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Overview

ID MAG01715
Name HKD1_bin.31
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Vicinamibacteria
Order Vicinamibacterales
Family UBA2999
Genus Gp6-AA45
Species
Assembly information
Completeness (%) 100.0
Contamination (%) 5.19
GC content (%) 66.0
N50 (bp) 61,678
Genome size (bp) 5,520,440

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4452

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1000256_0 Domain of unknown function DUF87 K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 595.0
HKD1_k127_1000256_1 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 546.0
HKD1_k127_1000256_10 4Fe-4S dicluster domain K05524 - - 0.00000000000000000000000000000000000006105 145.0
HKD1_k127_1000256_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000004856 144.0
HKD1_k127_1000256_12 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000001723 150.0
HKD1_k127_1000256_13 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000001603 151.0
HKD1_k127_1000256_14 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.00000000000000000000000000001125 130.0
HKD1_k127_1000256_15 - - - - 0.00000000000000000001592 105.0
HKD1_k127_1000256_16 TonB dependent receptor - - - 0.00000000000006306 76.0
HKD1_k127_1000256_17 - - - - 0.000000000008435 70.0
HKD1_k127_1000256_18 Putative zinc-finger - - - 0.00000004258 64.0
HKD1_k127_1000256_19 - - - - 0.000001312 55.0
HKD1_k127_1000256_2 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 392.0
HKD1_k127_1000256_20 Putative adhesin - - - 0.000007447 57.0
HKD1_k127_1000256_21 Tetratricopeptide repeat - - - 0.0000161 57.0
HKD1_k127_1000256_3 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 341.0
HKD1_k127_1000256_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000008419 257.0
HKD1_k127_1000256_5 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001126 259.0
HKD1_k127_1000256_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000121 240.0
HKD1_k127_1000256_7 Copper binding periplasmic protein CusF K07152 - - 0.00000000000000000000000000000000000000000000000000001621 199.0
HKD1_k127_1000256_8 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000002051 163.0
HKD1_k127_1000256_9 RNA polymerase sigma factor K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000003544 158.0
HKD1_k127_1017637_0 Cytochrome c K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 350.0
HKD1_k127_1017637_1 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000000000000000000000007623 241.0
HKD1_k127_1065585_0 PFAM Peptidase M1, membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 2.084e-212 688.0
HKD1_k127_1065585_1 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 517.0
HKD1_k127_1065585_2 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV K08685 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 449.0
HKD1_k127_1065585_3 Tryptophan halogenase K21256 - - 0.00000000000000000000000002274 124.0
HKD1_k127_1105510_0 Cytochrome c554 and c-prime - - - 0.0 1152.0
HKD1_k127_1105510_1 Penicillin amidase K01434 - 3.5.1.11 0.0 1035.0
HKD1_k127_1105510_10 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 358.0
HKD1_k127_1105510_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 337.0
HKD1_k127_1105510_12 Protein of unknown function (DUF3443) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 329.0
HKD1_k127_1105510_13 Histidine kinase K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 310.0
HKD1_k127_1105510_14 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000019 256.0
HKD1_k127_1105510_15 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001772 256.0
HKD1_k127_1105510_16 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002318 239.0
HKD1_k127_1105510_17 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000004974 252.0
HKD1_k127_1105510_18 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000001167 238.0
HKD1_k127_1105510_19 ribonuclease inhibitor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000008909 226.0
HKD1_k127_1105510_2 peptidyl-tyrosine sulfation - - - 4.383e-297 970.0
HKD1_k127_1105510_20 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000008837 209.0
HKD1_k127_1105510_21 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000111 226.0
HKD1_k127_1105510_22 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000009811 204.0
HKD1_k127_1105510_23 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000000000004641 189.0
HKD1_k127_1105510_24 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000002692 184.0
HKD1_k127_1105510_26 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.0000000000000000000000000000000003013 143.0
HKD1_k127_1105510_27 cheY-homologous receiver domain - - - 0.0000000000000000000000000005556 117.0
HKD1_k127_1105510_28 Protein of unknown function (DUF2844) - - - 0.00000000000000000000000002416 119.0
HKD1_k127_1105510_29 Transcriptional regulator K04033 - - 0.00000000000000000000005155 110.0
HKD1_k127_1105510_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.741e-279 889.0
HKD1_k127_1105510_30 PFAM Tetratricopeptide - - - 0.00000000001335 77.0
HKD1_k127_1105510_31 Lipocalin-like domain - - - 0.000000002395 67.0
HKD1_k127_1105510_32 antisigma factor binding - - - 0.00000005207 64.0
HKD1_k127_1105510_33 Sulfotransferase family - - - 0.0000003119 63.0
HKD1_k127_1105510_34 salt-induced outer membrane protein K07283 - - 0.0000004425 61.0
HKD1_k127_1105510_35 Transposase domain (DUF772) K07487 - - 0.00007975 52.0
HKD1_k127_1105510_36 Cupin 2, conserved barrel domain protein K19547 - 5.3.3.19 0.0002413 52.0
HKD1_k127_1105510_4 MacB-like periplasmic core domain - - - 3.587e-273 865.0
HKD1_k127_1105510_5 ASPIC and UnbV - - - 9.372e-270 843.0
HKD1_k127_1105510_6 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 508.0
HKD1_k127_1105510_7 Periplasmic component of the Tol biopolymer transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 442.0
HKD1_k127_1105510_8 Capsule synthesis protein K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 439.0
HKD1_k127_1105510_9 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 416.0
HKD1_k127_1126995_0 Dehydrogenase K00117 - 1.1.5.2 3.417e-279 874.0
HKD1_k127_1126995_1 N-acetyldiaminopimelate deacetylase activity K12941 - - 5.664e-233 733.0
HKD1_k127_1126995_10 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 328.0
HKD1_k127_1126995_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 325.0
HKD1_k127_1126995_12 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 275.0
HKD1_k127_1126995_13 Diphthamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002825 279.0
HKD1_k127_1126995_14 TonB dependent receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004644 286.0
HKD1_k127_1126995_15 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000001454 248.0
HKD1_k127_1126995_16 COG3911 Predicted ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001335 239.0
HKD1_k127_1126995_17 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000007675 220.0
HKD1_k127_1126995_18 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000002958 201.0
HKD1_k127_1126995_19 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000006473 180.0
HKD1_k127_1126995_2 efflux transmembrane transporter activity - - - 4.24e-211 689.0
HKD1_k127_1126995_20 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.00000000000000000000000000000000000000006623 160.0
HKD1_k127_1126995_21 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000000000106 171.0
HKD1_k127_1126995_22 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000001582 163.0
HKD1_k127_1126995_23 DoxX - - - 0.000000000000000000000000000000000000004237 154.0
HKD1_k127_1126995_24 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000002296 144.0
HKD1_k127_1126995_25 PFAM heat shock protein DnaJ K04082 - - 0.000000000000000000000000000000006291 136.0
HKD1_k127_1126995_26 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.0000000000000000000000002855 108.0
HKD1_k127_1126995_27 OsmC-like protein K04063 - - 0.0000000000000000000000004082 111.0
HKD1_k127_1126995_28 FeS assembly protein IscX - - - 0.00000000000000000000001711 100.0
HKD1_k127_1126995_29 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000001533 76.0
HKD1_k127_1126995_3 electron transfer activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 614.0
HKD1_k127_1126995_30 protein maturation K13628 - - 0.0000000000003621 69.0
HKD1_k127_1126995_31 PFAM blue (type 1) copper domain protein - - - 0.00000000005759 74.0
HKD1_k127_1126995_32 - - - - 0.0000000001594 72.0
HKD1_k127_1126995_33 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K22110 - - 0.00000003619 60.0
HKD1_k127_1126995_34 Domain of unknown function (DUF4203) - - - 0.0000009782 58.0
HKD1_k127_1126995_4 heat shock protein 70 K04043,K04044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 548.0
HKD1_k127_1126995_5 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 476.0
HKD1_k127_1126995_6 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 439.0
HKD1_k127_1126995_7 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 353.0
HKD1_k127_1126995_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 342.0
HKD1_k127_1126995_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 328.0
HKD1_k127_1146503_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1239.0
HKD1_k127_1146503_1 Carboxypeptidase regulatory-like domain - - - 0.0 1142.0
HKD1_k127_1146503_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 378.0
HKD1_k127_1146503_11 PFAM Cellulose synthase operon K20543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 396.0
HKD1_k127_1146503_12 PFAM glycoside hydrolase family 8 K20542 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 362.0
HKD1_k127_1146503_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 348.0
HKD1_k127_1146503_14 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 356.0
HKD1_k127_1146503_15 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 333.0
HKD1_k127_1146503_16 Belongs to the N(4) N(6)-methyltransferase family K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 326.0
HKD1_k127_1146503_17 PFAM Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 316.0
HKD1_k127_1146503_18 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 319.0
HKD1_k127_1146503_19 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 299.0
HKD1_k127_1146503_2 TIGRFAM cellulose synthase catalytic subunit (UDP-forming) K00694 - 2.4.1.12 0.0 1059.0
HKD1_k127_1146503_20 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 289.0
HKD1_k127_1146503_21 Bacterial protein of unknown function (DUF839) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002501 285.0
HKD1_k127_1146503_22 molybdate abc transporter K02018,K15496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006175 269.0
HKD1_k127_1146503_23 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004687 273.0
HKD1_k127_1146503_24 extracellular solute-binding protein, family 1 K22003 - 5.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000109 267.0
HKD1_k127_1146503_25 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003278 258.0
HKD1_k127_1146503_26 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004283 278.0
HKD1_k127_1146503_27 prohibitin homologues - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000001196 262.0
HKD1_k127_1146503_28 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000005543 241.0
HKD1_k127_1146503_29 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001847 243.0
HKD1_k127_1146503_3 B12 binding domain - - - 3.78e-237 741.0
HKD1_k127_1146503_30 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000004942 241.0
HKD1_k127_1146503_31 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000002886 221.0
HKD1_k127_1146503_32 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000001063 229.0
HKD1_k127_1146503_33 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000985 212.0
HKD1_k127_1146503_34 - - - - 0.00000000000000000000000000000000000000000000000000000004806 207.0
HKD1_k127_1146503_35 - - - - 0.0000000000000000000000000000000000000000000000002565 192.0
HKD1_k127_1146503_36 - - - - 0.000000000000000000000000000000000000000000000001165 178.0
HKD1_k127_1146503_37 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000003765 185.0
HKD1_k127_1146503_38 PFAM Transcriptional regulator - - - 0.0000000000000000000000000000000000000000001057 175.0
HKD1_k127_1146503_39 - - - - 0.0000000000000000000000000000000000000000004589 166.0
HKD1_k127_1146503_4 Dehydrogenase K02030,K17760,K19713 - 1.1.9.1,1.8.2.2 1.387e-223 713.0
HKD1_k127_1146503_40 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000003656 169.0
HKD1_k127_1146503_41 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000002153 155.0
HKD1_k127_1146503_42 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000002169 152.0
HKD1_k127_1146503_43 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000001019 136.0
HKD1_k127_1146503_44 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000001326 137.0
HKD1_k127_1146503_45 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000003894 130.0
HKD1_k127_1146503_46 TOBE domain - - - 0.0000000000000000000000000000007457 129.0
HKD1_k127_1146503_47 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000001292 126.0
HKD1_k127_1146503_48 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000008931 131.0
HKD1_k127_1146503_49 cellulase activity - - - 0.000000000000000000000000002425 119.0
HKD1_k127_1146503_5 PFAM Peptidase M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 509.0
HKD1_k127_1146503_50 - - - - 0.00000000000000000000001341 105.0
HKD1_k127_1146503_51 BON domain - - - 0.0000000000000000000001434 107.0
HKD1_k127_1146503_52 oxidoreductase activity - - - 0.00000000000000000001019 106.0
HKD1_k127_1146503_53 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000003025 101.0
HKD1_k127_1146503_54 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000009176 91.0
HKD1_k127_1146503_55 Cytochrome C' - - - 0.000000000000000007764 94.0
HKD1_k127_1146503_56 - - - - 0.000000000000000008215 89.0
HKD1_k127_1146503_57 - - - - 0.00000000000000002605 91.0
HKD1_k127_1146503_58 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000002958 95.0
HKD1_k127_1146503_59 - - - - 0.000000000002762 78.0
HKD1_k127_1146503_6 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 511.0
HKD1_k127_1146503_60 The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor K13992 - - 0.0000000002215 70.0
HKD1_k127_1146503_61 Parallel beta-helix repeats - - - 0.000000000628 74.0
HKD1_k127_1146503_63 PFAM Response regulator receiver domain K15012 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.000000177 58.0
HKD1_k127_1146503_64 - - - - 0.000001146 58.0
HKD1_k127_1146503_65 Nodulation efficiency protein D - - - 0.00000251 59.0
HKD1_k127_1146503_7 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 462.0
HKD1_k127_1146503_8 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 427.0
HKD1_k127_1146503_9 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 422.0
HKD1_k127_1187515_0 cellulose binding - - - 0.0 1269.0
HKD1_k127_1187515_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.533e-223 712.0
HKD1_k127_1187515_10 - - - - 0.00000000000000000000000000000000000000000000000002085 205.0
HKD1_k127_1187515_11 YCII-related domain - - - 0.0000000000000000000000000000000000000008935 154.0
HKD1_k127_1187515_12 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000001047 126.0
HKD1_k127_1187515_13 CHRD domain - - - 0.00000000000000000000000000001171 132.0
HKD1_k127_1187515_14 DoxX-like family - - - 0.00000000000000000000000000003941 122.0
HKD1_k127_1187515_15 Translation initiation factor SUI1 K03113 - - 0.0000000000000000000000004888 110.0
HKD1_k127_1187515_16 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000001131 100.0
HKD1_k127_1187515_17 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.00000000000001837 80.0
HKD1_k127_1187515_18 - - - - 0.00001222 59.0
HKD1_k127_1187515_2 Dienelactone hydrolase family - - - 1.501e-219 701.0
HKD1_k127_1187515_3 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 467.0
HKD1_k127_1187515_4 Flavoprotein involved in K transport K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 437.0
HKD1_k127_1187515_5 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 359.0
HKD1_k127_1187515_6 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007664 232.0
HKD1_k127_1187515_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.000000000000000000000000000000000000000000000000000000000000007019 218.0
HKD1_k127_1187515_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342,K03703,K04096 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000006159 233.0
HKD1_k127_1187515_9 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000004069 199.0
HKD1_k127_1188600_0 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 431.0
HKD1_k127_1188600_1 Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 358.0
HKD1_k127_1188600_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000489 246.0
HKD1_k127_1188600_3 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000003531 226.0
HKD1_k127_1188600_4 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000008119 162.0
HKD1_k127_1188600_5 Phosphate-starvation-inducible E K13256 - - 0.000000000000000000000000000000008191 131.0
HKD1_k127_1188600_6 PFAM peptidase T2 asparaginase 2 K01444,K13051 - 3.4.19.5,3.5.1.26 0.00001787 54.0
HKD1_k127_1192163_0 domain, Protein - - - 1.374e-201 661.0
HKD1_k127_1263633_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 515.0
HKD1_k127_1263633_1 COG3119 Arylsulfatase A K01134 - 3.1.6.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 511.0
HKD1_k127_1263633_10 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000307 150.0
HKD1_k127_1263633_11 NUDIX domain - - - 0.0000000000000000000000000000001503 131.0
HKD1_k127_1263633_12 GYD domain - - - 0.00000000000000000000000001576 112.0
HKD1_k127_1263633_13 - - - - 0.000000003487 59.0
HKD1_k127_1263633_2 Protein of unknown function (DUF3089) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 419.0
HKD1_k127_1263633_3 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 409.0
HKD1_k127_1263633_4 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 327.0
HKD1_k127_1263633_5 PFAM Acetamidase Formamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002006 272.0
HKD1_k127_1263633_6 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005037 256.0
HKD1_k127_1263633_7 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000001173 188.0
HKD1_k127_1263633_8 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000006871 181.0
HKD1_k127_1263633_9 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.0000000000000000000000000000000000000006626 160.0
HKD1_k127_1264204_0 Zinc carboxypeptidase - - - 0.0 1150.0
HKD1_k127_1264204_1 esterase - - - 1.132e-243 766.0
HKD1_k127_1264204_10 PFAM membrane bound O-acyl transferase MBOAT K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 498.0
HKD1_k127_1264204_11 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 472.0
HKD1_k127_1264204_12 Short chain fatty K02106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 471.0
HKD1_k127_1264204_13 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 465.0
HKD1_k127_1264204_14 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 433.0
HKD1_k127_1264204_15 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 413.0
HKD1_k127_1264204_16 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 404.0
HKD1_k127_1264204_17 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 388.0
HKD1_k127_1264204_18 TIGRFAM threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 393.0
HKD1_k127_1264204_19 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 412.0
HKD1_k127_1264204_2 Amidohydrolase family - - - 7.181e-222 700.0
HKD1_k127_1264204_20 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 389.0
HKD1_k127_1264204_21 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 374.0
HKD1_k127_1264204_22 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 367.0
HKD1_k127_1264204_23 major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 372.0
HKD1_k127_1264204_24 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009841 347.0
HKD1_k127_1264204_25 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 329.0
HKD1_k127_1264204_26 Peptidase S9 prolyl oligopeptidase active site domain protein K01303 - 3.4.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 325.0
HKD1_k127_1264204_27 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 302.0
HKD1_k127_1264204_28 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002601 306.0
HKD1_k127_1264204_29 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006479 293.0
HKD1_k127_1264204_3 Oligopeptidase F K08602 - - 3.07e-216 689.0
HKD1_k127_1264204_30 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001805 284.0
HKD1_k127_1264204_31 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001326 280.0
HKD1_k127_1264204_32 Met-10+ like-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001781 256.0
HKD1_k127_1264204_33 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004282 252.0
HKD1_k127_1264204_34 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001208 259.0
HKD1_k127_1264204_35 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000446 220.0
HKD1_k127_1264204_36 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000001391 211.0
HKD1_k127_1264204_37 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.00000000000000000000000000000000000000000000000000000007146 219.0
HKD1_k127_1264204_38 pseudouridine synthase activity K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000001212 205.0
HKD1_k127_1264204_39 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000265 199.0
HKD1_k127_1264204_4 ABC transporter K15738 - - 2.305e-210 669.0
HKD1_k127_1264204_40 Rhodanese Homology Domain K01011,K01613 - 2.8.1.1,2.8.1.2,4.1.1.65 0.000000000000000000000000000000000000000000000000002999 208.0
HKD1_k127_1264204_41 TraB family K09973 - - 0.0000000000000000000000000000000000000000000000001385 191.0
HKD1_k127_1264204_42 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000216 181.0
HKD1_k127_1264204_43 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000000000000005247 180.0
HKD1_k127_1264204_44 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000006621 182.0
HKD1_k127_1264204_45 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000001153 190.0
HKD1_k127_1264204_46 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000006755 178.0
HKD1_k127_1264204_47 - - - - 0.0000000000000000000000000000000000000000000003679 189.0
HKD1_k127_1264204_48 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000002828 173.0
HKD1_k127_1264204_49 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000005455 163.0
HKD1_k127_1264204_5 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 602.0
HKD1_k127_1264204_50 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000001511 167.0
HKD1_k127_1264204_51 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000004177 153.0
HKD1_k127_1264204_52 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000004359 141.0
HKD1_k127_1264204_53 Protein of unknown function DUF45 - - - 0.00000000000000000000000000000000005849 142.0
HKD1_k127_1264204_54 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000009581 138.0
HKD1_k127_1264204_55 - - - - 0.00000000000000000000000000001693 129.0
HKD1_k127_1264204_56 - - - - 0.0000000000000000000000005429 121.0
HKD1_k127_1264204_57 Alpha/beta hydrolase family - - - 0.000000000000000000000003849 112.0
HKD1_k127_1264204_58 - - - - 0.00000000000000000000004257 102.0
HKD1_k127_1264204_6 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008561 598.0
HKD1_k127_1264204_60 Mannosyltransferase (PIG-V) - - - 0.00000000000000000004278 99.0
HKD1_k127_1264204_61 GtrA-like protein - - - 0.000000000000000004715 90.0
HKD1_k127_1264204_62 - - - - 0.0000000000000001247 83.0
HKD1_k127_1264204_63 Thermophilic metalloprotease (M29) - - - 0.0000000002174 72.0
HKD1_k127_1264204_64 Carrier of the growing fatty acid chain in fatty acid biosynthesis K03955 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000001154 62.0
HKD1_k127_1264204_65 Stress responsive A/B Barrel Domain - - - 0.00000001252 59.0
HKD1_k127_1264204_66 acyl carrier protein - - - 0.00000003504 59.0
HKD1_k127_1264204_68 - - - - 0.0003156 48.0
HKD1_k127_1264204_69 MacB-like periplasmic core domain K02004 - - 0.0006267 51.0
HKD1_k127_1264204_7 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 560.0
HKD1_k127_1264204_70 Outer membrane efflux protein - - - 0.0009779 51.0
HKD1_k127_1264204_8 Domain of unknown function (DUF3471) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 527.0
HKD1_k127_1264204_9 Aldo/keto reductase family K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 502.0
HKD1_k127_130231_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 572.0
HKD1_k127_130231_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 336.0
HKD1_k127_130231_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001686 250.0
HKD1_k127_130231_3 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000001853 182.0
HKD1_k127_130231_4 amine dehydrogenase activity - - - 0.000000000000000000000000000007987 131.0
HKD1_k127_130231_5 photosynthesis - - - 0.000000000000005715 86.0
HKD1_k127_130231_6 photosynthesis - - - 0.00000000000003199 79.0
HKD1_k127_1354547_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 1.166e-242 761.0
HKD1_k127_1354547_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 8.79e-210 668.0
HKD1_k127_1354547_10 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 409.0
HKD1_k127_1354547_11 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009754 381.0
HKD1_k127_1354547_12 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 352.0
HKD1_k127_1354547_13 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 354.0
HKD1_k127_1354547_14 Belongs to the binding-protein-dependent transport system permease family K10440,K17203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 327.0
HKD1_k127_1354547_15 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 321.0
HKD1_k127_1354547_16 Uncharacterized conserved protein (COG2071) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 308.0
HKD1_k127_1354547_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002148 263.0
HKD1_k127_1354547_18 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000003047 248.0
HKD1_k127_1354547_19 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000001804 181.0
HKD1_k127_1354547_2 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 594.0
HKD1_k127_1354547_20 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000001497 143.0
HKD1_k127_1354547_21 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000001073 112.0
HKD1_k127_1354547_22 Protein of unknown function (DUF664) - - - 0.00000000000006329 73.0
HKD1_k127_1354547_3 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 565.0
HKD1_k127_1354547_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 529.0
HKD1_k127_1354547_5 methyltransferase K20421 - 2.1.1.303 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 475.0
HKD1_k127_1354547_6 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 464.0
HKD1_k127_1354547_7 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 440.0
HKD1_k127_1354547_8 transport system, ATPase K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 432.0
HKD1_k127_1354547_9 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 419.0
HKD1_k127_1356917_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1672.0
HKD1_k127_1356917_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1185.0
HKD1_k127_1356917_10 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005141 278.0
HKD1_k127_1356917_11 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000663 269.0
HKD1_k127_1356917_12 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000003997 238.0
HKD1_k127_1356917_13 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000004965 235.0
HKD1_k127_1356917_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000007424 229.0
HKD1_k127_1356917_15 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000007635 153.0
HKD1_k127_1356917_16 Cyclic nucleotide-monophosphate binding domain K09766 - - 0.000000000000000000000000000000058 134.0
HKD1_k127_1356917_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000001235 123.0
HKD1_k127_1356917_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1034.0
HKD1_k127_1356917_3 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 2.821e-292 918.0
HKD1_k127_1356917_4 Phosphoenolpyruvate carboxykinase - - - 6.677e-290 904.0
HKD1_k127_1356917_5 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 3.787e-198 625.0
HKD1_k127_1356917_6 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 559.0
HKD1_k127_1356917_7 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 471.0
HKD1_k127_1356917_8 COG1680 Beta-lactamase class C and other penicillin binding proteins K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 442.0
HKD1_k127_1356917_9 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 370.0
HKD1_k127_1409140_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 374.0
HKD1_k127_1409140_1 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 334.0
HKD1_k127_1409140_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000002884 134.0
HKD1_k127_1409140_3 Phosphoesterase family - - - 0.000001053 54.0
HKD1_k127_1434466_0 cytochrome C - - - 0.0 1205.0
HKD1_k127_1434466_1 Protein of unknown function (DUF1595) - - - 1.805e-292 919.0
HKD1_k127_1434466_10 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 518.0
HKD1_k127_1434466_11 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 484.0
HKD1_k127_1434466_12 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 486.0
HKD1_k127_1434466_13 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 484.0
HKD1_k127_1434466_14 HpcH/HpaI aldolase/citrate lyase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 458.0
HKD1_k127_1434466_15 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 458.0
HKD1_k127_1434466_16 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 454.0
HKD1_k127_1434466_17 DegT/DnrJ/EryC1/StrS aminotransferase family K13010,K19430 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 448.0
HKD1_k127_1434466_18 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 442.0
HKD1_k127_1434466_19 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 428.0
HKD1_k127_1434466_2 Protein of unknown function (DUF1501) - - - 1.226e-245 764.0
HKD1_k127_1434466_20 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 417.0
HKD1_k127_1434466_21 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 437.0
HKD1_k127_1434466_22 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 409.0
HKD1_k127_1434466_23 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 389.0
HKD1_k127_1434466_24 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 376.0
HKD1_k127_1434466_25 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 362.0
HKD1_k127_1434466_26 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 353.0
HKD1_k127_1434466_27 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 345.0
HKD1_k127_1434466_28 chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 334.0
HKD1_k127_1434466_29 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 324.0
HKD1_k127_1434466_3 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 1.614e-215 681.0
HKD1_k127_1434466_30 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 336.0
HKD1_k127_1434466_31 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 304.0
HKD1_k127_1434466_32 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 304.0
HKD1_k127_1434466_33 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 301.0
HKD1_k127_1434466_34 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 290.0
HKD1_k127_1434466_35 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 295.0
HKD1_k127_1434466_36 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004634 277.0
HKD1_k127_1434466_37 Psort location Cytoplasmic, score K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001084 285.0
HKD1_k127_1434466_38 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001416 278.0
HKD1_k127_1434466_39 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001659 249.0
HKD1_k127_1434466_4 Protein of unknown function (DUF1552) - - - 1.073e-197 625.0
HKD1_k127_1434466_40 Subtilase family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007984 262.0
HKD1_k127_1434466_41 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.000000000000000000000000000000000000000000000000000000000000000000143 235.0
HKD1_k127_1434466_42 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002571 240.0
HKD1_k127_1434466_43 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000008202 241.0
HKD1_k127_1434466_44 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000001271 237.0
HKD1_k127_1434466_45 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000001352 223.0
HKD1_k127_1434466_46 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000009671 235.0
HKD1_k127_1434466_47 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000006558 217.0
HKD1_k127_1434466_48 PFAM phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000002273 207.0
HKD1_k127_1434466_49 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000000000000000000000000000000000000000000000003886 203.0
HKD1_k127_1434466_5 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 621.0
HKD1_k127_1434466_50 PFAM Multiple antibiotic resistance (MarC)-related K05595 - - 0.00000000000000000000000000000000000000000000000000000001924 204.0
HKD1_k127_1434466_51 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000006322 199.0
HKD1_k127_1434466_52 Bacterial sugar transferase K13012 - - 0.000000000000000000000000000000000000000000000000000006562 192.0
HKD1_k127_1434466_53 COG3258 Cytochrome c K19713 - 1.8.2.2 0.00000000000000000000000000000000000000000000000000004728 198.0
HKD1_k127_1434466_54 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000001884 189.0
HKD1_k127_1434466_55 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000000000000000008412 179.0
HKD1_k127_1434466_56 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000004709 192.0
HKD1_k127_1434466_57 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000002413 188.0
HKD1_k127_1434466_58 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000002155 168.0
HKD1_k127_1434466_59 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000004269 151.0
HKD1_k127_1434466_6 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 610.0
HKD1_k127_1434466_60 creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000599 159.0
HKD1_k127_1434466_61 DinB superfamily K07552 - - 0.0000000000000000000000000000000000001372 148.0
HKD1_k127_1434466_62 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000008209 159.0
HKD1_k127_1434466_63 O-Antigen ligase K02847 - - 0.0000000000000000000000000000000001852 149.0
HKD1_k127_1434466_64 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000002594 136.0
HKD1_k127_1434466_66 Ribosomal protein L11 methyltransferase (PrmA) K02169 - 2.1.1.197 0.00000000000000000000000000001964 125.0
HKD1_k127_1434466_67 Cupin domain - - - 0.0000000000000000000000000001504 118.0
HKD1_k127_1434466_68 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000002534 122.0
HKD1_k127_1434466_69 nucleotidyltransferase activity - - - 0.0000000000000000000000004189 118.0
HKD1_k127_1434466_7 Polysaccharide biosynthesis protein K01710,K15894,K15912,K19421 GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192 4.2.1.115,4.2.1.135,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 580.0
HKD1_k127_1434466_70 glucose sorbosone - - - 0.000000000000000000005211 108.0
HKD1_k127_1434466_72 Acetyltransferase (GNAT) domain - - - 0.0000000000007959 81.0
HKD1_k127_1434466_73 PFAM Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000001533 73.0
HKD1_k127_1434466_74 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.00000000001202 72.0
HKD1_k127_1434466_75 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000003075 75.0
HKD1_k127_1434466_76 Domain of unknown function (DUF4956) - - - 0.0000000005167 72.0
HKD1_k127_1434466_77 Belongs to the peptidase S26 family - - - 0.000000001789 66.0
HKD1_k127_1434466_78 solute binding protein K02035 - - 0.000000005836 68.0
HKD1_k127_1434466_79 PFAM 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.000000007376 65.0
HKD1_k127_1434466_8 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 557.0
HKD1_k127_1434466_81 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000009888 64.0
HKD1_k127_1434466_82 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000242 63.0
HKD1_k127_1434466_83 O-antigen polymerase K18814 - - 0.000006446 59.0
HKD1_k127_1434466_84 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000783 55.0
HKD1_k127_1434466_86 Myosin, heavy chain 7B, cardiac muscle, beta K10352,K17751 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030016,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0044424,GO:0044444,GO:0044464,GO:0097512,GO:0099080,GO:0099081,GO:0099512 - 0.0008381 44.0
HKD1_k127_1434466_9 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 517.0
HKD1_k127_1436384_0 PFAM Radical SAM - - - 1.275e-218 691.0
HKD1_k127_1436384_1 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00316 - 1.5.99.6 8.165e-200 644.0
HKD1_k127_1436384_10 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000002106 233.0
HKD1_k127_1436384_11 Putative zinc-finger - - - 0.000000000000000000000000000000000000000000000000000000006733 208.0
HKD1_k127_1436384_12 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000082 179.0
HKD1_k127_1436384_13 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000004833 181.0
HKD1_k127_1436384_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000003892 170.0
HKD1_k127_1436384_15 Ion channel - - - 0.0000000000000000000000000000000000003522 144.0
HKD1_k127_1436384_16 COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000008343 124.0
HKD1_k127_1436384_17 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000104 124.0
HKD1_k127_1436384_18 RNA recognition motif - - - 0.0000000000000000000000000005669 117.0
HKD1_k127_1436384_19 Cold shock protein domain - - - 0.000000000000000005974 93.0
HKD1_k127_1436384_2 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 601.0
HKD1_k127_1436384_20 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000003464 56.0
HKD1_k127_1436384_21 Glycosyltransferase family 87 - - - 0.0001648 53.0
HKD1_k127_1436384_3 Alkyl sulfatase dimerisation K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 529.0
HKD1_k127_1436384_4 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 479.0
HKD1_k127_1436384_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 452.0
HKD1_k127_1436384_6 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 405.0
HKD1_k127_1436384_7 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 316.0
HKD1_k127_1436384_8 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009357 310.0
HKD1_k127_1436384_9 Amino acid permease K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 309.0
HKD1_k127_1542385_0 NAD(P)-binding Rossmann-like domain - - - 5.463e-232 739.0
HKD1_k127_1542385_1 NAD(P)-binding Rossmann-like domain - - - 7.83e-218 694.0
HKD1_k127_1542385_10 Trehalose utilisation - - - 0.000000000000000000004142 96.0
HKD1_k127_1542385_11 long-chain fatty acid transport protein - - - 0.0000000002012 72.0
HKD1_k127_1542385_12 COG0457 FOG TPR repeat - - - 0.00000006837 66.0
HKD1_k127_1542385_2 NAD(P)-binding Rossmann-like domain - - - 1.958e-201 647.0
HKD1_k127_1542385_3 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 454.0
HKD1_k127_1542385_4 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 425.0
HKD1_k127_1542385_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 344.0
HKD1_k127_1542385_6 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001747 297.0
HKD1_k127_1542385_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006354 252.0
HKD1_k127_1542385_8 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000003883 232.0
HKD1_k127_1550702_0 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 422.0
HKD1_k127_1550702_1 Smr domain - - - 0.0000000000000000000000000000000000000000001202 168.0
HKD1_k127_1550702_2 Universal stress protein - - - 0.000000000000000000000000000009422 130.0
HKD1_k127_1550702_3 Cation transport ATPase (P-type) K01537 - 3.6.3.8 0.0000000000000000000000000005052 117.0
HKD1_k127_1550702_4 Belongs to the universal stress protein A family - - - 0.00000000000169 78.0
HKD1_k127_1550702_5 Universal stress protein family - - - 0.0000006168 54.0
HKD1_k127_157261_0 MacB-like periplasmic core domain - - - 4.425e-305 957.0
HKD1_k127_157261_1 COG2366 Protein related to penicillin acylase K01434 - 3.5.1.11 3.902e-284 898.0
HKD1_k127_157261_10 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 350.0
HKD1_k127_157261_11 Glucose / Sorbosone dehydrogenase K00117,K21430 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 340.0
HKD1_k127_157261_12 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 324.0
HKD1_k127_157261_13 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000674 249.0
HKD1_k127_157261_14 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006143 267.0
HKD1_k127_157261_15 Belongs to the bacterial solute-binding protein 9 family K02077,K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000004126 244.0
HKD1_k127_157261_16 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000005085 239.0
HKD1_k127_157261_17 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000001095 229.0
HKD1_k127_157261_18 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000001772 231.0
HKD1_k127_157261_19 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000001434 225.0
HKD1_k127_157261_2 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 544.0
HKD1_k127_157261_20 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K09817 - - 0.00000000000000000000000000000000000000000000000000002185 197.0
HKD1_k127_157261_21 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000001015 195.0
HKD1_k127_157261_22 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000002805 194.0
HKD1_k127_157261_23 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000001323 192.0
HKD1_k127_157261_24 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000001881 180.0
HKD1_k127_157261_25 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000001833 171.0
HKD1_k127_157261_26 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000002454 177.0
HKD1_k127_157261_27 Cupin domain - - - 0.000000000000000000000000000000000000001084 155.0
HKD1_k127_157261_28 Acetyltransferase (GNAT) family K03824 - - 0.00000000000000000000000000000000000002362 156.0
HKD1_k127_157261_29 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000004824 146.0
HKD1_k127_157261_3 Multicopper oxidase K04753 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 516.0
HKD1_k127_157261_30 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000009595 132.0
HKD1_k127_157261_32 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000001242 111.0
HKD1_k127_157261_33 PFAM SpoVT AbrB K07172,K18842 - - 0.00000000000000000002306 93.0
HKD1_k127_157261_34 AMP binding - - - 0.00000000000000002236 89.0
HKD1_k127_157261_35 SMART protein phosphatase 2C domain protein - - - 0.00000000000005515 81.0
HKD1_k127_157261_36 Amidohydrolase family - - - 0.0000000000002119 72.0
HKD1_k127_157261_37 Anti-sigma-K factor rskA - - - 0.0000000001104 74.0
HKD1_k127_157261_38 - - - - 0.00000003017 67.0
HKD1_k127_157261_39 PFAM PEGA domain - - - 0.000000923 61.0
HKD1_k127_157261_4 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 492.0
HKD1_k127_157261_40 Protein kinase domain - - - 0.000003209 60.0
HKD1_k127_157261_41 Gram-negative bacterial TonB protein C-terminal - - - 0.00006991 54.0
HKD1_k127_157261_42 HupE / UreJ protein - - - 0.00009826 54.0
HKD1_k127_157261_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 469.0
HKD1_k127_157261_6 cytochrome K17230 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 409.0
HKD1_k127_157261_7 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 374.0
HKD1_k127_157261_8 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 356.0
HKD1_k127_157261_9 Aldehyde oxidase and xanthine dehydrogenase K00256 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 377.0
HKD1_k127_1702445_0 Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA K00219,K09461 - 1.14.13.40,1.3.1.34 0.0 1186.0
HKD1_k127_1702445_1 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 413.0
HKD1_k127_1702445_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 411.0
HKD1_k127_1702445_3 PFAM AMP-dependent synthetase and ligase K08295 - 6.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 347.0
HKD1_k127_1702445_4 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 289.0
HKD1_k127_1702445_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 291.0
HKD1_k127_1702445_6 Belongs to the TPP enzyme family K13039 - 4.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 291.0
HKD1_k127_1702445_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000009502 196.0
HKD1_k127_1744140_0 Cytochrome c-type biogenesis protein K02198 - - 3.23e-242 775.0
HKD1_k127_1744140_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 519.0
HKD1_k127_1744140_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 486.0
HKD1_k127_1744140_3 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 364.0
HKD1_k127_1744140_4 Maf-like protein - - - 0.00000000000000000000000000000000000000000000000005092 184.0
HKD1_k127_1744140_5 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000005302 83.0
HKD1_k127_1744140_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000002303 70.0
HKD1_k127_1744140_7 Protein of unknown function (DUF721) - - - 0.000008911 52.0
HKD1_k127_1770495_0 MacB-like periplasmic core domain - - - 0.0 1030.0
HKD1_k127_1770495_1 Voltage gated chloride channel - - - 1.264e-255 801.0
HKD1_k127_1770495_10 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 379.0
HKD1_k127_1770495_11 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 379.0
HKD1_k127_1770495_12 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 376.0
HKD1_k127_1770495_13 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 350.0
HKD1_k127_1770495_14 Belongs to the pyruvate kinase family K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 357.0
HKD1_k127_1770495_15 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 350.0
HKD1_k127_1770495_16 PFAM peptidase K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 332.0
HKD1_k127_1770495_17 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 323.0
HKD1_k127_1770495_18 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 312.0
HKD1_k127_1770495_19 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 315.0
HKD1_k127_1770495_2 WD40-like Beta Propeller Repeat - - - 3.827e-229 744.0
HKD1_k127_1770495_20 PFAM Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 299.0
HKD1_k127_1770495_21 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 301.0
HKD1_k127_1770495_22 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001738 293.0
HKD1_k127_1770495_23 Belongs to the asparaginase 1 family K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001409 260.0
HKD1_k127_1770495_24 COG0210 Superfamily I DNA and RNA helicases K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000004605 243.0
HKD1_k127_1770495_25 Belongs to the DapB family K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000288 213.0
HKD1_k127_1770495_26 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000000006332 207.0
HKD1_k127_1770495_27 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000001919 218.0
HKD1_k127_1770495_28 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000006456 170.0
HKD1_k127_1770495_29 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000009941 161.0
HKD1_k127_1770495_3 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 577.0
HKD1_k127_1770495_30 PFAM O-methyltransferase - - - 0.00000000000000000000000000000000000000000223 163.0
HKD1_k127_1770495_31 COG3857 ATP-dependent nuclease, subunit B K16899 - 3.6.4.12 0.00000000000000000000000000000000000258 160.0
HKD1_k127_1770495_33 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000999 115.0
HKD1_k127_1770495_34 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000441 78.0
HKD1_k127_1770495_35 - - - - 0.000000009261 61.0
HKD1_k127_1770495_36 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000003584 60.0
HKD1_k127_1770495_37 Protein of unknown function (DUF3347) - - - 0.0000001369 64.0
HKD1_k127_1770495_39 Activator of Hsp90 ATPase 1 family protein - - - 0.0003717 49.0
HKD1_k127_1770495_4 ATP dependent DNA ligase C terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 504.0
HKD1_k127_1770495_5 ATPase domain of DNA mismatch repair MUTS family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 500.0
HKD1_k127_1770495_6 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 482.0
HKD1_k127_1770495_7 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 445.0
HKD1_k127_1770495_8 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 422.0
HKD1_k127_1770495_9 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 409.0
HKD1_k127_17747_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1504.0
HKD1_k127_17747_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1161.0
HKD1_k127_17747_10 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 591.0
HKD1_k127_17747_11 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 578.0
HKD1_k127_17747_12 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 559.0
HKD1_k127_17747_13 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 528.0
HKD1_k127_17747_14 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 480.0
HKD1_k127_17747_15 alpha beta alpha domain I K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 481.0
HKD1_k127_17747_16 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 464.0
HKD1_k127_17747_17 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 460.0
