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Overview

ID MAG01714
Name HKD1_bin.29
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA9159
Genus DASRZP01
Species
Assembly information
Completeness (%) 79.42
Contamination (%) 3.28
GC content (%) 52.0
N50 (bp) 10,967
Genome size (bp) 2,149,888

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2043

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1045536_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1257.0
HKD1_k127_1045536_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1123.0
HKD1_k127_1045536_10 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 354.0
HKD1_k127_1045536_11 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 341.0
HKD1_k127_1045536_12 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 357.0
HKD1_k127_1045536_13 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 326.0
HKD1_k127_1045536_15 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 325.0
HKD1_k127_1045536_16 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 319.0
HKD1_k127_1045536_17 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 292.0
HKD1_k127_1045536_18 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000855 261.0
HKD1_k127_1045536_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000002638 246.0
HKD1_k127_1045536_2 Beta-lactamase - - - 9.755e-283 890.0
HKD1_k127_1045536_20 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000002866 242.0
HKD1_k127_1045536_21 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003313 239.0
HKD1_k127_1045536_22 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000004794 220.0
HKD1_k127_1045536_23 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000002074 192.0
HKD1_k127_1045536_24 Belongs to the small heat shock protein (HSP20) family K06335,K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.00000000000000000000000000000000000000000000009913 175.0
HKD1_k127_1045536_25 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000001335 177.0
HKD1_k127_1045536_26 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000834 162.0
HKD1_k127_1045536_27 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000693 132.0
HKD1_k127_1045536_29 - - - - 0.000000000000000000000001072 108.0
HKD1_k127_1045536_3 Predicted permease K07089 - - 1.982e-239 755.0
HKD1_k127_1045536_30 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000001204 79.0
HKD1_k127_1045536_31 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.000000000001216 80.0
HKD1_k127_1045536_33 peptidyl-tyrosine sulfation - - - 0.000004993 55.0
HKD1_k127_1045536_34 peptidylprolyl isomerase K07533 - 5.2.1.8 0.0001715 53.0
HKD1_k127_1045536_4 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 536.0
HKD1_k127_1045536_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 515.0
HKD1_k127_1045536_6 SMART Elongator protein 3 MiaB NifB K22226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 490.0
HKD1_k127_1045536_7 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 483.0
HKD1_k127_1045536_8 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 473.0
HKD1_k127_1045536_9 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 408.0
HKD1_k127_1047214_0 dioxygenase K15777 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 384.0
HKD1_k127_1047214_1 Flavodoxin-like fold K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001704 269.0
HKD1_k127_1047214_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000002962 258.0
HKD1_k127_1047214_3 ATPase (AAA superfamily) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000002169 237.0
HKD1_k127_1047214_5 PFAM response regulator receiver K07657,K07658 - - 0.000000000000000000000000002058 115.0
HKD1_k127_1047214_6 Cytochrome c - - - 0.0000002421 59.0
HKD1_k127_1047214_7 Outer membrane lipoprotein K05807,K08309 - - 0.00001714 57.0
HKD1_k127_1047285_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 3.339e-203 638.0
HKD1_k127_1047285_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 332.0
HKD1_k127_1047285_2 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001467 256.0
HKD1_k127_1047285_3 ribonuclease III activity K03685,K07053 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3,3.1.3.97 0.00000000000000000000000000000000000000000000000000001139 199.0
HKD1_k127_1047285_4 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000005315 168.0
HKD1_k127_1047285_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000007038 126.0
HKD1_k127_1047358_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 3.441e-215 703.0
HKD1_k127_1047358_1 Domain of unknown function (DUF4070) - - - 6.652e-211 667.0
HKD1_k127_1047358_10 - - - - 0.0000002494 57.0
HKD1_k127_1047358_11 PFAM Lytic transglycosylase catalytic - - - 0.000002287 57.0
HKD1_k127_1047358_2 PLD-like domain K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 551.0
HKD1_k127_1047358_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000002138 211.0
HKD1_k127_1047358_4 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000005002 150.0
HKD1_k127_1047358_5 translation release factor activity - - - 0.00000000000000000000000000000000000006242 147.0
HKD1_k127_1047358_6 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000000000000000000001198 140.0
HKD1_k127_1047358_7 Transglycosylase associated protein - - - 0.000000000000000000000000000000003648 130.0
HKD1_k127_1047358_8 Restriction endonuclease XhoI K01155 - 3.1.21.4 0.000000000000005486 76.0
HKD1_k127_1047358_9 PFAM Cytochrome bd ubiquinol oxidase, subunit I K00425 - 1.10.3.14 0.00000000003473 63.0
HKD1_k127_1072610_0 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 353.0
HKD1_k127_1072610_2 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 323.0
HKD1_k127_1072610_3 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000004226 234.0
HKD1_k127_1072610_4 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000009948 120.0
HKD1_k127_1072610_5 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000001744 100.0
HKD1_k127_1072610_6 - - - - 0.000000000000007574 79.0
HKD1_k127_1072610_7 protein conserved in bacteria K09796 - - 0.0000000005178 66.0
HKD1_k127_1082915_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 554.0
HKD1_k127_1082915_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 517.0
HKD1_k127_1082915_2 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 414.0
HKD1_k127_1082915_3 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000973 275.0
HKD1_k127_1082915_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0050136,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000002717 131.0
HKD1_k127_1082915_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000979 117.0
HKD1_k127_1082915_7 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity K03182 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 0.0000000000000000000000001856 106.0
HKD1_k127_1101979_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 546.0
HKD1_k127_1101979_1 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 424.0
HKD1_k127_1101979_2 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 398.0
HKD1_k127_1101979_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 387.0
HKD1_k127_1101979_4 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000001595 238.0
HKD1_k127_1101979_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000002284 164.0
HKD1_k127_1101979_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.000000000000000000000000000000008466 137.0
HKD1_k127_1154660_0 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 479.0
HKD1_k127_1154660_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003307 282.0
HKD1_k127_1154660_2 PFAM HPP family K07168 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003933 246.0
HKD1_k127_1154660_3 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000003263 188.0
HKD1_k127_1154660_4 Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000000000000000000005431 182.0
HKD1_k127_1154660_5 GDP-mannose mannosyl hydrolase activity - - - 0.000000000000000000000001486 104.0
HKD1_k127_1154660_6 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.00000000000000000000005354 102.0
HKD1_k127_1154660_7 belongs to the sigma-70 factor family - - - 0.00000000007673 72.0
HKD1_k127_1160702_0 Ftsk_gamma K03466 - - 1.565e-213 683.0
HKD1_k127_1160702_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 597.0
HKD1_k127_1160702_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 505.0
HKD1_k127_1160702_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 374.0
HKD1_k127_1160702_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 362.0
HKD1_k127_1160702_5 DoxX K15977 - - 0.00000000000000000000000000000000000000000000008899 171.0
HKD1_k127_1160702_6 His Kinase A (phosphoacceptor) domain - - - 0.000004217 51.0
HKD1_k127_1180492_0 Protein of unknown function, DUF255 K06888 - - 7.895e-241 762.0
HKD1_k127_1180492_1 PFAM natural resistance-associated macrophage protein K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 529.0
HKD1_k127_1180492_10 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K07025 - - 0.00000000000000000000000000000000000000000000000002715 185.0
HKD1_k127_1180492_12 Type III restriction enzyme res subunit K01156 - 3.1.21.5 0.0000000000000000000000000000000000004065 143.0
HKD1_k127_1180492_13 Cytochrome P460 - - - 0.000000000000000000000000000000000009091 143.0
HKD1_k127_1180492_14 electron transfer activity K00428 - 1.11.1.5 0.00000000000000000000000002499 112.0
HKD1_k127_1180492_15 PFAM Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.0000000000000000000000001012 120.0
HKD1_k127_1180492_16 Protein of unknown function (DUF433) - - - 0.0000000000006593 71.0
HKD1_k127_1180492_17 Protein of unknown function (DUF2283) - - - 0.00000000001197 68.0
HKD1_k127_1180492_18 Acyl-coenzyme A thioesterase K01068 GO:0003674,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007031,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010559,GO:0010561,GO:0010605,GO:0016042,GO:0016043,GO:0016054,GO:0016289,GO:0016290,GO:0016559,GO:0016787,GO:0016788,GO:0016790,GO:0019222,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031907,GO:0031974,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045223,GO:0045225,GO:0046395,GO:0046483,GO:0047617,GO:0048285,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051246,GO:0051248,GO:0052815,GO:0055086,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0072521,GO:0080090,GO:1901135,GO:1901360,GO:1901564,GO:1901575,GO:1903018,GO:1903019,GO:2000112,GO:2000113 3.1.2.2 0.00005215 55.0
HKD1_k127_1180492_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 440.0
HKD1_k127_1180492_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 395.0
HKD1_k127_1180492_4 COG1194 A G-specific DNA glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 335.0
HKD1_k127_1180492_5 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 328.0
HKD1_k127_1180492_6 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 308.0
HKD1_k127_1180492_7 DJ-1/PfpI family K03152,K05520,K05687 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000006634 249.0
HKD1_k127_1180492_8 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001209 235.0
HKD1_k127_1180492_9 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000126 198.0
HKD1_k127_1185208_0 Polysaccharide biosynthesis protein K03328 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 362.0
HKD1_k127_1185208_1 cyclopropane-fatty-acyl-phospholipid synthase K00574,K15256,K15257 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 298.0
HKD1_k127_1185208_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 302.0
HKD1_k127_1185208_3 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 301.0
HKD1_k127_1185208_4 methyltransferase activity K00563,K02169 - 2.1.1.187,2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000006143 248.0
HKD1_k127_1185208_5 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000001106 204.0
HKD1_k127_1185208_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000576 207.0
HKD1_k127_1215001_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1107.0
HKD1_k127_1215001_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 287.0
HKD1_k127_1215001_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000002946 131.0
HKD1_k127_1215001_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000005895 87.0
HKD1_k127_1229740_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 507.0
HKD1_k127_1229740_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 482.0
HKD1_k127_1229740_2 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 386.0
HKD1_k127_1229740_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 336.0
HKD1_k127_1229740_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 314.0
HKD1_k127_1229740_5 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000006798 268.0
HKD1_k127_1258602_0 Epimerase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 315.0
HKD1_k127_1258602_1 Thrombospondin type 1 repeats - - - 0.00000000000000000000000000000000000000000000000000000000000002522 228.0
HKD1_k127_1258602_2 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000002206 97.0
HKD1_k127_1258602_5 Recombinase - - - 0.00003017 46.0
HKD1_k127_1258602_6 - - - - 0.0003116 44.0
HKD1_k127_1287516_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.035e-240 782.0
HKD1_k127_1287516_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 486.0
HKD1_k127_1287516_10 Tetratricopeptide repeat K06665 GO:0000122,GO:0000228,GO:0000785,GO:0000790,GO:0000988,GO:0000989,GO:0001076,GO:0001190,GO:0001191,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0006139,GO:0006323,GO:0006325,GO:0006333,GO:0006338,GO:0006342,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016458,GO:0016584,GO:0017053,GO:0018130,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0022607,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031497,GO:0031974,GO:0031981,GO:0032774,GO:0032879,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0034728,GO:0035950,GO:0035952,GO:0035953,GO:0035955,GO:0040029,GO:0042304,GO:0042826,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0045814,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046890,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0060255,GO:0062012,GO:0065007,GO:0070013,GO:0071103,GO:0071704,GO:0071824,GO:0071840,GO:0072364,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090088,GO:0090089,GO:0090304,GO:0090568,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2000531,GO:2000877,GO:2000879,GO:2001020,GO:2001141 - 0.000000001333 68.0
HKD1_k127_1287516_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 427.0
HKD1_k127_1287516_3 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 383.0
HKD1_k127_1287516_4 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 352.0
HKD1_k127_1287516_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000002075 261.0
HKD1_k127_1287516_6 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000001538 225.0
HKD1_k127_1287516_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000000005645 205.0
HKD1_k127_1287516_8 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000002014 134.0
HKD1_k127_1287516_9 CAAX protease self-immunity K07052 - - 0.000000000001788 74.0
HKD1_k127_1300362_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 563.0
HKD1_k127_1300362_1 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 484.0
HKD1_k127_1300362_10 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000001901 98.0
HKD1_k127_1300362_11 STAS domain K04749 - - 0.000000000000000000002276 97.0
HKD1_k127_1300362_12 - - - - 0.00000000000000000004462 90.0
HKD1_k127_1300362_13 PFAM Mammalian cell entry related K02067 - - 0.000000000000000004147 95.0
HKD1_k127_1300362_14 - - - - 0.0000000000000000232 87.0
HKD1_k127_1300362_15 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0004426 50.0
HKD1_k127_1300362_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 473.0
HKD1_k127_1300362_3 PHB de-polymerase C-terminus K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 449.0
HKD1_k127_1300362_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 335.0
HKD1_k127_1300362_5 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 323.0
HKD1_k127_1300362_6 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 287.0
HKD1_k127_1300362_7 Stage II sporulation protein E (SpoIIE) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006576 256.0
HKD1_k127_1300362_8 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000009787 192.0
HKD1_k127_1300362_9 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000000000000000000000006533 117.0
HKD1_k127_1330159_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.174e-293 910.0
HKD1_k127_1330159_1 CAAX prenyl protease N-terminal, five membrane helices - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 493.0
HKD1_k127_1330159_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 354.0
HKD1_k127_1330159_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 340.0
HKD1_k127_1330159_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 316.0
HKD1_k127_1330159_5 glyoxalase III activity K13653 - - 0.000000000000000000000000000000000000000000000000000000000000000000002643 239.0
HKD1_k127_1330159_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000003359 241.0
HKD1_k127_1330159_7 copG family - - - 0.000000000000000000000000522 106.0
HKD1_k127_1330159_8 Cell wall hydrolase autolysin - - - 0.00000000000003917 83.0
HKD1_k127_1330159_9 PFAM Sporulation and spore germination - - - 0.00000000273 65.0
HKD1_k127_1330885_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1081.0
HKD1_k127_1330885_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 8.933e-321 986.0
HKD1_k127_1330885_10 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000005109 171.0
HKD1_k127_1330885_11 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000007012 113.0
HKD1_k127_1330885_2 FMN binding - - - 9.538e-276 854.0
HKD1_k127_1330885_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.523e-263 823.0
HKD1_k127_1330885_4 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 428.0
HKD1_k127_1330885_5 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 424.0
HKD1_k127_1330885_6 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 408.0
HKD1_k127_1330885_7 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 385.0
HKD1_k127_1330885_8 PFAM response regulator receiver K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 292.0
HKD1_k127_1330885_9 PFAM Glutamine amidotransferase, class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 299.0
HKD1_k127_1341303_0 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 431.0
HKD1_k127_1341303_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 396.0
HKD1_k127_1341303_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 382.0
HKD1_k127_1341303_3 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 314.0
HKD1_k127_1341303_4 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000000000000000000000000001277 197.0
HKD1_k127_1341303_5 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.000000000000000000000000000000000000000000000000009006 190.0
HKD1_k127_1341303_6 protein homooligomerization - - - 0.000000812 53.0
HKD1_k127_1363724_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2111.0
HKD1_k127_1363724_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.288e-254 797.0
HKD1_k127_1363724_10 His Kinase A (phosphoacceptor) domain K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 308.0
HKD1_k127_1363724_11 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 313.0
HKD1_k127_1363724_12 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004151 280.0
HKD1_k127_1363724_13 Mo-molybdopterin cofactor metabolic process K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003809 262.0
HKD1_k127_1363724_14 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000004064 136.0
HKD1_k127_1363724_15 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000001425 108.0
HKD1_k127_1363724_16 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000002593 79.0
HKD1_k127_1363724_17 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000415 76.0
HKD1_k127_1363724_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 4.72e-222 696.0
HKD1_k127_1363724_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.85e-216 679.0
HKD1_k127_1363724_4 General secretory system II, protein E domain protein K02652 - - 4.414e-214 681.0
HKD1_k127_1363724_5 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008906 530.0
HKD1_k127_1363724_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 511.0
HKD1_k127_1363724_7 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 469.0
HKD1_k127_1363724_8 TrkA-N domain K03455,K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 366.0
HKD1_k127_1363724_9 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 355.0
HKD1_k127_1409803_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 524.0
HKD1_k127_1409803_1 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 316.0
HKD1_k127_1409803_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000006568 259.0
HKD1_k127_1409803_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000001141 232.0
HKD1_k127_1409803_4 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000002266 117.0
HKD1_k127_1409803_5 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000004577 64.0
HKD1_k127_1409803_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00006551 49.0
HKD1_k127_1508523_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 1.361e-264 829.0
HKD1_k127_1508523_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 2.058e-234 733.0
HKD1_k127_1508523_10 - - - - 0.00000000001206 74.0
HKD1_k127_1508523_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 602.0
HKD1_k127_1508523_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 439.0
HKD1_k127_1508523_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 304.0
HKD1_k127_1508523_5 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004591 228.0
HKD1_k127_1508523_6 4Fe-4S dicluster domain K00196 - - 0.0000000000000000000000000000000000000000000000002473 182.0
HKD1_k127_1508523_7 PhoQ Sensor - - - 0.000000000000000000000000000000007364 138.0
HKD1_k127_1508523_8 - - - - 0.0000000000000000000002012 101.0
HKD1_k127_1508523_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000001476 73.0
HKD1_k127_1562672_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 587.0
HKD1_k127_1562672_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 502.0
HKD1_k127_1562672_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 402.0
HKD1_k127_1562672_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 291.0
HKD1_k127_1562672_4 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000000000000254 181.0
HKD1_k127_1562672_5 Predicted RNA-binding protein - - - 0.00000000000002454 78.0
HKD1_k127_1610995_0 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 338.0
HKD1_k127_1610995_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 288.0
HKD1_k127_1610995_2 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009968 277.0
HKD1_k127_1610995_3 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000004127 227.0
