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Overview

ID MAG01716
Name HKD1_bin.32
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Rhizobiales
Family Xanthobacteraceae
Genus Pseudolabrys
Species
Assembly information
Completeness (%) 74.57
Contamination (%) 3.02
GC content (%) 61.0
N50 (bp) 9,036
Genome size (bp) 3,120,088

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3213

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1002813_0 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 374.0
HKD1_k127_1002813_1 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 337.0
HKD1_k127_1002813_2 Belongs to the carbohydrate kinase PfkB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007352 274.0
HKD1_k127_1002813_3 PFAM glycosyl transferase family 9 K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007491 253.0
HKD1_k127_1005825_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 4.592e-312 964.0
HKD1_k127_1005825_1 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 500.0
HKD1_k127_1005825_2 Belongs to the IlvD Edd family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 436.0
HKD1_k127_1005825_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000002664 64.0
HKD1_k127_1007555_0 Putative peptidoglycan binding domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 501.0
HKD1_k127_1007555_1 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000001116 199.0
HKD1_k127_101531_0 Protein of unknown function (DUF3168) - - - 0.0000000000000000000000000000000000000000000000000000000000001335 214.0
HKD1_k127_101531_1 Phage gp6-like head-tail connector protein - - - 0.0000000000000000000000000000000000000000000000000000000006545 207.0
HKD1_k127_101531_2 Phage head-tail joining protein - - - 0.000000000000000000001004 104.0
HKD1_k127_1027510_0 Sigma-54 interaction domain K13599 - - 2.919e-247 768.0
HKD1_k127_1027510_1 Amino-transferase class IV K00824 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 376.0
HKD1_k127_1027510_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000003225 207.0
HKD1_k127_103028_0 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 1.406e-283 879.0
HKD1_k127_103028_1 FMN_bind K19339,K19343 - - 1.785e-220 692.0
HKD1_k127_103028_10 oxygen carrier activity K07216 - - 0.0000000000000000000000000000001689 127.0
HKD1_k127_103028_11 cytochrome c oxidase (Subunit II) - - - 0.00008702 45.0
HKD1_k127_103028_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 602.0
HKD1_k127_103028_3 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 403.0
HKD1_k127_103028_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 358.0
HKD1_k127_103028_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 306.0
HKD1_k127_103028_6 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000007797 241.0
HKD1_k127_103028_7 Domain of unknown function (DUF4202) - - - 0.0000000000000000000000000000000000000000000000000000001825 200.0
HKD1_k127_103028_8 Cytochrome c K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000003072 188.0
HKD1_k127_103028_9 - - - - 0.0000000000000000000000000000000000473 139.0
HKD1_k127_1035645_0 ABC transporter K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 1.269e-311 965.0
HKD1_k127_1035645_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 6.822e-296 919.0
HKD1_k127_1035645_10 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 429.0
HKD1_k127_1035645_11 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 397.0
HKD1_k127_1035645_12 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 390.0
HKD1_k127_1035645_13 lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 389.0
HKD1_k127_1035645_14 HWE histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 370.0
HKD1_k127_1035645_15 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 362.0
HKD1_k127_1035645_16 CDP-alcohol phosphatidyltransferase K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 364.0
HKD1_k127_1035645_17 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 330.0
HKD1_k127_1035645_18 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 327.0
HKD1_k127_1035645_19 Kelch repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 314.0
HKD1_k127_1035645_2 Acyl-CoA reductase (LuxC) K00140 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896 1.2.1.18,1.2.1.27 3.152e-288 889.0
HKD1_k127_1035645_20 myo-inosose-2 dehydratase activity K00457,K06606 - 1.13.11.27,5.3.99.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 290.0
HKD1_k127_1035645_21 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001801 277.0
HKD1_k127_1035645_22 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009382 278.0
HKD1_k127_1035645_23 FabA-like domain K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000001215 204.0
HKD1_k127_1035645_24 PFAM General substrate transporter K08369 - - 0.0000000000000000000000000000000000000000000000000000005761 207.0
HKD1_k127_1035645_25 Phosphopantetheine attachment site - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000002964 177.0
HKD1_k127_1035645_26 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000001881 180.0
HKD1_k127_1035645_27 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000009698 175.0
HKD1_k127_1035645_28 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000000000000000001033 178.0
HKD1_k127_1035645_29 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000122 171.0
HKD1_k127_1035645_3 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 4.766e-285 887.0
HKD1_k127_1035645_30 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000004214 165.0
HKD1_k127_1035645_31 Low affinity iron permease - - - 0.000000000000000000000000000000000003058 142.0
HKD1_k127_1035645_32 Lytic transglycolase K03642 - - 0.0000000000000000000000006691 110.0
HKD1_k127_1035645_33 - - - - 0.000000000000000000000006865 105.0
HKD1_k127_1035645_34 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000001232 100.0
HKD1_k127_1035645_35 UPF0391 membrane protein - - - 0.000000000000000000791 89.0
HKD1_k127_1035645_36 - - - - 0.0000000000000000009377 89.0
HKD1_k127_1035645_37 - - - - 0.000000002439 60.0
HKD1_k127_1035645_4 DNA ligase K01971 - 6.5.1.1 6.049e-283 893.0
HKD1_k127_1035645_5 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 7.594e-200 629.0
HKD1_k127_1035645_6 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 555.0
HKD1_k127_1035645_7 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 541.0
HKD1_k127_1035645_8 synthase K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 538.0
HKD1_k127_1035645_9 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 522.0
HKD1_k127_1035771_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1283.0
HKD1_k127_1035771_1 Voltage gated chloride channel K03281 - - 3.306e-220 697.0
HKD1_k127_1035771_10 - - - - 0.0000000000000000000004158 100.0
HKD1_k127_1035771_2 Rieske [2Fe-2S] domain - - - 3.02e-212 666.0
HKD1_k127_1035771_3 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 8.34e-210 662.0
HKD1_k127_1035771_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 6.003e-205 641.0
HKD1_k127_1035771_5 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 489.0
HKD1_k127_1035771_6 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 367.0
HKD1_k127_1035771_7 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 355.0
HKD1_k127_1035771_8 pfkB family carbohydrate kinase K00847,K00856 - 2.7.1.20,2.7.1.4 0.00000000000000000000000000000000000000004859 154.0
HKD1_k127_1035771_9 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000003455 108.0
HKD1_k127_1041428_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1133.0
HKD1_k127_1041428_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 538.0
HKD1_k127_1041428_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000004069 260.0
HKD1_k127_1041428_3 AI-2E family transporter K03548 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001071 256.0
HKD1_k127_1041428_4 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000004219 218.0
HKD1_k127_1041428_5 methylamine metabolic process K03885,K15977 - 1.6.99.3 0.000000000000000000000000003216 117.0
HKD1_k127_1041428_6 DoxX K15977 - - 0.000000000000000000000000005539 116.0
HKD1_k127_1041428_7 PFAM DoxX family protein K15977 - - 0.00000000000000000004293 96.0
HKD1_k127_1044317_0 Heat shock 70 kDa protein K04043 - - 0.0 1102.0
HKD1_k127_1044317_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 604.0
HKD1_k127_1044317_10 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001045 245.0
HKD1_k127_1044317_11 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000008956 236.0
HKD1_k127_1044317_12 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000001294 215.0
HKD1_k127_1044317_13 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000000000000000000000000000000001065 203.0
HKD1_k127_1044317_14 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000000000000000127 184.0
HKD1_k127_1044317_15 - - - - 0.00000000000000000000000000000000000000000000000004059 192.0
HKD1_k127_1044317_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 545.0
HKD1_k127_1044317_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 443.0
HKD1_k127_1044317_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 410.0
HKD1_k127_1044317_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 360.0
HKD1_k127_1044317_6 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 355.0
HKD1_k127_1044317_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 351.0
HKD1_k127_1044317_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 327.0
HKD1_k127_1044317_9 Ribosomal RNA adenine dimethylase K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 292.0
HKD1_k127_1059011_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1111.0
HKD1_k127_1059011_1 NLP P60 protein - - - 1.118e-273 856.0
HKD1_k127_1059011_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000001312 202.0
HKD1_k127_1059011_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000001025 144.0
HKD1_k127_106460_0 Cobalamin biosynthesis protein CobT VWA domain K09883 - 6.6.1.2 2.595e-301 934.0
HKD1_k127_106460_1 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 3.614e-198 621.0
HKD1_k127_106460_10 PFAM heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001423 269.0
HKD1_k127_106460_11 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000003337 231.0
HKD1_k127_106460_12 Belongs to the BolA IbaG family K05527,K22066 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - 0.000000000000000000000000000000000000001189 148.0
HKD1_k127_106460_13 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000369 141.0
HKD1_k127_106460_14 - - - - 0.00000000008676 72.0
HKD1_k127_106460_2 Transporter associated domain K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 589.0
HKD1_k127_106460_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 513.0
HKD1_k127_106460_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 501.0
HKD1_k127_106460_5 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 460.0
HKD1_k127_106460_6 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 406.0
HKD1_k127_106460_7 Esterase-like activity of phytase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 330.0
HKD1_k127_106460_8 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 294.0
HKD1_k127_106460_9 helicase superfamily c-terminal domain K17675 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003407 277.0
HKD1_k127_1066076_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 6.557e-304 942.0
HKD1_k127_1066076_1 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 454.0
HKD1_k127_1066076_2 Transglycosylase SLT domain K00786,K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 391.0
HKD1_k127_1066076_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 287.0
HKD1_k127_1066076_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000002419 259.0
HKD1_k127_1071288_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 9.33e-236 745.0
HKD1_k127_1071288_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 546.0
HKD1_k127_1071288_2 hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 372.0
HKD1_k127_1071288_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 349.0
HKD1_k127_1071288_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004142 256.0
HKD1_k127_1071288_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000005953 245.0
HKD1_k127_1071288_6 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000001078 236.0
HKD1_k127_1071288_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000002137 161.0
HKD1_k127_1072068_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1288.0
HKD1_k127_1072068_1 Protein of unknown function (DUF3096) - - - 0.0000000006458 60.0
HKD1_k127_1079282_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1253.0
HKD1_k127_1079282_1 Flavin-binding monooxygenase-like K07222 - - 1.398e-209 666.0
HKD1_k127_1079282_2 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 286.0
HKD1_k127_1079282_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001264 250.0
HKD1_k127_1079282_4 - - - - 0.00000000000000000000000000000000000000000000008272 178.0
HKD1_k127_1083214_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 2.064e-306 952.0
HKD1_k127_1083214_1 FAD dependent oxidoreductase - - - 1.405e-247 773.0
HKD1_k127_1083214_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 521.0
HKD1_k127_1083214_3 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 516.0
HKD1_k127_1083214_4 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 430.0
HKD1_k127_1083214_5 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 397.0
HKD1_k127_1083214_6 Squalene/phytoene synthase K21678,K21679 - 2.5.1.103,4.2.3.156 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 344.0
HKD1_k127_1083214_7 Squalene/phytoene synthase K02291,K21678 - 2.5.1.103,2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 317.0
HKD1_k127_1094716_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 4.546e-257 801.0
HKD1_k127_1094716_1 Beta-Casp domain K07576 - - 1.051e-224 702.0
HKD1_k127_1110933_0 ABC transporter K15738 - - 2.323e-320 987.0
HKD1_k127_1110933_1 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 594.0
HKD1_k127_1110933_10 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000001059 205.0
HKD1_k127_1110933_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000004201 190.0
HKD1_k127_1110933_12 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000008406 160.0
HKD1_k127_1110933_13 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03574 - 3.6.1.55 0.0000000000000000000000000000000000005357 147.0
HKD1_k127_1110933_14 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.0000000000000000000000000000005077 123.0
HKD1_k127_1110933_15 N-terminal region of glycosyl transferase group 7 - - - 0.000000000000000000000000000001943 130.0
HKD1_k127_1110933_16 Domain of Unknown Function (DUF930) - - - 0.000000000000000000000000000004737 125.0
HKD1_k127_1110933_17 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000009174 104.0
HKD1_k127_1110933_18 - - - - 0.00000000000000000000003807 105.0
HKD1_k127_1110933_19 Uncharacterized protein conserved in bacteria (DUF2314) - - - 0.000000000000000000000214 104.0
HKD1_k127_1110933_2 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 509.0
HKD1_k127_1110933_21 - - - - 0.0000000000002844 74.0
HKD1_k127_1110933_22 - - - - 0.000000000002035 70.0
HKD1_k127_1110933_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008974 329.0
HKD1_k127_1110933_4 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 296.0
HKD1_k127_1110933_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 297.0
HKD1_k127_1110933_6 Phosphatidylethanolamine-binding protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004208 278.0
HKD1_k127_1110933_7 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009254 260.0
HKD1_k127_1110933_8 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003586 260.0
HKD1_k127_1110933_9 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000003246 226.0
HKD1_k127_1124235_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 392.0
HKD1_k127_1124235_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 325.0
HKD1_k127_1124235_2 - - - - 0.000003884 52.0
HKD1_k127_1126764_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 5.431e-199 628.0
HKD1_k127_1126764_1 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000006366 193.0
HKD1_k127_1126764_2 Protein of unknown function (FYDLN_acid) - - - 0.0000000000000000000000000007735 117.0
HKD1_k127_1126764_3 proteins, homologs of microcin C7 resistance protein MccF - - - 0.000000000000000001932 85.0
HKD1_k127_1126950_0 dehydratase K14449 GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 532.0
HKD1_k127_1126950_1 PFAM regulatory protein LysR K11921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 381.0
HKD1_k127_1126950_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000002914 194.0
HKD1_k127_1126950_3 Protein of unknown function (DUF1109) - - - 0.000003014 53.0
HKD1_k127_1129614_0 Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 311.0
HKD1_k127_1129614_1 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000001458 211.0
HKD1_k127_1129614_2 Protein affecting phage T7 exclusion by the F plasmid K07113 - - 0.000000000000007998 80.0
HKD1_k127_1129614_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000004359 64.0
HKD1_k127_1129614_4 membrane-bound lytic murein transglycosylase K08304 - - 0.00009998 48.0
HKD1_k127_113627_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 3.418e-213 665.0
HKD1_k127_113627_1 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 454.0
HKD1_k127_113627_2 Acyl-CoA dehydrogenase, C-terminal domain K14448 - 1.3.8.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 368.0
HKD1_k127_113627_3 Protein required for attachment to host cells - - - 0.00000000000000000000000000000000000000000000000003987 182.0
HKD1_k127_1138821_0 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.0 1044.0
HKD1_k127_1138821_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 8.552e-253 783.0
HKD1_k127_1138821_10 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.000000000000000000000000000000000009934 138.0
HKD1_k127_1138821_11 Ribonuclease B OB domain K03704 - - 0.000000000000000000000000000006098 122.0
HKD1_k127_1138821_12 - - - - 0.000008758 48.0
HKD1_k127_1138821_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 602.0
HKD1_k127_1138821_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 525.0
HKD1_k127_1138821_4 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 509.0
HKD1_k127_1138821_5 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 479.0
HKD1_k127_1138821_6 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 465.0
HKD1_k127_1138821_7 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 408.0
HKD1_k127_1138821_8 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 289.0
HKD1_k127_1138821_9 L-carnitine dehydratase bile acid-inducible protein F K07749 GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0047369 2.8.3.16 0.00000000000000000000000000000000000000000001337 163.0
HKD1_k127_1153938_0 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 494.0
HKD1_k127_1153938_1 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 379.0
HKD1_k127_1153938_10 - - - - 0.0000000000001088 74.0
HKD1_k127_1153938_11 - - - - 0.00004156 46.0
HKD1_k127_1153938_12 - - - - 0.00004389 46.0
HKD1_k127_1153938_13 - - - - 0.00005869 48.0
HKD1_k127_1153938_2 Cold shock protein domain K03704 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 332.0
HKD1_k127_1153938_3 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001148 272.0
HKD1_k127_1153938_4 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002975 274.0
HKD1_k127_1153938_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000922 247.0
HKD1_k127_1153938_6 - - - - 0.0000000000000000000000000000000000000000000000000000000343 205.0
HKD1_k127_1153938_7 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000007751 190.0
HKD1_k127_1153938_8 ETC complex I subunit conserved region K00329 - 1.6.5.3 0.00000000000000000000000000000000000001094 148.0
HKD1_k127_1153938_9 - - - - 0.000000000000000000000003003 111.0
HKD1_k127_1160773_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0 1036.0
HKD1_k127_1160773_1 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 4.34e-294 931.0
HKD1_k127_1160773_2 PAS fold - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 6.084e-289 908.0
HKD1_k127_1160773_3 Phosphotransferase enzyme family K07102 - 2.7.1.221 9.823e-203 643.0
HKD1_k127_1160773_4 Nucleotidyl transferase K00966,K00992 - 2.7.7.13,2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 339.0
HKD1_k127_1170654_0 FAD binding domain K20940 - 1.14.13.218 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 580.0
HKD1_k127_1170654_1 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000005547 234.0
HKD1_k127_1170654_2 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002732 241.0
HKD1_k127_1170654_3 Protein of unknown function (DUF1272) K09984 - - 0.0000000000000000000000000000000000000000000000001706 178.0
HKD1_k127_1170654_4 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000001593 156.0
HKD1_k127_1170654_5 Disulfide bond formation protein DsbB K03611 - - 0.00000000000000000000000000000000002466 137.0
HKD1_k127_1179528_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 7.105e-292 903.0
HKD1_k127_1179528_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 6.295e-204 639.0
HKD1_k127_1179528_2 Belongs to the thiolase family K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0033554,GO:0033812,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0071944,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 589.0
HKD1_k127_1179528_3 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 546.0
HKD1_k127_1179528_4 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999,K11959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 466.0
HKD1_k127_1179528_5 Luciferase-like monooxygenase K15854 - 1.14.14.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 345.0
HKD1_k127_1187953_0 FAD linked oxidases, C-terminal domain K00004,K00102 GO:0003674,GO:0003824,GO:0004457,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008720,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.1.1.303,1.1.1.4,1.1.2.4 7.401e-224 703.0
HKD1_k127_1187953_1 AsmA-like C-terminal region K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 366.0
HKD1_k127_1187953_2 methyltransferase activity K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 351.0
HKD1_k127_1187953_3 Protein of unknown function (DUF3455) - - - 0.000000000000000000000000000000000000000000000000000023 196.0
HKD1_k127_1203823_0 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component K00380 - 1.8.1.2 2.266e-218 692.0
HKD1_k127_1203823_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366,K02229 - 1.14.13.83,1.7.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 436.0
HKD1_k127_1216166_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 3.021e-198 627.0
HKD1_k127_1216166_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000001517 79.0
HKD1_k127_1216399_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 5.166e-213 674.0
HKD1_k127_1216399_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 567.0
HKD1_k127_1216399_10 Bacterial SH3 domain K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000005535 227.0
HKD1_k127_1216399_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 420.0
HKD1_k127_1216399_3 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 415.0
HKD1_k127_1216399_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 384.0
HKD1_k127_1216399_5 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 361.0
HKD1_k127_1216399_6 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 329.0
HKD1_k127_1216399_7 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 335.0
HKD1_k127_1216399_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 301.0
HKD1_k127_1216399_9 Belongs to the Fur family K09826 - - 0.0000000000000000000000000000000000000000000000000000000000000000000537 234.0
HKD1_k127_123027_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1002.0
HKD1_k127_123027_1 PFAM regulatory protein LysR K11921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 432.0
HKD1_k127_123027_2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000002965 183.0
HKD1_k127_123027_3 MaoC like domain K14449 GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.000000000000000000000000000000000000000000001699 165.0
HKD1_k127_123027_4 succinate dehydrogenase K00242 - - 0.00000000000000000000000000000000006014 140.0
HKD1_k127_1240761_0 Nitrate reductase beta subunit K00371 - 1.7.5.1 8.521e-314 964.0
HKD1_k127_1240761_1 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 328.0
HKD1_k127_1240761_2 Nitrate reductase delta subunit K00373 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005301 263.0
HKD1_k127_1240761_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000006665 216.0
HKD1_k127_1243469_0 ABC transporter K06147,K11085 - - 3.655e-259 811.0
HKD1_k127_1243469_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 458.0
HKD1_k127_1243469_2 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 391.0
HKD1_k127_1243469_3 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 361.0
HKD1_k127_1243469_4 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 353.0
HKD1_k127_1243469_5 PFAM glycosyl transferase family 9 K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 351.0
HKD1_k127_1243469_6 Branched-chain amino acid ATP-binding cassette transporter K01995,K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 351.0
HKD1_k127_1243469_7 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 347.0
HKD1_k127_1243469_8 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 348.0
HKD1_k127_1253636_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 518.0
HKD1_k127_1253636_1 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000366 278.0
HKD1_k127_1253636_2 YtkA-like - - - 0.000000000000000000000000000000000000000000000001752 176.0
HKD1_k127_1255443_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003148 257.0
HKD1_k127_1255443_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP - - - 0.0000000000000000000000000000000000000000000000000000000000000000007333 232.0
HKD1_k127_1255443_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000002704 215.0
HKD1_k127_1255443_3 ABC transporter K01995,K01996 - - 0.000000000000000000000000000000000000000000000000000002772 206.0
HKD1_k127_1255443_4 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000002373 187.0
HKD1_k127_1255443_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000001487 159.0
HKD1_k127_1260290_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001985 265.0
HKD1_k127_1260290_1 DoxX K15977 - - 0.000000000000000000000000000000001503 134.0
HKD1_k127_1260290_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000007588 51.0
HKD1_k127_1263636_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 472.0
HKD1_k127_1263636_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 371.0
HKD1_k127_1263636_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002435 264.0
HKD1_k127_1263636_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001083 261.0
HKD1_k127_1263636_4 carbohydrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000003059 232.0
HKD1_k127_1263636_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000001898 147.0
HKD1_k127_1263636_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000003601 105.0
HKD1_k127_1264979_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.02e-317 985.0
HKD1_k127_1264979_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 605.0
HKD1_k127_1264979_2 Belongs to the phosphoglycerate kinase family K00927 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 558.0
HKD1_k127_1264979_3 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 487.0
HKD1_k127_1264979_4 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 436.0
HKD1_k127_1264979_5 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 383.0
HKD1_k127_1264979_6 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000008605 210.0
HKD1_k127_1264979_7 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000005622 170.0
HKD1_k127_1264979_8 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000000002887 138.0
HKD1_k127_1264979_9 Domain of unknown function (DUF4164) - - - 0.00000000000000000000302 95.0
HKD1_k127_1279857_0 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000259 241.0
HKD1_k127_1279857_1 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000003665 220.0
HKD1_k127_12879_0 Terminase RNaseH-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 569.0
HKD1_k127_12879_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 479.0
HKD1_k127_12879_10 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000000000000000000008604 203.0
HKD1_k127_12879_11 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000001338 181.0
HKD1_k127_12879_12 - - - - 0.000000000000000000000000000000000000000000002954 168.0
HKD1_k127_12879_13 YCII-related domain - - - 0.00000000000000000000000002487 111.0
HKD1_k127_12879_14 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000007577 114.0
HKD1_k127_12879_15 Eukaryotic cytochrome b561 - - - 0.000000000000000000000006518 115.0
HKD1_k127_12879_16 - - - - 0.0000000000000000000004301 106.0
HKD1_k127_12879_17 SPW repeat - - - 0.00000000000002776 77.0
HKD1_k127_12879_18 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific - - - 0.0007658 47.0
HKD1_k127_12879_2 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 420.0
HKD1_k127_12879_3 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 377.0
HKD1_k127_12879_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 362.0
HKD1_k127_12879_5 ABC-type transport auxiliary lipoprotein component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 368.0
HKD1_k127_12879_6 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 347.0
HKD1_k127_12879_7 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001149 281.0
HKD1_k127_12879_8 Dienelactone hydrolase family K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001175 267.0
HKD1_k127_12879_9 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.000000000000000000000000000000000000000000000000000000002112 208.0
HKD1_k127_1288600_0 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 350.0
HKD1_k127_1288600_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 319.0
HKD1_k127_1288600_2 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000192 239.0
