 756.0
HKD1_k127_6039326_1 Ammonium Transporter Family K03320 - - 1.173e-202 646.0
HKD1_k127_6039326_10 SNF2 family N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 308.0
HKD1_k127_6039326_11 Glycine reductase complex component B subunit gamma K10672 - 1.21.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001957 304.0
HKD1_k127_6039326_12 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005054 286.0
HKD1_k127_6039326_13 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 280.0
HKD1_k127_6039326_14 Binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003421 288.0
HKD1_k127_6039326_15 alpha, beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004259 264.0
HKD1_k127_6039326_16 ABC-type amino acid transport system, permease component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001071 256.0
HKD1_k127_6039326_17 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000123 248.0
HKD1_k127_6039326_18 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000004131 241.0
HKD1_k127_6039326_19 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000009782 241.0
HKD1_k127_6039326_2 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 621.0
HKD1_k127_6039326_20 Wzt C-terminal domain K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000001974 230.0
HKD1_k127_6039326_21 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000005617 241.0
HKD1_k127_6039326_22 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000006906 221.0
HKD1_k127_6039326_23 Glycine sarcosine betaine reductase K10671 - 1.21.4.2 0.00000000000000000000000000000000000000000000000000004178 204.0
HKD1_k127_6039326_24 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000001761 199.0
HKD1_k127_6039326_25 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000001505 186.0
HKD1_k127_6039326_26 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000001601 193.0
HKD1_k127_6039326_27 o-methyltransferase - - - 0.00000000000000000000000000000000000000000000002892 176.0
HKD1_k127_6039326_28 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000005484 172.0
HKD1_k127_6039326_29 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000003966 183.0
HKD1_k127_6039326_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 537.0
HKD1_k127_6039326_30 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000008206 179.0
HKD1_k127_6039326_31 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000003904 173.0
HKD1_k127_6039326_32 COGs COG3372 conserved K09744 - - 0.0000000000000000000000000000000000000007052 164.0
HKD1_k127_6039326_33 Thioredoxin domain - - - 0.0000000000000000000000000000000001947 140.0
HKD1_k127_6039326_34 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 0.00000000000000000000000000000101 139.0
HKD1_k127_6039326_35 Transport permease protein K01992 - - 0.000000000000000000000000000007001 129.0
HKD1_k127_6039326_36 TIGRFAM Glutaredoxin-like domain protein - - - 0.00000000000000000001793 92.0
HKD1_k127_6039326_37 Selenoprotein B, glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.000000000000000001136 88.0
HKD1_k127_6039326_38 radical SAM domain protein - - - 0.00000000000000000531 100.0
HKD1_k127_6039326_39 PFAM AIG2-like - - - 0.00000000000000009703 86.0
HKD1_k127_6039326_4 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008642 494.0
HKD1_k127_6039326_40 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000768 55.0
HKD1_k127_6039326_5 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 360.0
HKD1_k127_6039326_6 (ABC) transporter K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 324.0
HKD1_k127_6039326_7 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 333.0
HKD1_k127_6039326_8 Aldolase/RraA K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 299.0
HKD1_k127_6039326_9 COGs COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 302.0
HKD1_k127_6075056_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1590.0
HKD1_k127_6075056_1 ATPase (P-type) K01535 - 3.6.3.6 6.514e-310 972.0
HKD1_k127_6075056_10 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 427.0
HKD1_k127_6075056_11 PFAM ATP-binding region ATPase domain protein K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 421.0
HKD1_k127_6075056_12 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 436.0
HKD1_k127_6075056_13 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 387.0
HKD1_k127_6075056_14 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 349.0
HKD1_k127_6075056_15 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 344.0
HKD1_k127_6075056_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 355.0
HKD1_k127_6075056_17 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 295.0
HKD1_k127_6075056_18 Poly A polymerase head domain K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001383 298.0
HKD1_k127_6075056_19 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005486 283.0
HKD1_k127_6075056_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 5.733e-302 939.0
HKD1_k127_6075056_20 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007284 281.0
HKD1_k127_6075056_21 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000003517 248.0
HKD1_k127_6075056_22 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000001631 234.0
HKD1_k127_6075056_23 Transcriptional regulatory protein, C terminal K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000006685 226.0
HKD1_k127_6075056_24 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000004678 221.0
HKD1_k127_6075056_25 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000009841 229.0
HKD1_k127_6075056_26 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000005235 229.0
HKD1_k127_6075056_27 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000006347 215.0
HKD1_k127_6075056_28 PEP-CTERM motif - - - 0.0000000000000000000000000000000000000000000000000000000007113 224.0
HKD1_k127_6075056_29 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000000000000000000000000000000000000000000000001095 212.0
HKD1_k127_6075056_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K03737 - 1.2.7.1 1.534e-256 808.0
HKD1_k127_6075056_30 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000000000000000001841 217.0
HKD1_k127_6075056_31 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000102 204.0
HKD1_k127_6075056_32 coenzyme F390 K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000994 203.0
HKD1_k127_6075056_33 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000000000000000000000000000000003351 192.0
HKD1_k127_6075056_34 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000597 203.0
HKD1_k127_6075056_35 - K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000000000007027 181.0
HKD1_k127_6075056_36 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000003074 180.0
HKD1_k127_6075056_37 M6 family metalloprotease domain protein - - - 0.000000000000000000000000000000000000000000000108 194.0
HKD1_k127_6075056_38 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000009789 186.0
HKD1_k127_6075056_39 - - - - 0.000000000000000000000000000000000000000000008877 179.0
HKD1_k127_6075056_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 5.607e-234 749.0
HKD1_k127_6075056_40 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000004351 179.0
HKD1_k127_6075056_41 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000927 181.0
HKD1_k127_6075056_42 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000004956 163.0
HKD1_k127_6075056_43 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000000002012 148.0
HKD1_k127_6075056_44 PFAM Di-haem cytochrome c - - - 0.000000000000000000000000000000000000104 147.0
HKD1_k127_6075056_45 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000006806 153.0
HKD1_k127_6075056_46 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000002762 139.0
HKD1_k127_6075056_47 outer membrane autotransporter barrel domain - - - 0.000000000000000000000000000000002469 148.0
HKD1_k127_6075056_48 pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.000000000000000000000000000000009036 143.0
HKD1_k127_6075056_49 Required for disulfide bond formation in some proteins K03611 - - 0.0000000000000000000000000000003005 129.0
HKD1_k127_6075056_5 Adenylate and Guanylate cyclase catalytic domain - - - 2.417e-207 654.0
HKD1_k127_6075056_50 CBS domain - - - 0.0000000000000000000000000000006143 128.0
HKD1_k127_6075056_51 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000001241 141.0
HKD1_k127_6075056_52 Thioredoxin-like - - - 0.000000000000000000000000000003179 134.0
HKD1_k127_6075056_53 iron-sulfur cluster assembly K07400,K13628,K15724 - - 0.00000000000000000000000000000385 121.0
HKD1_k127_6075056_54 DinB superfamily - - - 0.000000000000000000000000000005064 128.0
HKD1_k127_6075056_55 Universal stress protein family - - - 0.0000000000000000000000000006184 119.0
HKD1_k127_6075056_56 Pas domain - - - 0.000000000000000000000000002263 114.0
HKD1_k127_6075056_57 Protein of unknown function (DUF3047) - - - 0.00000000000000000000002113 114.0
HKD1_k127_6075056_58 EamA-like transporter family - - - 0.00000000000000000000008803 115.0
HKD1_k127_6075056_59 PFAM Copper resistance protein CopC K07156 - - 0.00000000000000000000816 97.0
HKD1_k127_6075056_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 496.0
HKD1_k127_6075056_60 pyridoxamine 5-phosphate - - - 0.00000000000000005905 90.0
HKD1_k127_6075056_61 Thioredoxin-like - - - 0.000000000002642 78.0
HKD1_k127_6075056_62 Participates in initiation and elongation during chromosome replication - - - 0.0000000001538 72.0
HKD1_k127_6075056_63 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000004868 71.0
HKD1_k127_6075056_64 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000007547 72.0
HKD1_k127_6075056_65 dksA traR - - - 0.00000004859 66.0
HKD1_k127_6075056_66 Winged helix DNA-binding domain - - - 0.00004202 57.0
HKD1_k127_6075056_67 Serine aminopeptidase, S33 - - - 0.00004272 55.0
HKD1_k127_6075056_69 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0007173 51.0
HKD1_k127_6075056_7 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 441.0
HKD1_k127_6075056_8 COG0111 Phosphoglycerate dehydrogenase and related K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 453.0
HKD1_k127_6075056_9 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 434.0
HKD1_k127_6098461_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 509.0
HKD1_k127_6098461_1 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 365.0
HKD1_k127_6098461_10 PFAM ABC transporter related K01995 - - 0.00000000000000000000000003724 111.0
HKD1_k127_6098461_11 - - - - 0.000000000000000000000001119 120.0
HKD1_k127_6098461_14 PFAM SMP-30 Gluconolaconase - - - 0.00007423 55.0
HKD1_k127_6098461_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 368.0
HKD1_k127_6098461_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 342.0
HKD1_k127_6098461_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 324.0
HKD1_k127_6098461_5 LssY C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 326.0
HKD1_k127_6098461_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 296.0
HKD1_k127_6098461_7 SMART Prolyl 4-hydroxylase, alpha subunit - - - 0.00000000000000000000000000000000504 146.0
HKD1_k127_6098461_8 PIN domain - - - 0.00000000000000000000000000000002608 133.0
HKD1_k127_6098461_9 (ABC) transporter - - - 0.00000000000000000000000000000003331 131.0
HKD1_k127_6132621_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 0.0 1124.0
HKD1_k127_6132621_1 Sugar (and other) transporter - - - 7.661e-244 758.0