HKD1_k127_1610995_4 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000002294 206.0
HKD1_k127_1610995_5 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000002117 198.0
HKD1_k127_1610995_8 diguanylate cyclase - - - 0.00000001942 56.0
HKD1_k127_1646755_0 Elongation factor G, domain IV K02355 - - 2.871e-311 968.0
HKD1_k127_1646755_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 8.494e-252 794.0
HKD1_k127_1646755_10 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000001495 196.0
HKD1_k127_1646755_11 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000004239 151.0
HKD1_k127_1646755_12 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000001474 116.0
HKD1_k127_1646755_13 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.000000000000000004976 89.0
HKD1_k127_1646755_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 8.51e-223 706.0
HKD1_k127_1646755_3 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 595.0
HKD1_k127_1646755_4 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 514.0
HKD1_k127_1646755_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 439.0
HKD1_k127_1646755_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 445.0
HKD1_k127_1646755_7 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 383.0
HKD1_k127_1646755_8 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001487 272.0
HKD1_k127_1646755_9 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002995 243.0
HKD1_k127_1650722_0 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000003457 181.0
HKD1_k127_1650722_1 AI-2E family transporter - - - 0.000000000000000000000000000000000132 146.0
HKD1_k127_1650722_2 Glycosyltransferase like family 2 - - - 0.000000000000000000002475 95.0
HKD1_k127_1650722_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000001537 89.0
HKD1_k127_1713162_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 523.0
HKD1_k127_1713162_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 438.0
HKD1_k127_1713162_2 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 393.0
HKD1_k127_1713162_3 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000024 241.0
HKD1_k127_1713162_4 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000001209 156.0
HKD1_k127_1713162_5 cheY-homologous receiver domain - - - 0.000000004702 67.0
HKD1_k127_172705_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 507.0
HKD1_k127_172705_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 489.0
HKD1_k127_172705_10 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000002231 124.0
HKD1_k127_172705_11 Ion channel K10716 - - 0.000000000000000000001839 96.0
HKD1_k127_172705_12 response regulator receiver K02658 - - 0.0000000000000000002976 100.0
HKD1_k127_172705_13 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000002174 88.0
HKD1_k127_172705_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 480.0
HKD1_k127_172705_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003359 275.0
HKD1_k127_172705_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000005008 243.0
HKD1_k127_172705_5 Polysaccharide deacetylase K11931 - - 0.00000000000000000000000000000000000000000000000000000000000000000001434 247.0
HKD1_k127_172705_6 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000000000000000001435 196.0
HKD1_k127_172705_7 AMP binding - - - 0.0000000000000000000000000000000000000000000368 165.0
HKD1_k127_172705_9 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000003042 132.0
HKD1_k127_1747761_0 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 529.0
HKD1_k127_1747761_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 518.0
HKD1_k127_1747761_2 Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000001055 182.0
HKD1_k127_1747761_3 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.00000000000000007996 91.0
HKD1_k127_1839158_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 8.607e-248 777.0
HKD1_k127_1839158_1 Sigma-54 interaction domain - - - 6.483e-217 685.0
HKD1_k127_1839158_10 Aminoacyl-tRNA editing domain K03976 - - 0.00000000000000000000000000000000000000000000000000000000000003502 218.0
HKD1_k127_1839158_11 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000002702 198.0
HKD1_k127_1839158_12 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000007164 196.0
HKD1_k127_1839158_13 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000005524 186.0
HKD1_k127_1839158_14 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000002238 171.0
HKD1_k127_1839158_15 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000007455 162.0
HKD1_k127_1839158_16 VanZ like family - - - 0.0000000000000000000000000000000000002622 148.0
HKD1_k127_1839158_17 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.00000000000000000000000001614 114.0
HKD1_k127_1839158_18 Cupin 2, conserved barrel domain protein - - - 0.00000008929 53.0
HKD1_k127_1839158_2 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22341 - 1.17.1.11,1.17.1.9 1.782e-198 631.0
HKD1_k127_1839158_3 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 549.0
HKD1_k127_1839158_4 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 500.0
HKD1_k127_1839158_5 pseudouridine synthase activity K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 422.0
HKD1_k127_1839158_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 332.0
HKD1_k127_1839158_7 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 312.0
HKD1_k127_1839158_8 LysM domain K01449,K19223 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000009882 246.0
HKD1_k127_1839158_9 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002051 238.0
HKD1_k127_1849140_0 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 615.0
HKD1_k127_1849140_1 phosphorelay signal transduction system K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 475.0
HKD1_k127_1849140_2 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 336.0
HKD1_k127_1849140_3 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 287.0
HKD1_k127_1849140_4 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000008549 206.0
HKD1_k127_1849140_5 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000000000000003002 171.0
HKD1_k127_1849140_6 hydrogenase 4 membrane K12140 - - 0.0000000000000000001671 92.0
HKD1_k127_1849140_7 - K07803 - - 0.00000000000005069 78.0
HKD1_k127_1849140_8 - - - - 0.00000000002381 70.0
HKD1_k127_18539_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 476.0
HKD1_k127_18539_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 331.0
HKD1_k127_18539_10 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000000001882 92.0
HKD1_k127_18539_2 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 295.0
HKD1_k127_18539_3 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 283.0
HKD1_k127_18539_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002716 277.0
HKD1_k127_18539_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000004904 260.0
HKD1_k127_18539_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000002179 228.0
HKD1_k127_18539_7 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000004656 224.0
HKD1_k127_18539_8 Transcriptional regulator - - - 0.00000000000000000000000000000000000003105 151.0
HKD1_k127_18539_9 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000003812 141.0
HKD1_k127_188550_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.781e-292 909.0
HKD1_k127_188550_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 3.451e-242 771.0
HKD1_k127_188550_10 protein secretion K03116 - - 0.00000000000005328 73.0
HKD1_k127_188550_12 sulfur relay protein TusB DsrH K07237 - - 0.00001125 51.0
HKD1_k127_188550_13 PFAM DsrE family protein K06039,K07235 - - 0.0000156 51.0
HKD1_k127_188550_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 525.0
HKD1_k127_188550_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 443.0
HKD1_k127_188550_4 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000006355 244.0
HKD1_k127_188550_5 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000005184 208.0
HKD1_k127_188550_6 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.00000000000000000000002128 104.0
HKD1_k127_188550_7 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000003628 95.0
HKD1_k127_188550_8 YtxH-like protein - - - 0.00000000000000000004118 98.0
HKD1_k127_188550_9 - - - - 0.0000000000000001785 82.0
HKD1_k127_1974063_0 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000007741 244.0
HKD1_k127_1974063_1 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000006545 128.0
HKD1_k127_1974063_3 - - - - 0.0000000000000000000000001922 109.0
HKD1_k127_1974063_4 - - - - 0.0000000001231 67.0
HKD1_k127_1974063_5 DnaJ and TPR domain protein K09523 - - 0.000000003092 66.0
HKD1_k127_2037986_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 379.0
HKD1_k127_2037986_1 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000000000721 160.0
HKD1_k127_2037986_2 Protein of unknown function (DUF2867) - - - 0.00000000001744 64.0
HKD1_k127_2037986_4 - - - - 0.00000007661 55.0
HKD1_k127_2041820_0 Elongator protein 3, MiaB family, Radical SAM K04034 - 1.21.98.3 4.331e-214 673.0
HKD1_k127_2041820_1 glycosyl transferase family 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 423.0
HKD1_k127_2041820_2 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 396.0
HKD1_k127_2041820_3 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006456 276.0
HKD1_k127_2041820_4 spore germination - - - 0.00000000000000000000000000000000001194 139.0
HKD1_k127_2041820_5 Protein of unknown function DUF116 - - - 0.000000000000000000006835 94.0
HKD1_k127_2041820_6 EamA-like transporter family - - - 0.00000000000000002198 87.0
HKD1_k127_2041820_7 phosphorylase K01243 - 3.2.2.9 0.00000004982 63.0
HKD1_k127_20503_0 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 364.0
HKD1_k127_20503_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 340.0
HKD1_k127_20503_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 319.0
HKD1_k127_20503_3 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000001055 216.0
HKD1_k127_20503_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000003318 212.0
HKD1_k127_2055345_0 FecR protein - - - 0.0 1199.0
HKD1_k127_2055345_1 CHASE2 K01768 - 4.6.1.1 7.387e-245 777.0
HKD1_k127_2055345_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 608.0
HKD1_k127_2055345_3 CoA binding domain K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 503.0
HKD1_k127_2055345_4 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 449.0
HKD1_k127_2055345_5 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 449.0
HKD1_k127_2055345_6 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 405.0
HKD1_k127_2055345_7 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 344.0
HKD1_k127_2055345_8 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004165 287.0
HKD1_k127_2055345_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000001878 93.0
HKD1_k127_2072895_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 5.216e-217 683.0
HKD1_k127_2072895_1 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 468.0
HKD1_k127_2072895_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000547 434.0
HKD1_k127_2072895_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 354.0
HKD1_k127_2072895_4 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 329.0
HKD1_k127_2072895_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001282 268.0
HKD1_k127_2072895_6 Tautomerase enzyme K01821 - 5.3.2.6 0.000000000000000000000000005278 112.0
HKD1_k127_2072895_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000592 63.0
HKD1_k127_2096526_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 5.277e-269 854.0
HKD1_k127_2096526_1 DNA polymerase K02347 - - 6.18e-226 714.0
HKD1_k127_2096526_10 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000168 209.0
HKD1_k127_2096526_11 mRNA catabolic process K06950 - - 0.00000000000000000000000000000000000000000000000000000001564 202.0
HKD1_k127_2096526_12 - - - - 0.000000000000000000000000000000000000000000000000000000169 205.0
HKD1_k127_2096526_13 Glutaredoxin K03676 - - 0.00000000001016 66.0
HKD1_k127_2096526_14 - - - - 0.00000006543 57.0
HKD1_k127_2096526_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.135e-203 640.0
HKD1_k127_2096526_3 Fructose-bisphosphate aldolase class-II - - - 4.196e-201 634.0
HKD1_k127_2096526_4 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 386.0
HKD1_k127_2096526_5 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 366.0
HKD1_k127_2096526_6 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 365.0
HKD1_k127_2096526_7 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 286.0
HKD1_k127_2096526_8 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001086 297.0
HKD1_k127_2096526_9 Methyltransferase K15256 - - 0.0000000000000000000000000000000000000000000000000000000000003082 219.0
HKD1_k127_2116894_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 5.696e-248 782.0
HKD1_k127_2116894_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 7.858e-230 728.0
HKD1_k127_2116894_2 glycolate transport K14393 - - 2.404e-217 682.0
HKD1_k127_2116894_3 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 456.0
HKD1_k127_2116894_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000002508 153.0
HKD1_k127_2116894_5 Protein of unknown function, DUF485 - - - 0.000000000000000000000000002482 114.0
HKD1_k127_2116894_6 PFAM sigma-54 factor interaction domain-containing protein, helix-turn-helix Fis-type K21405 - - 0.000000008684 56.0
HKD1_k127_2151222_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 437.0
HKD1_k127_2151222_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 342.0
HKD1_k127_2151222_2 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 328.0
HKD1_k127_2151222_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 322.0
HKD1_k127_2151222_4 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000008104 233.0
HKD1_k127_2151222_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000004156 201.0
HKD1_k127_2151222_6 PFAM Cytochrome c, class III, conserved region K03686,K04082,K05516 - - 0.0000000003503 67.0
HKD1_k127_2175840_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.022e-244 766.0
HKD1_k127_2175840_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 449.0
HKD1_k127_2175840_2 thiamine diphosphate biosynthetic process K03154 - - 0.00000000000005165 74.0
HKD1_k127_2190697_0 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002382 255.0
HKD1_k127_2190697_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000002404 228.0
HKD1_k127_2190697_10 - - - - 0.000000000002682 77.0
HKD1_k127_2190697_11 - - - - 0.000000001569 66.0
HKD1_k127_2190697_13 general secretion pathway protein K02456,K02457,K02458,K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000003955 60.0
HKD1_k127_2190697_14 PFAM General secretion pathway protein K K02460 - - 0.000018 56.0
HKD1_k127_2190697_2 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000001317 198.0
HKD1_k127_2190697_3 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000006024 189.0
HKD1_k127_2190697_4 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000007842 178.0
HKD1_k127_2190697_5 Type II secretion system (T2SS), protein J K02459 - - 0.0000000000000000000000002523 114.0
HKD1_k127_2190697_7 protein import K01179 - 3.2.1.4 0.000000000000003959 87.0
HKD1_k127_2190697_8 PFAM Type II secretion system protein E K02454 - - 0.000000000000009395 75.0
HKD1_k127_2190697_9 Prokaryotic N-terminal methylation motif K02457 - - 0.000000000001111 74.0
HKD1_k127_2207986_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 3.998e-221 702.0
HKD1_k127_2207986_1 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 523.0
HKD1_k127_2207986_2 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 392.0
HKD1_k127_2207986_3 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 388.0
HKD1_k127_2207986_4 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002064 276.0
HKD1_k127_2207986_5 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002551 266.0
HKD1_k127_2207986_6 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000002548 168.0
HKD1_k127_222919_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1561.0
HKD1_k127_222919_1 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 501.0
HKD1_k127_222919_10 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 306.0
HKD1_k127_222919_11 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 310.0
HKD1_k127_222919_12 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000423 262.0
HKD1_k127_222919_13 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000002328 225.0
HKD1_k127_222919_14 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.0000000000000000000000000000000000000000000000000000000463 200.0
HKD1_k127_222919_15 - - - - 0.000000000000000000000000000000000000000000000000000003033 196.0
HKD1_k127_222919_16 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000000003469 184.0
HKD1_k127_222919_17 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000004815 186.0
HKD1_k127_222919_18 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000009909 117.0
HKD1_k127_222919_19 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000000002015 99.0
HKD1_k127_222919_2 Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 481.0
HKD1_k127_222919_20 Protein of unknown function (DUF2905) - - - 0.00000000000000000008943 94.0
HKD1_k127_222919_22 - - - - 0.000000002956 64.0
HKD1_k127_222919_23 - - - - 0.000000004259 62.0
HKD1_k127_222919_25 Lipoprotein - - - 0.000009172 57.0
HKD1_k127_222919_3 binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 406.0
HKD1_k127_222919_4 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 394.0
HKD1_k127_222919_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 354.0
HKD1_k127_222919_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006537 350.0
HKD1_k127_222919_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 347.0
HKD1_k127_222919_8 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 351.0
HKD1_k127_222919_9 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 340.0
HKD1_k127_2242103_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.085e-223 700.0
HKD1_k127_2242103_1 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 557.0
HKD1_k127_2242103_2 Glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000000000000000000004553 215.0
HKD1_k127_2242103_3 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000007372 201.0
HKD1_k127_2242103_4 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000001127 190.0
HKD1_k127_2242103_5 PIN domain K07063 - - 0.00003266 51.0
HKD1_k127_2242103_6 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0001744 49.0
HKD1_k127_2250598_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.09e-202 646.0
HKD1_k127_2250598_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 349.0
HKD1_k127_2250598_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 312.0
HKD1_k127_2263809_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000003865 248.0
HKD1_k127_2263809_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000001299 230.0
HKD1_k127_2263809_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000001107 200.0
HKD1_k127_2263809_4 PFAM Glycosyl transferase, group 1 K12994 - 2.4.1.349 0.00000000000000000000000000000000000000002539 160.0
HKD1_k127_2274494_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 4.713e-212 666.0
HKD1_k127_2274494_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 473.0
HKD1_k127_2274494_10 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000004734 59.0
HKD1_k127_2274494_2 Flagellar basal body protein FlaE K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 375.0
HKD1_k127_2274494_3 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 343.0
HKD1_k127_2274494_4 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 312.0
HKD1_k127_2274494_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002886 267.0
HKD1_k127_2274494_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000008392 231.0
HKD1_k127_2274494_7 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000001837 164.0
HKD1_k127_2274494_8 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000003878 89.0
HKD1_k127_2274494_9 PFAM Flagellar hook-length control K02414 - - 0.0000000261 66.0
HKD1_k127_2274815_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1064.0
HKD1_k127_2274815_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 4.903e-282 898.0
HKD1_k127_2274815_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000004374 74.0
HKD1_k127_2274815_2 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 515.0
HKD1_k127_2274815_3 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 511.0
HKD1_k127_2274815_4 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 479.0
HKD1_k127_2274815_5 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 370.0
HKD1_k127_2274815_6 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 346.0
HKD1_k127_2274815_7 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 331.0
HKD1_k127_2274815_8 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000001331 234.0
HKD1_k127_2274815_9 LemA family K03744 - - 0.0000000000000000000000000002375 121.0
HKD1_k127_2275119_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 435.0
HKD1_k127_2275119_1 Putative peptidoglycan binding domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 413.0
HKD1_k127_2275119_2 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 367.0
HKD1_k127_2275119_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001865 259.0
HKD1_k127_2275119_4 GYD domain - - - 0.0000000000000000000000000000000000002251 144.0
HKD1_k127_2275119_5 COG2041 Sulfite oxidase and related enzymes - - - 0.00000000000838 68.0
HKD1_k127_2275119_6 WD40-like Beta Propeller K03641 - - 0.00001359 57.0
HKD1_k127_2290391_0 Belongs to the GPI family K01810 - 5.3.1.9 4.633e-269 838.0
HKD1_k127_2290391_1 cell redox homeostasis - - - 5.234e-220 691.0
HKD1_k127_2290391_2 Sensory domain found in PocR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 485.0
HKD1_k127_2290391_3 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 360.0
HKD1_k127_2290391_4 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000001009 267.0
HKD1_k127_2296295_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 4.839e-277 870.0
HKD1_k127_2296295_1 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 610.0
HKD1_k127_2296295_2 HDOD domain - - - 0.000000000000000000000000000000005962 134.0
HKD1_k127_2296295_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000001037 116.0
HKD1_k127_2296295_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000002683 114.0
HKD1_k127_2321275_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 424.0
HKD1_k127_2321275_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001085 269.0
HKD1_k127_2321275_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001839 267.0
HKD1_k127_2321275_3 transferase activity, transferring acyl groups - - - 0.00000000000000000000000000006107 128.0
HKD1_k127_2321275_4 Endoribonuclease L-PSP - - - 0.000000000000000000000000001257 114.0