HKD1_k127_17747_18 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 451.0
HKD1_k127_17747_19 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 432.0
HKD1_k127_17747_2 Amidase - - - 6.038e-262 837.0
HKD1_k127_17747_20 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 408.0
HKD1_k127_17747_21 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 405.0
HKD1_k127_17747_22 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 396.0
HKD1_k127_17747_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 386.0
HKD1_k127_17747_24 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 387.0
HKD1_k127_17747_25 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 362.0
HKD1_k127_17747_26 nitrogen compound transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 353.0
HKD1_k127_17747_27 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 364.0
HKD1_k127_17747_28 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 333.0
HKD1_k127_17747_29 DnaJ molecular chaperone homology domain K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 325.0
HKD1_k127_17747_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.272e-217 692.0
HKD1_k127_17747_30 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 330.0
HKD1_k127_17747_31 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 337.0
HKD1_k127_17747_32 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 308.0
HKD1_k127_17747_33 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 313.0
HKD1_k127_17747_34 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 305.0
HKD1_k127_17747_35 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002029 291.0
HKD1_k127_17747_36 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001619 284.0
HKD1_k127_17747_37 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005333 282.0
HKD1_k127_17747_38 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000001317 262.0
HKD1_k127_17747_39 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001061 256.0
HKD1_k127_17747_4 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 9.459e-200 645.0
HKD1_k127_17747_40 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000001555 246.0
HKD1_k127_17747_41 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003128 272.0
HKD1_k127_17747_42 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000000000000000000000000000009603 244.0
HKD1_k127_17747_43 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000481 232.0
HKD1_k127_17747_44 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000003353 224.0
HKD1_k127_17747_45 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000002377 218.0
HKD1_k127_17747_46 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000431 209.0
HKD1_k127_17747_47 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.0000000000000000000000000000000000000000000000000000004477 203.0
HKD1_k127_17747_48 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000002878 190.0
HKD1_k127_17747_49 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000002516 177.0
HKD1_k127_17747_5 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 644.0
HKD1_k127_17747_50 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000001253 170.0
HKD1_k127_17747_51 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000005717 156.0
HKD1_k127_17747_52 thioesterase K07107 - - 0.0000000000000000000000000000000000000006128 151.0
HKD1_k127_17747_53 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000001843 158.0
HKD1_k127_17747_54 heat shock protein DnaJ K05516 - - 0.00000000000000000000000000000000000006266 149.0
HKD1_k127_17747_55 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000006881 137.0
HKD1_k127_17747_56 CoA-binding protein K06929 - - 0.000000000000000000000000000000001987 135.0
HKD1_k127_17747_57 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000001322 134.0
HKD1_k127_17747_58 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000009649 132.0
HKD1_k127_17747_59 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000001508 117.0
HKD1_k127_17747_6 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 621.0
HKD1_k127_17747_60 - - - - 0.000000000000000000000000000163 127.0
HKD1_k127_17747_61 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.0000000000000000000000000002477 122.0
HKD1_k127_17747_62 Zincin-like metallopeptidase - - - 0.000000000000000000000001838 109.0
HKD1_k127_17747_63 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000000000000000009156 112.0
HKD1_k127_17747_64 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000000000309 100.0
HKD1_k127_17747_65 metal-dependent protease of the PAD1 JAB1 superfamily K20110 - 3.4.19.15 0.0000000000000000000006816 100.0
HKD1_k127_17747_66 manually curated - - - 0.0000000000000000000189 98.0
HKD1_k127_17747_67 Surface antigen - - - 0.00000000000000000004338 105.0
HKD1_k127_17747_68 Chorismate mutase type II K04093 - 5.4.99.5 0.000000000000000001104 93.0
HKD1_k127_17747_69 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.000000000000000009535 85.0
HKD1_k127_17747_7 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 634.0
HKD1_k127_17747_70 phosphoribosylanthranilate isomerase activity K01817,K13501 GO:0000162,GO:0003674,GO:0003824,GO:0004640,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,4.1.3.27,5.3.1.24 0.0000000000000001121 94.0
HKD1_k127_17747_71 helix_turn_helix, Lux Regulon - - - 0.0000000000002421 76.0
HKD1_k127_17747_72 Pfam:N_methyl_2 - - - 0.000000000001816 76.0
HKD1_k127_17747_73 RNA-binding S4 domain protein K04762 - - 0.000000000009789 78.0
HKD1_k127_17747_74 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000002404 72.0
HKD1_k127_17747_75 Tetratricopeptide repeat - - - 0.000000001205 70.0
HKD1_k127_17747_76 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000007681 58.0
HKD1_k127_17747_77 - - - - 0.000007447 57.0
HKD1_k127_17747_78 - - - - 0.0006689 46.0
HKD1_k127_17747_8 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 606.0
HKD1_k127_17747_9 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 581.0
HKD1_k127_1803206_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1221.0
HKD1_k127_1803206_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1114.0
HKD1_k127_1803206_10 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 433.0
HKD1_k127_1803206_11 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 427.0
HKD1_k127_1803206_12 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 409.0
HKD1_k127_1803206_13 PFAM NAD-dependent epimerase dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 376.0
HKD1_k127_1803206_14 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 363.0
HKD1_k127_1803206_15 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 361.0
HKD1_k127_1803206_16 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 352.0
HKD1_k127_1803206_17 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 314.0
HKD1_k127_1803206_18 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 293.0
HKD1_k127_1803206_19 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002744 281.0
HKD1_k127_1803206_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114 1.17.1.4 8.879e-283 896.0
HKD1_k127_1803206_20 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004183 267.0
HKD1_k127_1803206_21 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000211 256.0
HKD1_k127_1803206_22 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000002364 240.0
HKD1_k127_1803206_23 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000004222 222.0
HKD1_k127_1803206_24 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000004577 192.0
HKD1_k127_1803206_25 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000001733 179.0
HKD1_k127_1803206_26 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000006726 162.0
HKD1_k127_1803206_27 domain protein K14194 - - 0.00000000000000000000000000000000000000000008496 183.0
HKD1_k127_1803206_28 C-terminal domain of histone - - - 0.000000000000000000000000000000000000000003658 161.0
HKD1_k127_1803206_29 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000004714 168.0
HKD1_k127_1803206_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 622.0
HKD1_k127_1803206_30 PFAM microcompartments protein K04027 - - 0.000000000000000000000000000000000000004641 147.0
HKD1_k127_1803206_31 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000005071 158.0
HKD1_k127_1803206_32 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000002872 142.0
HKD1_k127_1803206_33 Nodulation protein S (NodS) K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000001013 131.0
HKD1_k127_1803206_34 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000003974 128.0
HKD1_k127_1803206_35 Tetratricopeptide repeat - - - 0.00000000000000000000461 109.0
HKD1_k127_1803206_36 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000001297 89.0
HKD1_k127_1803206_37 - - - - 0.0000000000000001661 90.0
HKD1_k127_1803206_38 TIGRFAM Competence protein ComEA, helix-hairpin-helix K02237 - - 0.0000000000000128 84.0
HKD1_k127_1803206_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 584.0
HKD1_k127_1803206_40 Prokaryotic N-terminal methylation motif K08084 - - 0.0000000009404 66.0
HKD1_k127_1803206_42 ThiS family K03636 - - 0.00002766 52.0
HKD1_k127_1803206_43 arylsulfatase activity - - - 0.0001063 54.0
HKD1_k127_1803206_5 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 540.0
HKD1_k127_1803206_6 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 527.0
HKD1_k127_1803206_7 chelatase, subunit chli K06400,K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 526.0
HKD1_k127_1803206_8 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 514.0
HKD1_k127_1803206_9 TIGRFAM acetaldehyde dehydrogenase (acetylating) K00132 - 1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 495.0
HKD1_k127_183136_0 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 505.0
HKD1_k127_183136_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 411.0
HKD1_k127_183136_10 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000001945 199.0
HKD1_k127_183136_11 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000005195 185.0
HKD1_k127_183136_12 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000168 184.0
HKD1_k127_183136_13 PFAM Acetyltransferase (GNAT) family K18815 - 2.3.1.82 0.00000000000000000000000000000000000000000000000001684 185.0
HKD1_k127_183136_14 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000009018 146.0
HKD1_k127_183136_15 Protein of unknown function (DUF2834) - - - 0.00000000000000000000000000000001227 132.0
HKD1_k127_183136_16 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.000000000000000000000000000001231 137.0
HKD1_k127_183136_17 - - - - 0.000000000000000000000000001586 117.0
HKD1_k127_183136_18 - - - - 0.000000000000000001995 94.0
HKD1_k127_183136_19 DinB family - - - 0.000000000000005528 82.0
HKD1_k127_183136_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 361.0
HKD1_k127_183136_20 Aminotransferase class-V - - - 0.000000000000007633 81.0
HKD1_k127_183136_3 Phosphorylase superfamily K01243 - 3.2.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 295.0
HKD1_k127_183136_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001392 282.0
HKD1_k127_183136_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003085 284.0
HKD1_k127_183136_6 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001548 282.0
HKD1_k127_183136_7 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004549 250.0
HKD1_k127_183136_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003633 241.0
HKD1_k127_183136_9 - - - - 0.000000000000000000000000000000000000000000000000000001495 196.0
HKD1_k127_1972571_0 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 0.0 1070.0
HKD1_k127_1972571_1 Acetolactate synthase, large subunit K01652 - 2.2.1.6 1.956e-271 848.0
HKD1_k127_1972571_10 Cytochrome b(C-terminal)/b6/petD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 387.0
HKD1_k127_1972571_11 glycyl-tRNA synthetase, tetrameric type, beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 402.0
HKD1_k127_1972571_12 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 374.0
HKD1_k127_1972571_13 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 377.0
HKD1_k127_1972571_14 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 319.0
HKD1_k127_1972571_15 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 314.0
HKD1_k127_1972571_16 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001411 275.0
HKD1_k127_1972571_17 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000006926 223.0
HKD1_k127_1972571_18 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000006957 218.0
HKD1_k127_1972571_19 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000002047 209.0
HKD1_k127_1972571_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.415e-230 725.0
HKD1_k127_1972571_20 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000002162 202.0
HKD1_k127_1972571_21 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000001905 193.0
HKD1_k127_1972571_22 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000001085 186.0
HKD1_k127_1972571_23 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000004137 128.0
HKD1_k127_1972571_24 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000001856 113.0
HKD1_k127_1972571_26 HEAT repeats - - - 0.000000000000965 79.0
HKD1_k127_1972571_28 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0006389 51.0
HKD1_k127_1972571_3 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 612.0
HKD1_k127_1972571_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004668 603.0
HKD1_k127_1972571_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 485.0
HKD1_k127_1972571_6 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 455.0
HKD1_k127_1972571_7 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 453.0
HKD1_k127_1972571_8 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 458.0
HKD1_k127_1972571_9 PFAM Cytochrome b b6 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 426.0
HKD1_k127_2024021_0 Heavy metal translocating P-type atpase K01534 - 3.6.3.3,3.6.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 617.0
HKD1_k127_2024021_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 358.0
HKD1_k127_2024021_10 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000001396 142.0
HKD1_k127_2024021_11 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.00000000000000000000000000005161 120.0
HKD1_k127_2024021_12 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000005792 106.0
HKD1_k127_2024021_13 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000008147 61.0
HKD1_k127_2024021_15 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.000001244 59.0
HKD1_k127_2024021_16 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0001484 47.0
HKD1_k127_2024021_2 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 361.0
HKD1_k127_2024021_3 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 333.0
HKD1_k127_2024021_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 293.0
HKD1_k127_2024021_5 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002729 289.0
HKD1_k127_2024021_6 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002722 271.0
HKD1_k127_2024021_7 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001576 256.0
HKD1_k127_2024021_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000003139 166.0
HKD1_k127_2024021_9 Methyltransferase type 12 - - - 0.000000000000000000000000000000000768 141.0
HKD1_k127_2034674_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1380.0
HKD1_k127_2034674_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 520.0
HKD1_k127_2034674_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 514.0
HKD1_k127_2057877_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1362.0
HKD1_k127_2057877_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 4.66e-321 996.0
HKD1_k127_2071486_0 4Fe-4S dicluster domain K00184 - - 0.0 1114.0
HKD1_k127_2071486_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.643e-280 871.0
HKD1_k127_2071486_10 PFAM Alpha beta hydrolase K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 472.0
HKD1_k127_2071486_11 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 455.0
HKD1_k127_2071486_12 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 425.0
HKD1_k127_2071486_13 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 410.0
HKD1_k127_2071486_14 ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 413.0
HKD1_k127_2071486_15 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 407.0
HKD1_k127_2071486_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 392.0
HKD1_k127_2071486_17 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 382.0
HKD1_k127_2071486_18 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 348.0
HKD1_k127_2071486_19 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 347.0
HKD1_k127_2071486_2 Polysulphide reductase, NrfD K00185 - - 4.466e-220 689.0
HKD1_k127_2071486_20 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 343.0
HKD1_k127_2071486_21 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 325.0
HKD1_k127_2071486_22 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 341.0
HKD1_k127_2071486_23 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 311.0
HKD1_k127_2071486_24 Aldo/keto reductase family K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 315.0
HKD1_k127_2071486_25 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 306.0
HKD1_k127_2071486_26 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 301.0
HKD1_k127_2071486_27 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 294.0
HKD1_k127_2071486_28 Penicillin binding protein transpeptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005256 275.0
HKD1_k127_2071486_29 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000007586 266.0
HKD1_k127_2071486_3 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 604.0
HKD1_k127_2071486_30 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002725 257.0
HKD1_k127_2071486_31 COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000006529 264.0
HKD1_k127_2071486_32 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000799 252.0
HKD1_k127_2071486_33 glycerophosphodiester transmembrane transport K02026,K08715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004946 255.0
HKD1_k127_2071486_34 Bacterial regulatory helix-turn-helix protein, lysR family K03576 - - 0.00000000000000000000000000000000000000000000000000000000000000000009931 242.0
HKD1_k127_2071486_35 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000378 252.0
HKD1_k127_2071486_36 NADPH quinone reductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000001037 237.0
HKD1_k127_2071486_37 3-Demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000004903 203.0
HKD1_k127_2071486_38 Membrane - - - 0.000000000000000000000000000000000000000000000000000002815 212.0
HKD1_k127_2071486_39 glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000003851 199.0
HKD1_k127_2071486_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 579.0
HKD1_k127_2071486_40 Type II secretory pathway, component ExeA K02450 - - 0.00000000000000000000000000000000000000000000000001837 198.0
HKD1_k127_2071486_41 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000002905 197.0
HKD1_k127_2071486_42 YCII-related domain - - - 0.00000000000000000000000000000000000000000002468 163.0
HKD1_k127_2071486_43 transferase activity, transferring acyl groups K03824 - - 0.0000000000000000000000000000000000000000002907 164.0
HKD1_k127_2071486_44 YCII-related domain - - - 0.0000000000000000000000000000000000000000007591 163.0
HKD1_k127_2071486_45 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000001428 164.0
HKD1_k127_2071486_46 - - - - 0.0000000000000000000000000000000001013 152.0
HKD1_k127_2071486_47 - - - - 0.0000000000000000000000000000000009341 151.0
HKD1_k127_2071486_48 Thioredoxin domain - - - 0.00000000000000000000000000002626 122.0
HKD1_k127_2071486_49 Regulator of nitric oxide reductase transcription K19339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000007161 115.0
HKD1_k127_2071486_5 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 550.0
HKD1_k127_2071486_50 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000000002708 96.0
HKD1_k127_2071486_51 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000838 96.0
HKD1_k127_2071486_52 alkyl hydroperoxide reductase activity - - - 0.000000000000000002814 85.0
HKD1_k127_2071486_53 - - - - 0.000000000000000002822 94.0
HKD1_k127_2071486_55 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000002662 68.0
HKD1_k127_2071486_56 amine dehydrogenase activity - - - 0.000000006137 68.0
HKD1_k127_2071486_57 Regulator of nitric oxide reductase transcription K19339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000001295 61.0
HKD1_k127_2071486_6 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 540.0
HKD1_k127_2071486_7 Peptidase dimerisation domain K01439,K13049 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 513.0
HKD1_k127_2071486_8 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 504.0
HKD1_k127_2071486_9 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007337 505.0
HKD1_k127_2080628_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1450.0
HKD1_k127_2080628_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1320.0
HKD1_k127_2080628_10 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000001822 108.0
HKD1_k127_2080628_11 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008653,GO:0009279,GO:0009311,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0016788,GO:0019637,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0042802,GO:0042803,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044462,GO:0044464,GO:0046493,GO:0046983,GO:0050528,GO:0052689,GO:0071704,GO:0071944,GO:1901135,GO:1901269,GO:1903509 - 0.00000000000000000000004119 108.0
HKD1_k127_2080628_12 Dehydrogenase K00074 - 1.1.1.157 0.00000000001003 68.0
HKD1_k127_2080628_13 - - - - 0.000000005534 65.0
HKD1_k127_2080628_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 452.0
HKD1_k127_2080628_3 EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 346.0
HKD1_k127_2080628_4 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 347.0
HKD1_k127_2080628_5 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008365 256.0
HKD1_k127_2080628_6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001218 239.0
HKD1_k127_2080628_7 Protein of unknown function (DUF1345) - - - 0.000000000000000000000000000000000000000000001145 173.0
HKD1_k127_2080628_8 PFAM phosphate acetyl butaryl transferase K00625 - 2.3.1.8 0.000000000000000000000000000000002361 132.0
HKD1_k127_2080628_9 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.00000000000000000000000007758 119.0
HKD1_k127_2083401_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 4.35e-321 995.0
HKD1_k127_2083401_1 Spermine/spermidine synthase domain - - - 9.833e-285 895.0
HKD1_k127_2083401_10 Bacterial protein of unknown function (DUF885) - - - 1.23e-206 662.0
HKD1_k127_2083401_101 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000002062 136.0
HKD1_k127_2083401_102 peptidyl-tyrosine sulfation K13992 - - 0.00000000000000000000000000000001154 138.0
HKD1_k127_2083401_103 GrpB protein - - - 0.00000000000000000000000000000002116 143.0
HKD1_k127_2083401_104 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000007999 121.0
HKD1_k127_2083401_105 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000002186 123.0
HKD1_k127_2083401_106 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000002719 110.0
HKD1_k127_2083401_107 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000001285 111.0
HKD1_k127_2083401_108 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000002393 100.0
HKD1_k127_2083401_11 Cystathionine beta-synthase K01697 - 4.2.1.22 2.112e-203 646.0
HKD1_k127_2083401_110 - - - - 0.0000000000000000000003512 100.0
HKD1_k127_2083401_111 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000006552 96.0
HKD1_k127_2083401_112 Peptidase family M28 - - - 0.0000000000000000001535 105.0
HKD1_k127_2083401_113 Ribosomal protein L30p/L7e K02907 - - 0.00000000000004605 73.0
HKD1_k127_2083401_114 Yip1 domain - - - 0.00000000000127 77.0
HKD1_k127_2083401_115 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000006596 71.0
HKD1_k127_2083401_116 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000002386 69.0
HKD1_k127_2083401_117 Winged helix DNA-binding domain - - - 0.00000000003654 77.0
HKD1_k127_2083401_118 deoxyhypusine monooxygenase activity - - - 0.00000002414 62.0
HKD1_k127_2083401_119 Helix-turn-helix domain K15539 - - 0.00000002436 61.0
HKD1_k127_2083401_12 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 616.0
HKD1_k127_2083401_120 - - - - 0.00000006189 64.0
HKD1_k127_2083401_121 Glyoxalase-like domain - - - 0.0000002162 63.0
HKD1_k127_2083401_122 S23 ribosomal protein - - - 0.0000005238 58.0
HKD1_k127_2083401_123 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000005755 58.0
HKD1_k127_2083401_124 - - - - 0.0000008171 61.0
HKD1_k127_2083401_125 metallopeptidase activity K01179,K20276 - 3.2.1.4 0.000001358 55.0
HKD1_k127_2083401_126 helix_turn_helix multiple antibiotic resistance protein - - - 0.0003431 49.0
HKD1_k127_2083401_127 general secretion pathway protein K02650 - - 0.0008033 50.0
HKD1_k127_2083401_13 protein-containing complex disassembly K02837,K07133 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 600.0
HKD1_k127_2083401_14 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 576.0
HKD1_k127_2083401_15 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 571.0
HKD1_k127_2083401_16 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 541.0
HKD1_k127_2083401_17 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 528.0
HKD1_k127_2083401_18 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 515.0
HKD1_k127_2083401_19 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 513.0
HKD1_k127_2083401_2 Dehydrogenase K00117 - 1.1.5.2 4.458e-279 876.0
HKD1_k127_2083401_20 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 514.0
HKD1_k127_2083401_21 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 508.0
HKD1_k127_2083401_22 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 486.0
HKD1_k127_2083401_23 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 472.0
HKD1_k127_2083401_24 amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 470.0
HKD1_k127_2083401_25 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 490.0
HKD1_k127_2083401_26 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 471.0
HKD1_k127_2083401_27 peptidase activity K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 485.0
HKD1_k127_2083401_28 phosphorelay signal transduction system K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 479.0
HKD1_k127_2083401_29 tRNA wobble cytosine modification - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 452.0
HKD1_k127_2083401_3 PA domain K14647 GO:0005575,GO:0005576 - 1.977e-262 837.0
HKD1_k127_2083401_30 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 436.0
HKD1_k127_2083401_31 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 441.0
HKD1_k127_2083401_32 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 404.0
HKD1_k127_2083401_33 Binding-protein-dependent transport system inner membrane component K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 374.0
HKD1_k127_2083401_34 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 381.0
HKD1_k127_2083401_35 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 361.0
HKD1_k127_2083401_36 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 342.0
HKD1_k127_2083401_37 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 341.0
HKD1_k127_2083401_38 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 337.0
HKD1_k127_2083401_39 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 328.0
HKD1_k127_2083401_4 Elongation factor G, domain IV K02355 - - 1.69e-252 797.0
HKD1_k127_2083401_40 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 318.0
HKD1_k127_2083401_41 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 316.0
HKD1_k127_2083401_42 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 309.0
HKD1_k127_2083401_43 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 314.0
HKD1_k127_2083401_44 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 297.0
HKD1_k127_2083401_45 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 314.0
HKD1_k127_2083401_46 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 290.0
HKD1_k127_2083401_47 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 289.0
HKD1_k127_2083401_48 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 296.0
HKD1_k127_2083401_49 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008732 293.0
HKD1_k127_2083401_5 efflux transmembrane transporter activity - - - 3.236e-241 774.0
HKD1_k127_2083401_50 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001202 283.0
HKD1_k127_2083401_51 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000194 293.0
HKD1_k127_2083401_52 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02031,K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001089 282.0
HKD1_k127_2083401_53 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002035 278.0
HKD1_k127_2083401_54 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003938 282.0
HKD1_k127_2083401_55 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003561 280.0
HKD1_k127_2083401_56 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005998 270.0
HKD1_k127_2083401_57 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007411 265.0
HKD1_k127_2083401_58 tRNA synthetases class I (E and Q), catalytic domain K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001289 268.0
HKD1_k127_2083401_59 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005183 272.0
HKD1_k127_2083401_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.009e-231 728.0
HKD1_k127_2083401_60 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002477 267.0
HKD1_k127_2083401_61 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009189 270.0
HKD1_k127_2083401_62 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002451 245.0
HKD1_k127_2083401_63 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006751 252.0
HKD1_k127_2083401_64 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000005606 233.0
HKD1_k127_2083401_65 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000006949 225.0
HKD1_k127_2083401_66 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000018 250.0
HKD1_k127_2083401_67 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000006173 226.0
HKD1_k127_2083401_68 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000008306 223.0
HKD1_k127_2083401_69 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000002671 220.0
HKD1_k127_2083401_7 Putative modulator of DNA gyrase K03568 - - 7.726e-229 720.0
HKD1_k127_2083401_70 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000001264 222.0
HKD1_k127_2083401_71 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000004083 223.0
HKD1_k127_2083401_72 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000113 216.0
HKD1_k127_2083401_73 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000005704 208.0
HKD1_k127_2083401_74 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000006911 221.0
HKD1_k127_2083401_75 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000002458 223.0
HKD1_k127_2083401_76 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000002876 195.0
HKD1_k127_2083401_77 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000006023 188.0
HKD1_k127_2083401_78 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000004211 188.0
HKD1_k127_2083401_79 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000622 186.0
HKD1_k127_2083401_8 Amidase K01426 - 3.5.1.4 1.136e-224 715.0
HKD1_k127_2083401_80 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000001243 186.0
HKD1_k127_2083401_81 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000002196 195.0
HKD1_k127_2083401_82 PhoQ Sensor K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000002816 203.0
HKD1_k127_2083401_83 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000004289 183.0
HKD1_k127_2083401_84 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000005756 184.0
HKD1_k127_2083401_85 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000002021 189.0
HKD1_k127_2083401_86 - - - - 0.00000000000000000000000000000000000000000000000109 179.0
HKD1_k127_2083401_87 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000000001934 175.0
HKD1_k127_2083401_88 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000007359 164.0
HKD1_k127_2083401_89 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000007359 164.0
HKD1_k127_2083401_9 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.494e-222 704.0
HKD1_k127_2083401_90 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000001291 162.0
HKD1_k127_2083401_91 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000002168 156.0
HKD1_k127_2083401_92 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000008962 166.0
HKD1_k127_2083401_93 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000003244 156.0
HKD1_k127_2083401_94 - - - - 0.000000000000000000000000000000000000001451 171.0
HKD1_k127_2083401_95 Transcription factor zinc-finger - - - 0.000000000000000000000000000000000000005697 156.0
HKD1_k127_2083401_96 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000005483 147.0
HKD1_k127_2083401_97 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000002586 141.0
HKD1_k127_2083401_98 Serine/threonine phosphatases, family 2C, catalytic domain K01090 - 3.1.3.16 0.00000000000000000000000000000000003531 144.0
HKD1_k127_2083401_99 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000001391 131.0
HKD1_k127_2138327_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1359.0
HKD1_k127_2138327_1 amino acid - - - 5.802e-307 952.0
HKD1_k127_2138327_10 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 610.0
HKD1_k127_2138327_11 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 583.0
HKD1_k127_2138327_12 Mo-co oxidoreductase dimerisation domain K17225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 533.0
HKD1_k127_2138327_13 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 541.0
HKD1_k127_2138327_14 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 537.0
HKD1_k127_2138327_15 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 509.0
HKD1_k127_2138327_16 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 479.0
HKD1_k127_2138327_17 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 471.0
HKD1_k127_2138327_18 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 458.0
HKD1_k127_2138327_19 Common central domain of tyrosinase K00505 - 1.14.18.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 425.0
HKD1_k127_2138327_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 6.508e-288 892.0
HKD1_k127_2138327_20 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 415.0
HKD1_k127_2138327_21 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 411.0
HKD1_k127_2138327_22 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 418.0
HKD1_k127_2138327_23 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 391.0
HKD1_k127_2138327_24 Elongator protein 3, MiaB family, Radical SAM K22226,K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 379.0
HKD1_k127_2138327_25 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 378.0
HKD1_k127_2138327_26 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 389.0
HKD1_k127_2138327_27 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 381.0
HKD1_k127_2138327_28 COG2015, Alkyl sulfatase and related hydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 380.0
HKD1_k127_2138327_29 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 359.0
HKD1_k127_2138327_3 PFAM HypF finger K04656 - - 7.581e-274 862.0
HKD1_k127_2138327_30 HlyD family secretion protein K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 340.0
HKD1_k127_2138327_31 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 337.0
HKD1_k127_2138327_32 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 317.0
HKD1_k127_2138327_33 symporter activity K03307,K14392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 320.0
HKD1_k127_2138327_34 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 320.0
HKD1_k127_2138327_35 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 327.0
HKD1_k127_2138327_36 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009308 295.0
HKD1_k127_2138327_37 PFAM Ornithine cyclodeaminase mu-crystallin K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 299.0
HKD1_k127_2138327_38 succinylglutamate desuccinylase aspartoacylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 292.0
HKD1_k127_2138327_39 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002457 279.0
HKD1_k127_2138327_4 secondary active sulfate transmembrane transporter activity K03321 - - 5.372e-268 836.0
HKD1_k127_2138327_40 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000831 280.0
HKD1_k127_2138327_41 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009123 279.0
HKD1_k127_2138327_42 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006125 258.0
HKD1_k127_2138327_43 MerR, DNA binding K13639 - - 0.000000000000000000000000000000000000000000000000000000000000000000004168 236.0
HKD1_k127_2138327_44 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000003094 250.0
HKD1_k127_2138327_45 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002503 234.0
HKD1_k127_2138327_46 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000001907 230.0
HKD1_k127_2138327_47 helix_turn_helix, Lux Regulon K07684 - - 0.0000000000000000000000000000000000000000000000000000000000002514 219.0
HKD1_k127_2138327_48 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000002528 217.0
HKD1_k127_2138327_49 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000000000000000000002712 213.0
HKD1_k127_2138327_5 Nickel-dependent hydrogenase K06281 - 1.12.99.6 2.672e-263 832.0
HKD1_k127_2138327_50 protein histidine kinase activity K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000379 229.0
HKD1_k127_2138327_51 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000003714 217.0
HKD1_k127_2138327_52 - - - - 0.000000000000000000000000000000000000000000000000000006187 210.0
HKD1_k127_2138327_53 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.0000000000000000000000000000000000000000000000003985 183.0
HKD1_k127_2138327_54 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000005804 187.0
HKD1_k127_2138327_55 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000000000000009056 180.0
HKD1_k127_2138327_56 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000002553 176.0
HKD1_k127_2138327_57 - - - - 0.00000000000000000000000000000000000000000001271 168.0
HKD1_k127_2138327_58 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000735 167.0
HKD1_k127_2138327_59 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000003669 165.0
HKD1_k127_2138327_6 N-acetyldiaminopimelate deacetylase activity K12941 - - 1.32e-239 751.0
HKD1_k127_2138327_60 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000000000000000000000000000000000009026 147.0
HKD1_k127_2138327_61 Low molecular weight phosphotyrosine protein phosphatase - - - 0.00000000000000000000000000000000000001978 149.0
HKD1_k127_2138327_62 - - - - 0.00000000000000000000000000000000000005771 149.0
HKD1_k127_2138327_64 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000000000000002259 148.0
HKD1_k127_2138327_65 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000001359 140.0
HKD1_k127_2138327_66 PFAM Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain - - - 0.0000000000000000000000000000000001103 149.0
HKD1_k127_2138327_67 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000002333 140.0
HKD1_k127_2138327_68 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.0000000000000000000000000000001579 132.0
HKD1_k127_2138327_69 - - - - 0.0000000000000000000000000000003232 125.0
HKD1_k127_2138327_7 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 1.549e-236 767.0
HKD1_k127_2138327_70 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000006658 121.0
HKD1_k127_2138327_71 - - - - 0.00000000000000000000000000005965 120.0
HKD1_k127_2138327_72 carbon dioxide binding K04653 - - 0.0000000000000000000000000002969 117.0
HKD1_k127_2138327_73 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000001139 113.0
HKD1_k127_2138327_74 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420,K10914 - - 0.0000000000000000000000000456 119.0
HKD1_k127_2138327_75 DNA-binding transcription factor activity - - - 0.000000000000000000000006605 106.0
HKD1_k127_2138327_77 SdrD B-like domain - - - 0.00000000000000000007583 102.0
HKD1_k127_2138327_78 Predicted membrane protein (DUF2127) - - - 0.00000000000000005932 87.0
HKD1_k127_2138327_79 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000001108 81.0
HKD1_k127_2138327_8 COGs COG0737 5'-nucleotidase 2' 3'-cyclic phosphodiesterase and related esterase K01081,K11751 - 3.1.3.5,3.6.1.45 7.716e-214 677.0
HKD1_k127_2138327_80 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000001697 81.0
HKD1_k127_2138327_81 permease K07243 - - 0.00000000000001982 79.0
HKD1_k127_2138327_82 - - - - 0.0000000000001623 79.0
HKD1_k127_2138327_83 - - - - 0.0000000001515 66.0
HKD1_k127_2138327_84 - - - - 0.00000000214 66.0
HKD1_k127_2138327_85 Outer membrane efflux protein - - - 0.000000003912 70.0
HKD1_k127_2138327_86 - - - - 0.000003246 57.0
HKD1_k127_2138327_88 Domain of unknown function (DUF4382) - - - 0.00003207 54.0
HKD1_k127_2138327_89 Peptidase family M28 - - - 0.0000762 57.0
HKD1_k127_2138327_9 Cyclic nucleotide-monophosphate binding domain - - - 3.564e-194 619.0
HKD1_k127_2158185_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.231e-278 877.0
HKD1_k127_2158185_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 603.0
HKD1_k127_2158185_10 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 359.0
HKD1_k127_2158185_11 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 352.0
HKD1_k127_2158185_12 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 329.0
HKD1_k127_2158185_13 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 311.0
HKD1_k127_2158185_14 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 312.0
HKD1_k127_2158185_15 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000305 297.0
HKD1_k127_2158185_16 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007968 280.0
HKD1_k127_2158185_17 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000001816 241.0
HKD1_k127_2158185_18 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000007412 158.0
HKD1_k127_2158185_19 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000001899 162.0
HKD1_k127_2158185_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 534.0
HKD1_k127_2158185_20 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000000001094 130.0
HKD1_k127_2158185_21 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000003456 99.0
HKD1_k127_2158185_22 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000004061 97.0
HKD1_k127_2158185_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 505.0
HKD1_k127_2158185_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 484.0
HKD1_k127_2158185_5 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 480.0
HKD1_k127_2158185_6 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 454.0
HKD1_k127_2158185_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 427.0
HKD1_k127_2158185_8 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 410.0
HKD1_k127_2158185_9 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 404.0
HKD1_k127_2173965_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0 2166.0
HKD1_k127_2173965_1 DEAD DEAH box helicase K03724 - - 0.0 1501.0
HKD1_k127_2173965_10 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009762 496.0
HKD1_k127_2173965_11 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 489.0
HKD1_k127_2173965_12 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 485.0
HKD1_k127_2173965_13 Serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 462.0
HKD1_k127_2173965_14 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 448.0
HKD1_k127_2173965_15 Major facilitator Superfamily K08178 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 442.0
HKD1_k127_2173965_16 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 449.0
HKD1_k127_2173965_17 RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 447.0
HKD1_k127_2173965_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 405.0
HKD1_k127_2173965_19 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 393.0
HKD1_k127_2173965_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1365.0
HKD1_k127_2173965_20 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 394.0
HKD1_k127_2173965_21 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 379.0
HKD1_k127_2173965_22 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 353.0
HKD1_k127_2173965_23 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 351.0
HKD1_k127_2173965_24 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 334.0
HKD1_k127_2173965_25 PFAM Glutamine cyclotransferase K00683 - 2.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 313.0
HKD1_k127_2173965_26 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 328.0
HKD1_k127_2173965_27 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 321.0
HKD1_k127_2173965_28 MFS_1 like family K08151,K08153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 295.0
HKD1_k127_2173965_29 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001357 270.0
HKD1_k127_2173965_3 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.0 1068.0
HKD1_k127_2173965_30 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002109 260.0
HKD1_k127_2173965_31 oxidoreductase activity, acting on CH-OH group of donors K13237 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000001963 262.0
HKD1_k127_2173965_32 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004764 255.0
HKD1_k127_2173965_33 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001192 262.0
HKD1_k127_2173965_34 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000001355 230.0
HKD1_k127_2173965_35 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000002721 229.0
HKD1_k127_2173965_36 Biotin-lipoyl like K01993 - - 0.000000000000000000000000000000000000000000000000000324 198.0
HKD1_k127_2173965_37 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.000000000000000000000000000000000000000000000000003079 198.0
HKD1_k127_2173965_38 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000001412 198.0
HKD1_k127_2173965_39 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000001079 178.0
HKD1_k127_2173965_4 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 3.157e-310 970.0
HKD1_k127_2173965_40 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000002124 171.0
HKD1_k127_2173965_41 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000003279 170.0
HKD1_k127_2173965_42 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000000001416 162.0
HKD1_k127_2173965_43 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000002062 160.0
HKD1_k127_2173965_44 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000003641 158.0
HKD1_k127_2173965_45 Transcriptional regulator - - - 0.0000000000000000000000000000000005468 149.0
HKD1_k127_2173965_46 photoreceptor activity K07315,K08744,K20971 - 2.7.8.41,3.1.3.3 0.000000000000000000000000000000006499 142.0
HKD1_k127_2173965_47 thiolester hydrolase activity K06889 - - 0.000000000000000000000000001777 124.0
HKD1_k127_2173965_48 cheY-homologous receiver domain - - - 0.0000000000000000000000000211 112.0
HKD1_k127_2173965_49 Histidine kinase internal region K02478 - 2.7.13.3 0.00000000000000000000000008047 109.0
HKD1_k127_2173965_5 Dehydrogenase K00117 - 1.1.5.2 6.234e-292 913.0
HKD1_k127_2173965_50 thiolester hydrolase activity K06889 - - 0.00000000000000000001922 105.0
HKD1_k127_2173965_51 RNA recognition motif - - - 0.0000000000000000001013 96.0
HKD1_k127_2173965_52 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.0000000000000000002613 104.0
HKD1_k127_2173965_53 response regulator - - - 0.00000000000000003428 94.0
HKD1_k127_2173965_54 - - - - 0.000000000000006638 75.0
HKD1_k127_2173965_55 oxidoreductase activity - - - 0.000000000000008356 89.0
HKD1_k127_2173965_56 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000211 71.0
HKD1_k127_2173965_57 Helix-turn-helix domain K15539 - - 0.0000000003503 67.0
HKD1_k127_2173965_58 - - - - 0.000000002036 61.0
HKD1_k127_2173965_59 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000003982 61.0
HKD1_k127_2173965_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 9.105e-231 730.0
HKD1_k127_2173965_60 - - - - 0.000009038 57.0
HKD1_k127_2173965_61 Prenyltransferase K13277 - - 0.00004347 55.0
HKD1_k127_2173965_62 PFAM von Willebrand factor type A K07114 - - 0.00008318 53.0
HKD1_k127_2173965_63 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0003695 46.0
HKD1_k127_2173965_64 CHRD domain - - - 0.0006926 49.0
HKD1_k127_2173965_66 YtxH-like protein - - - 0.000952 47.0
HKD1_k127_2173965_7 oligopeptide transporter, OPT family - - - 3.336e-201 645.0
HKD1_k127_2173965_8 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 568.0
HKD1_k127_2173965_9 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 536.0
HKD1_k127_2214426_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.398e-244 769.0
HKD1_k127_2214426_1 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 5.26e-223 707.0
HKD1_k127_2214426_10 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 319.0
HKD1_k127_2214426_11 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001724 272.0
HKD1_k127_2214426_12 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002617 254.0
HKD1_k127_2214426_13 ABC 3 transport family K09819,K11606,K11708,K11709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008495 250.0
HKD1_k127_2214426_14 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002115 248.0
HKD1_k127_2214426_15 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000000000002302 163.0