HKD1_k127_1288600_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000001152 228.0
HKD1_k127_1288600_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000003829 192.0
HKD1_k127_1314956_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 350.0
HKD1_k127_1314956_1 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 321.0
HKD1_k127_1314956_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007812 254.0
HKD1_k127_1314956_3 - - - - 0.00000000000000000000000000000000001147 138.0
HKD1_k127_1314956_4 cheY-homologous receiver domain - - - 0.000000000000000000000002993 107.0
HKD1_k127_1314956_5 Sulfatase-modifying factor enzyme 1 - - - 0.00000006473 55.0
HKD1_k127_1316410_0 DEAD/H associated K03724 - - 0.0 1272.0
HKD1_k127_1316410_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 511.0
HKD1_k127_1316410_2 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 375.0
HKD1_k127_1316410_3 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 334.0
HKD1_k127_1316410_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 321.0
HKD1_k127_1316410_5 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 286.0
HKD1_k127_1316410_6 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000001797 214.0
HKD1_k127_1316410_7 - - - - 0.000000000000000000000000000000006554 129.0
HKD1_k127_1318415_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 1.195e-264 825.0
HKD1_k127_1318415_1 Sodium/hydrogen exchanger family - - - 5.344e-236 754.0
HKD1_k127_1318415_2 H( )-stimulated, divalent metal cation uptake system K03322 - - 2.399e-209 662.0
HKD1_k127_1318415_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 567.0
HKD1_k127_1318415_4 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 427.0
HKD1_k127_1318415_5 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 366.0
HKD1_k127_1318415_6 RDD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005326 239.0
HKD1_k127_1318415_7 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000004505 180.0
HKD1_k127_1340209_0 phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 590.0
HKD1_k127_1340209_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 357.0
HKD1_k127_1340209_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001315 289.0
HKD1_k127_1340209_3 fibroblast growth factor binding - - - 0.0000000000000000000000000001651 125.0
HKD1_k127_1340209_4 - - - - 0.0000000001655 72.0
HKD1_k127_134397_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.384e-228 726.0
HKD1_k127_134397_1 Reductase C-terminal K05297 - 1.18.1.1 4.555e-226 710.0
HKD1_k127_134397_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 6.597e-199 624.0
HKD1_k127_134397_3 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 573.0
HKD1_k127_134397_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 569.0
HKD1_k127_134397_5 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 434.0
HKD1_k127_134397_6 enoyl-CoA hydratase K01692,K05605 - 3.1.2.4,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 417.0
HKD1_k127_134397_7 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 292.0
HKD1_k127_134397_8 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001269 241.0
HKD1_k127_134397_9 - - - - 0.00000000000000000000000000000000000000004416 156.0
HKD1_k127_1348058_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 404.0
HKD1_k127_1348058_1 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 400.0
HKD1_k127_1348058_2 Bacterial regulatory helix-turn-helix protein, lysR family K02623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 288.0
HKD1_k127_1348058_3 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001207 283.0
HKD1_k127_1348058_4 Belongs to the succinate malate CoA ligase beta subunit family K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001469 254.0
HKD1_k127_1348058_5 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000001012 198.0
HKD1_k127_1349996_0 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 342.0
HKD1_k127_1349996_1 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001571 279.0
HKD1_k127_1349996_2 Dehydrogenase K00055,K00121,K19653 - 1.1.1.1,1.1.1.284,1.1.1.347,1.1.1.90 0.00000000000000000000000000000000000001149 148.0
HKD1_k127_1349996_3 AMP-binding enzyme - - - 0.00000000000000007621 83.0
HKD1_k127_1354567_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 299.0
HKD1_k127_1354567_1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000001861 224.0
HKD1_k127_1354567_2 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001307 232.0
HKD1_k127_1354567_3 Tautomerase enzyme - - - 0.0000000000000000000000000000000000000000000000000000004351 195.0
HKD1_k127_1354567_4 PFAM 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000000000000991 118.0
HKD1_k127_1369555_0 CHAT domain - - - 0.0 1222.0
HKD1_k127_1369555_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 1.198e-267 832.0
HKD1_k127_1369555_10 Phosphopantetheine attachment site - - - 0.00002472 53.0
HKD1_k127_1369555_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 7.082e-226 705.0
HKD1_k127_1369555_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 529.0
HKD1_k127_1369555_4 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 467.0
HKD1_k127_1369555_5 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 443.0
HKD1_k127_1369555_6 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 425.0
HKD1_k127_1369555_7 COG1309 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007779 275.0
HKD1_k127_1369555_8 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000000000000000000000003113 231.0
HKD1_k127_1369555_9 Flp/Fap pilin component K02651 - - 0.0000000000000939 73.0
HKD1_k127_1383413_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.571e-237 737.0
HKD1_k127_1430696_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 395.0
HKD1_k127_1430696_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 342.0
HKD1_k127_1430696_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 297.0
HKD1_k127_1430696_3 Sporulation related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 291.0
HKD1_k127_1430696_4 - - - - 0.00000000000000000000000000000000000002777 145.0
HKD1_k127_1468542_0 COG0339 Zn-dependent oligopeptidases K01284 GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5 2.295e-301 938.0
HKD1_k127_1468542_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 6.509e-239 748.0
HKD1_k127_1468542_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 8.822e-238 749.0
HKD1_k127_1468542_3 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 335.0
HKD1_k127_1468542_4 Belongs to the NiCoT transporter (TC 2.A.52) family K08970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 343.0
HKD1_k127_1468542_5 Protein of unknown function (DUF1007) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004311 241.0
HKD1_k127_1468542_6 Nitrile hydratase beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000001154 215.0
HKD1_k127_1468542_7 - - - - 0.0000000000000000000000566 101.0
HKD1_k127_1490709_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 561.0
HKD1_k127_1490709_1 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 471.0
HKD1_k127_1490709_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 460.0
HKD1_k127_1490709_3 Amidohydrolase K10220 - 4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 447.0
HKD1_k127_150373_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 2.285e-249 775.0
HKD1_k127_150373_1 May be involved in recombinational repair of damaged DNA K03631 - - 3.736e-243 763.0
HKD1_k127_150373_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 3.623e-236 743.0
HKD1_k127_150373_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 552.0
HKD1_k127_150373_4 Belongs to the D-alanine--D-alanine ligase family K00075,K01921 - 1.3.1.98,6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 470.0
HKD1_k127_150373_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 441.0
HKD1_k127_150373_6 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 427.0
HKD1_k127_150373_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 413.0
HKD1_k127_150373_8 Essential cell division protein K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004674 268.0
HKD1_k127_150373_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000004375 58.0
HKD1_k127_150423_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 345.0
HKD1_k127_150423_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 322.0
HKD1_k127_150423_2 Bacterial signalling protein N terminal repeat - - - 0.0000000000009464 71.0
HKD1_k127_1521518_0 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 464.0
HKD1_k127_1521518_1 Serine aminopeptidase, S33 K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 435.0
HKD1_k127_1521518_2 Inositol monophosphatase family K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 391.0
HKD1_k127_1521518_3 response regulator K13589 - - 0.0000000000000000000000000000000000000000000000000000000000000363 215.0
HKD1_k127_1521518_4 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.00001587 49.0
HKD1_k127_1530704_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.437e-234 733.0
HKD1_k127_1530704_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 463.0
HKD1_k127_1530704_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 453.0
HKD1_k127_1544462_0 His Kinase A (phosphoacceptor) domain - - - 2.945e-214 687.0
HKD1_k127_1544462_1 Pantothenic acid kinase K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 510.0
HKD1_k127_1544462_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 460.0
HKD1_k127_1544462_3 Acetyltransferase (GNAT) domain K22310 - 2.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 403.0
HKD1_k127_1544462_4 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 387.0
HKD1_k127_1544462_5 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 307.0
HKD1_k127_1544462_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003483 248.0
HKD1_k127_1544462_7 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.000000000000000000000000000001715 124.0
HKD1_k127_1588311_0 Acyl-CoA dehydrogenase, middle domain K00253 - 1.3.8.4 1.882e-212 662.0
HKD1_k127_1588311_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 361.0
HKD1_k127_1588311_2 Iron permease FTR1 family K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 316.0
HKD1_k127_1588311_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 300.0
HKD1_k127_1588311_4 Cupredoxin-like domain - - - 0.000000000000000000000000000009146 121.0
HKD1_k127_1588311_5 transcriptional regulator, XRE family K07726 - - 0.0000000000000000000000001505 109.0
HKD1_k127_1588311_6 Lysozyme inhibitor LprI - - - 0.000000000000000000003074 100.0
HKD1_k127_1590577_0 Dehydratase family K22186 - 4.2.1.82 1.139e-316 976.0
HKD1_k127_1590577_1 Extracellular solute-binding protein K02027 - - 1.03e-217 682.0
HKD1_k127_1590577_10 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000000000000000000000004627 210.0
HKD1_k127_1590577_11 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000003117 199.0
HKD1_k127_1590577_12 Domain of unknown function (DUF3597) - - - 0.0000000000000000000000000000000000000000001208 162.0
HKD1_k127_1590577_13 Transglycosylase associated protein - - - 0.000000000000000000000000000000000000000004849 155.0
HKD1_k127_1590577_14 Recombinase zinc beta ribbon domain - - - 0.000000006204 69.0
HKD1_k127_1590577_2 Belongs to the ABC transporter superfamily K02010,K10112 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 574.0
HKD1_k127_1590577_3 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 549.0
HKD1_k127_1590577_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 514.0
HKD1_k127_1590577_5 Domain of unknown function (DUF4118) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 367.0
HKD1_k127_1590577_6 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 353.0
HKD1_k127_1590577_7 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 347.0
HKD1_k127_1590577_8 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001447 282.0
HKD1_k127_1590577_9 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007493 244.0
HKD1_k127_1598370_0 TIGRFAM Outer membrane protein - - - 2.008e-316 981.0
HKD1_k127_1598370_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06148 - - 4.752e-236 743.0
HKD1_k127_1598370_10 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000009854 100.0
HKD1_k127_1598370_11 PQ loop repeat K15383 - - 0.00000000000000000000001871 113.0
HKD1_k127_1598370_12 amine oxidase K00274 - 1.4.3.4 0.00000000000009223 78.0
HKD1_k127_1598370_13 - - - - 0.000000000002903 73.0
HKD1_k127_1598370_14 - - - - 0.00000008862 59.0
HKD1_k127_1598370_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02022 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 523.0
HKD1_k127_1598370_3 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 421.0
HKD1_k127_1598370_4 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 374.0
HKD1_k127_1598370_5 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 367.0
HKD1_k127_1598370_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 353.0
HKD1_k127_1598370_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 338.0
HKD1_k127_1598370_8 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000001901 210.0
HKD1_k127_1598370_9 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000007217 156.0
HKD1_k127_1607137_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 441.0
HKD1_k127_1607137_1 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000115 211.0
HKD1_k127_1607137_2 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000001296 98.0
HKD1_k127_1607137_3 - - - - 0.0000000000000000000004974 100.0
HKD1_k127_1607137_4 - - - - 0.00000000000001215 78.0
HKD1_k127_1617336_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 501.0
HKD1_k127_1617336_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 377.0
HKD1_k127_1617479_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1219.0
HKD1_k127_1617479_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 1.535e-231 730.0
HKD1_k127_1617479_2 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 389.0
HKD1_k127_1617479_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000005184 259.0
HKD1_k127_1617479_4 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000001442 114.0
HKD1_k127_1617479_5 - - - - 0.00000000000000000000000001731 111.0
HKD1_k127_1617479_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000166 76.0
HKD1_k127_16320_0 Penicillin-binding Protein K03587 - 3.4.16.4 1.3e-261 814.0
HKD1_k127_16320_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 7.899e-197 627.0
HKD1_k127_16320_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01928,K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 602.0
HKD1_k127_16320_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 580.0
HKD1_k127_16320_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 472.0
HKD1_k127_1635696_0 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 441.0
HKD1_k127_1635696_1 PFAM Glutathione S-transferase domain K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 375.0
HKD1_k127_1635696_2 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000001352 92.0
HKD1_k127_1635696_3 - - - - 0.0000000000001786 78.0
HKD1_k127_1635696_4 Tetratricopeptide repeat - - - 0.00000000006159 62.0
HKD1_k127_165522_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.874e-285 885.0
HKD1_k127_165522_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 5.068e-216 679.0
HKD1_k127_165522_10 NMT1-like family K02051,K15553 - - 0.000000000000000000000000000000000001471 151.0
HKD1_k127_165522_11 Histidine triad (Hit) protein - - - 0.00000000000000000000000000000000001674 140.0
HKD1_k127_165522_12 Isochorismatase family - - - 0.00000000000000000000000000000002457 129.0
HKD1_k127_165522_13 Isochorismatase family - - - 0.0000000000001105 78.0
HKD1_k127_165522_14 thioesterase K01075 - 3.1.2.23 0.00001153 49.0
HKD1_k127_165522_2 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 595.0
HKD1_k127_165522_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046,K00065 - 1.1.1.127,1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 355.0
HKD1_k127_165522_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 350.0
HKD1_k127_165522_5 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 320.0
HKD1_k127_165522_6 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007856 288.0
HKD1_k127_165522_7 Cyclic nucleotide-monophosphate binding domain K21564 - - 0.000000000000000000000000000000000000000000000000000000000000000001352 234.0
HKD1_k127_165522_8 - - - - 0.000000000000000000000000000000000000000000000000000002238 195.0
HKD1_k127_165522_9 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000000000000000004545 207.0
HKD1_k127_1663655_0 MMPL family K07003 - - 4.461e-281 879.0
HKD1_k127_1664037_0 Thiamine pyrophosphate enzyme, central domain K03852 - 2.3.3.15 0.0 1088.0
HKD1_k127_1664037_1 Aldehyde dehydrogenase family K13922,K15515 - 1.2.1.81,1.2.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 417.0
HKD1_k127_1740656_0 MoeA C-terminal region (domain IV) K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 609.0
HKD1_k127_1740656_1 Amidohydrolase family K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 452.0
HKD1_k127_1740656_10 Glycine zipper - - - 0.00000000001151 68.0
HKD1_k127_1740656_11 TPR repeat - - - 0.00000006263 54.0
HKD1_k127_1740656_2 amine oxidase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 447.0
HKD1_k127_1740656_3 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 401.0
HKD1_k127_1740656_4 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 387.0
HKD1_k127_1740656_5 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 367.0
HKD1_k127_1740656_6 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 338.0
HKD1_k127_1740656_7 Nitroreductase family K19286 - 1.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 327.0
HKD1_k127_1740656_8 MoeA N-terminal region (domain I and II) - - - 0.000000000000000000000000000000000000000000000000000000001279 214.0
HKD1_k127_1740656_9 sulfur carrier activity K04085 - - 0.000000000000000000001114 96.0
HKD1_k127_1787866_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 9.33e-237 736.0
HKD1_k127_1787866_1 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 362.0
HKD1_k127_1787866_2 Imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 332.0
HKD1_k127_1787866_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 315.0
HKD1_k127_1787866_4 Smr domain - - - 0.000000000000000000000000000000000000000000000004024 179.0
HKD1_k127_1787866_5 Protein of unknown function (DUF2628) - - - 0.000000000000000000000000000000000000001187 153.0
HKD1_k127_1787866_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000001398 71.0
HKD1_k127_1826541_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 447.0
HKD1_k127_1826541_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000879 271.0
HKD1_k127_1826541_2 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009863 267.0
HKD1_k127_1826541_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000008463 258.0
HKD1_k127_1826541_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000004546 195.0
HKD1_k127_1930192_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.11e-258 809.0
HKD1_k127_1930192_1 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 327.0
HKD1_k127_1930192_2 Invasion associated locus B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001123 258.0
HKD1_k127_197167_0 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005838 602.0
HKD1_k127_197167_1 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 473.0
HKD1_k127_197167_2 Amidohydrolase - - - 0.000000000000000002042 84.0
HKD1_k127_2013359_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1054.0
HKD1_k127_2013359_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000006862 183.0
HKD1_k127_2013359_2 - - - - 0.000000000000000000000000000008536 127.0
HKD1_k127_2020192_0 LssY C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 405.0
HKD1_k127_2020192_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000003161 184.0
HKD1_k127_2020192_2 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000000000000000000000001995 162.0
HKD1_k127_2020192_3 - - - - 0.0000000000001337 78.0
HKD1_k127_2030048_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 8.218e-222 697.0
HKD1_k127_2030048_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 529.0
HKD1_k127_2030048_2 AsmA-like C-terminal region K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 445.0
HKD1_k127_2030048_3 Part of the ABC transporter complex potABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 428.0
HKD1_k127_2030048_4 Binding-protein-dependent transport system inner membrane component K11075 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 429.0
HKD1_k127_2030048_5 Binding-protein-dependent transport system inner membrane component K11074 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 392.0
HKD1_k127_2030048_6 - - - - 0.000000000000000000003973 95.0
HKD1_k127_2031910_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0 1210.0
HKD1_k127_2031910_1 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 4.002e-254 800.0
HKD1_k127_2031910_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 297.0
HKD1_k127_2032378_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1353.0
HKD1_k127_2032378_1 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 605.0
HKD1_k127_2032378_10 Protein of unknown function (DUF721) - - - 0.00000000000000000000000000000000000000000000005164 182.0
HKD1_k127_2032378_11 - - - - 0.000000000000000000002938 102.0
HKD1_k127_2032378_12 - - - - 0.00000000002973 67.0
HKD1_k127_2032378_13 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.0008741 42.0
HKD1_k127_2032378_2 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 454.0
HKD1_k127_2032378_3 FES K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 454.0
HKD1_k127_2032378_4 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 375.0
HKD1_k127_2032378_5 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004105 280.0
HKD1_k127_2032378_6 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000001373 235.0
HKD1_k127_2032378_7 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000000000000000000001187 215.0
HKD1_k127_2032378_8 Belongs to the CinA family - - - 0.00000000000000000000000000000000000000000000000000000005695 201.0
HKD1_k127_2032378_9 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000001262 179.0
HKD1_k127_2032871_0 TIGRFAM cytochrome c oxidase accessory protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 6.025e-222 699.0
HKD1_k127_2032871_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4 2.103e-203 644.0
HKD1_k127_2032871_2 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003069 278.0
HKD1_k127_2032871_3 FixH - - - 0.0000000000000000000000000000000000000002755 155.0
HKD1_k127_2033777_0 PEP-utilising enzyme, N-terminal K08484 - 2.7.3.9 0.0 1179.0
HKD1_k127_2033777_1 Belongs to the thiolase family K00626 - 2.3.1.9 1.875e-215 672.0
HKD1_k127_2033777_10 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 359.0
HKD1_k127_2033777_11 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 353.0
HKD1_k127_2033777_12 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003106 283.0
HKD1_k127_2033777_13 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000001667 272.0
HKD1_k127_2033777_14 Polyhydroxyalkanoate synthesis repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002815 267.0
HKD1_k127_2033777_15 Class II aldolase K18613 GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0030145,GO:0034641,GO:0042365,GO:0042737,GO:0042816,GO:0042820,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047431,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 4.1.1.51 0.00000000000000000000000000000000000000000000000000000000000000003812 232.0
HKD1_k127_2033777_16 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000000000000000000000000005633 210.0
HKD1_k127_2033777_17 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000000000000000000000000006685 203.0
HKD1_k127_2033777_18 Protein of unknown function (DUF1345) - - - 0.00000000000000000000000000000000000000000000000000001265 196.0
HKD1_k127_2033777_19 Domain of unknown function (DUF4167) - - - 0.00000000000000000000000000000000000000000000000008308 188.0
HKD1_k127_2033777_2 Sodium/hydrogen exchanger family K03316 - - 2.528e-214 685.0
HKD1_k127_2033777_20 - - - - 0.00000000000000000000000000000000000000009551 154.0
HKD1_k127_2033777_21 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000003791 117.0
HKD1_k127_2033777_22 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000004715 78.0
HKD1_k127_2033777_23 Antibiotic biosynthesis monooxygenase - - - 0.0000000000002219 75.0
HKD1_k127_2033777_24 EamA-like transporter family - - - 0.0000000003991 60.0
HKD1_k127_2033777_3 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 1.221e-204 659.0
HKD1_k127_2033777_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 559.0
HKD1_k127_2033777_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 516.0
HKD1_k127_2033777_6 KR domain K00023 - 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 404.0
HKD1_k127_2033777_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 394.0
HKD1_k127_2033777_8 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 372.0
HKD1_k127_2033777_9 Belongs to the FPP GGPP synthase family K00795 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 367.0
HKD1_k127_2036418_0 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 303.0
HKD1_k127_2036418_1 - - - - 0.0000000000000597 79.0
HKD1_k127_2036418_2 OmpA-like transmembrane domain K16079 - - 0.00000003371 58.0
HKD1_k127_2036418_3 Ribbon-helix-helix domain - - - 0.000004425 49.0
HKD1_k127_2042721_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1892.0
HKD1_k127_2042721_1 Domain of unknown function (DUF4403) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 540.0
HKD1_k127_2042721_10 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005033 284.0
HKD1_k127_2042721_11 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000706 270.0
HKD1_k127_2042721_12 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002557 248.0
HKD1_k127_2042721_13 - - - - 0.0000000000000000000000000000000001897 142.0
HKD1_k127_2042721_14 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000006176 130.0
HKD1_k127_2042721_15 - - - - 0.00000000000000000000000001252 115.0
HKD1_k127_2042721_16 - - - - 0.00000000000000000000000166 108.0
HKD1_k127_2042721_2 arsR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 480.0
HKD1_k127_2042721_3 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 462.0
HKD1_k127_2042721_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K06125 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 428.0
HKD1_k127_2042721_5 homocysteine K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 409.0
HKD1_k127_2042721_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 398.0
HKD1_k127_2042721_7 Extensin-like protein C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 361.0
HKD1_k127_2042721_8 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 301.0
HKD1_k127_2042721_9 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 300.0
HKD1_k127_2043134_0 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 586.0
HKD1_k127_2043134_1 cation transmembrane transporter activity K07300 GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035725,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 464.0
HKD1_k127_2043134_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 409.0
HKD1_k127_2043134_3 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005455 259.0
HKD1_k127_2043134_4 oxidation-reduction process - - - 0.0000000000000000005627 95.0
HKD1_k127_206023_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.095e-228 721.0
HKD1_k127_206023_1 [2Fe-2S] binding domain - - - 0.000000000000000002797 84.0
HKD1_k127_2062088_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 425.0
HKD1_k127_2062088_1 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases K00101,K15054 - 1.1.2.3,1.1.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 367.0
HKD1_k127_2062088_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 353.0
HKD1_k127_2062088_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006034 246.0
HKD1_k127_2070400_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.554e-253 785.0
HKD1_k127_2070400_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003104 281.0
HKD1_k127_2070400_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000271 60.0
HKD1_k127_2073076_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 594.0
HKD1_k127_2073076_1 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 376.0
HKD1_k127_2073076_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000003199 117.0
HKD1_k127_2081472_0 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 1.277e-204 639.0
HKD1_k127_2081472_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 343.0
HKD1_k127_2081472_2 PAN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001295 226.0
HKD1_k127_2087649_0 AAA C-terminal domain K07478 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 8.875e-241 749.0
HKD1_k127_2087649_1 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 521.0
HKD1_k127_2087649_2 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.00000000000000007795 81.0
HKD1_k127_2087649_3 COG2116 Formate nitrite family of transporters K21990 - - 0.00000002403 55.0
HKD1_k127_2093802_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.854e-315 976.0
HKD1_k127_2093802_1 Hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 1.906e-304 956.0
HKD1_k127_2093802_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 463.0
HKD1_k127_2093802_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.00000000000000000000000000000000000000000000000000000001889 205.0
HKD1_k127_2093802_4 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000005951 175.0
HKD1_k127_2093802_5 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000000000000651 171.0
HKD1_k127_2093802_6 - - - - 0.000000000000000000000000000000000003382 145.0
HKD1_k127_2093802_7 Domain of unknown function (DUF3463) - - - 0.0000000000000000000001397 97.0
HKD1_k127_2093802_8 - - - - 0.0000000001492 66.0
HKD1_k127_2096740_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.996e-226 708.0
HKD1_k127_2096740_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 3.007e-199 629.0