HKD1_k127_2321275_5 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000002749 115.0
HKD1_k127_2321275_6 membrane K07058 - - 0.000000000000005552 86.0
HKD1_k127_2325057_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.387e-195 615.0
HKD1_k127_2325057_1 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000002735 203.0
HKD1_k127_2325057_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000003378 201.0
HKD1_k127_2325057_3 Tetratricopeptide repeat - - - 0.0000000000000000000001472 107.0
HKD1_k127_2325057_4 sigma-54 factor interaction domain-containing protein K02667 - - 0.000000000000001269 85.0
HKD1_k127_232583_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1196.0
HKD1_k127_232583_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.335e-276 865.0
HKD1_k127_232583_10 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.000000000005696 70.0
HKD1_k127_232583_11 PFAM membrane protein of K08972 - - 0.0003504 43.0
HKD1_k127_232583_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 392.0
HKD1_k127_232583_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 381.0
HKD1_k127_232583_4 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 377.0
HKD1_k127_232583_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 360.0
HKD1_k127_232583_6 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000001115 170.0
HKD1_k127_232583_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000002042 134.0
HKD1_k127_232583_8 PFAM PKD domain containing protein K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000007717 138.0
HKD1_k127_232583_9 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000001817 90.0
HKD1_k127_2329535_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 6.114e-277 866.0
HKD1_k127_2329535_1 Chemoreceptor zinc-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009541 275.0
HKD1_k127_2329535_2 - - - - 0.0000000000000000000000000000000000001076 146.0
HKD1_k127_2329535_3 GTP-binding protein TypA K06207 - - 0.0000000000000000003157 87.0
HKD1_k127_2329535_4 Cation efflux family - - - 0.000002238 51.0
HKD1_k127_2361654_0 Domain of unknown function (DUF4139) - - - 1.035e-201 638.0
HKD1_k127_2361654_1 - - - - 4.376e-194 612.0
HKD1_k127_2361654_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000002792 220.0
HKD1_k127_2361654_3 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000000000000000000000002521 205.0
HKD1_k127_2361654_4 Putative zinc-finger - - - 0.000000000000000000000000004094 123.0
HKD1_k127_2361654_5 endonuclease III K07457 - - 0.000000008684 56.0
HKD1_k127_2376336_0 phosphoglycolate phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 330.0
HKD1_k127_2376336_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 323.0
HKD1_k127_2376336_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000002325 222.0
HKD1_k127_2376336_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000001072 204.0
HKD1_k127_2376336_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000005778 156.0
HKD1_k127_2408381_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 459.0
HKD1_k127_2408381_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 408.0
HKD1_k127_2408381_10 PFAM flagellar basal body rod protein K02392 - - 0.00000000000000000000000000000000000000000001401 171.0
HKD1_k127_2408381_11 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000001285 154.0
HKD1_k127_2408381_12 HDOD domain - - - 0.00000000000000000000000000000000007247 145.0
HKD1_k127_2408381_13 - - - - 0.0000000000000000000000000001956 116.0
HKD1_k127_2408381_14 Molecular chaperone. Has ATPase activity K04079 - - 0.000000000000000000000000001611 113.0
HKD1_k127_2408381_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000001485 76.0
HKD1_k127_2408381_16 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00000000002418 74.0
HKD1_k127_2408381_17 Protein of unknown function, DUF488 - - - 0.000000835 50.0
HKD1_k127_2408381_18 - - - - 0.0007338 47.0
HKD1_k127_2408381_2 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 348.0
HKD1_k127_2408381_3 flagellar basal-body rod protein FlgG K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 333.0
HKD1_k127_2408381_4 Metal-dependent phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004803 242.0
HKD1_k127_2408381_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000135 240.0
HKD1_k127_2408381_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000004076 223.0
HKD1_k127_2408381_7 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.00000000000000000000000000000000000000000000000000000000002605 213.0
HKD1_k127_2408381_8 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000005074 209.0
HKD1_k127_2408381_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000004407 183.0
HKD1_k127_2411120_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.462e-307 953.0
HKD1_k127_2411120_1 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000003465 238.0
HKD1_k127_2411120_10 SMART protein phosphatase 2C domain protein - - - 0.000000005189 67.0
HKD1_k127_2411120_2 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000002647 233.0
HKD1_k127_2411120_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000003507 181.0
HKD1_k127_2411120_4 Methyltransferase domain - - - 0.00000000000000000000000000000000007972 143.0
HKD1_k127_2411120_5 Ferredoxin K17992 - 1.12.1.3 0.00000000000000000000000000000008562 130.0
HKD1_k127_2411120_6 Stringent starvation protein B K09985 - - 0.0000000000000000000000000614 112.0
HKD1_k127_2411120_7 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000001291 107.0
HKD1_k127_2411120_8 transcriptional regulator, arac family - - - 0.000000000000003262 87.0
HKD1_k127_2411120_9 Bacterial regulatory protein, Fis family - - - 0.0000000000001213 82.0
HKD1_k127_2411593_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 357.0
HKD1_k127_2411593_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005545 289.0
HKD1_k127_2411593_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002599 269.0
HKD1_k127_2411593_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000862 197.0
HKD1_k127_2411593_4 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000000000000000000001938 139.0
HKD1_k127_2411593_5 Response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000005419 107.0
HKD1_k127_2431626_0 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000785 246.0
HKD1_k127_2431626_1 Integral membrane sensor signal transduction histidine kinase - - - 0.000000000000000000000000000000000004243 153.0
HKD1_k127_2431626_2 Predicted membrane protein (DUF2318) - - - 0.0000958 51.0
HKD1_k127_2449829_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 3.898e-295 913.0
HKD1_k127_2449829_1 Dehydratase family K01687 - 4.2.1.9 1.413e-270 841.0
HKD1_k127_2449829_10 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000002084 237.0
HKD1_k127_2449829_11 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000001475 234.0
HKD1_k127_2449829_12 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000007807 205.0
HKD1_k127_2449829_13 BON domain - - - 0.000000000000000000000002507 110.0
HKD1_k127_2449829_14 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000319 103.0
HKD1_k127_2449829_15 Protein of unknown function (DUF465) K09794 - - 0.000000000000000001244 88.0
HKD1_k127_2449829_2 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 598.0
HKD1_k127_2449829_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 535.0
HKD1_k127_2449829_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 426.0
HKD1_k127_2449829_5 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 404.0
HKD1_k127_2449829_6 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 369.0
HKD1_k127_2449829_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 324.0
HKD1_k127_2449829_8 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 323.0
HKD1_k127_2449829_9 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001632 256.0
HKD1_k127_2458568_0 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 434.0
HKD1_k127_2458568_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002089 262.0
HKD1_k127_2458568_2 Putative transmembrane protein (Alph_Pro_TM) - - - 0.000000000000000000000000000000000000000000003129 174.0
HKD1_k127_2458568_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000000000001265 137.0
HKD1_k127_2458568_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000000001329 133.0
HKD1_k127_2458568_5 AMP binding - - - 0.00000000007836 68.0
HKD1_k127_2458568_6 NosL K19342 - - 0.000001777 55.0
HKD1_k127_2458568_7 Phosphoesterase family - - - 0.00004627 55.0
HKD1_k127_2526522_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.05e-279 872.0
HKD1_k127_2526522_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 5.746e-200 631.0
HKD1_k127_2526522_10 cell redox homeostasis K02199 - - 0.0000000000000000000000000000000000003934 148.0
HKD1_k127_2526522_11 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000000000002519 133.0
HKD1_k127_2526522_12 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000005158 108.0
HKD1_k127_2526522_13 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000009777 87.0
HKD1_k127_2526522_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 466.0
HKD1_k127_2526522_3 CO dehydrogenase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007734 284.0
HKD1_k127_2526522_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000002339 187.0
HKD1_k127_2526522_5 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000000000001021 179.0
HKD1_k127_2526522_6 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000126 157.0
HKD1_k127_2526522_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000004639 154.0
HKD1_k127_2526522_8 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000001542 153.0
HKD1_k127_2526522_9 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000000000000000000000000000000000001126 149.0
HKD1_k127_2527798_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 589.0
HKD1_k127_2527798_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 513.0
HKD1_k127_2527798_10 Domain of unknown function (DUF4412) - - - 0.0000000000000000000000000000000000007227 147.0
HKD1_k127_2527798_11 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000002587 127.0
HKD1_k127_2527798_12 peroxiredoxin activity - - - 0.000000000000000000000000000009934 124.0
HKD1_k127_2527798_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 499.0
HKD1_k127_2527798_3 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 397.0
HKD1_k127_2527798_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 310.0
HKD1_k127_2527798_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000001032 248.0
HKD1_k127_2527798_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000009455 228.0
HKD1_k127_2527798_7 Glycosyl transferase family group 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000001985 214.0
HKD1_k127_2527798_8 YbbR-like protein - - - 0.0000000000000000000000000000000000000000001224 166.0
HKD1_k127_2527798_9 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000006682 165.0
HKD1_k127_2574784_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 581.0
HKD1_k127_2574784_1 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 497.0
HKD1_k127_2574784_10 Peptidase family M48 - - - 0.00000003092 56.0
HKD1_k127_2574784_11 TPR repeat - - - 0.0000003439 62.0
HKD1_k127_2574784_12 YCII-related domain - - - 0.000008741 49.0
HKD1_k127_2574784_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 385.0
HKD1_k127_2574784_3 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 351.0
HKD1_k127_2574784_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001171 231.0
HKD1_k127_2574784_6 pathogenesis - - - 0.00000000000000000000000000000000000000000000000000000845 199.0
HKD1_k127_2574784_7 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000004419 157.0
HKD1_k127_2574784_8 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000000000001218 149.0
HKD1_k127_2574784_9 glycosyltransferase - - - 0.00000000000000000000000000002071 129.0
HKD1_k127_264376_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1450.0
HKD1_k127_264376_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 395.0
HKD1_k127_264376_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000006542 230.0
HKD1_k127_264376_3 YtkA-like - - - 0.0000000000000000000000000006295 117.0
HKD1_k127_264376_4 Protein of unknown function (DUF2892) - - - 0.00000000000000000001882 92.0
HKD1_k127_264376_5 Protein of unknown function with PCYCGC motif - - - 0.00000004278 58.0
HKD1_k127_2812076_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1498.0
HKD1_k127_2812076_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 553.0
HKD1_k127_2812076_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 449.0
HKD1_k127_2812076_3 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 393.0
HKD1_k127_2812076_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 338.0
HKD1_k127_2812076_5 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000813 244.0
HKD1_k127_2812076_6 nuclease K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.000000000000000000000000000000000000000001299 168.0
HKD1_k127_2863791_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 326.0
HKD1_k127_2863791_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000005713 182.0
HKD1_k127_2863791_2 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000418 137.0
HKD1_k127_2863791_3 - - - - 0.0000000003749 65.0
HKD1_k127_2863791_4 PFAM Peptidase M22, glycoprotease - - - 0.000009229 49.0
HKD1_k127_286697_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1065.0
HKD1_k127_286697_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.985e-212 668.0
HKD1_k127_286697_10 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 317.0
HKD1_k127_286697_11 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002254 274.0
HKD1_k127_286697_12 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007581 263.0
HKD1_k127_286697_13 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001194 259.0
HKD1_k127_286697_14 - - - - 0.0000000000000000000000000000000000000000001345 160.0
HKD1_k127_286697_15 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000003779 161.0
HKD1_k127_286697_16 Endonuclease containing a URI domain K07461 - - 0.0000000000000000000000000000000000001187 143.0
HKD1_k127_286697_17 - - - - 0.00000000000000000192 90.0
HKD1_k127_286697_18 AMP binding - - - 0.000001696 50.0
HKD1_k127_286697_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006633 544.0
HKD1_k127_286697_3 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 528.0
HKD1_k127_286697_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 491.0
HKD1_k127_286697_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 430.0
HKD1_k127_286697_6 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 422.0
HKD1_k127_286697_7 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 376.0
HKD1_k127_286697_8 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 356.0
HKD1_k127_286697_9 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 323.0
HKD1_k127_2976523_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 446.0
HKD1_k127_2976523_1 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005919 280.0
HKD1_k127_2976523_2 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001844 239.0
HKD1_k127_2976523_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000001205 179.0
HKD1_k127_2976523_4 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000006885 169.0
HKD1_k127_2976523_5 - - - - 0.000000000000000000000000000000000002631 142.0
HKD1_k127_2976523_6 HEPN domain - - - 0.00000000000000000003226 95.0
HKD1_k127_2976523_7 Nucleotidyltransferase domain - - - 0.00000000007094 67.0
HKD1_k127_2976523_8 DNA/RNA hybrid annealing activity K07012 - - 0.00005305 49.0
HKD1_k127_298878_0 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system K01990,K09691,K09693 - 3.6.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000004717 265.0
HKD1_k127_298878_1 glycosyl transferase family 2 K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001209 267.0
HKD1_k127_298878_2 PFAM Phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.000000000000000000000000000000000000000000000000416 183.0
HKD1_k127_298878_3 Sulfatase - - - 0.000000000000000000000000004129 128.0
HKD1_k127_298878_4 ABC-2 type transporter K01992,K09690 - - 0.0000000000000002721 81.0
HKD1_k127_298878_5 Glycosyl transferases group 1 - - - 0.0000259 51.0
HKD1_k127_3051088_0 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 297.0
HKD1_k127_3051088_1 PFAM Cytochrome b5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001468 287.0
HKD1_k127_3051088_2 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000000000003724 230.0
HKD1_k127_3051088_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003421 227.0
HKD1_k127_3051088_4 - - - - 0.000000000000000000000000000000000000000000000000000000584 196.0
HKD1_k127_3051088_5 Cytochrome C and Quinol oxidase polypeptide I K04561 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0055114 1.7.2.5 0.0000000000000000000000000000000000000641 147.0
HKD1_k127_3051088_6 4Fe-4S binding domain - - - 0.00000000000000000000000000003373 128.0
HKD1_k127_3051088_7 part of a sulfur-relay system - - - 0.000000000000000000000000003351 116.0
HKD1_k127_3086922_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 353.0
HKD1_k127_3086922_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 346.0
HKD1_k127_3094680_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 2.852e-249 777.0
HKD1_k127_3094680_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.495e-197 628.0
HKD1_k127_3094680_2 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 338.0
HKD1_k127_3094680_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000006009 233.0
HKD1_k127_3094680_4 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.00000000000001774 74.0
HKD1_k127_3094680_5 4Fe-4S dicluster domain - - - 0.0000003612 54.0
HKD1_k127_3094680_6 Cbb3-type cytochrome oxidase component FixQ - - - 0.0006648 44.0
HKD1_k127_3102535_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.198e-261 826.0
HKD1_k127_3102535_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.243e-199 627.0
HKD1_k127_3102535_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 455.0
HKD1_k127_3102535_3 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 323.0
HKD1_k127_3102535_4 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 304.0
HKD1_k127_3102535_5 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000000000000000000000000000000001488 160.0
HKD1_k127_3102535_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000000000000000000001696 103.0
HKD1_k127_3102535_8 TIGRFAM transcriptional regulator, AbrB family - - - 0.00007976 50.0
HKD1_k127_3106255_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1077.0
HKD1_k127_3106255_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 601.0
HKD1_k127_3106255_10 AsmA-like C-terminal region K07289 - - 0.000000000000000000000000000000000000001038 167.0
HKD1_k127_3106255_11 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000002834 150.0
HKD1_k127_3106255_13 - - - - 0.00000000000000000001592 96.0
HKD1_k127_3106255_14 - - - - 0.00000000000000000004505 91.0
HKD1_k127_3106255_15 Response regulator, receiver - - - 0.00000003305 66.0
HKD1_k127_3106255_2 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 445.0
HKD1_k127_3106255_3 Protein of unknown function (DUF3443) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 428.0
HKD1_k127_3106255_4 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 375.0
HKD1_k127_3106255_5 CHASE2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 363.0
HKD1_k127_3106255_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001212 258.0
HKD1_k127_3106255_7 TIGRFAM peptidase T-like protein K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000008424 243.0
HKD1_k127_3106255_8 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000005442 216.0
HKD1_k127_3106255_9 Protein of unknown function (DUF2844) - - - 0.0000000000000000000000000000000000000000000000009174 179.0
HKD1_k127_3106762_0 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 474.0
HKD1_k127_3106762_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 334.0
HKD1_k127_3106762_2 Enoyl-CoA hydratase/isomerase K11264 - 4.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007368 274.0
HKD1_k127_3106762_3 PFAM PhoH-like protein K07175 - - 0.0000000000000000000000000000000000001032 143.0
HKD1_k127_3106872_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.107e-321 1001.0
HKD1_k127_3106872_1 PFAM ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001702 244.0
HKD1_k127_3106872_2 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.0000000000000000000000000000000000000000000000006471 181.0
HKD1_k127_3106872_3 SMART serine threonine protein kinase - - - 0.000000000000000000000000000006308 128.0
HKD1_k127_3111343_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 337.0
HKD1_k127_3111343_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000006352 189.0
HKD1_k127_3111343_2 4Fe-4S binding domain - - - 0.000000000000002177 79.0
HKD1_k127_3111343_3 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.000000000000003747 77.0
HKD1_k127_3111343_4 Belongs to the sulfur carrier protein TusA family - - - 0.00000000279 61.0
HKD1_k127_3111343_5 DsrE/DsrF-like family K07235 - - 0.0000001141 58.0
HKD1_k127_3111343_6 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.0004865 51.0
HKD1_k127_3111343_7 DsrE/DsrF-like family K07236 - - 0.0006629 48.0
HKD1_k127_3111343_9 sulfur relay protein TusB DsrH K07237 - - 0.0009967 46.0
HKD1_k127_3135162_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1035.0
HKD1_k127_3135162_1 Endoribonuclease that initiates mRNA decay K18682 - - 1.117e-207 658.0
HKD1_k127_3135162_10 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.0000000000000000000000000009166 115.0
HKD1_k127_3135162_11 - - - - 0.000000000000005817 80.0
HKD1_k127_3135162_12 Regulatory protein RecX K03565 - - 0.0000000005351 68.0
HKD1_k127_3135162_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 514.0
HKD1_k127_3135162_3 PFAM type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 498.0
HKD1_k127_3135162_4 PFAM Metallophosphoesterase K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 325.0
HKD1_k127_3135162_5 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000005089 198.0
HKD1_k127_3135162_6 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000003086 196.0
HKD1_k127_3135162_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000000000000000000000659 146.0
HKD1_k127_3135162_8 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000005678 128.0
HKD1_k127_3135162_9 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000002072 126.0
HKD1_k127_3153782_0 type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 538.0
HKD1_k127_3153782_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 496.0
HKD1_k127_3153782_2 sugar transferase K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 421.0
HKD1_k127_3153782_3 PFAM Glycosyl transferase family 2 K12992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 304.0