HKD1_k127_2214426_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000006176 152.0
HKD1_k127_2214426_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000001068 143.0
HKD1_k127_2214426_18 RNA recognition motif - - - 0.000000000000000000000000004672 113.0
HKD1_k127_2214426_19 CoA binding domain K06929 - - 0.00000000000000000000001465 108.0
HKD1_k127_2214426_2 Phosphate acyltransferases K01897 - 6.2.1.3 7.917e-223 721.0
HKD1_k127_2214426_20 Protein of unknown function (DUF504) - - - 0.000000000000000000001659 97.0
HKD1_k127_2214426_21 translation release factor activity K03265 - - 0.000000000000001695 89.0
HKD1_k127_2214426_22 - - - - 0.0000136 50.0
HKD1_k127_2214426_3 efflux transmembrane transporter activity - - - 1.696e-220 711.0
HKD1_k127_2214426_4 DNA polymerase beta thumb K02347 - - 2.714e-218 691.0
HKD1_k127_2214426_5 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 606.0
HKD1_k127_2214426_6 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009002 606.0
HKD1_k127_2214426_7 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 460.0
HKD1_k127_2214426_8 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 343.0
HKD1_k127_2214426_9 RNA-3'-phosphate cyclase activity K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 333.0
HKD1_k127_2259345_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1172.0
HKD1_k127_2259345_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 459.0
HKD1_k127_2259345_10 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000004936 220.0
HKD1_k127_2259345_11 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000002543 227.0
HKD1_k127_2259345_12 Male sterility protein K15891 - 1.1.1.354 0.000000000000000000000000000000000000000000000000000733 195.0
HKD1_k127_2259345_13 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000209 170.0
HKD1_k127_2259345_14 PFAM Organic solvent tolerance protein K04744 - - 0.000000000000000000000000000000000000000000005077 187.0
HKD1_k127_2259345_15 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000007222 166.0
HKD1_k127_2259345_16 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000001245 137.0
HKD1_k127_2259345_17 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.0000000000000000000000000004521 130.0
HKD1_k127_2259345_18 PFAM UbiA prenyltransferase K09833 GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009987,GO:0010189,GO:0018130,GO:0042360,GO:0042362,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617 2.5.1.115,2.5.1.116 0.00000000000000000005382 103.0
HKD1_k127_2259345_19 Preprotein translocase subunit K03210 - - 0.0000000000001058 75.0
HKD1_k127_2259345_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 436.0
HKD1_k127_2259345_3 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 408.0
HKD1_k127_2259345_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 407.0
HKD1_k127_2259345_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 346.0
HKD1_k127_2259345_6 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000827 281.0
HKD1_k127_2259345_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000004289 244.0
HKD1_k127_2259345_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000005019 240.0
HKD1_k127_2259345_9 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000001333 229.0
HKD1_k127_2279302_0 cellulose binding - - - 0.0 1270.0
HKD1_k127_2279302_1 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.0 1027.0
HKD1_k127_2279302_10 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001359 270.0
HKD1_k127_2279302_11 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009519 264.0
HKD1_k127_2279302_12 ubiquinone menaquinone biosynthesis methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001625 218.0
HKD1_k127_2279302_13 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000001934 207.0
HKD1_k127_2279302_14 - - - - 0.00000000000000000000000000000000000000000000000000000001116 199.0
HKD1_k127_2279302_15 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000008375 194.0
HKD1_k127_2279302_16 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000509 199.0
HKD1_k127_2279302_17 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000009164 172.0
HKD1_k127_2279302_18 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000001065 152.0
HKD1_k127_2279302_19 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000001123 159.0
HKD1_k127_2279302_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 618.0
HKD1_k127_2279302_20 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000001255 136.0
HKD1_k127_2279302_21 PFAM CoA-binding domain protein K06929 - - 0.000000000000000000000000000009136 121.0
HKD1_k127_2279302_22 MacB-like periplasmic core domain - - - 0.000000000000000000000000000101 121.0
HKD1_k127_2279302_23 TIGRFAM periplasmic serine protease, Do DeqQ family K04771 - 3.4.21.107 0.00000000000000000000005835 115.0
HKD1_k127_2279302_24 Haem-binding domain - - - 0.000000000000000008598 94.0
HKD1_k127_2279302_25 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000002467 74.0
HKD1_k127_2279302_26 dihydroorotate dehydrogenase activity - - - 0.0000003042 58.0
HKD1_k127_2279302_27 SnoaL-like domain - - - 0.0002646 50.0
HKD1_k127_2279302_3 Dehydrogenase K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 589.0
HKD1_k127_2279302_4 Copper amine oxidase, N3 domain K00276 - 1.4.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 542.0
HKD1_k127_2279302_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 502.0
HKD1_k127_2279302_6 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 505.0
HKD1_k127_2279302_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 430.0
HKD1_k127_2279302_8 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 410.0
HKD1_k127_2279302_9 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003044 273.0
HKD1_k127_2306557_0 Amidohydrolase family - - - 0.0 1107.0
HKD1_k127_2306557_1 Amidohydrolase family - - - 5.279e-269 871.0
HKD1_k127_2306557_10 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 353.0
HKD1_k127_2306557_11 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 335.0
HKD1_k127_2306557_12 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 348.0
HKD1_k127_2306557_13 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 339.0
HKD1_k127_2306557_14 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 339.0
HKD1_k127_2306557_15 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 309.0
HKD1_k127_2306557_16 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 302.0
HKD1_k127_2306557_17 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000007303 262.0
HKD1_k127_2306557_18 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002975 258.0
HKD1_k127_2306557_19 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001826 255.0
HKD1_k127_2306557_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 7.575e-236 753.0
HKD1_k127_2306557_20 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000006242 248.0
HKD1_k127_2306557_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001533 223.0
HKD1_k127_2306557_22 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000005286 217.0
HKD1_k127_2306557_23 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000000000000000000000139 211.0
HKD1_k127_2306557_24 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000006379 196.0
HKD1_k127_2306557_25 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000000000004911 161.0
HKD1_k127_2306557_26 von Willebrand factor, type A K07114 - - 0.00000000000000000000000004667 119.0
HKD1_k127_2306557_27 Frataxin-like domain K06202 - - 0.00000000000000000000003422 102.0
HKD1_k127_2306557_28 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000001108 82.0
HKD1_k127_2306557_29 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0000000000000183 78.0
HKD1_k127_2306557_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 540.0
HKD1_k127_2306557_30 - - - - 0.000004244 53.0
HKD1_k127_2306557_31 PFAM PKD domain containing protein - - - 0.000006199 58.0
HKD1_k127_2306557_32 Mitochondrial outer membrane protein iml2 - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0006950,GO:0008150,GO:0009987,GO:0010033,GO:0016020,GO:0019867,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070887,GO:0071218,GO:0071310,GO:0098588,GO:0098805 - 0.00006907 55.0
HKD1_k127_2306557_33 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.00009621 53.0
HKD1_k127_2306557_34 Alternative locus ID - - - 0.0004736 52.0
HKD1_k127_2306557_35 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0006272 51.0
HKD1_k127_2306557_4 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 529.0
HKD1_k127_2306557_5 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 471.0
HKD1_k127_2306557_6 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 469.0
HKD1_k127_2306557_7 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 375.0
HKD1_k127_2306557_8 Belongs to the proline racemase family K01777 - 5.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 359.0
HKD1_k127_2306557_9 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 371.0
HKD1_k127_2322901_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.231e-200 642.0
HKD1_k127_2322901_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 400.0
HKD1_k127_2322901_2 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002337 239.0
HKD1_k127_2322901_3 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000003044 114.0
HKD1_k127_2322901_4 Tripartite tricarboxylate transporter family receptor - - - 0.000005206 49.0
HKD1_k127_235334_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 1.268e-253 794.0
HKD1_k127_235334_1 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 4.73e-237 754.0
HKD1_k127_235334_10 flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 483.0
HKD1_k127_235334_11 GMC oxidoreductase K06151 - 1.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 463.0
HKD1_k127_235334_12 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 465.0
HKD1_k127_235334_13 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 421.0
HKD1_k127_235334_14 Domain of unknown function (DUF4178) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 422.0
HKD1_k127_235334_15 Amidase K01426,K21801 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 419.0
HKD1_k127_235334_16 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 393.0
HKD1_k127_235334_17 HMGL-like K01640 GO:0003674,GO:0003824,GO:0004419,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 350.0
HKD1_k127_235334_18 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 349.0
HKD1_k127_235334_19 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 334.0
HKD1_k127_235334_2 PFAM amidohydrolase - - - 4.428e-229 723.0
HKD1_k127_235334_20 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 271.0
HKD1_k127_235334_21 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000000000000000000000000000000000000000000000000000000000000000000003943 255.0
HKD1_k127_235334_22 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000005022 244.0
HKD1_k127_235334_23 Histidine kinase K01120,K07315 - 3.1.3.3,3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000005668 255.0
HKD1_k127_235334_24 PFAM Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000007539 233.0
HKD1_k127_235334_25 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000005573 215.0
HKD1_k127_235334_26 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.000000000000000000000000000000000000000000000000000005197 201.0
HKD1_k127_235334_27 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000002622 201.0
HKD1_k127_235334_28 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000003593 172.0
HKD1_k127_235334_29 S-adenosylmethionine decarboxylase K01611 - 4.1.1.50 0.00000000000000000000000000000000000000003414 155.0
HKD1_k127_235334_3 Dehydrogenase K00117 - 1.1.5.2 4.709e-227 721.0
HKD1_k127_235334_30 PFAM PemK family protein K07171 - - 0.000000000000000000000000000000000000000609 151.0
HKD1_k127_235334_31 - - - - 0.0000000000000000000000000000000000003327 149.0
HKD1_k127_235334_32 Protein of unknown function (DUF1698) - - - 0.000000000000000000000000000000000001487 156.0
HKD1_k127_235334_33 glucose sorbosone - - - 0.00000000000000000000000000000000004384 154.0
HKD1_k127_235334_34 - - - - 0.00000000000000000000000001824 126.0
HKD1_k127_235334_35 - - - - 0.00000000000000000000000004737 116.0
HKD1_k127_235334_37 Virulence factor BrkB - - - 0.0000000000000000000001336 109.0
HKD1_k127_235334_38 Gluconate 2-dehydrogenase K06152 - 1.1.99.3 0.0000000000000000000005134 105.0
HKD1_k127_235334_39 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000223 102.0
HKD1_k127_235334_4 Spermine/spermidine synthase domain K00797 - 2.5.1.16 3.226e-213 678.0
HKD1_k127_235334_40 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000001052 107.0
HKD1_k127_235334_41 Domain of Unknown Function (DUF350) - - - 0.00000000000000000002414 94.0
HKD1_k127_235334_42 SpoVT / AbrB like domain K07172 - - 0.0000000000000000002793 90.0
HKD1_k127_235334_43 Glycosyltransferase family 87 - - - 0.000000000000000004899 96.0
HKD1_k127_235334_44 - - - - 0.0000000000000005846 79.0
HKD1_k127_235334_45 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000002901 87.0
HKD1_k127_235334_46 Ankyrin repeat - - - 0.00000000006962 76.0
HKD1_k127_235334_47 Pfam:N_methyl_2 - - - 0.000000003924 65.0
HKD1_k127_235334_49 Protein of unknown function (DUF983) - - - 0.0000008127 56.0
HKD1_k127_235334_5 Protein of unknown function, DUF255 K06888 - - 4.774e-212 690.0
HKD1_k127_235334_50 pyridoxamine 5-phosphate - - - 0.00005363 51.0
HKD1_k127_235334_51 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0001348 55.0
HKD1_k127_235334_52 Part of a membrane complex involved in electron transport K03616 - - 0.0002089 49.0
HKD1_k127_235334_6 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 613.0
HKD1_k127_235334_7 proline dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 594.0
HKD1_k127_235334_8 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 571.0
HKD1_k127_235334_9 CoA carboxylase activity K01968 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 515.0
HKD1_k127_2372664_0 pyruvate dehydrogenase (acetyl-transferring) activity K00163 - 1.2.4.1 0.0 1324.0
HKD1_k127_2372664_1 Carboxypeptidase regulatory-like domain - - - 0.0 1170.0
HKD1_k127_2372664_10 amino acid K03294 - - 1.243e-204 648.0
HKD1_k127_2372664_11 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 1.477e-196 632.0
HKD1_k127_2372664_12 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019464,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045250,GO:0045252,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 616.0
HKD1_k127_2372664_13 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 610.0
HKD1_k127_2372664_14 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 588.0
HKD1_k127_2372664_15 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 555.0
HKD1_k127_2372664_16 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 514.0
HKD1_k127_2372664_17 S-acyltransferase activity K00627 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 488.0
HKD1_k127_2372664_18 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 490.0
HKD1_k127_2372664_19 PFAM Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 481.0
HKD1_k127_2372664_2 PFAM Radical SAM - - - 0.0 1125.0
HKD1_k127_2372664_20 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 428.0
HKD1_k127_2372664_21 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 422.0
HKD1_k127_2372664_22 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 400.0
HKD1_k127_2372664_23 Dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 404.0
HKD1_k127_2372664_24 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 385.0
HKD1_k127_2372664_25 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 385.0
HKD1_k127_2372664_26 Arsenical pump membrane protein K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 364.0
HKD1_k127_2372664_27 imidazolonepropionase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 356.0
HKD1_k127_2372664_28 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 333.0
HKD1_k127_2372664_29 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 341.0
HKD1_k127_2372664_3 MacB-like periplasmic core domain - - - 4.276e-262 837.0
HKD1_k127_2372664_30 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 338.0
HKD1_k127_2372664_31 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 329.0
HKD1_k127_2372664_32 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 332.0
HKD1_k127_2372664_33 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 311.0
HKD1_k127_2372664_34 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 307.0
HKD1_k127_2372664_35 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 319.0
HKD1_k127_2372664_36 gtp cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000008566 264.0
HKD1_k127_2372664_37 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001826 270.0
HKD1_k127_2372664_38 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008943 261.0
HKD1_k127_2372664_39 serine-type peptidase activity - GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019586,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046397,GO:0071704,GO:0072329,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000001437 265.0
HKD1_k127_2372664_4 Carboxypeptidase regulatory-like domain - - - 2.562e-256 825.0
HKD1_k127_2372664_40 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000001174 239.0
HKD1_k127_2372664_41 phosphorelay signal transduction system K02477,K07705,K21696 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000002153 241.0
HKD1_k127_2372664_42 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000005216 243.0
HKD1_k127_2372664_43 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000002007 211.0
HKD1_k127_2372664_44 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000003108 223.0
HKD1_k127_2372664_45 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000009463 218.0
HKD1_k127_2372664_46 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000002216 207.0
HKD1_k127_2372664_47 Domain of unknown function (DUF4281) - - - 0.000000000000000000000000000000000000000001815 159.0
HKD1_k127_2372664_48 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.0000000000000000000000000000000000000001348 161.0
HKD1_k127_2372664_49 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000001954 154.0
HKD1_k127_2372664_5 Prolyl oligopeptidase family - - - 2.47e-250 793.0
HKD1_k127_2372664_50 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000003189 153.0
HKD1_k127_2372664_51 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000004769 153.0
HKD1_k127_2372664_52 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000005148 149.0
HKD1_k127_2372664_53 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000107 158.0
HKD1_k127_2372664_54 WHG domain - - - 0.0000000000000000000000000000000001399 141.0
HKD1_k127_2372664_55 NUDIX domain - - - 0.0000000000000000000000000000000003256 143.0
HKD1_k127_2372664_56 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000003617 136.0
HKD1_k127_2372664_57 - - - - 0.0000000000000000000000000000004577 137.0
HKD1_k127_2372664_58 - - - - 0.00000000000000000000000000003316 123.0
HKD1_k127_2372664_59 Putative adhesin - - - 0.00000000000000000000000000006068 130.0
HKD1_k127_2372664_6 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 2.575e-232 728.0
HKD1_k127_2372664_60 oxidation-reduction process - - - 0.000000000000000000000000001134 119.0
HKD1_k127_2372664_61 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000003782 116.0
HKD1_k127_2372664_63 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.000000000000000002529 88.0
HKD1_k127_2372664_64 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000939 86.0
HKD1_k127_2372664_65 PBS lyase HEAT-like repeat - - - 0.000000000000006643 89.0
HKD1_k127_2372664_66 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000009541 80.0
HKD1_k127_2372664_67 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.00000000000001408 83.0
HKD1_k127_2372664_68 system-associated acyl-CoA thioesterase K07107 - - 0.0000000000001015 77.0
HKD1_k127_2372664_69 - - - - 0.000000000001577 79.0
HKD1_k127_2372664_7 PFAM peptidase M13 K01415 - 3.4.24.71 5.002e-226 719.0
HKD1_k127_2372664_70 - - - - 0.0000000002748 70.0
HKD1_k127_2372664_71 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.000004869 49.0
HKD1_k127_2372664_72 Histidine Phosphotransfer domain K11527 - 2.7.13.3 0.00007058 50.0
HKD1_k127_2372664_73 - - - - 0.0001625 53.0
HKD1_k127_2372664_8 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 1.392e-218 690.0
HKD1_k127_2372664_9 benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.898e-211 667.0
HKD1_k127_2380691_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.324e-318 996.0
HKD1_k127_2380691_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.868e-282 892.0
HKD1_k127_2380691_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 420.0
HKD1_k127_2380691_11 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 372.0
HKD1_k127_2380691_12 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 362.0
HKD1_k127_2380691_13 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 356.0
HKD1_k127_2380691_14 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 312.0
HKD1_k127_2380691_15 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 310.0
HKD1_k127_2380691_16 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 299.0
HKD1_k127_2380691_17 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001404 282.0
HKD1_k127_2380691_18 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003431 265.0
HKD1_k127_2380691_19 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003799 250.0
HKD1_k127_2380691_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.903e-255 799.0
HKD1_k127_2380691_20 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000003223 243.0
HKD1_k127_2380691_21 Regulatory protein, FmdB - - - 0.000000000000000000000000292 109.0
HKD1_k127_2380691_22 - - - - 0.0000000000000000000000003781 113.0
HKD1_k127_2380691_23 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000009195 111.0
HKD1_k127_2380691_24 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000005847 97.0
HKD1_k127_2380691_25 R3H domain protein K06346 - - 0.00000000000000000002159 97.0
HKD1_k127_2380691_26 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000005129 89.0
HKD1_k127_2380691_27 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000001762 81.0
HKD1_k127_2380691_28 Tetratricopeptide repeat - - - 0.000000000000008397 83.0
HKD1_k127_2380691_29 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000718 69.0
HKD1_k127_2380691_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.753e-232 728.0
HKD1_k127_2380691_4 PFAM UvrD REP helicase K03657 - 3.6.4.12 2.659e-198 644.0
HKD1_k127_2380691_5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 4.273e-195 641.0
HKD1_k127_2380691_6 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 560.0
HKD1_k127_2380691_7 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 497.0
HKD1_k127_2380691_8 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 494.0
HKD1_k127_2380691_9 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528,K16203 GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 443.0
HKD1_k127_2484362_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 6.185e-280 903.0
HKD1_k127_2484362_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.029e-227 717.0
HKD1_k127_2484362_10 antitermination protein NusG K05785 - - 0.0000000000000000000000000000009542 138.0
HKD1_k127_2484362_11 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000003025 127.0
HKD1_k127_2484362_12 - - - - 0.0000000000000000000003102 104.0
HKD1_k127_2484362_13 repeat protein - - - 0.000000002003 66.0
HKD1_k127_2484362_14 PFAM 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.0000004135 56.0
HKD1_k127_2484362_2 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 443.0
HKD1_k127_2484362_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 433.0
HKD1_k127_2484362_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001569 280.0
HKD1_k127_2484362_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002599 274.0
HKD1_k127_2484362_6 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005268 251.0
HKD1_k127_2484362_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000001675 188.0
HKD1_k127_2484362_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000003608 186.0
HKD1_k127_2484362_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000005677 129.0
HKD1_k127_2502467_0 Sulfatase K01130 - 3.1.6.1 0.0 1120.0
HKD1_k127_2502467_1 Protein of unknown function (DUF4230) - - - 0.000000000011 67.0
HKD1_k127_2568803_0 cytochrome C peroxidase - - - 8.306e-243 757.0
HKD1_k127_2568803_1 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 523.0
HKD1_k127_2568803_2 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 303.0
HKD1_k127_2568803_3 CHAT domain - - - 0.000000000000000000000000000000000000006491 155.0
HKD1_k127_259568_0 Cys/Met metabolism PLP-dependent enzyme K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 493.0
HKD1_k127_259568_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 492.0
HKD1_k127_259568_10 Belongs to the ompA family - - - 0.00000000000000000000000000000005195 134.0
HKD1_k127_259568_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000004177 139.0
HKD1_k127_259568_12 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000002328 128.0
HKD1_k127_259568_13 PFAM von Willebrand factor type A - - - 0.00000000000000000000000003273 121.0
HKD1_k127_259568_14 PFAM amino acid-binding ACT domain protein - - - 0.0000000000005776 74.0
HKD1_k127_259568_15 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000004793 67.0
HKD1_k127_259568_16 Disulphide bond corrector protein DsbC - - - 0.0000000001341 69.0
HKD1_k127_259568_2 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 370.0
HKD1_k127_259568_3 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 359.0
HKD1_k127_259568_4 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 295.0
HKD1_k127_259568_5 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001194 275.0
HKD1_k127_259568_6 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000000004124 226.0
HKD1_k127_259568_7 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000003805 210.0
HKD1_k127_259568_8 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000004358 206.0
HKD1_k127_259568_9 Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.0000000000000000000000000000000000000001168 160.0
HKD1_k127_2612326_0 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009603 537.0
HKD1_k127_2612326_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 496.0
HKD1_k127_2612326_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000002834 147.0
HKD1_k127_2612326_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000005773 145.0
HKD1_k127_2612326_12 Cytochrome c assembly protein - - - 0.0000000000000000000000000000001742 138.0
HKD1_k127_2612326_13 - - - - 0.000000000000000000000001549 117.0
HKD1_k127_2612326_14 Tfp pilus assembly protein FimV - - - 0.000000000000009309 85.0
HKD1_k127_2612326_15 von Willebrand factor, type A K07114 - - 0.00000001074 66.0
HKD1_k127_2612326_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 487.0
HKD1_k127_2612326_3 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K01749,K02303,K13542,K13543 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 441.0
HKD1_k127_2612326_4 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 428.0
HKD1_k127_2612326_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 363.0
HKD1_k127_2612326_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 341.0
HKD1_k127_2612326_7 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001213 290.0
HKD1_k127_2612326_8 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000025 231.0
HKD1_k127_2612326_9 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000001858 160.0
HKD1_k127_2630545_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1358.0
HKD1_k127_2630545_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1049.0
HKD1_k127_2630545_10 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 557.0
HKD1_k127_2630545_11 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 473.0
HKD1_k127_2630545_12 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 477.0
HKD1_k127_2630545_13 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 473.0
HKD1_k127_2630545_14 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 454.0
HKD1_k127_2630545_15 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 457.0
HKD1_k127_2630545_16 PFAM glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 428.0
HKD1_k127_2630545_17 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 406.0
HKD1_k127_2630545_18 Thiazole biosynthesis protein ThiG K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 365.0
HKD1_k127_2630545_19 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 368.0
HKD1_k127_2630545_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 9.372e-270 843.0
HKD1_k127_2630545_20 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 360.0
HKD1_k127_2630545_21 Osmosensitive K channel His kinase sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 338.0
HKD1_k127_2630545_22 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 346.0
HKD1_k127_2630545_23 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 338.0
HKD1_k127_2630545_24 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 325.0
HKD1_k127_2630545_25 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 313.0
HKD1_k127_2630545_26 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 311.0
HKD1_k127_2630545_27 Two component transcriptional regulator, winged helix family K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 298.0
HKD1_k127_2630545_28 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005075 288.0
HKD1_k127_2630545_29 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007706 273.0
HKD1_k127_2630545_3 Phosphate acyltransferases K01897 - 6.2.1.3 5.42e-233 750.0
HKD1_k127_2630545_30 Fad dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000122 273.0
HKD1_k127_2630545_31 Belongs to the PdxA family K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000003961 277.0
HKD1_k127_2630545_32 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009087 270.0
HKD1_k127_2630545_33 PFAM Bacterial low temperature requirement A protein (LtrA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003868 259.0
HKD1_k127_2630545_34 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002355 265.0
HKD1_k127_2630545_35 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000002699 250.0
HKD1_k127_2630545_36 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000003433 246.0
HKD1_k127_2630545_37 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000001043 253.0
HKD1_k127_2630545_38 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000009683 228.0
HKD1_k127_2630545_39 - - - - 0.00000000000000000000000000000000000000000000000000000000002839 217.0
HKD1_k127_2630545_4 Amino acid permease - - - 4.96e-230 728.0
HKD1_k127_2630545_40 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000004665 224.0
HKD1_k127_2630545_41 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.000000000000000000000000000000000000000000000000000000003897 226.0
HKD1_k127_2630545_42 RmlD substrate binding domain K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000006516 210.0
HKD1_k127_2630545_43 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000001655 205.0
HKD1_k127_2630545_44 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000101 197.0
HKD1_k127_2630545_45 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000001053 197.0
HKD1_k127_2630545_46 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000001088 190.0
HKD1_k127_2630545_47 DoxX - - - 0.00000000000000000000000000000000000000000000000007157 184.0
HKD1_k127_2630545_48 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000008664 172.0
HKD1_k127_2630545_49 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000003296 165.0
HKD1_k127_2630545_5 C-terminus of AA_permease K03294 - - 4.581e-206 649.0
HKD1_k127_2630545_50 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000000000000000009047 172.0
HKD1_k127_2630545_51 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000007284 154.0
HKD1_k127_2630545_52 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000003619 158.0
HKD1_k127_2630545_53 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000001477 151.0
HKD1_k127_2630545_54 Universal stress protein family - - - 0.00000000000000000000000000000000002991 147.0
HKD1_k127_2630545_55 DoxX-like family - - - 0.0000000000000000000000000000000003096 134.0
HKD1_k127_2630545_56 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000003577 139.0
HKD1_k127_2630545_57 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000007753 138.0
HKD1_k127_2630545_58 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000004108 134.0
HKD1_k127_2630545_6 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 1.246e-204 646.0
HKD1_k127_2630545_60 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000007676 121.0
HKD1_k127_2630545_61 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000002504 104.0
HKD1_k127_2630545_62 O-linked GlcNAc transferase - - - 0.000000000000000000000487 109.0
HKD1_k127_2630545_63 - - - - 0.000000000000000000002584 105.0
HKD1_k127_2630545_64 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000002029 92.0
HKD1_k127_2630545_65 Tetratricopeptide repeat - - - 0.00000000000000000007207 102.0
HKD1_k127_2630545_66 - - - - 0.0000000000000000025 94.0
HKD1_k127_2630545_67 Pfam:DUF2029 - - - 0.00000000000000001626 94.0
HKD1_k127_2630545_68 Belongs to the Nudix hydrolase family - - - 0.0000000000000007999 82.0
HKD1_k127_2630545_69 AntiSigma factor - - - 0.00000000000001471 83.0
HKD1_k127_2630545_7 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 604.0
HKD1_k127_2630545_70 6-phosphogluconolactonase activity - - - 0.000000000226 72.0
HKD1_k127_2630545_72 COG2335, Secreted and surface protein containing fasciclin-like repeats - - - 0.0000004718 61.0
HKD1_k127_2630545_73 - - - - 0.00001253 53.0
HKD1_k127_2630545_74 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00004989 52.0
HKD1_k127_2630545_8 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 610.0
HKD1_k127_2630545_9 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 566.0
HKD1_k127_268874_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1170.0
HKD1_k127_268874_1 Heat shock 70 kDa protein K04043 - - 4.98e-302 940.0
HKD1_k127_268874_10 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 329.0
HKD1_k127_268874_11 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 321.0
HKD1_k127_268874_12 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 294.0
HKD1_k127_268874_13 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 296.0
HKD1_k127_268874_14 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 291.0
HKD1_k127_268874_15 Udp N-acetylglucosamine O-acyltransferase; Domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001049 286.0
HKD1_k127_268874_16 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001561 263.0
HKD1_k127_268874_17 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000001992 239.0
HKD1_k127_268874_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000007311 242.0
HKD1_k127_268874_19 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000001094 196.0
HKD1_k127_268874_2 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 1.238e-265 840.0
HKD1_k127_268874_20 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000008778 183.0
HKD1_k127_268874_21 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000005382 160.0
HKD1_k127_268874_22 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000001407 160.0
HKD1_k127_268874_23 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.00000000000000000000000000000000001139 151.0
HKD1_k127_268874_25 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000009053 116.0
HKD1_k127_268874_26 WHG domain - - - 0.000000000000000000000001043 113.0
HKD1_k127_268874_27 FecR protein - - - 0.00000000000000000000002742 114.0
HKD1_k127_268874_28 - - - - 0.00000000000000000000007715 102.0
HKD1_k127_268874_29 fatty acid desaturase - - - 0.00000000000006718 83.0
HKD1_k127_268874_3 Transglycosylase K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 578.0
HKD1_k127_268874_30 PFAM S23 ribosomal protein - - - 0.000000000004314 79.0
HKD1_k127_268874_31 unfolded protein binding K06142 GO:0001530,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0019867,GO:0022417,GO:0022607,GO:0030288,GO:0030312,GO:0030313,GO:0031647,GO:0031975,GO:0032978,GO:0033036,GO:0034613,GO:0042597,GO:0042802,GO:0043163,GO:0043165,GO:0043170,GO:0044085,GO:0044091,GO:0044238,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0050821,GO:0051082,GO:0051179,GO:0051205,GO:0051234,GO:0051604,GO:0051641,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0070727,GO:0071704,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0097367,GO:1901564 - 0.0000001368 61.0
HKD1_k127_268874_32 Predicted membrane protein (DUF2085) - - - 0.00001109 55.0
HKD1_k127_268874_33 - - - - 0.00005155 48.0
HKD1_k127_268874_34 - - - - 0.0001721 50.0
HKD1_k127_268874_35 Outer membrane protein beta-barrel domain - - - 0.0002417 50.0
HKD1_k127_268874_4 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 545.0
HKD1_k127_268874_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 461.0
HKD1_k127_268874_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 432.0
HKD1_k127_268874_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 396.0
HKD1_k127_268874_8 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 379.0
HKD1_k127_268874_9 PFAM PfkB domain protein K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 342.0
HKD1_k127_2740623_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 1.472e-227 712.0
HKD1_k127_2740623_1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 8.167e-216 679.0
HKD1_k127_2740623_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 317.0
HKD1_k127_2740623_11 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 304.0
HKD1_k127_2740623_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 286.0
HKD1_k127_2740623_13 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000001706 243.0
HKD1_k127_2740623_14 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000003649 246.0
HKD1_k127_2740623_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000001549 216.0
HKD1_k127_2740623_16 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000001456 181.0
HKD1_k127_2740623_17 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000000000000000000003067 175.0
HKD1_k127_2740623_18 YCII-related domain - - - 0.00000000000000000000000000000005088 128.0
HKD1_k127_2740623_19 - - - - 0.0000000000000000000000000000003511 140.0
HKD1_k127_2740623_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 608.0
HKD1_k127_2740623_20 - - - - 0.000000000000000000000000000005215 124.0
HKD1_k127_2740623_21 oligosaccharyl transferase activity - - - 0.00000000000000000000000000001055 138.0
HKD1_k127_2740623_22 DUF167 K09131 - - 0.0000747 47.0
HKD1_k127_2740623_3 electron transfer activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 501.0
HKD1_k127_2740623_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250,K14268 - 2.6.1.19,2.6.1.22,2.6.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 497.0
HKD1_k127_2740623_5 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 487.0
HKD1_k127_2740623_6 tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 467.0
HKD1_k127_2740623_7 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 458.0
HKD1_k127_2740623_8 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 426.0
HKD1_k127_2740623_9 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 334.0
HKD1_k127_2743555_0 transmembrane transporter activity K03296,K07788,K07789 - - 0.0 1253.0
HKD1_k127_2743555_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.743e-285 897.0
HKD1_k127_2743555_10 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 376.0
HKD1_k127_2743555_11 Methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 366.0
HKD1_k127_2743555_12 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 369.0
HKD1_k127_2743555_13 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 334.0
HKD1_k127_2743555_14 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 326.0
HKD1_k127_2743555_15 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004933 274.0
HKD1_k127_2743555_16 Peptidase dimerisation domain K01439,K05831 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008891 284.0
HKD1_k127_2743555_17 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001442 275.0
HKD1_k127_2743555_18 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000005362 233.0
HKD1_k127_2743555_19 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000885 229.0
HKD1_k127_2743555_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 6.897e-259 807.0
HKD1_k127_2743555_20 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000007509 203.0
HKD1_k127_2743555_21 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000001719 198.0
HKD1_k127_2743555_22 - - - - 0.00000000000000000000000000000000000000002083 160.0
HKD1_k127_2743555_23 manganese ion transmembrane transporter activity - - - 0.00000000000000000000000000003693 136.0
HKD1_k127_2743555_24 DNA alkylation repair enzyme - - - 0.000000000000000000000001667 120.0
HKD1_k127_2743555_25 Alkylmercury lyase - - - 0.00000000000000001883 89.0
HKD1_k127_2743555_26 PFAM Formiminotransferase-cyclodeaminase - - - 0.0000000000000008402 85.0
HKD1_k127_2743555_27 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000004752 74.0
HKD1_k127_2743555_28 Alkylmercury lyase - - - 0.0000000002287 63.0
HKD1_k127_2743555_29 DivIVA protein K04074 - - 0.0000000005413 68.0
HKD1_k127_2743555_3 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 600.0
HKD1_k127_2743555_30 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000006591 53.0
HKD1_k127_2743555_31 Carboxypeptidase regulatory-like domain - - - 0.0001731 53.0
HKD1_k127_2743555_4 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 574.0
HKD1_k127_2743555_5 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 563.0
HKD1_k127_2743555_6 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 571.0
HKD1_k127_2743555_7 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 450.0
HKD1_k127_2743555_8 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 457.0
HKD1_k127_2743555_9 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 446.0
HKD1_k127_2756035_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.188e-319 992.0
HKD1_k127_2756035_1 efflux transmembrane transporter activity - - - 1.121e-226 728.0
HKD1_k127_2756035_10 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009992 378.0
HKD1_k127_2756035_11 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 389.0
HKD1_k127_2756035_12 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 367.0
HKD1_k127_2756035_13 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 344.0
HKD1_k127_2756035_14 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 368.0
HKD1_k127_2756035_15 type II secretion system protein E K02243,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 346.0
HKD1_k127_2756035_16 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 327.0
HKD1_k127_2756035_17 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 329.0
HKD1_k127_2756035_18 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 323.0
HKD1_k127_2756035_19 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 318.0
HKD1_k127_2756035_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.391e-223 702.0
HKD1_k127_2756035_20 haloacid dehalogenase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 291.0
HKD1_k127_2756035_21 extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009896 295.0
HKD1_k127_2756035_22 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003498 271.0
HKD1_k127_2756035_23 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004313 263.0
HKD1_k127_2756035_24 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009772 264.0
HKD1_k127_2756035_25 AAA domain K02450,K12283 - - 0.000000000000000000000000000000000000000000000000000000000000000003369 250.0
HKD1_k127_2756035_26 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.00000000000000000000000000000000000000000000000000000000000000005122 247.0
HKD1_k127_2756035_27 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000218 228.0
HKD1_k127_2756035_28 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000003128 239.0
HKD1_k127_2756035_29 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000313 225.0
HKD1_k127_2756035_3 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 8.204e-196 629.0
HKD1_k127_2756035_30 - - - - 0.0000000000000000000000000000000000000000000000000000004937 208.0
HKD1_k127_2756035_31 mitochondrion morphogenesis K06195 - - 0.0000000000000000000000000000000000000000000006783 176.0
HKD1_k127_2756035_32 Hydrolase of the alpha beta-hydrolase K07020 - - 0.0000000000000000000000000000000000000000000006867 174.0
HKD1_k127_2756035_33 Ferredoxin - - - 0.000000000000000000000000000000000000000000003603 167.0
HKD1_k127_2756035_34 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000005088 164.0
HKD1_k127_2756035_35 DinB family - - - 0.00000000000000000000000000000000001153 141.0
HKD1_k127_2756035_36 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000005827 136.0
HKD1_k127_2756035_37 PFAM phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000005545 139.0
HKD1_k127_2756035_38 BON domain - - - 0.00000000000000000000000000001437 125.0
HKD1_k127_2756035_39 - - - - 0.00000000000000000000000000202 118.0
HKD1_k127_2756035_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 586.0
HKD1_k127_2756035_40 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000001617 116.0
HKD1_k127_2756035_41 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000000002953 109.0
HKD1_k127_2756035_42 NMT1/THI5 like - - - 0.000000000000007186 86.0
HKD1_k127_2756035_43 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000002026 84.0
HKD1_k127_2756035_44 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000002125 82.0
HKD1_k127_2756035_45 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000001282 70.0
HKD1_k127_2756035_46 - - - - 0.000000001959 66.0
HKD1_k127_2756035_47 type IVB pilus formation outer membrane protein, R64 PilN family - - - 0.0000001184 64.0
HKD1_k127_2756035_48 Peptidase M56 - - - 0.000002763 59.0
HKD1_k127_2756035_49 snoRNA binding - - - 0.000003571 52.0
HKD1_k127_2756035_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 518.0
HKD1_k127_2756035_50 ubiE/COQ5 methyltransferase family - - - 0.00002216 53.0
HKD1_k127_2756035_51 Carboxypeptidase regulatory-like domain - - - 0.0002597 54.0
HKD1_k127_2756035_52 - - - - 0.0004237 48.0
HKD1_k127_2756035_6 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 494.0
HKD1_k127_2756035_7 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 502.0
HKD1_k127_2756035_8 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 481.0
HKD1_k127_2756035_9 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 457.0
HKD1_k127_2762248_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1138.0
HKD1_k127_2762248_1 Carboxypeptidase regulatory-like domain - - - 8.445e-267 859.0
HKD1_k127_2762248_10 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 426.0
HKD1_k127_2762248_11 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 417.0
HKD1_k127_2762248_12 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 407.0
HKD1_k127_2762248_13 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 404.0
HKD1_k127_2762248_14 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 386.0
HKD1_k127_2762248_15 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 374.0
HKD1_k127_2762248_16 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 374.0
HKD1_k127_2762248_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 342.0
HKD1_k127_2762248_18 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 322.0
HKD1_k127_2762248_19 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 321.0
HKD1_k127_2762248_2 Dehydrogenase K00117,K19813 - 1.1.5.2,1.1.5.9 1.767e-264 834.0
HKD1_k127_2762248_20 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 314.0
HKD1_k127_2762248_21 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 316.0
HKD1_k127_2762248_22 Phosphate transport system permease protein PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 287.0
HKD1_k127_2762248_23 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004174 288.0
HKD1_k127_2762248_24 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002949 265.0
HKD1_k127_2762248_25 PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000001016 246.0
HKD1_k127_2762248_26 glycerophosphodiester phosphodiesterase activity K01126 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000489 246.0
HKD1_k127_2762248_27 HAF family - - - 0.0000000000000000000000000000000000000000000000000000000000000006953 235.0
HKD1_k127_2762248_28 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.000000000000000000000000000000000000000000000000000000000000517 233.0
HKD1_k127_2762248_29 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000004917 212.0
HKD1_k127_2762248_3 Dehydrogenase K00117,K19813 - 1.1.5.2,1.1.5.9 1.182e-211 670.0
HKD1_k127_2762248_30 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000002135 189.0
HKD1_k127_2762248_31 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000003107 190.0
HKD1_k127_2762248_32 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000797 173.0
HKD1_k127_2762248_33 S4 RNA-binding domain K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000002719 170.0
HKD1_k127_2762248_34 PFAM Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000001288 156.0
HKD1_k127_2762248_35 - - - - 0.00000000000000000000000000000003774 133.0
HKD1_k127_2762248_36 PFAM Nickel cobalt transporter, high-affinity - - - 0.00000000000000000000000000002798 133.0
HKD1_k127_2762248_37 Nuclear protein SET K07117 - - 0.0000000000000000000007096 100.0