HKD1_k127_2096740_2 nucleoside-triphosphate diphosphatase activity K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 359.0
HKD1_k127_2096740_3 Belongs to the UPF0262 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008886 271.0
HKD1_k127_2096740_4 Low molecular weight phosphotyrosine protein phosphatase K01104,K03741 - 1.20.4.1,3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000003357 220.0
HKD1_k127_2096740_5 Protein of unknown function (DUF2948) - - - 0.0000000000000000000000000000000000000000000000000129 184.0
HKD1_k127_2096740_6 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.000000000000000000000000000000000000000000004238 175.0
HKD1_k127_2096740_7 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.00000000000000000000007405 99.0
HKD1_k127_2096740_8 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000000139 90.0
HKD1_k127_2097207_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 7.067e-296 914.0
HKD1_k127_2097207_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.709e-244 758.0
HKD1_k127_2097207_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 411.0
HKD1_k127_2097207_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003175 261.0
HKD1_k127_2097207_4 EamA-like transporter family - - - 0.0000000000000001644 84.0
HKD1_k127_211565_0 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 588.0
HKD1_k127_211565_1 inositol 2-dehydrogenase activity K18106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 563.0
HKD1_k127_211565_2 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 546.0
HKD1_k127_211565_3 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 374.0
HKD1_k127_211565_4 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 371.0
HKD1_k127_211565_5 Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 366.0
HKD1_k127_211565_6 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 318.0
HKD1_k127_211565_7 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000116 214.0
HKD1_k127_211565_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000003376 193.0
HKD1_k127_2116601_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 480.0
HKD1_k127_2116601_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 390.0
HKD1_k127_2116601_2 carbon monoxide dehydrogenase K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 287.0
HKD1_k127_2139252_0 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 464.0
HKD1_k127_2139252_1 Putative transmembrane protein (Alph_Pro_TM) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007785 317.0
HKD1_k127_2139252_2 Sel1-like repeats. K07126,K13582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000432 287.0
HKD1_k127_2139252_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000003226 162.0
HKD1_k127_2155320_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 8.493e-219 679.0
HKD1_k127_2155320_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 285.0
HKD1_k127_2155320_2 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.00000000000000000000000000000000000000000000000000003367 191.0
HKD1_k127_2155320_3 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.00000001144 62.0
HKD1_k127_2155320_4 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.00002238 55.0
HKD1_k127_21698_0 Sulfatase K01130 - 3.1.6.1 0.0 1568.0
HKD1_k127_21698_1 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 409.0
HKD1_k127_21698_2 Domain of unknown function (DUF4399) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001036 241.0
HKD1_k127_2202837_0 AMP-binding enzyme K12508 - 6.2.1.34 2.748e-223 708.0
HKD1_k127_2202837_1 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 379.0
HKD1_k127_2202837_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 347.0
HKD1_k127_2202837_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002464 241.0
HKD1_k127_2202837_4 Protein of unknown function (DUF3237) - - - 0.00000000000000000000000000000000000000000002354 168.0
HKD1_k127_2213784_0 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 516.0
HKD1_k127_2213784_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 400.0
HKD1_k127_2213784_10 transferase activity, transferring glycosyl groups - - - 0.000000000000000000006419 102.0
HKD1_k127_2213784_11 PFAM BA14K family protein - - - 0.0000009965 56.0
HKD1_k127_2213784_2 MASE1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 382.0
HKD1_k127_2213784_3 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000004963 223.0
HKD1_k127_2213784_4 BON domain - - - 0.00000000000000000000000000000000000000000000000000000001144 206.0
HKD1_k127_2213784_5 Ion channel - - - 0.00000000000000000000000000000000000000000002007 173.0
HKD1_k127_2213784_6 dTDP-4-dehydrorhamnose 3,5-epimerase activity K00067,K01710,K01790 - 1.1.1.133,4.2.1.46,5.1.3.13 0.0000000000000000000000000000000000000000006594 162.0
HKD1_k127_2213784_7 LTXXQ motif family protein K07803 - - 0.0000000000000000000000000000000000000897 151.0
HKD1_k127_2213784_8 Trypsin-like serine protease K04775 - - 0.00000000000000000000000000001582 129.0
HKD1_k127_2213784_9 Glycosyl transferase, family 2 - - - 0.0000000000000000000000009532 105.0
HKD1_k127_2214343_0 transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 552.0
HKD1_k127_2214707_0 TIGRFAM phosphonate ABC transporter, inner membrane subunit K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 386.0
HKD1_k127_2214707_1 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 367.0
HKD1_k127_2214707_2 COG3639 ABC-type phosphate phosphonate transport system, permease component - - - 0.000000000000000000000000000000000000000000000001533 175.0
HKD1_k127_2214707_3 Flagellar biosynthesis protein, FliO - - - 0.000000000001222 76.0
HKD1_k127_2235640_0 PHB de-polymerase C-terminus K05973 - 3.1.1.75 3.039e-207 657.0
HKD1_k127_2235640_1 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 611.0
HKD1_k127_2235640_10 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000008359 196.0
HKD1_k127_2235640_11 - - - - 0.0000000000000000000000000000000000000000000000000004581 194.0
HKD1_k127_2235640_12 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000000000000001034 183.0
HKD1_k127_2235640_13 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000007932 185.0
HKD1_k127_2235640_14 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000265 145.0
HKD1_k127_2235640_15 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000248 156.0
HKD1_k127_2235640_16 Belongs to the bacterial histone-like protein family K03530 - - 0.000000000000000000000000000000006662 130.0
HKD1_k127_2235640_17 Lytic transglycolase K03642 - - 0.000000000000000000000000001374 115.0
HKD1_k127_2235640_18 - - - - 0.000000000000003714 80.0
HKD1_k127_2235640_2 His Kinase A (phosphoacceptor) domain K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 545.0
HKD1_k127_2235640_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 514.0
HKD1_k127_2235640_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 451.0
HKD1_k127_2235640_5 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 417.0
HKD1_k127_2235640_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 357.0
HKD1_k127_2235640_7 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 307.0
HKD1_k127_2235640_8 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 287.0
HKD1_k127_2235640_9 DNA repair protein MmcB-like - - - 0.00000000000000000000000000000000000000000000000000000000002989 219.0
HKD1_k127_2243913_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008686 265.0
HKD1_k127_2243913_1 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003361 263.0
HKD1_k127_2243913_2 Protein of unknown function (DUF2794) - - - 0.000000000000000000000000000000000000000001189 158.0
HKD1_k127_2246608_0 FAD dependent oxidoreductase K04755,K09471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 461.0
HKD1_k127_2246608_1 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000001059 212.0
HKD1_k127_2246608_2 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000000000000000000000000005491 194.0
HKD1_k127_2253111_0 enoyl-CoA hydratase isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 7.09e-321 995.0
HKD1_k127_2253111_1 Protein of unknown function (DUF861) - - - 0.000000000000000000000000000000000000000000000000000000000000004212 220.0
HKD1_k127_2253111_2 Belongs to the thiolase family K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0033554,GO:0033812,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0071944,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 2.3.1.9 0.000000000000000000000000000000000000000004611 154.0
HKD1_k127_2257648_0 CHASE2 - - - 1.94e-261 829.0
HKD1_k127_2257648_1 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 489.0
HKD1_k127_2257648_10 Pfam:Pyridox_oxidase K07006 - - 0.000003768 55.0
HKD1_k127_2257648_2 Protein of unknown function (DUF1214) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 490.0
HKD1_k127_2257648_3 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 431.0
HKD1_k127_2257648_4 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000001203 228.0
HKD1_k127_2257648_5 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000001861 176.0
HKD1_k127_2257648_6 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000000000000000000000373 128.0
HKD1_k127_2257648_7 - - - - 0.00000000000000000000000000008536 119.0
HKD1_k127_2257648_8 - - - - 0.0000000000000000001386 97.0
HKD1_k127_2257648_9 - - - - 0.000000002744 61.0
HKD1_k127_225956_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K15022 - 1.17.1.10 1.112e-211 662.0
HKD1_k127_225956_1 ATP12 chaperone protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 287.0
HKD1_k127_225956_2 Belongs to the Dps family K04047 - - 0.00000000904 56.0
HKD1_k127_2260856_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 415.0
HKD1_k127_2260856_1 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 312.0
HKD1_k127_2260856_2 helicase superfamily c-terminal domain K17675 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000009248 265.0
HKD1_k127_2260856_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000000000004935 220.0
HKD1_k127_2260856_4 S4 domain K04762 - - 0.0000000000000000000000000004239 117.0
HKD1_k127_2260856_5 Peptidase family M48 - - - 0.0000000002899 61.0
HKD1_k127_2274085_0 membrane - - - 0.0 1023.0
HKD1_k127_2274085_1 Aerotolerance regulator N-terminal - - - 5.422e-251 787.0
HKD1_k127_2274085_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 490.0
HKD1_k127_2274085_3 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 462.0
HKD1_k127_2274085_4 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 310.0
HKD1_k127_2274085_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 305.0
HKD1_k127_2274085_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005351 258.0
HKD1_k127_2274085_7 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000002535 219.0
HKD1_k127_2274085_8 - - - - 0.0000000000000000000000000000000000000000000000000006659 190.0
HKD1_k127_2274085_9 Isocitrate/isopropylmalate dehydrogenase K00052 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.85 0.00000000000002438 74.0
HKD1_k127_2275706_0 Ftsk_gamma K03466 - - 4.506e-293 913.0
HKD1_k127_2292187_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 3.141e-269 837.0
HKD1_k127_2292187_1 COG2873 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 7.55e-230 720.0
HKD1_k127_2292187_10 COG5281, Phage-related minor tail protein - - - 0.0000000003413 61.0
HKD1_k127_2292187_11 transposase and inactivated derivatives, IS30 family - - - 0.00005664 47.0
HKD1_k127_2292187_2 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 4.063e-195 613.0
HKD1_k127_2292187_3 Phage tail tube protein - - - 0.0000000000000000000000000000000000000000000000000000000000001526 217.0
HKD1_k127_2292187_4 Phage tail tube protein, GTA-gp10 - - - 0.00000000000000000000000000000000000000000000000000000000003265 210.0
HKD1_k127_2292187_5 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000001605 199.0
HKD1_k127_2292187_6 COG5281, Phage-related minor tail protein - - - 0.00000000000000000000000000000000004765 140.0
HKD1_k127_2292187_7 Pfam Transposase IS66 - - - 0.00000000000000000000000000000001613 131.0
HKD1_k127_2292187_8 Conserved hypothetical protein 2217 (DUF2460) - - - 0.00000000000000000000000002571 110.0
HKD1_k127_2292187_9 - - - - 0.000000000119 63.0
HKD1_k127_2306997_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1149.0
HKD1_k127_2306997_1 protein involved in response to NO K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 431.0
HKD1_k127_2306997_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 342.0
HKD1_k127_2306997_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001319 287.0
HKD1_k127_2306997_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001684 267.0
HKD1_k127_2306997_5 Major facilitator superfamily - - - 0.00000000000000000000000000000000042 135.0
HKD1_k127_2335621_0 Carboxyl transferase domain K01966 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 5.475e-249 781.0
HKD1_k127_2335621_1 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002566 247.0
HKD1_k127_2335621_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000395 149.0
HKD1_k127_2335621_3 Domain of unknown function (DUF4260) - - - 0.000000000000000000000000000000000004029 141.0
HKD1_k127_2338366_0 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 411.0
HKD1_k127_2338366_1 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 318.0
HKD1_k127_2338366_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000939 284.0
HKD1_k127_2338366_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000006856 123.0
HKD1_k127_2345610_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 366.0
HKD1_k127_2345610_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 319.0
HKD1_k127_2345610_2 - - - - 0.00000000000000000000000000000000000000000000000000000002408 205.0
HKD1_k127_2345610_3 - - - - 0.000000000000000000000000000000000000000000000000000004196 207.0
HKD1_k127_2345610_4 Cupin domain - - - 0.000000000000000000000000000000000000000000000000816 181.0
HKD1_k127_2345610_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000001768 166.0
HKD1_k127_2345610_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00410,K00412 - - 0.000000000000000000000000000009847 118.0
HKD1_k127_2345610_7 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000001558 118.0
HKD1_k127_2346526_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1191.0
HKD1_k127_2346526_1 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 475.0
HKD1_k127_2346526_10 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.0000000000000000000000000000000000000000000000000000008092 198.0
HKD1_k127_2346526_11 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000008399 180.0
HKD1_k127_2346526_2 LAO AO transport system K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 462.0
HKD1_k127_2346526_3 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 443.0
HKD1_k127_2346526_4 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 441.0
HKD1_k127_2346526_5 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 427.0
HKD1_k127_2346526_6 COG3839 ABC-type sugar transport systems, ATPase components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 408.0
HKD1_k127_2346526_7 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 391.0
HKD1_k127_2346526_8 Protein of unknown function (DUF3750) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 331.0
HKD1_k127_2346526_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009034 277.0
HKD1_k127_2370173_0 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 369.0
HKD1_k127_2370173_1 phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000007014 200.0
HKD1_k127_2370173_2 Lipid A Biosynthesis N-terminal domain - - - 0.000000000000000000000000000000000000000000001172 166.0
HKD1_k127_2370173_3 COG3547 Transposase and inactivated derivatives - - - 0.00000000002528 64.0
HKD1_k127_2387912_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1757.0
HKD1_k127_2387912_1 Sulfatase K01130 - 3.1.6.1 5.976e-318 977.0
HKD1_k127_2387912_10 helix_turn_helix ASNC type - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005869 255.0
HKD1_k127_2387912_11 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000148 257.0
HKD1_k127_2387912_12 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002711 248.0
HKD1_k127_2387912_13 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000000003272 224.0
HKD1_k127_2387912_14 protein containing double-stranded beta helix domain - - - 0.00000000000000000000000000000000000000000000000000000000002752 209.0
HKD1_k127_2387912_15 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000002765 213.0
HKD1_k127_2387912_16 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000000005848 151.0
HKD1_k127_2387912_17 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000002754 142.0
HKD1_k127_2387912_18 - K06039,K07092 - - 0.000000000000000000000000000000000001839 142.0
HKD1_k127_2387912_19 Yqey-like protein K09117 - - 0.0000000000000000000000000004825 115.0
HKD1_k127_2387912_2 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 9.879e-225 700.0
HKD1_k127_2387912_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 529.0
HKD1_k127_2387912_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 520.0
HKD1_k127_2387912_5 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 432.0
HKD1_k127_2387912_6 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 364.0
HKD1_k127_2387912_7 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 342.0
HKD1_k127_2387912_8 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 347.0
HKD1_k127_2387912_9 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003165 267.0
HKD1_k127_239529_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.782e-271 839.0
HKD1_k127_239529_1 tail specific protease K03797 - 3.4.21.102 9.04e-228 711.0
HKD1_k127_239529_2 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 355.0
HKD1_k127_239529_3 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002825 258.0
HKD1_k127_239529_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02113,K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000002204 176.0
HKD1_k127_2407724_0 Diguanylate cyclase K13245 - 3.1.4.52 0.0 1516.0
HKD1_k127_2407724_1 ABC transporter K06147 - - 2.964e-254 797.0
HKD1_k127_2407724_10 Uncharacterized ACR, COG1678 K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 340.0
HKD1_k127_2407724_11 Protein of unknown function (DUF1013) K09987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 327.0
HKD1_k127_2407724_12 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 321.0
HKD1_k127_2407724_13 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001832 260.0
HKD1_k127_2407724_14 Disulphide bond corrector protein DsbC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000455 250.0
HKD1_k127_2407724_15 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000003151 238.0
HKD1_k127_2407724_16 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000004858 230.0
HKD1_k127_2407724_17 Acetyltransferase (GNAT) domain K03827 - - 0.0000000000000000000000000000000000000000000000000000000000000003669 222.0
HKD1_k127_2407724_18 Protein of unknown function (DUF1465) K13592 - - 0.000000000000000000000000000000000000000000000000000001834 197.0
HKD1_k127_2407724_19 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000004494 164.0
HKD1_k127_2407724_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 602.0
HKD1_k127_2407724_20 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000000000000000001638 146.0
HKD1_k127_2407724_21 Protein of unknown function (DUF1192) - - - 0.00000000000000002815 83.0
HKD1_k127_2407724_22 Metallo-beta-lactamase superfamily - - - 0.0000000000000002256 81.0
HKD1_k127_2407724_23 - - - - 0.0001146 49.0
HKD1_k127_2407724_3 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 497.0
HKD1_k127_2407724_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 498.0
HKD1_k127_2407724_5 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 476.0
HKD1_k127_2407724_6 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 487.0
HKD1_k127_2407724_7 MotA TolQ ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 440.0
HKD1_k127_2407724_8 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 394.0
HKD1_k127_2407724_9 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 350.0
HKD1_k127_2412710_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 1.972e-273 850.0
HKD1_k127_2412710_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 5.976e-262 811.0
HKD1_k127_2412710_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 3.63e-209 658.0
HKD1_k127_2412710_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 325.0
HKD1_k127_2412710_4 Protein of unknown function (DUF2865) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 319.0
HKD1_k127_2412710_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001094 276.0
HKD1_k127_2412710_6 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001609 274.0
HKD1_k127_2412710_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000005938 144.0
HKD1_k127_2412710_8 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.000000000000000000000000003222 118.0
HKD1_k127_2412710_9 - - - - 0.0000000000000000007934 96.0
HKD1_k127_2442552_0 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 559.0
HKD1_k127_2442552_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 494.0
HKD1_k127_2442552_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.0000000000000000000000000000000000000000000001489 176.0
HKD1_k127_2442552_3 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000002228 179.0
HKD1_k127_2442552_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis - - - 0.0000000000000000000000003601 119.0
HKD1_k127_2442552_5 Resolvase - - - 0.00000001079 58.0
HKD1_k127_244424_0 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 556.0
HKD1_k127_244424_1 Peptidase M16 inactive domain K07263,K07623 - - 0.0000000000000000000000000000005136 130.0
HKD1_k127_246315_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 392.0
HKD1_k127_246315_1 ErfK YbiS YcfS YnhG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000295 283.0
HKD1_k127_246315_2 - - - - 0.0000000000000000000000000000000000000000000003937 170.0
HKD1_k127_246315_3 Uncharacterized protein conserved in bacteria (DUF2076) K09945 - - 0.00000000000000000000000000000000000005126 150.0
HKD1_k127_246315_4 Chemotaxis phosphatase, CheZ K03414 - - 0.0000000000000000000000000003379 122.0
HKD1_k127_2464995_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 3.936e-232 735.0
HKD1_k127_2464995_1 4,5-dihydroxyphthalate decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 458.0
HKD1_k127_2464995_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 390.0
HKD1_k127_2464995_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 377.0
HKD1_k127_2464995_4 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 306.0
HKD1_k127_2464995_5 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004665 276.0
HKD1_k127_2464995_6 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000001163 197.0
HKD1_k127_2464995_7 NMT1-like family K02051 - - 0.000001863 58.0
HKD1_k127_2466466_0 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 612.0
HKD1_k127_2466466_1 acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 437.0
HKD1_k127_2466466_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 388.0
HKD1_k127_2466466_3 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000003681 190.0
HKD1_k127_2466466_4 Protein of unknown function (DUF2927) - - - 0.00000000000000000000000000000000000001043 156.0
HKD1_k127_2466466_5 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000002281 73.0
HKD1_k127_2468948_0 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 419.0
HKD1_k127_2468948_1 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 287.0
HKD1_k127_2494000_0 carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 575.0
HKD1_k127_2494000_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 495.0
HKD1_k127_2494000_2 thiamine pyrophosphate protein TPP binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 485.0
HKD1_k127_2494000_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 366.0
HKD1_k127_2494000_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 300.0
HKD1_k127_2494000_5 PFAM Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 309.0
HKD1_k127_2494000_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000001963 201.0
HKD1_k127_2494000_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000007597 144.0
HKD1_k127_2495159_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1509.0
HKD1_k127_2495159_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 1.023e-311 975.0
HKD1_k127_2495159_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 503.0
HKD1_k127_2495159_3 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 305.0
HKD1_k127_2495159_4 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000000000000000002158 126.0
HKD1_k127_2506838_0 Belongs to the bacterial solute-binding protein 3 family K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 519.0
HKD1_k127_2506838_1 amino acid ABC transporter K09970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 523.0
HKD1_k127_2506838_2 Binding-protein-dependent transport system inner membrane component K09971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 489.0
HKD1_k127_2506838_3 ATPases associated with a variety of cellular activities K02028,K09972 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 426.0
HKD1_k127_2506838_4 cystathionine beta-lyase K01760 - 4.4.1.8 0.00000000000000000000001159 101.0
HKD1_k127_251810_0 Glycosyl transferase family 21 K00694,K01210 - 2.4.1.12,3.2.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 595.0
HKD1_k127_251810_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 587.0
HKD1_k127_251810_2 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 364.0
HKD1_k127_251810_3 - - - - 0.000000000000000000000000000000000000000000000133 172.0
HKD1_k127_251810_4 cytochrome c - - - 0.000000000000000001524 87.0
HKD1_k127_251810_5 - - - - 0.00002534 52.0
HKD1_k127_2520910_0 Belongs to the ClpA ClpB family K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1369.0
HKD1_k127_2520910_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 600.0
HKD1_k127_2520910_10 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 287.0
HKD1_k127_2520910_11 PFAM heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001086 273.0
HKD1_k127_2520910_12 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001514 267.0
HKD1_k127_2520910_13 response regulator K11443 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006571 238.0
HKD1_k127_2520910_14 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000000000000001759 240.0
HKD1_k127_2520910_15 AzlC protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003139 237.0
HKD1_k127_2520910_16 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000000000000000000000005178 218.0
HKD1_k127_2520910_17 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000000000000000008474 212.0
HKD1_k127_2520910_18 - K09004 - - 0.00000000000000000000000000000000000000000000000000976 184.0
HKD1_k127_2520910_19 Phasin protein - - - 0.000000000000000000000000000000000000000008411 157.0
HKD1_k127_2520910_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 551.0
HKD1_k127_2520910_20 TIR domain - - - 0.00000000000000000000000000000000000000006227 160.0
HKD1_k127_2520910_21 Branched-chain amino acid transport - - - 0.00000000000000000000000000003442 126.0
HKD1_k127_2520910_22 Protein of unknown function (DUF3572) - - - 0.00000000000000000000001392 102.0
HKD1_k127_2520910_23 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000003 87.0
HKD1_k127_2520910_24 - - - - 0.00000000000000009293 92.0
HKD1_k127_2520910_3 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 524.0
HKD1_k127_2520910_4 ATPase MipZ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 462.0
HKD1_k127_2520910_5 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 460.0
HKD1_k127_2520910_6 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 437.0
HKD1_k127_2520910_7 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 395.0
HKD1_k127_2520910_8 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 301.0
HKD1_k127_2520910_9 Domain of unknown function (DUF1849) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 293.0
HKD1_k127_2530719_0 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 522.0
HKD1_k127_2530719_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 441.0
HKD1_k127_2530719_2 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 425.0
HKD1_k127_2530719_3 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007322 276.0
HKD1_k127_25796_0 Threonine synthase N terminus K01733 GO:0003674,GO:0003824,GO:0004795,GO:0006082,GO:0006520,GO:0006566,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016311,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 7.972e-212 666.0
HKD1_k127_25796_1 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 554.0
HKD1_k127_25796_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000000006686 103.0
HKD1_k127_25796_2 cytochrome c oxidase subunit III K02276 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 511.0
HKD1_k127_25796_3 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 284.0
HKD1_k127_25796_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006881 267.0
HKD1_k127_25796_5 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001967 258.0
HKD1_k127_25796_6 SURF1 family K14998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001986 246.0
HKD1_k127_25796_7 Protein of unknown function (DUF983) - - - 0.00000000000000000000000000000000000000000000000001917 181.0
HKD1_k127_25796_8 subfamily IA, variant 3 - - - 0.000000000000000000000000000000000000000000000003493 182.0
HKD1_k127_25796_9 - - - - 0.000000000000000000000000000000000001815 150.0
HKD1_k127_2667923_0 Phosphopantetheine attachment site K00666 - - 0.0 1248.0
HKD1_k127_2667923_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.191e-254 797.0
HKD1_k127_2667923_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP - - - 3.196e-202 638.0
HKD1_k127_2667923_3 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 347.0
HKD1_k127_2667923_4 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 359.0
HKD1_k127_2667923_5 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 287.0
HKD1_k127_2667923_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000002458 181.0
HKD1_k127_2667923_7 phosphoribosyltransferase K07100 - - 0.000000000000000000000000007703 111.0