HKD1_k127_3175778_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 432.0
HKD1_k127_3175778_1 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 317.0
HKD1_k127_3175778_2 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000000000000001616 205.0
HKD1_k127_3175778_3 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000006502 198.0
HKD1_k127_3175778_4 Domain of unknown function (DUF4388) - - - 0.0005061 44.0
HKD1_k127_3189840_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.877e-292 910.0
HKD1_k127_3189840_1 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 287.0
HKD1_k127_3189840_2 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000001196 85.0
HKD1_k127_3189840_3 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.00000000004918 65.0
HKD1_k127_3197415_0 SMART Elongator protein 3 MiaB NifB - - - 3.236e-210 681.0
HKD1_k127_3197415_1 FAD binding domain K00278 - 1.4.3.16 5.651e-204 646.0
HKD1_k127_3197415_2 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009557 613.0
HKD1_k127_3197415_3 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 373.0
HKD1_k127_3197415_4 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000017 276.0
HKD1_k127_3197415_5 - - - - 0.000000000000000000000000000000000000000000000000003833 185.0
HKD1_k127_3197415_6 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000001261 150.0
HKD1_k127_321715_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 557.0
HKD1_k127_321715_1 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 562.0
HKD1_k127_321715_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 472.0
HKD1_k127_321715_3 transcription factor binding - - - 0.000000000000000000000000000000000000000448 168.0
HKD1_k127_321715_4 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000005319 63.0
HKD1_k127_3244634_0 Surface antigen K07277 - - 8.195e-251 794.0
HKD1_k127_3244634_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 383.0
HKD1_k127_3244634_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 377.0
HKD1_k127_3244634_3 Psort location Cytoplasmic, score 8.96 K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008846 274.0
HKD1_k127_3244634_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000002303 235.0
HKD1_k127_3244634_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000003555 229.0
HKD1_k127_3244634_6 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000001772 216.0
HKD1_k127_3244634_7 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000000009102 139.0
HKD1_k127_3244634_8 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000005622 101.0
HKD1_k127_3247278_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 559.0
HKD1_k127_3247278_1 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 363.0
HKD1_k127_3247278_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 301.0
HKD1_k127_3247278_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000003964 220.0
HKD1_k127_3247278_4 nucleotide metabolic process - - - 0.00000000000000000000000000000000004368 144.0
HKD1_k127_3247278_5 Chemotaxis phosphatase CheX - - - 0.00000000000002776 77.0
HKD1_k127_3247278_6 peptidyl-tyrosine sulfation - - - 0.0000000008459 68.0
HKD1_k127_3261146_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 8.484e-273 854.0
HKD1_k127_3261146_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 2.111e-202 636.0
HKD1_k127_3261146_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 307.0
HKD1_k127_3261146_3 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009599 282.0
HKD1_k127_3261146_4 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000048 222.0
HKD1_k127_3261146_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000003562 207.0
HKD1_k127_3261146_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000002248 188.0
HKD1_k127_3261146_7 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000001016 171.0
HKD1_k127_3261146_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000007324 158.0
HKD1_k127_3261146_9 - - - - 0.0000000000004818 70.0
HKD1_k127_3267259_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 474.0
HKD1_k127_3267259_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 444.0
HKD1_k127_3267259_2 Sigma-54 interaction domain K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 425.0
HKD1_k127_3267259_3 Amino acid adenylation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000341 267.0
HKD1_k127_3267259_4 GAF domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000007358 265.0
HKD1_k127_3267259_5 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000000000000000002113 209.0
HKD1_k127_3272429_0 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009303 518.0
HKD1_k127_3272429_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 465.0
HKD1_k127_3272429_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000008728 153.0
HKD1_k127_3272429_3 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000004272 152.0
HKD1_k127_3272429_4 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000001871 89.0
HKD1_k127_3272429_5 Ami_2 - - - 0.0000000000000003085 93.0
HKD1_k127_3272429_6 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000005579 79.0
HKD1_k127_3272429_7 N-acetylglucosamine-1-phosphate uridyltransferase - - - 0.000000007634 68.0
HKD1_k127_3284079_0 Belongs to the peptidase S16 family - - - 5.337e-249 792.0
HKD1_k127_3284079_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.225e-209 653.0
HKD1_k127_3284079_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000008919 90.0
HKD1_k127_3284079_11 exonuclease K07502 - - 0.000000000000199 74.0
HKD1_k127_3284079_2 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 492.0
HKD1_k127_3284079_3 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 316.0
HKD1_k127_3284079_4 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000312 260.0
HKD1_k127_3284079_5 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.0000000000000000000000000000000000000000000000000000000000000000005646 236.0
HKD1_k127_3284079_6 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000006205 241.0
HKD1_k127_3284079_7 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000001661 207.0
HKD1_k127_3284079_8 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000001547 173.0
HKD1_k127_3284079_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000001113 143.0
HKD1_k127_3304536_0 GTP-binding protein TypA K06207 - - 6.956e-266 829.0
HKD1_k127_3304536_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 601.0
HKD1_k127_3304536_10 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000139 141.0
HKD1_k127_3304536_11 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000000006621 115.0
HKD1_k127_3304536_12 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00003916 48.0
HKD1_k127_3304536_2 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 492.0
HKD1_k127_3304536_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 454.0
HKD1_k127_3304536_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 447.0
HKD1_k127_3304536_5 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 411.0
HKD1_k127_3304536_6 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 323.0
HKD1_k127_3304536_7 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 320.0
HKD1_k127_3304536_8 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002206 282.0
HKD1_k127_3304536_9 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000004734 220.0
HKD1_k127_3317166_0 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 0.0 1215.0
HKD1_k127_3317166_1 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 346.0
HKD1_k127_3344641_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 3.944e-257 814.0
HKD1_k127_3344641_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.419e-199 629.0
HKD1_k127_3344641_10 deoxyribonuclease V activity K05982 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0034641,GO:0043170,GO:0043737,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000753 220.0
HKD1_k127_3344641_11 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000003832 212.0
HKD1_k127_3344641_12 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000009224 201.0
HKD1_k127_3344641_13 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000002206 164.0
HKD1_k127_3344641_14 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000002765 169.0
HKD1_k127_3344641_15 Transcriptional regulator, MerR family - - - 0.000000000000000000000000000000001268 134.0
HKD1_k127_3344641_16 O-Antigen ligase K02847 - - 0.00000000000000009079 93.0
HKD1_k127_3344641_17 Part of a membrane complex involved in electron transport K03615 - - 0.00000007335 54.0
HKD1_k127_3344641_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 528.0
HKD1_k127_3344641_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 424.0
HKD1_k127_3344641_4 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 376.0
HKD1_k127_3344641_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 305.0
HKD1_k127_3344641_6 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 314.0
HKD1_k127_3344641_7 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 304.0
HKD1_k127_3344641_8 transferase activity, transferring glycosyl groups K13500 - 2.4.1.175,2.4.1.226 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 289.0
HKD1_k127_3344641_9 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 285.0
HKD1_k127_3385861_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1112.0
HKD1_k127_3385861_1 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 424.0
HKD1_k127_3385861_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 411.0
HKD1_k127_3385861_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 330.0
HKD1_k127_3385861_4 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000000000000008728 153.0
HKD1_k127_3385861_5 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000001628 154.0
HKD1_k127_3385861_6 Thioredoxin-like - - - 0.0000000000000000000000000000000000005608 145.0
HKD1_k127_3385861_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000001252 116.0
HKD1_k127_3386572_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.931e-239 749.0
HKD1_k127_3386572_1 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 595.0
HKD1_k127_3386572_10 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000008822 91.0
HKD1_k127_3386572_2 Poly-beta-hydroxybutyrate polymerase N terminal K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 443.0
HKD1_k127_3386572_3 Poly-beta-hydroxybutyrate polymerase K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 383.0
HKD1_k127_3386572_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 332.0
HKD1_k127_3386572_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 308.0
HKD1_k127_3386572_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000225 274.0
HKD1_k127_3386572_7 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.00000000000000000000000007248 106.0
HKD1_k127_3386572_8 Domain of unknown function (DUF4870) - - - 0.000000000000000000001735 98.0
HKD1_k127_3386572_9 Transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' - - - 0.00000000000000000005375 90.0
HKD1_k127_3446218_0 PFAM Polysulphide reductase, NrfD K00185 - - 2.949e-230 726.0
HKD1_k127_3446218_1 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 598.0
HKD1_k127_3446218_2 - K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 424.0
HKD1_k127_3446218_3 COG2223 Nitrate nitrite transporter K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 421.0
HKD1_k127_3446218_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 377.0
HKD1_k127_3446218_5 helix_turn_helix, cAMP Regulatory protein K10914,K21563 - - 0.000000000000000000000000001715 121.0
HKD1_k127_3446218_6 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000004418 95.0
HKD1_k127_3463219_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.214e-320 1005.0
HKD1_k127_3463219_1 N-6 DNA Methylase K03427 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 314.0
HKD1_k127_3463219_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000001406 205.0
HKD1_k127_3463219_3 SMART HNH nuclease K07451 - - 0.000000000000000000000000000000000000008382 148.0
HKD1_k127_3469083_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 504.0
HKD1_k127_3469083_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 477.0
HKD1_k127_3469083_10 - - - - 0.0000000000000000000004522 98.0
HKD1_k127_3469083_11 - - - - 0.0000000000000000001174 97.0
HKD1_k127_3469083_12 Barstar (barnase inhibitor) K03623 - - 0.000000000000000805 80.0
HKD1_k127_3469083_13 Domain of unknown function (DUF309) K09763 - - 0.0000003744 57.0
HKD1_k127_3469083_15 PPIC-type PPIASE domain K03769,K03770 - 5.2.1.8 0.00003667 53.0
HKD1_k127_3469083_16 response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.000928 50.0
HKD1_k127_3469083_2 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 410.0
HKD1_k127_3469083_3 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 361.0
HKD1_k127_3469083_4 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 307.0
HKD1_k127_3469083_5 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 302.0
HKD1_k127_3469083_6 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000001401 203.0
HKD1_k127_3469083_7 ribonuclease - GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000003494 185.0
HKD1_k127_3469083_8 PFAM thioesterase superfamily K02614 - - 0.0000000000000000000000000000000000000003339 155.0
HKD1_k127_3469083_9 photosystem II stabilization K02237 - - 0.0000000000000000000000000000000001215 141.0
HKD1_k127_3621731_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1322.0
HKD1_k127_3621731_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 338.0
HKD1_k127_3621731_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001173 268.0
HKD1_k127_3621731_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000002605 213.0
HKD1_k127_3621731_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000001127 185.0
HKD1_k127_3621731_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000003524 147.0
HKD1_k127_3621731_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 0.000000000000000000000000000000000002291 138.0
HKD1_k127_3621731_7 structural constituent of ribosome K02913 - - 0.000000000000001496 78.0
HKD1_k127_3621731_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000255 71.0
HKD1_k127_3672351_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 456.0
HKD1_k127_3672351_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 374.0
HKD1_k127_3672351_2 Sensor histidine kinase, HAMP domain-containing - - - 0.0000000000000000000000000000000000000000000000000000004627 197.0
HKD1_k127_3672351_4 Prokaryotic cytochrome b561 - - - 0.0000000000000001218 87.0
HKD1_k127_3710684_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 567.0
HKD1_k127_3710684_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 556.0
HKD1_k127_3710684_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 526.0
HKD1_k127_3710684_3 Polysaccharide biosynthesis protein CapD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 510.0
HKD1_k127_3710684_4 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 430.0
HKD1_k127_3710684_5 His Kinase A (phosphoacceptor) domain K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002967 265.0
HKD1_k127_3710684_6 undecaprenyl-phosphate glucose phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001228 223.0
HKD1_k127_3710684_7 Transcription termination factor nusG - - - 0.0000000000000000000000000000000000000000000000007175 182.0
HKD1_k127_3710684_8 COGs COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00978 - 2.7.7.33 0.0000000000000002048 79.0
HKD1_k127_3710684_9 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000004277 80.0
HKD1_k127_377327_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1562.0
HKD1_k127_377327_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 517.0
HKD1_k127_377327_2 PFAM phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 422.0
HKD1_k127_377327_3 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000000000007562 228.0
HKD1_k127_377327_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000146 96.0
HKD1_k127_377327_5 - - - - 0.0000006716 54.0
HKD1_k127_3832947_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 435.0
HKD1_k127_3832947_1 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 402.0
HKD1_k127_3832947_10 denitrification pathway - - - 0.000000000000000007208 85.0
HKD1_k127_3832947_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 361.0
HKD1_k127_3832947_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 352.0
HKD1_k127_3832947_4 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 311.0
HKD1_k127_3832947_5 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000285 286.0
HKD1_k127_3832947_6 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001142 292.0
HKD1_k127_3832947_7 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000001605 208.0
HKD1_k127_3832947_8 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000001092 111.0
HKD1_k127_3832947_9 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.00000000000000000000009813 107.0
HKD1_k127_3845778_0 4Fe-4S dicluster domain - - - 5.58e-295 911.0
HKD1_k127_3845778_1 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 8.291e-209 655.0
HKD1_k127_3845778_10 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000000000000000000103 156.0
HKD1_k127_3845778_11 lyase activity - - - 0.000000000000000000000000000000000001685 146.0
HKD1_k127_3845778_13 lyase activity - - - 0.00000000000001721 79.0
HKD1_k127_3845778_2 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 3.542e-200 628.0
HKD1_k127_3845778_3 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 556.0
HKD1_k127_3845778_4 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 508.0
HKD1_k127_3845778_5 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 447.0
HKD1_k127_3845778_6 4 iron, 4 sulfur cluster binding K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 366.0
HKD1_k127_3845778_7 EVE domain - - - 0.000000000000000000000000000000000000000000000000000001722 194.0
HKD1_k127_3845778_8 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000000000000000000003983 179.0
HKD1_k127_3845778_9 - - - - 0.00000000000000000000000000000000000000000000000652 175.0
HKD1_k127_4001832_0 TonB-dependent Receptor Plug Domain K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 513.0
HKD1_k127_4001832_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 478.0
HKD1_k127_4001832_2 Metal-dependent phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001739 262.0
HKD1_k127_4001832_3 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000001746 249.0
HKD1_k127_4001832_4 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000001359 196.0
HKD1_k127_4001832_5 protein methyltransferase activity K00595 - 2.1.1.132 0.00000000000000000000000000000000000000001866 161.0
HKD1_k127_4001832_6 Cobalamin-5-phosphate synthase K02233 - 2.7.8.26 0.00000000000000000000000000000000000002647 154.0
HKD1_k127_4001832_7 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000001504 135.0
HKD1_k127_4001832_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000008603 63.0
HKD1_k127_4028536_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.272e-277 874.0
HKD1_k127_4028536_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 494.0
HKD1_k127_4028536_10 regulation of ruffle assembly - - - 0.000000000000000000000000000000000000000000000000000000000001222 217.0
HKD1_k127_4028536_11 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000009308 194.0
HKD1_k127_4028536_12 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000003059 193.0
HKD1_k127_4028536_13 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000005773 187.0
HKD1_k127_4028536_14 Universal stress protein family - - - 0.000000000000000000000000000000000000002179 151.0
HKD1_k127_4028536_15 YCII-related domain - - - 0.000000000000000000000000000000000001796 141.0
HKD1_k127_4028536_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000002615 139.0
HKD1_k127_4028536_17 ATPase or kinase K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000001367 123.0
HKD1_k127_4028536_18 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000008128 105.0
HKD1_k127_4028536_19 Psort location CytoplasmicMembrane, score K09153 - - 0.000000000000004141 81.0
HKD1_k127_4028536_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 314.0
HKD1_k127_4028536_20 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000001558 74.0
HKD1_k127_4028536_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 312.0
HKD1_k127_4028536_4 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000002544 259.0
HKD1_k127_4028536_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000008519 252.0
HKD1_k127_4028536_6 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000001764 267.0
HKD1_k127_4028536_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004704 252.0
HKD1_k127_4028536_8 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000000006401 218.0
HKD1_k127_4028536_9 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000002777 221.0
HKD1_k127_4039733_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 446.0
HKD1_k127_4039733_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002083 267.0
HKD1_k127_4039733_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000002617 161.0
HKD1_k127_4039733_3 Universal stress protein family - - - 0.000000000009081 72.0
HKD1_k127_4039733_4 Universal stress protein - - - 0.00000000002419 71.0
HKD1_k127_4062018_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.784e-249 784.0
HKD1_k127_4062018_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001624 270.0
HKD1_k127_4062018_2 metallopeptidase activity K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008424 243.0
HKD1_k127_4062018_3 - - - - 0.000000000000000000000000000000000000000000000001506 181.0
HKD1_k127_4065376_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1060.0
HKD1_k127_4065376_1 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000002402 212.0
HKD1_k127_4065376_2 - - - - 0.00000000000000000000000000000000000000000000000000005591 196.0
HKD1_k127_4065376_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000001704 152.0
HKD1_k127_4067168_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1080.0
HKD1_k127_4067168_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 492.0
HKD1_k127_4067168_10 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000114 194.0
HKD1_k127_4067168_11 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000002921 184.0
HKD1_k127_4067168_12 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000004036 185.0
HKD1_k127_4067168_13 - - - - 0.000000000000000000000000000000000000000002057 160.0
HKD1_k127_4067168_14 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000002491 140.0
HKD1_k127_4067168_15 - - - - 0.000000000000000000000000001968 113.0
HKD1_k127_4067168_16 Bacterial protein of unknown function (DUF937) - - - 0.0003676 45.0
HKD1_k127_4067168_2 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009647 428.0
HKD1_k127_4067168_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 417.0