HKD1_k127_2762248_38 recA bacterial DNA recombination protein - - - 0.000000000000000000009362 101.0
HKD1_k127_2762248_39 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000001718 97.0
HKD1_k127_2762248_4 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 570.0
HKD1_k127_2762248_40 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.000000000000000002666 98.0
HKD1_k127_2762248_41 Transposase - - - 0.0000000000000003216 85.0
HKD1_k127_2762248_42 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000004415 85.0
HKD1_k127_2762248_43 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000169 76.0
HKD1_k127_2762248_45 Disulphide bond corrector protein DsbC - - - 0.0000002999 60.0
HKD1_k127_2762248_5 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 498.0
HKD1_k127_2762248_6 Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 454.0
HKD1_k127_2762248_7 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 443.0
HKD1_k127_2762248_8 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 447.0
HKD1_k127_2762248_9 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 428.0
HKD1_k127_2932619_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 4.586e-228 713.0
HKD1_k127_2932619_1 PFAM Peptidoglycan-binding domain 1 protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 393.0
HKD1_k127_2932619_2 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 344.0
HKD1_k127_2932619_3 Helix-hairpin-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001616 258.0
HKD1_k127_2932619_4 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000000000000000000007187 181.0
HKD1_k127_2932619_5 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000008919 159.0
HKD1_k127_2932619_6 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000001201 141.0
HKD1_k127_2932619_8 Glycosyl hydrolase family 57 K22278 - 3.5.1.104 0.00000000000000000000000000002778 126.0
HKD1_k127_2932619_9 Cbs domain K04767 - - 0.0000000000000000000006318 100.0
HKD1_k127_299435_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.518e-197 632.0
HKD1_k127_299435_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 439.0
HKD1_k127_3018714_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1377.0
HKD1_k127_3018714_1 Aminotransferase class-III K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008373 522.0
HKD1_k127_3018714_10 Bacillithiol biosynthesis BshC K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 327.0
HKD1_k127_3018714_11 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 319.0
HKD1_k127_3018714_12 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 295.0
HKD1_k127_3018714_13 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000001914 266.0
HKD1_k127_3018714_14 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006122 275.0
HKD1_k127_3018714_15 PFAM MazG nucleotide pyrophosphohydrolase K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000127 254.0
HKD1_k127_3018714_16 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000001917 252.0
HKD1_k127_3018714_17 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000004918 238.0
HKD1_k127_3018714_18 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000003523 232.0
HKD1_k127_3018714_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 506.0
HKD1_k127_3018714_20 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000184 147.0
HKD1_k127_3018714_21 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000005483 139.0
HKD1_k127_3018714_22 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000006723 125.0
HKD1_k127_3018714_23 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000006836 123.0
HKD1_k127_3018714_24 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000006021 111.0
HKD1_k127_3018714_25 - - - - 0.0000000000000000000000003128 121.0
HKD1_k127_3018714_26 serine threonine protein kinase K08884 - 2.7.11.1 0.000000000000000000008056 108.0
HKD1_k127_3018714_27 Domain of unknown function (DUF1844) - - - 0.00000000000000001039 87.0
HKD1_k127_3018714_28 Modulates RecA activity K03565 - - 0.00000006424 62.0
HKD1_k127_3018714_29 - - - - 0.000002578 49.0
HKD1_k127_3018714_3 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 516.0
HKD1_k127_3018714_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 452.0
HKD1_k127_3018714_5 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 440.0
HKD1_k127_3018714_6 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 433.0
HKD1_k127_3018714_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 431.0
HKD1_k127_3018714_8 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 413.0
HKD1_k127_3018714_9 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 412.0
HKD1_k127_3036278_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K02182 GO:0003674,GO:0003824,GO:0016405,GO:0016874,GO:0016877,GO:0016879,GO:0016881,GO:0051108,GO:0051109 6.2.1.48 3.584e-227 714.0
HKD1_k127_3036278_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 456.0
HKD1_k127_3036278_2 Enoyl-CoA hydratase/isomerase K01661,K07536 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 398.0
HKD1_k127_3036278_3 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 293.0
HKD1_k127_3049718_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 610.0
HKD1_k127_3049718_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 567.0
HKD1_k127_3049718_2 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 553.0
HKD1_k127_3049718_3 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 524.0
HKD1_k127_3049718_4 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000001483 199.0
HKD1_k127_3049718_5 Trypsin-like peptidase domain K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.00000004222 60.0
HKD1_k127_3052564_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 441.0
HKD1_k127_3052564_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 314.0
HKD1_k127_3052564_2 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 311.0
HKD1_k127_3052564_3 Sigma-70, region 4 K02405 - - 0.000000000000000000000000000000000000003641 158.0
HKD1_k127_3052564_4 DUF218 domain - - - 0.000000000000000000693 96.0
HKD1_k127_3052564_5 Stress responsive A/B Barrel Domain - - - 0.000007103 54.0
HKD1_k127_3070436_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 623.0
HKD1_k127_3070436_1 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 588.0
HKD1_k127_3070436_10 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002729 274.0
HKD1_k127_3070436_11 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003408 265.0
HKD1_k127_3070436_12 region 4 type 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003888 254.0
HKD1_k127_3070436_13 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000001386 242.0
HKD1_k127_3070436_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001052 228.0
HKD1_k127_3070436_15 - - - - 0.00000000000000000000000000000000000000000000000000000000006419 212.0
HKD1_k127_3070436_16 Cupin 2, conserved barrel domain protein K06720 - 4.2.1.108 0.000000000000000000000000000000000000000000000000000000001621 207.0
HKD1_k127_3070436_17 Methyltransferase domain - GO:0002682,GO:0002683,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0031347,GO:0031348,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046467,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000006576 206.0
HKD1_k127_3070436_18 proline dipeptidase activity K08688 - 3.5.3.3 0.00000000000000000000000000000000000000000000001185 190.0
HKD1_k127_3070436_19 MmgE/PrpD family - - - 0.00000000000000000000000000000000000001439 162.0
HKD1_k127_3070436_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 426.0
HKD1_k127_3070436_20 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000001506 135.0
HKD1_k127_3070436_21 - - - - 0.00000000000000000000000000000009081 128.0
HKD1_k127_3070436_22 - - - - 0.000000000000000000000000000001029 138.0
HKD1_k127_3070436_23 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000001323 118.0
HKD1_k127_3070436_24 ligase activity K01474 - 3.5.2.14 0.000000000000000000004282 108.0
HKD1_k127_3070436_25 PFAM Nitroreductase - - - 0.000000000000004171 87.0
HKD1_k127_3070436_26 Creatinase/Prolidase N-terminal domain K01271,K15783 - 3.4.13.9,3.5.4.44 0.00000000000008892 83.0
HKD1_k127_3070436_28 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000002701 77.0
HKD1_k127_3070436_29 protease-associated PA domain protein - - - 0.00000007341 65.0
HKD1_k127_3070436_3 Glycosyl transferase, family 2 K10012,K12999,K13670 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009818 366.0
HKD1_k127_3070436_4 self proteolysis K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 369.0
HKD1_k127_3070436_5 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 359.0
HKD1_k127_3070436_6 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 315.0
HKD1_k127_3070436_7 beta-fructofuranosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 299.0
HKD1_k127_3070436_8 WbqC-like protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 287.0
HKD1_k127_3070436_9 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003263 280.0
HKD1_k127_3105414_0 Protein of unknown function (DUF1254) - - - 3.579e-219 696.0
HKD1_k127_3105414_1 Nitrate nitrite response regulator protein K07685 - - 0.0000000145 61.0
HKD1_k127_3106398_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 5.354e-221 717.0
HKD1_k127_3106398_1 PFAM ribonuclease II K01147 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 565.0
HKD1_k127_3106398_2 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 499.0
HKD1_k127_3106398_3 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 429.0
HKD1_k127_3106398_4 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 389.0
HKD1_k127_3106398_5 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000267 285.0
HKD1_k127_3106398_6 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000006179 180.0
HKD1_k127_3106398_7 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000008621 179.0
HKD1_k127_3106398_8 Thiol-disulfide oxidoreductase DCC - - - 0.00000000000000000000000000002048 122.0
HKD1_k127_3106747_0 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 379.0
HKD1_k127_3106747_1 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 394.0
HKD1_k127_3106747_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 338.0
HKD1_k127_3106747_3 Gaf domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009876 286.0
HKD1_k127_3106747_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003712 276.0
HKD1_k127_3106747_5 Glycine zipper - - - 0.0000000000000000000000000000000000000000000005453 173.0
HKD1_k127_3106747_6 Predicted membrane protein (DUF2127) - - - 0.00000000000000000000000000000187 130.0
HKD1_k127_3106747_7 CsbD-like - - - 0.00000000000004069 74.0
HKD1_k127_3106747_8 alpha beta - - - 0.0001328 53.0
HKD1_k127_3106747_9 Domain of unknown function (DUF4382) - - - 0.0005298 45.0
HKD1_k127_3143534_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 2.635e-269 843.0
HKD1_k127_3143534_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 523.0
HKD1_k127_3172364_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000002303 126.0
HKD1_k127_3175701_0 Methionine synthase K00548 - 2.1.1.13 0.0 1614.0
HKD1_k127_3175701_1 Peptidase M14, carboxypeptidase A - - - 0.0 1068.0
HKD1_k127_3175701_10 Dienelactone hydrolase family - - - 4.149e-225 718.0
HKD1_k127_3175701_100 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000002835 100.0
HKD1_k127_3175701_102 23S rRNA-intervening sequence protein - - - 0.000000000000000004497 89.0
HKD1_k127_3175701_103 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03817 - - 0.00000000000001823 85.0
HKD1_k127_3175701_104 - - - - 0.00000000000006107 85.0
HKD1_k127_3175701_105 SNARE associated Golgi protein - - - 0.0000000000002637 77.0
HKD1_k127_3175701_106 Methyltransferase domain - - - 0.00000000001161 77.0
HKD1_k127_3175701_107 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000006385 63.0
HKD1_k127_3175701_108 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000003693 64.0
HKD1_k127_3175701_109 oxidoreductase activity - - - 0.000000003832 70.0
HKD1_k127_3175701_11 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.238e-214 676.0
HKD1_k127_3175701_110 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000003125 57.0
HKD1_k127_3175701_111 Aerotolerance regulator N-terminal - - - 0.000004096 59.0
HKD1_k127_3175701_112 conserved protein, contains double-stranded beta-helix domain - - - 0.00007617 54.0
HKD1_k127_3175701_113 toxin-antitoxin pair type II binding - - - 0.0001104 48.0
HKD1_k127_3175701_12 Carbohydrate family 9 binding domain-like - - - 2.042e-200 652.0
HKD1_k127_3175701_13 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 635.0
HKD1_k127_3175701_14 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 631.0
HKD1_k127_3175701_15 imidazolonepropionase activity K00466 - 1.13.12.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 582.0
HKD1_k127_3175701_16 transmembrane transporter activity K08196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009512 573.0
HKD1_k127_3175701_17 PFAM Gamma-glutamyltranspeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 571.0
HKD1_k127_3175701_18 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 579.0
HKD1_k127_3175701_19 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 550.0
HKD1_k127_3175701_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.272e-314 981.0
HKD1_k127_3175701_20 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 538.0
HKD1_k127_3175701_21 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 524.0
HKD1_k127_3175701_22 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 499.0
HKD1_k127_3175701_23 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 467.0
HKD1_k127_3175701_24 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 483.0
HKD1_k127_3175701_25 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 452.0
HKD1_k127_3175701_26 Associated with various cellular activities K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 460.0
HKD1_k127_3175701_27 ABC-type multidrug transport system ATPase and permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 458.0
HKD1_k127_3175701_28 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 428.0
HKD1_k127_3175701_29 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 416.0
HKD1_k127_3175701_3 Glutamine synthetase type III K01915 - 6.3.1.2 9.765e-308 959.0
HKD1_k127_3175701_30 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 407.0
HKD1_k127_3175701_31 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 409.0
HKD1_k127_3175701_32 Transketolase, pyrimidine binding domain K00162,K00167,K21417 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944,GO:0140030,GO:0140032 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 384.0
HKD1_k127_3175701_33 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 374.0
HKD1_k127_3175701_34 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 375.0
HKD1_k127_3175701_35 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 385.0
HKD1_k127_3175701_36 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 344.0
HKD1_k127_3175701_37 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 344.0
HKD1_k127_3175701_38 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 360.0
HKD1_k127_3175701_39 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 342.0
HKD1_k127_3175701_4 topoisomerase K02469 - 5.99.1.3 4.238e-284 894.0
HKD1_k127_3175701_40 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 332.0
HKD1_k127_3175701_41 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 335.0
HKD1_k127_3175701_42 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 324.0
HKD1_k127_3175701_43 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 321.0
HKD1_k127_3175701_44 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 337.0
HKD1_k127_3175701_45 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 316.0
HKD1_k127_3175701_46 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 312.0
HKD1_k127_3175701_47 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 314.0
HKD1_k127_3175701_48 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 307.0
HKD1_k127_3175701_49 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 310.0
HKD1_k127_3175701_5 PFAM LmbE family protein K22136 - - 9.679e-274 869.0
HKD1_k127_3175701_50 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 296.0
HKD1_k127_3175701_51 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 295.0
HKD1_k127_3175701_52 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 297.0
HKD1_k127_3175701_53 Ketopantoate reductase PanE/ApbA C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 293.0
HKD1_k127_3175701_54 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001323 278.0
HKD1_k127_3175701_55 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001538 291.0
HKD1_k127_3175701_56 Acetamidase formamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009332 286.0
HKD1_k127_3175701_57 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004075 287.0
HKD1_k127_3175701_58 PFAM dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005656 269.0
HKD1_k127_3175701_59 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006558 286.0
HKD1_k127_3175701_6 COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit K02470,K02622 - 5.99.1.3 1.903e-270 873.0
HKD1_k127_3175701_60 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004189 269.0
HKD1_k127_3175701_61 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001531 260.0
HKD1_k127_3175701_62 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005196 280.0
HKD1_k127_3175701_63 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002163 262.0
HKD1_k127_3175701_64 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000364 277.0
HKD1_k127_3175701_65 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001236 263.0
HKD1_k127_3175701_66 ATPase involved in DNA repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000001295 254.0
HKD1_k127_3175701_67 PFAM Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000003844 236.0
HKD1_k127_3175701_68 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000001124 239.0
HKD1_k127_3175701_69 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000003926 237.0
HKD1_k127_3175701_7 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 2.397e-266 832.0
HKD1_k127_3175701_70 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000002039 246.0
HKD1_k127_3175701_71 - K06921 - - 0.000000000000000000000000000000000000000000000000000000000000001923 232.0
HKD1_k127_3175701_72 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000009997 223.0
HKD1_k127_3175701_73 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000001379 230.0
HKD1_k127_3175701_74 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000001676 230.0
HKD1_k127_3175701_75 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000005637 202.0
HKD1_k127_3175701_76 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000001763 204.0
HKD1_k127_3175701_77 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000003172 189.0
HKD1_k127_3175701_78 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000002821 179.0
HKD1_k127_3175701_79 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000004314 175.0
HKD1_k127_3175701_8 AMP-binding enzyme C-terminal domain K00666 - - 1.097e-240 752.0
HKD1_k127_3175701_80 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000002098 186.0
HKD1_k127_3175701_81 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000001528 179.0
HKD1_k127_3175701_82 NUDIX domain - - - 0.0000000000000000000000000000000000000000275 159.0
HKD1_k127_3175701_83 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000103 156.0
HKD1_k127_3175701_84 Amino acid oxidase - - - 0.0000000000000000000000000000000000000001811 165.0
HKD1_k127_3175701_86 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000006632 141.0
HKD1_k127_3175701_87 GDSL-like lipase acylhydrolase domain protein - - - 0.000000000000000000000000000000000003831 151.0
HKD1_k127_3175701_88 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000129 141.0
HKD1_k127_3175701_89 methyltransferase activity - - - 0.00000000000000000000000000000000003031 142.0
HKD1_k127_3175701_9 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 2.849e-233 731.0
HKD1_k127_3175701_90 GlcNAc-PI de-N-acetylase K15525 - 3.5.1.103 0.000000000000000000000000000000001015 140.0
HKD1_k127_3175701_91 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000006667 124.0
HKD1_k127_3175701_93 von Willebrand factor, type A - - - 0.00000000000000000000000000001744 137.0
HKD1_k127_3175701_94 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000586 120.0
HKD1_k127_3175701_96 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000039 113.0
HKD1_k127_3175701_97 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000009511 115.0
HKD1_k127_3175701_98 DinB superfamily - - - 0.000000000000000000000001497 110.0
HKD1_k127_3175701_99 PFAM Bacterial regulatory proteins, gntR family K07979 - - 0.000000000000000000000074 102.0
HKD1_k127_3183955_0 Beta-lactamase class C - - - 2.303e-205 653.0
HKD1_k127_3183955_10 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009555 259.0
HKD1_k127_3183955_12 YqcI/YcgG family - - - 0.000000000000000000000000000000000000000000000000000000009677 204.0
HKD1_k127_3183955_13 Phosphatidylethanolamine-binding protein - - - 0.0000000000000000000000000000000000000000000001676 175.0
HKD1_k127_3183955_15 Protein of unknown function (DUF3179) - - - 0.0000000000000000000000000000000006206 139.0
HKD1_k127_3183955_16 - - - - 0.000000000000000000000000000244 125.0
HKD1_k127_3183955_17 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000002932 107.0
HKD1_k127_3183955_18 Cupin domain - - - 0.00000000000000000001271 97.0
HKD1_k127_3183955_19 Protein of unknown function (DUF3179) - - - 0.00000008366 57.0
HKD1_k127_3183955_2 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 454.0
HKD1_k127_3183955_3 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 434.0
HKD1_k127_3183955_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 415.0
HKD1_k127_3183955_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 352.0
HKD1_k127_3183955_6 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 347.0
HKD1_k127_3183955_7 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 318.0
HKD1_k127_3183955_8 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000194 289.0
HKD1_k127_3183955_9 RimK-like ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005159 283.0
HKD1_k127_3497548_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 380.0
HKD1_k127_3497548_1 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 371.0
HKD1_k127_3497548_10 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000002843 201.0
HKD1_k127_3497548_11 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000000003364 214.0
HKD1_k127_3497548_12 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000005332 211.0
HKD1_k127_3497548_13 - - - - 0.00000000000000000000000000000000000000000000000000008321 208.0
HKD1_k127_3497548_14 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000004304 202.0
HKD1_k127_3497548_15 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000218 189.0
HKD1_k127_3497548_16 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000001191 191.0
HKD1_k127_3497548_17 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000817 156.0
HKD1_k127_3497548_18 polysaccharide deacetylase - - - 0.000000000000000000000000000000000001638 153.0
HKD1_k127_3497548_19 Glycosyl transferase 4-like domain K03525 - 2.7.1.33 0.0000000000000000000000000000000001369 148.0
HKD1_k127_3497548_2 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 353.0
HKD1_k127_3497548_20 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000003445 135.0
HKD1_k127_3497548_21 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000003791 123.0
HKD1_k127_3497548_22 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.0000000000000000000000000002018 121.0
HKD1_k127_3497548_23 oligosaccharyl transferase activity K00721 - 2.4.1.83 0.00000000000000000000000000214 127.0
HKD1_k127_3497548_24 Methyltransferase domain - - - 0.000000000000000000001951 107.0
HKD1_k127_3497548_25 Methyltransferase domain - - - 0.0000000000000000001055 100.0
HKD1_k127_3497548_26 PFAM SNARE associated Golgi protein - - - 0.0000000000000000008343 94.0
HKD1_k127_3497548_27 Polysaccharide biosynthesis protein - - - 0.000000000000000009818 98.0
HKD1_k127_3497548_28 domain protein - - - 0.000000000000003168 88.0
HKD1_k127_3497548_3 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 342.0
HKD1_k127_3497548_31 GDSL-like Lipase/Acylhydrolase - - - 0.000000004918 69.0
HKD1_k127_3497548_32 GDSL-like Lipase/Acylhydrolase family - - - 0.0000004301 62.0
HKD1_k127_3497548_33 - - - - 0.000005464 55.0
HKD1_k127_3497548_34 Fibronectin type 3 domain - - - 0.000007443 59.0
HKD1_k127_3497548_35 6-phosphogluconolactonase activity - - - 0.00002944 56.0
HKD1_k127_3497548_4 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000009984 249.0
HKD1_k127_3497548_5 O-acyltransferase activity K00661 - 2.3.1.79 0.0000000000000000000000000000000000000000000000000000000000000000001691 238.0
HKD1_k127_3497548_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001212 229.0
HKD1_k127_3497548_7 Xanthine dehydrogenase K13479,K16878 GO:0000166,GO:0003674,GO:0003824,GO:0004854,GO:0005488,GO:0006139,GO:0006144,GO:0006145,GO:0006150,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009114,GO:0009987,GO:0016491,GO:0016725,GO:0016726,GO:0019439,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046100,GO:0046113,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071949,GO:0072521,GO:0072523,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575 1.17.1.4,1.3.99.8 0.000000000000000000000000000000000000000000000000000000000000001971 228.0
HKD1_k127_3497548_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000131 212.0
HKD1_k127_3497548_9 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000003617 214.0
HKD1_k127_3565707_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1022.0
HKD1_k127_3565707_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.703e-235 741.0
HKD1_k127_3565707_10 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 442.0
HKD1_k127_3565707_11 Mur ligase middle domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 440.0
HKD1_k127_3565707_12 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 424.0
HKD1_k127_3565707_13 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 406.0
HKD1_k127_3565707_14 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 406.0
HKD1_k127_3565707_15 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 392.0
HKD1_k127_3565707_16 4Fe-4S ferredoxin iron-sulfur binding domain protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 358.0
HKD1_k127_3565707_17 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 373.0
HKD1_k127_3565707_18 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 355.0
HKD1_k127_3565707_19 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 368.0
HKD1_k127_3565707_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 3.803e-222 694.0
HKD1_k127_3565707_20 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 340.0
HKD1_k127_3565707_21 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 340.0
HKD1_k127_3565707_22 pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 338.0
HKD1_k127_3565707_23 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009155 333.0
HKD1_k127_3565707_24 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 330.0
HKD1_k127_3565707_25 Type ii and iii secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 331.0
HKD1_k127_3565707_26 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 322.0
HKD1_k127_3565707_27 Helix-hairpin-helix domain K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 323.0
HKD1_k127_3565707_28 transferase activity, transferring acyl groups other than amino-acyl groups K13663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 312.0
HKD1_k127_3565707_29 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 299.0
HKD1_k127_3565707_3 amino acid K03294 - - 4.236e-206 651.0
HKD1_k127_3565707_30 TIGRFAM urea amidolyase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 296.0
HKD1_k127_3565707_31 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001354 289.0
HKD1_k127_3565707_32 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007038 276.0
HKD1_k127_3565707_33 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000399 282.0
HKD1_k127_3565707_34 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005868 271.0
HKD1_k127_3565707_35 RibD C-terminal domain K00082,K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000002783 270.0
HKD1_k127_3565707_36 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001222 266.0
HKD1_k127_3565707_37 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000002121 245.0
HKD1_k127_3565707_38 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000001391 238.0
HKD1_k127_3565707_39 Allophanate hydrolase subunit 1 K06351 - - 0.00000000000000000000000000000000000000000000000000000000000001098 229.0
HKD1_k127_3565707_4 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 599.0
HKD1_k127_3565707_40 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.000000000000000000000000000000000000000000000000000000006292 209.0
HKD1_k127_3565707_41 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000006569 214.0
HKD1_k127_3565707_42 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000002424 201.0
HKD1_k127_3565707_43 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000004257 191.0
HKD1_k127_3565707_44 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000866 196.0
HKD1_k127_3565707_45 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000002432 184.0
HKD1_k127_3565707_46 Diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000002816 186.0
HKD1_k127_3565707_47 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000002821 179.0
HKD1_k127_3565707_48 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000004581 194.0
HKD1_k127_3565707_49 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000008497 168.0
HKD1_k127_3565707_5 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 587.0
HKD1_k127_3565707_50 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000003215 173.0
HKD1_k127_3565707_51 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000002449 169.0
HKD1_k127_3565707_52 Platelet-activating factor acetylhydrolase, isoform II - - - 0.00000000000000000000000000000000000000000002467 177.0
HKD1_k127_3565707_53 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000002037 164.0
HKD1_k127_3565707_54 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000001208 148.0
HKD1_k127_3565707_55 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000002158 138.0
HKD1_k127_3565707_56 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000005331 140.0
HKD1_k127_3565707_57 YXWGXW repeat (2 copies) - - - 0.00000000000000000000000000000001262 135.0
HKD1_k127_3565707_58 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000001524 131.0
HKD1_k127_3565707_59 - - - - 0.000000000000000000000000001471 122.0
HKD1_k127_3565707_6 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 560.0
HKD1_k127_3565707_60 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000000000000006252 117.0
HKD1_k127_3565707_61 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000001359 108.0
HKD1_k127_3565707_62 transcriptional regulator PadR family - - - 0.0000000000000000000000385 102.0
HKD1_k127_3565707_63 - K00241 - - 0.0000000000000000000006886 101.0
HKD1_k127_3565707_64 outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000009046 103.0
HKD1_k127_3565707_65 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000004672 98.0
HKD1_k127_3565707_66 Cytochrome c - - - 0.0000000000000000006188 91.0
HKD1_k127_3565707_67 Tetratricopeptide repeat - - - 0.00000000000000000606 98.0
HKD1_k127_3565707_69 Helix-turn-helix domain K15539 - - 0.00000000000000004427 93.0
HKD1_k127_3565707_7 DNA polymerase X K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 527.0
HKD1_k127_3565707_70 O-methyltransferase - - - 0.000000000000002413 86.0
HKD1_k127_3565707_72 Belongs to the UPF0109 family K06960 - - 0.000000000000006703 78.0
HKD1_k127_3565707_73 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000002181 82.0
HKD1_k127_3565707_74 Tetratricopeptide repeats - - - 0.0000000000008742 76.0
HKD1_k127_3565707_75 - - - - 0.00000000004978 68.0
HKD1_k127_3565707_76 transcriptional regulator, ArsR family - - - 0.000000009261 61.0
HKD1_k127_3565707_77 - - - - 0.000001381 54.0
HKD1_k127_3565707_78 Pilus assembly protein, PilP K02665 - - 0.000009327 55.0
HKD1_k127_3565707_79 Fimbrial assembly protein (PilN) - - - 0.00003093 54.0
HKD1_k127_3565707_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 496.0
HKD1_k127_3565707_9 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 479.0
HKD1_k127_3566289_0 PFAM Peptidase M11 gametolysin - - - 0.00000000000000000000000000000000000000000001676 184.0
HKD1_k127_3566289_1 beta-fructofuranosidase activity - - - 0.000000000000000000000000000537 132.0
HKD1_k127_3566289_3 Unextendable partial coding region - - - 0.0008684 44.0
HKD1_k127_3571426_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1022.0
HKD1_k127_3571426_1 Pyrrolo-quinoline quinone K00114 - 1.1.2.8 1.623e-228 722.0
HKD1_k127_3571426_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 499.0
HKD1_k127_3571426_3 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 409.0
HKD1_k127_3571426_4 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 383.0
HKD1_k127_3571426_5 Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 333.0
HKD1_k127_3571426_6 Belongs to the HpcH HpaI aldolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007084 286.0
HKD1_k127_3571426_7 Fungal trichothecene efflux pump (TRI12) - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000111 261.0
HKD1_k127_3571426_8 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000492 156.0
HKD1_k127_3642934_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.156e-289 908.0
HKD1_k127_3642934_1 PFAM Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 582.0
HKD1_k127_3642934_10 Quinohemoprotein amine dehydrogenase, gamma subunit - - - 0.0000000000000000000000000000000000000001014 159.0
HKD1_k127_3642934_11 EVE domain - - - 0.0000000000000000000000000000000000007483 144.0
HKD1_k127_3642934_12 - - - - 0.0000000001306 73.0
HKD1_k127_3642934_13 23S rRNA-intervening sequence protein - - - 0.000000004928 67.0
HKD1_k127_3642934_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 502.0
HKD1_k127_3642934_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 467.0
HKD1_k127_3642934_4 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 388.0
HKD1_k127_3642934_5 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002985 291.0
HKD1_k127_3642934_6 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000004669 237.0
HKD1_k127_3642934_7 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000001075 226.0
HKD1_k127_3642934_8 G/U mismatch-specific uracil-DNA glycosylase activity K01934,K03649 GO:0000700,GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008263,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.28,6.3.3.2 0.000000000000000000000000000000000000000000000004758 177.0
HKD1_k127_3642934_9 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000003746 192.0
HKD1_k127_3797242_0 efflux transmembrane transporter activity - - - 3.043e-209 669.0
HKD1_k127_3797242_1 PQQ enzyme repeat K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001091 255.0
HKD1_k127_3815679_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1164.0
HKD1_k127_3815679_1 Heat shock 70 kDa protein K04043 - - 1.756e-289 901.0
HKD1_k127_3815679_10 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 558.0
HKD1_k127_3815679_11 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 462.0
HKD1_k127_3815679_12 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 469.0
HKD1_k127_3815679_13 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 469.0
HKD1_k127_3815679_14 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 445.0
HKD1_k127_3815679_15 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 438.0
HKD1_k127_3815679_16 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 379.0
HKD1_k127_3815679_17 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 372.0
HKD1_k127_3815679_18 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 357.0
HKD1_k127_3815679_19 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008229 344.0
HKD1_k127_3815679_2 GTP-binding protein TypA K06207 - - 2.626e-265 828.0
HKD1_k127_3815679_20 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 330.0
HKD1_k127_3815679_21 ATPases associated with a variety of cellular activities K05847 GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 312.0
HKD1_k127_3815679_22 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 304.0
HKD1_k127_3815679_23 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005147 286.0
HKD1_k127_3815679_24 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000559 293.0
HKD1_k127_3815679_25 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003133 286.0
HKD1_k127_3815679_26 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004391 299.0
HKD1_k127_3815679_27 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000911 263.0
HKD1_k127_3815679_28 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004875 259.0
HKD1_k127_3815679_29 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000001289 255.0
HKD1_k127_3815679_3 protein secretion by the type I secretion system K11085 - - 5.351e-244 791.0
HKD1_k127_3815679_30 Ribosomal RNA large subunit methyltransferase J K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000211 248.0
HKD1_k127_3815679_31 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000006934 240.0
HKD1_k127_3815679_32 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000001725 236.0
HKD1_k127_3815679_33 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000003164 223.0
HKD1_k127_3815679_34 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000004992 237.0
HKD1_k127_3815679_35 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000002472 219.0
HKD1_k127_3815679_36 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000722 194.0
HKD1_k127_3815679_37 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000004617 184.0
HKD1_k127_3815679_38 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000004764 169.0
HKD1_k127_3815679_39 AMMECR1 K09141 - - 0.000000000000000000000000000000000000009434 156.0
HKD1_k127_3815679_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 3.035e-236 767.0
HKD1_k127_3815679_40 Protein of unknown function (DUF2089) - - - 0.0000000000000000000000000000000000002909 145.0
HKD1_k127_3815679_41 integral membrane protein - - - 0.000000000000000000000000000000000000816 154.0
HKD1_k127_3815679_42 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000008842 143.0
HKD1_k127_3815679_43 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000001202 141.0
HKD1_k127_3815679_44 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000001014 132.0
HKD1_k127_3815679_45 MgtC family K07507 - - 0.0000000000000000000000000000008207 126.0
HKD1_k127_3815679_46 S1/P1 Nuclease - - - 0.00000000000000000000000000006411 127.0
HKD1_k127_3815679_47 membrane-bound metal-dependent hydrolase K07038 - - 0.00000000000000000000000000007578 130.0
HKD1_k127_3815679_48 peptidase - - - 0.00000000000000000000001438 116.0
HKD1_k127_3815679_49 - - - - 0.000000000000000000257 93.0
HKD1_k127_3815679_5 Peptidase family M49 - - - 6.979e-219 692.0
HKD1_k127_3815679_50 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000005362 87.0
HKD1_k127_3815679_51 Regulatory protein, FmdB family - - - 0.000000000000001396 85.0
HKD1_k127_3815679_52 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000002283 78.0
HKD1_k127_3815679_53 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000001013 79.0
HKD1_k127_3815679_54 - - - - 0.0000000000002207 79.0
HKD1_k127_3815679_55 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000008661 71.0
HKD1_k127_3815679_56 Matrixin - - - 0.000000000004158 77.0
HKD1_k127_3815679_57 Hsp20/alpha crystallin family K13993 - - 0.0000000005178 66.0
HKD1_k127_3815679_58 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000001691 53.0
HKD1_k127_3815679_6 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.502e-206 662.0
HKD1_k127_3815679_7 Ammonium Transporter K03320 - - 3.979e-199 630.0
HKD1_k127_3815679_8 efflux transmembrane transporter activity - - - 3.113e-197 640.0
HKD1_k127_3815679_9 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 588.0
HKD1_k127_385401_0 C-terminus of AA_permease K03294 - - 1.372e-207 673.0
HKD1_k127_385401_1 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 340.0
HKD1_k127_385401_10 NlpC P60 family protein - - - 0.000000000000000000000000000000002842 137.0
HKD1_k127_385401_11 - - - - 0.000000000004338 76.0
HKD1_k127_385401_2 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 347.0
HKD1_k127_385401_3 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003961 267.0
HKD1_k127_385401_4 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004004 244.0
HKD1_k127_385401_5 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000008545 257.0
HKD1_k127_385401_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000007226 214.0
HKD1_k127_385401_7 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000001122 205.0
HKD1_k127_385401_8 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000006172 201.0
HKD1_k127_385401_9 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000001487 196.0
HKD1_k127_3913001_0 Fumarase C C-terminus K01744 - 4.3.1.1 1.745e-209 664.0
HKD1_k127_3913001_1 Predicted Permease Membrane Region K07085 - - 7.915e-203 645.0
HKD1_k127_3913001_10 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003217 262.0
HKD1_k127_3913001_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000006885 244.0
HKD1_k127_3913001_12 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000435 183.0
HKD1_k127_3913001_13 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000449 46.0
HKD1_k127_3913001_2 SMART Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 593.0
HKD1_k127_3913001_3 Inorganic ion transport and metabolism K03319 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 459.0
HKD1_k127_3913001_4 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 457.0
HKD1_k127_3913001_5 Belongs to the asparaginase 1 family K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 396.0
HKD1_k127_3913001_6 Involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 381.0
HKD1_k127_3913001_7 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 324.0
HKD1_k127_3913001_8 tryptophan 2,3-dioxygenase activity K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 324.0
HKD1_k127_3913001_9 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001133 269.0
HKD1_k127_3930303_0 DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.0 1146.0
HKD1_k127_3930303_1 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 4.45e-265 844.0
HKD1_k127_3930303_10 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 438.0
HKD1_k127_3930303_11 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 411.0
HKD1_k127_3930303_12 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 390.0
HKD1_k127_3930303_13 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 376.0
HKD1_k127_3930303_14 symporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 383.0
HKD1_k127_3930303_15 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 342.0
HKD1_k127_3930303_16 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 327.0
HKD1_k127_3930303_17 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 336.0
HKD1_k127_3930303_18 PFAM WD40 domain protein beta Propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 352.0
HKD1_k127_3930303_19 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 319.0
HKD1_k127_3930303_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 7.714e-203 643.0
HKD1_k127_3930303_20 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 302.0
HKD1_k127_3930303_21 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 301.0
HKD1_k127_3930303_22 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 294.0
HKD1_k127_3930303_23 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 293.0
HKD1_k127_3930303_24 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001841 289.0
HKD1_k127_3930303_25 Glucosamine-6-phosphate deaminase K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001933 273.0
HKD1_k127_3930303_26 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000009678 244.0
HKD1_k127_3930303_27 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000002131 217.0
HKD1_k127_3930303_28 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000000000007339 218.0
HKD1_k127_3930303_29 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000006157 202.0
HKD1_k127_3930303_3 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 542.0
HKD1_k127_3930303_30 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000003098 203.0
HKD1_k127_3930303_31 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000004022 200.0
HKD1_k127_3930303_32 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000004464 201.0
HKD1_k127_3930303_33 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000119 194.0
HKD1_k127_3930303_34 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000006617 205.0
HKD1_k127_3930303_35 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000001368 166.0
HKD1_k127_3930303_36 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000003318 160.0
HKD1_k127_3930303_37 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.0000000000000000000000000000000001519 137.0
HKD1_k127_3930303_38 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000004264 138.0
HKD1_k127_3930303_39 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000003436 132.0
HKD1_k127_3930303_4 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 543.0
HKD1_k127_3930303_40 PHP domain protein - - - 0.00000000000000000000000003869 124.0
HKD1_k127_3930303_41 Universal bacterial protein YeaZ K14742 - - 0.000000000000000000000005917 111.0
HKD1_k127_3930303_42 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000006567 100.0
HKD1_k127_3930303_43 Phosphotransferase System K11189 - - 0.000000000000000000004544 95.0
HKD1_k127_3930303_44 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000243 88.0
HKD1_k127_3930303_45 Outer membrane lipoprotein - - - 0.00000000000006438 82.0
HKD1_k127_3930303_46 lipopolysaccharide transport K09774 - - 0.000000000001499 81.0
HKD1_k127_3930303_47 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000009306 69.0
HKD1_k127_3930303_48 Protein of unknown function (DUF465) - - - 0.00007244 48.0
HKD1_k127_3930303_49 Outer membrane lipoprotein - - - 0.00008318 53.0
HKD1_k127_3930303_5 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 516.0
HKD1_k127_3930303_50 energy transducer activity K03832,K07277 - - 0.0001986 52.0
HKD1_k127_3930303_6 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 468.0
HKD1_k127_3930303_7 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 446.0
HKD1_k127_3930303_8 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 430.0
HKD1_k127_3930303_9 Permease YjgP YjgQ family protein K07091,K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 439.0
HKD1_k127_403402_0 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 3.965e-200 638.0
HKD1_k127_403402_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 507.0
HKD1_k127_403402_10 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 303.0
HKD1_k127_403402_11 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 306.0
HKD1_k127_403402_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005259 285.0
HKD1_k127_403402_13 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004214 261.0
HKD1_k127_403402_14 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002527 264.0
HKD1_k127_403402_15 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002026 243.0
HKD1_k127_403402_16 Glycosyl transferase, family 2 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000002306 251.0
HKD1_k127_403402_17 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000000000000000000000000000004212 156.0
HKD1_k127_403402_18 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000000000000000000005197 154.0
HKD1_k127_403402_19 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000000000000000000000000000001628 145.0
HKD1_k127_403402_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 434.0
HKD1_k127_403402_20 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000002115 136.0
HKD1_k127_403402_22 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000000409 108.0
HKD1_k127_403402_23 DsrE/DsrF-like family K09004 - - 0.000000000000000007766 90.0
HKD1_k127_403402_24 Putative stress-induced transcription regulator - - - 0.00000000000000000826 92.0
HKD1_k127_403402_25 - K01992 - - 0.0000000000004753 78.0
HKD1_k127_403402_26 Beta-lactamase - - - 0.00000001489 67.0
HKD1_k127_403402_27 - - - - 0.000006076 56.0
HKD1_k127_403402_3 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 426.0
HKD1_k127_403402_4 PFAM Prenyltransferase squalene oxidase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 431.0
HKD1_k127_403402_5 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 390.0
HKD1_k127_403402_6 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 364.0
HKD1_k127_403402_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 319.0
HKD1_k127_403402_8 DNA polymerase alpha chain like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 319.0
HKD1_k127_403402_9 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 299.0
HKD1_k127_4140346_0 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 379.0
HKD1_k127_4140346_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.00000000000000000000000000000000000000000007324 162.0
HKD1_k127_4140346_3 - - - - 0.000000000000000000000000000000000000000003503 159.0
HKD1_k127_4140346_4 Las17-binding protein actin regulator - - - 0.0000000008166 61.0
HKD1_k127_4159083_0 Carboxypeptidase regulatory-like domain - - - 0.0 1152.0