HKD1_k127_6132621_10 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 535.0
HKD1_k127_6132621_11 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 503.0
HKD1_k127_6132621_12 PFAM Hydantoinase B oxoprolinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 533.0
HKD1_k127_6132621_13 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K08295 - 6.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 488.0
HKD1_k127_6132621_14 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 467.0
HKD1_k127_6132621_15 Oxidoreductase molybdopterin binding domain K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 438.0
HKD1_k127_6132621_16 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 419.0
HKD1_k127_6132621_17 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 438.0
HKD1_k127_6132621_18 Acyl-CoA dehydrogenase, C-terminal domain K19966 - 3.13.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 392.0
HKD1_k127_6132621_19 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 401.0
HKD1_k127_6132621_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.291e-212 677.0
HKD1_k127_6132621_20 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 362.0
HKD1_k127_6132621_21 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 352.0
HKD1_k127_6132621_22 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 356.0
HKD1_k127_6132621_23 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 367.0
HKD1_k127_6132621_24 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 361.0
HKD1_k127_6132621_25 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 357.0
HKD1_k127_6132621_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 355.0
HKD1_k127_6132621_27 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 341.0
HKD1_k127_6132621_28 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 322.0
HKD1_k127_6132621_29 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 316.0
HKD1_k127_6132621_3 NADH oxidase - - - 6.723e-205 649.0
HKD1_k127_6132621_30 ABC transporter (Permease K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 332.0
HKD1_k127_6132621_31 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 317.0
HKD1_k127_6132621_32 Binding-protein-dependent transport system inner membrane component K02034,K15586 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 299.0
HKD1_k127_6132621_33 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 304.0
HKD1_k127_6132621_34 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 304.0
HKD1_k127_6132621_35 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009015 283.0
HKD1_k127_6132621_36 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01479,K01480 - 3.5.3.11,3.5.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001645 284.0
HKD1_k127_6132621_37 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007787 287.0
HKD1_k127_6132621_38 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002043 279.0
HKD1_k127_6132621_39 (ABC) transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007488 267.0
HKD1_k127_6132621_4 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 1.112e-197 639.0
HKD1_k127_6132621_40 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000005044 270.0
HKD1_k127_6132621_41 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008936 243.0
HKD1_k127_6132621_42 Glucosamine-6-phosphate isomerase K01057,K02564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.1.1.31,3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000155 245.0
HKD1_k127_6132621_43 uracil-DNA glycosylase K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000003693 243.0
HKD1_k127_6132621_44 UDP-galactopyranose mutase K01854 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000005018 250.0
HKD1_k127_6132621_45 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000001858 235.0
HKD1_k127_6132621_46 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000004096 245.0
HKD1_k127_6132621_47 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000001585 238.0
HKD1_k127_6132621_48 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000001564 226.0
HKD1_k127_6132621_49 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000002664 229.0
HKD1_k127_6132621_5 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 620.0
HKD1_k127_6132621_50 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000006881 219.0
HKD1_k127_6132621_51 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000003605 214.0
HKD1_k127_6132621_52 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000001506 202.0
HKD1_k127_6132621_53 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000001146 210.0
HKD1_k127_6132621_54 - - - - 0.0000000000000000000000000000000000000000000000001624 201.0
HKD1_k127_6132621_55 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000001332 182.0
HKD1_k127_6132621_56 Thiopurine S-methyltransferase K00569 - 2.1.1.67 0.0000000000000000000000000000000000000000001797 169.0
HKD1_k127_6132621_57 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000003286 154.0
HKD1_k127_6132621_58 oxidation-reduction process - - - 0.0000000000000000000000000000000000004638 146.0
HKD1_k127_6132621_59 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000003044 151.0
HKD1_k127_6132621_6 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 616.0
HKD1_k127_6132621_60 3-hydroxyacyl-CoA dehydrogenase K00074,K15016,K15019 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0043956 1.1.1.157,1.1.1.35,4.2.1.116,4.2.1.17 0.00000000000000000000000000000000002687 147.0
HKD1_k127_6132621_61 serine-type endopeptidase activity K04772,K08372 - - 0.0000000000000000000000000000000001396 148.0
HKD1_k127_6132621_62 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000004865 140.0
HKD1_k127_6132621_63 SnoaL-like domain - - - 0.0000000000000000000000000000000006554 136.0
HKD1_k127_6132621_64 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000002829 137.0
HKD1_k127_6132621_65 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000001152 130.0
HKD1_k127_6132621_66 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000001764 122.0
HKD1_k127_6132621_67 - - - - 0.00000000000000000000000000004228 135.0
HKD1_k127_6132621_68 RNA recognition motif - - - 0.0000000000000000000000000001249 119.0
HKD1_k127_6132621_69 lactoylglutathione lyase activity K01759,K08234,K20431 - 4.4.1.5,5.1.3.33 0.000000000000000000000000000267 125.0
HKD1_k127_6132621_7 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 589.0
HKD1_k127_6132621_70 - - - - 0.000000000000000001673 100.0
HKD1_k127_6132621_71 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000052 77.0
HKD1_k127_6132621_72 Cyclin-dependent kinase inhibitor 3 (CDKN3) - - - 0.00000004663 66.0
HKD1_k127_6132621_73 - - - - 0.0000002762 64.0
HKD1_k127_6132621_74 FecR protein - - - 0.00001203 57.0
HKD1_k127_6132621_75 ParB-like nuclease domain - - - 0.0001929 53.0
HKD1_k127_6132621_76 homoserine dehydrogenase K00003 - 1.1.1.3 0.0005006 48.0
HKD1_k127_6132621_8 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 597.0
HKD1_k127_6132621_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 538.0
HKD1_k127_6173400_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 2.377e-287 894.0
HKD1_k127_6173400_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.105e-240 757.0
HKD1_k127_6173400_10 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 370.0
HKD1_k127_6173400_11 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 361.0
HKD1_k127_6173400_12 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 359.0
HKD1_k127_6173400_13 TIGRFAM amidase, hydantoinase carbamoylase K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 339.0
HKD1_k127_6173400_14 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 308.0
HKD1_k127_6173400_15 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 309.0
HKD1_k127_6173400_16 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 293.0
HKD1_k127_6173400_17 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 297.0
HKD1_k127_6173400_18 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008913 283.0
HKD1_k127_6173400_19 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004312 282.0
HKD1_k127_6173400_2 Gamma-glutamyltranspeptidase - - - 2.507e-200 640.0
HKD1_k127_6173400_20 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000003438 236.0
HKD1_k127_6173400_21 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000001196 218.0
HKD1_k127_6173400_22 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000004499 213.0
HKD1_k127_6173400_23 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000001661 193.0
HKD1_k127_6173400_24 gamma-glutamyl-gamma-aminobutyrate hydrolase activity K07010 - - 0.00000000000000000000000000000000000000000000000004749 192.0
HKD1_k127_6173400_25 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000006897 173.0
HKD1_k127_6173400_26 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000004695 163.0
HKD1_k127_6173400_27 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000003898 168.0
HKD1_k127_6173400_28 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000003278 161.0
HKD1_k127_6173400_29 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000005326 136.0
HKD1_k127_6173400_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.132,1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 584.0
HKD1_k127_6173400_30 PFAM NUDIX hydrolase - - - 0.0000000000000000000000003944 123.0
HKD1_k127_6173400_31 Peptidase, M23 - - - 0.0000000000000001209 95.0
HKD1_k127_6173400_32 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000001489 86.0
HKD1_k127_6173400_33 Trm112p-like protein K09791 - - 0.000000000182 67.0
HKD1_k127_6173400_34 Archease protein family (MTH1598/TM1083) - - - 0.00000001132 68.0
HKD1_k127_6173400_35 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000001305 59.0
HKD1_k127_6173400_36 outer membrane protein protective antigen - - - 0.00001032 59.0
HKD1_k127_6173400_37 Type II transport protein GspH K08084 - - 0.00007975 52.0
HKD1_k127_6173400_4 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 554.0
HKD1_k127_6173400_5 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 479.0
HKD1_k127_6173400_6 Aminotransferase class-III K00822,K00833 - 2.6.1.18,2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 454.0
HKD1_k127_6173400_7 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 446.0
HKD1_k127_6173400_8 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 419.0
HKD1_k127_6173400_9 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 408.0
HKD1_k127_6226449_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 0.0 1067.0
HKD1_k127_6226449_1 Transaldolase/Fructose-6-phosphate aldolase K00616,K13810 - 2.2.1.2,5.3.1.9 4.195e-236 745.0
HKD1_k127_6226449_10 Belongs to the FBPase class 1 family K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001115 277.0
HKD1_k127_6226449_11 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000008871 237.0
HKD1_k127_6226449_12 Acetyltransferase (GNAT) family - - - 0.00000000000004362 85.0
HKD1_k127_6226449_13 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K12276 - - 0.000000000225 73.0
HKD1_k127_6226449_14 long-chain fatty acid transporting porin activity - - - 0.00005778 55.0
HKD1_k127_6226449_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.565e-201 640.0
HKD1_k127_6226449_3 lyase activity K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 494.0
HKD1_k127_6226449_4 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 486.0
HKD1_k127_6226449_5 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 382.0