HKD1_k127_4067168_4 Cobalamin (Vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 384.0
HKD1_k127_4067168_5 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 332.0
HKD1_k127_4067168_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 323.0
HKD1_k127_4067168_7 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001266 261.0
HKD1_k127_4067168_9 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000004562 190.0
HKD1_k127_4068072_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1164.0
HKD1_k127_4068072_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 423.0
HKD1_k127_4068072_10 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000004624 242.0
HKD1_k127_4068072_11 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000000000000000000000002526 226.0
HKD1_k127_4068072_12 - - - - 0.000000000000000000000000000000000000000000000000000000000001339 233.0
HKD1_k127_4068072_13 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000001253 214.0
HKD1_k127_4068072_14 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000000000000000000005079 197.0
HKD1_k127_4068072_15 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000000000006938 190.0
HKD1_k127_4068072_16 protocatechuate 3,4-dioxygenase - - - 0.0000000000000000000000000000000000000000000000002777 179.0
HKD1_k127_4068072_17 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000001223 171.0
HKD1_k127_4068072_18 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000006194 161.0
HKD1_k127_4068072_19 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000003601 155.0
HKD1_k127_4068072_2 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 322.0
HKD1_k127_4068072_20 Putative regulatory protein - - - 0.000000000000000000001158 98.0
HKD1_k127_4068072_21 LysM domain - - - 0.00000000007327 75.0
HKD1_k127_4068072_22 Protein of unknown function (DUF1573) - - - 0.0000000002945 62.0
HKD1_k127_4068072_24 YMGG-like Gly-zipper - - - 0.00003361 53.0
HKD1_k127_4068072_3 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 318.0
HKD1_k127_4068072_4 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 321.0
HKD1_k127_4068072_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 319.0
HKD1_k127_4068072_6 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 303.0
HKD1_k127_4068072_7 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005407 286.0
HKD1_k127_4068072_8 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004233 256.0
HKD1_k127_4068072_9 cytochrome complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004747 250.0
HKD1_k127_4084422_0 Belongs to the aldehyde dehydrogenase family K13821 - 1.2.1.88,1.5.5.2 6.778e-283 899.0
HKD1_k127_4084422_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 576.0
HKD1_k127_4084422_2 cheY-homologous receiver domain - - - 0.0000000000000000000000003328 110.0
HKD1_k127_4084422_3 Transcriptional regulator - - - 0.00000000000000000000003254 103.0
HKD1_k127_4084422_4 PFAM histidine kinase, HAMP region domain protein - - - 0.00000000000000000002663 97.0
HKD1_k127_4084422_5 ATPase (AAA superfamily K07133 - - 0.0000000000000009561 86.0
HKD1_k127_4084422_6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex - - - 0.00000000002378 66.0
HKD1_k127_4084422_7 PFAM GGDEF domain containing protein - - - 0.00000000003913 70.0
HKD1_k127_4084422_8 MORN repeat variant - - - 0.000003528 56.0
HKD1_k127_4091972_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 507.0
HKD1_k127_4091972_1 phosphorelay signal transduction system K07713,K07714,K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 454.0
HKD1_k127_4091972_10 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000006833 95.0
HKD1_k127_4091972_11 AhpC/TSA family K03386 - 1.11.1.15 0.00000000000000000007141 89.0
HKD1_k127_4091972_12 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000001657 83.0
HKD1_k127_4091972_13 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000009435 75.0
HKD1_k127_4091972_14 Flagellar assembly protein FliH K02411 - - 0.000000000004162 75.0
HKD1_k127_4091972_15 peptidyl-tyrosine sulfation - - - 0.00000004421 66.0
HKD1_k127_4091972_2 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 415.0
HKD1_k127_4091972_3 FliG middle domain K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 305.0
HKD1_k127_4091972_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004678 257.0
HKD1_k127_4091972_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000009813 229.0
HKD1_k127_4091972_6 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000000000000000000000002011 176.0
HKD1_k127_4091972_7 ATP synthase alpha/beta family, beta-barrel domain K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000003333 179.0
HKD1_k127_4091972_8 GYD domain - - - 0.00000000000000000000000000000000000000004313 153.0
HKD1_k127_4091972_9 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000001392 147.0
HKD1_k127_4105036_0 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 339.0
HKD1_k127_4105036_1 COG2942 N-acyl-D-glucosamine 2-epimerase K16213 - 5.1.3.11 0.000000000000000000000000000000000000000000000000000000000000185 229.0
HKD1_k127_4105036_2 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000001018 174.0
HKD1_k127_4105036_3 Glycosyltransferase family 10 (fucosyltransferase) C-term - - - 0.00000000000000003059 93.0
HKD1_k127_4111344_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 552.0
HKD1_k127_4111344_1 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 492.0
HKD1_k127_4111344_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 432.0
HKD1_k127_4111344_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000005257 218.0
HKD1_k127_4111344_4 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000003315 178.0
HKD1_k127_4111344_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000004542 138.0
HKD1_k127_4111344_6 - - - - 0.00000000000000000000000000000003217 132.0
HKD1_k127_4115971_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 389.0
HKD1_k127_4115971_2 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.000000000000000000000000000000000000000000000000006003 189.0
HKD1_k127_4115971_3 Belongs to the peptidase M16 family K07263 - - 0.00000000000001022 80.0
HKD1_k127_4115971_4 Putative regulatory protein - - - 0.00000001996 57.0
HKD1_k127_4122474_0 COG0058 Glucan phosphorylase - - - 1.121e-255 799.0
HKD1_k127_4122474_1 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 562.0
HKD1_k127_4122474_10 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000001531 185.0
HKD1_k127_4122474_11 MgtC family K07507 - - 0.00000000000000000000000000000000000001542 152.0
HKD1_k127_4122474_12 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000001082 116.0
HKD1_k127_4122474_13 amine dehydrogenase activity - - - 0.00000000000000000001811 106.0
HKD1_k127_4122474_14 GlcNAc-PI de-N-acetylase - - - 0.0000000000004711 82.0
HKD1_k127_4122474_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000002278 55.0
HKD1_k127_4122474_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 524.0
HKD1_k127_4122474_3 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 440.0
HKD1_k127_4122474_4 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 389.0
HKD1_k127_4122474_5 3-hydroxyacyl-CoA dehydrogenase K00074,K01782 - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 373.0
HKD1_k127_4122474_6 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009119 322.0
HKD1_k127_4122474_7 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 307.0
HKD1_k127_4122474_8 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000774 256.0
HKD1_k127_4122474_9 Putative regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000004042 199.0
HKD1_k127_4129564_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 3.925e-196 617.0
HKD1_k127_4129564_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 574.0
HKD1_k127_4129564_2 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 500.0
HKD1_k127_4129564_3 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 411.0
HKD1_k127_4129564_4 Metal-dependent phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 357.0
HKD1_k127_4129564_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704,K20453 - 4.2.1.33,4.2.1.35,4.2.1.85 0.000000000000000000000000000000000000000000000000000000000000001563 221.0
HKD1_k127_4129564_6 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000009994 144.0
HKD1_k127_4190902_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 502.0
HKD1_k127_4190902_1 ATP synthase subunit D K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000001909 239.0
HKD1_k127_4190902_2 PFAM PHP domain - - - 0.0000000000000000000000000000000000000000001177 166.0
HKD1_k127_4190902_3 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000001812 153.0
HKD1_k127_4190902_4 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000005983 72.0
HKD1_k127_4190902_5 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.000009908 55.0
HKD1_k127_4217990_0 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 329.0
HKD1_k127_4217990_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 307.0
HKD1_k127_4217990_2 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000002915 162.0
HKD1_k127_4217990_3 ACT domain protein - - - 0.0000147 54.0
HKD1_k127_4226134_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 502.0
HKD1_k127_4226134_1 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 481.0
HKD1_k127_4226134_2 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 379.0
HKD1_k127_4275315_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 355.0
HKD1_k127_4275315_1 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000178 241.0
HKD1_k127_4275315_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000006233 184.0
HKD1_k127_4285371_0 Molecular chaperone. Has ATPase activity K04079 - - 7.304e-274 852.0
HKD1_k127_4285371_1 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 2.953e-244 772.0
HKD1_k127_4285371_10 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 326.0
HKD1_k127_4285371_11 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 312.0
HKD1_k127_4285371_12 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000164 287.0
HKD1_k127_4285371_13 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000007552 266.0
HKD1_k127_4285371_14 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000005159 166.0
HKD1_k127_4285371_15 Beta Propeller - - - 0.000000000000000000000003131 105.0
HKD1_k127_4285371_16 - - - - 0.0000000000000000000001338 107.0
HKD1_k127_4285371_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.39e-239 750.0
HKD1_k127_4285371_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.493e-238 745.0
HKD1_k127_4285371_4 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.819e-230 729.0
HKD1_k127_4285371_5 GAF domain - - - 1.078e-206 687.0
HKD1_k127_4285371_6 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 557.0
HKD1_k127_4285371_7 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 555.0
HKD1_k127_4285371_8 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 436.0
HKD1_k127_4285371_9 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 428.0
HKD1_k127_4326545_0 PFAM V-type ATPase 116 kDa K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 594.0
HKD1_k127_4326545_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 504.0
HKD1_k127_4326545_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000000000008242 116.0
HKD1_k127_4326545_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000001335 116.0
HKD1_k127_4326545_5 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000000000000311 101.0
HKD1_k127_4329831_0 Sugar (and other) transporter K03446 - - 1.08e-242 758.0
HKD1_k127_4329831_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 471.0
HKD1_k127_4329831_10 PFAM MotA TolQ ExbB proton channel K02556 - - 0.0000000000000000000000000000003735 134.0
HKD1_k127_4329831_11 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000001135 122.0
HKD1_k127_4329831_12 Addiction module toxin, RelE StbE family K07334 - - 0.0000000000000000000004512 98.0
HKD1_k127_4329831_13 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000941 68.0
HKD1_k127_4329831_14 - - - - 0.0000001956 54.0
HKD1_k127_4329831_15 sequence-specific DNA binding - - - 0.000008044 52.0
HKD1_k127_4329831_2 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 470.0
HKD1_k127_4329831_3 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 434.0
HKD1_k127_4329831_4 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 399.0
HKD1_k127_4329831_5 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 313.0
HKD1_k127_4329831_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000004734 234.0
HKD1_k127_4329831_7 MarC family integral membrane protein - - - 0.0000000000000000000000000000000000000000005835 164.0
HKD1_k127_4329831_8 retrograde transport, endosome to Golgi K07095 - - 0.000000000000000000000000000000000000000001806 161.0
HKD1_k127_4329831_9 PFAM OmpA family K02557 - - 0.00000000000000000000000000000000002147 144.0
HKD1_k127_4387424_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 534.0
HKD1_k127_4387424_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 474.0
HKD1_k127_4387424_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 315.0
HKD1_k127_4387424_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 287.0
HKD1_k127_4387424_4 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000008483 166.0
HKD1_k127_4387424_5 Prokaryotic cytochrome b561 K00127 - - 0.00000000000000000000000000000000000001751 152.0
HKD1_k127_4387424_6 ferric iron binding K02380 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008199,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0051604,GO:0055114,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000004487 147.0
HKD1_k127_4437883_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 406.0
HKD1_k127_4437883_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001513 254.0
HKD1_k127_4437883_2 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000299 208.0
HKD1_k127_4437883_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000003379 195.0
HKD1_k127_4437883_4 - - - - 0.00000000000000000000000000000000872 132.0
HKD1_k127_4464649_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 584.0
HKD1_k127_4464649_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 319.0
HKD1_k127_4464649_2 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001578 246.0
HKD1_k127_4464649_3 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000002305 184.0
HKD1_k127_4464649_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000008356 187.0
HKD1_k127_4464649_5 CS domain K13993 - - 0.00000000000000000000000000001045 123.0
HKD1_k127_4468997_0 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 528.0
HKD1_k127_4468997_1 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000124 248.0
HKD1_k127_4468997_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000005537 103.0
HKD1_k127_4468997_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000001558 68.0
HKD1_k127_4543279_0 cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 414.0
HKD1_k127_4543279_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 355.0
HKD1_k127_4543279_10 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000009911 160.0
HKD1_k127_4543279_11 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000000005279 153.0
HKD1_k127_4543279_12 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000003842 149.0
HKD1_k127_4543279_13 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000001508 93.0
HKD1_k127_4543279_14 energy transducer activity K03646,K03832 - - 0.0000000000000828 81.0
HKD1_k127_4543279_15 - - - - 0.0007768 49.0
HKD1_k127_4543279_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 352.0
HKD1_k127_4543279_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 346.0
HKD1_k127_4543279_4 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001012 285.0
HKD1_k127_4543279_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003345 272.0
HKD1_k127_4543279_6 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000007356 242.0
HKD1_k127_4543279_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000002242 225.0
HKD1_k127_4543279_8 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000002361 216.0
HKD1_k127_4543279_9 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000000001233 175.0
HKD1_k127_4547532_0 ACT domain K00928 - 2.7.2.4 2.765e-202 635.0
HKD1_k127_4547532_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 606.0
HKD1_k127_4547532_2 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 550.0
HKD1_k127_4547532_3 Polysaccharide export protein K01991 - - 0.00000000000000000000000000000000000000000000000000027 198.0
HKD1_k127_4547532_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000003817 195.0
HKD1_k127_4547532_5 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.0000000000000000000006456 106.0
HKD1_k127_4547532_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00002587 57.0
HKD1_k127_4547532_7 iron ion homeostasis - - - 0.0001549 52.0
HKD1_k127_4558859_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 372.0
HKD1_k127_4558859_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 357.0
HKD1_k127_4558859_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 318.0
HKD1_k127_4558859_3 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000002162 216.0
HKD1_k127_4558859_6 protein secretion K03116,K03117 - - 0.000000000000003879 78.0
HKD1_k127_4558859_7 transferase activity, transferring glycosyl groups - - - 0.000000101 59.0
HKD1_k127_4623250_0 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 308.0
HKD1_k127_4623250_1 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004871 278.0
HKD1_k127_4623250_10 Cupin domain - - - 0.00000001996 57.0
HKD1_k127_4623250_11 trans-aconitate 2-methyltransferase activity K02169,K15256 - 2.1.1.197 0.000005384 49.0
HKD1_k127_4623250_12 - - - - 0.0009868 47.0
HKD1_k127_4623250_2 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000008642 266.0
HKD1_k127_4623250_3 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001645 245.0
HKD1_k127_4623250_4 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000001854 256.0
HKD1_k127_4623250_5 regulation of translation K03530 - - 0.00000000000000000000000000000000004937 135.0
HKD1_k127_4623250_6 Nitroreductase family - - - 0.0000000000000000000000000000000009026 137.0
HKD1_k127_4623250_7 - - - - 0.00000000000000000000000000003697 120.0
HKD1_k127_4623250_8 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.0000000000000000001931 94.0
HKD1_k127_4623250_9 electron transfer activity K05337,K17247 - - 0.000000009491 58.0
HKD1_k127_4702777_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 324.0
HKD1_k127_4702777_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000007233 203.0
HKD1_k127_4702777_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000008443 184.0
HKD1_k127_4702777_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000009996 171.0
HKD1_k127_4702777_4 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000002225 166.0
HKD1_k127_4702777_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000002712 149.0
HKD1_k127_4702777_6 peptidyl-tyrosine sulfation - - - 0.0000000003318 73.0
HKD1_k127_4720008_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 4.751e-194 623.0
HKD1_k127_4720008_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 569.0
HKD1_k127_4720008_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 563.0
HKD1_k127_4720008_3 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 480.0
HKD1_k127_4720008_4 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 353.0
HKD1_k127_4720008_5 Belongs to the TPP enzyme family K01577 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0008150,GO:0008152,GO:0008949,GO:0009056,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019752,GO:0019842,GO:0030554,GO:0030976,GO:0032553,GO:0032555,GO:0032559,GO:0033609,GO:0033611,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043531,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046872,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0097159,GO:0097367,GO:0104004,GO:1901265,GO:1901363,GO:1901575,GO:1901681 4.1.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001595 246.0
HKD1_k127_4720008_6 cobalamin synthesis protein, P47K - - - 0.0000000000000000000000000007002 122.0
HKD1_k127_4730161_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 447.0
HKD1_k127_4730161_1 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 319.0
HKD1_k127_4730161_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000001848 243.0
HKD1_k127_4730161_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000007358 169.0
HKD1_k127_4730161_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.00000000000000000000000000000000000007546 156.0
HKD1_k127_4730161_5 FtsX-like permease family K02004 - - 0.0000000000000000000000001469 106.0
HKD1_k127_4838326_0 Eco57I restriction-modification methylase - - - 6.15e-212 668.0
HKD1_k127_4838326_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 438.0
HKD1_k127_4838326_2 Type I restriction-modification system methyltransferase subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000011 282.0
HKD1_k127_4838326_3 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000002529 203.0
HKD1_k127_4838326_4 Ftsk_gamma K03466 - - 0.0000000000000000976 79.0
HKD1_k127_4838326_5 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000005576 74.0
HKD1_k127_48777_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1625.0
HKD1_k127_48777_1 Telomere recombination K04656 - - 1.043e-251 799.0
HKD1_k127_48777_10 Sigma-70 factor, region 1.1 K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 385.0
HKD1_k127_48777_11 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 323.0
HKD1_k127_48777_12 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 307.0
HKD1_k127_48777_13 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 303.0
HKD1_k127_48777_14 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 295.0
HKD1_k127_48777_15 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000187 295.0
HKD1_k127_48777_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 293.0
HKD1_k127_48777_17 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006984 245.0
HKD1_k127_48777_18 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000009378 241.0
HKD1_k127_48777_19 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000003843 235.0
HKD1_k127_48777_2 Cytochrome c554 and c-prime - - - 4.186e-243 759.0
HKD1_k127_48777_20 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000008674 207.0
HKD1_k127_48777_21 - - - - 0.00000000000000000000000000000000000000000000000000000000357 213.0
HKD1_k127_48777_22 PFAM MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000008069 201.0
HKD1_k127_48777_23 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000000000000009579 179.0
HKD1_k127_48777_24 PFAM Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000001865 186.0
HKD1_k127_48777_25 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000004978 175.0
HKD1_k127_48777_26 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000000001851 159.0