HKD1_k127_2669246_0 helicase superfamily c-terminal domain K17675 - 3.6.4.13 3.06e-322 995.0
HKD1_k127_2669246_1 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 293.0
HKD1_k127_2680818_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 544.0
HKD1_k127_2680818_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051,K15553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 325.0
HKD1_k127_2680818_2 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 292.0
HKD1_k127_2680818_3 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000000000000000000000000005347 188.0
HKD1_k127_2680818_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000000004976 144.0
HKD1_k127_2680818_5 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component K00380 - 1.8.1.2 0.0000000000000000000001714 97.0
HKD1_k127_2680818_6 HNH nucleases - - - 0.0007844 42.0
HKD1_k127_2686578_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 577.0
HKD1_k127_2686578_1 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007865 244.0
HKD1_k127_2686578_2 PTS IIA-like nitrogen-regulatory protein PtsN K02806 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044424,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 - 0.00000000000000000000000000000000000000000000000000000000000000001976 228.0
HKD1_k127_2686578_3 Protein of unknown function (DUF1150) - - - 0.0000000000000000000000000000000003296 133.0
HKD1_k127_2686578_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000004243 128.0
HKD1_k127_2698347_0 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 554.0
HKD1_k127_2698347_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 534.0
HKD1_k127_2698347_2 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 458.0
HKD1_k127_2698347_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001383 238.0
HKD1_k127_2698347_4 - - - - 0.00000000000000000000000000000000000000000000000000000001271 204.0
HKD1_k127_2698347_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000000000000002279 169.0
HKD1_k127_2698347_6 Ribosomal L27 protein K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000001152 143.0
HKD1_k127_276481_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07484 - - 2.971e-261 815.0
HKD1_k127_276481_1 IS66 Orf2 like protein K07484 - - 0.00000000000000000000000000000000000000000000000000000000000000005227 224.0
HKD1_k127_276481_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07483 - - 0.000000000000000000000000000000113 128.0
HKD1_k127_276481_3 - - - - 0.0000000000000000000001364 102.0
HKD1_k127_2841197_0 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 512.0
HKD1_k127_2841197_1 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 317.0
HKD1_k127_2841197_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000001876 195.0
HKD1_k127_2841197_3 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000001409 180.0
HKD1_k127_2878824_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 9.66e-240 746.0
HKD1_k127_2878824_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 528.0
HKD1_k127_2878824_10 Ubiquinol-cytochrome C chaperone K17662 - - 0.0000000000000000000000000000000000000000003965 165.0
HKD1_k127_2878824_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 503.0
HKD1_k127_2878824_3 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 477.0
HKD1_k127_2878824_4 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 306.0
HKD1_k127_2878824_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 291.0
HKD1_k127_2878824_6 SmpA / OmlA family - - - 0.00000000000000000000000000000000000000000000000000001432 192.0
HKD1_k127_2878824_7 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000000001076 185.0
HKD1_k127_2878824_8 MerR HTH family regulatory protein - - - 0.000000000000000000000000000000000000000000000000001463 190.0
HKD1_k127_2878824_9 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000003346 166.0
HKD1_k127_2945301_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 391.0
HKD1_k127_2945301_1 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 348.0
HKD1_k127_2945301_2 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001047 279.0
HKD1_k127_2945301_3 Putative vitamin uptake transporter K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007549 254.0
HKD1_k127_2945301_4 WD40 repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000145 257.0
HKD1_k127_2945301_5 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 235.0
HKD1_k127_2945301_6 PFAM regulatory protein ArsR - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000004422 143.0
HKD1_k127_2945301_7 Regulatory protein SoxS - - - 0.0000000000000000000000000000000006907 135.0
HKD1_k127_2945301_8 - - - - 0.0000000000000000000000000000175 127.0
HKD1_k127_299159_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 1.278e-229 722.0
HKD1_k127_299159_1 Stringent starvation protein B K09985 - - 0.000000000000000000000000000000000000000000000000000000002366 207.0
HKD1_k127_299159_2 AsmA-like C-terminal region K07289 - - 0.000000000000000000000000000000000000000000000002606 193.0
HKD1_k127_299159_3 Ribbon-helix-helix domain - - - 0.000000000000000000000000000001748 124.0
HKD1_k127_299159_5 Domain of unknown function (DUF4169) - - - 0.0001028 47.0
HKD1_k127_299159_6 - - - - 0.0003365 45.0
HKD1_k127_2992800_0 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 3.148e-203 647.0
HKD1_k127_2992800_1 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 593.0
HKD1_k127_2992800_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 564.0
HKD1_k127_2992800_3 Zinc-binding dehydrogenase K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 496.0
HKD1_k127_2992800_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 417.0
HKD1_k127_2992800_5 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 343.0
HKD1_k127_2992800_6 Rubrerythrin - - - 0.0000000000000000000000000000000004129 137.0
HKD1_k127_3013666_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000004774 178.0
HKD1_k127_3013666_1 - - - - 0.0000000000000000000000002831 112.0
HKD1_k127_3013666_2 - - - - 0.000000000000000000000001462 114.0
HKD1_k127_3013666_3 - - - - 0.000000000000000000005388 96.0
HKD1_k127_3013666_4 - - - - 0.000000000000002068 82.0
HKD1_k127_3013666_5 Protein of unknown function (DUF1236) - - - 0.0000003925 58.0
HKD1_k127_3013666_7 Protein of unknown function (DUF3072) - - - 0.0005787 45.0
HKD1_k127_301371_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 1.686e-261 827.0
HKD1_k127_301371_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 2.641e-252 787.0
HKD1_k127_301371_2 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 410.0
HKD1_k127_301371_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 352.0
HKD1_k127_301371_4 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001633 264.0
HKD1_k127_301371_5 protein possibly involved in utilization of glycolate and propanediol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009658 257.0
HKD1_k127_301371_6 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000000000000004102 216.0
HKD1_k127_301371_7 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000008068 176.0
HKD1_k127_301371_8 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000005687 133.0
HKD1_k127_302853_0 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 549.0
HKD1_k127_302853_1 Ferrochelatase K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 486.0
HKD1_k127_302853_2 branched-chain amino acid K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 339.0
HKD1_k127_3042253_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1761.0
HKD1_k127_3042253_1 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 336.0
HKD1_k127_3042253_2 4Fe-4S dicluster domain K00124 - - 0.000000000000000002036 84.0
HKD1_k127_3051029_0 Alcohol dehydrogenase GroES-like domain K00001,K14446 - 1.1.1.1,1.3.1.85 8.498e-250 777.0
HKD1_k127_3051029_1 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 493.0
HKD1_k127_3051029_2 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 496.0
HKD1_k127_3051029_3 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 490.0
HKD1_k127_3051029_4 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 336.0
HKD1_k127_3051029_5 Transglycosylase associated protein - - - 0.00000000000000000000000001936 110.0
HKD1_k127_3052495_0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 336.0
HKD1_k127_3052495_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007322 276.0
HKD1_k127_3052495_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000002071 225.0
HKD1_k127_3052495_3 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000107 207.0
HKD1_k127_3052495_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000007425 164.0
HKD1_k127_3052495_5 ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000001538 89.0
HKD1_k127_3052495_6 SecY translocase - - - 0.00000000001309 66.0
HKD1_k127_3085914_0 Histidine kinase - - - 1.429e-198 631.0
HKD1_k127_3085914_1 Cytochrome c-type biogenesis protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 564.0
HKD1_k127_3085914_2 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 426.0
HKD1_k127_3085914_3 Cytochrome c-type biogenesis protein K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 384.0
HKD1_k127_3085914_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 381.0
HKD1_k127_3085914_5 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002701 267.0
HKD1_k127_3085914_6 surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000001626 219.0
HKD1_k127_3085914_7 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000001283 212.0
HKD1_k127_3088930_0 ribosomal rna small subunit methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 407.0
HKD1_k127_3088930_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000004063 192.0
HKD1_k127_3088930_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000002964 147.0
HKD1_k127_3089234_0 MoeA C-terminal region (domain IV) K03750 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0042802,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 452.0
HKD1_k127_3089234_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000006717 250.0
HKD1_k127_3095971_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 362.0
HKD1_k127_3095971_1 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004392 277.0
HKD1_k127_3095971_2 Iron-containing redox enzyme - - - 0.000000000000000000000000000000000000000000000000000000000001621 218.0
HKD1_k127_3095971_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000001425 164.0
HKD1_k127_3095971_4 AraC-binding-like domain - - - 0.000000000000000000000000000000000002728 150.0
HKD1_k127_3095971_5 AraC-binding-like domain - - - 0.0000000000000000000000000002151 128.0
HKD1_k127_3095971_6 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0002145 49.0
HKD1_k127_3096551_0 MMPL family K03296 - - 9.683e-306 949.0
HKD1_k127_3096551_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 394.0
HKD1_k127_3096551_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0006436 46.0
HKD1_k127_3101699_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000001345 237.0
HKD1_k127_3101699_1 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000002168 197.0
HKD1_k127_3101699_2 Sulfate permease family - - - 0.000000000000000000000002314 104.0
HKD1_k127_3101699_3 - - - - 0.000000000000000001707 87.0
HKD1_k127_3102288_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.533e-307 951.0
HKD1_k127_3102288_1 Polysaccharide biosynthesis protein K13013 - - 1.553e-277 865.0
HKD1_k127_3102288_10 Amidohydrolase K10220 - 4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 403.0
HKD1_k127_3102288_11 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 405.0
HKD1_k127_3102288_12 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 387.0
HKD1_k127_3102288_13 metal-dependent hydrolase of the TIM-barrel fold K07045,K14333,K15063 - 4.1.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 367.0
HKD1_k127_3102288_14 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 341.0
HKD1_k127_3102288_15 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 342.0
HKD1_k127_3102288_16 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 315.0
HKD1_k127_3102288_17 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 316.0
HKD1_k127_3102288_18 Branched-chain amino acid transport K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000739 286.0
HKD1_k127_3102288_19 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001468 272.0
HKD1_k127_3102288_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K03336 - 3.7.1.22 4.26e-275 858.0
HKD1_k127_3102288_20 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000002822 269.0
HKD1_k127_3102288_21 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001505 258.0
HKD1_k127_3102288_22 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000003638 234.0
HKD1_k127_3102288_23 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000447 222.0
HKD1_k127_3102288_24 Thioesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000000000000000000000006826 186.0
HKD1_k127_3102288_25 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000192 168.0
HKD1_k127_3102288_26 Cupin domain - - - 0.0000000000000000000000001654 112.0
HKD1_k127_3102288_3 Alcohol dehydrogenase GroES-like domain - - - 4.724e-200 641.0
HKD1_k127_3102288_4 ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 597.0
HKD1_k127_3102288_5 Molybdopterin-binding domain of aldehyde dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 512.0
HKD1_k127_3102288_6 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 506.0
HKD1_k127_3102288_7 Major facilitator superfamily K03449 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 443.0
HKD1_k127_3102288_8 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 435.0
HKD1_k127_3102288_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 424.0
HKD1_k127_3115291_0 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 549.0
HKD1_k127_3115291_1 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 535.0
HKD1_k127_3115291_2 ABC-type Fe3 transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000005251 224.0
HKD1_k127_3131441_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.0 1313.0
HKD1_k127_3131441_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 601.0
HKD1_k127_3131441_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 469.0
HKD1_k127_3131441_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 465.0
HKD1_k127_3131441_4 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007715 367.0
HKD1_k127_3131441_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 338.0
HKD1_k127_3131441_6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006578 269.0
HKD1_k127_3137134_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 605.0
HKD1_k127_3137134_1 Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 588.0
HKD1_k127_3137134_2 FAD linked K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 460.0
HKD1_k127_3137134_3 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 323.0
HKD1_k127_3137134_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000001409 185.0
HKD1_k127_3137134_5 ABC transporter K02471 - - 0.0000000000000000000002973 97.0
HKD1_k127_3145716_0 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 377.0
HKD1_k127_3145716_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 311.0
HKD1_k127_3145716_2 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001234 282.0
HKD1_k127_3145716_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002029 260.0
HKD1_k127_3145716_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000002627 219.0
HKD1_k127_3145716_5 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000003219 206.0
HKD1_k127_3145716_6 Domain of unknown function (DUF1932) - - - 0.0000000000000000000000000534 110.0
HKD1_k127_3152306_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.278e-222 700.0
HKD1_k127_3152306_1 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 544.0
HKD1_k127_3152306_2 Sel1-like repeats. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 366.0
HKD1_k127_3152306_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001275 261.0
HKD1_k127_3152306_4 Protein of unknown function (DUF1036) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009824 244.0
HKD1_k127_3152306_5 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000001524 229.0
HKD1_k127_3152306_6 Methionine synthase - - - 0.000000000000000000000000002701 113.0
HKD1_k127_3152306_7 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000001868 78.0
HKD1_k127_3153350_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1404.0
HKD1_k127_3153350_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 356.0
HKD1_k127_3153350_2 4Fe-4S binding domain K18362 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 343.0
HKD1_k127_3153350_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000003599 183.0
HKD1_k127_3153350_4 Thioesterase - - - 0.000000000000000000000000000000000000000009607 157.0
HKD1_k127_3154522_0 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 566.0
HKD1_k127_3154522_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 424.0
HKD1_k127_3154522_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 285.0
HKD1_k127_3154522_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004827 254.0
HKD1_k127_3154522_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000005953 218.0
HKD1_k127_3154522_5 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000002294 237.0
HKD1_k127_3154522_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000002205 183.0
HKD1_k127_3154522_7 Response regulator receiver - - - 0.00000000000000000000000000000000000000006706 154.0
HKD1_k127_3154522_8 - - - - 0.0000001258 59.0
HKD1_k127_3154547_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 402.0
HKD1_k127_3154547_1 COG1985 Pyrimidine reductase, riboflavin biosynthesis K00082 - 1.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 303.0
HKD1_k127_3154547_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 298.0
HKD1_k127_3154547_3 DNA repair - - - 0.0000000000000000001076 100.0
HKD1_k127_3154547_4 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000008822 91.0
HKD1_k127_3158561_0 Tripartite ATP-independent periplasmic transporter, DctM component K11690 GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0044425 - 9.984e-229 714.0
HKD1_k127_3158561_1 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 299.0
HKD1_k127_3158561_2 LTXXQ motif family protein K07803 - - 0.00000000000000000000000000000000000007293 148.0
HKD1_k127_3158561_3 Bacterial extracellular solute-binding protein, family 7 K11688 - - 0.000000000000000004059 85.0
HKD1_k127_3164062_0 FAD binding domain K00480,K14974 - 1.14.13.1,1.14.13.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 604.0
HKD1_k127_3164062_1 salicylate hydroxylase K00480,K22270 - 1.14.13.1,1.14.13.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 480.0
HKD1_k127_3164062_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 344.0
HKD1_k127_3164062_3 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000000000000000000000000000000001951 148.0
HKD1_k127_3164062_4 Belongs to the 'phage' integrase family - - - 0.0000000000000000006072 94.0
HKD1_k127_3173684_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 1.203e-291 899.0
HKD1_k127_3173684_1 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 456.0
HKD1_k127_3173684_2 VWA domain containing CoxE-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 299.0
HKD1_k127_3180790_0 FAD linked oxidases, C-terminal domain - - - 0.0 1402.0
HKD1_k127_3180790_1 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 8.255e-203 646.0
HKD1_k127_3180790_10 branched-chain amino acid K01995,K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 313.0
HKD1_k127_3180790_11 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 302.0
HKD1_k127_3180790_12 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000009809 200.0
HKD1_k127_3180790_13 Transcriptional regulator K05799 - - 0.0000000000000000000000000000000000000000000162 171.0
HKD1_k127_3180790_14 Cobalamin-independent synthase, Catalytic domain K00549,K22363 - 2.1.1.14,4.4.1.23 0.0000000108 56.0
HKD1_k127_3180790_2 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 597.0
HKD1_k127_3180790_3 Cobalamin-independent synthase, Catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 566.0
HKD1_k127_3180790_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 479.0
HKD1_k127_3180790_5 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999,K11959 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 449.0
HKD1_k127_3180790_6 Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 425.0
HKD1_k127_3180790_7 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 407.0
HKD1_k127_3180790_8 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 379.0
HKD1_k127_3180790_9 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 384.0
HKD1_k127_3186925_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 585.0
HKD1_k127_3186925_1 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 431.0
HKD1_k127_3186925_2 Peptidase family S49 K04773,K04774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 368.0
HKD1_k127_3186925_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 364.0
HKD1_k127_3186925_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001744 252.0
HKD1_k127_3186925_5 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000003969 225.0
HKD1_k127_3186925_6 Methyltransferase small domain K15460 - 2.1.1.223 0.00000000000000000003317 92.0
HKD1_k127_3186925_7 Methyltransferase small domain K15460 - 2.1.1.223 0.000000000001191 69.0
HKD1_k127_3186925_8 - - - - 0.00000000006109 64.0
HKD1_k127_3196861_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1245.0
HKD1_k127_3196861_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 429.0
HKD1_k127_3196861_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 388.0
HKD1_k127_3196861_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 312.0
HKD1_k127_3196861_4 Redoxin K02199 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002705 274.0
HKD1_k127_3196861_5 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000001057 257.0
HKD1_k127_3196861_6 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000000001312 238.0
HKD1_k127_3196861_7 - - - - 0.000000000000000000000000000000000000000004939 160.0
HKD1_k127_3196861_8 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.000000006274 58.0
HKD1_k127_3196861_9 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000001165 58.0
HKD1_k127_3235460_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 373.0
HKD1_k127_3235460_1 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000005844 228.0
HKD1_k127_3235460_2 Phosphomethylpyrimidine kinase K00868 - 2.7.1.35 0.00000000000000000000000000000000000009247 156.0
HKD1_k127_3259333_0 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 521.0
HKD1_k127_3259333_1 Kelch repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 319.0
HKD1_k127_3259333_2 myo-inosose-2 dehydratase activity K00457,K06606 - 1.13.11.27,5.3.99.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 292.0
HKD1_k127_3259333_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000003671 172.0
HKD1_k127_3259333_4 HWE histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000007308 142.0
HKD1_k127_3259333_5 PFAM Sugar (and other) transporter K08368,K08369 - - 0.00000000000000000000000000006534 129.0
HKD1_k127_3261035_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 3.415e-237 736.0
HKD1_k127_3261035_1 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 562.0
HKD1_k127_3261035_2 Dehydrogenase E1 component K00161,K00166,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 541.0
HKD1_k127_3261035_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 496.0
HKD1_k127_3261035_4 COG3243 Poly(3-hydroxyalkanoate) synthetase K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 315.0
HKD1_k127_3261035_5 Phosphopantetheine attachment site - - - 0.000000000000000000000000000001641 124.0
HKD1_k127_3261035_6 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 0.000000000000000000000001136 103.0
HKD1_k127_3274785_0 Glutamate synthase K00265 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 0.0 1178.0
HKD1_k127_3274785_1 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.000000000000000000000000000000002696 130.0
HKD1_k127_3274785_2 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0007059 49.0
HKD1_k127_3280732_0 Epoxide hydrolase N terminus K21159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 530.0
HKD1_k127_3280732_1 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 489.0
HKD1_k127_3280732_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 457.0
HKD1_k127_3280732_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 331.0
HKD1_k127_3280732_4 Cytochrome P460 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007711 279.0
HKD1_k127_3280732_5 Cupin - - - 0.000000000000000000000000000000000000000000003433 166.0
HKD1_k127_3293278_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 416.0
HKD1_k127_3293278_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 288.0
HKD1_k127_3293278_2 Thioesterase K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000005325 226.0
HKD1_k127_3327741_0 PFAM amidohydrolase 2 K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004638 250.0
HKD1_k127_3327741_1 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000007884 235.0
HKD1_k127_3327741_2 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000002953 141.0
HKD1_k127_3329887_0 ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 475.0
HKD1_k127_3329887_1 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 463.0
HKD1_k127_3329887_2 transport, permease protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 420.0
HKD1_k127_3329887_3 Peptidase dimerisation domain K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 411.0
HKD1_k127_3329887_4 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 297.0
HKD1_k127_3329887_5 Dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.00000000000000000000000000000000000000000000000000000000000000000001144 243.0
HKD1_k127_3329887_6 Haem-degrading - - - 0.000000000000000000000000000000001666 140.0
HKD1_k127_3361233_0 NAD dependent epimerase/dehydratase family - - - 1.642e-202 633.0
HKD1_k127_3361233_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 317.0
HKD1_k127_3361233_2 - - - - 0.0000002421 59.0
HKD1_k127_3365832_0 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009281 496.0
HKD1_k127_3365832_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 453.0
HKD1_k127_3365832_2 Protein of unknown function (DUF4239) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001866 263.0
HKD1_k127_3365832_3 - - - - 0.00000000000000000000000000000000000000007411 156.0
HKD1_k127_337802_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 447.0
HKD1_k127_337802_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000872 319.0
HKD1_k127_337802_2 Extracellular liganD-binding receptor K01999 - - 0.0000004734 52.0
HKD1_k127_3384394_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0 1019.0
HKD1_k127_3384394_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 7.885e-249 777.0
HKD1_k127_3384394_10 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003773 255.0
HKD1_k127_3384394_11 N-terminal half of MaoC dehydratase K17865 GO:0003674,GO:0003824,GO:0003859,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0046487,GO:0071704 4.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000001904 246.0
HKD1_k127_3384394_12 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000004884 262.0
HKD1_k127_3384394_13 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001538 252.0
HKD1_k127_3384394_14 Phytoene squalene synthetase K02291,K18163 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000009202 237.0
HKD1_k127_3384394_15 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000001474 230.0
HKD1_k127_3384394_16 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000003153 163.0
HKD1_k127_3384394_17 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000000000000000001942 119.0
HKD1_k127_3384394_18 antibiotic catabolic process - - - 0.00000000000000000000000000003423 125.0
HKD1_k127_3384394_19 Preprotein translocase subunit K03210 - - 0.000000000000000000000000004065 111.0
HKD1_k127_3384394_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 4.15e-224 703.0
HKD1_k127_3384394_20 Amidohydrolase K22213 - 4.1.1.52 0.0000000000000166 76.0
HKD1_k127_3384394_22 Domain of unknown function (DUF1127) - - - 0.0000000002266 64.0
HKD1_k127_3384394_3 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 2.192e-216 678.0
HKD1_k127_3384394_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 4.108e-206 647.0
HKD1_k127_3384394_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 504.0
HKD1_k127_3384394_6 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 422.0
HKD1_k127_3384394_7 membrane-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 316.0
HKD1_k127_3384394_8 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 299.0
HKD1_k127_3384394_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000082 277.0
HKD1_k127_3420814_0 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000000000000000000003696 205.0
HKD1_k127_3420814_1 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000018 122.0
HKD1_k127_3420814_2 - - - - 0.0000000000000000000000001195 108.0
HKD1_k127_3427900_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 400.0
HKD1_k127_3427900_1 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 385.0
HKD1_k127_3427900_10 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001121 249.0
HKD1_k127_3427900_11 BON domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001327 238.0
HKD1_k127_3427900_12 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000002745 231.0
HKD1_k127_3427900_13 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000004071 227.0
HKD1_k127_3427900_14 Class II aldolase adducin family protein - - - 0.0000000000000000000000000000000000000000000000000000000001212 212.0
HKD1_k127_3427900_15 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.000000000000000000000000000000000000000000000005551 185.0
HKD1_k127_3427900_16 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000000000000002636 170.0
HKD1_k127_3427900_17 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000001172 82.0
HKD1_k127_3427900_18 COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.00000000000000002221 89.0