HKD1_k127_6226449_6 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 359.0
HKD1_k127_6226449_7 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 364.0
HKD1_k127_6226449_8 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 343.0
HKD1_k127_6226449_9 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 321.0
HKD1_k127_6238453_0 Sulfatase K01130 - 3.1.6.1 0.0 1387.0
HKD1_k127_6238453_1 The reductase domain is required for electron transfer from NADP to cytochrome P450 K00493,K14338 - 1.14.14.1,1.6.2.4 0.0 1212.0
HKD1_k127_6238453_10 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 504.0
HKD1_k127_6238453_11 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 485.0
HKD1_k127_6238453_12 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 435.0
HKD1_k127_6238453_13 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 413.0
HKD1_k127_6238453_14 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 424.0
HKD1_k127_6238453_15 Hydantoinase/oxoprolinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 423.0
HKD1_k127_6238453_16 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 400.0
HKD1_k127_6238453_17 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 400.0
HKD1_k127_6238453_18 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 402.0
HKD1_k127_6238453_19 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 389.0
HKD1_k127_6238453_2 COG0457 FOG TPR repeat - - - 4.039e-285 884.0
HKD1_k127_6238453_20 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 394.0
HKD1_k127_6238453_21 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 372.0
HKD1_k127_6238453_22 Belongs to the amidase family K01426 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 379.0
HKD1_k127_6238453_23 PFAM fumarylacetoacetate (FAA) hydrolase K16856,K18336 - 4.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 366.0
HKD1_k127_6238453_24 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 353.0
HKD1_k127_6238453_25 dioxygenase activity K18565 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 344.0
HKD1_k127_6238453_26 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 329.0
HKD1_k127_6238453_27 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 327.0
HKD1_k127_6238453_28 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 321.0
HKD1_k127_6238453_29 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 309.0
HKD1_k127_6238453_3 amine dehydrogenase activity K03418 - 3.5.1.56 4.86e-255 812.0
HKD1_k127_6238453_30 Transketolase, thiamine diphosphate binding domain K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 312.0
HKD1_k127_6238453_31 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 291.0
HKD1_k127_6238453_32 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009949 291.0
HKD1_k127_6238453_33 Flagellar Assembly Protein A K09749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007653 271.0
HKD1_k127_6238453_34 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004658 277.0
HKD1_k127_6238453_35 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002094 273.0
HKD1_k127_6238453_36 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007629 244.0
HKD1_k127_6238453_37 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002297 263.0
HKD1_k127_6238453_38 N-terminal TM domain of oligopeptide transport permease C - - - 0.0000000000000000000000000000000000000000000000000000000000000000002159 239.0
HKD1_k127_6238453_39 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000002446 254.0
HKD1_k127_6238453_4 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 5.91e-221 691.0
HKD1_k127_6238453_40 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01464,K01465 - 3.5.2.2,3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000003086 246.0
HKD1_k127_6238453_41 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000001132 231.0
HKD1_k127_6238453_42 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000004355 226.0
HKD1_k127_6238453_43 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000534 223.0
HKD1_k127_6238453_44 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000001265 212.0
HKD1_k127_6238453_45 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000001354 206.0
HKD1_k127_6238453_46 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000001808 195.0
HKD1_k127_6238453_47 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000006342 187.0
HKD1_k127_6238453_48 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000252 182.0
HKD1_k127_6238453_49 - - - - 0.0000000000000000000000000000000000000000002345 172.0
HKD1_k127_6238453_5 Phosphoesterase family - - - 5.204e-210 664.0
HKD1_k127_6238453_50 coenzyme F390 K01912 - 6.2.1.30 0.00000000000000000000000000000000000000001411 177.0
HKD1_k127_6238453_51 oxidation-reduction process K09022 - 3.5.99.10 0.0000000000000000000000000000000000000113 154.0
HKD1_k127_6238453_52 nuclease - - - 0.000000000000000000000000000000000002713 144.0
HKD1_k127_6238453_54 Type VI secretion system effector, Hcp K11903 - - 0.00000000000000000000001664 116.0
HKD1_k127_6238453_55 glycosyl transferase group 1 - - - 0.00000000000000000001873 106.0
HKD1_k127_6238453_56 endoribonuclease L-PSP - - - 0.0000000000000000002346 93.0
HKD1_k127_6238453_57 Domain of unknown function (DUF4440) - - - 0.00000000002551 68.0
HKD1_k127_6238453_58 oxidoreductase activity - - - 0.000001751 62.0
HKD1_k127_6238453_59 - - - - 0.000008665 53.0
HKD1_k127_6238453_6 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 589.0
HKD1_k127_6238453_60 NMT1-like family K02051 - - 0.00009064 54.0
HKD1_k127_6238453_61 serine-type endopeptidase activity - - - 0.000126 55.0
HKD1_k127_6238453_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 557.0
HKD1_k127_6238453_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15785 - 2.6.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 552.0
HKD1_k127_6238453_9 PFAM Transketolase central region K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 523.0
HKD1_k127_6245143_0 Protein of unknown function, DUF255 K06888 - - 4.134e-242 782.0
HKD1_k127_6245143_1 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 601.0
HKD1_k127_6245143_10 molybdopterin K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 362.0
HKD1_k127_6245143_11 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 317.0
HKD1_k127_6245143_12 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 302.0
HKD1_k127_6245143_13 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 306.0
HKD1_k127_6245143_14 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 304.0
HKD1_k127_6245143_15 PFAM aminotransferase, class I K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001632 280.0
HKD1_k127_6245143_16 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002071 271.0
HKD1_k127_6245143_17 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000101 286.0
HKD1_k127_6245143_18 PFAM UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000001206 269.0
HKD1_k127_6245143_19 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000734 273.0
HKD1_k127_6245143_2 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 593.0
HKD1_k127_6245143_20 Belongs to the hyi family K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000001582 272.0
HKD1_k127_6245143_21 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001486 245.0
HKD1_k127_6245143_22 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000001139 239.0
HKD1_k127_6245143_23 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000006205 241.0
HKD1_k127_6245143_24 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000005681 228.0
HKD1_k127_6245143_25 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000000006667 216.0
HKD1_k127_6245143_26 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000005231 205.0
HKD1_k127_6245143_27 domain protein K01992,K06994 - - 0.000000000000000000000000000000000000000000000000000007847 210.0
HKD1_k127_6245143_28 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000009629 188.0
HKD1_k127_6245143_29 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000001589 189.0
HKD1_k127_6245143_3 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 487.0
HKD1_k127_6245143_30 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000001639 186.0
HKD1_k127_6245143_31 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000003896 178.0
HKD1_k127_6245143_32 TatD related DNase K03424 - - 0.000000000000000000000000000000008038 137.0
HKD1_k127_6245143_33 Molybdopterin converting factor, small subunit K03636 - - 0.00000000000000000000000000000002518 127.0
HKD1_k127_6245143_34 PFAM RNA recognition motif - - - 0.0000000000000000000000004827 108.0
HKD1_k127_6245143_35 NUDIX domain K03574,K03575 - 3.6.1.55 0.000000000000000000000001723 116.0
HKD1_k127_6245143_36 PFAM Rieske 2Fe-2S domain protein - - - 0.0000000000000000000007469 106.0
HKD1_k127_6245143_37 HemY protein K02498,K20543 - - 0.000000000000000000007339 104.0
HKD1_k127_6245143_38 ribonuclease BN K07058 - - 0.00000000000000001082 98.0
HKD1_k127_6245143_39 thiamine biosynthesis protein ThiS K03154 - - 0.0000000003455 64.0
HKD1_k127_6245143_4 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 477.0
HKD1_k127_6245143_40 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein - - - 0.0000001191 65.0
HKD1_k127_6245143_41 Domain of unknown function (DUF309) K09763 - - 0.000003397 60.0
HKD1_k127_6245143_42 RDD family - - - 0.000004365 59.0
HKD1_k127_6245143_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 370.0
HKD1_k127_6245143_6 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 382.0
HKD1_k127_6245143_7 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009158 367.0
HKD1_k127_6245143_8 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 347.0
HKD1_k127_6245143_9 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 347.0
HKD1_k127_6275870_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1698.0
HKD1_k127_6275870_1 ABC transporter - - - 3.951e-260 812.0
HKD1_k127_6275870_10 Copper binding proteins, plastocyanin/azurin family K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 564.0
HKD1_k127_6275870_100 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000005066 102.0
HKD1_k127_6275870_101 - - - - 0.000000000000000000006025 105.0
HKD1_k127_6275870_102 RNA recognition motif - - - 0.00000000000000000006414 104.0
HKD1_k127_6275870_103 chaperone-mediated protein complex assembly - - - 0.000000000000000002638 100.0
HKD1_k127_6275870_104 FeS assembly SUF system protein - - - 0.000000000000000002952 101.0
HKD1_k127_6275870_105 Glutaredoxin - - - 0.0000000000000005805 81.0
HKD1_k127_6275870_106 Electron transport protein SCO1 SenC K07152 - - 0.000000000000008374 87.0
HKD1_k127_6275870_107 - - - - 0.00000000000001499 85.0
HKD1_k127_6275870_108 ABC transporter substrate binding protein K01989 - - 0.00000000000002922 79.0
HKD1_k127_6275870_109 Bacterial regulatory proteins, tetR family - - - 0.0000000000000527 81.0
HKD1_k127_6275870_11 dipeptidyl-peptidase activity K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 550.0
HKD1_k127_6275870_110 - - - - 0.000000000007816 78.0
HKD1_k127_6275870_112 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000006988 67.0
HKD1_k127_6275870_113 Transglutaminase-like superfamily - - - 0.000000004215 63.0
HKD1_k127_6275870_114 Thioredoxin-like - - - 0.0000002415 58.0
HKD1_k127_6275870_115 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000002661 63.0
HKD1_k127_6275870_116 - - - - 0.00001821 53.0
HKD1_k127_6275870_117 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0003497 47.0