HKD1_k127_48777_27 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.000000000000000000000000000000000003287 144.0
HKD1_k127_48777_28 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000003534 132.0
HKD1_k127_48777_29 YtxH-like protein - - - 0.0000000000000000000000000000000799 127.0
HKD1_k127_48777_3 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 2.434e-210 666.0
HKD1_k127_48777_30 nickel cation binding K04651,K19640 - - 0.0000000000000000000000000003712 117.0
HKD1_k127_48777_31 electron transfer activity K00428 - 1.11.1.5 0.000000000000000000002802 98.0
HKD1_k127_48777_32 COG0526, thiol-disulfide isomerase and thioredoxins K21636 - 1.1.98.6 0.0000000000000000001835 97.0
HKD1_k127_48777_33 - - - - 0.00000000000004481 75.0
HKD1_k127_48777_35 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000002317 69.0
HKD1_k127_48777_4 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 574.0
HKD1_k127_48777_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 580.0
HKD1_k127_48777_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 488.0
HKD1_k127_48777_7 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 449.0
HKD1_k127_48777_8 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 421.0
HKD1_k127_48777_9 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 382.0
HKD1_k127_4911277_0 ABC transporter K06020 - 3.6.3.25 1.598e-314 969.0
HKD1_k127_4911277_1 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 389.0
HKD1_k127_4911277_2 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 322.0
HKD1_k127_4911277_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001529 284.0
HKD1_k127_4911277_4 ferredoxin-thioredoxin reductase activity - - - 0.0000000000000000000000000013 113.0
HKD1_k127_4911277_5 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.000000000000000000000009214 105.0
HKD1_k127_4911277_6 PFAM GAF domain protein - - - 0.00000000000000000000003853 115.0
HKD1_k127_4911277_7 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.0000000000000000000003296 99.0
HKD1_k127_4911277_9 phosphorelay sensor kinase activity - - - 0.000004328 59.0
HKD1_k127_4972633_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.316e-229 718.0
HKD1_k127_4972633_1 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 516.0
HKD1_k127_4972633_10 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.000000000000000000000000000000000000000005385 166.0
HKD1_k127_4972633_11 peroxiredoxin activity - - - 0.0000000000000000000000000000009831 127.0
HKD1_k127_4972633_13 - - - - 0.0000000000000000000009754 100.0
HKD1_k127_4972633_14 Regulatory protein, FmdB family - - - 0.000000000000000000006408 94.0
HKD1_k127_4972633_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 423.0
HKD1_k127_4972633_3 Dehydrogenase E1 component K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 413.0
HKD1_k127_4972633_4 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 402.0
HKD1_k127_4972633_5 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000004082 239.0
HKD1_k127_4972633_6 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000004641 243.0
HKD1_k127_4972633_7 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000005906 226.0
HKD1_k127_4972633_8 lactate metabolic process K11473,K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000652 230.0
HKD1_k127_4972633_9 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000001471 208.0
HKD1_k127_5053285_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 539.0
HKD1_k127_5053285_1 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 432.0
HKD1_k127_5053285_2 Chemotaxis protein methyltransferase K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 349.0
HKD1_k127_5053285_3 Cellulose biosynthesis protein BcsQ K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 291.0
HKD1_k127_5053285_4 Sigma-70, region 4 K02405 - - 0.000000000000000000000000000000000000000000000000000000001605 209.0
HKD1_k127_5053285_5 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000001235 185.0
HKD1_k127_5053285_6 Flagellar biosynthesis regulator FlhF K02404 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000006658 186.0
HKD1_k127_5053285_7 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000002729 158.0
HKD1_k127_5053285_8 FHIPEP family K02400 - - 0.000000000000006051 78.0
HKD1_k127_5080971_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 478.0
HKD1_k127_5080971_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 476.0
HKD1_k127_5080971_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 362.0
HKD1_k127_5080971_3 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 312.0
HKD1_k127_5080971_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535 - 3.6.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 302.0
HKD1_k127_5080971_5 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000258 285.0
HKD1_k127_5080971_6 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000249 245.0
HKD1_k127_5080971_7 PFAM transposase, IS4 family protein - - - 0.00000005856 57.0
HKD1_k127_5083596_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 418.0
HKD1_k127_5083596_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 399.0
HKD1_k127_5083596_2 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 338.0
HKD1_k127_5083596_3 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 328.0
HKD1_k127_5083596_4 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008137 280.0
HKD1_k127_5083596_5 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000001264 161.0
HKD1_k127_5083596_6 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000009307 115.0
HKD1_k127_5083596_7 type II secretion system protein E K02652 - - 0.000000000000000000000007389 109.0
HKD1_k127_5083596_8 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000000001557 94.0
HKD1_k127_5118668_0 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 375.0
HKD1_k127_5118668_1 domain, Protein K01176,K03332 - 3.2.1.1,3.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 333.0
HKD1_k127_5118668_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 299.0
HKD1_k127_5118668_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 294.0
HKD1_k127_5118668_4 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000009853 236.0
HKD1_k127_5118668_5 peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000007585 158.0
HKD1_k127_5118668_6 electron transfer activity K00428 - 1.11.1.5 0.000000000000000000000000005082 113.0
HKD1_k127_5118668_7 - - - - 0.0000008391 57.0
HKD1_k127_5125521_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 1.928e-227 719.0
HKD1_k127_5125521_1 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 444.0
HKD1_k127_5125521_2 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 388.0
HKD1_k127_5125521_3 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 330.0
HKD1_k127_5125521_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 316.0
HKD1_k127_5125521_5 TIGRFAM iron-sulfur cluster binding protein - - - 0.00000000000000000000000000000000000000000002173 169.0
HKD1_k127_5125521_6 PFAM Carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000000004254 151.0
HKD1_k127_5125521_7 PAS fold K11527,K20973 - 2.7.13.3 0.000131 49.0
HKD1_k127_5125521_8 PIN domain - - - 0.0007563 44.0
HKD1_k127_5143379_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000008877 221.0
HKD1_k127_5143379_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000006495 143.0
HKD1_k127_5143379_2 Sulphur transport K07112 - - 0.0000000000000000000000000000005963 138.0
HKD1_k127_5143379_3 Peptidase family M54 K06974 - - 0.00000000000000000000000000007745 123.0
HKD1_k127_5143379_5 - - - - 0.000003978 51.0
HKD1_k127_5143379_6 Belongs to the sulfur carrier protein TusA family - - - 0.00005449 52.0
HKD1_k127_5167939_0 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 595.0
HKD1_k127_5167939_1 With LivFGHM is involved in the high affinity leucine transport K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 489.0
HKD1_k127_5167939_10 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000003711 170.0
HKD1_k127_5167939_12 chemotaxis, protein K03776 - - 0.0003061 52.0
HKD1_k127_5167939_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 417.0
HKD1_k127_5167939_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 414.0
HKD1_k127_5167939_4 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 353.0
HKD1_k127_5167939_5 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 347.0
HKD1_k127_5167939_6 ABC transporter K01996,K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 314.0
HKD1_k127_5167939_7 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000003667 268.0
HKD1_k127_5167939_8 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002052 252.0
HKD1_k127_5191610_0 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 413.0
HKD1_k127_5191610_1 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 354.0
HKD1_k127_5191610_10 electron transfer activity K05337,K17247 - - 0.000000000000000000000000001978 111.0
HKD1_k127_5191610_11 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000211 112.0
HKD1_k127_5191610_12 Methyltransferase type 11 K07755 - 2.1.1.137 0.0008778 50.0
HKD1_k127_5191610_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 312.0
HKD1_k127_5191610_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003871 267.0
HKD1_k127_5191610_4 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000001725 212.0
HKD1_k127_5191610_5 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000003459 160.0
HKD1_k127_5191610_6 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.00000000000000000000000000000000000000002173 155.0
HKD1_k127_5191610_7 Nitroreductase family - - - 0.00000000000000000000000000000000000000002771 154.0
HKD1_k127_5191610_8 Protein of unknown function (DUF1284) K09706 - - 0.0000000000000000000000000000000005759 134.0
HKD1_k127_5191610_9 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.000000000000000000000000000000005761 130.0
HKD1_k127_5207493_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 533.0
HKD1_k127_5207493_1 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 428.0
HKD1_k127_5207493_2 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 398.0
HKD1_k127_5207493_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 385.0
HKD1_k127_5207493_4 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 364.0
HKD1_k127_5207493_5 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000001154 228.0
HKD1_k127_5207493_6 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000001955 189.0
HKD1_k127_5207493_7 PFAM Glucosamine-6-phosphate isomerases 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000000000000000000000001585 183.0
HKD1_k127_5207493_8 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000001237 159.0
HKD1_k127_5226742_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1216.0
HKD1_k127_5226742_1 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 613.0
HKD1_k127_5226742_10 Protein of unknown function DUF72 - - - 0.0000000001539 62.0
HKD1_k127_5226742_11 Binds directly to 16S ribosomal RNA K02968 - - 0.000000007808 61.0
HKD1_k127_5226742_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 607.0
HKD1_k127_5226742_3 Malate/L-lactate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 530.0
HKD1_k127_5226742_4 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 527.0
HKD1_k127_5226742_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 479.0
HKD1_k127_5226742_6 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000002947 223.0
HKD1_k127_5226742_7 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000007645 139.0
HKD1_k127_5226742_8 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.0000000000000000000000000002278 126.0
HKD1_k127_5227368_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 506.0
HKD1_k127_5227368_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 426.0
HKD1_k127_5227368_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 361.0
HKD1_k127_5227368_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000008255 234.0
HKD1_k127_5227368_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000001377 128.0
HKD1_k127_5227368_5 methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000599 60.0
HKD1_k127_5227368_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.00001815 49.0
HKD1_k127_5227368_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00006017 53.0
HKD1_k127_5241287_0 C-terminal, D2-small domain, of ClpB protein K03694 - - 3.135e-275 862.0
HKD1_k127_5241287_1 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 299.0
HKD1_k127_5241287_2 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007643 274.0
HKD1_k127_5241287_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000002607 104.0
HKD1_k127_5250816_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.081e-292 907.0
HKD1_k127_5250816_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 9.145e-200 628.0
HKD1_k127_5250816_2 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 346.0
HKD1_k127_5250816_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 316.0
HKD1_k127_5250816_4 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 298.0
HKD1_k127_5250816_5 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001041 261.0
HKD1_k127_5250816_6 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001618 273.0
HKD1_k127_5250816_7 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000001899 198.0
HKD1_k127_5250816_8 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000003273 161.0
HKD1_k127_5269169_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K03407 - 2.7.13.3 2.994e-198 633.0
HKD1_k127_5269169_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 502.0
HKD1_k127_5269169_2 archaeal or bacterial-type flagellum-dependent cell motility K03408,K03414 GO:0001539,GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032991,GO:0036211,GO:0040011,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0097588,GO:0098561,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 467.0
HKD1_k127_5269169_3 Chemotaxis protein methyltransferase K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 349.0
HKD1_k127_5269169_4 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 328.0
HKD1_k127_5269169_5 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000002323 184.0
HKD1_k127_5269169_6 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000199 158.0
HKD1_k127_5269169_7 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K03408 - - 0.000000000000000000000000000003988 121.0
HKD1_k127_5375750_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 569.0
HKD1_k127_5375750_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 469.0
HKD1_k127_5375750_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 389.0
HKD1_k127_5375750_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 302.0
HKD1_k127_5375750_4 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000000000000000004424 154.0
HKD1_k127_5375750_5 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000006564 113.0
HKD1_k127_5375750_6 - - - - 0.00000000506 63.0
HKD1_k127_5377325_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 584.0
HKD1_k127_5377325_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 503.0
HKD1_k127_5377325_10 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0017089,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.000001651 56.0
HKD1_k127_5377325_11 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07478 - - 0.00005724 46.0
HKD1_k127_5377325_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 479.0
HKD1_k127_5377325_3 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 480.0
HKD1_k127_5377325_4 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 372.0
HKD1_k127_5377325_5 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 289.0
HKD1_k127_5377325_6 OstA-like protein K09774 - - 0.0000000000000000000000000000000006345 136.0
HKD1_k127_5377325_7 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000009115 130.0
HKD1_k127_5377325_8 bacterial (prokaryotic) histone like domain K04764 - - 0.00000000000000000000000006413 110.0
HKD1_k127_5377325_9 - - - - 0.000000000000009754 76.0
HKD1_k127_5434779_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 3.797e-315 972.0
HKD1_k127_5434779_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.116e-246 770.0
HKD1_k127_5434779_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 590.0
HKD1_k127_5434779_3 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 501.0
HKD1_k127_5434779_4 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 363.0
HKD1_k127_5434779_5 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 342.0
HKD1_k127_5434779_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000007024 251.0
HKD1_k127_5434779_7 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000002406 201.0
HKD1_k127_5434779_8 Peptidase S24-like K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000006808 199.0
HKD1_k127_5434779_9 phosphatase activity K05967 - - 0.0000000000000000000000000000000000001299 154.0
HKD1_k127_5468523_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1132.0
HKD1_k127_5468523_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 503.0
HKD1_k127_5468523_10 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000409 193.0
HKD1_k127_5468523_11 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000000006091 193.0
HKD1_k127_5468523_12 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000005255 184.0
HKD1_k127_5468523_13 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.00000000000000000000000000000000000000000000000003954 186.0
HKD1_k127_5468523_14 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.000000000000000000000000000000000000000000000003074 182.0
HKD1_k127_5468523_15 heme-binding sites - - - 0.00000000000000000000000000000000000000003132 162.0
HKD1_k127_5468523_16 denitrification pathway - - - 0.000000000000000000000000000000000000000216 163.0
HKD1_k127_5468523_17 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000002801 113.0
HKD1_k127_5468523_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 466.0
HKD1_k127_5468523_3 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 462.0
HKD1_k127_5468523_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 438.0
HKD1_k127_5468523_5 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766 424.0
HKD1_k127_5468523_6 citrate synthase K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 401.0
HKD1_k127_5468523_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009204 273.0
HKD1_k127_5468523_8 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000002199 215.0
HKD1_k127_5468523_9 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.00000000000000000000000000000000000000000000000000001029 200.0
HKD1_k127_5595404_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 3.722e-221 696.0
HKD1_k127_5595404_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 604.0
HKD1_k127_5595404_10 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000008993 100.0
HKD1_k127_5595404_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 454.0
HKD1_k127_5595404_3 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000009181 245.0
HKD1_k127_5595404_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000006817 240.0
HKD1_k127_5595404_5 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000000008334 239.0
HKD1_k127_5595404_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000004717 223.0
HKD1_k127_5595404_7 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000002301 222.0
HKD1_k127_5595404_8 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000006564 200.0
HKD1_k127_5595404_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000005404 195.0
HKD1_k127_5637366_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 500.0
HKD1_k127_5637366_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 356.0
HKD1_k127_5637366_10 Chemotaxis protein CheW K03408 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009453,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0042333,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.00000000000000000000000000000001681 131.0
HKD1_k127_5637366_11 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000004768 136.0
HKD1_k127_5637366_12 PFAM CheW domain protein K03408 - - 0.0000000000000000000001159 107.0
HKD1_k127_5637366_13 cheY-homologous receiver domain K03413 - - 0.00000000004067 64.0
HKD1_k127_5637366_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 334.0
HKD1_k127_5637366_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 318.0
HKD1_k127_5637366_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001831 285.0
HKD1_k127_5637366_5 Pfam:Arch_ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000708 269.0
HKD1_k127_5637366_6 HEAT repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008441 279.0
HKD1_k127_5637366_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000006777 246.0
HKD1_k127_5637366_8 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000001618 173.0
HKD1_k127_5637366_9 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000001719 141.0
HKD1_k127_5654052_0 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000000000001042 178.0
HKD1_k127_5654052_1 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000009653 156.0
HKD1_k127_5654052_2 Predicted RNA-binding protein - - - 0.000000000000005225 76.0
HKD1_k127_5731718_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 4.057e-248 773.0
HKD1_k127_5731718_1 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 606.0
HKD1_k127_5731718_2 domain, Protein K01176,K03332 - 3.2.1.1,3.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 435.0
HKD1_k127_5731718_3 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001232 261.0
HKD1_k127_5731718_4 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000225 224.0
HKD1_k127_5798967_0 membrane - - - 8.111e-267 833.0
HKD1_k127_5798967_1 cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006345 250.0
HKD1_k127_5798967_2 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003114 249.0
HKD1_k127_5798967_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000006598 173.0
HKD1_k127_5798967_4 Universal stress protein family - - - 0.00000000000000000000000000003375 123.0
HKD1_k127_5798967_5 Sulphur transport K07112 - - 0.000000000000000003076 92.0
HKD1_k127_5798967_6 - - - - 0.0000000000000002313 85.0
HKD1_k127_5798967_7 Sulfur carrier protein which probably makes part of a sulfur-relay system K04085 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000002482 67.0
HKD1_k127_58034_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 529.0
HKD1_k127_58034_2 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000379 188.0
HKD1_k127_58034_3 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000211 140.0
HKD1_k127_58034_4 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000005039 133.0
HKD1_k127_58034_5 RNA-binding - - - 0.0000000000000000000000005451 111.0
HKD1_k127_58034_6 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000001037 70.0
HKD1_k127_5817531_0 DeoC/LacD family aldolase K08321,K11645 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.245,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 347.0