HKD1_k127_3427900_2 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 379.0
HKD1_k127_3427900_3 Domain of unknown function (DUF4118) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 377.0
HKD1_k127_3427900_4 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 367.0
HKD1_k127_3427900_5 IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 346.0
HKD1_k127_3427900_6 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 291.0
HKD1_k127_3427900_7 PFAM amidohydrolase 2 K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000252 289.0
HKD1_k127_3427900_8 Amidohydrolase K22213 - 4.1.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000003268 257.0
HKD1_k127_3427900_9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001778 247.0
HKD1_k127_3431427_0 Tetratricopeptide repeat - - - 1.115e-292 943.0
HKD1_k127_3431427_1 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 8.364e-210 658.0
HKD1_k127_3431427_10 Belongs to the flagella basal body rod proteins family K02391,K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 311.0
HKD1_k127_3431427_11 Chaperone for flagella basal body P-ring formation K02386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003126 273.0
HKD1_k127_3431427_12 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000002924 265.0
HKD1_k127_3431427_13 Putative zinc- or iron-chelating domain K09160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005263 246.0
HKD1_k127_3431427_14 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000001945 244.0
HKD1_k127_3431427_15 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000008113 232.0
HKD1_k127_3431427_16 PFAM MgtE intracellular - - - 0.000000000000000000000000000000000000000000000000000000000000005487 228.0
HKD1_k127_3431427_17 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000001416 224.0
HKD1_k127_3431427_18 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.000000000000000000000000000000000000000000000000000000000008779 212.0
HKD1_k127_3431427_19 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000000000000000000000000000000000004182 189.0
HKD1_k127_3431427_2 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 606.0
HKD1_k127_3431427_20 Class II flagellar assembly regulator - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000002134 142.0
HKD1_k127_3431427_21 organic phosphonate transport K02044 - - 0.0000000000000000000000000001875 118.0
HKD1_k127_3431427_22 Rod binding protein - - - 0.0000000000000000000000000007329 115.0
HKD1_k127_3431427_23 - - - - 0.000000000000000000000000001198 117.0
HKD1_k127_3431427_24 - - - - 0.000000000000000000000003234 112.0
HKD1_k127_3431427_25 - - - - 0.00006046 46.0
HKD1_k127_3431427_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 563.0
HKD1_k127_3431427_4 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 515.0
HKD1_k127_3431427_5 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 494.0
HKD1_k127_3431427_6 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 501.0
HKD1_k127_3431427_7 flagellar basal-body rod protein FlgG K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 398.0
HKD1_k127_3431427_8 3-beta hydroxysteroid dehydrogenase/isomerase family K18981 - 1.1.1.203 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 393.0
HKD1_k127_3431427_9 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 360.0
HKD1_k127_350925_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 2.717e-254 799.0
HKD1_k127_350925_1 Biotin carboxylase C-terminal domain K01965 GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 8.565e-232 722.0
HKD1_k127_350925_2 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 407.0
HKD1_k127_350925_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 340.0
HKD1_k127_350925_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000003379 207.0
HKD1_k127_350925_5 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000001011 159.0
HKD1_k127_350925_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000001928 94.0
HKD1_k127_3513484_0 Alpha-2-Macroglobulin K06894 - - 0.0 2250.0
HKD1_k127_3513484_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 1.472e-264 834.0
HKD1_k127_3513484_2 glycosyl transferase, family 39 - - - 1.077e-223 706.0
HKD1_k127_3513484_3 - - - - 0.00000000000000000000000000000000000000000001648 172.0
HKD1_k127_3513484_4 - - - - 0.000000000003896 71.0
HKD1_k127_3524201_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 505.0
HKD1_k127_3524201_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 493.0
HKD1_k127_3524201_2 Methionine synthase K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 468.0
HKD1_k127_3524201_3 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 464.0
HKD1_k127_3524201_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 384.0
HKD1_k127_3524201_5 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000001496 74.0
HKD1_k127_3531837_0 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 1.455e-225 704.0
HKD1_k127_3531837_1 Transcriptional regulatory protein, C terminal K02483,K13584 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 451.0
HKD1_k127_3531837_2 Flagellar FliJ protein - - - 0.0000000000000000000000000000000000000000000000000000005053 195.0
HKD1_k127_3531837_3 - - - - 0.000000000000000000000000000000000000000000003866 179.0
HKD1_k127_3531837_4 Helix-turn-helix domain - - - 0.000000000000000000000000000000002537 130.0
HKD1_k127_3531837_5 PFAM response regulator receiver K03413 - - 0.0000000000000002486 81.0
HKD1_k127_3531837_6 cheY-homologous receiver domain K03413 - - 0.0007066 46.0
HKD1_k127_3533056_0 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 487.0
HKD1_k127_3533056_1 Branched-chain amino acid ATP-binding cassette transporter K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 394.0
HKD1_k127_3533056_2 ATPases associated with a variety of cellular activities K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 380.0
HKD1_k127_3533056_3 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 357.0
HKD1_k127_3533056_4 - - - - 0.000000000000000000000000000002619 125.0
HKD1_k127_3552793_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 470.0
HKD1_k127_3552793_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 404.0
HKD1_k127_3552793_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 342.0
HKD1_k127_3552793_3 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 299.0
HKD1_k127_3552793_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005334 258.0
HKD1_k127_3567202_0 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 386.0
HKD1_k127_3567202_1 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 373.0
HKD1_k127_3567202_2 electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001471 263.0
HKD1_k127_3567202_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000004724 170.0
HKD1_k127_3567202_4 - - - - 0.0003497 47.0
HKD1_k127_3571821_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.188e-233 737.0
HKD1_k127_3571821_1 HIT domain - - - 0.0000000000000000000000000000000000000000000000000004816 188.0
HKD1_k127_3571821_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000004098 179.0
HKD1_k127_3571821_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000005759 150.0
HKD1_k127_3571821_4 PFAM glycosyl transferase family 9 K02849 - - 0.00000000000000001087 85.0
HKD1_k127_3571821_5 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.000000008829 64.0
HKD1_k127_3613074_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1392.0
HKD1_k127_3613074_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.794e-225 709.0
HKD1_k127_3613074_2 SpoU rRNA Methylase family K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 552.0
HKD1_k127_3613074_3 COG1226 Kef-type K transport systems K10716 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 437.0
HKD1_k127_3613074_4 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000007536 209.0
HKD1_k127_3628607_0 Probable molybdopterin binding domain K07141 - 2.7.7.76 2.377e-229 725.0
HKD1_k127_3628607_1 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 508.0
HKD1_k127_3628607_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 502.0
HKD1_k127_3628607_3 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 489.0
HKD1_k127_3628607_4 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 330.0
HKD1_k127_3628607_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007987 294.0
HKD1_k127_3628607_6 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000006629 217.0
HKD1_k127_3628607_7 XdhC and CoxI family - - - 0.00000000000000000000000000000000000000000000000000000002524 197.0
HKD1_k127_3628607_8 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000001496 194.0
HKD1_k127_3663588_0 Scaffold protein Nfu/NifU N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 303.0
HKD1_k127_3663588_1 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000001847 213.0
HKD1_k127_3663588_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000001139 139.0
HKD1_k127_3707972_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.648e-254 794.0
HKD1_k127_3707972_1 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000000000576 188.0
HKD1_k127_3707972_2 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000001101 82.0
HKD1_k127_375051_0 Amidohydrolase K07045,K14333,K15063,K20941 - 4.1.1.103,4.1.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 430.0
HKD1_k127_375051_2 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000007216 157.0
HKD1_k127_3774498_0 Putative nucleotidyltransferase substrate binding domain K02342,K07182 - 2.7.7.7 3.179e-237 753.0
HKD1_k127_3774498_1 5-aminolevulinic acid synthase K00643 - 2.3.1.37 2.015e-228 711.0
HKD1_k127_3774498_2 C-methyltransferase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 498.0
HKD1_k127_3774498_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 378.0
HKD1_k127_3774498_4 Transition state regulatory protein AbrB K07120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000104 257.0
HKD1_k127_3774498_5 - - - - 0.00000000000000000000000000000000000000000000000000000000003791 211.0
HKD1_k127_3774498_6 transferase activity, transferring glycosyl groups K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000001139 204.0
HKD1_k127_3774498_7 NUDIX domain - - - 0.00000000000000000000000000000000000000001968 158.0
HKD1_k127_3774498_8 NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000009565 130.0
HKD1_k127_3774498_9 methyltransferase - - - 0.000000000000000001025 95.0
HKD1_k127_4028028_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 368.0
HKD1_k127_4028028_1 4,5-dihydroxyphthalate decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 307.0
HKD1_k127_4028028_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000001644 160.0
HKD1_k127_4038938_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 4.325e-203 636.0
HKD1_k127_4038938_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 347.0
HKD1_k127_4038938_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 306.0
HKD1_k127_4038938_3 membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001898 278.0
HKD1_k127_4040710_0 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 3.58e-225 707.0
HKD1_k127_4040710_1 cobalamin synthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009609 555.0
HKD1_k127_4040710_10 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000001421 193.0
HKD1_k127_4040710_11 reductase K00484,K09024 - 1.5.1.36 0.00000000000000000000000000000000000000000008568 166.0
HKD1_k127_4040710_13 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000001805 73.0
HKD1_k127_4040710_14 DoxX - - - 0.0002845 49.0
HKD1_k127_4040710_2 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 484.0
HKD1_k127_4040710_3 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 447.0
HKD1_k127_4040710_4 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 378.0
HKD1_k127_4040710_5 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 329.0
HKD1_k127_4040710_6 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 313.0
HKD1_k127_4040710_7 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 302.0
HKD1_k127_4040710_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002083 281.0
HKD1_k127_4040710_9 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000002781 227.0
HKD1_k127_4041085_0 Predicted membrane protein (DUF2339) - - - 2.596e-208 666.0
HKD1_k127_4041085_1 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000001171 192.0
HKD1_k127_4041085_2 - - - - 0.00000000000000000000000000000000000000000000001779 175.0
HKD1_k127_4041085_3 Zinc-binding dehydrogenase K19745 - - 0.000000000000007452 75.0
HKD1_k127_4042209_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 544.0
HKD1_k127_4042209_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 469.0
HKD1_k127_4042209_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004616 287.0
HKD1_k127_4042209_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 281.0
HKD1_k127_4042209_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001524 262.0
HKD1_k127_4042209_5 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004011 243.0
HKD1_k127_4042209_6 PFAM cyclase family protein - - - 0.000000000000000000000000001996 111.0
HKD1_k127_4042209_7 cyclic-guanylate-specific phosphodiesterase activity - - - 0.00000000241 59.0
HKD1_k127_4049084_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 3.698e-201 634.0
HKD1_k127_4049084_1 metal-dependent hydrolase of the TIM-barrel fold K07045,K14333,K15063,K20941 - 4.1.1.103,4.1.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 456.0
HKD1_k127_4049084_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 286.0
HKD1_k127_4049084_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.000000000000000000000000000000000000000000000000000000000000004818 220.0
HKD1_k127_4049084_4 Protein of unknown function (FYDLN_acid) - - - 0.0000000000000000000000000005881 118.0
HKD1_k127_4049084_5 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000001159 91.0
HKD1_k127_4049084_6 GIY-YIG catalytic domain - - - 0.00000000000002307 75.0
HKD1_k127_4075326_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1523.0
HKD1_k127_4075326_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 4.671e-198 625.0
HKD1_k127_4075326_2 PPIC-type PPIASE domain K01802,K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 312.0
HKD1_k127_4075326_3 NUDIX domain K03574 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000001188 219.0
HKD1_k127_4075326_4 Excinuclease ABC, C subunit K07461 - - 0.000000000000000008923 83.0
HKD1_k127_4099090_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 564.0
HKD1_k127_4099090_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 372.0
HKD1_k127_4099090_2 cytochrome c peroxidase K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000002994 242.0
HKD1_k127_4099090_3 Staphylococcal nuclease homologue - - - 0.0000000000000000000000000000000000000000000000009788 186.0
HKD1_k127_4100392_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 5.404e-293 911.0
HKD1_k127_4100392_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 417.0
HKD1_k127_4101597_0 Putative peptidoglycan binding domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 474.0
HKD1_k127_4101597_1 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 295.0
HKD1_k127_4101597_2 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000001447 145.0
HKD1_k127_4103260_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 595.0
HKD1_k127_4103260_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884 435.0
HKD1_k127_4103260_10 Membrane fusogenic activity K09806 - - 0.000000000000000000000000000000001391 131.0
HKD1_k127_4103260_2 Putative S-adenosyl-L-methionine-dependent methyltransferase K00574,K18164 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 417.0
HKD1_k127_4103260_3 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 340.0
HKD1_k127_4103260_4 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 312.0
HKD1_k127_4103260_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 290.0
HKD1_k127_4103260_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 279.0
HKD1_k127_4103260_7 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000001003 183.0
HKD1_k127_4103260_8 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000001616 180.0
HKD1_k127_4103260_9 - - - - 0.00000000000000000000000000000000000001388 153.0
HKD1_k127_4103616_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 4.168e-203 644.0
HKD1_k127_4103616_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 1.005e-201 636.0
HKD1_k127_4103616_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 575.0
HKD1_k127_4103616_3 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 473.0
HKD1_k127_4103616_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 312.0
HKD1_k127_4103616_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000005273 187.0
HKD1_k127_4103616_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000006069 152.0
HKD1_k127_4109875_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 453.0
HKD1_k127_4109875_1 Biotin/lipoate A/B protein ligase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 301.0
HKD1_k127_4109875_2 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003641 241.0
HKD1_k127_4109875_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000046 222.0
HKD1_k127_4109875_4 Protein of unknown function (DUF3305) - - - 0.0000000000000000000000000000000000000000000000000000008857 200.0
HKD1_k127_4109875_5 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000001491 194.0
HKD1_k127_4109875_6 Protein of unknown function (DUF3306) - - - 0.000000000000000000000000000299 124.0
HKD1_k127_4115131_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 4.496e-222 696.0
HKD1_k127_4115131_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038,K21977 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 597.0
HKD1_k127_4115131_2 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002422 244.0
HKD1_k127_4115131_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003591 239.0
HKD1_k127_4115131_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000000001379 203.0
HKD1_k127_4115131_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000004462 201.0
HKD1_k127_4115131_6 MarR family - - - 0.00000000000000000000000000000000000000000000000000001716 192.0
HKD1_k127_4115131_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000051 180.0
HKD1_k127_4115131_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000001373 175.0
HKD1_k127_4115131_9 Activator of Hsp90 ATPase 1 family protein - - - 0.000000000000000000000000000000000000001588 153.0
HKD1_k127_4129332_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 6.248e-261 812.0
HKD1_k127_4129332_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 383.0
HKD1_k127_4129332_2 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000002611 257.0
HKD1_k127_4129332_3 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002756 277.0
HKD1_k127_4140642_0 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 325.0
HKD1_k127_4140642_1 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.000000000000000000000000000000000000000000000000000000000000004729 226.0
HKD1_k127_4140642_2 OstA-like protein K09774 - - 0.00000000000000000000000000000000000000000000000000000000005462 212.0
HKD1_k127_4140642_3 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000001339 206.0
HKD1_k127_4145810_0 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000005655 169.0
HKD1_k127_4145810_1 S1/P1 Nuclease - - - 0.0000000000000000000000000000000000000000003631 169.0
HKD1_k127_4155732_0 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 615.0
HKD1_k127_4155732_1 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 549.0
HKD1_k127_4155732_2 Oxidoreductase family, C-terminal alpha/beta domain K18067 - 1.3.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 438.0
HKD1_k127_4155732_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 390.0
HKD1_k127_4155732_4 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 332.0
HKD1_k127_4155732_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002106 231.0
HKD1_k127_4158183_0 Thiamine pyrophosphate enzyme, central domain - - - 2.879e-235 743.0
HKD1_k127_4158183_1 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 386.0
HKD1_k127_4158183_2 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 302.0
HKD1_k127_4158183_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009805 285.0
HKD1_k127_4158183_4 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002747 273.0
HKD1_k127_4158183_5 Transglycosylase SLT domain K00786,K08305 - - 0.00000000000000000000000000000000000000000000000005952 180.0
HKD1_k127_4166179_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 597.0
HKD1_k127_4166179_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 424.0
HKD1_k127_4166179_2 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 431.0
HKD1_k127_4166179_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 405.0
HKD1_k127_4166179_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 368.0
HKD1_k127_4166179_5 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 355.0
HKD1_k127_4166179_6 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 347.0
HKD1_k127_4166179_7 transcriptional regulator - - - 0.00000000000000000000000000000006634 134.0
HKD1_k127_4166179_8 branched-chain amino acid - - - 0.00000000000000000000000000004806 126.0
HKD1_k127_4171942_0 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 327.0
HKD1_k127_4171942_1 Belongs to the RNase T2 family K01166,K01169 - 3.1.27.1,3.1.27.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001227 274.0
HKD1_k127_4171942_2 Outer membrane protein beta-barrel domain K16079 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000304 184.0
HKD1_k127_4171942_3 - - - - 0.00000000000000000000000000000000000000000000005121 173.0
HKD1_k127_4171942_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K16079 - - 0.00000000000000000000000000000000000000000009596 166.0
HKD1_k127_4171942_5 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000000002341 141.0
HKD1_k127_4171942_6 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000002157 64.0
HKD1_k127_4175226_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087,K03520,K04108 - 1.17.1.4,1.2.5.3,1.3.7.9 0.0 1271.0
HKD1_k127_4175226_1 benzoate-CoA ligase K04105 - 6.2.1.25,6.2.1.27 1.925e-260 811.0
HKD1_k127_4175226_10 KR domain K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 316.0
HKD1_k127_4175226_11 KR domain K07535 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 290.0
HKD1_k127_4175226_12 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006357 273.0
HKD1_k127_4175226_13 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K04107 - 1.2.5.3,1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003028 270.0
HKD1_k127_4175226_14 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004641 263.0
HKD1_k127_4175226_15 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000000000000001717 194.0
HKD1_k127_4175226_16 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000004562 190.0
HKD1_k127_4175226_17 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000005112 177.0
HKD1_k127_4175226_18 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000005843 163.0
HKD1_k127_4175226_19 ferredoxin - - - 0.00000000000000000000000000000000002638 135.0
HKD1_k127_4175226_2 benzoyl-CoA reductase K04113 - 1.3.7.8 2.213e-247 767.0
HKD1_k127_4175226_20 transcriptional regulator - - - 0.00000000000000000000000000000000002774 139.0
HKD1_k127_4175226_21 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000005344 136.0
HKD1_k127_4175226_22 benzoyl-CoA reductase K04112 - 1.3.7.8 0.00000000000000000000000000000002161 126.0
HKD1_k127_4175226_3 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 2.828e-226 709.0
HKD1_k127_4175226_4 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 550.0
HKD1_k127_4175226_5 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 501.0
HKD1_k127_4175226_6 CO dehydrogenase flavoprotein C-terminal domain K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 441.0
HKD1_k127_4175226_7 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 416.0
HKD1_k127_4175226_8 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 395.0
HKD1_k127_4175226_9 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 333.0
HKD1_k127_4182466_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 4.855e-272 887.0
HKD1_k127_4182466_1 GAF domain - - - 0.000000000000000000000000000000008354 149.0
HKD1_k127_4182466_2 Histidine kinase - - - 0.00000000000000000000000000000007567 146.0
HKD1_k127_4190562_0 MotA/TolQ/ExbB proton channel family K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 316.0
HKD1_k127_4190562_1 Cell division and transport-associated protein TolA - - - 0.000000000000000000000000000000000000000000000000000000000000001452 228.0
HKD1_k127_4190562_2 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000000000000008397 205.0
HKD1_k127_4192728_0 Involved in beta-(1-- 2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation K06147 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 4.317e-242 760.0
HKD1_k127_4192728_1 Glycosyl transferase family group 2 K03669 - - 2.148e-201 649.0
HKD1_k127_4192728_10 - - - - 0.0000000000000000000000000000004659 126.0
HKD1_k127_4192728_11 Pfam Transposase IS66 - - - 0.000000000000000000000000000003105 136.0
HKD1_k127_4192728_12 Cytochrome c - - - 0.00000000000000000000000006149 115.0
HKD1_k127_4192728_13 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000000000001579 103.0
HKD1_k127_4192728_14 - - - - 0.00000000000000000007532 103.0
HKD1_k127_4192728_15 6-pyruvoyl tetrahydropterin synthase - - - 0.00000000000003626 76.0
HKD1_k127_4192728_16 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.000000000001369 79.0
HKD1_k127_4192728_17 - - - - 0.0000000003178 65.0
HKD1_k127_4192728_18 LTXXQ motif family protein - - - 0.00025 45.0
HKD1_k127_4192728_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 580.0
HKD1_k127_4192728_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 576.0
HKD1_k127_4192728_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 458.0
HKD1_k127_4192728_5 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 435.0
HKD1_k127_4192728_6 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 426.0
HKD1_k127_4192728_7 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 425.0
HKD1_k127_4192728_8 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 287.0
HKD1_k127_4192728_9 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007286 243.0
HKD1_k127_4201718_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.003e-244 764.0
HKD1_k127_4201718_1 Pyrogallol hydroxytransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 323.0
HKD1_k127_4201718_2 Crp-like helix-turn-helix domain K13642 - - 0.000000000000000000000000000000000000000000000000000000000009122 216.0
HKD1_k127_4201718_3 Vitamin k epoxide reductase - - - 0.000000000000000000000000000000000000000000000000004584 187.0
HKD1_k127_4201718_4 DoxX K15977 - - 0.00000000000000001413 88.0
HKD1_k127_4209121_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 401.0
HKD1_k127_4209121_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000000000000003888 254.0
HKD1_k127_4209121_2 - - - - 0.00000000000000000000000000000000000000000001265 166.0
HKD1_k127_4215676_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 590.0
HKD1_k127_4215676_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000004583 68.0
HKD1_k127_4217831_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.719e-238 743.0
HKD1_k127_4217831_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 315.0
HKD1_k127_4217831_2 oxidation-reduction process K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000000000000001134 210.0
HKD1_k127_4217831_3 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000000001522 203.0
HKD1_k127_4217831_4 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000000000786 132.0
HKD1_k127_4217831_5 - - - - 0.00001248 50.0
HKD1_k127_4230068_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 8.947e-315 977.0
HKD1_k127_4230068_1 (ABC) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 365.0
HKD1_k127_4230068_2 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001501 228.0
HKD1_k127_4230068_3 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000000000001811 153.0
HKD1_k127_4230068_4 Outer membrane protein beta-barrel domain K16079 - - 0.000000000000000000000000000009848 126.0
HKD1_k127_4244728_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 479.0
HKD1_k127_4244728_1 Putative diguanylate phosphodiesterase K13593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 438.0
HKD1_k127_4244728_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 374.0
HKD1_k127_4244728_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 334.0
HKD1_k127_4244728_4 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 340.0
HKD1_k127_4244728_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 314.0
HKD1_k127_4244728_6 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 308.0
HKD1_k127_4244728_7 Response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000006472 209.0
HKD1_k127_4283109_0 Oxidoreductase family, NAD-binding Rossmann fold - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019321,GO:0019323,GO:0022607,GO:0036094,GO:0042732,GO:0042843,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046872,GO:0046914,GO:0047837,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 370.0
HKD1_k127_4283109_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 352.0
HKD1_k127_4283109_2 Creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000001271 222.0
HKD1_k127_4287721_0 Phosphorylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 455.0
HKD1_k127_4287721_1 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 379.0
HKD1_k127_4287721_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001722 247.0
HKD1_k127_4287721_3 - - - - 0.0000000000000000000000000000000000000000000000000000002357 198.0
HKD1_k127_4287721_4 Glycosyltransferase family 87 - - - 0.000000001291 61.0
HKD1_k127_4292250_0 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 450.0
HKD1_k127_4292250_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 426.0
HKD1_k127_4292250_2 Sterol carrier protein - - - 0.0000000000000000000000000000004257 127.0
HKD1_k127_4292250_3 - - - - 0.0000000000000000000537 93.0
HKD1_k127_4292250_4 RNA polymerase sigma factor RpoH K03089 - - 0.000000000009222 65.0