HKD1_k127_6275870_12 CHASE2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 550.0
HKD1_k127_6275870_13 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 518.0
HKD1_k127_6275870_14 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 477.0
HKD1_k127_6275870_15 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 447.0
HKD1_k127_6275870_16 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 454.0
HKD1_k127_6275870_17 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 419.0
HKD1_k127_6275870_18 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 401.0
HKD1_k127_6275870_19 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 418.0
HKD1_k127_6275870_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5.945e-230 739.0
HKD1_k127_6275870_20 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 389.0
HKD1_k127_6275870_21 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 383.0
HKD1_k127_6275870_22 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 378.0
HKD1_k127_6275870_23 MscS Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 379.0
HKD1_k127_6275870_24 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 380.0
HKD1_k127_6275870_25 COG0477 Permeases of the major facilitator superfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 367.0
HKD1_k127_6275870_26 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 364.0
HKD1_k127_6275870_27 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008296 359.0
HKD1_k127_6275870_28 Fe-S oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 364.0
HKD1_k127_6275870_29 gluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 344.0
HKD1_k127_6275870_3 heme-copper terminal oxidase activity K02274 - 1.9.3.1 2.73e-209 665.0
HKD1_k127_6275870_30 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 346.0
HKD1_k127_6275870_31 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 332.0
HKD1_k127_6275870_32 Belongs to the ABC transporter superfamily K02032,K10823,K12372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 345.0
HKD1_k127_6275870_33 TIM-barrel fold metal-dependent hydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 335.0
HKD1_k127_6275870_34 TIGRFAM CitB domain protein K13795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 336.0
HKD1_k127_6275870_35 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 343.0
HKD1_k127_6275870_36 Histidine kinase K02668,K07709,K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 338.0
HKD1_k127_6275870_37 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 332.0
HKD1_k127_6275870_38 benzoyl-CoA reductase K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 307.0
HKD1_k127_6275870_39 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 293.0
HKD1_k127_6275870_4 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 3.779e-208 651.0
HKD1_k127_6275870_40 chaperone-mediated protein complex assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 311.0
HKD1_k127_6275870_41 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 297.0
HKD1_k127_6275870_42 R COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 321.0
HKD1_k127_6275870_43 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 297.0
HKD1_k127_6275870_44 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000442 289.0
HKD1_k127_6275870_45 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002117 286.0
HKD1_k127_6275870_46 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002571 281.0
HKD1_k127_6275870_47 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006386 296.0
HKD1_k127_6275870_48 COGs COG0673 dehydrogenase and related protein K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002538 286.0
HKD1_k127_6275870_49 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005446 297.0
HKD1_k127_6275870_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 1.257e-195 617.0
HKD1_k127_6275870_50 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000039 276.0
HKD1_k127_6275870_51 benzoyl-CoA reductase K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003796 278.0
HKD1_k127_6275870_52 NAD dependent epimerase/dehydratase family K07535 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000494 272.0
HKD1_k127_6275870_53 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002409 271.0
HKD1_k127_6275870_54 Creatinine amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003904 267.0
HKD1_k127_6275870_55 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001677 285.0
HKD1_k127_6275870_56 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004625 261.0
HKD1_k127_6275870_57 B12 binding domain K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000003972 258.0
HKD1_k127_6275870_58 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007052 250.0
HKD1_k127_6275870_59 TIGRFAM membrane complex biogenesis protein, BtpA family K06971 - - 0.000000000000000000000000000000000000000000000000000000000000000000001006 269.0
HKD1_k127_6275870_6 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 607.0
HKD1_k127_6275870_60 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003584 249.0
HKD1_k127_6275870_61 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000008161 253.0
HKD1_k127_6275870_62 TIGRFAM DNA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000039 244.0
HKD1_k127_6275870_63 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000002291 241.0
HKD1_k127_6275870_64 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002978 233.0
HKD1_k127_6275870_65 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000001207 244.0
HKD1_k127_6275870_66 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000001792 245.0
HKD1_k127_6275870_67 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000007742 239.0
HKD1_k127_6275870_68 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000002567 217.0
HKD1_k127_6275870_69 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000009664 234.0
HKD1_k127_6275870_7 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 605.0
HKD1_k127_6275870_70 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000001877 226.0
HKD1_k127_6275870_71 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000004284 213.0
HKD1_k127_6275870_72 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000001111 223.0
HKD1_k127_6275870_73 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000003785 228.0
HKD1_k127_6275870_74 cytochrome c oxidase - - - 0.0000000000000000000000000000000000000000000000000001455 200.0
HKD1_k127_6275870_75 Pas domain - - - 0.000000000000000000000000000000000000000000000000001205 191.0
HKD1_k127_6275870_76 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059,K21883 - 1.1.1.100,1.1.1.401 0.000000000000000000000000000000000000000000000000001311 197.0
HKD1_k127_6275870_77 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000001481 203.0
HKD1_k127_6275870_78 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000536 191.0
HKD1_k127_6275870_79 - - - - 0.0000000000000000000000000000000000000000000000006698 186.0
HKD1_k127_6275870_8 FAD dependent oxidoreductase K13796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 566.0
HKD1_k127_6275870_80 Pfam:Methyltransf_6 - - - 0.0000000000000000000000000000000000000000000001106 190.0
HKD1_k127_6275870_81 Carbohydrate-selective porin, OprB family K07267 - - 0.000000000000000000000000000000000000000004562 175.0
HKD1_k127_6275870_82 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000004196 164.0
HKD1_k127_6275870_83 - - - - 0.0000000000000000000000000000000000000004792 156.0
HKD1_k127_6275870_84 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000006325 151.0
HKD1_k127_6275870_86 PFAM Cyclic nucleotide-binding K10914,K21564 - - 0.00000000000000000000000000000000000023 150.0
HKD1_k127_6275870_87 conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000002833 151.0
HKD1_k127_6275870_88 protein conserved in bacteria - - - 0.0000000000000000000000000000000000002921 157.0
HKD1_k127_6275870_89 TIGRFAM Urea carboxylase-associated protein 1 K09967 - - 0.000000000000000000000000000000000000913 153.0
HKD1_k127_6275870_9 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 560.0
HKD1_k127_6275870_90 Ethanolamine utilisation protein EutQ - - - 0.000000000000000000000000000000000003714 143.0
HKD1_k127_6275870_91 PFAM alanine racemase domain protein K20757 - 4.3.1.27 0.0000000000000000000000000000000001054 134.0
HKD1_k127_6275870_92 NIPSNAP - - - 0.000000000000000000000000000000006512 132.0
HKD1_k127_6275870_93 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000003914 133.0
HKD1_k127_6275870_94 FecR protein - - - 0.00000000000000000000000000000005455 130.0
HKD1_k127_6275870_95 amine dehydrogenase activity K13730 - - 0.0000000000000000000000000000004704 139.0
HKD1_k127_6275870_96 STAS domain K06378 - - 0.00000000000000000000000001243 116.0
HKD1_k127_6275870_97 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000001367 113.0
HKD1_k127_6275870_98 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000002106 113.0
HKD1_k127_6275870_99 Histidine kinase-like ATPase domain - - - 0.0000000000000000000003931 101.0
HKD1_k127_6370649_0 mandelate racemase muconate lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 515.0
HKD1_k127_6370649_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 528.0
HKD1_k127_6370649_10 MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 351.0
HKD1_k127_6370649_11 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 323.0
HKD1_k127_6370649_12 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 304.0
HKD1_k127_6370649_13 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 303.0
HKD1_k127_6370649_14 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 317.0
HKD1_k127_6370649_15 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006998 260.0
HKD1_k127_6370649_16 COGs COG0747 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007563 262.0
HKD1_k127_6370649_17 Carbon-nitrogen hydrolase K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000003228 240.0
HKD1_k127_6370649_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000003255 218.0
HKD1_k127_6370649_19 Acetamidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000005633 221.0
HKD1_k127_6370649_2 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 505.0
HKD1_k127_6370649_20 KR domain - - - 0.00000000000000000000000000000000000000000000000000000006679 204.0
HKD1_k127_6370649_21 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000003214 189.0
HKD1_k127_6370649_22 PFAM Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000119 194.0
HKD1_k127_6370649_23 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000000004283 155.0
HKD1_k127_6370649_24 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000006725 164.0
HKD1_k127_6370649_25 - - - - 0.000000000000000000000000000000000005976 158.0
HKD1_k127_6370649_26 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000001289 147.0
HKD1_k127_6370649_27 cyclic nucleotide binding K04739,K10914 - - 0.00000000000000000000121 112.0
HKD1_k127_6370649_28 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000001623 99.0
HKD1_k127_6370649_29 - - - - 0.000000000000000000005411 108.0
HKD1_k127_6370649_3 Peptidase family M20/M25/M40 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 485.0
HKD1_k127_6370649_30 MazG nucleotide pyrophosphohydrolase domain - - - 0.000000000000002758 85.0
HKD1_k127_6370649_31 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000003202 85.0
HKD1_k127_6370649_32 Protein of unknown function (DUF1285) K09986 - - 0.000000000222 69.0
HKD1_k127_6370649_33 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - 0.00009981 49.0