HKD1_k127_5817531_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 306.0
HKD1_k127_5817531_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000001991 207.0
HKD1_k127_5817531_3 Universal stress protein family K07090 - - 0.00000000000000000000000000000000000000000000000000000003778 207.0
HKD1_k127_585828_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 367.0
HKD1_k127_585828_1 Creatinase Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001034 287.0
HKD1_k127_585828_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000002109 180.0
HKD1_k127_585828_3 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000001462 178.0
HKD1_k127_585828_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000000003868 133.0
HKD1_k127_585828_5 Tetratricopeptide repeat - - - 0.000000000000000000000004803 113.0
HKD1_k127_585828_6 Roadblock/LC7 domain - - - 0.00000000000000000000006646 102.0
HKD1_k127_6045976_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008307 605.0
HKD1_k127_6045976_1 UPF0210 protein K09157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008678 556.0
HKD1_k127_6045976_10 Belongs to the UPF0237 family K07166 - - 0.0000000000000000000001271 99.0
HKD1_k127_6045976_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000151 82.0
HKD1_k127_6045976_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 346.0
HKD1_k127_6045976_3 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001827 246.0
HKD1_k127_6045976_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000001674 210.0
HKD1_k127_6045976_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000136 213.0
HKD1_k127_6045976_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000003744 189.0
HKD1_k127_6045976_7 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000001475 168.0
HKD1_k127_6045976_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000006983 142.0
HKD1_k127_6045976_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000008971 132.0
HKD1_k127_6104852_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.556e-217 703.0
HKD1_k127_6104852_1 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 418.0
HKD1_k127_6104852_2 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000552 245.0
HKD1_k127_6104852_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000005835 173.0
HKD1_k127_6104852_4 PAC sensor-containing diguanylate cyclase - - - 0.00000000000000000000000000000000000000001034 164.0
HKD1_k127_6104852_5 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000000008488 123.0
HKD1_k127_6104852_6 iron-sulfur cluster assembly - - - 0.000000000000000000000003774 103.0
HKD1_k127_6104852_7 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000009105 68.0
HKD1_k127_6104852_8 Ami_3 K01448 - 3.5.1.28 0.000004603 53.0
HKD1_k127_6124734_0 4Fe-4S binding domain - - - 4.672e-221 696.0
HKD1_k127_6124734_1 isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 473.0
HKD1_k127_6124734_10 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.000000000000000000000000000000000003081 148.0
HKD1_k127_6124734_11 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000003166 135.0
HKD1_k127_6124734_12 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000000003739 100.0
HKD1_k127_6124734_13 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000002138 99.0
HKD1_k127_6124734_14 integral membrane protein - - - 0.0000000000398 72.0
HKD1_k127_6124734_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000002674 60.0
HKD1_k127_6124734_16 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.00001145 50.0
HKD1_k127_6124734_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 458.0
HKD1_k127_6124734_3 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 402.0
HKD1_k127_6124734_4 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 342.0
HKD1_k127_6124734_5 TIGRFAM oligoendopeptidase, M3 family K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002341 267.0
HKD1_k127_6124734_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000005066 220.0
HKD1_k127_6124734_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000001332 207.0
HKD1_k127_6124734_8 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000002431 190.0
HKD1_k127_6124734_9 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000004249 162.0
HKD1_k127_6129359_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1125.0
HKD1_k127_6129359_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 580.0
HKD1_k127_6129359_2 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 395.0
HKD1_k127_6129359_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004022 265.0
HKD1_k127_6129359_4 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000000000000000000000000000714 225.0
HKD1_k127_6146506_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 6.311e-292 906.0
HKD1_k127_6146506_1 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 2.527e-222 701.0
HKD1_k127_6146506_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 371.0
HKD1_k127_6146506_3 Glycosyl hydrolase family 3 K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000000001646 219.0
HKD1_k127_6146506_4 Domain of unknown function (DUF1992) - - - 0.00000000000000000000000000000000000002619 149.0
HKD1_k127_6146506_5 Amidohydrolase family - - - 0.000000000000001469 88.0
HKD1_k127_6146506_6 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000001081 65.0
HKD1_k127_6146506_7 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051082,GO:0061077,GO:1990507 - 0.000007423 55.0
HKD1_k127_6158932_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.35e-289 912.0
HKD1_k127_6158932_1 Transport of potassium into the cell K03549 - - 2.15e-252 793.0
HKD1_k127_6158932_10 O-Antigen ligase - - - 0.000000000000000000000000000000000000000001463 173.0
HKD1_k127_6158932_11 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000000000000000000008342 124.0
HKD1_k127_6158932_12 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000001376 120.0
HKD1_k127_6158932_13 - - - - 0.0000000000000000000000004029 120.0
HKD1_k127_6158932_14 Ribbon-helix-helix protein, copG family - - - 0.00000000000000000000002456 101.0
HKD1_k127_6158932_15 cell cycle K05589,K12065,K13052 - - 0.00000000000000003315 85.0
HKD1_k127_6158932_2 Glycosyl hydrolase family 57 - - - 4.666e-226 721.0
HKD1_k127_6158932_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 574.0
HKD1_k127_6158932_4 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 561.0
HKD1_k127_6158932_5 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 557.0
HKD1_k127_6158932_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 482.0
HKD1_k127_6158932_7 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 338.0
HKD1_k127_6158932_8 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 299.0
HKD1_k127_6158932_9 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001503 268.0
HKD1_k127_6159940_0 helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 560.0
HKD1_k127_6159940_1 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 451.0
HKD1_k127_6159940_10 DNA restriction-modification system - GO:0000737,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006304,GO:0006308,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009036,GO:0009056,GO:0009057,GO:0009307,GO:0009987,GO:0015666,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044355,GO:0046483,GO:0046700,GO:0050896,GO:0071704,GO:0090304,GO:0090305,GO:0099046,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000007112 48.0
HKD1_k127_6159940_2 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 407.0
HKD1_k127_6159940_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 373.0
HKD1_k127_6159940_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003384 274.0
HKD1_k127_6159940_5 PINc domain ribonuclease K09006 - - 0.00000000000000000000000000000000000000000000000000000000000000001502 230.0
HKD1_k127_6159940_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000005266 191.0
HKD1_k127_6159940_7 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000006185 143.0
HKD1_k127_6159940_8 negative regulation of ribosome biogenesis K00969,K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 0.0000000000000000000000000000000001373 135.0
HKD1_k127_6159940_9 GDP-mannose mannosyl hydrolase activity - - - 0.00000000000000000001155 92.0
HKD1_k127_6207419_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 5.229e-205 646.0
HKD1_k127_6207419_1 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 395.0
HKD1_k127_6207419_2 Creatinase Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 292.0
HKD1_k127_6207419_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000236 251.0
HKD1_k127_6207419_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000002225 182.0
HKD1_k127_6207419_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000001399 178.0
HKD1_k127_6207419_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000005685 179.0
HKD1_k127_6207419_7 Roadblock/LC7 domain - - - 0.00000000000000000000004846 102.0
HKD1_k127_6207419_8 Tetratricopeptide repeat - - - 0.0000000000000000000000982 109.0
HKD1_k127_6207419_9 PFAM response regulator receiver - - - 0.00000000000000003449 90.0
HKD1_k127_621784_0 Protoporphyrinogen oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 349.0
HKD1_k127_621784_1 Sulphur transport - - - 0.000000000000000000000000000000000000000000000000000000000000000003677 231.0
HKD1_k127_621784_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000007778 182.0
HKD1_k127_621784_3 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000001732 104.0
HKD1_k127_621784_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000832 68.0
HKD1_k127_6219238_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 411.0
HKD1_k127_6219238_1 GAF domain K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 361.0
HKD1_k127_6219238_2 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000000665 168.0
HKD1_k127_6219238_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000714 163.0
HKD1_k127_6219238_4 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050,K15554 - - 0.0000000000000000000000000000000000000003768 160.0
HKD1_k127_6219238_5 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000004763 154.0
HKD1_k127_6219238_6 redox protein, regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000004305 152.0
HKD1_k127_6219238_7 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000000000000000000000004497 129.0
HKD1_k127_6230273_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1202.0
HKD1_k127_6230273_1 LysM domain K08307,K12204,K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 342.0
HKD1_k127_6230273_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004674 258.0
HKD1_k127_6284322_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 486.0
HKD1_k127_6284322_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 472.0
HKD1_k127_6284322_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 414.0
HKD1_k127_6284322_3 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 406.0
HKD1_k127_6284322_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 334.0
HKD1_k127_6284322_5 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000002992 203.0
HKD1_k127_6284322_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000005778 147.0
HKD1_k127_6284322_7 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000001571 123.0
HKD1_k127_6284322_8 Cytochrome c7 and related cytochrome c - - - 0.000000000000005465 81.0
HKD1_k127_6336988_0 Metal-dependent phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002509 271.0
HKD1_k127_6336988_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000001129 244.0
HKD1_k127_6336988_2 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000001154 123.0
HKD1_k127_6336988_3 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000009976 114.0
HKD1_k127_6336988_4 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000915 113.0
HKD1_k127_6336988_5 SMART protein phosphatase 2C domain protein - - - 0.000005231 59.0
HKD1_k127_6366001_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 506.0
HKD1_k127_6366001_1 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 328.0
HKD1_k127_6366001_2 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000000005056 115.0
HKD1_k127_6366001_3 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K04488,K13819 - - 0.000000000000000004974 84.0
HKD1_k127_6391317_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 1.202e-205 647.0
HKD1_k127_6391317_1 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 449.0
HKD1_k127_6391317_2 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 407.0
HKD1_k127_6391317_3 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 362.0
HKD1_k127_6391317_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 307.0
HKD1_k127_6391317_5 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000001866 200.0
HKD1_k127_6391317_6 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000001267 79.0
HKD1_k127_64215_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 8.536e-273 852.0
HKD1_k127_64215_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 557.0
HKD1_k127_64215_10 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K18330 - 1.12.1.3 0.000000000000000000000000000000000000000000000001046 184.0
HKD1_k127_64215_11 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000002023 175.0
HKD1_k127_64215_12 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000000000000000000000001107 160.0
HKD1_k127_64215_13 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.00000000000000000000000000000000000000006054 155.0
HKD1_k127_64215_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000001369 144.0
HKD1_k127_64215_15 zinc-ribbon domain - - - 0.0000000000000000000000000000000037 141.0
HKD1_k127_64215_16 DRTGG domain - - - 0.000000000000000000000000000003241 123.0
HKD1_k127_64215_17 DRTGG domain - - - 0.00000000000000000000000000001433 121.0
HKD1_k127_64215_18 Sigma-54 dependent response regulator K07714 - - 0.00000000000000000000000000004807 120.0
HKD1_k127_64215_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000003777 75.0
HKD1_k127_64215_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 552.0
HKD1_k127_64215_20 Transcriptional regulator, Crp Fnr family K10914 - - 0.00000000000003637 79.0
HKD1_k127_64215_3 response regulator K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 484.0
HKD1_k127_64215_4 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 347.0
HKD1_k127_64215_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004972 272.0
HKD1_k127_64215_6 proteolysis K07059 - - 0.00000000000000000000000000000000000000000000000000000000000001434 222.0
HKD1_k127_64215_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000004113 214.0
HKD1_k127_64215_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000001163 217.0
HKD1_k127_64215_9 PHP-associated K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000003003 209.0
HKD1_k127_6429971_0 Elongation factor SelB, winged helix K03833 - - 1.114e-211 675.0
HKD1_k127_6429971_1 homoserine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 511.0
HKD1_k127_6429971_10 Transcriptional regulatory protein, C terminal K07664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001202 257.0
HKD1_k127_6429971_11 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000002669 267.0
HKD1_k127_6429971_12 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002907 240.0
HKD1_k127_6429971_13 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000002746 236.0
HKD1_k127_6429971_14 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000004674 209.0
HKD1_k127_6429971_15 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000006854 207.0
HKD1_k127_6429971_16 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000001083 191.0
HKD1_k127_6429971_17 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000004659 195.0
HKD1_k127_6429971_18 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000001896 177.0
HKD1_k127_6429971_19 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000001561 164.0
HKD1_k127_6429971_2 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 472.0
HKD1_k127_6429971_20 RNA-binding protein containing a PIN domain K06962 - - 0.000000000000000000000000000000000000171 147.0
HKD1_k127_6429971_21 Glutathione peroxidase - - - 0.0000000000000000000000000000000000008347 146.0
HKD1_k127_6429971_22 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000004725 135.0
HKD1_k127_6429971_23 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000000000000005046 113.0
HKD1_k127_6429971_24 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000255 90.0
HKD1_k127_6429971_25 Belongs to the UPF0235 family K09131 - - 0.0000000000000003735 81.0
HKD1_k127_6429971_26 Protein of unknown function DUF86 - - - 0.0000000004006 61.0
HKD1_k127_6429971_27 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000107 56.0
HKD1_k127_6429971_3 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 437.0
HKD1_k127_6429971_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 363.0
HKD1_k127_6429971_5 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 357.0
HKD1_k127_6429971_6 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 338.0
HKD1_k127_6429971_7 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 327.0
HKD1_k127_6429971_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 327.0
HKD1_k127_6429971_9 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 317.0
HKD1_k127_6442504_0 Heat shock 70 kDa protein K04043 - - 0.0 1015.0
HKD1_k127_6442504_1 negative regulation of protein lipidation K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 585.0
HKD1_k127_6442504_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000008695 107.0
HKD1_k127_6442504_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 576.0
HKD1_k127_6442504_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 428.0
HKD1_k127_6442504_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 336.0
HKD1_k127_6442504_5 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 301.0
HKD1_k127_6442504_6 SGNH hydrolase-like domain, acetyltransferase AlgX K19295 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005472 273.0
HKD1_k127_6442504_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000005219 178.0
HKD1_k127_6442504_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000004218 167.0
HKD1_k127_6442930_0 membrane K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 376.0
HKD1_k127_6442930_1 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005003 244.0
HKD1_k127_6442930_2 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000002936 126.0
HKD1_k127_6442930_4 - - - - 0.00000001941 61.0
HKD1_k127_6455967_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 322.0
HKD1_k127_6455967_1 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000006233 227.0
HKD1_k127_6455967_2 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 0.000000000000000000000000000000000000000000000000001033 189.0
HKD1_k127_6455967_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000003308 173.0
HKD1_k127_6455967_4 PFAM Amidohydrolase 2 K01686 - 4.2.1.8 0.0000000000000000000000000000000007138 144.0
HKD1_k127_6455967_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000007239 126.0
HKD1_k127_6455967_6 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000001454 126.0
HKD1_k127_6478938_0 Nickel-dependent hydrogenase - - - 9.691e-199 627.0
HKD1_k127_6478938_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 521.0
HKD1_k127_6478938_11 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000203 116.0
HKD1_k127_6478938_12 TIGRFAM hydrogenase maturation protease K08315 - 3.4.23.51 0.0000000000000000000000306 104.0
HKD1_k127_6478938_13 - - - - 0.00000000002812 64.0
HKD1_k127_6478938_14 - - - - 0.000000002803 59.0
HKD1_k127_6478938_2 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 415.0
HKD1_k127_6478938_3 coenzyme F420 hydrogenase activity K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 407.0
HKD1_k127_6478938_4 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000302 258.0
HKD1_k127_6478938_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005853 239.0
HKD1_k127_6478938_6 PFAM periplasmic solute binding protein K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000005829 231.0
HKD1_k127_6478938_7 ABC 3 transport family K09816,K09819 - - 0.000000000000000000000000000000000000000000000000000000000000002073 227.0
HKD1_k127_6478938_8 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000001058 159.0
HKD1_k127_6478938_9 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000001018 136.0
HKD1_k127_6493368_0 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 371.0
HKD1_k127_6493368_1 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 314.0
HKD1_k127_6493368_2 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 293.0
HKD1_k127_6493368_3 Histidine kinase - - - 0.000000000000000000000000000000000000000004426 173.0
HKD1_k127_6493368_4 HAMP domain - - - 0.0000000000000000000000000007878 129.0
HKD1_k127_6531998_0 PFAM Fimbrial assembly K02461 - - 0.0000000000001687 83.0
HKD1_k127_6531998_1 Type II secretion system (T2SS), protein M subtype b - - - 0.0000008996 57.0
HKD1_k127_6598051_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 360.0
HKD1_k127_6598051_1 GAF domain K02482 - 2.7.13.3 0.000000000000005988 88.0
HKD1_k127_6598051_2 histidine kinase HAMP region domain protein K03406 - - 0.00000004927 66.0
HKD1_k127_6601446_0 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 436.0
HKD1_k127_6601446_1 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 399.0
HKD1_k127_6601446_2 Belongs to the SfsA family K06206 - - 0.00000000000000000000000009526 110.0
HKD1_k127_6601446_4 Copper chaperone K07213 - - 0.000005539 52.0
HKD1_k127_6609002_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 6.393e-277 859.0
HKD1_k127_6609002_1 Flavodoxin - - - 1.447e-205 645.0
HKD1_k127_6609002_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 477.0
HKD1_k127_6609002_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 307.0
HKD1_k127_6609002_4 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000004574 182.0
HKD1_k127_6609002_5 - - - - 0.0000000000000000000000000000000000000000004911 162.0
HKD1_k127_6609002_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000003799 133.0
HKD1_k127_6609002_7 rubredoxin - - - 0.0000000000000000001343 90.0
HKD1_k127_6609002_8 zinc-ribbon domain - - - 0.0000000000000004062 80.0
HKD1_k127_67161_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1057.0
HKD1_k127_67161_1 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000001513 212.0
HKD1_k127_67161_10 Protein of unknown function (DUF1573) - - - 0.0001659 51.0
HKD1_k127_67161_2 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000001086 210.0
HKD1_k127_67161_3 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000001312 151.0
HKD1_k127_67161_4 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000002963 157.0
HKD1_k127_67161_5 PFAM FeoA family protein K04758 - - 0.0000000000000000000000000000007104 123.0