HKD1_k127_4299354_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01271 - 3.4.13.9 4.556e-208 654.0
HKD1_k127_4299354_1 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 552.0
HKD1_k127_4299354_10 ATPases associated with a variety of cellular activities K02049,K10831 GO:0003674,GO:0003824,GO:0005215,GO:0005342,GO:0005368,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0008559,GO:0015075,GO:0015238,GO:0015399,GO:0015405,GO:0015411,GO:0015711,GO:0015734,GO:0015849,GO:0015893,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033283,GO:0034220,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042908,GO:0042910,GO:0043492,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072348,GO:0098656,GO:1901682,GO:1903825 3.6.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000007414 268.0
HKD1_k127_4299354_11 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004331 260.0
HKD1_k127_4299354_12 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.000000000000000000000000000000000000000000000000007109 193.0
HKD1_k127_4299354_13 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000011 179.0
HKD1_k127_4299354_14 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.000000000000000000000000000000000000000000004383 175.0
HKD1_k127_4299354_15 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000005284 119.0
HKD1_k127_4299354_16 Psort location Cytoplasmic, score 8.87 K02051,K15553 GO:0003674,GO:0005215 - 0.0000000006822 70.0
HKD1_k127_4299354_2 PFAM amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 510.0
HKD1_k127_4299354_3 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 458.0
HKD1_k127_4299354_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 435.0
HKD1_k127_4299354_5 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 331.0
HKD1_k127_4299354_6 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 313.0
HKD1_k127_4299354_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 304.0
HKD1_k127_4299354_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001422 281.0
HKD1_k127_4299354_9 cobalamin synthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004856 279.0
HKD1_k127_4352509_0 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 501.0
HKD1_k127_4352509_1 Molybdenum cofactor synthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008688 498.0
HKD1_k127_4352509_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 463.0
HKD1_k127_4352509_3 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 416.0
HKD1_k127_4352509_4 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 368.0
HKD1_k127_4352509_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000002381 269.0
HKD1_k127_4352509_6 Molybdopterin guanine dinucleotide synthesis protein B K03753 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000006664 228.0
HKD1_k127_4374643_0 Protein of unknown function (DUF3376) - - - 0.0 1045.0
HKD1_k127_4374643_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 611.0
HKD1_k127_4374643_2 Oxidoreductase molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 405.0
HKD1_k127_4374643_3 Cytochrome c - - - 0.0000000000000000004593 89.0
HKD1_k127_4374643_4 Prokaryotic cytochrome b561 - - - 0.000000000000001178 76.0
HKD1_k127_4374643_5 - - - - 0.0005154 48.0
HKD1_k127_4385080_0 Major Facilitator Superfamily K02575 - - 0.0 1565.0
HKD1_k127_4385080_1 Transglycosylase SLT domain K00786,K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 541.0
HKD1_k127_4385080_2 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 475.0
HKD1_k127_4385080_3 tRNA synthetases class II (D, K and N) K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 472.0
HKD1_k127_4385080_4 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 473.0
HKD1_k127_4385080_5 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 361.0
HKD1_k127_4385080_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 304.0
HKD1_k127_4385080_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 301.0
HKD1_k127_4401656_0 Phage portal protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 562.0
HKD1_k127_4401656_1 Caudovirus prohead serine protease K06904 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002286 253.0
HKD1_k127_4401656_2 PRC-barrel domain - - - 0.0000000000000000000000000000000000007437 148.0
HKD1_k127_4401656_3 - - - - 0.0000000000000000000006078 100.0
HKD1_k127_4401656_4 - - - - 0.00000000000000000001075 94.0
HKD1_k127_4401656_5 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000006032 54.0
HKD1_k127_4401656_6 - - - - 0.00001032 50.0
HKD1_k127_4401656_7 Protein of unknown function (DUF3618) - - - 0.0003183 51.0
HKD1_k127_4426845_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 433.0
HKD1_k127_4426845_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 320.0
HKD1_k127_4426845_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0033218,GO:0042277,GO:0043167,GO:0043168,GO:0043295,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0055114,GO:0072341,GO:1900750,GO:1901681 - 0.000000000000000000000000004166 112.0
HKD1_k127_4426845_3 Methionine synthase K00549 - 2.1.1.14 0.0000000001061 62.0
HKD1_k127_4470962_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 8.529e-271 842.0
HKD1_k127_4470962_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein - - - 7.394e-202 644.0
HKD1_k127_4470962_2 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 529.0
HKD1_k127_4470962_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001278 283.0
HKD1_k127_4470962_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000002454 213.0
HKD1_k127_4470962_5 Belongs to the HesB IscA family K13628,K15724 - - 0.000000000000000000000000000000000000000000000001347 177.0
HKD1_k127_4487375_0 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 446.0
HKD1_k127_4487375_1 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 421.0
HKD1_k127_4487375_2 COG3639 ABC-type phosphate phosphonate transport system, permease component - - - 0.0000000000000000000000008939 105.0
HKD1_k127_4487375_3 3-beta hydroxysteroid dehydrogenase/isomerase family K18981 - 1.1.1.203 0.0000000007188 60.0
HKD1_k127_45017_0 AMP-binding enzyme C-terminal domain K00666,K02182,K20034 - 6.2.1.44,6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 569.0
HKD1_k127_45017_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 306.0
HKD1_k127_45017_2 Extensin-like protein C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000003955 231.0
HKD1_k127_45017_3 Outer membrane protein beta-barrel domain K16079 - - 0.000000000000000000000000000000001096 139.0
HKD1_k127_4506888_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 532.0
HKD1_k127_4506888_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 502.0
HKD1_k127_4506888_2 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 424.0
HKD1_k127_4506888_3 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001806 280.0
HKD1_k127_4506888_4 epoxide hydrolase K01253,K21159 - 3.3.2.9 0.000000000000000000000000000000000000000000000000000000000000002512 224.0
HKD1_k127_4508621_0 Belongs to the peptidase S16 family - - - 4.625e-314 981.0
HKD1_k127_4508621_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.198e-273 847.0
HKD1_k127_4508621_2 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 445.0
HKD1_k127_4508621_3 RTCB protein K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000002722 219.0
HKD1_k127_4508621_4 - - - - 0.00000000000000000000000001812 119.0
HKD1_k127_4515997_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 7.712e-211 660.0
HKD1_k127_4515997_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 561.0
HKD1_k127_4515997_2 Chorismate mutase type II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 368.0
HKD1_k127_4515997_3 methionine biosynthesis protein (MetW) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 346.0
HKD1_k127_4515997_4 CHAP domain - - - 0.00000000000000000002022 97.0
HKD1_k127_4515997_5 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.00000000000004926 74.0
HKD1_k127_46399_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.431e-243 760.0
HKD1_k127_46399_1 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 561.0
HKD1_k127_46399_10 Protease inhibitor Inh - - - 0.00000000000000000000000000000000000000000000000000007142 194.0
HKD1_k127_46399_2 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 464.0
HKD1_k127_46399_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 415.0
HKD1_k127_46399_4 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 408.0
HKD1_k127_46399_5 NAD dependent epimerase/dehydratase family K21883 - 1.1.1.401 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 371.0
HKD1_k127_46399_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 358.0
HKD1_k127_46399_7 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 320.0
HKD1_k127_46399_8 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000361 289.0
HKD1_k127_46399_9 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000002442 226.0
HKD1_k127_465295_0 ATP-dependent helicase K03579 - 3.6.4.13 0.0 1100.0
HKD1_k127_465295_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 4.104e-226 708.0
HKD1_k127_465295_2 UDP binding domain K00012 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 5.499e-223 696.0
HKD1_k127_465295_3 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 432.0
HKD1_k127_465295_4 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 358.0
HKD1_k127_465295_5 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000000000008039 182.0
HKD1_k127_4664340_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1290.0
HKD1_k127_4664340_1 GMC oxidoreductase K00108 - 1.1.99.1 4.305e-249 779.0
HKD1_k127_4664340_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 404.0
HKD1_k127_4664340_3 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 319.0
HKD1_k127_4664340_4 Penicillin-insensitive murein endopeptidase K07261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 312.0
HKD1_k127_4664340_5 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000256 201.0
HKD1_k127_4664340_6 Yip1 domain - - - 0.00000000000000000000000000000000000007929 149.0
HKD1_k127_4667618_0 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 420.0
HKD1_k127_4667618_1 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 419.0
HKD1_k127_4667618_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 385.0
HKD1_k127_4667618_3 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 371.0
HKD1_k127_4667618_4 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 361.0
HKD1_k127_4667618_5 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 344.0
HKD1_k127_4667618_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000003873 173.0
HKD1_k127_4704774_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 2.577e-216 696.0
HKD1_k127_4704774_1 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 9.749e-215 676.0
HKD1_k127_4704774_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 427.0
HKD1_k127_4704774_3 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 389.0
HKD1_k127_4704774_4 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 371.0
HKD1_k127_4704774_5 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 368.0
HKD1_k127_4704774_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000106 239.0
HKD1_k127_4704774_7 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000002379 221.0
HKD1_k127_4704774_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000008141 87.0
HKD1_k127_4735114_0 Amidohydrolase family K01465 - 3.5.2.3 8.983e-237 737.0
HKD1_k127_4735114_1 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 349.0
HKD1_k127_4735114_2 glycosylase i K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 322.0
HKD1_k127_4735114_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 295.0
HKD1_k127_4735114_4 Protein of unknown function (DUF2385) - - - 0.0000000000000000000000000000000000000000000000001489 177.0
HKD1_k127_4735114_5 protein tyrosine phosphatase - - - 0.000000000000000000000000000000002376 137.0
HKD1_k127_4735114_6 - - - - 0.0000000000000000000000000000003521 124.0
HKD1_k127_4739008_0 FAD linked oxidases, C-terminal domain K00102 GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0004458,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006089,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016053,GO:0016491,GO:0016614,GO:0016898,GO:0019249,GO:0019516,GO:0019752,GO:0022900,GO:0022904,GO:0030447,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046394,GO:0048037,GO:0050660,GO:0050662,GO:0051990,GO:0055114,GO:0071704,GO:0071949,GO:0072330,GO:0097159,GO:0099615,GO:1901265,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.2.4 3.361e-195 618.0
HKD1_k127_4739008_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 403.0
HKD1_k127_4739008_2 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 326.0
HKD1_k127_4739008_3 NUDIX domain - - - 0.0000000000000000000000000000000000000000000002059 172.0
HKD1_k127_4739008_4 - - - - 0.0000000000000000000000000000000000000004801 159.0
HKD1_k127_4739008_5 Protein of unknown function (DUF2385) - - - 0.00000000000000000001169 94.0
HKD1_k127_4739008_6 L,D-transpeptidase catalytic domain - - - 0.000000000001206 71.0
HKD1_k127_48246_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 2.426e-237 738.0
HKD1_k127_48246_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 1.177e-207 651.0
HKD1_k127_48246_2 Zinc-binding dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 455.0
HKD1_k127_48246_3 PAP2 superfamily K12978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005147 274.0
HKD1_k127_48246_4 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000239 264.0
HKD1_k127_48246_5 invasion associated locus B - - - 0.000000000000000000000000000000000000000000000000000000000006462 212.0
HKD1_k127_48246_6 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000729 139.0
HKD1_k127_48246_7 - - - - 0.00000000000000000000000006705 113.0
HKD1_k127_48246_8 Peptidase M48 - - - 0.000000000000000000000005426 106.0
HKD1_k127_48246_9 - - - - 0.00000000000000000000001375 108.0
HKD1_k127_4838867_0 WD domain, G-beta repeat K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 411.0
HKD1_k127_4838867_1 MoeA C-terminal region (domain IV) - - - 0.0000000000000000000000000000000000000000000000000000000000000004228 223.0
HKD1_k127_4874158_0 Cys/Met metabolism PLP-dependent enzyme K01738,K01740 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47,2.5.1.49 4.433e-220 687.0
HKD1_k127_4874158_1 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 355.0
HKD1_k127_4874158_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006482 269.0
HKD1_k127_4874158_3 Ribosomal protein S9/S16 K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008133 263.0
HKD1_k127_4874158_4 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000005484 249.0
HKD1_k127_4874158_5 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000005755 227.0
HKD1_k127_4874158_6 - - - - 0.00000000000000000000000000000000000000000000003018 173.0
HKD1_k127_4874158_7 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000001649 163.0
HKD1_k127_4874158_8 Protein of unknown function (DUF3175) - - - 0.000000000000000000000009275 103.0
HKD1_k127_4908720_0 COG0451 Nucleoside-diphosphate-sugar epimerases K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 456.0
HKD1_k127_4908720_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 346.0
HKD1_k127_49197_0 Type II/IV secretion system protein K02283 - - 6.915e-233 727.0
HKD1_k127_49197_1 Sugar (and other) transporter K08369 - - 8.921e-223 698.0
HKD1_k127_49197_2 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 390.0
HKD1_k127_49197_3 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 357.0
HKD1_k127_49197_4 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 362.0
HKD1_k127_49197_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 297.0
HKD1_k127_49197_6 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000009258 246.0
HKD1_k127_49197_7 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000001381 164.0
HKD1_k127_4929911_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01469 - 3.5.2.9 0.0 1657.0
HKD1_k127_4937801_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 6.173e-273 847.0
HKD1_k127_4937801_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 5.125e-226 708.0
HKD1_k127_4937801_2 Sigma-70 factor, region 1.2 K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 489.0
HKD1_k127_4937801_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 409.0
HKD1_k127_4937801_4 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 394.0
HKD1_k127_5033240_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941,K18824 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 367.0
HKD1_k127_5033240_1 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006648 274.0
HKD1_k127_5033240_2 Domain of unknown function (DUF4332) - - - 0.0000000000000000000000000000000000000000004439 162.0
HKD1_k127_5033240_3 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000001059 160.0
HKD1_k127_5033240_4 - - - - 0.000000000000000000000000000000000002362 140.0
HKD1_k127_5051569_0 Tripartite tricarboxylate transporter TctA family - - - 1.071e-264 826.0
HKD1_k127_5051569_1 Hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 5.628e-257 818.0
HKD1_k127_5051569_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 383.0
HKD1_k127_5051569_11 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 383.0
HKD1_k127_5051569_12 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 380.0
HKD1_k127_5051569_13 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0047369 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 299.0
HKD1_k127_5051569_14 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 304.0
HKD1_k127_5051569_15 methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000004287 243.0
HKD1_k127_5051569_16 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000006719 240.0
HKD1_k127_5051569_17 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000003748 172.0
HKD1_k127_5051569_18 (Lipo)protein K04754 - - 0.000000000000000000000000000000000000000012 164.0
HKD1_k127_5051569_19 PFAM purine or other phosphorylase family 1 K01243 - 3.2.2.9 0.00000000000000000000000000000000000000001316 163.0
HKD1_k127_5051569_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 4.309e-248 777.0
HKD1_k127_5051569_20 MlaC protein - - - 0.0000000000000000000000000000000000001071 151.0
HKD1_k127_5051569_21 DsrE/DsrF-like family - - - 0.00000000000000000000000006099 114.0
HKD1_k127_5051569_22 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000004681 85.0
HKD1_k127_5051569_23 - - - - 0.0000000351 61.0
HKD1_k127_5051569_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 482.0
HKD1_k127_5051569_4 mandelate racemase muconate lactonizing K22209 - 4.2.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 462.0
HKD1_k127_5051569_5 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 426.0
HKD1_k127_5051569_6 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 416.0
HKD1_k127_5051569_7 Branched-chain amino acid transport system permease K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 410.0
HKD1_k127_5051569_8 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 387.0
HKD1_k127_5051569_9 Branched-chain amino acid transport K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 392.0
HKD1_k127_5053007_0 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 479.0
HKD1_k127_5053007_1 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004357 266.0
HKD1_k127_5066640_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 4.605e-205 646.0
HKD1_k127_5066640_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 463.0
HKD1_k127_5066640_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 332.0
HKD1_k127_5066640_3 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007294 249.0
HKD1_k127_5066640_4 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000004706 145.0
HKD1_k127_5070924_0 Sodium:solute symporter family K14393 - - 0.0 1186.0
HKD1_k127_5070924_1 - - - - 0.0000000000000000000000000000000000000000598 156.0
HKD1_k127_5070924_2 - - - - 0.0000000000000000000000000000000002935 134.0
HKD1_k127_5070924_3 - - - - 0.000000000000000000000000000002201 124.0
HKD1_k127_5070924_4 - - - - 0.00002225 51.0
HKD1_k127_5072623_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 477.0
HKD1_k127_5072623_1 DNA polymerase III delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 397.0
HKD1_k127_5072623_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000496 269.0
HKD1_k127_5072623_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000002905 134.0
HKD1_k127_5072623_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000223 53.0
HKD1_k127_5073785_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.0 1086.0
HKD1_k127_5073785_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 0.0 1074.0
HKD1_k127_5073785_10 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 423.0
HKD1_k127_5073785_11 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 409.0
HKD1_k127_5073785_12 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 382.0
HKD1_k127_5073785_13 Branched-chain amino acid ATP-binding cassette transporter K01995 GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 380.0
HKD1_k127_5073785_14 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 318.0
HKD1_k127_5073785_15 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 310.0
HKD1_k127_5073785_16 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 311.0
HKD1_k127_5073785_17 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0030266,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000001433 237.0
HKD1_k127_5073785_18 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000000000000347 179.0
HKD1_k127_5073785_2 PAS fold K07716 - 2.7.13.3 5.568e-298 932.0
HKD1_k127_5073785_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 1.691e-194 616.0
HKD1_k127_5073785_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 612.0
HKD1_k127_5073785_5 Cytochrome c-type biogenesis protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 601.0
HKD1_k127_5073785_6 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 541.0
HKD1_k127_5073785_7 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 487.0
HKD1_k127_5073785_8 Dimerisation domain of Zinc Transporter K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 458.0
HKD1_k127_5074946_0 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 535.0
HKD1_k127_5074946_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 334.0
HKD1_k127_5077743_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 2072.0
HKD1_k127_5077743_1 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0 1184.0
HKD1_k127_5077743_10 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 347.0
HKD1_k127_5077743_11 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009955 342.0
HKD1_k127_5077743_12 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 304.0
HKD1_k127_5077743_13 NADH ubiquinone oxidoreductase subunit NDUFA12 K00356 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000003199 250.0
HKD1_k127_5077743_14 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002243 246.0
HKD1_k127_5077743_15 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000001446 208.0
HKD1_k127_5077743_16 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000000000000000000000007568 187.0
HKD1_k127_5077743_17 cheY-homologous receiver domain - - - 0.00000000000000000000005722 106.0
HKD1_k127_5077743_18 - - - - 0.0000003642 61.0
HKD1_k127_5077743_19 - - - - 0.0002496 43.0
HKD1_k127_5077743_2 Biotin carboxylase C-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 1.99e-254 789.0
HKD1_k127_5077743_20 - - - - 0.0005016 42.0
HKD1_k127_5077743_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 8.165e-234 754.0
HKD1_k127_5077743_4 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 591.0
HKD1_k127_5077743_5 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 572.0
HKD1_k127_5077743_6 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 484.0
HKD1_k127_5077743_7 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 416.0
HKD1_k127_5077743_8 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 377.0
HKD1_k127_5077743_9 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 369.0
HKD1_k127_5091691_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.134e-285 888.0
HKD1_k127_5091691_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 4.919e-269 841.0
HKD1_k127_5091691_10 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003956 248.0
HKD1_k127_5091691_11 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000008522 225.0
HKD1_k127_5091691_12 NnrU protein - - - 0.000000000000000000000000000000000000000000000000000000000000372 216.0
HKD1_k127_5091691_13 Belongs to the ArsC family K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.00000000000000000000000000000000000000000000000004379 185.0
HKD1_k127_5091691_14 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000002824 150.0
HKD1_k127_5091691_15 MAPEG family - - - 0.00000000000000000000000000000000000007849 146.0
HKD1_k127_5091691_16 - - - - 0.000000000000006584 81.0
HKD1_k127_5091691_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 4.989e-251 782.0
HKD1_k127_5091691_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.658e-200 639.0
HKD1_k127_5091691_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 542.0
HKD1_k127_5091691_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 439.0
HKD1_k127_5091691_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 392.0
HKD1_k127_5091691_7 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 335.0
HKD1_k127_5091691_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 314.0
HKD1_k127_5091691_9 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 305.0
HKD1_k127_5092657_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 4.643e-282 878.0
HKD1_k127_5092657_1 His Kinase A (phosphoacceptor) domain - - - 3.066e-195 620.0
HKD1_k127_5092657_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 515.0
HKD1_k127_5092657_3 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000001166 212.0
HKD1_k127_5092657_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000000000003524 147.0
HKD1_k127_5092657_5 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000001195 138.0
HKD1_k127_5092657_6 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000000009143 80.0
HKD1_k127_5092893_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 479.0
HKD1_k127_5092893_1 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 423.0
HKD1_k127_5092893_2 PFAM Amidohydrolase 2 K10221 - 3.1.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 344.0
HKD1_k127_5092893_3 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000002257 237.0
HKD1_k127_5092893_4 LTXXQ motif family protein - - - 0.000000000000000000000000000000000000000000000000001796 193.0
HKD1_k127_5092893_5 Protein of unknown function (DUF3225) - - - 0.000000000000000000000000000000003096 131.0
HKD1_k127_5093274_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 5.153e-285 878.0
HKD1_k127_5093274_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 5.979e-257 796.0
HKD1_k127_5093274_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 591.0
HKD1_k127_5093274_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 569.0
HKD1_k127_5093274_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 379.0
HKD1_k127_5093274_5 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 361.0
HKD1_k127_5093274_6 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000000000000000000000000000000000000000000000000000002554 218.0
HKD1_k127_5093274_7 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000007876 122.0
HKD1_k127_5093274_8 Ribosomal protein S9/S16 K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000006205 83.0
HKD1_k127_5093274_9 - - - - 0.00000001073 57.0
HKD1_k127_5093784_0 Acetyl-CoA dehydrogenase C-terminal like K00248,K00249,K20035 - 1.3.8.1,1.3.8.7 1.239e-210 665.0
HKD1_k127_5093784_1 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000008189 74.0
HKD1_k127_5098992_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05350 - 3.2.1.21 6.94e-207 652.0
HKD1_k127_5098992_1 DNA polymerase beta thumb K02347 - - 2.597e-203 650.0
HKD1_k127_5098992_2 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 567.0
HKD1_k127_5098992_3 Beta-agarase K01219 - 3.2.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 488.0
HKD1_k127_5098992_4 ABC transporter transmembrane region 2 K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 416.0
HKD1_k127_5098992_5 belongs to the carbohydrate kinase PfkB family K16370 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009871 397.0
HKD1_k127_5098992_6 Protein of unknown function (DUF3775) - - - 0.0000000000000000000000000000000000000000000000000000000000000601 216.0
HKD1_k127_5098992_7 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000002612 171.0
HKD1_k127_5098992_8 Universal stress protein family - - - 0.000000000000000000000000000001095 126.0
HKD1_k127_5098992_9 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000002322 106.0
HKD1_k127_5099000_0 4Fe-4S binding domain - - - 5.058e-262 815.0
HKD1_k127_5099000_1 WD domain, G-beta repeat K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001262 273.0
HKD1_k127_510162_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 6.502e-302 930.0
HKD1_k127_510162_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 3.054e-194 610.0
HKD1_k127_510162_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 551.0
HKD1_k127_510162_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 535.0
HKD1_k127_510162_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 473.0
HKD1_k127_510162_5 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 293.0
HKD1_k127_510162_6 His Kinase A (phosphoacceptor) domain K07716 - 2.7.13.3 0.00000000000000000000004508 101.0
HKD1_k127_5110625_0 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 377.0
HKD1_k127_5110625_1 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.00000000000000000000000000000000000000000000001453 184.0
HKD1_k127_5110625_2 COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.0000000000002072 77.0
HKD1_k127_5115845_0 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 3.816e-279 874.0
HKD1_k127_5115845_1 phosphorylase activity K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 8.186e-261 812.0
HKD1_k127_5115845_2 PHB de-polymerase C-terminus K05973 - 3.1.1.75 3.499e-211 668.0
HKD1_k127_5115845_3 Major Facilitator Superfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 393.0