HKD1_k127_6370649_4 FMN-dependent dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 455.0
HKD1_k127_6370649_5 protein-(glutamine-N5) methyltransferase activity K00543,K16130,K18896,K18897,K21515 - 2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 402.0
HKD1_k127_6370649_6 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18983 - 5.5.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 382.0
HKD1_k127_6370649_7 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 385.0
HKD1_k127_6370649_8 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 392.0
HKD1_k127_6370649_9 PFAM Dehydrogenase, E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 353.0
HKD1_k127_6424952_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0 1277.0
HKD1_k127_6424952_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.661e-224 766.0
HKD1_k127_6424952_10 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 370.0
HKD1_k127_6424952_11 KR domain K22185 - 1.1.1.175 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 355.0
HKD1_k127_6424952_12 Flavin containing amine oxidoreductase K00231,K00274 - 1.3.3.15,1.3.3.4,1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 356.0
HKD1_k127_6424952_13 5'-3' exonuclease, N-terminal resolvase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 328.0
HKD1_k127_6424952_14 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 308.0
HKD1_k127_6424952_15 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 312.0
HKD1_k127_6424952_16 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007951 283.0
HKD1_k127_6424952_17 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006915 283.0
HKD1_k127_6424952_18 Aldose 1-epimerase K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000181 278.0
HKD1_k127_6424952_19 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04101 - 1.13.11.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000005354 285.0
HKD1_k127_6424952_2 cellulose binding - - - 1.577e-221 690.0
HKD1_k127_6424952_20 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004612 271.0
HKD1_k127_6424952_21 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000023 256.0
HKD1_k127_6424952_22 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009391 243.0
HKD1_k127_6424952_23 2Fe-2S -binding domain protein K00256,K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000002583 231.0
HKD1_k127_6424952_24 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000005195 246.0
HKD1_k127_6424952_25 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000002327 222.0
HKD1_k127_6424952_26 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000003446 235.0
HKD1_k127_6424952_27 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000001005 214.0
HKD1_k127_6424952_28 regulatory protein, gntR - - - 0.00000000000000000000000000000000000000000000000000000005653 209.0
HKD1_k127_6424952_29 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000002055 201.0
HKD1_k127_6424952_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 615.0
HKD1_k127_6424952_30 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000004303 200.0
HKD1_k127_6424952_31 IMG reference gene - - - 0.00000000000000000000000000000000000000000000000002986 200.0
HKD1_k127_6424952_32 Fucosyltransferase which adds the fucose moiety of the nod factor on its terminal reducing N-acetylglucosamine end. Uses GDP-fucose as the donor group - - - 0.00000000000000000000000000000000000000000000004059 189.0
HKD1_k127_6424952_33 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000006134 170.0
HKD1_k127_6424952_34 domain protein - - - 0.00000000000000000000000000000000000000001799 161.0
HKD1_k127_6424952_35 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000004426 173.0
HKD1_k127_6424952_36 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000000001564 151.0
HKD1_k127_6424952_37 domain, Protein - - - 0.0000000000000000000000000000000000001232 165.0
HKD1_k127_6424952_38 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000002591 154.0
HKD1_k127_6424952_39 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000008964 147.0
HKD1_k127_6424952_4 Belongs to the CinA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 612.0
HKD1_k127_6424952_40 SnoaL-like domain - - - 0.0000000000000000000000000000000199 130.0
HKD1_k127_6424952_41 COG0831 Urea amidohydrolase (urease) gamma subunit - - - 0.00000000000000000000000003097 118.0
HKD1_k127_6424952_42 GYD domain - - - 0.000000000000000000000001425 114.0
HKD1_k127_6424952_43 belongs to the urease gamma subunit family K14048 - 3.5.1.5 0.000000000000000000000009639 110.0
HKD1_k127_6424952_44 Glycosyltransferase Family 4 - - - 0.000000000000000000007457 106.0
HKD1_k127_6424952_45 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000001266 77.0
HKD1_k127_6424952_46 - - - - 0.00000002968 66.0
HKD1_k127_6424952_47 - - - - 0.0000002052 55.0
HKD1_k127_6424952_49 glycosyl transferase group 1 - - - 0.0000007696 61.0
HKD1_k127_6424952_5 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 567.0
HKD1_k127_6424952_50 - - - - 0.00004545 51.0
HKD1_k127_6424952_51 - - - - 0.00008038 53.0
HKD1_k127_6424952_6 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 453.0
HKD1_k127_6424952_7 Belongs to the proline racemase family K01777 - 5.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 445.0
HKD1_k127_6424952_8 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 422.0
HKD1_k127_6424952_9 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 404.0
HKD1_k127_657924_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 7.179e-208 659.0
HKD1_k127_657924_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.959e-207 661.0
HKD1_k127_657924_2 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 395.0
HKD1_k127_657924_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 299.0
HKD1_k127_657924_4 TPM domain - - - 0.000000000000000000000000000000001836 135.0
HKD1_k127_6596401_0 Hydantoinase/oxoprolinase - - - 8.729e-308 957.0
HKD1_k127_6596401_1 Hydantoinase B/oxoprolinase - - - 1.54e-283 882.0
HKD1_k127_6596401_10 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000004034 162.0
HKD1_k127_6596401_11 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000001784 138.0
HKD1_k127_6596401_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K14188 GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 0.00000000000000000001721 106.0
HKD1_k127_6596401_2 D-alanine [D-alanyl carrier protein] ligase activity K03367 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 569.0
HKD1_k127_6596401_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 460.0
HKD1_k127_6596401_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 432.0
HKD1_k127_6596401_5 negative regulation of protein lipidation K03739 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 407.0
HKD1_k127_6596401_6 Glycosyl transferase family 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 358.0
HKD1_k127_6596401_7 Methyltransferase FkbM family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 358.0
HKD1_k127_6596401_8 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) K03740 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 294.0
HKD1_k127_6596401_9 - - - - 0.0000000000000000000000000000000000000000000256 185.0
HKD1_k127_6733135_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000001053 235.0
HKD1_k127_6733135_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000009801 186.0
HKD1_k127_6733135_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000002616 151.0
HKD1_k127_6733135_3 polysaccharide deacetylase - - - 0.000000000000000000000000000004894 130.0
HKD1_k127_6733135_4 NMT1-like family - - - 0.000000000002576 74.0
HKD1_k127_7064551_0 Sulfatase - - - 0.0 1007.0
HKD1_k127_7064551_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 400.0
HKD1_k127_7064551_10 Protein of unknown function, DUF481 - - - 0.000000000000005509 85.0
HKD1_k127_7064551_3 HTH-like domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 288.0
HKD1_k127_7064551_4 DNA integration K07497 - - 0.0000000000000000000000000000000000000000000000003326 192.0
HKD1_k127_7064551_5 DNA polymerase family A K02334 - 2.7.7.7 0.00000000000000000000000000000002337 145.0
HKD1_k127_7064551_7 Transcriptional regulator K04033 - - 0.00000000000000000000000000002282 130.0
HKD1_k127_7064551_8 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000004803 113.0
HKD1_k127_7064551_9 PFAM transposase IS3 IS911 family protein K07483 - - 0.0000000000000001485 86.0
HKD1_k127_7071196_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1345.0
HKD1_k127_7071196_1 AcrB/AcrD/AcrF family - - - 0.0 1176.0
HKD1_k127_7071196_10 adenosylhomocysteinase activity K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 585.0
HKD1_k127_7071196_100 Protein of unknown function (DUF2889) - - - 0.00000000422 69.0
HKD1_k127_7071196_101 Lipopolysaccharide-assembly, LptC-related K09774,K11719 - - 0.00000007 63.0
HKD1_k127_7071196_102 Domain of unknown function (DUF4149) - - - 0.000001386 58.0
HKD1_k127_7071196_103 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00001902 57.0
HKD1_k127_7071196_104 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0003659 52.0
HKD1_k127_7071196_105 Redoxin K03564 - 1.11.1.15 0.000498 51.0
HKD1_k127_7071196_11 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005646 579.0
HKD1_k127_7071196_12 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 532.0
HKD1_k127_7071196_13 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 529.0
HKD1_k127_7071196_14 ABC transporter transmembrane region K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 558.0
HKD1_k127_7071196_15 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 513.0
HKD1_k127_7071196_16 MacB-like periplasmic core domain K02004,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 512.0
HKD1_k127_7071196_17 secondary active sulfate transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 490.0
HKD1_k127_7071196_18 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 462.0
HKD1_k127_7071196_19 ABC transporter transmembrane region K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 471.0
HKD1_k127_7071196_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1052.0
HKD1_k127_7071196_20 TIGRFAM iron-sulfur cluster binding protein K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 454.0
HKD1_k127_7071196_21 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 409.0
HKD1_k127_7071196_22 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671,K22345 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 391.0
HKD1_k127_7071196_23 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 383.0
HKD1_k127_7071196_24 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 366.0
HKD1_k127_7071196_25 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 392.0
HKD1_k127_7071196_26 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 351.0
HKD1_k127_7071196_27 Belongs to the SIS family. GutQ KpsF subfamily K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 357.0
HKD1_k127_7071196_28 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 349.0
HKD1_k127_7071196_29 peptidase dimerisation domain protein K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 350.0
HKD1_k127_7071196_3 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 2.96e-322 1039.0
HKD1_k127_7071196_30 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 344.0
HKD1_k127_7071196_31 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 338.0
HKD1_k127_7071196_32 Permease YjgP YjgQ family protein K07091,K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 346.0