HKD1_k127_4159083_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 5.017e-318 999.0
HKD1_k127_4159083_10 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 443.0
HKD1_k127_4159083_11 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 460.0
HKD1_k127_4159083_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 430.0
HKD1_k127_4159083_13 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 410.0
HKD1_k127_4159083_14 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 381.0
HKD1_k127_4159083_15 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 361.0
HKD1_k127_4159083_16 PFAM peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 364.0
HKD1_k127_4159083_17 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 331.0
HKD1_k127_4159083_18 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 313.0
HKD1_k127_4159083_19 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 292.0
HKD1_k127_4159083_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.098e-288 906.0
HKD1_k127_4159083_20 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006961 276.0
HKD1_k127_4159083_21 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002402 269.0
HKD1_k127_4159083_22 S4 RNA-binding domain K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000001033 278.0
HKD1_k127_4159083_23 transcriptional regulator K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000002739 237.0
HKD1_k127_4159083_24 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000004639 232.0
HKD1_k127_4159083_25 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000001738 219.0
HKD1_k127_4159083_26 lactoylglutathione lyase activity K03088 - - 0.0000000000000000000000000000000000000000000000000000000006325 216.0
HKD1_k127_4159083_27 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000009634 206.0
HKD1_k127_4159083_28 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000001203 203.0
HKD1_k127_4159083_29 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000372 180.0
HKD1_k127_4159083_3 ABC-type multidrug transport system ATPase and permease K06147 - - 1.256e-281 877.0
HKD1_k127_4159083_30 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000008536 179.0
HKD1_k127_4159083_31 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000006775 166.0
HKD1_k127_4159083_32 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000297 159.0
HKD1_k127_4159083_33 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000007071 146.0
HKD1_k127_4159083_34 - - - - 0.00000000000000000000000000000000041 141.0
HKD1_k127_4159083_35 BioY family K03523 - - 0.0000000000000000000000000000000009385 139.0
HKD1_k127_4159083_36 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000001224 137.0
HKD1_k127_4159083_37 protein maturation K13628 - - 0.000000000000000000000000000000001974 134.0
HKD1_k127_4159083_38 Methyltransferase type 11 - - - 0.00000000000000000000000000000004393 134.0
HKD1_k127_4159083_39 Lysin motif - - - 0.00000000000000000000000000000202 124.0
HKD1_k127_4159083_4 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.042e-244 775.0
HKD1_k127_4159083_40 AdP-ribose pyrophosphatase K01515 - 3.6.1.13 0.00000000000000000000000000004209 123.0
HKD1_k127_4159083_41 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000001063 120.0
HKD1_k127_4159083_42 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000004381 128.0
HKD1_k127_4159083_43 Protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000003346 119.0
HKD1_k127_4159083_44 Belongs to the Fur family K03711 - - 0.0000000000000000000000001423 119.0
HKD1_k127_4159083_45 Methyltransferase domain - - - 0.0000000000000000000000004976 117.0
HKD1_k127_4159083_46 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000008043 106.0
HKD1_k127_4159083_47 Domain of unknown function (DUF3597) - - - 0.0000000000000000000000377 106.0
HKD1_k127_4159083_48 Transcriptional regulator PadR-like family - - - 0.00000000000000000000008732 101.0
HKD1_k127_4159083_49 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000001174 100.0
HKD1_k127_4159083_5 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 6.999e-244 769.0
HKD1_k127_4159083_50 Transglycosylase associated protein - - - 0.000000000000000000002207 96.0
HKD1_k127_4159083_52 Domain of unknown function (DUF4399) - - - 0.00000000000000000002708 96.0
HKD1_k127_4159083_54 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000004082 88.0
HKD1_k127_4159083_55 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000008377 78.0
HKD1_k127_4159083_56 MoaE protein K03635,K03636,K03637,K03752,K21142 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.7.7.77,2.8.1.12,4.6.1.17 0.0000000000002978 80.0
HKD1_k127_4159083_57 - - - - 0.000000000005115 78.0
HKD1_k127_4159083_58 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000005134 78.0
HKD1_k127_4159083_59 Cold-shock protein K03704 - - 0.0000000001311 66.0
HKD1_k127_4159083_6 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 4.185e-228 717.0
HKD1_k127_4159083_60 Biopolymer transport K03559 - - 0.0000000006143 66.0
HKD1_k127_4159083_61 Cold shock K03704 - - 0.000000004323 61.0
HKD1_k127_4159083_62 CHAT domain - - - 0.00000001041 68.0
HKD1_k127_4159083_63 - - - - 0.00000002173 61.0
HKD1_k127_4159083_64 Tetratricopeptide repeat - - - 0.0000001867 63.0
HKD1_k127_4159083_65 Protein of unknown function (DUF2914) - - - 0.00002488 57.0
HKD1_k127_4159083_66 Putative phosphatase (DUF442) - - - 0.0005378 48.0
HKD1_k127_4159083_7 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 492.0
HKD1_k127_4159083_8 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 464.0
HKD1_k127_4159083_9 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 460.0
HKD1_k127_4184743_0 cellulose binding - - - 0.0 1242.0
HKD1_k127_4184743_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 578.0
HKD1_k127_4184743_2 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 383.0
HKD1_k127_4184743_3 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 296.0
HKD1_k127_4184743_4 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000008123 169.0
HKD1_k127_4184743_5 deaminase zinc-binding - - - 0.0000000000000000000000000000000000000000000832 164.0
HKD1_k127_4184743_6 negative regulation of translational initiation - - - 0.00000005773 61.0
HKD1_k127_4184979_0 Molybdopterin oxidoreductase - - - 0.0 1631.0
HKD1_k127_4184979_1 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1412.0
HKD1_k127_4184979_10 Acyl-coa dehydrogenase K00249 - 1.3.8.7 1.872e-198 629.0
HKD1_k127_4184979_100 Barrel-sandwich domain of CusB or HlyD membrane-fusion K07798 - - 0.00000002195 66.0
HKD1_k127_4184979_101 Protein of unknown function (DUF3341) - - - 0.000001192 57.0
HKD1_k127_4184979_102 pfam cbs - - - 0.00000157 56.0
HKD1_k127_4184979_103 calcium, potassium:sodium antiporter activity K07301 - - 0.000002107 52.0
HKD1_k127_4184979_104 - - - - 0.000002712 57.0
HKD1_k127_4184979_105 - - - - 0.00001217 53.0
HKD1_k127_4184979_106 Signal peptide protein - - - 0.00001854 55.0
HKD1_k127_4184979_107 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00002368 54.0
HKD1_k127_4184979_108 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00003419 58.0
HKD1_k127_4184979_109 metallophosphoesterase - - - 0.00003482 56.0
HKD1_k127_4184979_11 4 iron, 4 sulfur cluster binding - - - 4.71e-198 633.0
HKD1_k127_4184979_110 - - - - 0.00007813 49.0
HKD1_k127_4184979_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00371,K16965,K17048,K17051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 601.0
HKD1_k127_4184979_13 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 586.0
HKD1_k127_4184979_14 Pyrrolo-quinoline quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 588.0
HKD1_k127_4184979_15 PQQ-like domain K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 580.0
HKD1_k127_4184979_16 Baseplate J-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 558.0
HKD1_k127_4184979_17 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 547.0
HKD1_k127_4184979_18 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 521.0
HKD1_k127_4184979_19 Phage tail protein (Tail_P2_I) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 529.0
HKD1_k127_4184979_2 Domain of unknown function (DUF5117) - - - 0.0 1254.0
HKD1_k127_4184979_20 Late control gene D protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 506.0
HKD1_k127_4184979_21 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 507.0
HKD1_k127_4184979_22 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 502.0
HKD1_k127_4184979_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 493.0
HKD1_k127_4184979_24 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 494.0
HKD1_k127_4184979_25 LOR/SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 460.0
HKD1_k127_4184979_26 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 450.0
HKD1_k127_4184979_27 Phage tail sheath protein K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 424.0
HKD1_k127_4184979_28 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 439.0
HKD1_k127_4184979_29 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 395.0
HKD1_k127_4184979_3 PFAM Conserved region in glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1150.0
HKD1_k127_4184979_30 Acetyl xylan esterase (AXE1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 403.0
HKD1_k127_4184979_31 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 378.0
HKD1_k127_4184979_32 Coenzyme A transferase K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 344.0
HKD1_k127_4184979_33 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 351.0
HKD1_k127_4184979_34 Coenzyme A transferase K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 318.0
HKD1_k127_4184979_35 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 323.0
HKD1_k127_4184979_36 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 314.0
HKD1_k127_4184979_37 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 322.0
HKD1_k127_4184979_38 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 334.0
HKD1_k127_4184979_39 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 307.0
HKD1_k127_4184979_4 Baseplate J-like protein - - - 0.0 1105.0
HKD1_k127_4184979_40 Tail protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 297.0
HKD1_k127_4184979_41 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 318.0
HKD1_k127_4184979_42 Cytochrome c K00373,K00405,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 301.0
HKD1_k127_4184979_43 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000269 277.0
HKD1_k127_4184979_44 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000001242 267.0
HKD1_k127_4184979_45 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001549 274.0
HKD1_k127_4184979_46 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005069 247.0
HKD1_k127_4184979_47 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000002416 248.0
HKD1_k127_4184979_48 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000008274 256.0
HKD1_k127_4184979_49 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000002231 230.0
HKD1_k127_4184979_5 Hydrolase CocE NonD family - - - 4.487e-308 955.0
HKD1_k127_4184979_50 Protein of unknown function (DUF4255) - - - 0.0000000000000000000000000000000000000000000000000000000000003897 224.0
HKD1_k127_4184979_51 phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000004541 228.0
HKD1_k127_4184979_52 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000009825 215.0
HKD1_k127_4184979_53 - - - - 0.00000000000000000000000000000000000000000000000000000000005193 206.0
HKD1_k127_4184979_54 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000002377 204.0
HKD1_k127_4184979_55 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000003246 203.0
HKD1_k127_4184979_56 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000009668 192.0
HKD1_k127_4184979_57 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000002501 196.0
HKD1_k127_4184979_58 domain, Protein K15125 - - 0.000000000000000000000000000000000000000000000000007371 190.0
HKD1_k127_4184979_59 Rhs element vgr protein - - - 0.0000000000000000000000000000000000000000000000005908 182.0
HKD1_k127_4184979_6 Dehydrogenase K00117 - 1.1.5.2 2.312e-276 867.0
HKD1_k127_4184979_60 COG0714 MoxR-like ATPases K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000008843 183.0
HKD1_k127_4184979_61 YCII-related domain - - - 0.000000000000000000000000000000000000000000001052 169.0
HKD1_k127_4184979_62 DinB family - - - 0.00000000000000000000000000000000000000000000988 171.0
HKD1_k127_4184979_63 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000001525 160.0
HKD1_k127_4184979_64 DinB family - - - 0.0000000000000000000000000000000000000000006356 161.0
HKD1_k127_4184979_65 Damage-inducible protein DinB - - - 0.0000000000000000000000000000000000000000009315 169.0
HKD1_k127_4184979_66 PFAM Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000426 172.0
HKD1_k127_4184979_67 Gene 25-like lysozyme K06903 - - 0.000000000000000000000000000000000000000008289 162.0
HKD1_k127_4184979_68 DinB family - - - 0.000000000000000000000000000000000000002323 152.0
HKD1_k127_4184979_69 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000002953 144.0
HKD1_k127_4184979_7 metal-dependent hydrolase with the TIM-barrel fold - - - 4.747e-268 835.0
HKD1_k127_4184979_70 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000003628 160.0
HKD1_k127_4184979_72 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.000000000000000000000000000000000006491 141.0
HKD1_k127_4184979_73 shikimate kinase activity K00891,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000001055 149.0
HKD1_k127_4184979_74 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000565 137.0
HKD1_k127_4184979_75 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000389 137.0
HKD1_k127_4184979_76 PAAR motif - - - 0.000000000000000000000000000000006468 147.0
HKD1_k127_4184979_77 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000009536 133.0
HKD1_k127_4184979_78 Cytochrome c - - - 0.00000000000000000000000000000007645 129.0
HKD1_k127_4184979_79 peroxiredoxin activity K01607 - 4.1.1.44 0.000000000000000000000000008541 113.0
HKD1_k127_4184979_8 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 7.299e-239 745.0
HKD1_k127_4184979_80 DoxX-like family - - - 0.00000000000000000000000001196 113.0
HKD1_k127_4184979_81 Domain of unknown function (DUF4157) - - - 0.00000000000000000004606 106.0
HKD1_k127_4184979_82 lactoylglutathione lyase activity - - - 0.0000000000000000002291 94.0
HKD1_k127_4184979_83 Von Willebrand factor type A domain K07114 - - 0.0000000000000000006252 99.0
HKD1_k127_4184979_84 Nitrate reductase delta subunit - - - 0.000000000000000006051 95.0
HKD1_k127_4184979_85 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000002911 98.0
HKD1_k127_4184979_86 - - - - 0.00000000000000005849 93.0
HKD1_k127_4184979_87 protein transport - - - 0.00000000000000006382 83.0
HKD1_k127_4184979_88 PFAM blue (type 1) copper domain protein - - - 0.00000000000000006628 90.0
HKD1_k127_4184979_89 lipoprotein biosynthetic process - - - 0.0000000000000002926 92.0
HKD1_k127_4184979_9 PFAM peptidase - - - 4.058e-208 659.0
HKD1_k127_4184979_90 L-ascorbic acid biosynthetic process - - - 0.000000000000001214 92.0
HKD1_k127_4184979_91 - - - - 0.000000000000001443 85.0
HKD1_k127_4184979_92 - - - - 0.000000000000004593 84.0
HKD1_k127_4184979_93 - - - - 0.00000000000002278 76.0
HKD1_k127_4184979_94 Protein of unknown function DUF58 - - - 0.0000000000002695 80.0
HKD1_k127_4184979_95 von Willebrand factor, type A K07114 - - 0.000000000007551 78.0
HKD1_k127_4184979_97 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.00000000003063 73.0
HKD1_k127_4184979_98 solute binding protein K02035 - - 0.0000000154 66.0
HKD1_k127_4184979_99 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000001867 63.0
HKD1_k127_4204752_0 Flavin containing amine oxidoreductase - - - 4.781e-285 885.0
HKD1_k127_4204752_1 Peptidase dimerisation domain K12941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 550.0
HKD1_k127_4204752_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 512.0
HKD1_k127_4204752_3 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 458.0
HKD1_k127_4204752_4 transcriptional regulator - - - 0.00000000000000000000000000000000000000000417 168.0
HKD1_k127_4207354_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 4.869e-271 850.0
HKD1_k127_4207354_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 6.812e-254 807.0
HKD1_k127_4207354_10 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 504.0
HKD1_k127_4207354_11 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 518.0
HKD1_k127_4207354_12 aminopeptidase activity K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 455.0
HKD1_k127_4207354_13 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 460.0
HKD1_k127_4207354_14 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 453.0
HKD1_k127_4207354_15 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 453.0
HKD1_k127_4207354_16 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 441.0
HKD1_k127_4207354_17 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 392.0
HKD1_k127_4207354_18 SMC proteins Flexible Hinge Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 419.0
HKD1_k127_4207354_19 sulfuric ester hydrolase activity K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 387.0
HKD1_k127_4207354_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.284e-235 759.0
HKD1_k127_4207354_20 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 372.0
HKD1_k127_4207354_21 PFAM peptidase M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 353.0
HKD1_k127_4207354_22 Methyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 328.0
HKD1_k127_4207354_23 glycerol channel activity K09876,K09877,K09886,K10404 GO:0002376,GO:0003674,GO:0005215,GO:0005372,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006833,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008643,GO:0009605,GO:0009607,GO:0009617,GO:0015250,GO:0015267,GO:0015318,GO:0015791,GO:0015793,GO:0015850,GO:0016020,GO:0016323,GO:0022803,GO:0022838,GO:0022857,GO:0042044,GO:0042742,GO:0043207,GO:0044425,GO:0044459,GO:0044464,GO:0045087,GO:0050829,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0055085,GO:0071702,GO:0071944,GO:0098542,GO:0098590 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 311.0
HKD1_k127_4207354_24 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 311.0
HKD1_k127_4207354_25 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 300.0
HKD1_k127_4207354_26 beta' subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 296.0
HKD1_k127_4207354_27 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 292.0
HKD1_k127_4207354_28 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002195 288.0
HKD1_k127_4207354_29 Belongs to the LTA synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001356 298.0
HKD1_k127_4207354_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.185e-227 713.0
HKD1_k127_4207354_30 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000001879 273.0
HKD1_k127_4207354_31 NADP oxidoreductase coenzyme F420-dependent K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000008038 268.0
HKD1_k127_4207354_32 Sugar (and other) transporter K08178 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002161 260.0
HKD1_k127_4207354_33 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002567 264.0
HKD1_k127_4207354_34 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000127 254.0
HKD1_k127_4207354_35 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000002457 233.0
HKD1_k127_4207354_36 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000121 225.0
HKD1_k127_4207354_37 acr, cog1565 - - - 0.00000000000000000000000000000000000000000000000000000000000001271 231.0
HKD1_k127_4207354_38 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000008809 226.0
HKD1_k127_4207354_39 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000004293 222.0
HKD1_k127_4207354_4 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 9.057e-200 634.0
HKD1_k127_4207354_40 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000006991 213.0
HKD1_k127_4207354_41 - - - - 0.0000000000000000000000000000000000000000000000000000007867 208.0
HKD1_k127_4207354_42 Histidine kinase K02668,K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000001132 204.0
HKD1_k127_4207354_43 - - - - 0.00000000000000000000000000000000000000000000000002372 195.0
HKD1_k127_4207354_44 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000000000000000000000003691 192.0
HKD1_k127_4207354_45 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000006633 185.0
HKD1_k127_4207354_46 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000008622 157.0
HKD1_k127_4207354_47 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000002275 152.0
HKD1_k127_4207354_48 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000004862 134.0
HKD1_k127_4207354_49 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000001181 135.0
HKD1_k127_4207354_5 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 1.269e-198 629.0
HKD1_k127_4207354_50 Resolvase, N terminal domain - - - 0.0000000000000000000000000004815 123.0
HKD1_k127_4207354_51 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000007329 115.0
HKD1_k127_4207354_52 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000002047 118.0
HKD1_k127_4207354_53 Domain of unknown function (DUF4389) - - - 0.000000000000000000000001203 111.0
HKD1_k127_4207354_54 - - - - 0.000000000000000000001618 105.0
HKD1_k127_4207354_55 chlorophyll binding K03640 - - 0.0000000000000000001165 104.0
HKD1_k127_4207354_56 - - - - 0.0000000000000000003356 87.0
HKD1_k127_4207354_57 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.00000000000000004062 83.0
HKD1_k127_4207354_58 Na+/H+ antiporter 1 K03313 - - 0.0000000000000002759 92.0
HKD1_k127_4207354_59 PrcB C-terminal - - - 0.0000000000000007978 91.0
HKD1_k127_4207354_6 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 627.0
HKD1_k127_4207354_60 Protein of unknown function (DUF503) K09764 - - 0.000000000000001671 80.0
HKD1_k127_4207354_61 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000007678 66.0
HKD1_k127_4207354_63 Belongs to the 'phage' integrase family - - - 0.0000000004901 72.0
HKD1_k127_4207354_65 type IV pilus modification protein PilV K02459,K02671 - - 0.000000437 59.0
HKD1_k127_4207354_66 positive regulation of growth K19687 - - 0.000001454 62.0
HKD1_k127_4207354_67 Bacterial Ig-like domain 2 - - - 0.0003549 51.0
HKD1_k127_4207354_68 Xylose isomerase-like TIM barrel - - - 0.0004079 51.0
HKD1_k127_4207354_7 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 571.0
HKD1_k127_4207354_8 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 554.0
HKD1_k127_4207354_9 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 533.0
HKD1_k127_4254830_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 2.645e-292 927.0
HKD1_k127_4254830_1 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 8.016e-194 638.0
HKD1_k127_4254830_10 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000006342 201.0
HKD1_k127_4254830_11 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000009081 199.0
HKD1_k127_4254830_12 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000003156 186.0
HKD1_k127_4254830_13 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000001022 168.0
HKD1_k127_4254830_14 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000000000000008018 150.0
HKD1_k127_4254830_15 - - - - 0.00000000000000000000000000000000003131 143.0
HKD1_k127_4254830_16 Subtilase family - - - 0.00000000000000000000000000000001488 147.0
HKD1_k127_4254830_17 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000002416 123.0
HKD1_k127_4254830_18 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000001796 102.0
HKD1_k127_4254830_19 Protein chain release factor B K15034 - - 0.0000000000000000000002751 109.0
HKD1_k127_4254830_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 589.0
HKD1_k127_4254830_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000001515 102.0
HKD1_k127_4254830_21 negative regulation of transcription, DNA-templated - - - 0.00000000000001068 78.0
HKD1_k127_4254830_22 energy transducer activity K03832,K07126 - - 0.00000000001348 75.0
HKD1_k127_4254830_23 TadE-like protein - - - 0.0000000001167 68.0
HKD1_k127_4254830_3 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 484.0
HKD1_k127_4254830_4 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 478.0
HKD1_k127_4254830_5 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 441.0
HKD1_k127_4254830_6 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 344.0
HKD1_k127_4254830_7 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 289.0
HKD1_k127_4254830_8 PhoD-like phosphatase K01179,K21449 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004734 306.0
HKD1_k127_4254830_9 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000007148 267.0
HKD1_k127_4261029_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 535.0
HKD1_k127_4261029_1 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 462.0
HKD1_k127_4261029_2 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000009918 256.0
HKD1_k127_4261029_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000006173 133.0
HKD1_k127_4282828_0 Dienelactone hydrolase family - - - 5.296e-244 781.0
HKD1_k127_4282828_1 Amidase K01426 - 3.5.1.4 1.096e-224 709.0
HKD1_k127_4282828_10 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 477.0
HKD1_k127_4282828_11 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 450.0
HKD1_k127_4282828_12 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 411.0
HKD1_k127_4282828_13 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 392.0
HKD1_k127_4282828_14 COG2513 PEP phosphonomutase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000004922 233.0
HKD1_k127_4282828_15 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000003563 210.0
HKD1_k127_4282828_16 Methyltransferase domain - - - 0.000000000000000000000000000000000000002127 157.0
HKD1_k127_4282828_17 Collagen triple helix - - - 0.0000000000000000000000000000001841 137.0
HKD1_k127_4282828_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 609.0
HKD1_k127_4282828_3 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 574.0
HKD1_k127_4282828_4 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 543.0
HKD1_k127_4282828_5 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 525.0
HKD1_k127_4282828_6 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 505.0
HKD1_k127_4282828_7 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 477.0
HKD1_k127_4282828_8 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 493.0
HKD1_k127_4282828_9 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 476.0
HKD1_k127_4300800_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 466.0
HKD1_k127_4300800_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001687 244.0
HKD1_k127_4300800_2 Belongs to the BI1 family K19416 - - 0.00000004626 58.0
HKD1_k127_4300800_3 Resolvase, N terminal domain - - - 0.000001504 53.0
HKD1_k127_434477_0 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 1.752e-226 706.0
HKD1_k127_434477_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 1.593e-203 670.0
HKD1_k127_434477_10 - - - - 0.0000000000000000000009503 104.0
HKD1_k127_434477_11 Outer membrane protein beta-barrel domain - - - 0.00000000008065 72.0
HKD1_k127_434477_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 449.0
HKD1_k127_434477_3 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 437.0
HKD1_k127_434477_4 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 315.0
HKD1_k127_434477_5 antibiotic catabolic process K13277,K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001306 294.0
HKD1_k127_434477_6 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000006776 205.0
HKD1_k127_434477_7 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000003965 218.0
HKD1_k127_434477_8 Haem-degrading - - - 0.0000000000000000000000000000000007053 138.0
HKD1_k127_434477_9 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000001505 109.0
HKD1_k127_435310_0 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 527.0
HKD1_k127_435310_1 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 372.0
HKD1_k127_435310_2 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 346.0
HKD1_k127_435310_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001152 262.0
HKD1_k127_435310_4 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000002298 196.0
HKD1_k127_435310_5 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000000000000003054 186.0
HKD1_k127_435310_6 Bile acid - - - 0.000005481 56.0
HKD1_k127_4366437_0 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 491.0
HKD1_k127_4366437_1 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 442.0
HKD1_k127_4366437_2 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 427.0
HKD1_k127_4366437_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 295.0
HKD1_k127_4366437_4 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000005606 143.0
HKD1_k127_4366437_5 rod shape-determining protein MreD K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.00000000003182 70.0
HKD1_k127_439053_0 Sortilin, neurotensin receptor 3, - - - 0.0 1308.0
HKD1_k127_439053_1 Sortilin, neurotensin receptor 3, - - - 0.0 1251.0
HKD1_k127_439053_10 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 537.0
HKD1_k127_439053_11 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 487.0
HKD1_k127_439053_12 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 491.0
HKD1_k127_439053_13 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 463.0
HKD1_k127_439053_14 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 449.0
HKD1_k127_439053_15 kinase activity K01006,K01007,K22424 - 2.7.3.13,2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 407.0
HKD1_k127_439053_16 receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 415.0
HKD1_k127_439053_17 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 390.0
HKD1_k127_439053_18 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 376.0
HKD1_k127_439053_19 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 347.0
HKD1_k127_439053_2 cellulose binding - - - 0.0 1197.0
HKD1_k127_439053_20 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 342.0
HKD1_k127_439053_21 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 334.0
HKD1_k127_439053_22 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K14986 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 331.0
HKD1_k127_439053_23 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 322.0
HKD1_k127_439053_24 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 326.0
HKD1_k127_439053_25 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 317.0
HKD1_k127_439053_26 S-acyltransferase activity K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 295.0
HKD1_k127_439053_27 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 304.0
HKD1_k127_439053_28 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 294.0
HKD1_k127_439053_29 PFAM phosphoesterase K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000002277 241.0
HKD1_k127_439053_3 Carboxypeptidase regulatory-like domain - - - 0.0 1036.0
HKD1_k127_439053_30 Putative esterase K07017 - - 0.00000000000000000000000000000000000000000000000000000000000000000003519 240.0
HKD1_k127_439053_31 - - - - 0.0000000000000000000000000000000000000000000000000000000000003865 225.0
HKD1_k127_439053_32 imidazolonepropionase activity - - - 0.000000000000000000000000000000000000000000000000000000000001969 228.0
HKD1_k127_439053_33 acetylesterase activity K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000001009 219.0
HKD1_k127_439053_34 esterase - - - 0.000000000000000000000000000000000000000000000000000000001431 209.0
HKD1_k127_439053_35 - - - - 0.000000000000000000000000000000000000000000000004915 187.0
HKD1_k127_439053_36 Domain of unknown function (DUF3291) - - - 0.00000000000000000000000000000000000000000000007406 178.0
HKD1_k127_439053_37 protein possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000004949 160.0
HKD1_k127_439053_38 nitric oxide dioxygenase activity K17247 - - 0.000000000000000000000000000000000000001564 154.0
HKD1_k127_439053_39 Protein of unknown function, DUF481 - - - 0.000000000000000000000000000000000000007108 161.0
HKD1_k127_439053_4 cellulose binding - - - 1.861e-289 924.0
HKD1_k127_439053_40 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.0000000000000000000000000000000000005091 142.0
HKD1_k127_439053_41 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000006873 139.0
HKD1_k127_439053_42 peroxiredoxin activity - - - 0.0000000000000000000000000000000008498 138.0
HKD1_k127_439053_43 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000002594 142.0
HKD1_k127_439053_45 - - - - 0.000000000000000000000000000000008248 142.0
HKD1_k127_439053_46 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000001319 131.0
HKD1_k127_439053_47 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000000006746 124.0
HKD1_k127_439053_48 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000004531 110.0
HKD1_k127_439053_49 DsrE/DsrF-like family - - - 0.000000000000000000000002045 110.0
HKD1_k127_439053_5 efflux transmembrane transporter activity - - - 5.609e-280 882.0
HKD1_k127_439053_50 cheY-homologous receiver domain - - - 0.00000000000000000000006701 106.0
HKD1_k127_439053_51 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000001218 99.0
HKD1_k127_439053_52 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000004354 94.0
HKD1_k127_439053_53 - - - - 0.0000000000000000008096 94.0
HKD1_k127_439053_54 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000007083 88.0
HKD1_k127_439053_55 NifU-like domain - - - 0.000000000000003943 83.0
HKD1_k127_439053_57 Bile acid - - - 0.00000003955 58.0
HKD1_k127_439053_6 ATP-grasp domain K01905,K22224 - 6.2.1.13 2.229e-272 878.0
HKD1_k127_439053_7 TIGRFAM Aspartate kinase K12524 - 1.1.1.3,2.7.2.4 9.869e-209 676.0
HKD1_k127_439053_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 582.0
HKD1_k127_439053_9 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 522.0
HKD1_k127_4396451_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.168e-293 915.0
HKD1_k127_4396451_1 AAA ATPase, central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 531.0
HKD1_k127_4396451_10 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003189 276.0
HKD1_k127_4396451_11 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000006024 242.0
HKD1_k127_4396451_12 PFAM phospholipase Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000004716 242.0
HKD1_k127_4396451_13 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000001584 223.0
HKD1_k127_4396451_14 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000001834 173.0
HKD1_k127_4396451_15 - - - - 0.000000000000000000000000000000000000000000002854 168.0
HKD1_k127_4396451_16 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000000003514 166.0
HKD1_k127_4396451_17 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000237 150.0
HKD1_k127_4396451_18 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000005661 151.0
HKD1_k127_4396451_19 MlaD protein K02067 - - 0.00000000000000000000000000000000000001554 157.0
HKD1_k127_4396451_2 carbon-oxygen lyase activity, acting on polysaccharides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 519.0
HKD1_k127_4396451_20 hydroperoxide reductase activity - - - 0.00000000000000000000000000000000001683 137.0
HKD1_k127_4396451_21 hydroperoxide reductase activity - - - 0.00000000000000000000000000000000131 132.0
HKD1_k127_4396451_22 Major Facilitator Superfamily - - - 0.0000000000000000000000000000002689 128.0
HKD1_k127_4396451_23 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000003818 135.0
HKD1_k127_4396451_24 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000848 129.0
HKD1_k127_4396451_25 - - - - 0.000000000000000000003028 102.0
HKD1_k127_4396451_26 Protein of unknown function VcgC/VcgE (DUF2780) - - - 0.0000000000000006731 84.0
HKD1_k127_4396451_27 YtxH-like protein - - - 0.000000001462 64.0
HKD1_k127_4396451_28 Domain of unknown function (DUF4136) - - - 0.0000007642 61.0
HKD1_k127_4396451_29 Domain of unknown function (DUF3336) - - - 0.0002651 53.0
HKD1_k127_4396451_3 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 470.0
HKD1_k127_4396451_4 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 423.0
HKD1_k127_4396451_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 368.0
HKD1_k127_4396451_6 PFAM Acetamidase Formamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 359.0
HKD1_k127_4396451_7 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 347.0
HKD1_k127_4396451_8 Histidine kinase K07683 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 313.0
HKD1_k127_4396451_9 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001413 292.0
HKD1_k127_478280_0 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia - - - 4.161e-217 688.0
HKD1_k127_478280_1 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 523.0
HKD1_k127_478280_10 Ferritin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001785 259.0
HKD1_k127_478280_12 Belongs to the BI1 family K06890 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000002987 211.0
HKD1_k127_478280_13 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000002845 211.0
HKD1_k127_478280_14 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K13524 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000007997 196.0
HKD1_k127_478280_15 Cupin domain - - - 0.00000000000000000000000000000000001337 147.0
HKD1_k127_478280_16 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000003914 131.0
HKD1_k127_478280_17 YjbR - - - 0.0000000000000000000000000004646 115.0
HKD1_k127_478280_18 LUD domain K00782 - - 0.0000000000000000000000004654 113.0
HKD1_k127_478280_2 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 503.0
HKD1_k127_478280_20 efflux transmembrane transporter activity - - - 0.00000000000003303 75.0
HKD1_k127_478280_21 PFAM PBS lyase HEAT domain protein - - - 0.00000000001563 74.0
HKD1_k127_478280_24 Iron permease K07243 - - 0.000192 52.0
HKD1_k127_478280_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 518.0
HKD1_k127_478280_4 Alanine racemase, N-terminal domain K18425,K19967 - 4.1.2.42,4.1.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 452.0
HKD1_k127_478280_5 LUD domain K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 446.0
HKD1_k127_478280_6 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 410.0
HKD1_k127_478280_7 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 387.0
HKD1_k127_478280_8 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 297.0
HKD1_k127_478280_9 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001941 286.0
HKD1_k127_4837273_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 1.531e-212 673.0
HKD1_k127_4837273_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 6.241e-208 653.0
HKD1_k127_4837273_10 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005153 279.0
HKD1_k127_4837273_11 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000003967 256.0
HKD1_k127_4837273_12 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000000000102 243.0
HKD1_k127_4837273_13 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001042 258.0
HKD1_k127_4837273_14 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000002206 245.0
HKD1_k127_4837273_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000001958 233.0
HKD1_k127_4837273_16 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000003598 216.0
HKD1_k127_4837273_17 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000005557 211.0
HKD1_k127_4837273_18 PBS lyase HEAT-like repeat - - - 0.000000000000000000000000000000000000000000000000000000000155 221.0
HKD1_k127_4837273_19 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000162 201.0
HKD1_k127_4837273_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 452.0
HKD1_k127_4837273_20 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000002392 196.0
HKD1_k127_4837273_21 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000003254 199.0
HKD1_k127_4837273_22 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000005839 203.0
HKD1_k127_4837273_23 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000007328 148.0
HKD1_k127_4837273_24 helix_turn_helix, Arsenical Resistance Operon Repressor - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000006323 130.0
HKD1_k127_4837273_25 - - - - 0.00000000000000000000000000001457 130.0
HKD1_k127_4837273_26 Phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000002418 111.0
HKD1_k127_4837273_27 - - - - 0.000000000000000000001445 99.0
HKD1_k127_4837273_28 CHAD domain - - - 0.000000000000000003461 96.0
HKD1_k127_4837273_29 - - - - 0.000000000000003752 87.0
HKD1_k127_4837273_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 441.0
HKD1_k127_4837273_30 Phage integrase family - - - 0.00000000000006527 74.0
HKD1_k127_4837273_31 Glycosyl hydrolase family 48 - - - 0.000000000002437 80.0
HKD1_k127_4837273_32 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000004914 62.0
HKD1_k127_4837273_4 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 421.0
HKD1_k127_4837273_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 391.0
HKD1_k127_4837273_6 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 379.0
HKD1_k127_4837273_7 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 380.0
HKD1_k127_4837273_8 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009975 346.0
HKD1_k127_4837273_9 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 321.0
HKD1_k127_491942_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 3.089e-206 663.0
HKD1_k127_491942_1 Belongs to the thiolase family K00626 - 2.3.1.9 5.285e-195 615.0
HKD1_k127_491942_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 430.0
HKD1_k127_491942_11 Protein of unknown function (DUF3089) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 438.0
HKD1_k127_491942_12 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 406.0
HKD1_k127_491942_13 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 377.0
HKD1_k127_491942_14 Sphingolipid Delta4-desaturase (DES) K04712 - 1.14.18.5,1.14.19.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 335.0
HKD1_k127_491942_15 Zinc-binding dehydrogenase K00055,K00121 - 1.1.1.1,1.1.1.284,1.1.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 328.0
HKD1_k127_491942_16 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 317.0
HKD1_k127_491942_17 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001676 284.0
HKD1_k127_491942_18 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001003 245.0
HKD1_k127_491942_19 MafB19-like deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000004616 212.0
HKD1_k127_491942_2 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 519.0
HKD1_k127_491942_20 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000001342 191.0
HKD1_k127_491942_21 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000002044 198.0
HKD1_k127_491942_22 dehydratase - - - 0.000000000000000000000000000000000000000000000001189 183.0
HKD1_k127_491942_23 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000002094 188.0
HKD1_k127_491942_24 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000007062 183.0
HKD1_k127_491942_25 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000003101 157.0
HKD1_k127_491942_26 Trehalose utilisation - - - 0.000000000000000000000000000000000000009401 151.0
HKD1_k127_491942_27 Phosphotriesterase family - - - 0.000000000000000000000000000000000006021 156.0
HKD1_k127_491942_28 PFAM thioesterase superfamily protein - - - 0.00000000000000000000000000000000001062 149.0
HKD1_k127_491942_29 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000001289 147.0
HKD1_k127_491942_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 504.0
HKD1_k127_491942_30 ECF sigma factor K03088 - - 0.00000000000000001507 94.0
HKD1_k127_491942_31 Tetratricopeptide repeat - - - 0.00000000000000002401 97.0
HKD1_k127_491942_32 PFAM transposase mutator type - - - 0.00000000000001066 76.0
HKD1_k127_491942_33 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000002118 74.0
HKD1_k127_491942_34 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000008977 56.0
HKD1_k127_491942_35 - - - - 0.00001142 55.0
HKD1_k127_491942_4 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009101 500.0
HKD1_k127_491942_5 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 483.0
HKD1_k127_491942_6 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 473.0
HKD1_k127_491942_7 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 452.0
HKD1_k127_491942_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 449.0
HKD1_k127_491942_9 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 444.0
HKD1_k127_49506_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1104.0
HKD1_k127_49506_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 439.0
HKD1_k127_5058037_0 MacB-like periplasmic core domain - - - 9.308e-255 816.0
HKD1_k127_5058037_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 5.85e-244 768.0
HKD1_k127_5058037_10 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002653 285.0
HKD1_k127_5058037_11 response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000009309 209.0
HKD1_k127_5058037_12 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000000000000000003516 190.0
HKD1_k127_5058037_13 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000004064 190.0
HKD1_k127_5058037_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000001309 169.0
HKD1_k127_5058037_15 protein methyltransferase activity - - - 0.0000000000000000000000000000000000000000008021 169.0
HKD1_k127_5058037_16 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000874 118.0
HKD1_k127_5058037_17 NmrA-like family - - - 0.00000000000000000000003184 104.0
HKD1_k127_5058037_18 response to abiotic stimulus - - - 0.0000000000000000001344 100.0
HKD1_k127_5058037_19 - - - - 0.000000000000000007418 89.0
HKD1_k127_5058037_2 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 493.0
HKD1_k127_5058037_20 PFAM S23 ribosomal protein - - - 0.0000000000002213 73.0
HKD1_k127_5058037_21 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.000000000002811 77.0
HKD1_k127_5058037_23 - - - - 0.0000000001987 65.0
HKD1_k127_5058037_3 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 444.0
HKD1_k127_5058037_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 448.0
HKD1_k127_5058037_5 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 387.0
HKD1_k127_5058037_6 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 389.0
HKD1_k127_5058037_7 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 351.0
HKD1_k127_5058037_8 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 331.0
HKD1_k127_5058037_9 Dihydrodipicolinate reductase, N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 310.0
HKD1_k127_5078521_0 WD40-like Beta Propeller Repeat - - - 9.473e-215 679.0
HKD1_k127_5078521_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 466.0
HKD1_k127_5078521_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 451.0
HKD1_k127_5078521_3 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 408.0
HKD1_k127_5078521_4 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000005226 169.0
HKD1_k127_5085923_0 Urocanase C-terminal domain K01712 - 4.2.1.49 1.133e-258 807.0
HKD1_k127_5085923_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 593.0
HKD1_k127_5085923_10 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 324.0
HKD1_k127_5085923_11 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001063 290.0
HKD1_k127_5085923_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008892 281.0
HKD1_k127_5085923_13 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000002566 240.0
HKD1_k127_5085923_14 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000665 224.0
HKD1_k127_5085923_15 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000007458 210.0
HKD1_k127_5085923_16 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000003104 203.0
HKD1_k127_5085923_17 PFAM von Willebrand factor type A K07114,K12511 - - 0.0000000000000000000000000000000000000000000000003217 193.0
HKD1_k127_5085923_18 Polysaccharide export protein K01991,K20988 - - 0.000000000000000000000000000000000000000009173 174.0
HKD1_k127_5085923_19 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000001321 169.0
HKD1_k127_5085923_2 Amino acid kinase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 513.0
HKD1_k127_5085923_20 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000001806 150.0
HKD1_k127_5085923_21 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000005418 118.0
HKD1_k127_5085923_22 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000003861 112.0
HKD1_k127_5085923_23 Pectate lyase superfamily protein - - - 0.0000000000000000000000005932 120.0
HKD1_k127_5085923_25 AAA ATPase domain - - - 0.0000000000001185 83.0
HKD1_k127_5085923_26 - - - - 0.000000000001064 78.0
HKD1_k127_5085923_3 Cleaves the N-terminal amino acid of tripeptides K01258 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 497.0
HKD1_k127_5085923_4 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 504.0
HKD1_k127_5085923_5 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 478.0
HKD1_k127_5085923_6 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 469.0
HKD1_k127_5085923_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 460.0
HKD1_k127_5085923_8 Cytochrome c K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 424.0
HKD1_k127_5085923_9 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 364.0
HKD1_k127_5144704_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 507.0
HKD1_k127_5144704_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 327.0
HKD1_k127_5168141_0 Dehydrogenase K00117 - 1.1.5.2 6.026e-288 902.0
HKD1_k127_5168141_1 ABC transporter, transmembrane K18890 - - 1.758e-200 641.0
HKD1_k127_5168141_10 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 511.0
HKD1_k127_5168141_11 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 364.0