HKD1_k127_67161_6 energy transducer activity K03646,K03832 - - 0.00000000000000000006145 100.0
HKD1_k127_67161_7 iron ion homeostasis K04758 - - 0.00000000000000005552 83.0
HKD1_k127_67161_9 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000001603 58.0
HKD1_k127_6745624_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 4.274e-200 653.0
HKD1_k127_6745624_1 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005598 231.0
HKD1_k127_6745624_2 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000003594 166.0
HKD1_k127_6745624_3 - - - - 0.00007796 47.0
HKD1_k127_675426_0 Adenylylsulphate kinase K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007631 277.0
HKD1_k127_675426_1 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002828 290.0
HKD1_k127_675426_2 PFAM inositol monophosphatase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001279 265.0
HKD1_k127_675426_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000001788 184.0
HKD1_k127_675426_4 Peptidase family M23 - - - 0.000000000000000000000000000000000000000009987 164.0
HKD1_k127_675426_5 Belongs to the bacterial flagellin family K02397 - - 0.00000000000000000002887 103.0
HKD1_k127_675426_6 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000000000003768 75.0
HKD1_k127_675426_7 Anti-sigma-28 factor, FlgM K02398 - - 0.0002229 48.0
HKD1_k127_6758300_0 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 331.0
HKD1_k127_6758300_1 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001358 288.0
HKD1_k127_6758300_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000001785 160.0
HKD1_k127_6758300_3 Universal stress protein family - - - 0.0000000000000000000000000000000000000003964 153.0
HKD1_k127_6758300_4 proteolysis K03665 - - 0.00000000000000000000000000000007082 130.0
HKD1_k127_6812238_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 9.312e-319 991.0
HKD1_k127_6812238_1 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 446.0
HKD1_k127_6812238_2 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000000000000000000001975 198.0
HKD1_k127_6812238_3 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000004236 156.0
HKD1_k127_6812238_4 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000267 126.0
HKD1_k127_6812238_5 acetolactate decarboxylase activity K01575 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605 4.1.1.5 0.0000000000000000000003275 105.0
HKD1_k127_6926610_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 437.0
HKD1_k127_6926610_1 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 406.0
HKD1_k127_6926610_10 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000001736 124.0
HKD1_k127_6926610_11 oligosaccharyl transferase activity - - - 0.000000000000000000000000001569 130.0
HKD1_k127_6926610_12 oligosaccharyl transferase activity - - - 0.000000000000000000000000009061 128.0
HKD1_k127_6926610_13 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.0000000000000000005128 97.0
HKD1_k127_6926610_14 Tetratricopeptide repeat - - - 0.0000000001599 75.0
HKD1_k127_6926610_15 Virilizer, N-terminal - GO:0000003,GO:0000375,GO:0000381,GO:0001510,GO:0001667,GO:0002064,GO:0002065,GO:0002066,GO:0003006,GO:0003674,GO:0003676,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0006928,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007530,GO:0007538,GO:0007539,GO:0007549,GO:0008150,GO:0008152,GO:0008380,GO:0009451,GO:0009888,GO:0009987,GO:0010467,GO:0010468,GO:0010631,GO:0016020,GO:0016021,GO:0016070,GO:0016071,GO:0016477,GO:0016556,GO:0016604,GO:0016607,GO:0018993,GO:0019219,GO:0019222,GO:0019953,GO:0022412,GO:0022414,GO:0030154,GO:0030707,GO:0030855,GO:0031224,GO:0031323,GO:0031440,GO:0031974,GO:0031981,GO:0032259,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0034641,GO:0034708,GO:0036396,GO:0040011,GO:0040029,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043484,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0044703,GO:0045293,GO:0046483,GO:0048024,GO:0048468,GO:0048477,GO:0048609,GO:0048856,GO:0048869,GO:0048870,GO:0050684,GO:0050789,GO:0050794,GO:0051171,GO:0051179,GO:0051252,GO:0051674,GO:0051704,GO:0060255,GO:0060429,GO:0065007,GO:0070013,GO:0071704,GO:0080009,GO:0080090,GO:0090130,GO:0090132,GO:0090304,GO:0097159,GO:0110104,GO:1900363,GO:1901360,GO:1901363,GO:1902494,GO:1903311,GO:1990234 - 0.0002646 54.0
HKD1_k127_6926610_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 350.0
HKD1_k127_6926610_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001466 289.0
HKD1_k127_6926610_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000002102 230.0
HKD1_k127_6926610_5 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000001597 216.0
HKD1_k127_6926610_6 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000001343 196.0
HKD1_k127_6926610_7 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000003273 192.0
HKD1_k127_6926610_8 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000000000305 149.0
HKD1_k127_6926610_9 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000002147 143.0
HKD1_k127_6986756_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.504e-238 751.0
HKD1_k127_6986756_1 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 558.0
HKD1_k127_6986756_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 381.0
HKD1_k127_6986756_3 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000005274 225.0
HKD1_k127_6986756_4 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000000000001557 186.0
HKD1_k127_6986756_5 Ppx/GppA phosphatase family K01524 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0040007,GO:0044237,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000002326 161.0
HKD1_k127_6986756_6 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases gamma subunit K00177 - 1.2.7.3 0.0000000000000000000000000000000000000001003 157.0
HKD1_k127_6986756_7 part of a sulfur-relay system - - - 0.000000000000000002679 85.0
HKD1_k127_7060702_0 NADH-quinone oxidoreductase K00341,K05568,K12139 - 1.6.5.3 9.491e-244 767.0
HKD1_k127_7060702_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 605.0
HKD1_k127_7060702_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000002465 126.0
HKD1_k127_7060702_12 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503 - - 0.0000000000000000000000001746 107.0
HKD1_k127_7060702_2 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 549.0
HKD1_k127_7060702_3 GHKL domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 538.0
HKD1_k127_7060702_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 459.0
HKD1_k127_7060702_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 439.0
HKD1_k127_7060702_6 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009982 256.0
HKD1_k127_7060702_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000008438 198.0
HKD1_k127_7060702_8 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000058 182.0
HKD1_k127_7060702_9 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000001212 147.0
HKD1_k127_7135709_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.337e-211 663.0
HKD1_k127_7135709_1 membrane transporter protein K07090 - - 4.954e-207 650.0
HKD1_k127_7135709_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005976 250.0
HKD1_k127_7135709_11 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007712 245.0
HKD1_k127_7135709_12 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000002167 231.0
HKD1_k127_7135709_13 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000215 212.0
HKD1_k127_7135709_14 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000000000000000009819 185.0
HKD1_k127_7135709_15 - - - - 0.000000000000000000000000000000000000000000000002898 176.0
HKD1_k127_7135709_16 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000001016 171.0
HKD1_k127_7135709_17 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000002963 164.0
HKD1_k127_7135709_18 helix_turn_helix gluconate operon transcriptional repressor K03710 - - 0.00000000000000000000000000000000003263 143.0
HKD1_k127_7135709_19 UTRA K03710 - - 0.0000000000000000000000000000000001018 142.0
HKD1_k127_7135709_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 8.153e-203 635.0
HKD1_k127_7135709_20 Protein of unknown function (DUF3187) - - - 0.000000000000000000000003254 114.0
HKD1_k127_7135709_21 AMP binding - - - 0.000000000000000000000008365 106.0
HKD1_k127_7135709_22 Pfam:DUF1049 - - - 0.0001734 48.0
HKD1_k127_7135709_3 phosphorelay signal transduction system K02584,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 491.0
HKD1_k127_7135709_4 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 473.0
HKD1_k127_7135709_5 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 470.0
HKD1_k127_7135709_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 393.0
HKD1_k127_7135709_7 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 365.0
HKD1_k127_7135709_8 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 289.0
HKD1_k127_7135709_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002744 276.0
HKD1_k127_7221410_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 455.0
HKD1_k127_7221410_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 316.0
HKD1_k127_7221410_2 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002489 285.0
HKD1_k127_7221410_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000001926 273.0
HKD1_k127_7221410_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000009615 228.0
HKD1_k127_7221410_5 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000002153 119.0
HKD1_k127_7221410_7 - - - - 0.00000000115 60.0
HKD1_k127_7327952_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 521.0
HKD1_k127_7327952_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 409.0
HKD1_k127_7327952_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002868 264.0
HKD1_k127_7327952_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000096 210.0
HKD1_k127_7327952_4 UDP-N-acetylmuramate-alanine ligase K01924 - 6.3.2.8 0.00000000002466 66.0
HKD1_k127_7358707_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 390.0
HKD1_k127_7358707_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 380.0
HKD1_k127_7358707_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 310.0
HKD1_k127_7358707_3 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000004218 213.0
HKD1_k127_7358707_4 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000002772 188.0
HKD1_k127_7358707_5 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000005791 175.0
HKD1_k127_7358707_6 META domain K03929 - - 0.00000000001632 75.0
HKD1_k127_7358707_8 Phosphoribosyl transferase domain K07100 - - 0.0004185 47.0
HKD1_k127_7394599_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 8.724e-297 921.0
HKD1_k127_7394599_1 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 9.653e-269 847.0
HKD1_k127_7394599_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 4.221e-197 634.0
HKD1_k127_7394599_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000001757 247.0
HKD1_k127_7394599_4 Methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000001698 233.0
HKD1_k127_7394599_5 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000000008365 121.0
HKD1_k127_7394599_6 Polysaccharide biosynthesis/export protein - - - 0.00000000000000000007148 96.0
HKD1_k127_7394599_7 iron ion homeostasis - - - 0.00002085 55.0
HKD1_k127_7395961_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 475.0
HKD1_k127_7395961_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 292.0
HKD1_k127_7395961_2 DivIVA protein K04074 - - 0.000000000000000000000000000000000000000000000000000000000000000008365 228.0
HKD1_k127_7395961_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000004175 127.0
HKD1_k127_7395961_4 YGGT family K02221 - - 0.00000000000000000000000000000005581 130.0
HKD1_k127_7395961_5 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000001222 125.0
HKD1_k127_7395961_6 HD domain - - - 0.000000000000000000000000002204 121.0
HKD1_k127_7434409_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 519.0
HKD1_k127_7434409_1 Bacterial Ig-like domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000651 262.0
HKD1_k127_7434409_2 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000004854 199.0
HKD1_k127_7434409_3 protein complex oligomerization - - - 0.000000000000000000000000000000001764 135.0
HKD1_k127_7434409_4 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000002437 82.0
HKD1_k127_7434409_5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000009832 73.0
HKD1_k127_7434409_6 DnaJ domain protein - - - 0.00000002331 66.0
HKD1_k127_7490187_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.043e-294 920.0
HKD1_k127_7490187_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 609.0
HKD1_k127_7490187_10 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000001002 124.0
HKD1_k127_7490187_11 Domain of unknown function (DUF370) K09777 - - 0.000000000000000000000000000003836 126.0
HKD1_k127_7490187_12 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000003104 116.0
HKD1_k127_7490187_13 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000001882 92.0
HKD1_k127_7490187_14 PFAM Pilus assembly protein PilO K02664 - - 0.00000000000002641 81.0
HKD1_k127_7490187_15 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000004961 79.0
HKD1_k127_7490187_16 Protein of unknown function (DUF721) - - - 0.00000000004605 70.0
HKD1_k127_7490187_17 Pilus assembly protein, PilP K02665 - - 0.0000000000806 70.0
HKD1_k127_7490187_18 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K13735 GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605 - 0.000000003057 69.0
HKD1_k127_7490187_19 His Kinase A (phosphoacceptor) domain - - - 0.000008277 56.0
HKD1_k127_7490187_2 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 391.0
HKD1_k127_7490187_3 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 354.0
HKD1_k127_7490187_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 324.0
HKD1_k127_7490187_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 328.0
HKD1_k127_7490187_6 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001637 267.0
HKD1_k127_7490187_7 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000009465 265.0
HKD1_k127_7490187_8 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000002288 210.0
HKD1_k127_7490187_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000001099 153.0
HKD1_k127_753938_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 3.586e-212 674.0
HKD1_k127_753938_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 380.0
HKD1_k127_753938_2 Rubrerythrin - - - 0.00000000000001218 79.0
HKD1_k127_753938_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000004406 60.0
HKD1_k127_7563912_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 548.0
HKD1_k127_7563912_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 392.0
HKD1_k127_7563912_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 391.0
HKD1_k127_7563912_3 Transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 321.0
HKD1_k127_7563912_4 HNH nucleases - - - 0.000000000000000000000000000000000000000004212 156.0
HKD1_k127_7626716_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 9.445e-298 920.0
HKD1_k127_7626716_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 7.673e-203 642.0
HKD1_k127_7626716_10 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000001071 157.0
HKD1_k127_7626716_11 Yqey-like protein K09117 - - 0.0000000000000000000000000000000003913 136.0
HKD1_k127_7626716_12 permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000008205 145.0
HKD1_k127_7626716_13 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000002453 91.0
HKD1_k127_7626716_14 peptidyl-tyrosine sulfation - - - 0.0000001892 52.0
HKD1_k127_7626716_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 482.0
HKD1_k127_7626716_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 443.0
HKD1_k127_7626716_4 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 404.0
HKD1_k127_7626716_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 411.0
HKD1_k127_7626716_6 Transcriptional regulator K11921,K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 396.0
HKD1_k127_7626716_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006126 284.0
HKD1_k127_7626716_8 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000009163 243.0
HKD1_k127_7626716_9 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000001298 203.0
HKD1_k127_7675764_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 565.0
HKD1_k127_7675764_1 Cytochrome C and Quinol oxidase polypeptide I K04561 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0055114 1.7.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 427.0
HKD1_k127_7675764_2 PFAM Cytochrome b5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007316 289.0
HKD1_k127_7675764_3 Ndr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008457 254.0
HKD1_k127_7675764_4 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000001678 200.0
HKD1_k127_7675764_5 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000005508 156.0
HKD1_k127_7675764_6 4Fe-4S binding domain - - - 0.000000000000000000000000000000000009346 148.0
HKD1_k127_7675764_7 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000008939 105.0
HKD1_k127_7675764_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000007555 79.0
HKD1_k127_7675764_9 Cupin 2, conserved barrel domain protein - - - 0.000001741 53.0
HKD1_k127_768373_0 Aminotransferase class-III K01845 - 5.4.3.8 1.083e-204 644.0
HKD1_k127_768373_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 596.0
HKD1_k127_768373_2 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 577.0
HKD1_k127_768373_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 465.0
HKD1_k127_768373_4 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 364.0
HKD1_k127_768373_5 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 326.0
HKD1_k127_768373_6 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000002542 204.0
HKD1_k127_768373_8 cytochrome c nitrate reductase, small subunit K15876 - - 0.00000004685 62.0
HKD1_k127_7684883_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 600.0
HKD1_k127_7684883_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 536.0
HKD1_k127_7684883_10 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006996 252.0
HKD1_k127_7684883_11 Vitamin K epoxide reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002057 256.0
HKD1_k127_7684883_12 PIN domain - - - 0.000000000000000000000000000002044 124.0
HKD1_k127_7684883_13 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000001938 73.0
HKD1_k127_7684883_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 443.0
HKD1_k127_7684883_3 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 418.0
HKD1_k127_7684883_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 412.0
HKD1_k127_7684883_5 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 389.0
HKD1_k127_7684883_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 325.0
HKD1_k127_7684883_7 Evidence 2b Function of strongly homologous gene K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 303.0
HKD1_k127_7684883_8 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 297.0
HKD1_k127_7684883_9 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001915 260.0
HKD1_k127_7699695_0 GHKL domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 542.0
HKD1_k127_7699695_1 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009997 262.0
HKD1_k127_7699695_3 RDD family - - - 0.000000000000000000000002399 106.0
HKD1_k127_7699695_4 response regulator K13599 - - 0.0003438 43.0
HKD1_k127_7702074_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 3.325e-195 621.0
HKD1_k127_7702074_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 523.0
HKD1_k127_7702074_2 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 413.0
HKD1_k127_7702074_3 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 353.0
HKD1_k127_7702074_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000913 285.0
HKD1_k127_7702074_5 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000001803 156.0
HKD1_k127_7702074_6 - - - - 0.000000000005034 73.0
HKD1_k127_77082_0 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 569.0
HKD1_k127_77082_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 484.0
HKD1_k127_77082_10 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000005305 171.0
HKD1_k127_77082_11 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000001588 149.0
HKD1_k127_77082_12 Methyltransferase domain - - - 0.000000000000000000000000000000005123 136.0
HKD1_k127_77082_13 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000005537 119.0
HKD1_k127_77082_14 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000009719 100.0
HKD1_k127_77082_2 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 484.0
HKD1_k127_77082_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 460.0
HKD1_k127_77082_4 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 372.0
HKD1_k127_77082_5 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 319.0
HKD1_k127_77082_6 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005843 280.0
HKD1_k127_77082_7 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003807 269.0
HKD1_k127_77082_8 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000001028 213.0
HKD1_k127_77082_9 COGs COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000086 209.0
HKD1_k127_77396_0 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 589.0
HKD1_k127_77396_1 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 348.0
HKD1_k127_785589_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.227e-302 946.0
HKD1_k127_785589_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 524.0
HKD1_k127_785589_2 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 492.0
HKD1_k127_785589_3 N-4 methylation of cytosine K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 445.0
HKD1_k127_785589_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 417.0
HKD1_k127_785589_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 335.0
HKD1_k127_785589_7 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000001249 119.0
HKD1_k127_785589_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00003648 51.0
HKD1_k127_793552_0 Histidine kinase - - - 5.643e-204 669.0
HKD1_k127_793552_1 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 293.0
HKD1_k127_793552_2 energy transducer activity K03832 - - 0.000000000000000000000000000000000000000000000171 172.0
HKD1_k127_793552_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000001598 125.0
HKD1_k127_793552_4 - - - - 0.00000000000000000000000000002156 117.0
HKD1_k127_90148_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000001603 209.0
HKD1_k127_90148_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000007162 219.0
HKD1_k127_90148_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000002051 159.0
HKD1_k127_90148_3 - - - - 0.000000000000000000000000000000000004954 155.0
HKD1_k127_90148_4 - - - - 0.00000000000000000001826 99.0
HKD1_k127_90148_5 Sporulation related domain K16081 - - 0.000001354 59.0