HKD1_k127_7071196_33 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 340.0
HKD1_k127_7071196_34 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 333.0
HKD1_k127_7071196_35 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 326.0
HKD1_k127_7071196_36 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 303.0
HKD1_k127_7071196_37 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 295.0
HKD1_k127_7071196_38 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 310.0
HKD1_k127_7071196_39 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001634 302.0
HKD1_k127_7071196_4 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 5.347e-317 1006.0
HKD1_k127_7071196_40 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000252 287.0
HKD1_k127_7071196_41 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004475 280.0
HKD1_k127_7071196_42 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000734 292.0
HKD1_k127_7071196_43 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006553 284.0
HKD1_k127_7071196_44 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001272 273.0
HKD1_k127_7071196_45 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000004861 268.0
HKD1_k127_7071196_46 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000001748 273.0
HKD1_k127_7071196_47 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000009787 255.0
HKD1_k127_7071196_48 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002831 270.0
HKD1_k127_7071196_49 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003881 250.0
HKD1_k127_7071196_5 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.38e-281 885.0
HKD1_k127_7071196_50 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000004763 275.0
HKD1_k127_7071196_51 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001419 258.0
HKD1_k127_7071196_52 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002319 258.0
HKD1_k127_7071196_53 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000003367 241.0
HKD1_k127_7071196_54 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003718 248.0
HKD1_k127_7071196_55 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000001249 252.0
HKD1_k127_7071196_56 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000007766 238.0
HKD1_k127_7071196_57 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000001052 252.0
HKD1_k127_7071196_58 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000006395 222.0
HKD1_k127_7071196_59 HlyD family secretion protein K03585 - - 0.0000000000000000000000000000000000000000000000000000000000004985 234.0
HKD1_k127_7071196_6 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.746e-276 871.0
HKD1_k127_7071196_60 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000003506 213.0
HKD1_k127_7071196_61 CBS domain containing protein K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000004691 223.0
HKD1_k127_7071196_62 Belongs to the UPF0282 family K07022 - - 0.0000000000000000000000000000000000000000000000000000000008481 212.0
HKD1_k127_7071196_63 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000001541 232.0
HKD1_k127_7071196_64 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000003014 219.0
HKD1_k127_7071196_65 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000000003149 189.0
HKD1_k127_7071196_66 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000002035 200.0
HKD1_k127_7071196_67 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000001282 185.0
HKD1_k127_7071196_68 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000000000005156 184.0
HKD1_k127_7071196_69 sh3 domain protein - - - 0.0000000000000000000000000000000000000000000008229 187.0
HKD1_k127_7071196_7 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 1.255e-244 769.0
HKD1_k127_7071196_70 Histidine kinase - - - 0.00000000000000000000000000000000000000000001256 185.0
HKD1_k127_7071196_71 ligase activity - - - 0.000000000000000000000000000000000000000000756 169.0
HKD1_k127_7071196_72 protein domain associated with K03595,K06883,K06946 - - 0.0000000000000000000000000000000000000001163 164.0
HKD1_k127_7071196_73 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000003012 156.0
HKD1_k127_7071196_74 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000001957 160.0
HKD1_k127_7071196_75 PHP domain protein - - - 0.00000000000000000000000000000000000001624 166.0
HKD1_k127_7071196_76 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000001068 156.0
HKD1_k127_7071196_78 peroxiredoxin activity K03386,K03564,K16922 - 1.11.1.15 0.0000000000000000000000000000000001608 138.0
HKD1_k127_7071196_79 Putative sugar-binding domain - - - 0.000000000000000000000000000000004429 141.0
HKD1_k127_7071196_8 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 6.994e-209 663.0
HKD1_k127_7071196_80 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000415 130.0
HKD1_k127_7071196_81 prohibitin homologues - - - 0.000000000000000000000000000003043 133.0
HKD1_k127_7071196_82 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000189 117.0
HKD1_k127_7071196_83 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000002173 117.0
HKD1_k127_7071196_84 Protein of unknown function DUF126 - - - 0.000000000000000000000000006421 129.0
HKD1_k127_7071196_85 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000001924 106.0
HKD1_k127_7071196_86 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.00000000000000000000007969 106.0
HKD1_k127_7071196_87 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000002297 99.0
HKD1_k127_7071196_88 LUD domain - - - 0.000000000000000000003598 107.0
HKD1_k127_7071196_89 domain protein - - - 0.00000000000000000001181 106.0
HKD1_k127_7071196_9 Beta-lactamase - - - 5.933e-199 646.0
HKD1_k127_7071196_90 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000002542 101.0
HKD1_k127_7071196_91 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000007541 102.0
HKD1_k127_7071196_92 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000002115 96.0
HKD1_k127_7071196_93 Protein conserved in bacteria K09986 - - 0.000000000000000001146 99.0
HKD1_k127_7071196_94 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000407 98.0
HKD1_k127_7071196_95 HAD-hyrolase-like K08723 - 3.1.3.5 0.0000000000000008131 87.0
HKD1_k127_7071196_96 - - - - 0.000000000000001672 91.0
HKD1_k127_7071196_97 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000006584 81.0
HKD1_k127_7071196_98 Lipopolysaccharide-assembly - - - 0.000000000002474 77.0
HKD1_k127_7071196_99 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000000003305 68.0
HKD1_k127_7102818_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 379.0
HKD1_k127_7102818_1 ABC-type polar amino acid transport system ATPase component K09972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 325.0
HKD1_k127_7102818_10 ABC transporter, phosphonate, periplasmic substrate-binding protein K02030,K10039 - - 0.00000000000000000000000000000001888 139.0
HKD1_k127_7102818_11 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000002597 129.0
HKD1_k127_7102818_12 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000000007656 100.0
HKD1_k127_7102818_13 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000002038 106.0
HKD1_k127_7102818_15 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000002357 91.0
HKD1_k127_7102818_2 mandelate racemase muconate lactonizing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 304.0
HKD1_k127_7102818_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000009677 204.0
HKD1_k127_7102818_4 pathogenesis - - - 0.00000000000000000000000000000000000000000000000000006271 198.0
HKD1_k127_7102818_5 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000001444 198.0
HKD1_k127_7102818_6 Binding-protein-dependent transport system inner membrane component K02029 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000005123 177.0
HKD1_k127_7102818_7 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.000000000000000000000000000000000000000831 155.0
HKD1_k127_7102818_8 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000001623 154.0
HKD1_k127_7102818_9 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000006629 147.0
HKD1_k127_7107103_0 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 1.389e-244 762.0
HKD1_k127_7107103_1 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 481.0
HKD1_k127_7107103_2 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 444.0
HKD1_k127_7107103_3 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000121 272.0
HKD1_k127_7107103_4 Type II/IV secretion system protein K02669 - - 0.00000009578 55.0
HKD1_k127_714035_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 5.317e-315 979.0
HKD1_k127_714035_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 459.0
HKD1_k127_714035_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000001461 223.0
HKD1_k127_714035_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000003022 216.0
HKD1_k127_714035_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000004013 80.0
HKD1_k127_7198927_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 0.0 1599.0
HKD1_k127_7198927_1 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 2.206e-301 959.0
HKD1_k127_7198927_10 ABC-type dipeptide oligopeptide nickel transport K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 377.0
HKD1_k127_7198927_11 ATPases associated with a variety of cellular activities K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 320.0
HKD1_k127_7198927_12 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 305.0
HKD1_k127_7198927_13 Oligopeptide dipeptide ABC transporter ATPase subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 301.0
HKD1_k127_7198927_14 Malate/L-lactate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003741 280.0
HKD1_k127_7198927_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006607 249.0
HKD1_k127_7198927_16 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001623 239.0
HKD1_k127_7198927_17 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000006083 224.0
HKD1_k127_7198927_18 EVE domain - - - 0.0000000000000000000000000000000000000000000000000003675 187.0
HKD1_k127_7198927_19 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000001251 197.0
HKD1_k127_7198927_2 Selenium-binding protein K17285 - - 2.235e-261 812.0
HKD1_k127_7198927_20 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000006053 168.0
HKD1_k127_7198927_21 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000003085 129.0
HKD1_k127_7198927_22 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000002383 118.0
HKD1_k127_7198927_23 Pfam:DUF385 - - - 0.0000000000000000000000001367 113.0
HKD1_k127_7198927_24 PFAM Transglycosylase associated protein - - - 0.0000000000000007214 83.0
HKD1_k127_7198927_25 Activator of Hsp90 ATPase 1 family protein - - - 0.000000000000008124 76.0
HKD1_k127_7198927_26 phosphatase activity K07025,K20866 - 3.1.3.10 0.00000000001202 72.0
HKD1_k127_7198927_27 AhpC/TSA family - - - 0.00000000004187 68.0
HKD1_k127_7198927_28 SNARE associated Golgi protein - - - 0.000000003417 59.0
HKD1_k127_7198927_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 9.338e-253 799.0
HKD1_k127_7198927_30 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000539 59.0
HKD1_k127_7198927_4 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 4.398e-250 799.0
HKD1_k127_7198927_5 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.87e-231 730.0
HKD1_k127_7198927_6 X-Pro dipeptidyl-peptidase domain protein K06978 - - 1.02e-212 690.0