HKD1_k127_5168141_12 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 360.0
HKD1_k127_5168141_13 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 327.0
HKD1_k127_5168141_14 Oxidoreductase molybdopterin binding domain K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 316.0
HKD1_k127_5168141_15 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 302.0
HKD1_k127_5168141_16 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008891 284.0
HKD1_k127_5168141_17 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008103 269.0
HKD1_k127_5168141_18 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000004289 209.0
HKD1_k127_5168141_19 Aminotransferase class-V K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000002414 194.0
HKD1_k127_5168141_2 Carboxypeptidase regulatory-like domain - - - 1.399e-199 668.0
HKD1_k127_5168141_20 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000007802 194.0
HKD1_k127_5168141_21 Aminotransferase class-V K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000005392 191.0
HKD1_k127_5168141_22 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000003491 174.0
HKD1_k127_5168141_23 Cytochrome c - - - 0.00000000000000000000000000000000000001814 149.0
HKD1_k127_5168141_24 nuclear chromosome segregation - - - 0.000000000000000001331 97.0
HKD1_k127_5168141_26 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000001142 80.0
HKD1_k127_5168141_27 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000003234 85.0
HKD1_k127_5168141_28 3D domain - - - 0.0000000000003288 76.0
HKD1_k127_5168141_3 Carbon starvation protein K06200 - - 1.946e-197 632.0
HKD1_k127_5168141_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 649.0
HKD1_k127_5168141_5 ABC transporter, transmembrane K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 597.0
HKD1_k127_5168141_6 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 551.0
HKD1_k127_5168141_7 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 568.0
HKD1_k127_5168141_8 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 526.0
HKD1_k127_5168141_9 PFAM aminotransferase, class I K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 517.0
HKD1_k127_5187747_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 2350.0
HKD1_k127_5187747_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.228e-287 902.0
HKD1_k127_5187747_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 379.0
HKD1_k127_5187747_3 outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 337.0
HKD1_k127_5187747_4 ribonuclease inhibitor activity - - - 0.000000000000000000000000000000000000000000000000000000000001096 223.0
HKD1_k127_5187747_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.0000000000000000000000000000000000000001261 156.0
HKD1_k127_5187747_7 - - - - 0.0000009586 58.0
HKD1_k127_5223346_0 cell adhesion involved in biofilm formation - - - 1.037e-238 751.0
HKD1_k127_5280290_0 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 469.0
HKD1_k127_5280290_1 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 364.0
HKD1_k127_5280290_3 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 330.0
HKD1_k127_5280290_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000001113 171.0
HKD1_k127_5280290_5 Subtilase family - - - 0.000000000000000038 95.0
HKD1_k127_5339700_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 4.54e-259 811.0
HKD1_k127_5339700_1 Amino acid permease - - - 2.293e-254 804.0
HKD1_k127_5339700_10 Bacterial sugar transferase K03606 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 430.0
HKD1_k127_5339700_11 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 443.0
HKD1_k127_5339700_12 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 421.0
HKD1_k127_5339700_13 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 419.0
HKD1_k127_5339700_14 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671,K22345 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 404.0
HKD1_k127_5339700_15 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 391.0
HKD1_k127_5339700_16 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 394.0
HKD1_k127_5339700_17 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 375.0
HKD1_k127_5339700_18 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 376.0
HKD1_k127_5339700_19 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 371.0
HKD1_k127_5339700_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 586.0
HKD1_k127_5339700_20 sulfurtransferase activity K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 364.0
HKD1_k127_5339700_21 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 330.0
HKD1_k127_5339700_22 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 322.0
HKD1_k127_5339700_23 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 313.0
HKD1_k127_5339700_24 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009901 290.0
HKD1_k127_5339700_25 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008504 277.0
HKD1_k127_5339700_26 peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000009271 267.0
HKD1_k127_5339700_27 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000001594 260.0
HKD1_k127_5339700_28 Methyltransferase small domain K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000001277 258.0
HKD1_k127_5339700_29 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002328 249.0
HKD1_k127_5339700_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 592.0
HKD1_k127_5339700_30 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001777 248.0
HKD1_k127_5339700_31 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000392 221.0
HKD1_k127_5339700_32 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000004846 203.0
HKD1_k127_5339700_33 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000006962 191.0
HKD1_k127_5339700_34 Transporter major facilitator family protein - - - 0.00000000000000000000000000000000000000000000000005795 194.0
HKD1_k127_5339700_35 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000004971 184.0
HKD1_k127_5339700_36 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000008249 179.0
HKD1_k127_5339700_37 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000000000000000000000000001046 165.0
HKD1_k127_5339700_38 Belongs to the peptidase S11 family K01286,K07258,K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.4.16.4 0.00000000000000000000000000000000000000009429 166.0
HKD1_k127_5339700_39 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000007733 164.0
HKD1_k127_5339700_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 562.0
HKD1_k127_5339700_40 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000002434 149.0
HKD1_k127_5339700_41 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000007233 148.0
HKD1_k127_5339700_42 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000002053 132.0
HKD1_k127_5339700_43 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000003079 122.0
HKD1_k127_5339700_44 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000001771 124.0
HKD1_k127_5339700_45 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000004502 119.0
HKD1_k127_5339700_46 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000002439 107.0
HKD1_k127_5339700_47 helix_turn_helix, mercury resistance K19591,K22491 - - 0.0000000000000000002503 92.0
HKD1_k127_5339700_48 PFAM Peptidase M20 - - - 0.00000000001261 65.0
HKD1_k127_5339700_49 methyltransferase - - - 0.0000000001518 70.0
HKD1_k127_5339700_5 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 571.0
HKD1_k127_5339700_50 PFAM Methyltransferase type 11 - - - 0.000000008034 66.0
HKD1_k127_5339700_51 - - - - 0.0000009923 55.0
HKD1_k127_5339700_52 protein N-acetylglucosaminyltransferase activity K09667 GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252 2.4.1.255 0.00009226 55.0
HKD1_k127_5339700_6 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 503.0
HKD1_k127_5339700_7 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 511.0
HKD1_k127_5339700_8 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 498.0
HKD1_k127_5339700_9 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 459.0
HKD1_k127_5350114_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1674.0
HKD1_k127_5350114_1 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.0 1087.0
HKD1_k127_5350114_10 PQQ-like domain K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 552.0
HKD1_k127_5350114_11 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 544.0
HKD1_k127_5350114_12 Belongs to the AB hydrolase superfamily. MetX family K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008549 534.0
HKD1_k127_5350114_13 PFAM phosphate acetyl butaryl transferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 441.0
HKD1_k127_5350114_14 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 407.0
HKD1_k127_5350114_15 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 361.0
HKD1_k127_5350114_16 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 316.0
HKD1_k127_5350114_17 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003897 274.0
HKD1_k127_5350114_18 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005402 271.0
HKD1_k127_5350114_19 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000006961 275.0
HKD1_k127_5350114_2 MacB-like periplasmic core domain - - - 9.252e-302 950.0
HKD1_k127_5350114_20 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000001403 263.0
HKD1_k127_5350114_21 TIGRFAM rfaE bifunctional protein, domain I - - - 0.00000000000000000000000000000000000000000000000000000000000004898 233.0
HKD1_k127_5350114_22 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000001098 235.0
HKD1_k127_5350114_23 lysozyme K01185 - 3.2.1.17 0.000000000000000000000000000000000000000000000000000000000001593 214.0
HKD1_k127_5350114_24 PFAM phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000007275 213.0
HKD1_k127_5350114_25 - - - - 0.00000000000000000000000000000000000000000000000000000005046 209.0
HKD1_k127_5350114_26 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000001364 209.0
HKD1_k127_5350114_27 - - - - 0.000000000000000000000000000000000000000000000004594 184.0
HKD1_k127_5350114_28 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000001187 176.0
HKD1_k127_5350114_29 UDP-galactopyranose mutase - - - 0.00000000000000000000000000000000000002609 159.0
HKD1_k127_5350114_3 efflux transmembrane transporter activity - - - 1.248e-244 779.0
HKD1_k127_5350114_30 Putative outer membrane beta-barrel porin, MtrB/PioB K22110 - - 0.0000000000000000000000000000000000004877 161.0
HKD1_k127_5350114_31 COG2199 FOG GGDEF domain - - - 0.00000000000000000000000000000000000102 148.0
HKD1_k127_5350114_32 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000002834 145.0
HKD1_k127_5350114_33 - - - - 0.000000000000000000000003955 109.0
HKD1_k127_5350114_34 Pfam:DUF1311 - - - 0.00000000000000000000005164 109.0
HKD1_k127_5350114_35 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000000000000000131 102.0
HKD1_k127_5350114_36 Acyl-CoA synthetase (NDP forming) - - - 0.00000000000000000005682 96.0
HKD1_k127_5350114_37 - - - - 0.000000000000000005663 93.0
HKD1_k127_5350114_39 Xylose isomerase-like TIM barrel - - - 0.00000000002341 74.0
HKD1_k127_5350114_4 Dehydrogenase K00114,K17760,K20936,K21676,K22473 - 1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 625.0
HKD1_k127_5350114_40 Cytochrome c K00413 - - 0.00000002055 60.0
HKD1_k127_5350114_41 transcriptional regulators - - - 0.00000002256 58.0
HKD1_k127_5350114_43 cellulase activity - - - 0.0001105 54.0
HKD1_k127_5350114_44 Carbohydrate-selective porin, OprB family - - - 0.000703 42.0
HKD1_k127_5350114_5 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 628.0
HKD1_k127_5350114_6 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 589.0
HKD1_k127_5350114_7 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008642 605.0
HKD1_k127_5350114_8 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 552.0
HKD1_k127_5350114_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 580.0
HKD1_k127_5352103_0 lipopolysaccharide transport K22110 - - 0.0 1346.0
HKD1_k127_5352103_1 Amylo-alpha-1,6-glucosidase - - - 1.189e-250 796.0
HKD1_k127_5352103_10 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 475.0
HKD1_k127_5352103_11 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 474.0
HKD1_k127_5352103_12 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 428.0
HKD1_k127_5352103_13 SMART Phospholipid glycerol acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 421.0
HKD1_k127_5352103_14 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 394.0
HKD1_k127_5352103_15 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 371.0
HKD1_k127_5352103_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 365.0
HKD1_k127_5352103_17 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 336.0
HKD1_k127_5352103_18 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 304.0
HKD1_k127_5352103_19 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002059 281.0
HKD1_k127_5352103_2 choline dehydrogenase activity - - - 6.797e-246 780.0
HKD1_k127_5352103_20 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005905 281.0
HKD1_k127_5352103_21 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001267 271.0
HKD1_k127_5352103_22 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000003981 270.0
HKD1_k127_5352103_23 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002949 268.0
HKD1_k127_5352103_24 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000002408 222.0
HKD1_k127_5352103_25 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.0000000000000000000000000000000000000000000000000000000003694 226.0
HKD1_k127_5352103_26 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000003267 204.0
HKD1_k127_5352103_27 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000001636 207.0
HKD1_k127_5352103_28 PFAM glycosyl transferase family 9 K02841 - - 0.00000000000000000000000000000000000000000000000001181 194.0
HKD1_k127_5352103_29 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000008641 186.0
HKD1_k127_5352103_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.145e-229 723.0
HKD1_k127_5352103_30 -acetyltransferase K03826,K03827,K18816 - 2.3.1.82 0.000000000000000000000000000000000000000000000006479 176.0
HKD1_k127_5352103_31 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000002252 176.0
HKD1_k127_5352103_32 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000003593 192.0
HKD1_k127_5352103_33 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000001958 178.0
HKD1_k127_5352103_34 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.0000000000000000000000000000000000000000000002034 184.0
HKD1_k127_5352103_35 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000001624 173.0
HKD1_k127_5352103_36 YceI-like domain - - - 0.00000000000000000000000000000000000000004385 158.0
HKD1_k127_5352103_37 BlaR1 peptidase M56 - - - 0.000000000000000000000000000000000000001288 166.0
HKD1_k127_5352103_38 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000000000000000000000002546 149.0
HKD1_k127_5352103_39 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000003053 144.0
HKD1_k127_5352103_4 gluconolactonase activity K01053 - 3.1.1.17 1.222e-195 629.0
HKD1_k127_5352103_40 Penicillinase repressor - - - 0.00000000000000000000000000000000012 136.0
HKD1_k127_5352103_41 - - - - 0.00000000000000000000000000000002905 130.0
HKD1_k127_5352103_42 DoxX-like family - - - 0.0000000000000000000000000000001159 131.0
HKD1_k127_5352103_43 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000007331 121.0
HKD1_k127_5352103_44 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000001022 110.0
HKD1_k127_5352103_45 DinB family - - - 0.000000000000000000003859 104.0
HKD1_k127_5352103_46 Toxin-antitoxin system, toxin component, PIN family - - - 0.0000000000000000144 90.0
HKD1_k127_5352103_47 Preprotein translocase SecG subunit K03075 - - 0.000000000000002414 80.0
HKD1_k127_5352103_48 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000001027 81.0
HKD1_k127_5352103_49 methyltransferase activity - - - 0.0000000000001095 81.0
HKD1_k127_5352103_5 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 557.0
HKD1_k127_5352103_50 Transport and Golgi organisation 2 - - - 0.0000000000009628 78.0
HKD1_k127_5352103_52 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.0000000001415 69.0
HKD1_k127_5352103_53 Predicted membrane protein (DUF2306) - - - 0.000000001998 67.0
HKD1_k127_5352103_55 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000005779 55.0
HKD1_k127_5352103_57 Cupin 2, conserved barrel domain protein K16011 - 2.7.7.13,5.3.1.8 0.00005327 53.0
HKD1_k127_5352103_58 Redoxin - - - 0.0001067 52.0
HKD1_k127_5352103_6 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 522.0
HKD1_k127_5352103_7 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 509.0
HKD1_k127_5352103_8 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 480.0
HKD1_k127_5352103_9 Transport and Golgi organisation 2 K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 490.0
HKD1_k127_5393951_0 PFAM Type II secretion system protein E K02652 - - 2.326e-226 729.0
HKD1_k127_5393951_1 Type ii and iii secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 317.0
HKD1_k127_5393951_2 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003141 255.0
HKD1_k127_5393951_3 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000000001169 167.0
HKD1_k127_5393951_4 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000007991 126.0
HKD1_k127_5393951_5 Pilus assembly protein K02662 - - 0.000000000002164 81.0
HKD1_k127_5393951_6 - - - - 0.0000271 53.0
HKD1_k127_5393951_7 PFAM Fimbrial assembly family protein K02663 - - 0.0006609 49.0
HKD1_k127_5488246_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 1.012e-222 731.0
HKD1_k127_5488246_1 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 6.962e-214 705.0
HKD1_k127_5488246_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000001539 226.0
HKD1_k127_5488246_11 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000001082 217.0
HKD1_k127_5488246_12 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000003845 210.0
HKD1_k127_5488246_13 efflux transmembrane transporter activity K12340 - - 0.0000000000000000000000000000000000000000000000000002348 206.0
HKD1_k127_5488246_14 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000000000001325 177.0
HKD1_k127_5488246_15 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000000000000000002249 188.0
HKD1_k127_5488246_16 OmpA family K03640 - - 0.0000000000000000000000000000000000001437 145.0
HKD1_k127_5488246_17 Transposase and inactivated derivatives K07497 - - 0.000000000000000000000000000000000004569 138.0
HKD1_k127_5488246_18 Integrase core domain - - - 0.000000000000000000000000005049 115.0
HKD1_k127_5488246_19 Integrase core domain K07497 - - 0.0000000000000000002202 87.0
HKD1_k127_5488246_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007265 468.0
HKD1_k127_5488246_20 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000004347 93.0
HKD1_k127_5488246_21 23S rRNA-intervening sequence protein - - - 0.0000000000000003506 83.0
HKD1_k127_5488246_22 Amidohydrolase family - - - 0.00000000000003673 87.0
HKD1_k127_5488246_23 Y_Y_Y domain - - - 0.000000000001664 82.0
HKD1_k127_5488246_24 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.000000000002191 82.0
HKD1_k127_5488246_25 Glutaredoxin-like domain (DUF836) - - - 0.00000000001433 75.0
HKD1_k127_5488246_26 helix_turn_helix, arabinose operon control protein K07720 - - 0.0001966 52.0
HKD1_k127_5488246_3 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 377.0
HKD1_k127_5488246_4 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 340.0
HKD1_k127_5488246_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 304.0
HKD1_k127_5488246_6 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006891 256.0
HKD1_k127_5488246_7 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007417 253.0
HKD1_k127_5488246_8 Protein of unknown function (DUF2400) K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000001578 250.0
HKD1_k127_5488246_9 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000001163 227.0
HKD1_k127_5770232_0 MacB-like periplasmic core domain - - - 4.679e-313 981.0
HKD1_k127_5770232_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.287e-265 844.0
HKD1_k127_5770232_2 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 627.0
HKD1_k127_5770232_3 COG0402 Cytosine deaminase and related metal-dependent hydrolases K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 343.0
HKD1_k127_5770232_4 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000001337 243.0
HKD1_k127_5770232_5 - - - - 0.0000000000000000000000000000000000002722 148.0
HKD1_k127_5770232_6 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000001277 140.0
HKD1_k127_5770232_7 - - - - 0.00000000000000000000000000000003133 136.0
HKD1_k127_5770232_8 PFAM UspA domain protein K06149 - - 0.00000000000001868 85.0
HKD1_k127_5770232_9 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0004521 53.0
HKD1_k127_5800195_0 PFAM Amidase - - - 2.635e-269 843.0
HKD1_k127_5800195_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 566.0
HKD1_k127_5800195_10 Spore coat protein CotH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004762 264.0
HKD1_k127_5800195_11 - - - - 0.0002127 46.0
HKD1_k127_5800195_2 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 459.0
HKD1_k127_5800195_3 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 414.0
HKD1_k127_5800195_4 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01919,K01955,K03802 - 6.3.2.2,6.3.2.29,6.3.2.30,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 386.0
HKD1_k127_5800195_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 355.0
HKD1_k127_5800195_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 356.0
HKD1_k127_5800195_7 carboxylic acid catabolic process K01856,K19802 - 5.1.1.20,5.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 298.0
HKD1_k127_5800195_8 Phosphoesterase family K21302 - 3.1.3.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006894 287.0
HKD1_k127_5800195_9 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001999 263.0
HKD1_k127_5933849_0 MacB-like periplasmic core domain - - - 3.487e-300 943.0
HKD1_k127_5933849_1 Protein of unknown function (DUF1190) - - - 1.318e-290 921.0
HKD1_k127_5933849_10 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 365.0
HKD1_k127_5933849_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 362.0
HKD1_k127_5933849_12 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 348.0
HKD1_k127_5933849_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 308.0
HKD1_k127_5933849_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 299.0
HKD1_k127_5933849_16 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001242 298.0
HKD1_k127_5933849_17 Protein of unknown function (DUF1698) K15257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001738 269.0
HKD1_k127_5933849_18 Fe-S oxidoreductase K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000001488 233.0
HKD1_k127_5933849_19 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001496 244.0
HKD1_k127_5933849_2 UvrD/REP helicase N-terminal domain - - - 1.066e-275 906.0
HKD1_k127_5933849_20 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000002698 231.0
HKD1_k127_5933849_21 phosphinothricin N-acetyltransferase activity K03823,K03892,K05793 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000144 193.0
HKD1_k127_5933849_22 PFAM Glycosyl transferase, group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000004554 202.0
HKD1_k127_5933849_23 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000003671 173.0
HKD1_k127_5933849_24 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000001535 166.0
HKD1_k127_5933849_25 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.0000000000000000000000000000000000000001248 165.0
HKD1_k127_5933849_26 iron ion binding - - - 0.00000000000000000000000000000000000007938 150.0
HKD1_k127_5933849_27 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000001541 150.0
HKD1_k127_5933849_28 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000001885 143.0
HKD1_k127_5933849_29 YCII-related domain K09780 - - 0.000000000000000000000004866 119.0
HKD1_k127_5933849_3 Prolyl oligopeptidase family K01303 - 3.4.19.1 3.239e-251 793.0
HKD1_k127_5933849_30 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000008283 104.0
HKD1_k127_5933849_31 PAP2 superfamily - - - 0.00000000000000000000004869 108.0
HKD1_k127_5933849_32 - - - - 0.000000000000000000004332 106.0
HKD1_k127_5933849_33 integral membrane protein - - - 0.000000000000524 78.0
HKD1_k127_5933849_34 cellulase activity - - - 0.00002322 55.0
HKD1_k127_5933849_35 Lysylphosphatidylglycerol synthase TM region - - - 0.0003034 52.0
HKD1_k127_5933849_36 collagen metabolic process - - - 0.0009022 49.0
HKD1_k127_5933849_4 Protein of unknown function (DUF1595) - - - 7.424e-248 792.0
HKD1_k127_5933849_5 PD-(D/E)XK nuclease superfamily - - - 5.225e-234 762.0
HKD1_k127_5933849_6 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 597.0
HKD1_k127_5933849_7 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 491.0
HKD1_k127_5933849_8 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 421.0
HKD1_k127_5933849_9 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 372.0
HKD1_k127_596239_0 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 6.44e-313 980.0
HKD1_k127_596239_1 peptidyl-tyrosine sulfation K01277 - 3.4.14.4 1.925e-269 843.0
HKD1_k127_596239_10 Protein of unknown function (DUF3224) - - - 0.000000000000000000000000000000000000000001202 169.0
HKD1_k127_596239_11 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000004779 164.0
HKD1_k127_596239_12 - - - - 0.00000000000000000000000006239 120.0
HKD1_k127_596239_13 YjbR - - - 0.0000000000000000000002635 102.0
HKD1_k127_596239_2 enterobactin catabolic process - - - 4.699e-213 676.0
HKD1_k127_596239_3 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 466.0
HKD1_k127_596239_4 PFAM Molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 454.0
HKD1_k127_596239_5 2Fe-2S -binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 293.0
HKD1_k127_596239_6 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006072 263.0
HKD1_k127_596239_7 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000005706 250.0
HKD1_k127_596239_8 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000003986 246.0
HKD1_k127_596239_9 - - - - 0.000000000000000000000000000000000000000000000000001477 188.0
HKD1_k127_5967868_0 Dehydrogenase K00117 - 1.1.5.2 7.987e-300 934.0
HKD1_k127_5967868_1 Response regulator receiver - - - 2.983e-201 639.0
HKD1_k127_5967868_10 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 317.0
HKD1_k127_5967868_11 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 312.0
HKD1_k127_5967868_12 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000705 241.0
HKD1_k127_5967868_13 Export-related chaperone CsaA K06878 GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000004497 166.0
HKD1_k127_5967868_14 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000001248 151.0
HKD1_k127_5967868_15 Haem-degrading - - - 0.0000000000000000000000000000000008663 141.0
HKD1_k127_5967868_16 MerR, DNA binding - - - 0.000000000000000000000000002248 116.0
HKD1_k127_5967868_17 Histidine kinase - - - 0.000000000000000000002686 100.0
HKD1_k127_5967868_18 cheY-homologous receiver domain - - - 0.0000000000000000007532 91.0
HKD1_k127_5967868_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 507.0
HKD1_k127_5967868_3 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 456.0
HKD1_k127_5967868_4 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 451.0
HKD1_k127_5967868_5 Molybdenum Cofactor Synthesis C K03639 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 422.0
HKD1_k127_5967868_6 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 372.0
HKD1_k127_5967868_7 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 377.0
HKD1_k127_5967868_8 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 357.0
HKD1_k127_5967868_9 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 331.0
HKD1_k127_6079142_0 cellulose binding - - - 0.0 1352.0
HKD1_k127_6079142_1 AcrB/AcrD/AcrF family - - - 0.0 1123.0
HKD1_k127_6079142_10 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 511.0
HKD1_k127_6079142_11 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 512.0
HKD1_k127_6079142_12 Protein of unknown function (DUF917) K09703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 499.0
HKD1_k127_6079142_13 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 381.0
HKD1_k127_6079142_14 NAD binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 317.0
HKD1_k127_6079142_15 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 292.0
HKD1_k127_6079142_16 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003241 270.0
HKD1_k127_6079142_17 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003384 252.0
HKD1_k127_6079142_18 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003397 263.0
HKD1_k127_6079142_19 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000278 266.0
HKD1_k127_6079142_2 E1-E2 ATPase K01535 - 3.6.3.6 8.171e-285 904.0
HKD1_k127_6079142_20 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009425 251.0
HKD1_k127_6079142_21 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004976 254.0
HKD1_k127_6079142_22 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008954 244.0
HKD1_k127_6079142_23 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000006284 251.0
HKD1_k127_6079142_24 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000002599 241.0
HKD1_k127_6079142_25 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000004786 216.0
HKD1_k127_6079142_26 membrane - - - 0.0000000000000000000000000000000000000000000000000000001297 203.0
HKD1_k127_6079142_27 - - - - 0.000000000000000000000000000000000000000000000001713 186.0
HKD1_k127_6079142_28 redox protein, regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000000000000208 171.0
HKD1_k127_6079142_29 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000249 179.0
HKD1_k127_6079142_3 Insulinase (Peptidase family M16) K07263 - - 6.014e-213 694.0
HKD1_k127_6079142_30 AroM protein K14591 - - 0.00000000000000000000000000000000000000000003029 169.0
HKD1_k127_6079142_31 Cupin 2, conserved barrel domain protein K07155 - 1.13.11.24 0.00000000000000000000000000000000000000000003346 166.0
HKD1_k127_6079142_32 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000005722 172.0
HKD1_k127_6079142_33 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000001279 162.0
HKD1_k127_6079142_34 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000002665 160.0
HKD1_k127_6079142_35 Universal stress protein family - - - 0.0000000000000000000000000000000000000006073 156.0
HKD1_k127_6079142_36 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000002308 146.0
HKD1_k127_6079142_37 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000006729 142.0
HKD1_k127_6079142_38 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000001431 130.0
HKD1_k127_6079142_39 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000006419 117.0
HKD1_k127_6079142_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 9.762e-195 623.0
HKD1_k127_6079142_40 Protein of unknown function (DUF1698) K15257 - - 0.0000000000000000000000001007 117.0
HKD1_k127_6079142_41 Outer membrane efflux protein - - - 0.000000000000000000000006591 116.0
HKD1_k127_6079142_42 - - - - 0.0000000000000000000000248 107.0
HKD1_k127_6079142_43 - - - - 0.000000000000000000009171 97.0
HKD1_k127_6079142_44 Dehydrogenase K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 0.0000000000000004143 83.0
HKD1_k127_6079142_45 Protein of unknown function (DUF2892) - - - 0.0000000000001037 82.0
HKD1_k127_6079142_46 AMP binding - - - 0.0000000003693 70.0
HKD1_k127_6079142_47 Putative zinc-finger - - - 0.000005866 54.0
HKD1_k127_6079142_5 Sugar (and other) transporter K03761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 618.0
HKD1_k127_6079142_6 pyridine nucleotide-disulphide oxidoreductase K17218 GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0042802,GO:0044237,GO:0045333,GO:0055114 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 589.0
HKD1_k127_6079142_7 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 567.0
HKD1_k127_6079142_8 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 551.0
HKD1_k127_6079142_9 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 529.0
HKD1_k127_6102892_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 428.0
HKD1_k127_6102892_1 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000007202 155.0
HKD1_k127_6102892_2 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000001267 157.0
HKD1_k127_6110497_0 CoA-substrate-specific enzyme activase - - - 0.0 1697.0
HKD1_k127_6110497_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 381.0
HKD1_k127_6110497_2 - - - - 0.0000000000000000000000000000000000000000000000000000001203 214.0
HKD1_k127_6110497_3 alpha amylase, catalytic region - - - 0.0000000000000000000000000000000007154 132.0
HKD1_k127_6110497_4 alpha beta - - - 0.00000000000000001358 96.0
HKD1_k127_6115666_0 radical SAM domain protein - - - 1.717e-208 664.0
HKD1_k127_6115666_1 efflux transmembrane transporter activity - - - 2.177e-197 643.0
HKD1_k127_6115666_10 ETC complex I subunit K00329 - 1.6.5.3 0.000003537 50.0
HKD1_k127_6115666_2 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 409.0
HKD1_k127_6115666_3 aldehyde oxidase K03520,K11177 - 1.17.1.4,1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 372.0
HKD1_k127_6115666_4 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 295.0
HKD1_k127_6115666_5 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000004391 269.0
HKD1_k127_6115666_6 Beta-lactamase superfamily domain K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000003432 243.0
HKD1_k127_6115666_7 [2Fe-2S] binding domain K07302,K13483 - 1.3.99.16 0.0000000000000000000000000000000000000000000001095 194.0
HKD1_k127_6115666_8 TonB dependent receptor - - - 0.0000000000000000004005 102.0
HKD1_k127_6115666_9 TonB-dependent Receptor Plug Domain - - - 0.000000000004484 74.0
HKD1_k127_6126050_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 9.799e-257 803.0
HKD1_k127_6126050_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 6.26e-203 636.0
HKD1_k127_6126050_10 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000005377 172.0
HKD1_k127_6126050_11 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000003559 157.0
HKD1_k127_6126050_12 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000008368 124.0
HKD1_k127_6126050_13 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000002048 88.0
HKD1_k127_6126050_14 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000007699 56.0
HKD1_k127_6126050_15 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000004037 55.0
HKD1_k127_6126050_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 477.0
HKD1_k127_6126050_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 317.0
HKD1_k127_6126050_4 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 320.0
HKD1_k127_6126050_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001693 288.0
HKD1_k127_6126050_6 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001271 247.0
HKD1_k127_6126050_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000009573 203.0
HKD1_k127_6126050_8 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000001232 205.0
HKD1_k127_6126050_9 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000007113 174.0
HKD1_k127_6139239_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1230.0
HKD1_k127_6139239_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1183.0
HKD1_k127_6139239_10 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 447.0
HKD1_k127_6139239_11 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 378.0
HKD1_k127_6139239_12 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 371.0
HKD1_k127_6139239_13 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 363.0
HKD1_k127_6139239_14 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 312.0
HKD1_k127_6139239_15 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 299.0
HKD1_k127_6139239_16 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 292.0
HKD1_k127_6139239_17 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009587 277.0
HKD1_k127_6139239_18 surface antigen variable number - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007382 298.0
HKD1_k127_6139239_19 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003224 263.0
HKD1_k127_6139239_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 8.581e-258 820.0
HKD1_k127_6139239_20 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000167 263.0
HKD1_k127_6139239_21 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000223 244.0
HKD1_k127_6139239_22 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000002293 225.0
HKD1_k127_6139239_23 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000002221 240.0
HKD1_k127_6139239_24 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000004917 212.0
HKD1_k127_6139239_25 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000008492 219.0
HKD1_k127_6139239_26 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000001275 168.0
HKD1_k127_6139239_27 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000001392 145.0
HKD1_k127_6139239_28 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K01488 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034355,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.5.4.4 0.000000000000000000000000000000000006634 145.0
HKD1_k127_6139239_29 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000001751 130.0
HKD1_k127_6139239_3 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.321e-251 783.0
HKD1_k127_6139239_30 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000006123 130.0
HKD1_k127_6139239_31 thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000001368 128.0
HKD1_k127_6139239_32 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000001942 119.0
HKD1_k127_6139239_33 - - - - 0.0000000000000000000000000002064 117.0
HKD1_k127_6139239_34 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000001932 111.0
HKD1_k127_6139239_35 Sigma-54 interaction domain - - - 0.0000000000000000000006689 102.0
HKD1_k127_6139239_36 Biotin-requiring enzyme - - - 0.000000000000000000001113 100.0
HKD1_k127_6139239_38 Radical SAM superfamily - - - 0.0000000000000000003382 102.0
HKD1_k127_6139239_39 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000002001 85.0
HKD1_k127_6139239_4 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.552e-201 635.0
HKD1_k127_6139239_40 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000006096 69.0
HKD1_k127_6139239_42 cellulase activity - - - 0.000000004708 68.0
HKD1_k127_6139239_43 TIGRFAM amino acid adenylation domain - - - 0.0000000127 68.0
HKD1_k127_6139239_44 CAAX amino terminal protease family - - - 0.00000008219 62.0
HKD1_k127_6139239_45 Putative zinc-finger - - - 0.00001091 57.0
HKD1_k127_6139239_5 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 621.0
HKD1_k127_6139239_6 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 593.0
HKD1_k127_6139239_7 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 520.0
HKD1_k127_6139239_8 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 518.0
HKD1_k127_6139239_9 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 505.0
HKD1_k127_6152403_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 519.0
HKD1_k127_6152403_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 372.0
HKD1_k127_6152403_2 response to oxidative stress K08368 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000002386 222.0
HKD1_k127_6152403_3 - - - - 0.00000000000000000000000000000000000000000000000000000001081 203.0
HKD1_k127_6152403_4 - - - - 0.00000000000000000000000000000000000000000000000000001802 199.0
HKD1_k127_6152403_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000327 111.0
HKD1_k127_6152403_6 Predicted membrane protein (DUF2214) K08983 - - 0.00000000000000002647 87.0
HKD1_k127_6160698_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 1.994e-246 773.0
HKD1_k127_6160698_1 Aldehyde dehydrogenase family K00138 - - 1.065e-241 775.0
HKD1_k127_6160698_10 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000257 293.0
HKD1_k127_6160698_11 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004145 291.0
HKD1_k127_6160698_12 type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000001082 232.0
HKD1_k127_6160698_13 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000001369 222.0
HKD1_k127_6160698_14 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000000000000000000000000000000000000000006808 223.0
HKD1_k127_6160698_15 PFAM helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000008442 233.0
HKD1_k127_6160698_16 DinB family - - - 0.000000000000000000000000000000000000000000000000000001888 209.0
HKD1_k127_6160698_17 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000004588 207.0
HKD1_k127_6160698_18 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000006452 188.0
HKD1_k127_6160698_19 Response regulator, receiver K02282 - - 0.000000000000000000000000000000000000000000000729 181.0
HKD1_k127_6160698_2 PFAM type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 552.0
HKD1_k127_6160698_20 TIGRFAM Flp pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000000000000000001641 173.0
HKD1_k127_6160698_21 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000006689 159.0
HKD1_k127_6160698_22 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000001001 132.0
HKD1_k127_6160698_23 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000001079 122.0
HKD1_k127_6160698_24 Smr domain - - - 0.0000000000000000001096 93.0
HKD1_k127_6160698_25 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000007525 91.0
HKD1_k127_6160698_27 regulation of translation K03530 - - 0.000000000000000006385 90.0
HKD1_k127_6160698_28 Type IV leader peptidase family K02278 - 3.4.23.43 0.000000000001169 75.0
HKD1_k127_6160698_29 - - - - 0.00007088 48.0
HKD1_k127_6160698_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 531.0
HKD1_k127_6160698_30 Flp Fap pilin component K02651 - - 0.0001727 48.0
HKD1_k127_6160698_31 Flp Fap pilin component K02651 - - 0.0005298 45.0
HKD1_k127_6160698_4 ATPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 425.0
HKD1_k127_6160698_5 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 418.0
HKD1_k127_6160698_6 DNA modification - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 361.0
HKD1_k127_6160698_7 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 313.0
HKD1_k127_6160698_8 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 319.0
HKD1_k127_6160698_9 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 309.0
HKD1_k127_6161512_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 320.0
HKD1_k127_6161512_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000003845 55.0
HKD1_k127_6171313_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 541.0
HKD1_k127_6171313_1 cell shape determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 496.0
HKD1_k127_6171313_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 442.0
HKD1_k127_6171313_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000392 263.0
HKD1_k127_6171313_4 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000000000003793 171.0
HKD1_k127_6171313_5 WYL domain K13572 - - 0.0000000000000000000000000000000000000002349 173.0
HKD1_k127_6171313_6 - - - - 0.0000003189 59.0
HKD1_k127_6184413_0 Dehydrogenase E1 component K11381 - 1.2.4.4 5.543e-267 839.0
HKD1_k127_6184413_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 3.237e-215 699.0
HKD1_k127_6184413_10 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 500.0
HKD1_k127_6184413_11 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 512.0
HKD1_k127_6184413_12 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 485.0
HKD1_k127_6184413_13 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 487.0
HKD1_k127_6184413_14 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 456.0
HKD1_k127_6184413_15 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 446.0
HKD1_k127_6184413_16 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 438.0
HKD1_k127_6184413_17 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 435.0
HKD1_k127_6184413_18 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 437.0
HKD1_k127_6184413_19 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 424.0
HKD1_k127_6184413_2 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 608.0
HKD1_k127_6184413_20 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 402.0
HKD1_k127_6184413_21 3-demethylubiquinone-9 3-O-methyltransferase activity K07011,K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 394.0
HKD1_k127_6184413_22 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 407.0
HKD1_k127_6184413_23 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 370.0
HKD1_k127_6184413_24 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 367.0
HKD1_k127_6184413_25 tRNA thio-modification K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 359.0
HKD1_k127_6184413_26 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 353.0
HKD1_k127_6184413_27 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 338.0
HKD1_k127_6184413_28 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 342.0
HKD1_k127_6184413_29 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 349.0
HKD1_k127_6184413_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 608.0
HKD1_k127_6184413_30 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 336.0
HKD1_k127_6184413_31 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 337.0
HKD1_k127_6184413_32 FES K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 312.0
HKD1_k127_6184413_33 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 317.0
HKD1_k127_6184413_34 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 332.0
HKD1_k127_6184413_35 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 317.0
HKD1_k127_6184413_36 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000596 288.0
HKD1_k127_6184413_37 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002843 310.0
HKD1_k127_6184413_38 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001524 262.0
HKD1_k127_6184413_39 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000001232 241.0
HKD1_k127_6184413_4 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 566.0
HKD1_k127_6184413_40 succinate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004842 242.0
HKD1_k127_6184413_41 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000007243 234.0
HKD1_k127_6184413_42 Squalene/phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000000000000001636 233.0
HKD1_k127_6184413_43 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000005042 228.0
HKD1_k127_6184413_44 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000001724 233.0
HKD1_k127_6184413_45 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000001923 236.0
HKD1_k127_6184413_46 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000003261 217.0
HKD1_k127_6184413_47 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000657 218.0
HKD1_k127_6184413_48 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000001665 221.0
HKD1_k127_6184413_49 GDP-mannose mannosyl hydrolase activity K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000005006 196.0
HKD1_k127_6184413_5 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 574.0
HKD1_k127_6184413_50 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000008758 192.0
HKD1_k127_6184413_51 COGs COG2912 conserved - - - 0.000000000000000000000000000000000000000000000000001139 195.0
HKD1_k127_6184413_52 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000003364 185.0
HKD1_k127_6184413_53 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000005089 192.0
HKD1_k127_6184413_54 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000002081 177.0
HKD1_k127_6184413_55 PFAM Rhomboid family - - - 0.000000000000000000000000000000000000000000001228 175.0
HKD1_k127_6184413_56 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000001784 173.0
HKD1_k127_6184413_57 WD40-like Beta Propeller - - - 0.00000000000000000000000000000000000000000004117 173.0
HKD1_k127_6184413_58 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.0000000000000000000000000000000000000000003408 175.0
HKD1_k127_6184413_59 YsiA-like protein, C-terminal region K13770 - - 0.0000000000000000000000000000000000000000003671 165.0
HKD1_k127_6184413_6 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 533.0
HKD1_k127_6184413_60 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000002543 162.0
HKD1_k127_6184413_61 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000004324 171.0
HKD1_k127_6184413_62 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000004863 155.0
HKD1_k127_6184413_63 Dienelactone hydrolase family K07018 - - 0.00000000000000000000000000000000000002527 156.0
HKD1_k127_6184413_64 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000003271 153.0
HKD1_k127_6184413_65 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000001236 144.0
HKD1_k127_6184413_66 Cupin domain - - - 0.00000000000000000000000000000000002539 141.0
HKD1_k127_6184413_67 Reverse transcriptase-like K03469 - 3.1.26.4 0.0000000000000000000000000000000561 138.0
HKD1_k127_6184413_68 Yqey-like protein K09117 - - 0.0000000000000000000000000000002043 129.0
HKD1_k127_6184413_69 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000001165 129.0
HKD1_k127_6184413_7 Pyrrolo-quinoline quinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 526.0
HKD1_k127_6184413_70 PFAM thioesterase superfamily protein K07107 - - 0.00000000000000000000000000007953 121.0
HKD1_k127_6184413_71 amine dehydrogenase activity K17285 - - 0.000000000000000000000000000274 121.0
HKD1_k127_6184413_72 Cytochrome c - - - 0.000000000000000000000000002254 118.0