HKD1_k127_5115845_4 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 356.0
HKD1_k127_5115845_5 N-terminal domain of ribose phosphate pyrophosphokinase K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 314.0
HKD1_k127_5115845_6 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000006124 188.0
HKD1_k127_5135332_0 Acyl-CoA dehydrogenase, C-terminal domain K14448 - 1.3.8.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 559.0
HKD1_k127_5135332_1 methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 341.0
HKD1_k127_5135332_2 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000004363 179.0
HKD1_k127_5138246_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 403.0
HKD1_k127_5138246_1 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 348.0
HKD1_k127_5138246_2 PFAM amidohydrolase 2 K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003374 287.0
HKD1_k127_5138246_3 Class II aldolase adducin family protein - - - 0.000000000000000000000000000000000000000000000000000000003135 208.0
HKD1_k127_5138246_4 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000543 207.0
HKD1_k127_5138246_5 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000001073 65.0
HKD1_k127_5147160_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 3.631e-194 620.0
HKD1_k127_5147160_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 342.0
HKD1_k127_5147160_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000003116 191.0
HKD1_k127_5147160_3 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000003899 155.0
HKD1_k127_5147160_4 Dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.00006045 46.0
HKD1_k127_5149313_0 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 592.0
HKD1_k127_5149313_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 564.0
HKD1_k127_5149313_10 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000002205 179.0
HKD1_k127_5149313_11 WHG domain - - - 0.0000000000000005378 79.0
HKD1_k127_5149313_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 378.0
HKD1_k127_5149313_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 323.0
HKD1_k127_5149313_4 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001152 279.0
HKD1_k127_5149313_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000008923 237.0
HKD1_k127_5149313_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005922 234.0
HKD1_k127_5149313_7 Thioesterase superfamily K07107 - - 0.000000000000000000000000000000000000000000000000000000000000000001736 230.0
HKD1_k127_5149313_8 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000004097 225.0
HKD1_k127_5149313_9 PFAM Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000000000001608 181.0
HKD1_k127_5157364_0 Diguanylate cyclase - - - 3.58e-199 637.0
HKD1_k127_5157364_1 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 306.0
HKD1_k127_5157364_2 Sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 290.0
HKD1_k127_5157364_3 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004225 260.0
HKD1_k127_5157364_4 - - - - 0.000000000000000000000000000006561 126.0
HKD1_k127_5157364_5 Protein of unknown function (DUF4239) - - - 0.00000001881 57.0
HKD1_k127_5159974_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.177e-226 705.0
HKD1_k127_5159974_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 401.0
HKD1_k127_5159974_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000309 138.0
HKD1_k127_5178100_0 electron transfer K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 2.282e-216 679.0
HKD1_k127_5178100_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 4.908e-209 659.0
HKD1_k127_5178100_2 PFAM Xanthine uracil vitamin C permease K06901 - - 1.017e-207 653.0
HKD1_k127_5178100_3 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 481.0
HKD1_k127_5178100_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 480.0
HKD1_k127_5178100_5 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 355.0
HKD1_k127_5186991_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 569.0
HKD1_k127_5186991_1 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 450.0
HKD1_k127_5186991_2 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 447.0
HKD1_k127_5186991_3 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 446.0
HKD1_k127_5186991_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 384.0
HKD1_k127_5186991_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 313.0
HKD1_k127_5186991_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 301.0
HKD1_k127_5186991_7 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000002363 207.0
HKD1_k127_5186991_8 - - - - 0.0000000002884 63.0
HKD1_k127_5200713_0 Glycosyl transferase family 21 K00694,K01210 - 2.4.1.12,3.2.1.58 3.176e-229 721.0
HKD1_k127_5200713_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 571.0
HKD1_k127_5200713_2 beta (1-6) glucans synthase K01210 - 3.2.1.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 574.0
HKD1_k127_5200713_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009958 506.0
HKD1_k127_5200713_4 - - - - 0.00000000000000000000000000000000000000000000000005189 185.0
HKD1_k127_5200713_5 Tfp pilus assembly protein FimV - - - 0.0000000000001821 81.0
HKD1_k127_5205103_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1689.0
HKD1_k127_5205103_1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 474.0
HKD1_k127_5205103_2 Major Facilitator Superfamily - - - 0.0002115 47.0
HKD1_k127_5221308_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 9.945e-309 958.0
HKD1_k127_5221308_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07638 - 2.7.13.3 1.225e-232 728.0
HKD1_k127_5221308_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002512 232.0
HKD1_k127_5221308_11 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000006412 229.0
HKD1_k127_5221308_12 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000009683 205.0
HKD1_k127_5221308_13 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K16079 - - 0.00000000000000000000000000000000000000000000002764 178.0
HKD1_k127_5221308_14 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000000000000000004047 128.0
HKD1_k127_5221308_15 Protein of unknown function (DUF1460) - - - 0.00000000000001133 83.0
HKD1_k127_5221308_16 Putative bacterial sensory transduction regulator - - - 0.00000000006159 62.0
HKD1_k127_5221308_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 522.0
HKD1_k127_5221308_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 431.0
HKD1_k127_5221308_4 Catechol dioxygenase N terminus K03381 - 1.13.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 422.0
HKD1_k127_5221308_5 transcriptional regulator, winged helix family K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 360.0
HKD1_k127_5221308_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0003674,GO:0003824,GO:0004735,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 316.0
HKD1_k127_5221308_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 299.0
HKD1_k127_5221308_8 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 287.0
HKD1_k127_5221308_9 Outer membrane protein beta-barrel domain K16079 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000001125 247.0
HKD1_k127_5229113_0 GTP-binding protein TypA K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.0 1033.0
HKD1_k127_5229113_1 Peptidase family M50 K06402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 478.0
HKD1_k127_5229113_2 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 306.0
HKD1_k127_5229113_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000005345 154.0
HKD1_k127_5229113_4 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000001528 151.0
HKD1_k127_5229113_5 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000001797 146.0
HKD1_k127_5229113_6 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001,K00344 - 1.1.1.1,1.6.5.5 0.00000000000000000000000000000000002832 136.0
HKD1_k127_523190_0 cystathionine beta-lyase K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 567.0
HKD1_k127_523190_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 385.0
HKD1_k127_5246594_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 363.0
HKD1_k127_5246594_1 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 286.0
HKD1_k127_5246594_2 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.0000000000000000000000000002189 115.0
HKD1_k127_5250058_0 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 443.0
HKD1_k127_5250058_1 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 418.0
HKD1_k127_5250058_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 308.0
HKD1_k127_5250058_3 Cys/Met metabolism PLP-dependent enzyme K01738,K01740 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47,2.5.1.49 0.00000000000000000000000000000000000000001991 153.0
HKD1_k127_5250058_4 Protein of unknown function (DUF2842) - - - 0.000000000000000001524 87.0
HKD1_k127_5264021_0 His Kinase A (phosphoacceptor) domain K07716,K11357 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 577.0
HKD1_k127_5264021_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002002 243.0
HKD1_k127_5264021_10 - - - - 0.000001232 53.0
HKD1_k127_5264021_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000001634 224.0
HKD1_k127_5264021_3 Fe-S metabolism associated domain K02426 - - 0.00000000000000000000000000000000000000000000000000000000001629 211.0
HKD1_k127_5264021_4 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000000000000000000000000000000000000000006347 171.0
HKD1_k127_5264021_5 Protein of unknown function (DUF1491) - - - 0.000000000000000000000000000000000000000000876 159.0
HKD1_k127_5264021_6 - - - - 0.00000000000000000000000000000000000005326 149.0
HKD1_k127_5264021_7 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000001545 147.0
HKD1_k127_5264021_8 Family of unknown function (DUF5330) - - - 0.000000000000000000000007699 106.0
HKD1_k127_5264021_9 - - - - 0.0000000000000003467 78.0
HKD1_k127_5266432_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.362e-200 631.0
HKD1_k127_5266432_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 566.0
HKD1_k127_5266432_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 380.0
HKD1_k127_5266432_3 Etoposide-induced protein 2.4 (EI24) K06203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001618 278.0
HKD1_k127_5278030_0 Urease alpha-subunit, N-terminal domain K01428 - 3.5.1.5 0.0 1049.0
HKD1_k127_5278030_1 CobW/HypB/UreG, nucleotide-binding domain K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 374.0
HKD1_k127_5278030_2 UreF K03188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 323.0
HKD1_k127_5278030_3 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 307.0
HKD1_k127_5278030_4 Urease beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000005025 224.0
HKD1_k127_5278030_5 UreD urease accessory protein K03190 - - 0.0000000000000000000000000000000000000000000000000000000003021 208.0
HKD1_k127_5278030_6 Urease, gamma subunit K01430 - 3.5.1.5 0.0000000000000000000000000000000000000000000000002029 177.0
HKD1_k127_5278030_7 HupE / UreJ protein K03192 - - 0.00000000001972 66.0
HKD1_k127_5280293_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1153.0
HKD1_k127_5280293_1 Participates in both transcription termination and antitermination K02600 - - 4.341e-283 876.0
HKD1_k127_5280293_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 518.0
HKD1_k127_5280293_3 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 495.0
HKD1_k127_5280293_4 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006863 257.0
HKD1_k127_5280293_5 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000000000000000000000000000000000000000000004394 222.0
HKD1_k127_5280293_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000000000002449 196.0
HKD1_k127_5280293_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000001548 142.0
HKD1_k127_5287892_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.611e-224 709.0
HKD1_k127_5287892_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 295.0
HKD1_k127_5287892_2 - - - - 0.000001069 53.0
HKD1_k127_5292273_0 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 332.0
HKD1_k127_5292273_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 306.0
HKD1_k127_5292273_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001438 286.0
HKD1_k127_5292273_3 Cupin domain - - - 0.0000000000000000000000000000000000000000000004861 171.0
HKD1_k127_5292273_4 SET domain K07117 - - 0.00000000000000000000002576 103.0
HKD1_k127_5292797_0 Belongs to the TPP enzyme family K01577,K01652 - 2.2.1.6,4.1.1.8 7.444e-222 692.0
HKD1_k127_5292797_1 Tripartite tricarboxylate transporter TctA family K07793 - - 1.23e-208 652.0
HKD1_k127_5292797_2 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 312.0
HKD1_k127_5293758_0 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0 1244.0
HKD1_k127_5293758_1 Thiamine pyrophosphate enzyme, central domain - - - 6.824e-287 892.0
HKD1_k127_5293758_2 Periplasmic binding protein K01999 - - 8.456e-221 690.0
HKD1_k127_5293758_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 471.0
HKD1_k127_5293758_4 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 391.0
HKD1_k127_5293758_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000004457 149.0
HKD1_k127_5321745_0 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 392.0
HKD1_k127_5321745_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003922 273.0
HKD1_k127_5321745_2 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000001086 223.0
HKD1_k127_5321745_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0006157 42.0
HKD1_k127_5347945_0 Sugar (and other) transporter - - - 2.836e-241 749.0
HKD1_k127_5347945_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 338.0
HKD1_k127_5347945_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000001062 204.0
HKD1_k127_5347945_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) K02109 - - 0.000000000000000000000000000000000000000000000000007253 186.0
HKD1_k127_5347945_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000000001118 166.0
HKD1_k127_5347945_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000007596 136.0
HKD1_k127_5347945_6 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00000000000000000000000000000003967 129.0
HKD1_k127_5347945_7 - - - - 0.000000000000003653 84.0
HKD1_k127_5356897_0 Isocitrate/isopropylmalate dehydrogenase K00052 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 580.0
HKD1_k127_5356897_1 Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 542.0
HKD1_k127_5356897_10 Flavodoxin-like fold K19784 - - 0.00000000000000000000000000000000000000000000000000000000000000000005363 236.0
HKD1_k127_5356897_11 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000427 227.0
HKD1_k127_5356897_12 TRAP transporter, solute receptor (TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000005841 234.0
HKD1_k127_5356897_13 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000000000001173 181.0
HKD1_k127_5356897_14 YCII-related domain K09780 - - 0.0000000000000000001237 91.0
HKD1_k127_5356897_15 DoxX K15977 - - 0.0000000000000000009365 91.0
HKD1_k127_5356897_2 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 511.0
HKD1_k127_5356897_3 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 374.0
HKD1_k127_5356897_4 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 370.0
HKD1_k127_5356897_5 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 339.0
HKD1_k127_5356897_6 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 293.0
HKD1_k127_5356897_7 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007507 277.0
HKD1_k127_5356897_8 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000001872 268.0
HKD1_k127_5356897_9 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008165 257.0
HKD1_k127_5372897_0 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001319 288.0
HKD1_k127_5372897_1 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004145 228.0
HKD1_k127_5372897_2 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000008067 194.0
HKD1_k127_5372897_3 - - - - 0.000000000000000000000000000000003766 137.0
HKD1_k127_5372897_4 Patatin-like phospholipase - - - 0.000000000000000000002795 94.0
HKD1_k127_5372897_6 - - - - 0.0000000000000002814 84.0
HKD1_k127_5380376_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 2.147e-243 756.0
HKD1_k127_5380376_1 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 493.0
HKD1_k127_5380376_2 CopC domain K07156 - - 0.000000000000000000000001782 106.0
HKD1_k127_5380376_3 Copper resistance protein D K07245 - - 0.000000000000002719 80.0
HKD1_k127_5435503_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 3.113e-236 734.0
HKD1_k127_5435503_1 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000118 271.0
HKD1_k127_5449306_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0 1087.0
HKD1_k127_5449306_1 NADH-ubiquinone oxidoreductase subunit G, C-terminal K00336 - 1.6.5.3 0.0 1054.0
HKD1_k127_5449306_10 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005591 280.0
HKD1_k127_5449306_11 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000000000000000005407 207.0
HKD1_k127_5449306_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000002904 204.0
HKD1_k127_5449306_13 Domain of unknown function (DUF3291) - - - 0.00000000000000000000000000000000000000000000000003569 185.0
HKD1_k127_5449306_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000001292 173.0
HKD1_k127_5449306_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000001768 148.0
HKD1_k127_5449306_16 Domain of unknown function (DUF3291) - - - 0.00000000000000000000000000000000000003163 153.0
HKD1_k127_5449306_2 NADH-ubiquinone oxidoreductase chain 4, amino terminus K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 2.882e-257 805.0
HKD1_k127_5449306_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 1.738e-251 779.0
HKD1_k127_5449306_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 8.69e-245 759.0
HKD1_k127_5449306_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 584.0
HKD1_k127_5449306_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 366.0
HKD1_k127_5449306_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 324.0
HKD1_k127_5449306_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 320.0
HKD1_k127_5449306_9 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03943 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 317.0
HKD1_k127_5451270_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1296.0
HKD1_k127_5451270_1 NMT1-like family K15576 - - 3.049e-251 781.0
HKD1_k127_5451270_10 - - - - 0.000000000005531 71.0
HKD1_k127_5451270_2 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 580.0
HKD1_k127_5451270_3 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 523.0
HKD1_k127_5451270_4 ATPases associated with a variety of cellular activities K02049,K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 498.0
HKD1_k127_5451270_5 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 485.0
HKD1_k127_5451270_6 nitrate ABC transporter K02050,K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 466.0
HKD1_k127_5451270_7 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 447.0
HKD1_k127_5451270_8 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007002 276.0
HKD1_k127_5451270_9 SOS response K14160 - - 0.00000000000000000000000008431 116.0
HKD1_k127_557453_0 glutamate--cysteine ligase K01919 - 6.3.2.2 1.527e-235 734.0
HKD1_k127_557453_1 UvrD-like helicase C-terminal domain K01144 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 592.0
HKD1_k127_557453_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 436.0
HKD1_k127_557453_3 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 323.0
HKD1_k127_5578850_0 Proton-conducting membrane transporter - - - 2.121e-312 969.0
HKD1_k127_5578850_1 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 364.0
HKD1_k127_5578850_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 295.0
HKD1_k127_5578850_3 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000003698 123.0
HKD1_k127_559249_0 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 559.0
HKD1_k127_559249_1 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 553.0
HKD1_k127_559249_10 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 358.0
HKD1_k127_559249_11 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000001816 200.0
HKD1_k127_559249_12 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000005957 154.0
HKD1_k127_559249_13 - - - - 0.0000000000000000004564 90.0
HKD1_k127_559249_14 - - - - 0.00001542 50.0
HKD1_k127_559249_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 470.0
HKD1_k127_559249_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00446 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 419.0
HKD1_k127_559249_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 415.0
HKD1_k127_559249_5 Coenzyme A transferase K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 396.0
HKD1_k127_559249_6 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 383.0
HKD1_k127_559249_7 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 381.0
HKD1_k127_559249_8 Fumarylacetoacetate (FAA) hydrolase family K02509 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 379.0
HKD1_k127_559249_9 Coenzyme A transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 363.0
HKD1_k127_5628384_0 Glycosyl transferase family 41 - - - 1.137e-196 637.0
HKD1_k127_5628384_1 Belongs to the flagella basal body rod proteins family K02396 - - 1.236e-195 628.0
HKD1_k127_5628384_10 FAD dependent oxidoreductase K04755,K09471 - - 0.00000004169 56.0
HKD1_k127_5628384_2 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 535.0
HKD1_k127_5628384_3 flagellar basal body K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 482.0
HKD1_k127_5628384_4 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 439.0
HKD1_k127_5628384_5 PFAM flagellin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001358 260.0
HKD1_k127_5628384_6 PFAM flagellin domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003379 244.0
HKD1_k127_5628384_7 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000001055 221.0
HKD1_k127_5628384_8 Flagellar biosynthesis repressor FlbT K06601 - - 0.00000000000000000000000000000000000000000000000000003367 191.0
HKD1_k127_5628384_9 PFAM flagellar FlaF family protein K06602 - - 0.000000000000000000000000000000000000000005583 158.0
HKD1_k127_5638798_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 524.0
HKD1_k127_5638798_1 signal peptide peptidase SppA K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 442.0
HKD1_k127_5638798_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 291.0
HKD1_k127_5638798_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000002585 171.0
HKD1_k127_5638798_4 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000001926 154.0
HKD1_k127_5638798_5 Lipopolysaccharide assembly protein A domain - - - 0.00000000000000000000000005767 111.0
HKD1_k127_5648875_0 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 341.0
HKD1_k127_5648875_1 PFAM DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000009002 202.0
HKD1_k127_5648875_2 Cytosol aminopeptidase family, catalytic domain K01255 - 3.4.11.1 0.00000000000002292 72.0
HKD1_k127_5648875_3 Belongs to the ABC transporter superfamily K02031,K02032,K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000001835 49.0
HKD1_k127_5661043_0 His Kinase A (phosphoacceptor) domain K13587 - 2.7.13.3 0.0 1135.0
HKD1_k127_5661043_1 FlhB HrpN YscU SpaS Family K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 471.0
HKD1_k127_5661043_10 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000002419 68.0
HKD1_k127_5661043_11 PilZ domain - - - 0.00000000127 63.0
HKD1_k127_5661043_2 Role in flagellar biosynthesis K02421 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 349.0
HKD1_k127_5661043_3 import inner membrane translocase, subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 309.0
HKD1_k127_5661043_4 Belongs to the flagella basal body rod proteins family K02388 - - 0.00000000000000000000000000000000000000000000000000000000000000000075 229.0
HKD1_k127_5661043_5 Flagellar biosynthesis protein, FliO - - - 0.00000000000000000000000000000000000000000000000005743 189.0
HKD1_k127_5661043_6 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000000000000009551 154.0
HKD1_k127_5661043_7 Role in flagellar biosynthesis K02420 - - 0.000000000000000000000000000004316 121.0
HKD1_k127_5661043_8 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000000000014 116.0
HKD1_k127_5661043_9 Protein of unknown function (DUF3309) - - - 0.0000000000000000008594 88.0
HKD1_k127_5684381_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 448.0
HKD1_k127_5684381_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 388.0
HKD1_k127_5684381_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 350.0
HKD1_k127_5684381_3 Ribosomal protein S10p/S20e K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000003671 202.0
HKD1_k127_5684381_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000001365 169.0
HKD1_k127_5684381_5 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000609 166.0
HKD1_k127_5688066_0 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 446.0
HKD1_k127_5688066_1 polyphosphate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 394.0
HKD1_k127_5688066_2 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 327.0
HKD1_k127_5688066_3 Ribbon-helix-helix domain - - - 0.0000000000000000004639 92.0
HKD1_k127_5744969_0 Carbamoyl-phosphate synthase L chain K01968 - 6.4.1.4 2.731e-249 787.0
HKD1_k127_5744969_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 409.0
HKD1_k127_5744969_10 - - - - 0.000000000003539 69.0
HKD1_k127_5744969_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 325.0
HKD1_k127_5744969_3 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.000000000000000000000000000000000000000000000000000000000001092 218.0
HKD1_k127_5744969_4 Protein of unknown function (DUF1489) - - - 0.000000000000000000000000000000000000000000000000000000000811 207.0
HKD1_k127_5744969_5 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000007203 199.0
HKD1_k127_5744969_6 - - - - 0.000000000000000000000000000001056 133.0
HKD1_k127_5744969_7 - - - - 0.0000000000000000000000000005167 120.0
HKD1_k127_5744969_8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000009858 114.0
HKD1_k127_5744969_9 - - - - 0.000000000000000004391 90.0
HKD1_k127_5758861_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 4.222e-202 641.0
HKD1_k127_5758861_1 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 502.0
HKD1_k127_5758861_2 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 460.0
HKD1_k127_5758861_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 401.0
HKD1_k127_5758861_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 343.0
HKD1_k127_5758861_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 343.0
HKD1_k127_5758861_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 325.0
HKD1_k127_5758861_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 290.0
HKD1_k127_5758861_8 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000002083 235.0
HKD1_k127_5758861_9 Belongs to the Fur family K09823 - - 0.00000000000000000000000000000000000000000000000000000000000004387 217.0
HKD1_k127_5831144_0 FtsX-like permease family K02004 - - 0.0 1058.0
HKD1_k127_5831144_1 ABC transporter K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 335.0
HKD1_k127_5831144_2 Inhibitor of apoptosis-promoting Bax1 K06890 - - 0.000008864 48.0
HKD1_k127_58347_0 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 347.0
HKD1_k127_58347_1 ABC-type tungstate transport system, periplasmic component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 328.0
HKD1_k127_58347_2 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 306.0
HKD1_k127_5918919_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 379.0
HKD1_k127_5918919_1 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 338.0
HKD1_k127_5918919_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 286.0
HKD1_k127_5918919_3 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 273.0
HKD1_k127_5918919_4 Response regulator receiver - - - 0.000000000000000000000000000000000000206 144.0
HKD1_k127_5918919_5 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000381 84.0
HKD1_k127_6006892_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 548.0
HKD1_k127_6006892_1 Zinc-binding dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008462 479.0
HKD1_k127_6006892_2 Cell Wall Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 428.0
HKD1_k127_6006892_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.00000000000000000000000000000000000000000000000000000000000006591 232.0
HKD1_k127_6006892_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00065 - 1.1.1.127 0.00000000000000000000000000000000000007831 143.0
HKD1_k127_6020547_0 Hydrolase CocE NonD family K06978 - - 1.079e-284 883.0
HKD1_k127_6020547_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 343.0
HKD1_k127_6020547_10 Glutathione S-transferase, N-terminal domain K01800 - 5.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000004567 250.0
HKD1_k127_6020547_11 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000007032 242.0
HKD1_k127_6020547_12 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000002827 245.0
HKD1_k127_6020547_13 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000001206 236.0
HKD1_k127_6020547_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 334.0
HKD1_k127_6020547_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 308.0
HKD1_k127_6020547_4 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 308.0
HKD1_k127_6020547_5 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 301.0
HKD1_k127_6020547_6 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000643 286.0
HKD1_k127_6020547_7 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008288 291.0
HKD1_k127_6020547_8 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003662 283.0
HKD1_k127_6020547_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007591 262.0
HKD1_k127_604940_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008349 593.0
HKD1_k127_604940_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 482.0
HKD1_k127_604940_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 410.0
HKD1_k127_604940_3 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 406.0