HKD1_k127_7198927_7 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 431.0
HKD1_k127_7198927_8 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 443.0
HKD1_k127_7198927_9 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 409.0
HKD1_k127_7271241_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 2.443e-308 963.0
HKD1_k127_7271241_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 525.0
HKD1_k127_7271241_10 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 370.0
HKD1_k127_7271241_11 PFAM AMP-dependent synthetase and ligase K00666,K01897,K02182,K18661 - 6.2.1.3,6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 372.0
HKD1_k127_7271241_12 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 342.0
HKD1_k127_7271241_13 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 353.0
HKD1_k127_7271241_14 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 334.0
HKD1_k127_7271241_15 ABC transporter K02028,K02029,K09972,K10004 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 311.0
HKD1_k127_7271241_16 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 308.0
HKD1_k127_7271241_17 Required for the activity of the bacterial periplasmic transport system of putrescine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 318.0
HKD1_k127_7271241_18 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 313.0
HKD1_k127_7271241_19 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 286.0
HKD1_k127_7271241_2 Protein of unknown function (DUF1116) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 487.0
HKD1_k127_7271241_20 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 289.0
HKD1_k127_7271241_21 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000189 286.0
HKD1_k127_7271241_22 EamA-like transporter family K15268 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008164 260.0
HKD1_k127_7271241_23 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001298 272.0
HKD1_k127_7271241_24 extracellular solute-binding protein, family 1 K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001111 262.0
HKD1_k127_7271241_25 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001273 248.0
HKD1_k127_7271241_26 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000004787 247.0
HKD1_k127_7271241_27 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001085 250.0
HKD1_k127_7271241_28 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000001383 247.0
HKD1_k127_7271241_29 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000007332 233.0
HKD1_k127_7271241_3 Acetyl-CoA acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 475.0
HKD1_k127_7271241_30 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000001035 224.0
HKD1_k127_7271241_31 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000002678 235.0
HKD1_k127_7271241_32 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000005421 220.0
HKD1_k127_7271241_33 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000005991 237.0
HKD1_k127_7271241_34 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000005607 206.0
HKD1_k127_7271241_35 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000007061 201.0
HKD1_k127_7271241_36 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000004915 205.0
HKD1_k127_7271241_37 dehydratase - - - 0.00000000000000000000000000000000000000000000000000007005 199.0
HKD1_k127_7271241_38 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000003754 204.0
HKD1_k127_7271241_39 Protein of unknown function, DUF - - - 0.00000000000000000000000000000000000000757 147.0
HKD1_k127_7271241_4 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 501.0
HKD1_k127_7271241_40 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000000000000000002972 141.0
HKD1_k127_7271241_41 Transcription regulator K03718 - - 0.00000000000000000000000000000001496 134.0
HKD1_k127_7271241_42 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000003531 131.0
HKD1_k127_7271241_43 Cytochrome c K17222 - - 0.000000000000000000000000002134 118.0
HKD1_k127_7271241_44 helix_turn_helix, Arsenical Resistance Operon Repressor K03892,K21903 - - 0.00000000000000000000000001362 123.0
HKD1_k127_7271241_45 Beta-lactamase superfamily domain - - - 0.0000000000000000008024 97.0
HKD1_k127_7271241_46 Universal stress protein family - - - 0.000000000000000004147 95.0
HKD1_k127_7271241_47 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.000000000000004291 89.0
HKD1_k127_7271241_48 Belongs to the bacterial solute-binding protein 3 family K02424 - - 0.00000000000219 78.0
HKD1_k127_7271241_49 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000002084 61.0
HKD1_k127_7271241_5 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 419.0
HKD1_k127_7271241_6 Belongs to the ABC transporter superfamily K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 394.0
HKD1_k127_7271241_7 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 394.0
HKD1_k127_7271241_8 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 374.0
HKD1_k127_7271241_9 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00822,K00833 - 2.6.1.18,2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 394.0
HKD1_k127_7295020_0 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 581.0
HKD1_k127_7295020_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 417.0
HKD1_k127_7295020_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 383.0
HKD1_k127_7295020_3 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001765 284.0
HKD1_k127_7295020_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000002155 277.0
HKD1_k127_7365933_0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 430.0
HKD1_k127_7365933_1 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 394.0
HKD1_k127_7365933_10 Belongs to the 'phage' integrase family - - - 0.0001147 45.0
HKD1_k127_7365933_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001308 269.0
HKD1_k127_7365933_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000411 261.0
HKD1_k127_7365933_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000003647 243.0
HKD1_k127_7365933_5 Lysin motif - - - 0.00000000000000000000000000000000000004428 156.0
HKD1_k127_7365933_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000007355 123.0
HKD1_k127_7365933_7 Regulatory protein - - - 0.0000000000000000000000004339 109.0
HKD1_k127_7365933_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000001159 106.0
HKD1_k127_7365933_9 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000004161 74.0
HKD1_k127_7475145_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 587.0
HKD1_k127_7475145_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833,K03851,K12256,K15372 - 2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 475.0
HKD1_k127_7475145_10 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000004653 238.0
HKD1_k127_7475145_11 O-acyltransferase activity K00661 - 2.3.1.79 0.00000000000000000000000000000000000000000000000000000000000000009783 233.0
HKD1_k127_7475145_12 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000005856 217.0
HKD1_k127_7475145_13 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000008619 225.0
HKD1_k127_7475145_14 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000001109 188.0
HKD1_k127_7475145_15 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000001169 165.0
HKD1_k127_7475145_16 lysyltransferase activity - - - 0.0000000000000000000000000000000000001159 154.0
HKD1_k127_7475145_17 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000001163 113.0
HKD1_k127_7475145_18 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000003872 106.0
HKD1_k127_7475145_19 manganese ion transmembrane transporter activity - - - 0.00000000000000002 98.0
HKD1_k127_7475145_2 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 400.0
HKD1_k127_7475145_21 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000001045 88.0
HKD1_k127_7475145_3 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 386.0
HKD1_k127_7475145_4 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 370.0
HKD1_k127_7475145_5 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 355.0
HKD1_k127_7475145_6 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005507 273.0
HKD1_k127_7475145_7 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006608 269.0
HKD1_k127_7475145_8 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001447 243.0
HKD1_k127_7475145_9 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000005676 259.0
HKD1_k127_77642_0 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 404.0
HKD1_k127_77642_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 393.0
HKD1_k127_77642_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000005002 203.0
HKD1_k127_77642_3 ABC-type polar amino acid transport system ATPase component K09972 - - 0.0000000000000000000000000000000000005023 145.0
HKD1_k127_77642_4 - - - - 0.000000000000000000000000000000000003312 152.0
HKD1_k127_77642_5 - - - - 0.0000000000000000000000000000000004169 136.0
HKD1_k127_77642_6 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000007171 129.0
HKD1_k127_77642_7 - - - - 0.00000000000000000000000000007125 121.0
HKD1_k127_77642_8 ABC-type polar amino acid transport system ATPase component K02028,K09972 - 3.6.3.21 0.00000000000000001318 94.0
HKD1_k127_7827106_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 302.0
HKD1_k127_7827106_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001027 283.0
HKD1_k127_7827106_2 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000001415 180.0
HKD1_k127_7827106_3 amidohydrolase K07045 - - 0.000000000000000000000000000000000000008365 158.0
HKD1_k127_7827106_4 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000001929 146.0
HKD1_k127_7827106_5 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000001202 151.0
HKD1_k127_7827106_6 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000009465 135.0
HKD1_k127_7827106_7 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000004086 136.0
HKD1_k127_7827106_8 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000002455 93.0
HKD1_k127_7827106_9 TonB C terminal K03832 - - 0.000000000003151 78.0
HKD1_k127_799814_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 3.133e-286 893.0
HKD1_k127_799814_1 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006539 274.0
HKD1_k127_830983_0 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 499.0
HKD1_k127_830983_1 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 395.0
HKD1_k127_830983_2 ABC-type polysaccharide polyol phosphate export systems permease component K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 358.0
HKD1_k127_830983_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000846 302.0
HKD1_k127_830983_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006898 241.0
HKD1_k127_830983_5 - - - - 0.0000000000000000003389 103.0
HKD1_k127_830983_6 - - - - 0.00000000001485 78.0
HKD1_k127_830983_7 Sulfotransferase family, cytosolic, 2B, member K01015 GO:0000103,GO:0003674,GO:0003676,GO:0003824,GO:0004027,GO:0005488,GO:0005496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008285,GO:0008289,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015485,GO:0016125,GO:0016740,GO:0016782,GO:0019637,GO:0019693,GO:0030856,GO:0030858,GO:0032934,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0036094,GO:0042127,GO:0042562,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045595,GO:0045597,GO:0045604,GO:0045606,GO:0045682,GO:0045684,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050294,GO:0050427,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051239,GO:0055086,GO:0065007,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1901615,GO:1902652,GO:1990239,GO:2000026 2.8.2.2 0.000000005101 67.0