HKD1_k127_6184413_73 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000003961 118.0
HKD1_k127_6184413_74 nUDIX hydrolase K03574,K03575 - 3.6.1.55 0.000000000000000000000001506 112.0
HKD1_k127_6184413_75 ABC-2 family transporter protein - - - 0.000000000000000000000003311 114.0
HKD1_k127_6184413_76 Serine aminopeptidase, S33 - - - 0.00000000000000000001998 107.0
HKD1_k127_6184413_77 Response regulator, receiver - - - 0.00000000000000000005351 94.0
HKD1_k127_6184413_78 56kDa selenium binding protein (SBP56) K17285 - - 0.000000000000004102 78.0
HKD1_k127_6184413_79 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000005481 84.0
HKD1_k127_6184413_8 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 506.0
HKD1_k127_6184413_80 Glutaredoxin K03676 - - 0.0000000000008182 74.0
HKD1_k127_6184413_81 (FHA) domain - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.00000000001523 70.0
HKD1_k127_6184413_82 PFAM HhH-GPD family protein K10773 - 4.2.99.18 0.00000001805 64.0
HKD1_k127_6184413_83 Receptor - - - 0.00000002156 66.0
HKD1_k127_6184413_84 Evidence 5 No homology to any previously reported sequences - - - 0.000001012 55.0
HKD1_k127_6184413_85 DoxX K16937 - 1.8.5.2 0.0002915 49.0
HKD1_k127_6184413_9 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 497.0
HKD1_k127_6201745_1 Outer membrane protein, OMP85 family K07277 - - 0.000001518 60.0
HKD1_k127_6216953_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02674 - - 0.0 1035.0
HKD1_k127_6216953_1 TIGRFAM Diguanylate cyclase K13590 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000003111 232.0
HKD1_k127_6216953_2 type 4 fimbrial biogenesis transmembrane K02672 - - 0.000000000000000000000000000000000000000000000006438 180.0
HKD1_k127_6216953_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.00000000000000000000000000000000000000000003844 169.0
HKD1_k127_6216953_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K08084 - - 0.00000000000000000000000000000000000003613 153.0
HKD1_k127_6216953_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02671 - - 0.00000000000000000000000000000006231 136.0
HKD1_k127_6216953_6 type-4 fimbrial biogenesis transmembrane K02673 - - 0.000000000000000000000000000008787 126.0
HKD1_k127_6216953_7 pilus assembly protein PilE K02655 - - 0.00000000000000000000000002397 119.0
HKD1_k127_6216953_8 - - - - 0.0000000000000002212 84.0
HKD1_k127_6266235_0 Domain of unknown function (DUF1998) K06877 - - 4.105e-257 820.0
HKD1_k127_6266235_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.812e-224 702.0
HKD1_k127_6266235_10 DinB family - - - 0.0000000000000000000000000000009598 129.0
HKD1_k127_6266235_11 Ferrous iron transport protein B K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000001143 130.0
HKD1_k127_6266235_12 Binds the 23S rRNA K02909 - - 0.000000000000000000000000001634 113.0
HKD1_k127_6266235_13 transcriptional regulator PadR family - - - 0.000000000000000000000000002218 115.0
HKD1_k127_6266235_14 PA14 K08738 - - 0.0000000000000001732 94.0
HKD1_k127_6266235_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 591.0
HKD1_k127_6266235_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 515.0
HKD1_k127_6266235_4 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 447.0
HKD1_k127_6266235_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000106 282.0
HKD1_k127_6266235_6 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000001068 223.0
HKD1_k127_6266235_7 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000001822 206.0
HKD1_k127_6266235_8 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000161 193.0
HKD1_k127_6266235_9 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000961 138.0
HKD1_k127_6268596_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1403.0
HKD1_k127_6268596_1 Zinc carboxypeptidase - - - 8.886e-280 879.0
HKD1_k127_6268596_2 PQQ enzyme repeat K00117 - 1.1.5.2 9.144e-270 840.0
HKD1_k127_6268596_3 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 420.0
HKD1_k127_6268596_4 PFAM Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 399.0
HKD1_k127_6268596_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 362.0
HKD1_k127_6268596_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 308.0
HKD1_k127_6268596_7 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000274 270.0
HKD1_k127_6268596_8 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000000001168 148.0
HKD1_k127_6268596_9 acr, cog1993 K09137 - - 0.000000000000000000000000000000008115 134.0
HKD1_k127_6298273_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1377.0
HKD1_k127_6298273_1 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 517.0
HKD1_k127_6298273_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 413.0
HKD1_k127_6298273_3 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004668 280.0
HKD1_k127_6298273_4 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000005103 249.0
HKD1_k127_6335337_0 metallocarboxypeptidase activity - - - 4.844e-224 747.0
HKD1_k127_6335337_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.253e-204 642.0
HKD1_k127_6335337_10 Pyridoxal-phosphate dependent enzyme K12339,K21148 - 2.5.1.113,2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 407.0
HKD1_k127_6335337_11 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 398.0
HKD1_k127_6335337_12 Deoxyhypusine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 391.0
HKD1_k127_6335337_13 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 357.0
HKD1_k127_6335337_14 Aminotransferase class-V K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 347.0
HKD1_k127_6335337_15 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 334.0
HKD1_k127_6335337_16 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 302.0
HKD1_k127_6335337_17 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 303.0
HKD1_k127_6335337_18 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 299.0
HKD1_k127_6335337_19 LamB/YcsF family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 291.0
HKD1_k127_6335337_2 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 608.0
HKD1_k127_6335337_20 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 308.0
HKD1_k127_6335337_21 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001367 285.0
HKD1_k127_6335337_22 Sigma-54 factor interaction domain-containing protein K02481,K07712,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003309 289.0
HKD1_k127_6335337_23 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002384 277.0
HKD1_k127_6335337_24 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000001357 244.0
HKD1_k127_6335337_25 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000001028 229.0
HKD1_k127_6335337_26 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000658 232.0
HKD1_k127_6335337_27 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000005226 233.0
HKD1_k127_6335337_28 unfolded protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000001255 229.0
HKD1_k127_6335337_29 iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000000000000258 221.0
HKD1_k127_6335337_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 606.0
HKD1_k127_6335337_30 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000001348 203.0
HKD1_k127_6335337_31 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000008353 194.0
HKD1_k127_6335337_32 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000001813 184.0
HKD1_k127_6335337_33 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000005587 173.0
HKD1_k127_6335337_34 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000001996 176.0
HKD1_k127_6335337_35 Cupin - - - 0.0000000000000000000000000000000000000000000004446 173.0
HKD1_k127_6335337_36 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000006925 168.0
HKD1_k127_6335337_37 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000004317 167.0
HKD1_k127_6335337_38 Transcriptional regulator - - - 0.00000000000000000000000000000000000008161 148.0
HKD1_k127_6335337_39 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000004091 139.0
HKD1_k127_6335337_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 526.0
HKD1_k127_6335337_40 JAB/MPN domain - - - 0.000000000000000000000000000000001165 135.0
HKD1_k127_6335337_41 methyltransferase activity - - - 0.0000000000000000000000000004394 123.0
HKD1_k127_6335337_42 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000004881 116.0
HKD1_k127_6335337_43 Oxidoreductase FAD-binding domain protein - - - 0.0000000000000000000000000009716 121.0
HKD1_k127_6335337_44 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000776 116.0
HKD1_k127_6335337_45 - - - - 0.00000000000000000000000003147 113.0
HKD1_k127_6335337_46 DNA-sulfur modification-associated - - - 0.00000000000000000007034 102.0
HKD1_k127_6335337_47 Acetyltransferase (GNAT) family K00619 - 2.3.1.1 0.0000000000000000001388 97.0
HKD1_k127_6335337_48 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000007148 68.0
HKD1_k127_6335337_49 Protein of unknown function (DUF541) K09807 - - 0.0000000006405 71.0
HKD1_k127_6335337_5 metallocarboxypeptidase activity K14054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 484.0
HKD1_k127_6335337_50 Putative adhesin - - - 0.000005709 57.0
HKD1_k127_6335337_52 - - - - 0.0001006 53.0
HKD1_k127_6335337_53 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K06191 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009893,GO:0009987,GO:0016491,GO:0019222,GO:0019725,GO:0022900,GO:0042592,GO:0043085,GO:0044093,GO:0044237,GO:0045454,GO:0048518,GO:0050789,GO:0050790,GO:0050794,GO:0051341,GO:0051353,GO:0055114,GO:0065007,GO:0065008,GO:0065009 - 0.0007961 44.0
HKD1_k127_6335337_6 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 475.0
HKD1_k127_6335337_7 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 493.0
HKD1_k127_6335337_8 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 449.0
HKD1_k127_6335337_9 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 419.0
HKD1_k127_6408411_0 Lanthionine synthetase C-like protein - - - 2.084e-218 708.0
HKD1_k127_6408411_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002199 292.0
HKD1_k127_6408411_2 - - - - 0.0000000000000000000000000000006625 139.0
HKD1_k127_6408411_4 TIGRFAM type VI secretion system effector, Hcp1 family K11903 - - 0.0000005564 55.0
HKD1_k127_6414531_0 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002215 276.0
HKD1_k127_6414531_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000003556 215.0
HKD1_k127_6414531_2 - - - - 0.00000000000000000000816 97.0
HKD1_k127_6436521_0 xanthine dehydrogenase activity - - - 4.957e-314 975.0
HKD1_k127_6436521_1 N-acetyldiaminopimelate deacetylase activity K12941 - - 8.722e-248 779.0
HKD1_k127_6436521_10 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 501.0
HKD1_k127_6436521_11 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 496.0
HKD1_k127_6436521_12 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 491.0
HKD1_k127_6436521_13 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 481.0
HKD1_k127_6436521_14 Cysteine-rich domain K11473 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 479.0
HKD1_k127_6436521_15 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 475.0
HKD1_k127_6436521_16 Type I phosphodiesterase / nucleotide pyrophosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 405.0
HKD1_k127_6436521_17 Dihydroorotate dehydrogenase K17723 GO:0003674,GO:0003824,GO:0003954,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 406.0
HKD1_k127_6436521_18 Belongs to the allantoicase family K01477 GO:0003674,GO:0003824,GO:0004037,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 396.0
HKD1_k127_6436521_19 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 388.0
HKD1_k127_6436521_2 Amidohydrolase family - - - 2.643e-241 779.0
HKD1_k127_6436521_20 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 385.0
HKD1_k127_6436521_21 poly(3-hydroxybutyrate) depolymerase activity K07019 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0071704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 306.0
HKD1_k127_6436521_22 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 302.0
HKD1_k127_6436521_23 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 297.0
HKD1_k127_6436521_24 Glycosyl transferase 4-like domain K03842 GO:0000003,GO:0003006,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009856,GO:0009987,GO:0010483,GO:0012505,GO:0019538,GO:0022414,GO:0032501,GO:0032502,GO:0034645,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044706,GO:0048856,GO:0048868,GO:0051703,GO:0051704,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.142 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009505 296.0
HKD1_k127_6436521_25 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004898 285.0
HKD1_k127_6436521_26 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005557 282.0
HKD1_k127_6436521_27 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin K00365 - 1.7.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001899 270.0
HKD1_k127_6436521_28 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006007 274.0
HKD1_k127_6436521_29 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001969 262.0
HKD1_k127_6436521_3 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 8.712e-210 662.0
HKD1_k127_6436521_30 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000003956 259.0
HKD1_k127_6436521_31 FAD linked oxidases, C-terminal domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000008606 239.0
HKD1_k127_6436521_32 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000001619 217.0
HKD1_k127_6436521_33 - - - - 0.00000000000000000000000000000000000000000000000000000000007025 217.0
HKD1_k127_6436521_34 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000001162 226.0
HKD1_k127_6436521_35 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000000002214 202.0
HKD1_k127_6436521_36 Uncharacterised protein family UPF0052 - - - 0.00000000000000000000000000000000000000000000000000000005981 207.0
HKD1_k127_6436521_37 2 iron, 2 sulfur cluster binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000000000009473 186.0
HKD1_k127_6436521_38 allantoin biosynthetic process K01477,K16840 - 3.5.3.4,4.1.1.97 0.0000000000000000000000000000000000000102 151.0
HKD1_k127_6436521_39 DinB family - - - 0.00000000000000000000000000000000001128 152.0
HKD1_k127_6436521_4 PFAM amidohydrolase K01464 - 3.5.2.2 1.945e-204 646.0
HKD1_k127_6436521_40 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.000000000000000000000000000000113 128.0
HKD1_k127_6436521_41 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000003559 118.0
HKD1_k127_6436521_42 Methanol dehydrogenase K06872 - - 0.0000000000000000000003217 107.0
HKD1_k127_6436521_43 Belongs to the ompA family K03286 - - 0.0000000000000000001782 104.0
HKD1_k127_6436521_44 nucleotidyltransferase activity - - - 0.00000000000000003863 91.0
HKD1_k127_6436521_45 Stress-induced bacterial acidophilic repeat motif - - - 0.000000000000002226 80.0
HKD1_k127_6436521_5 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 614.0
HKD1_k127_6436521_6 NCS1 nucleoside transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 576.0
HKD1_k127_6436521_7 Iron-containing alcohol dehydrogenase K11173 - 1.1.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 557.0
HKD1_k127_6436521_8 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 558.0
HKD1_k127_6436521_9 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 545.0
HKD1_k127_6444186_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 477.0
HKD1_k127_6444186_1 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 394.0
HKD1_k127_6444186_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 304.0
HKD1_k127_6444186_3 Protein of unknown function (DUF1214) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002491 246.0
HKD1_k127_6444186_4 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000000000003978 197.0
HKD1_k127_6444186_5 - - - - 0.0000000000000000000000000000000000000000000006612 175.0
HKD1_k127_6469056_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1251.0
HKD1_k127_6469056_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 6.389e-278 892.0
HKD1_k127_6469056_10 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 464.0
HKD1_k127_6469056_11 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006863,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015205,GO:0015207,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015851,GO:0015853,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098655,GO:0098660,GO:0098662,GO:1902600,GO:1904823 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 454.0
HKD1_k127_6469056_12 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 443.0
HKD1_k127_6469056_13 LytB protein K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 422.0
HKD1_k127_6469056_14 D-gluconate metabolic process K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 410.0
HKD1_k127_6469056_15 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 421.0
HKD1_k127_6469056_16 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 421.0
HKD1_k127_6469056_17 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 394.0
HKD1_k127_6469056_18 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 373.0
HKD1_k127_6469056_19 PFAM Formiminotransferase K00603 - 2.1.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 346.0
HKD1_k127_6469056_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.714e-258 805.0
HKD1_k127_6469056_20 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 338.0
HKD1_k127_6469056_21 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 329.0
HKD1_k127_6469056_22 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 331.0
HKD1_k127_6469056_23 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 319.0
HKD1_k127_6469056_24 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 298.0
HKD1_k127_6469056_25 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 292.0
HKD1_k127_6469056_26 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003245 291.0
HKD1_k127_6469056_27 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001053 293.0
HKD1_k127_6469056_28 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000576 268.0
HKD1_k127_6469056_29 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000000000000000005533 247.0
HKD1_k127_6469056_3 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 4.094e-216 683.0
HKD1_k127_6469056_30 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000005101 241.0
HKD1_k127_6469056_31 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000006707 242.0
HKD1_k127_6469056_32 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000004573 216.0
HKD1_k127_6469056_33 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.0000000000000000000000000000000000000000000000000000008208 201.0
HKD1_k127_6469056_34 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000002126 183.0
HKD1_k127_6469056_35 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.0000000000000000000000000000000000000000003597 170.0
HKD1_k127_6469056_36 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000004452 165.0
HKD1_k127_6469056_37 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000001447 154.0
HKD1_k127_6469056_38 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000337 144.0
HKD1_k127_6469056_39 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000002733 152.0
HKD1_k127_6469056_4 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 4.714e-205 662.0
HKD1_k127_6469056_40 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000000000000000000000008582 148.0
HKD1_k127_6469056_41 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000792 140.0
HKD1_k127_6469056_42 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000001705 126.0
HKD1_k127_6469056_43 TIGRFAM TonB family protein K03832 - - 0.000000000000000000000000000006348 134.0
HKD1_k127_6469056_44 Putative adhesin - - - 0.0000000000000000000002147 109.0
HKD1_k127_6469056_45 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000002069 100.0
HKD1_k127_6469056_46 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000002172 94.0
HKD1_k127_6469056_47 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000004939 99.0
HKD1_k127_6469056_48 - - - - 0.0000000000000000009177 96.0
HKD1_k127_6469056_49 RNA polymerase-binding protein DksA K06204 - - 0.0000000000000001031 85.0
HKD1_k127_6469056_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 550.0
HKD1_k127_6469056_50 Belongs to the UPF0109 family K06960 - - 0.000000000000005618 82.0
HKD1_k127_6469056_51 PFAM Glucose-6-phosphate dehydrogenase subunit - - - 0.0000000002089 72.0
HKD1_k127_6469056_52 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000005405 62.0
HKD1_k127_6469056_54 Bacterial regulatory protein, Fis family - - - 0.00000003618 58.0
HKD1_k127_6469056_55 Heavy-metal resistance - - - 0.00000006845 61.0
HKD1_k127_6469056_56 Domain of unknown function (DUF4440) - - - 0.0000001711 58.0
HKD1_k127_6469056_57 RDD family - - - 0.0000002704 62.0
HKD1_k127_6469056_58 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000568 48.0
HKD1_k127_6469056_6 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 548.0
HKD1_k127_6469056_60 Heat induced stress protein YflT - - - 0.0005671 49.0
HKD1_k127_6469056_7 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 512.0
HKD1_k127_6469056_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 479.0
HKD1_k127_6469056_9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 473.0
HKD1_k127_6550217_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.303e-265 829.0
HKD1_k127_6550217_1 MacB-like periplasmic core domain - - - 1.232e-264 846.0
HKD1_k127_6550217_10 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 558.0
HKD1_k127_6550217_11 ATP-dependent helicase K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 546.0
HKD1_k127_6550217_12 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 535.0
HKD1_k127_6550217_13 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 490.0
HKD1_k127_6550217_14 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 449.0
HKD1_k127_6550217_15 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 447.0
HKD1_k127_6550217_16 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 422.0
HKD1_k127_6550217_17 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 386.0
HKD1_k127_6550217_18 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 372.0
HKD1_k127_6550217_19 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 360.0
HKD1_k127_6550217_2 MacB-like periplasmic core domain - - - 1.039e-212 687.0
HKD1_k127_6550217_20 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 364.0
HKD1_k127_6550217_21 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 342.0
HKD1_k127_6550217_22 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 366.0
HKD1_k127_6550217_23 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 329.0
HKD1_k127_6550217_24 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 341.0
HKD1_k127_6550217_25 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 329.0
HKD1_k127_6550217_26 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 327.0
HKD1_k127_6550217_27 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 313.0
HKD1_k127_6550217_28 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 301.0
HKD1_k127_6550217_29 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002319 281.0
HKD1_k127_6550217_3 radical SAM domain protein - - - 2.457e-207 659.0
HKD1_k127_6550217_30 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 265.0
HKD1_k127_6550217_31 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004647 278.0
HKD1_k127_6550217_32 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004373 270.0
HKD1_k127_6550217_33 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000181 257.0
HKD1_k127_6550217_34 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003397 259.0
HKD1_k127_6550217_35 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006552 251.0
HKD1_k127_6550217_36 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004252 252.0
HKD1_k127_6550217_37 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000003103 251.0
HKD1_k127_6550217_38 Class ii aldolase K01628,K03077,K11216 - 2.7.1.189,4.1.2.17,5.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000005932 241.0
HKD1_k127_6550217_39 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000114 244.0
HKD1_k127_6550217_4 Imidazolonepropionase and related - - - 3.148e-203 647.0
HKD1_k127_6550217_40 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000937 242.0
HKD1_k127_6550217_41 enzyme related to lactoylglutathione lyase K06996 - - 0.000000000000000000000000000000000000000000000000000000000000001993 226.0
HKD1_k127_6550217_42 SpoU rRNA Methylase family - - - 0.00000000000000000000000000000000000000000000000000000000005784 215.0
HKD1_k127_6550217_43 BlaR1 peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000008216 228.0
HKD1_k127_6550217_44 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000001081 213.0
HKD1_k127_6550217_45 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000001153 211.0
HKD1_k127_6550217_46 - - - - 0.000000000000000000000000000000000000000000000000000000001532 208.0
HKD1_k127_6550217_47 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000003716 209.0
HKD1_k127_6550217_48 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000004072 213.0
HKD1_k127_6550217_49 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000002287 188.0
HKD1_k127_6550217_5 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 629.0
HKD1_k127_6550217_50 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000008869 189.0
HKD1_k127_6550217_51 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000002175 168.0
HKD1_k127_6550217_52 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000001659 179.0
HKD1_k127_6550217_53 Penicillinase repressor - - - 0.00000000000000000000000000000000000004456 146.0
HKD1_k127_6550217_54 ethanolamine catabolic process K04027 - - 0.0000000000000000000000000000000000001312 144.0
HKD1_k127_6550217_55 YbbR-like protein - - - 0.00000000000000000000000000000004715 140.0
HKD1_k127_6550217_56 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000001449 136.0
HKD1_k127_6550217_57 DinB family - - - 0.000000000000000000000000001072 118.0
HKD1_k127_6550217_58 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000000001802 108.0
HKD1_k127_6550217_59 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000007749 97.0
HKD1_k127_6550217_6 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 595.0
HKD1_k127_6550217_60 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.000000000000000000001191 98.0
HKD1_k127_6550217_61 Tetratricopeptide repeat - - - 0.00000000000000000000131 102.0
HKD1_k127_6550217_62 positive regulation of type IV pilus biogenesis K07343 - - 0.00000000000000000007996 94.0
HKD1_k127_6550217_63 Nodulation protein S (NodS) - - - 0.0000000000000000002645 97.0
HKD1_k127_6550217_64 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000002663 101.0
HKD1_k127_6550217_65 - - - - 0.00000000000000004439 86.0
HKD1_k127_6550217_66 Polymer-forming cytoskeletal - - - 0.000000000000005817 80.0
HKD1_k127_6550217_67 peptidyl-tyrosine sulfation - - - 0.00000000000001854 84.0
HKD1_k127_6550217_68 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000001509 83.0
HKD1_k127_6550217_69 membrane - - - 0.0000002297 59.0
HKD1_k127_6550217_7 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 598.0
HKD1_k127_6550217_71 ABC-2 type transporter K01992 - - 0.0000009996 59.0
HKD1_k127_6550217_72 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000008985 56.0
HKD1_k127_6550217_73 Staphylococcal nuclease homologues K01174,K07038 - 3.1.31.1 0.0001963 51.0
HKD1_k127_6550217_74 COG2217 Cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0006981 51.0
HKD1_k127_6550217_8 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 566.0
HKD1_k127_6550217_9 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 550.0
HKD1_k127_6570061_0 Amidohydrolase family - - - 3.871e-299 952.0
HKD1_k127_6570061_1 X-Pro dipeptidyl-peptidase domain protein K06978 - - 1.21e-242 764.0
HKD1_k127_6570061_10 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 336.0
HKD1_k127_6570061_11 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 335.0
HKD1_k127_6570061_12 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000003982 202.0
HKD1_k127_6570061_13 Peptidase, M28 - - - 0.00000101 61.0
HKD1_k127_6570061_14 Cupin 2, conserved barrel domain protein - - - 0.0004736 52.0
HKD1_k127_6570061_2 Peptidase family M28 - - - 8.623e-208 660.0
HKD1_k127_6570061_3 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 594.0
HKD1_k127_6570061_4 succinyl-diaminopimelate desuccinylase activity K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 561.0
HKD1_k127_6570061_5 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 497.0
HKD1_k127_6570061_6 Isocitrate/isopropylmalate dehydrogenase K07246 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006108,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009027,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019752,GO:0036094,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046553,GO:0046872,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 481.0
HKD1_k127_6570061_7 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 389.0
HKD1_k127_6570061_8 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 355.0
HKD1_k127_6570061_9 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 350.0
HKD1_k127_6683717_0 Putative glutamine amidotransferase - - - 9.757e-195 635.0
HKD1_k127_6683717_1 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 597.0
HKD1_k127_6683717_10 Methyltransferase K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000001175 153.0
HKD1_k127_6683717_11 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.000000000000000000000000000002774 139.0
HKD1_k127_6683717_12 Sporulation and spore germination - - - 0.000000000000000002299 98.0
HKD1_k127_6683717_13 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0003061 48.0
HKD1_k127_6683717_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 430.0
HKD1_k127_6683717_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 319.0
HKD1_k127_6683717_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 300.0
HKD1_k127_6683717_5 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002615 263.0
HKD1_k127_6683717_6 MafB19-like deaminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005081 254.0
HKD1_k127_6683717_7 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000008921 197.0
HKD1_k127_6683717_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000003174 171.0
HKD1_k127_6683717_9 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000212 172.0
HKD1_k127_6789838_0 chaperone-mediated protein folding - GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 290.0
HKD1_k127_6789838_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000002215 168.0
HKD1_k127_6789838_2 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000000001339 160.0
HKD1_k127_6789838_3 Protein of unknown function (DUF1269) K03316 - - 0.00000000000000000000000000000000005186 144.0
HKD1_k127_6789838_4 unusual protein kinase K03688 - - 0.00000000000000000000000005863 112.0
HKD1_k127_6789838_5 membrane - - - 0.00000000000000000000001484 110.0
HKD1_k127_6789838_6 Protein of unknown function (DUF1269) - - - 0.00000005371 64.0
HKD1_k127_6795053_0 MacB-like periplasmic core domain - - - 2.5e-323 1009.0
HKD1_k127_6795053_1 Peptidase dimerisation domain K13049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 557.0
HKD1_k127_6795053_10 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000002048 81.0
HKD1_k127_6795053_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 561.0
HKD1_k127_6795053_3 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 550.0
HKD1_k127_6795053_4 Peptidase dimerisation domain K13049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 539.0
HKD1_k127_6795053_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 345.0
HKD1_k127_6795053_6 N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001542 213.0
HKD1_k127_6795053_7 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000148 205.0
HKD1_k127_6795053_8 DinB superfamily - - - 0.00000000000000000000000000000002353 132.0
HKD1_k127_6795053_9 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000005817 100.0
HKD1_k127_679659_0 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 5.835e-204 653.0
HKD1_k127_679659_1 Histidine kinase K02478 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 334.0
HKD1_k127_679659_2 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002683 255.0
HKD1_k127_679659_3 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000000002329 201.0
HKD1_k127_679659_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K00338 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000001905 171.0
HKD1_k127_679659_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000146 160.0
HKD1_k127_679659_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000003707 113.0
HKD1_k127_679659_7 phosphoesterases, related to the Icc protein - - - 0.00000000000000000001184 101.0
HKD1_k127_679659_8 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000001202 85.0
HKD1_k127_7052650_0 polysaccharide deactylase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 408.0
HKD1_k127_7052650_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 321.0
HKD1_k127_7052650_2 FemAB family - - - 0.000000000000000000000000000001137 128.0
HKD1_k127_7058499_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001495 272.0
HKD1_k127_7058499_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000007551 247.0
HKD1_k127_7058499_10 - K15383 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0042802,GO:0044425 - 0.00001084 52.0
HKD1_k127_7058499_2 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000000002859 208.0
HKD1_k127_7058499_3 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000003372 157.0
HKD1_k127_7058499_4 Lipocalin-like domain - - - 0.0000000000000000000000000000000004807 143.0
HKD1_k127_7058499_5 Domain of unknown function (DUF202) K00389 - - 0.0000000000000000000000000000000445 136.0
HKD1_k127_7058499_6 Protein of unknown function (DUF1353) - - - 0.000000000000000000000008044 109.0
HKD1_k127_7058499_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000001996 60.0
HKD1_k127_7058499_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000005872 61.0
HKD1_k127_7058499_9 Glutathione-dependent formaldehyde-activating - - - 0.000002014 51.0
HKD1_k127_7069155_0 Glycogen debranching enzyme - - - 0.0 1433.0
HKD1_k127_7069155_1 Dehydrogenase K00117 - 1.1.5.2 1.175e-236 752.0
HKD1_k127_7069155_10 Bile acid K03453 - - 0.000000000000000000000000000000000000000000000000000000000205 216.0
HKD1_k127_7069155_11 Cytochrome c - - - 0.00000000000000000000000000000001578 133.0
HKD1_k127_7069155_12 Tetratricopeptide repeat - - - 0.000000000000000000000000004632 121.0
HKD1_k127_7069155_13 - - - - 0.0000000000000000000000008018 111.0
HKD1_k127_7069155_14 Polymer-forming cytoskeletal - - - 0.00000000000000000000003837 103.0
HKD1_k127_7069155_15 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000001311 87.0
HKD1_k127_7069155_16 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000004525 83.0
HKD1_k127_7069155_17 oxidoreductase activity - - - 0.000000001019 72.0
HKD1_k127_7069155_18 Prolyl oligopeptidase family - - - 0.0009444 49.0
HKD1_k127_7069155_2 alpha amylase, catalytic region - - - 9.108e-224 700.0
HKD1_k127_7069155_3 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 609.0
HKD1_k127_7069155_4 Thiamine pyrophosphate enzyme, central domain K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 457.0
HKD1_k127_7069155_5 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 421.0
HKD1_k127_7069155_6 NADPH:quinone reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 371.0
HKD1_k127_7069155_7 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 364.0
HKD1_k127_7069155_8 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 297.0
HKD1_k127_7069155_9 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000651 252.0
HKD1_k127_7078406_0 intracellular protein transport - - - 2.736e-255 816.0
HKD1_k127_7078406_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 1.112e-252 807.0
HKD1_k127_7078406_10 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 341.0
HKD1_k127_7078406_11 COG1879 ABC-type sugar transport system, periplasmic component K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 322.0
HKD1_k127_7078406_12 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 338.0
HKD1_k127_7078406_13 Platelet-activating factor acetylhydrolase, plasma intracellular isoform II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001803 279.0
HKD1_k127_7078406_14 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000001078 267.0
HKD1_k127_7078406_15 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000001295 226.0
HKD1_k127_7078406_16 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001278 233.0
HKD1_k127_7078406_17 Inosine-uridine preferring nucleoside hydrolase - - - 0.00000000000000000000000000000000000000000000001451 184.0
HKD1_k127_7078406_18 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000001667 176.0
HKD1_k127_7078406_19 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000001387 169.0
HKD1_k127_7078406_2 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 1.217e-221 699.0
HKD1_k127_7078406_20 - - - - 0.00000000000000000000000000000000000001174 156.0
HKD1_k127_7078406_21 Protein of unknown function, DUF - - - 0.000000000000000000000000000000000219 138.0
HKD1_k127_7078406_22 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000002337 118.0
HKD1_k127_7078406_24 - - - - 0.0000002424 55.0
HKD1_k127_7078406_3 efflux transmembrane transporter activity - - - 9.446e-195 634.0
HKD1_k127_7078406_4 PQQ enzyme repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 591.0
HKD1_k127_7078406_5 Belongs to the ribulokinase family K00853 - 2.7.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 565.0
HKD1_k127_7078406_6 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 505.0
HKD1_k127_7078406_7 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056,K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 492.0
HKD1_k127_7078406_8 Sugar transport protein K05340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 434.0
HKD1_k127_7078406_9 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 414.0
HKD1_k127_7081116_0 COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 527.0
HKD1_k127_7081116_1 Transfers electrons from cytochrome c551 to cytochrome oxidase - - - 0.00000000000000000000000000000000000000000005063 169.0
HKD1_k127_7081116_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000008532 63.0
HKD1_k127_7081116_3 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.000000001611 61.0
HKD1_k127_7119892_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 455.0
HKD1_k127_7119892_1 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 424.0
HKD1_k127_7119892_10 SdpI/YhfL protein family - - - 0.0000000000000003578 88.0
HKD1_k127_7119892_11 lactate/malate dehydrogenase, NAD binding domain K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000008555 69.0
HKD1_k127_7119892_2 response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 396.0
HKD1_k127_7119892_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 345.0
HKD1_k127_7119892_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 351.0
HKD1_k127_7119892_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006297 244.0
HKD1_k127_7119892_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000044 224.0
HKD1_k127_7119892_7 PFAM Radical SAM domain protein K06871 - - 0.00000000000000000000000000000000000000000000000000004043 206.0
HKD1_k127_7119892_8 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000119 123.0
HKD1_k127_7119892_9 - - - - 0.00000000000000000000000003367 109.0
HKD1_k127_7139466_0 cellulose binding - - - 1.813e-247 799.0
HKD1_k127_7139466_1 Uncharacterized protein conserved in bacteria (DUF2330) K00347,K21163 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 554.0
HKD1_k127_7139466_10 domain protein - - - 0.00009303 49.0
HKD1_k127_7139466_11 Protein of unknown function (DUF2934) - - - 0.0001162 50.0
HKD1_k127_7139466_12 protein related to plant photosystem II stability assembly factor - - - 0.0007971 51.0
HKD1_k127_7139466_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 452.0
HKD1_k127_7139466_3 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 294.0
HKD1_k127_7139466_4 Uncharacterized protein conserved in bacteria (DUF2330) K00347,K21163 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 288.0
HKD1_k127_7139466_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003293 274.0
HKD1_k127_7139466_6 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000001649 163.0
HKD1_k127_7139466_7 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000004395 111.0
HKD1_k127_7139466_8 helix_turn_helix, arabinose operon control protein - - - 0.00000000000001106 76.0
HKD1_k127_7139466_9 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000005579 69.0
HKD1_k127_7180794_0 Carboxypeptidase regulatory-like domain - - - 1.344e-203 664.0
HKD1_k127_7180794_1 Belongs to the TPP enzyme family K01576,K01652 - 2.2.1.6,4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 559.0
HKD1_k127_7180794_10 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000001943 214.0
HKD1_k127_7180794_11 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000006127 206.0
HKD1_k127_7180794_12 Pyruvate phosphate dikinase - - - 0.0000000000000000000000000000000000000000000000001134 184.0
HKD1_k127_7180794_13 - - - - 0.00000000000000000000000000000000000000002048 168.0
HKD1_k127_7180794_14 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.0000000000000000000000000000000000000001167 160.0
HKD1_k127_7180794_15 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000257 135.0
HKD1_k127_7180794_16 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.000000000000000000000000000001531 128.0
HKD1_k127_7180794_17 transcriptional regulator, ArsR family protein K03892 - - 0.0000000000000000000001179 105.0
HKD1_k127_7180794_18 - - - - 0.000000000000000000001377 106.0
HKD1_k127_7180794_19 pyridoxamine 5-phosphate - - - 0.00000000000000000004786 96.0
HKD1_k127_7180794_2 Domain of unknown function (DUF1929) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 536.0
HKD1_k127_7180794_20 - K01865 - 5.4.4.1 0.0000000000000000002623 96.0
HKD1_k127_7180794_21 Cytochrome c K17760 - 1.1.9.1 0.000000000006163 71.0
HKD1_k127_7180794_22 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000006545 63.0
HKD1_k127_7180794_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 430.0
HKD1_k127_7180794_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 366.0
HKD1_k127_7180794_5 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 317.0
HKD1_k127_7180794_6 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 289.0
HKD1_k127_7180794_7 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003493 292.0
HKD1_k127_7180794_8 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005666 284.0
HKD1_k127_7180794_9 Flavodoxin-like fold K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000138 273.0
HKD1_k127_7200273_0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1276.0
HKD1_k127_7200273_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 6.776e-285 895.0
HKD1_k127_7200273_2 PFAM Rhomboid family protein - - - 0.00000000000000000000008948 102.0
HKD1_k127_7216780_0 DEAD DEAH box K03724 - - 0.0 1870.0
HKD1_k127_7216780_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1238.0
HKD1_k127_7216780_10 DNA topological change - - - 5.33e-244 778.0
HKD1_k127_7216780_100 Esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000001263 210.0
HKD1_k127_7216780_101 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000002257 190.0
HKD1_k127_7216780_102 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K02528,K16924 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.1.1.182,2.7.1.148 0.000000000000000000000000000000000000000000000000002732 193.0
HKD1_k127_7216780_103 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000003815 184.0
HKD1_k127_7216780_104 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000004452 186.0
HKD1_k127_7216780_105 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000469 199.0
HKD1_k127_7216780_106 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000001799 187.0
HKD1_k127_7216780_107 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000008294 192.0
HKD1_k127_7216780_108 - - - - 0.000000000000000000000000000000000000000000000003421 175.0
HKD1_k127_7216780_109 AMP binding - - - 0.00000000000000000000000000000000000000000001252 174.0
HKD1_k127_7216780_11 Phosphoribosyl transferase domain K07100 - - 2.09e-243 771.0
HKD1_k127_7216780_110 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000007328 168.0
HKD1_k127_7216780_111 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000876 171.0
HKD1_k127_7216780_112 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000000000000000001302 176.0
HKD1_k127_7216780_113 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000008363 159.0
HKD1_k127_7216780_114 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000001815 156.0
HKD1_k127_7216780_115 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000002234 155.0
HKD1_k127_7216780_116 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.00000000000000000000000000000000000001094 148.0
HKD1_k127_7216780_117 DinB superfamily - - - 0.00000000000000000000000000000000000001715 151.0
HKD1_k127_7216780_118 response to heat - - - 0.00000000000000000000000000000000000006828 153.0
HKD1_k127_7216780_119 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000542 146.0
HKD1_k127_7216780_12 Serine carboxypeptidase - - - 5.983e-238 744.0
HKD1_k127_7216780_120 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000001317 138.0
HKD1_k127_7216780_121 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000002672 143.0
HKD1_k127_7216780_122 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000003862 135.0
HKD1_k127_7216780_123 DinB superfamily - - - 0.000000000000000000000000000000004378 136.0
HKD1_k127_7216780_124 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000008149 140.0
HKD1_k127_7216780_125 Belongs to the UPF0234 family K09767 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000002637 131.0
HKD1_k127_7216780_126 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000006488 143.0
HKD1_k127_7216780_127 - - - - 0.0000000000000000000000000000001323 129.0
HKD1_k127_7216780_128 - - - - 0.0000000000000000000000000000008641 132.0
HKD1_k127_7216780_129 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000001273 129.0
HKD1_k127_7216780_13 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.196e-231 732.0
HKD1_k127_7216780_130 belongs to the carbohydrate kinase PfkB family - - - 0.00000000000000000000000000000174 132.0
HKD1_k127_7216780_131 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000005762 134.0
HKD1_k127_7216780_132 - - - - 0.00000000000000000000000000001201 124.0
HKD1_k127_7216780_133 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000002217 119.0
HKD1_k127_7216780_134 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000005751 115.0
HKD1_k127_7216780_135 Putative zinc-finger - - - 0.00000000000000000000000000228 119.0
HKD1_k127_7216780_136 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000004632 121.0
HKD1_k127_7216780_137 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000006402 109.0
HKD1_k127_7216780_138 YCII-related domain - - - 0.0000000000000000000002293 103.0
HKD1_k127_7216780_139 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000001469 97.0
HKD1_k127_7216780_14 Sugar (and other) transporter K03761 - - 2.698e-213 672.0
HKD1_k127_7216780_140 PFAM phosphoesterase, PA-phosphatase related - - - 0.00000000000000000002667 100.0
HKD1_k127_7216780_141 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000002718 99.0
HKD1_k127_7216780_142 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000002 95.0
HKD1_k127_7216780_143 electron transfer activity K02660 - - 0.00000000000000003682 86.0
HKD1_k127_7216780_144 Trm112p-like protein K00912,K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 0.00000000000000003821 83.0
HKD1_k127_7216780_146 DinB family - - - 0.00000000000000007664 89.0
HKD1_k127_7216780_147 - - - - 0.00000000000000007764 87.0
HKD1_k127_7216780_149 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.000000000002457 78.0
HKD1_k127_7216780_15 Carboxypeptidase regulatory-like domain - - - 1.919e-207 674.0
HKD1_k127_7216780_150 - - - - 0.000000000003161 77.0
HKD1_k127_7216780_152 - - - - 0.00000000006756 70.0
HKD1_k127_7216780_153 - - - - 0.0000000009077 66.0
HKD1_k127_7216780_154 Putative prokaryotic signal transducing protein - - - 0.000000004782 63.0
HKD1_k127_7216780_156 Protein of unknown function (DUF3891) - - - 0.0000000513 64.0
HKD1_k127_7216780_157 non supervised orthologous group - - - 0.0000007294 62.0
HKD1_k127_7216780_158 Lysylphosphatidylglycerol synthase TM region - - - 0.000005636 59.0
HKD1_k127_7216780_159 Transcriptional regulator of aromatic amino acids metabolism K03721 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00001301 54.0
HKD1_k127_7216780_16 Endoribonuclease L-PSP - - - 4.885e-206 659.0
HKD1_k127_7216780_161 Right handed beta helix region - - - 0.0002965 53.0
HKD1_k127_7216780_17 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 4.304e-204 654.0
HKD1_k127_7216780_18 PFAM LmbE family protein - - - 3.133e-202 660.0
HKD1_k127_7216780_19 PQQ-like domain K00114 - 1.1.2.8 1.283e-201 644.0
HKD1_k127_7216780_2 Cytochrome c - - - 0.0 1126.0
HKD1_k127_7216780_20 long-chain fatty acid transporting porin activity - - - 1.128e-196 623.0
HKD1_k127_7216780_21 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 592.0
HKD1_k127_7216780_22 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 582.0
HKD1_k127_7216780_23 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 587.0
HKD1_k127_7216780_24 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 582.0