HKD1_k127_930659_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 604.0
HKD1_k127_930659_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 490.0
HKD1_k127_930659_10 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.0000000000000000000521 103.0
HKD1_k127_930659_2 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 299.0
HKD1_k127_930659_3 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001043 259.0
HKD1_k127_930659_4 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004209 272.0
HKD1_k127_930659_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 0.00000000000000000000000000000000000000000000000000000000000000000001032 239.0
HKD1_k127_930659_6 Amino-transferase class IV - - - 0.0000000000000000000000000000000000000000000000000000000000000000002211 240.0
HKD1_k127_930659_7 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000001638 213.0
HKD1_k127_930659_8 - - - - 0.0000000000000000000000000000000000000000000000001328 189.0
HKD1_k127_930659_9 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000001209 185.0
HKD1_k127_944565_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 9.203e-212 672.0
HKD1_k127_944565_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 2.624e-197 631.0
HKD1_k127_944565_10 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 392.0
HKD1_k127_944565_100 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000006605 83.0
HKD1_k127_944565_101 Ribosomal protein L30 K02907 - - 0.0000000000007879 72.0
HKD1_k127_944565_102 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000003369 68.0
HKD1_k127_944565_103 PFAM Bile acid sodium symporter K03453 - - 0.000000000008261 77.0
HKD1_k127_944565_104 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000001635 70.0
HKD1_k127_944565_105 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.00000000357 66.0
HKD1_k127_944565_106 - - - - 0.00000002759 59.0
HKD1_k127_944565_107 Putative zinc-finger - - - 0.0000001747 63.0
HKD1_k127_944565_108 Helix-hairpin-helix motif K02237 - - 0.0000009108 60.0
HKD1_k127_944565_109 PFAM Cupin 2 conserved barrel domain protein - - - 0.000001773 55.0
HKD1_k127_944565_11 oxidoreductase activity, acting on CH-OH group of donors K00034 - 1.1.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 368.0
HKD1_k127_944565_110 Sulfatase K01133 - 3.1.6.6 0.000004449 53.0
HKD1_k127_944565_112 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0002511 49.0
HKD1_k127_944565_113 Helix-hairpin-helix motif - - - 0.0006878 52.0
HKD1_k127_944565_12 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 389.0
HKD1_k127_944565_13 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 365.0
HKD1_k127_944565_14 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 350.0
HKD1_k127_944565_15 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 368.0
HKD1_k127_944565_16 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 338.0
HKD1_k127_944565_17 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 332.0
HKD1_k127_944565_18 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 325.0
HKD1_k127_944565_19 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 327.0
HKD1_k127_944565_2 Rubrerythrin K22405 - 1.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007975 569.0
HKD1_k127_944565_20 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 321.0
HKD1_k127_944565_21 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 307.0
HKD1_k127_944565_22 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 322.0
HKD1_k127_944565_23 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 296.0
HKD1_k127_944565_24 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 292.0
HKD1_k127_944565_25 Squalene/phytoene synthase K00801,K02291,K10208 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 296.0
HKD1_k127_944565_26 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001057 302.0
HKD1_k127_944565_27 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003983 299.0
HKD1_k127_944565_28 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005006 288.0
HKD1_k127_944565_29 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004851 274.0
HKD1_k127_944565_3 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 564.0
HKD1_k127_944565_30 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006632 280.0
HKD1_k127_944565_31 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005429 292.0
HKD1_k127_944565_32 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000001118 266.0
HKD1_k127_944565_33 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002549 267.0
HKD1_k127_944565_34 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000841 271.0
HKD1_k127_944565_35 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001105 262.0
HKD1_k127_944565_36 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001229 264.0
HKD1_k127_944565_37 Competence protein ComEC K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001588 280.0
HKD1_k127_944565_38 protein tyrosine kinase activity K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006375 270.0
HKD1_k127_944565_39 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000002704 251.0
HKD1_k127_944565_4 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 530.0
HKD1_k127_944565_40 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001964 254.0
HKD1_k127_944565_41 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004694 248.0
HKD1_k127_944565_42 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.0000000000000000000000000000000000000000000000000000000000000000000004795 244.0
HKD1_k127_944565_43 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001056 261.0
HKD1_k127_944565_44 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000004227 258.0
HKD1_k127_944565_45 B3 4 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000007321 237.0
HKD1_k127_944565_46 PFAM Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000005955 236.0
HKD1_k127_944565_47 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000158 243.0
HKD1_k127_944565_48 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000003128 222.0
HKD1_k127_944565_49 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001553 222.0
HKD1_k127_944565_5 Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 522.0
HKD1_k127_944565_50 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000000000000000000000000000000000000000000000000000000002422 235.0
HKD1_k127_944565_51 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000000000003013 218.0
HKD1_k127_944565_52 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000003188 214.0
HKD1_k127_944565_53 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000004427 213.0
HKD1_k127_944565_54 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000000000000000000000000000000000000000000000000003072 220.0
HKD1_k127_944565_55 Cytochrome oxidase assembly protein K02259,K03110 - - 0.00000000000000000000000000000000000000000000000000000000006187 232.0
HKD1_k127_944565_56 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000008494 212.0
HKD1_k127_944565_57 Proto-chlorophyllide reductase 57 kD subunit - - - 0.000000000000000000000000000000000000000000000000000000001445 219.0
HKD1_k127_944565_58 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000001134 194.0
HKD1_k127_944565_59 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000002145 191.0
HKD1_k127_944565_6 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 522.0
HKD1_k127_944565_60 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000006367 194.0
HKD1_k127_944565_61 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001042 189.0
HKD1_k127_944565_62 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000005003 189.0
HKD1_k127_944565_63 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000009372 180.0
HKD1_k127_944565_64 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000003137 196.0
HKD1_k127_944565_65 Forms part of the polypeptide exit tunnel K02926,K16193 GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000004571 189.0
HKD1_k127_944565_66 Redoxin domain protein - - - 0.000000000000000000000000000000000000000000001385 171.0
HKD1_k127_944565_67 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000175 168.0
HKD1_k127_944565_68 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000007223 169.0
HKD1_k127_944565_69 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000001169 159.0
HKD1_k127_944565_7 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 479.0
HKD1_k127_944565_70 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000003084 153.0
HKD1_k127_944565_71 high-affinity Fe2 Pb2 permease K07243 - - 0.00000000000000000000000000000000000001095 155.0
HKD1_k127_944565_72 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000005553 164.0
HKD1_k127_944565_73 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000002507 146.0
HKD1_k127_944565_74 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000007298 151.0
HKD1_k127_944565_75 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000000000000000000000009163 142.0
HKD1_k127_944565_76 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000001848 139.0
HKD1_k127_944565_77 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000192 145.0
HKD1_k127_944565_78 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000193 139.0
HKD1_k127_944565_79 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000002014 134.0
HKD1_k127_944565_8 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 480.0
HKD1_k127_944565_80 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000002043 141.0
HKD1_k127_944565_81 endoribonuclease activity K03628,K15125 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000212 131.0
HKD1_k127_944565_82 Ribosomal protein L22p/L17e K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000002089 128.0
HKD1_k127_944565_83 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000003707 132.0
HKD1_k127_944565_84 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000091 134.0
HKD1_k127_944565_85 Bacterial PH domain - - - 0.000000000000000000000000000002564 127.0
HKD1_k127_944565_86 (Barnase) inhibitor - - - 0.000000000000000000000000000004044 125.0
HKD1_k127_944565_87 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000001467 134.0
HKD1_k127_944565_88 Helix-hairpin-helix motif - - - 0.00000000000000000000000000002333 133.0
HKD1_k127_944565_89 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000123 111.0
HKD1_k127_944565_9 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 451.0
HKD1_k127_944565_90 Cytochrome c K02305 - - 0.0000000000000000000000002961 123.0
HKD1_k127_944565_91 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001238 105.0
HKD1_k127_944565_92 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000005374 110.0
HKD1_k127_944565_93 Hep Hag repeat protein K21449 - - 0.0000000000000000000000667 109.0
HKD1_k127_944565_94 Cupredoxin-like domain - - - 0.00000000000000000000006937 102.0
HKD1_k127_944565_95 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000001482 102.0
HKD1_k127_944565_96 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000002618 93.0
HKD1_k127_944565_97 Protein of unknown function (DUF983) - - - 0.000000000000000006831 88.0
HKD1_k127_944565_98 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001413 79.0
HKD1_k127_944565_99 - - - - 0.00000000000001098 83.0