HKD1_k127_7216780_25 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007785 577.0
HKD1_k127_7216780_26 PFAM Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 564.0
HKD1_k127_7216780_27 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 573.0
HKD1_k127_7216780_28 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 557.0
HKD1_k127_7216780_29 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 514.0
HKD1_k127_7216780_3 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 4.367e-315 980.0
HKD1_k127_7216780_30 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 522.0
HKD1_k127_7216780_31 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 524.0
HKD1_k127_7216780_32 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 530.0
HKD1_k127_7216780_33 PFAM sodium hydrogen exchanger K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 512.0
HKD1_k127_7216780_34 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000911 504.0
HKD1_k127_7216780_35 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 497.0
HKD1_k127_7216780_36 Ankyrin repeats (many copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 507.0
HKD1_k127_7216780_37 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 495.0
HKD1_k127_7216780_38 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 490.0
HKD1_k127_7216780_39 Glutamate carboxypeptidase II K01301 - 3.4.17.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 496.0
HKD1_k127_7216780_4 PFAM ABC transporter - - - 2.446e-284 880.0
HKD1_k127_7216780_40 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 472.0
HKD1_k127_7216780_41 Ankyrin repeats (many copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 483.0
HKD1_k127_7216780_42 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 471.0
HKD1_k127_7216780_43 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 490.0
HKD1_k127_7216780_44 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 490.0
HKD1_k127_7216780_45 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008685 469.0
HKD1_k127_7216780_46 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 459.0
HKD1_k127_7216780_47 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 468.0
HKD1_k127_7216780_48 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 459.0
HKD1_k127_7216780_49 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 440.0
HKD1_k127_7216780_5 TonB-dependent Receptor Plug Domain - - - 2.664e-274 878.0
HKD1_k127_7216780_50 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 424.0
HKD1_k127_7216780_51 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 406.0
HKD1_k127_7216780_52 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 397.0
HKD1_k127_7216780_53 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 415.0
HKD1_k127_7216780_54 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 394.0
HKD1_k127_7216780_55 Amidohydrolase K10220 - 4.2.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 401.0
HKD1_k127_7216780_56 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 394.0
HKD1_k127_7216780_57 Sugar (and other) transporter K08195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 408.0
HKD1_k127_7216780_58 glycerophosphoryl diester phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 383.0
HKD1_k127_7216780_59 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 385.0
HKD1_k127_7216780_6 Protein of unknown function (DUF1595) - - - 9.543e-263 833.0
HKD1_k127_7216780_60 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 372.0
HKD1_k127_7216780_61 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 380.0
HKD1_k127_7216780_62 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 368.0
HKD1_k127_7216780_63 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 364.0
HKD1_k127_7216780_64 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 355.0
HKD1_k127_7216780_65 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 347.0
HKD1_k127_7216780_66 Family 4 glycosyl hydrolase K01222 - 3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 353.0
HKD1_k127_7216780_67 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 329.0
HKD1_k127_7216780_68 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 321.0
HKD1_k127_7216780_69 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 321.0
HKD1_k127_7216780_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.38e-258 815.0
HKD1_k127_7216780_70 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 307.0
HKD1_k127_7216780_71 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 302.0
HKD1_k127_7216780_72 Sensor histidine kinase, HAMP domain-containing K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 306.0
HKD1_k127_7216780_73 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 302.0
HKD1_k127_7216780_74 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 312.0
HKD1_k127_7216780_75 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001106 280.0
HKD1_k127_7216780_76 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002902 273.0
HKD1_k127_7216780_77 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002049 269.0
HKD1_k127_7216780_78 phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007304 264.0
HKD1_k127_7216780_79 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000006492 245.0
HKD1_k127_7216780_8 succinyl-diaminopimelate desuccinylase activity - - - 1.391e-250 784.0
HKD1_k127_7216780_80 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006919 255.0
HKD1_k127_7216780_81 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000002742 253.0
HKD1_k127_7216780_82 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000001562 255.0
HKD1_k127_7216780_83 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003221 247.0
HKD1_k127_7216780_84 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005313 246.0
HKD1_k127_7216780_85 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000005593 259.0
HKD1_k127_7216780_86 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000004897 255.0
HKD1_k127_7216780_87 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.0000000000000000000000000000000000000000000000000000000000000000003168 239.0
HKD1_k127_7216780_88 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009756 252.0
HKD1_k127_7216780_89 COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains K12266 - - 0.000000000000000000000000000000000000000000000000000000000000000007105 240.0
HKD1_k127_7216780_9 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 1.287e-246 778.0
HKD1_k127_7216780_90 O-acyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000005511 233.0
HKD1_k127_7216780_91 - - - - 0.00000000000000000000000000000000000000000000000000000000000007517 220.0
HKD1_k127_7216780_92 - - - - 0.0000000000000000000000000000000000000000000000000000000000001169 241.0
HKD1_k127_7216780_93 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000001319 223.0
HKD1_k127_7216780_94 Transcriptional regulator K07669 - - 0.00000000000000000000000000000000000000000000000000000000000907 215.0
HKD1_k127_7216780_95 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000006077 201.0
HKD1_k127_7216780_96 O-Antigen ligase K18814 - - 0.0000000000000000000000000000000000000000000000000000002353 209.0
HKD1_k127_7216780_97 conserved protein - - - 0.00000000000000000000000000000000000000000000000000002002 199.0
HKD1_k127_7216780_98 Glycosyl transferase, family 9 K02843,K02849 - - 0.0000000000000000000000000000000000000000000000000002302 198.0
HKD1_k127_7216780_99 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000248 194.0
HKD1_k127_7218738_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 416.0
HKD1_k127_7218738_1 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000005873 187.0
HKD1_k127_7218738_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001036 193.0
HKD1_k127_7218738_3 cellulose binding - - - 0.0000000000000008044 83.0
HKD1_k127_7237458_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 2.961e-309 968.0
HKD1_k127_7237458_1 serine dehydratase beta chain K01752 - 4.3.1.17 8.544e-253 791.0
HKD1_k127_7237458_10 Short chain fatty K02106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 417.0
HKD1_k127_7237458_11 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 427.0
HKD1_k127_7237458_12 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 386.0
HKD1_k127_7237458_13 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 376.0
HKD1_k127_7237458_14 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 376.0
HKD1_k127_7237458_15 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 368.0
HKD1_k127_7237458_16 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 364.0
HKD1_k127_7237458_17 PFAM Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 349.0
HKD1_k127_7237458_18 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 349.0
HKD1_k127_7237458_19 NADH ubiquinone oxidoreductase subunit 5 (chain L) K05577 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 342.0
HKD1_k127_7237458_2 Belongs to the UPF0753 family K09822 - - 2.231e-231 749.0
HKD1_k127_7237458_20 electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 337.0
HKD1_k127_7237458_21 virulence factor implicated in the pathogenesis of mycobacterium tuberculosis at the level of intracellular survival, by the alteration of cell signaling events or by direct cytotoxicity catalytic activity a phosphatidylcholine H(2)O 1,2- diacylglycerol choline phosphate K01114 GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006629,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009405,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0034480,GO:0035821,GO:0042578,GO:0044003,GO:0044238,GO:0044403,GO:0044419,GO:0044464,GO:0051701,GO:0051704,GO:0051817,GO:0052008,GO:0052043,GO:0052111,GO:0052185,GO:0052188,GO:0052368,GO:0071704,GO:0071944,GO:1901575 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 308.0
HKD1_k127_7237458_22 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001256 275.0
HKD1_k127_7237458_23 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001947 263.0
HKD1_k127_7237458_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000007913 228.0
HKD1_k127_7237458_25 NADH ubiquinone oxidoreductase subunit 4 (Chain M) K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000001868 234.0
HKD1_k127_7237458_26 PFAM Dynamin family protein - - - 0.00000000000000000000000000000000000000000000000000003034 208.0
HKD1_k127_7237458_27 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000968 190.0
HKD1_k127_7237458_28 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000001903 186.0
HKD1_k127_7237458_29 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000331 171.0
HKD1_k127_7237458_3 Tfp pilus assembly protein FimV - - - 8.434e-214 673.0
HKD1_k127_7237458_30 AI-2E family transporter - - - 0.000000000000000000000000000000000000000002261 158.0
HKD1_k127_7237458_31 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000008664 151.0
HKD1_k127_7237458_32 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000005081 143.0
HKD1_k127_7237458_33 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.000000000000000000000000000000000004686 150.0
HKD1_k127_7237458_34 - - - - 0.00000000000000000000000000000000003363 143.0
HKD1_k127_7237458_35 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000988 137.0
HKD1_k127_7237458_36 Helix-turn-helix domain - - - 0.00000000000000000000000000000000112 137.0
HKD1_k127_7237458_37 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00000000000000000000000000000003556 133.0
HKD1_k127_7237458_38 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000004192 127.0
HKD1_k127_7237458_39 MerR, DNA binding K19591 - - 0.0000000000000000000000000000004466 126.0
HKD1_k127_7237458_4 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 616.0
HKD1_k127_7237458_40 ArsR family transcriptional regulator - - - 0.0000000000000000000000000000012 125.0
HKD1_k127_7237458_41 Protein tyrosine kinase K08884 - 2.7.11.1 0.000000000000000000000000004589 123.0
HKD1_k127_7237458_42 PFAM DsrE DsrF-like family K09004 - - 0.00000000000000000000000003011 114.0
HKD1_k127_7237458_43 Amidase - - - 0.00000000000000000000000003202 111.0
HKD1_k127_7237458_44 - - - - 0.000000000000000000000008531 119.0
HKD1_k127_7237458_45 Cold shock protein domain - - - 0.000000000000000000003311 95.0
HKD1_k127_7237458_46 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000001724 83.0
HKD1_k127_7237458_47 pfam yhs - - - 0.0000000000000005485 78.0
HKD1_k127_7237458_48 - - - - 0.00000000000004756 81.0
HKD1_k127_7237458_49 glyoxalase III activity - - - 0.000000000005895 78.0
HKD1_k127_7237458_5 Reductase C-terminal K05297 - 1.18.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 607.0
HKD1_k127_7237458_50 - - - - 0.000000005078 66.0
HKD1_k127_7237458_51 Domain of unknown function (DUF4070) - - - 0.00006465 48.0
HKD1_k127_7237458_6 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 594.0
HKD1_k127_7237458_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 469.0
HKD1_k127_7237458_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 449.0
HKD1_k127_7237458_9 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 448.0
HKD1_k127_7293599_0 Oxidoreductase - - - 4.013e-275 857.0
HKD1_k127_7293599_1 Dehydrogenase K00117 - 1.1.5.2 3.441e-271 852.0
HKD1_k127_7293599_10 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 339.0
HKD1_k127_7293599_11 PFAM Cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 306.0
HKD1_k127_7293599_12 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 307.0
HKD1_k127_7293599_14 Gluconate 2-dehydrogenase subunit 3 - - - 0.00000000000000000000000000000000000000000000000003499 186.0
HKD1_k127_7293599_15 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000001456 97.0
HKD1_k127_7293599_16 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000123 52.0
HKD1_k127_7293599_17 Pfam SNARE associated Golgi protein K03975 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00006735 46.0
HKD1_k127_7293599_2 PQQ enzyme repeat K00114 - 1.1.2.8 6.672e-252 797.0
HKD1_k127_7293599_3 Nucleoside H+ symporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 502.0
HKD1_k127_7293599_4 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 486.0
HKD1_k127_7293599_5 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 477.0
HKD1_k127_7293599_6 AP endonuclease family 2 C terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 447.0
HKD1_k127_7293599_7 nitric oxide dioxygenase activity K00523,K15983 - 1.14.13.142,1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 406.0
HKD1_k127_7293599_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 423.0
HKD1_k127_7293599_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 406.0
HKD1_k127_7401374_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 8.891e-289 914.0
HKD1_k127_7401374_1 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 588.0
HKD1_k127_7401374_10 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001712 298.0
HKD1_k127_7401374_11 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000000000000000000000000000005418 255.0
HKD1_k127_7401374_12 Flagellar biogenesis master sigma-54-dependent transcriptional response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000008808 243.0
HKD1_k127_7401374_13 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000102 233.0
HKD1_k127_7401374_14 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000024 229.0
HKD1_k127_7401374_15 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000306 209.0
HKD1_k127_7401374_16 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000005368 192.0
HKD1_k127_7401374_17 chlorophyll binding K03286 - - 0.000000000000000000000000000000004024 137.0
HKD1_k127_7401374_18 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000002005 127.0
HKD1_k127_7401374_19 aminopeptidase activity - - - 0.000000000000000000000000000003058 137.0
HKD1_k127_7401374_2 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 541.0
HKD1_k127_7401374_20 FecR protein - - - 0.000000000000000000000000004866 117.0
HKD1_k127_7401374_21 - - - - 0.00000000000000000000000002527 120.0
HKD1_k127_7401374_22 phosphorelay signal transduction system - - - 0.00000000000000000000000005319 118.0
HKD1_k127_7401374_23 aminopeptidase activity - - - 0.000000000000000000000001107 119.0
HKD1_k127_7401374_24 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000022 94.0
HKD1_k127_7401374_25 chromosome segregation K03497 - - 0.0000000000000000002538 100.0
HKD1_k127_7401374_26 TamB, inner membrane protein subunit of TAM complex - - - 0.0000000000001551 86.0
HKD1_k127_7401374_27 phosphorelay sensor kinase activity K01768,K07720 - 4.6.1.1 0.0000000000001621 82.0
HKD1_k127_7401374_28 - - - - 0.000000000001255 74.0
HKD1_k127_7401374_29 - - - - 0.00000001436 58.0
HKD1_k127_7401374_3 Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 511.0
HKD1_k127_7401374_30 TonB-dependent Receptor Plug Domain - - - 0.0000001027 58.0
HKD1_k127_7401374_31 PFAM PEGA domain - - - 0.0000008087 61.0
HKD1_k127_7401374_32 response regulator, receiver - - - 0.00005108 51.0
HKD1_k127_7401374_33 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0001145 54.0
HKD1_k127_7401374_34 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.0005507 48.0
HKD1_k127_7401374_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 505.0
HKD1_k127_7401374_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 448.0
HKD1_k127_7401374_6 Chase2 domain K01768,K07814 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 454.0
HKD1_k127_7401374_7 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 427.0
HKD1_k127_7401374_8 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 434.0
HKD1_k127_7401374_9 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007822 421.0
HKD1_k127_7459726_0 - - - - 0.00000000000000000000000000000000000000000000000573 183.0
HKD1_k127_7459726_1 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000006743 100.0
HKD1_k127_7459726_2 Cytochrome c - - - 0.000000000002156 72.0
HKD1_k127_7515719_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1301.0
HKD1_k127_7515719_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1239.0
HKD1_k127_7515719_10 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 480.0
HKD1_k127_7515719_11 Amino acid permease K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 467.0
HKD1_k127_7515719_12 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 468.0
HKD1_k127_7515719_13 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 469.0
HKD1_k127_7515719_14 Voltage-dependent anion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 428.0
HKD1_k127_7515719_15 mechanosensitive ion channel K03442,K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 366.0
HKD1_k127_7515719_16 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009776 350.0
HKD1_k127_7515719_17 quinone binding K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 326.0
HKD1_k127_7515719_18 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 302.0
HKD1_k127_7515719_19 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000000005205 236.0
HKD1_k127_7515719_2 Involved in the tonB-independent uptake of proteins - - - 1.753e-247 782.0
HKD1_k127_7515719_20 Cyclic nucleotide-monophosphate binding domain K21564 - - 0.000000000000000000000000000000000000000000000000000000000000000002266 235.0
HKD1_k127_7515719_21 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000009914 224.0
HKD1_k127_7515719_22 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.0000000000000000000000000000000000000000000000000000000000000009957 222.0
HKD1_k127_7515719_23 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000008192 203.0
HKD1_k127_7515719_24 membrane - - - 0.00000000000000000000000000000000000000002601 156.0
HKD1_k127_7515719_25 Hydrolase - - - 0.00000000000000000000000000000000000000003414 163.0
HKD1_k127_7515719_26 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000005371 156.0
HKD1_k127_7515719_27 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000135 159.0
HKD1_k127_7515719_28 protein deglycation K05520 - 3.5.1.124 0.000000000000000000000000000000000000002458 149.0
HKD1_k127_7515719_29 - - - - 0.0000000000000000000000000000000000001085 150.0
HKD1_k127_7515719_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.23e-215 690.0
HKD1_k127_7515719_30 Cupin domain - - - 0.0000000000000000000000000000000000002358 143.0
HKD1_k127_7515719_32 - - - - 0.00000000000000000000000000000007919 133.0
HKD1_k127_7515719_33 - - - - 0.000000000000000000000000000001826 120.0
HKD1_k127_7515719_34 Pfam:DUF59 - - - 0.0000000000000000000000000007666 115.0
HKD1_k127_7515719_35 Cupin 2, conserved barrel domain protein K16953,K19547 - 4.4.1.3,5.3.3.19 0.000000000000000000000001022 111.0
HKD1_k127_7515719_36 - - - - 0.0000000000000000007464 88.0
HKD1_k127_7515719_37 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.00000000000000001865 85.0
HKD1_k127_7515719_38 - - - - 0.0000000000000006994 80.0
HKD1_k127_7515719_39 - - - - 0.0000000000003433 69.0
HKD1_k127_7515719_4 Amidohydrolase family K06015 - 3.5.1.81 1.152e-214 680.0
HKD1_k127_7515719_40 LysR substrate binding domain K03717 - - 0.000000006614 59.0
HKD1_k127_7515719_41 PFAM PEGA domain - - - 0.00000002787 65.0
HKD1_k127_7515719_42 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.00000004816 58.0
HKD1_k127_7515719_43 - - - - 0.0000005922 63.0
HKD1_k127_7515719_44 ubiE/COQ5 methyltransferase family - - - 0.00004814 56.0
HKD1_k127_7515719_45 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00005308 54.0
HKD1_k127_7515719_46 Plasmid stabilization system K19092 - - 0.0005888 46.0
HKD1_k127_7515719_5 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 2.605e-210 673.0
HKD1_k127_7515719_6 Cytochrome c - - - 1.071e-207 653.0
HKD1_k127_7515719_7 IgA Peptidase M64 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 615.0
HKD1_k127_7515719_8 nitrite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 517.0
HKD1_k127_7515719_9 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 511.0
HKD1_k127_7535538_0 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 604.0
HKD1_k127_7535538_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 518.0
HKD1_k127_7535538_2 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 386.0
HKD1_k127_7535538_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000002716 250.0
HKD1_k127_7535538_4 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000006682 209.0
HKD1_k127_7535538_5 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000001821 174.0
HKD1_k127_7694406_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1e-323 1007.0
HKD1_k127_7694406_1 repeat protein - - - 2.307e-229 736.0
HKD1_k127_7694406_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001567 250.0
HKD1_k127_7694406_11 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000289 238.0
HKD1_k127_7694406_12 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000903 221.0
HKD1_k127_7694406_13 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000000000000000000000000004625 186.0
HKD1_k127_7694406_14 Polyketide cyclase / dehydrase and lipid transport K09386 - - 0.000000000000000000000000000000005086 134.0
HKD1_k127_7694406_15 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000004501 115.0
HKD1_k127_7694406_16 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000007267 89.0
HKD1_k127_7694406_17 serine-type peptidase activity - - - 0.00000000000001382 75.0
HKD1_k127_7694406_18 Belongs to the tannase family K09252 - 3.1.1.73 0.000007225 49.0
HKD1_k127_7694406_19 - - - - 0.0001516 48.0
HKD1_k127_7694406_2 repeat protein - - - 2.275e-223 708.0
HKD1_k127_7694406_20 - - - - 0.0003375 53.0
HKD1_k127_7694406_3 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 385.0
HKD1_k127_7694406_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 347.0
HKD1_k127_7694406_5 SMART von Willebrand factor, type A K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 338.0
HKD1_k127_7694406_6 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 340.0
HKD1_k127_7694406_7 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 329.0
HKD1_k127_7694406_8 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002767 273.0
HKD1_k127_7694406_9 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000117 269.0
HKD1_k127_7706741_0 metallocarboxypeptidase activity K14054 - - 0.0 1386.0
HKD1_k127_7706741_1 Peptidase M14, carboxypeptidase A - - - 0.0 1385.0
HKD1_k127_7706741_10 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000001474 232.0
HKD1_k127_7706741_11 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000003821 220.0
HKD1_k127_7706741_12 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000007506 207.0
HKD1_k127_7706741_13 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000003735 184.0
HKD1_k127_7706741_14 BMC - - - 0.000000000000000000000000000000002564 131.0
HKD1_k127_7706741_15 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000001546 101.0
HKD1_k127_7706741_16 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.00000000000000000872 90.0
HKD1_k127_7706741_17 BON domain - - - 0.00000000000000003896 93.0
HKD1_k127_7706741_18 helix_turn_helix, mercury resistance - - - 0.0000000000000011 83.0
HKD1_k127_7706741_2 - - - - 1.637e-214 685.0
HKD1_k127_7706741_20 Psort location Periplasmic, score K05349 - 3.2.1.21 0.000000001362 72.0
HKD1_k127_7706741_21 Protein conserved in bacteria - - - 0.00000003577 62.0
HKD1_k127_7706741_3 metal-dependent hydrolase with the TIM-barrel fold - - - 1.788e-198 633.0
HKD1_k127_7706741_4 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009754 472.0
HKD1_k127_7706741_5 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 424.0
HKD1_k127_7706741_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 383.0
HKD1_k127_7706741_7 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 295.0
HKD1_k127_7706741_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005661 283.0
HKD1_k127_7706741_9 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000001213 230.0
HKD1_k127_7722226_0 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000007607 167.0
HKD1_k127_7722226_1 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000001139 176.0
HKD1_k127_7722226_2 - - - - 0.00000000000002922 79.0
HKD1_k127_7735400_0 Sortilin, neurotensin receptor 3, - - - 0.0 1099.0
HKD1_k127_7735400_1 MacB-like periplasmic core domain - - - 0.0 1032.0
HKD1_k127_7735400_10 PFAM peptidase M1, membrane alanine aminopeptidase - - - 4.231e-208 661.0
HKD1_k127_7735400_11 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 7.553e-203 658.0
HKD1_k127_7735400_12 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 620.0
HKD1_k127_7735400_13 PQQ-like domain K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 596.0
HKD1_k127_7735400_14 His Kinase A (phosphoacceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 604.0
HKD1_k127_7735400_15 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 574.0
HKD1_k127_7735400_16 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 554.0
HKD1_k127_7735400_17 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 549.0
HKD1_k127_7735400_18 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 548.0
HKD1_k127_7735400_19 PFAM Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000775 520.0
HKD1_k127_7735400_2 Belongs to the glycosyl hydrolase 31 family K01187,K01811 - 3.2.1.177,3.2.1.20 4.219e-298 936.0
HKD1_k127_7735400_20 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 486.0
HKD1_k127_7735400_21 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 478.0
HKD1_k127_7735400_22 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 465.0
HKD1_k127_7735400_23 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 460.0
HKD1_k127_7735400_24 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 469.0
HKD1_k127_7735400_25 Peptidase m28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 461.0
HKD1_k127_7735400_26 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04127,K11325,K21174 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 451.0
HKD1_k127_7735400_27 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 473.0
HKD1_k127_7735400_28 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009351 447.0
HKD1_k127_7735400_29 polysaccharide catabolic process K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 429.0
HKD1_k127_7735400_3 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 8.798e-260 826.0
HKD1_k127_7735400_30 succinyl-diaminopimelate desuccinylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 429.0
HKD1_k127_7735400_31 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 404.0
HKD1_k127_7735400_32 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 389.0
HKD1_k127_7735400_33 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 363.0
HKD1_k127_7735400_34 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 356.0
HKD1_k127_7735400_35 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 344.0
HKD1_k127_7735400_36 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 343.0
HKD1_k127_7735400_37 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 338.0
HKD1_k127_7735400_38 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 316.0
HKD1_k127_7735400_39 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 307.0
HKD1_k127_7735400_4 Peptidase family M49 K01277 - 3.4.14.4 5.045e-258 811.0
HKD1_k127_7735400_40 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 307.0
HKD1_k127_7735400_41 D-amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 298.0
HKD1_k127_7735400_42 Aminotransferase class-V K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 297.0
HKD1_k127_7735400_43 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003556 265.0
HKD1_k127_7735400_44 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001828 269.0
HKD1_k127_7735400_45 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000002762 250.0
HKD1_k127_7735400_46 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002758 246.0
HKD1_k127_7735400_47 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004014 234.0
HKD1_k127_7735400_48 Helix-turn-helix type 11 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000005587 222.0
HKD1_k127_7735400_49 PFAM glycoside hydrolase, clan GH-D K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000007243 238.0
HKD1_k127_7735400_5 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 3.837e-248 770.0
HKD1_k127_7735400_50 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000001288 213.0
HKD1_k127_7735400_51 Nicotinamide mononucleotide transporter K03811 - - 0.000000000000000000000000000000000000000000000000000000000005536 214.0
HKD1_k127_7735400_52 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000221 205.0
HKD1_k127_7735400_53 DinB family - - - 0.00000000000000000000000000000000000000000000000001382 184.0
HKD1_k127_7735400_54 Disulphide isomerase - - - 0.00000000000000000000000000000000000000000000002847 174.0
HKD1_k127_7735400_55 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000006194 178.0
HKD1_k127_7735400_56 Dehydrogenase K00114,K17760,K20936,K21676,K22473 - 1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2 0.000000000000000000000000000000000000000000003105 175.0
HKD1_k127_7735400_57 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000832 164.0
HKD1_k127_7735400_58 Type II secretory pathway, component ExeA K02450 - - 0.0000000000000000000000000000000000000000001969 176.0
HKD1_k127_7735400_59 - - - - 0.0000000000000000000000000000000000000000002898 166.0
HKD1_k127_7735400_6 TonB-dependent receptor - - - 4.015e-236 769.0
HKD1_k127_7735400_60 Cytochrome c - - - 0.000000000000000000000000000000000000000001076 165.0
HKD1_k127_7735400_61 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000000000003101 157.0
HKD1_k127_7735400_62 glyoxalase III activity - - - 0.000000000000000000000000000000000000006607 154.0
HKD1_k127_7735400_63 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000003368 154.0
HKD1_k127_7735400_64 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000006033 138.0
HKD1_k127_7735400_65 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000001975 140.0
HKD1_k127_7735400_67 Glycosyltransferase family 87 - - - 0.00000000000000000000000000001314 134.0
HKD1_k127_7735400_68 - - - - 0.000000000000000000000000000032 132.0
HKD1_k127_7735400_69 Belongs to the arginase family K01476 - 3.5.3.1 0.00000000000000000000000000004242 128.0
HKD1_k127_7735400_7 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 3.403e-223 717.0
HKD1_k127_7735400_70 cell redox homeostasis K02199 - - 0.0000000000000000000000000001198 127.0
HKD1_k127_7735400_71 YXWGXW repeat (2 copies) - - - 0.0000000000000000000000000002605 120.0
HKD1_k127_7735400_72 membrane K08972 - - 0.000000000000000000000000004045 114.0
HKD1_k127_7735400_73 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000001355 117.0
HKD1_k127_7735400_74 amine dehydrogenase activity - - - 0.0000000000000000000000004477 118.0
HKD1_k127_7735400_75 translation initiation factor activity K06996 - - 0.0000000000000000000000005947 109.0
HKD1_k127_7735400_76 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000001255 113.0
HKD1_k127_7735400_77 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000003771 105.0
HKD1_k127_7735400_78 - - - - 0.00000000000000000006294 94.0
HKD1_k127_7735400_79 ATPase kinase involved in NAD metabolism - - - 0.000000000000000002029 97.0
HKD1_k127_7735400_8 Beta-L-arabinofuranosidase, GH127 K09955 - - 7.261e-223 709.0
HKD1_k127_7735400_80 response regulator, receiver - - - 0.00000000000000001363 94.0
HKD1_k127_7735400_81 - - - - 0.00000000000000002238 93.0
HKD1_k127_7735400_82 - - - - 0.0000000000000001057 83.0
HKD1_k127_7735400_83 - - - - 0.0000000000001373 82.0
HKD1_k127_7735400_84 23S rRNA-intervening sequence protein - - - 0.000000000001279 74.0
HKD1_k127_7735400_85 - - - - 0.00000000003244 75.0
HKD1_k127_7735400_86 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000005713 68.0
HKD1_k127_7735400_87 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000006162 70.0
HKD1_k127_7735400_88 Protein of unknown function (DUF1326) - - - 0.000000002915 69.0
HKD1_k127_7735400_89 Cupin 2, conserved barrel domain protein - - - 0.000000004842 66.0
HKD1_k127_7735400_9 cellulose binding - - - 5.469e-216 673.0
HKD1_k127_7735400_90 - - - - 0.00000002658 64.0
HKD1_k127_7735400_91 Regulatory protein, FmdB family - - - 0.00000003618 58.0
HKD1_k127_7735400_92 Acetyltransferase (GNAT) domain K00663,K03790 - 2.3.1.128,2.3.1.82 0.00000009415 61.0
HKD1_k127_7735400_93 Protein of unknown function (DUF2959) - - - 0.0000003846 60.0
HKD1_k127_7735400_94 Carotene biosynthesis associated membrane protein K14337,K14339 GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000009336 58.0
HKD1_k127_7735400_95 Domain of unknown function (DUF4390) - - - 0.000009603 54.0
HKD1_k127_7735400_96 - - - - 0.00008545 51.0
HKD1_k127_7735400_98 Di-haem oxidoreductase, putative peroxidase - - - 0.0009165 42.0
HKD1_k127_774730_0 AcrB/AcrD/AcrF family - - - 0.0 1157.0
HKD1_k127_774730_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 356.0
HKD1_k127_774730_10 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000002458 134.0
HKD1_k127_774730_11 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000000000000001509 115.0
HKD1_k127_774730_12 MacB-like periplasmic core domain - - - 0.0000000001896 66.0
HKD1_k127_774730_13 Nucleotide binding protein, PINc - - - 0.00000001066 61.0
HKD1_k127_774730_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 320.0
HKD1_k127_774730_3 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 336.0
HKD1_k127_774730_4 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001142 251.0
HKD1_k127_774730_5 aminotransferase K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000004331 221.0
HKD1_k127_774730_6 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000005961 180.0
HKD1_k127_774730_7 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000002903 174.0
HKD1_k127_774730_8 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000001729 155.0
HKD1_k127_774730_9 - - - - 0.000000000000000000000000000000000000006103 150.0
HKD1_k127_7748247_0 aminopeptidase activity K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 542.0
HKD1_k127_7748247_1 protein homotetramerization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003484 269.0
HKD1_k127_7748247_2 Membrane - - - 0.0000000000000000000000000000000000000000000000000001238 206.0
HKD1_k127_7748247_3 NIPSNAP - - - 0.0000000000000000000000000000000000000007773 153.0
HKD1_k127_7748247_4 N-acetyltransferase K00675 - 2.3.1.118 0.00000000000000000000000253 108.0
HKD1_k127_7748247_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000002217 104.0
HKD1_k127_7825792_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1113.0
HKD1_k127_7825792_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1097.0
HKD1_k127_7825792_10 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 496.0
HKD1_k127_7825792_11 protease-associated PA domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008827 505.0
HKD1_k127_7825792_12 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 500.0
HKD1_k127_7825792_13 Mo-co oxidoreductase dimerisation domain K17225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 471.0
HKD1_k127_7825792_14 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 466.0
HKD1_k127_7825792_15 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 398.0
HKD1_k127_7825792_16 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 391.0
HKD1_k127_7825792_17 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 364.0
HKD1_k127_7825792_18 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 353.0
HKD1_k127_7825792_19 Dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 323.0
HKD1_k127_7825792_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.583e-224 708.0
HKD1_k127_7825792_20 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 309.0
HKD1_k127_7825792_21 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 292.0
HKD1_k127_7825792_22 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 295.0
HKD1_k127_7825792_23 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278,K00767 - 1.4.3.16,2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000002771 260.0
HKD1_k127_7825792_24 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000005376 247.0
HKD1_k127_7825792_25 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000002636 251.0
HKD1_k127_7825792_26 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000007215 239.0
HKD1_k127_7825792_27 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000001134 235.0
HKD1_k127_7825792_28 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000003006 214.0
HKD1_k127_7825792_29 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000004476 218.0
HKD1_k127_7825792_3 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 1.488e-208 666.0
HKD1_k127_7825792_30 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000002164 199.0
HKD1_k127_7825792_31 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000009881 206.0
HKD1_k127_7825792_32 Cytidylate kinase-like family K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000002733 201.0
HKD1_k127_7825792_33 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000000000000000000001821 196.0
HKD1_k127_7825792_34 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000004652 195.0
HKD1_k127_7825792_35 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000000000000000000000000000000000000000000003843 188.0
HKD1_k127_7825792_36 Peptidase family M50 K06402 - - 0.0000000000000000000000000000000000000000000000000209 186.0
HKD1_k127_7825792_37 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000002156 181.0
HKD1_k127_7825792_38 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000005343 183.0
HKD1_k127_7825792_39 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.00000000000000000000000000000000000000000000009239 175.0
HKD1_k127_7825792_4 Ribosomal protein S1 K02945 - - 2.358e-206 661.0
HKD1_k127_7825792_40 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000002428 174.0
HKD1_k127_7825792_41 PFAM glutamine amidotransferase class-I K07010 - - 0.00000000000000000000000000000000000000000000291 172.0
HKD1_k127_7825792_42 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000005649 166.0
HKD1_k127_7825792_43 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000001391 159.0
HKD1_k127_7825792_44 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000000004242 134.0
HKD1_k127_7825792_45 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000219 143.0
HKD1_k127_7825792_46 Tetratricopeptide repeat - - - 0.00000000000000000000000000000002239 145.0
HKD1_k127_7825792_47 - - - - 0.000000000000000000000000000001864 139.0
HKD1_k127_7825792_48 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000643 119.0
HKD1_k127_7825792_49 oxidoreductase activity - - - 0.0000000000000000000000000007237 132.0
HKD1_k127_7825792_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 596.0
HKD1_k127_7825792_50 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000000000000000000000002116 110.0
HKD1_k127_7825792_51 AraC-like ligand binding domain - - - 0.000000000000000000000009563 113.0
HKD1_k127_7825792_52 - - - - 0.00000000000000006914 89.0
HKD1_k127_7825792_53 oxidoreductase activity - - - 0.000000000044 76.0
HKD1_k127_7825792_55 HEAT repeats - - - 0.000001385 61.0
HKD1_k127_7825792_56 cell adhesion - - - 0.000001509 59.0
HKD1_k127_7825792_57 domain, Protein K01179 - 3.2.1.4 0.0001217 53.0
HKD1_k127_7825792_58 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0002298 52.0
HKD1_k127_7825792_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 565.0
HKD1_k127_7825792_7 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 541.0
HKD1_k127_7825792_8 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 526.0
HKD1_k127_7825792_9 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 538.0
HKD1_k127_7869738_0 MacB-like periplasmic core domain - - - 0.0 1028.0
HKD1_k127_7869738_1 Dehydrogenase K00114,K17760,K20936,K21676,K22473 - 1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2 1.864e-261 829.0
HKD1_k127_7869738_10 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 417.0
HKD1_k127_7869738_11 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 398.0
HKD1_k127_7869738_12 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 398.0
HKD1_k127_7869738_13 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 385.0
HKD1_k127_7869738_14 protein kinase activity K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 370.0
HKD1_k127_7869738_15 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 356.0
HKD1_k127_7869738_16 PFAM ABC transporter K01990,K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 321.0
HKD1_k127_7869738_17 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 299.0
HKD1_k127_7869738_18 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002138 282.0
HKD1_k127_7869738_19 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004129 269.0
HKD1_k127_7869738_2 Peptidase family M3 K01392 - 3.4.24.15 8.045e-219 699.0
HKD1_k127_7869738_20 tRNA pseudouridine synthase K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000003716 263.0
HKD1_k127_7869738_21 transport, permease protein K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001822 270.0
HKD1_k127_7869738_22 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001773 271.0
HKD1_k127_7869738_23 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003784 278.0
HKD1_k127_7869738_24 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005318 261.0
HKD1_k127_7869738_25 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000001184 254.0
HKD1_k127_7869738_26 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004053 245.0
HKD1_k127_7869738_27 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000001376 235.0
HKD1_k127_7869738_28 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001171 221.0
HKD1_k127_7869738_29 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000006805 217.0
HKD1_k127_7869738_3 carbamoyl transferase, NodU family K00612 - - 2.304e-200 642.0
HKD1_k127_7869738_30 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000001429 198.0
HKD1_k127_7869738_31 - - - - 0.000000000000000000000000000000000000000000000000002189 200.0
HKD1_k127_7869738_32 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000002198 187.0
HKD1_k127_7869738_33 Glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000002655 195.0
HKD1_k127_7869738_34 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000002807 178.0
HKD1_k127_7869738_35 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000001815 171.0
HKD1_k127_7869738_36 - - - - 0.00000000000000000000000000000000000000007741 170.0
HKD1_k127_7869738_37 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000009026 147.0
HKD1_k127_7869738_38 methyltransferase - - - 0.0000000000000000000000000000000000007733 151.0
HKD1_k127_7869738_39 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.000000000000000000000000000000000004264 150.0
HKD1_k127_7869738_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 553.0
HKD1_k127_7869738_40 cytochrome C peroxidase - - - 0.00000000000000000000000000000000002089 141.0
HKD1_k127_7869738_41 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000002736 141.0
HKD1_k127_7869738_42 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000319 147.0
HKD1_k127_7869738_43 geranylgeranyl reductase K00311 - 1.5.5.1 0.0000000000000000000000000000000001202 148.0
HKD1_k127_7869738_44 Polysaccharide export protein K01991,K20988 - - 0.000000000000000000000000000000000145 146.0
HKD1_k127_7869738_45 Histidine kinase - - - 0.0000000000000000000000000000000003175 146.0
HKD1_k127_7869738_46 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000002824 141.0
HKD1_k127_7869738_47 Glycosyl transferases group 1 - - - 0.0000000000000000000000000002425 128.0
HKD1_k127_7869738_48 O-Antigen ligase K02847 - - 0.00000000000000000000000001478 124.0
HKD1_k127_7869738_49 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000007997 116.0
HKD1_k127_7869738_5 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 562.0
HKD1_k127_7869738_50 efflux transmembrane transporter activity - - - 0.0000000000000000000000008046 107.0
HKD1_k127_7869738_51 negative regulation of transcription, DNA-templated K10947 - - 0.00000000000000000000000272 106.0
HKD1_k127_7869738_52 Polysaccharide deacetylase - - - 0.0000000000000000000001163 111.0
HKD1_k127_7869738_53 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000003006 109.0
HKD1_k127_7869738_54 Helix-hairpin-helix motif - - - 0.000000000000000000001003 99.0
HKD1_k127_7869738_55 Glycosyl transferase, family 2 - - - 0.000000000000006201 87.0
HKD1_k127_7869738_56 membrane - - - 0.0000000000000207 84.0
HKD1_k127_7869738_57 YjbR - - - 0.00000000000002689 82.0
HKD1_k127_7869738_58 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000004067 85.0
HKD1_k127_7869738_59 Glycosyl transferase, family 2 K07011,K13005 - 2.4.1.60 0.0000000000006904 79.0
HKD1_k127_7869738_6 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 529.0
HKD1_k127_7869738_60 Matrix metalloproteinase-20 K07999 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0009653,GO:0009887,GO:0009987,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022603,GO:0022617,GO:0030163,GO:0030198,GO:0030574,GO:0032501,GO:0032502,GO:0032963,GO:0042475,GO:0042476,GO:0042481,GO:0042487,GO:0043062,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044421,GO:0046872,GO:0046914,GO:0048513,GO:0048646,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0051239,GO:0065007,GO:0070011,GO:0070167,GO:0070170,GO:0070173,GO:0071704,GO:0071840,GO:0097186,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:2000026,GO:2000027 - 0.0000000001574 72.0
HKD1_k127_7869738_61 - - - - 0.000000004748 63.0
HKD1_k127_7869738_62 ABC-type antimicrobial peptide transport system, permease component - - - 0.00000006543 57.0
HKD1_k127_7869738_63 - - - - 0.000002907 54.0
HKD1_k127_7869738_64 Methyltransferase FkbM domain - - - 0.0001179 51.0
HKD1_k127_7869738_7 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 520.0
HKD1_k127_7869738_8 Belongs to the alpha-IPM synthase homocitrate synthase family K01649,K02594,K09011 - 2.3.1.182,2.3.3.13,2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 489.0
HKD1_k127_7869738_9 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 432.0
HKD1_k127_7883144_0 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.0 1069.0
HKD1_k127_7883144_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.357e-278 867.0
HKD1_k127_7883144_10 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000009144 187.0
HKD1_k127_7883144_11 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000001734 184.0
HKD1_k127_7883144_12 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000007626 164.0
HKD1_k127_7883144_13 Flavodoxin - - - 0.0000000000000000000000000000000000000000002358 164.0
HKD1_k127_7883144_14 - - - - 0.000000000000000000007879 106.0
HKD1_k127_7883144_15 Polymer-forming cytoskeletal - - - 0.0000000000000000007296 100.0
HKD1_k127_7883144_16 Phosphopantetheine attachment site - - - 0.000000000000000001082 96.0
HKD1_k127_7883144_17 ABC 3 transport family K09816 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - 0.0000000000006275 79.0
HKD1_k127_7883144_18 Domain of unknown function DUF302 - - - 0.000000001066 68.0
HKD1_k127_7883144_19 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000007996 65.0
HKD1_k127_7883144_2 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 503.0
HKD1_k127_7883144_20 - - - - 0.000002636 59.0
HKD1_k127_7883144_3 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 494.0
HKD1_k127_7883144_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 448.0
HKD1_k127_7883144_5 S-acyltransferase activity K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 434.0
HKD1_k127_7883144_6 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 417.0
HKD1_k127_7883144_7 non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001708 259.0
HKD1_k127_7883144_8 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000005278 233.0
HKD1_k127_7883144_9 PFAM ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000001634 220.0