HKD1_k127_604940_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000006793 256.0
HKD1_k127_604940_5 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000002108 192.0
HKD1_k127_6059972_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 6.722e-204 643.0
HKD1_k127_6059972_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001009 231.0
HKD1_k127_6059972_2 Patatin phospholipase K07001 - - 0.000000000000000000000000000003739 121.0
HKD1_k127_6065333_0 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 544.0
HKD1_k127_6065333_1 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 522.0
HKD1_k127_6065333_2 Common central domain of tyrosinase K00505 - 1.14.18.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 518.0
HKD1_k127_6065333_3 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 353.0
HKD1_k127_6065333_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 322.0
HKD1_k127_6065333_5 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000004237 223.0
HKD1_k127_6065333_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000001569 172.0
HKD1_k127_6082812_0 AcrB/AcrD/AcrF family K21134 - - 0.0 1492.0
HKD1_k127_6082812_1 SMART Elongator protein 3 MiaB NifB - - - 4.142e-265 821.0
HKD1_k127_6082812_2 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 385.0
HKD1_k127_6082812_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 362.0
HKD1_k127_6082812_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 286.0
HKD1_k127_6082812_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000002351 190.0
HKD1_k127_6082812_6 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.0000000000000000000000133 102.0
HKD1_k127_6093817_0 Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA K09461 - 1.14.13.40 0.0 1202.0
HKD1_k127_6093817_1 Lanthionine synthetase C-like protein - - - 0.0 1103.0
HKD1_k127_6093817_10 Peptidase dimerisation domain K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 417.0
HKD1_k127_6093817_11 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 406.0
HKD1_k127_6093817_12 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 400.0
HKD1_k127_6093817_13 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 393.0
HKD1_k127_6093817_14 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 366.0
HKD1_k127_6093817_15 Cyclic peptide transporter K06160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 355.0
HKD1_k127_6093817_16 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000002988 254.0
HKD1_k127_6093817_17 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000001866 242.0
HKD1_k127_6093817_18 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000002394 207.0
HKD1_k127_6093817_19 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000001166 179.0
HKD1_k127_6093817_2 benzoate-CoA ligase K08295 - 6.2.1.32 1.915e-305 944.0
HKD1_k127_6093817_20 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000004457 162.0
HKD1_k127_6093817_21 Transglycosylase associated protein - - - 0.0000000000000000000000000000007551 123.0
HKD1_k127_6093817_22 plasmid maintenance K03496 - - 0.000000000000000000000000000016 126.0
HKD1_k127_6093817_23 protein domain associated with GTPases - - - 0.00000000000000000000000000005948 123.0
HKD1_k127_6093817_24 protein domain associated with GTPases - - - 0.0000000000000000000000000005303 121.0
HKD1_k127_6093817_25 Uncharacterised nucleotidyltransferase - - - 0.00000000000000004215 87.0
HKD1_k127_6093817_26 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000349 65.0
HKD1_k127_6093817_27 Polysaccharide deacetylase - - - 0.0000001181 54.0
HKD1_k127_6093817_3 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 1.328e-283 883.0
HKD1_k127_6093817_4 Receptor family ligand binding region K01999 - - 2.647e-211 666.0
HKD1_k127_6093817_5 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 583.0
HKD1_k127_6093817_6 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 549.0
HKD1_k127_6093817_7 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 484.0
HKD1_k127_6093817_8 Protein of unknown function (DUF3095) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 432.0
HKD1_k127_6093817_9 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 422.0
HKD1_k127_6108089_0 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 454.0
HKD1_k127_6108089_1 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 285.0
HKD1_k127_6108089_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005056 287.0
HKD1_k127_6108089_3 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000000000000000000001356 235.0
HKD1_k127_6108089_4 Bacterial protein of unknown function (DUF898) - - - 0.000000000000000002317 93.0
HKD1_k127_6114275_0 Proton-conducting membrane transporter - - - 0.0 1517.0
HKD1_k127_6114275_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K21134 - - 0.0 1499.0
HKD1_k127_6114275_10 Na+/H+ antiporter subunit K05571 - - 0.0000000000000000000000000000000000000000000000000001485 188.0
HKD1_k127_6114275_11 Domain of unknown function (DUF4040) - - - 0.0000000000000000000000000000000001751 134.0
HKD1_k127_6114275_12 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340,K05567 - 1.6.5.3 0.0000000000000000918 85.0
HKD1_k127_6114275_13 antiporter activity K05570 - - 0.00000000002995 70.0
HKD1_k127_6114275_14 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0001846 44.0
HKD1_k127_6114275_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 556.0
HKD1_k127_6114275_3 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 502.0
HKD1_k127_6114275_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K21136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 483.0
HKD1_k127_6114275_5 Na H antiporter, MnhB K05566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 363.0
HKD1_k127_6114275_6 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 352.0
HKD1_k127_6114275_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 295.0
HKD1_k127_6114275_8 Na+/H+ ion antiporter subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004584 267.0
HKD1_k127_6114275_9 Protein of unknown function (DUF3611) - - - 0.000000000000000000000000000000000000000000000000000000001628 206.0
HKD1_k127_6116443_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4 4.899e-284 889.0
HKD1_k127_6116443_1 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 4.519e-197 619.0
HKD1_k127_6116443_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 525.0
HKD1_k127_6116443_3 phosphate acetyltransferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 434.0
HKD1_k127_6116443_4 FixH - - - 0.00000000000000000000000000008536 119.0
HKD1_k127_6116443_5 Cytochrome oxidase maturation protein cbb3-type - - - 0.000000000000003484 81.0
HKD1_k127_6116749_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 1.006e-314 974.0
HKD1_k127_6116749_1 Periplasmic binding protein domain - - - 1.248e-234 734.0
HKD1_k127_6116749_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 3.618e-197 619.0
HKD1_k127_6116749_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 500.0
HKD1_k127_6116749_4 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 407.0
HKD1_k127_6116749_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 355.0
HKD1_k127_6116749_6 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 341.0
HKD1_k127_6116749_7 - - - - 0.000000000006677 70.0
HKD1_k127_6150783_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 579.0
HKD1_k127_6150783_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K01784,K03274 - 5.1.3.2,5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 510.0
HKD1_k127_6150783_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 440.0
HKD1_k127_6150783_3 heptosyltransferase K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 376.0
HKD1_k127_6150783_4 PFAM glycosyl transferase family 9 K02841 - - 0.0000000000000000001041 90.0
HKD1_k127_6157081_0 Elongator protein 3, MiaB family, Radical SAM - - - 6.845e-199 627.0
HKD1_k127_6157081_1 COG0346 Lactoylglutathione lyase and related lyases K07032 - - 0.00000000000000000000000000000000000000005569 162.0
HKD1_k127_6157081_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000005935 152.0
HKD1_k127_6157081_3 MarR family - - - 0.00000000000000000000001383 102.0
HKD1_k127_6174018_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 332.0
HKD1_k127_6174018_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 304.0
HKD1_k127_6174018_10 - - - - 0.0000000000000001278 83.0
HKD1_k127_6174018_11 - - - - 0.00002975 49.0
HKD1_k127_6174018_2 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005196 247.0
HKD1_k127_6174018_3 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000001688 243.0
HKD1_k127_6174018_4 - - - - 0.000000000000000000000000000000000000000000000054 171.0
HKD1_k127_6174018_5 DoxX K15977 - - 0.000000000000000000000000000000000000000000006164 167.0
HKD1_k127_6174018_6 - - - - 0.00000000000000000000000000000000000000000008943 167.0
HKD1_k127_6174018_7 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000001078 161.0
HKD1_k127_6174018_8 - - - - 0.00000000000000000000000000000003436 132.0
HKD1_k127_6174018_9 PilZ domain - - - 0.0000000000000000000000004953 108.0
HKD1_k127_61799_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 596.0
HKD1_k127_61799_1 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 421.0
HKD1_k127_61799_2 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 344.0
HKD1_k127_61799_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009025 284.0
HKD1_k127_61799_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000001795 217.0
HKD1_k127_61799_5 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000007795 199.0
HKD1_k127_61799_6 - - - - 0.00000000000000000000000000003093 119.0
HKD1_k127_61799_7 - - - - 0.0000000000000000000008608 106.0
HKD1_k127_61799_9 cyclic nucleotide-binding - - - 0.00001434 48.0
HKD1_k127_6181165_0 Putative diguanylate phosphodiesterase - - - 2.214e-269 847.0
HKD1_k127_6181165_1 His Kinase A (phosphoacceptor) domain K10715 - 2.7.13.3 5.728e-214 694.0
HKD1_k127_6181165_2 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007191 248.0
HKD1_k127_6181165_3 Enoyl-CoA hydratase/isomerase K13816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002493 246.0
HKD1_k127_6181165_4 Bacterial protein of unknown function (DUF898) - - - 0.000000000000000000000000000000000000000000000000000000008351 206.0
HKD1_k127_6181165_5 Enoyl-CoA hydratase K13816 - - 0.0000000005228 66.0
HKD1_k127_6186489_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1344.0
HKD1_k127_6186489_1 LysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 376.0
HKD1_k127_6186489_2 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000004162 206.0
HKD1_k127_6186489_3 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.000000000000000000000000000000000000000000000000292 177.0
HKD1_k127_6189545_0 ABC transporter K06158 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 3.934e-261 819.0
HKD1_k127_6189545_1 Sulfatase-modifying factor enzyme 1 - - - 1.754e-214 678.0
HKD1_k127_6189545_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 505.0
HKD1_k127_6189545_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006346 256.0
HKD1_k127_6189545_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000156 222.0
HKD1_k127_6189545_5 - - - - 0.00000000000000000000000000000000001064 141.0
HKD1_k127_6189545_6 sh3 domain protein K01447,K01448,K09774 - 3.5.1.28 0.0000000000000000000007757 108.0
HKD1_k127_6189545_7 - - - - 0.000000000000001808 78.0
HKD1_k127_6189545_8 - - - - 0.00000000000005592 73.0
HKD1_k127_6197998_0 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 314.0
HKD1_k127_6197998_1 SAF K02279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 309.0
HKD1_k127_6197998_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 297.0
HKD1_k127_6197998_3 Pilus formation protein N terminal region K02280 - - 0.0000000000000000000000000001148 119.0
HKD1_k127_6197998_4 NMT1-like family K02051,K15553 - - 0.0000004643 60.0
HKD1_k127_6199592_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006862 414.0
HKD1_k127_6199592_1 pfkB family carbohydrate kinase K00847,K00856 - 2.7.1.20,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 394.0
HKD1_k127_62057_0 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 357.0
HKD1_k127_62057_1 - - - - 0.000000000001045 74.0
HKD1_k127_62057_2 - - - - 0.000000000004917 72.0
HKD1_k127_62057_3 Cytochrome c554 and c-prime - - - 0.00001996 51.0
HKD1_k127_6207198_0 E1 component K00164 - 1.2.4.2 0.0 1669.0
HKD1_k127_6207198_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1088.0
HKD1_k127_6207198_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 6.605e-233 727.0
HKD1_k127_6207198_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 587.0
HKD1_k127_6207198_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 540.0
HKD1_k127_6207198_5 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 442.0
HKD1_k127_6207198_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 322.0
HKD1_k127_6207198_7 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001126 259.0
HKD1_k127_6207198_8 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000007543 231.0
HKD1_k127_6207198_9 EamA-like transporter family - - - 0.00007901 46.0
HKD1_k127_6207600_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1017.0
HKD1_k127_6207600_1 Acetyl-CoA dehydrogenase C-terminal like K00248,K00249,K20035 - 1.3.8.1,1.3.8.7 9.971e-242 758.0
HKD1_k127_6207600_10 Short-chain dehydrogenase reductase SDR K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 405.0
HKD1_k127_6207600_11 Protein of unknown function (DUF1194) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 357.0
HKD1_k127_6207600_12 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 310.0
HKD1_k127_6207600_13 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005257 277.0
HKD1_k127_6207600_14 PFAM ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000001255 264.0
HKD1_k127_6207600_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003819 246.0
HKD1_k127_6207600_16 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000001855 231.0
HKD1_k127_6207600_17 17 kDa outer membrane surface antigen - - - 0.0000000000000000000000000000000000000001854 156.0
HKD1_k127_6207600_18 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000000000000001437 126.0
HKD1_k127_6207600_19 - - - - 0.000000000000000001319 87.0
HKD1_k127_6207600_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 8.391e-201 632.0
HKD1_k127_6207600_20 - - - - 0.0000007448 53.0
HKD1_k127_6207600_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 538.0
HKD1_k127_6207600_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03215 - 2.1.1.190,2.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 513.0
HKD1_k127_6207600_5 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 488.0
HKD1_k127_6207600_6 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 464.0
HKD1_k127_6207600_7 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 460.0
HKD1_k127_6207600_8 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 423.0
HKD1_k127_6207600_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 409.0
HKD1_k127_6214240_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1154.0
HKD1_k127_6214240_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1069.0
HKD1_k127_6214240_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.107e-219 692.0
HKD1_k127_6214240_3 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 7.323e-215 678.0
HKD1_k127_6214240_4 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009762 601.0
HKD1_k127_6214240_5 Bacterial dnaA protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003915 269.0
HKD1_k127_6214240_6 AI-2E family transporter K03548 - - 0.00000000000000000000000000000000000000000000000000000000000000000001591 235.0
HKD1_k127_6214240_7 Belongs to the pirin family K06911 - - 0.00000000000000000000000002465 108.0
HKD1_k127_6230339_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1250.0
HKD1_k127_6230339_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 584.0
HKD1_k127_6230339_10 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 353.0
HKD1_k127_6230339_11 helix_turn_helix, arabinose operon control protein K18954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 342.0
HKD1_k127_6230339_12 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 318.0
HKD1_k127_6230339_13 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 314.0
HKD1_k127_6230339_14 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004814 271.0
HKD1_k127_6230339_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003895 253.0
HKD1_k127_6230339_16 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001325 246.0
HKD1_k127_6230339_17 Bile acid K03453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002846 253.0
HKD1_k127_6230339_18 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004239 235.0
HKD1_k127_6230339_19 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000002379 200.0
HKD1_k127_6230339_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 563.0
HKD1_k127_6230339_20 Adenylosuccinate lyase C-terminus K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000001911 183.0
HKD1_k127_6230339_21 - - - - 0.00000000000000000000000000000002673 130.0
HKD1_k127_6230339_22 KTSC domain - - - 0.0000000000000001643 81.0
HKD1_k127_6230339_24 - - - - 0.0003029 50.0
HKD1_k127_6230339_3 Belongs to the binding-protein-dependent transport system permease family K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 479.0
HKD1_k127_6230339_4 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 480.0
HKD1_k127_6230339_5 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 458.0
HKD1_k127_6230339_6 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 455.0
HKD1_k127_6230339_7 PFAM ABC transporter K01995,K15783 GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039 3.5.4.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 428.0
HKD1_k127_6230339_8 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 391.0
HKD1_k127_6230339_9 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 383.0
HKD1_k127_6230773_0 Pyridoxal-phosphate dependent enzyme K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 606.0
HKD1_k127_6230773_1 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 464.0
HKD1_k127_6230773_2 Rhodanese Homology Domain K01011 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016782,GO:0016783,GO:0016784,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042262,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 354.0
HKD1_k127_6230773_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 325.0
HKD1_k127_6230773_4 tRNA synthetases class II (A) K07050 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 322.0
HKD1_k127_6230773_5 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 327.0
HKD1_k127_6230773_6 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 311.0
HKD1_k127_6230773_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000003255 126.0
HKD1_k127_6235727_0 Adenylate cyclase - - - 1.263e-246 771.0
HKD1_k127_6235727_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 425.0
HKD1_k127_6235727_2 Tar ligand binding domain homologue K03406,K03776 - - 0.000000000000000000000000000000000000000000000000000000000000003595 226.0
HKD1_k127_6235727_3 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.00000000000000000000000000000000000000000000000000005448 198.0
HKD1_k127_6235727_4 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000001995 111.0
HKD1_k127_6239968_0 Linear amide C-N hydrolases, choloylglycine hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 434.0
HKD1_k127_6239968_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007698 261.0
HKD1_k127_6239968_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000002923 182.0
HKD1_k127_6244475_0 nitrite reductase K15864 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1,1.7.99.1 0.0 1060.0
HKD1_k127_6244475_1 Cytochrome D1 heme domain - - - 7.337e-263 817.0
HKD1_k127_6244475_10 Cytochrome C oxidase, cbb3-type, subunit III K19344 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000002702 107.0
HKD1_k127_6244475_11 FMN_bind K19339,K19343 - - 0.0000000000309 68.0
HKD1_k127_6244475_2 4Fe-4S single cluster domain - - - 2.782e-206 653.0
HKD1_k127_6244475_3 Cytochrome D1 heme domain K19345 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 603.0
HKD1_k127_6244475_4 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 374.0
HKD1_k127_6244475_5 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 336.0
HKD1_k127_6244475_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 299.0
HKD1_k127_6244475_7 transcriptional regulator AsnC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000006081 243.0
HKD1_k127_6244475_8 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000001948 222.0
HKD1_k127_6244475_9 CbiX - - - 0.0000000000000000000000000000000000000000000000005013 184.0
HKD1_k127_6245119_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032,K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 2.096e-282 874.0
HKD1_k127_6245119_1 ABC-type oligopeptide transport system periplasmic component K13893 - - 1.939e-280 871.0
HKD1_k127_6245119_2 Binding-protein-dependent transport system inner membrane component K13894 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 1.511e-200 629.0
HKD1_k127_6245119_3 N-terminal TM domain of oligopeptide transport permease C K13895 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 577.0
HKD1_k127_6283089_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 559.0
HKD1_k127_6283089_1 AFG1-like ATPase K06916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 507.0
HKD1_k127_6283089_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 392.0
HKD1_k127_6283089_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007197 267.0
HKD1_k127_6283089_4 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000008462 238.0
HKD1_k127_6283089_5 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000004041 214.0
HKD1_k127_6284784_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 592.0
HKD1_k127_6284784_1 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 457.0
HKD1_k127_6284784_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 307.0
HKD1_k127_6284784_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000002201 168.0
HKD1_k127_6305903_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 6.614e-199 625.0
HKD1_k127_6305903_1 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 434.0
HKD1_k127_6305903_2 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000149 123.0
HKD1_k127_6310330_0 Taurine catabolism dioxygenase TauD, TfdA family K03119,K22303 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003681 278.0
HKD1_k127_6310330_1 Cold shock K03704 - - 0.00000000000000000000000002374 114.0
HKD1_k127_6310330_2 - - - - 0.0000000000000000000001216 104.0
HKD1_k127_6310330_3 - - - - 0.000000000000000000000682 96.0
HKD1_k127_6323297_0 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007952 452.0
HKD1_k127_6323297_1 transport system small permease component - - - 0.0000000000000000000000000000000000000000000000001183 182.0
HKD1_k127_6323297_2 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000001266 186.0
HKD1_k127_6323297_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000003654 171.0
HKD1_k127_63301_0 Elongation factor G, domain IV K02355 - - 0.0 1054.0
HKD1_k127_63301_1 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 2.018e-217 681.0
HKD1_k127_63301_2 Glucose / Sorbosone dehydrogenase K00117,K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 477.0
HKD1_k127_63301_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 359.0
HKD1_k127_63301_4 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 347.0
HKD1_k127_63301_5 cyclic-guanylate-specific phosphodiesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 338.0
HKD1_k127_63301_6 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008996 248.0
HKD1_k127_63301_7 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000008396 239.0
HKD1_k127_63301_8 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000144 198.0
HKD1_k127_63301_9 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000000000000000000000000000000000000000000001343 174.0
HKD1_k127_6347841_0 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 314.0
HKD1_k127_6347841_1 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004854 271.0
HKD1_k127_6347841_2 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000001114 124.0
HKD1_k127_6356042_0 Histidine kinase K03407 - 2.7.13.3 1.623e-316 993.0
HKD1_k127_6356042_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 463.0
HKD1_k127_6356042_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 394.0
HKD1_k127_6356042_3 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000003061 227.0
HKD1_k127_6356042_4 chemotaxis protein K03408 - - 0.000000000000000000000000000000000000000000000000000000002613 203.0
HKD1_k127_6356042_5 PFAM response regulator receiver K03413 - - 0.000000000000000000000000003458 115.0
HKD1_k127_6379618_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1190.0
HKD1_k127_6379618_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.232e-270 839.0
HKD1_k127_6379618_10 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 364.0
HKD1_k127_6379618_11 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 323.0
HKD1_k127_6379618_12 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004924 251.0
HKD1_k127_6379618_13 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000001035 250.0
HKD1_k127_6379618_14 PFAM NAD-glutamate dehydrogenase K15371 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 0.0000000000000000000000000000000000000000000000000000000002361 209.0
HKD1_k127_6379618_15 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000001174 205.0
HKD1_k127_6379618_16 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000003106 199.0
HKD1_k127_6379618_17 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000002385 203.0
HKD1_k127_6379618_18 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000005972 182.0
HKD1_k127_6379618_19 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000002258 169.0
HKD1_k127_6379618_2 Heparinase II/III-like protein - - - 5.032e-219 695.0
HKD1_k127_6379618_20 protein tyrosine kinase activity - - - 0.00000000000000000000000000000000000001877 154.0
HKD1_k127_6379618_21 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000006186 130.0
HKD1_k127_6379618_22 Protein of unknown function (DUF1761) - - - 0.000000000000000000000000007834 114.0
HKD1_k127_6379618_3 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 610.0
HKD1_k127_6379618_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 595.0
HKD1_k127_6379618_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 508.0
HKD1_k127_6379618_6 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 474.0
HKD1_k127_6379618_7 Major facilitator Superfamily K05939 - 2.3.1.40,6.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 465.0
HKD1_k127_6379618_8 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 456.0
HKD1_k127_6379618_9 Involved in chromosome partitioning - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 400.0
HKD1_k127_6385360_0 Class II Aldolase and Adducin N-terminal domain - - - 3.485e-246 773.0
HKD1_k127_6385360_1 Bacterial SH3 domain - - - 0.000000000686 66.0
HKD1_k127_6386435_0 Leucyl-tRNA synthetase, Domain 2 K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1419.0
HKD1_k127_6386435_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 408.0
HKD1_k127_6386435_10 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000004362 149.0
HKD1_k127_6386435_11 Lytic transglycolase K03642 - - 0.00000000000000000000000000000000000000185 161.0
HKD1_k127_6386435_12 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000003306 136.0
HKD1_k127_6386435_13 - - - - 0.000000000000000000000004983 107.0
HKD1_k127_6386435_14 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000003301 72.0
HKD1_k127_6386435_15 HWE histidine kinase - - - 0.0000000000001647 76.0
HKD1_k127_6386435_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 403.0
HKD1_k127_6386435_3 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 363.0
HKD1_k127_6386435_4 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 334.0
HKD1_k127_6386435_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 326.0
HKD1_k127_6386435_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 326.0
HKD1_k127_6386435_7 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 289.0
HKD1_k127_6386435_8 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005549 250.0
HKD1_k127_6386435_9 Lipopolysaccharide-assembly K03643 - - 0.00000000000000000000000000000000000000000000000000001591 194.0
HKD1_k127_638969_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.775e-201 652.0
HKD1_k127_638969_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 523.0
HKD1_k127_638969_2 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001995 241.0
HKD1_k127_638969_3 Rhodanese-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001315 237.0
HKD1_k127_638969_4 2Fe-2S iron-sulfur cluster binding domain K00256,K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000005377 231.0
HKD1_k127_638969_5 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000000000001496 136.0
HKD1_k127_6417458_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0 1007.0
HKD1_k127_6417458_1 Tripartite tricarboxylate transporter TctA family K07793 - - 8.603e-256 795.0
HKD1_k127_6417458_10 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000001138 226.0
HKD1_k127_6417458_11 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000008375 201.0
HKD1_k127_6417458_12 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000008644 196.0
HKD1_k127_6417458_13 Inner membrane component domain - - - 0.0000000000000000000000000000000000000000000000000006516 186.0
HKD1_k127_6417458_14 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000000000000000000000000000000000000000001762 171.0
HKD1_k127_6417458_15 - - - - 0.0000000000000000000000000000000000001085 150.0
HKD1_k127_6417458_16 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000009395 75.0
HKD1_k127_6417458_2 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 1.468e-214 677.0
HKD1_k127_6417458_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 591.0
HKD1_k127_6417458_4 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 578.0
HKD1_k127_6417458_5 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 576.0
HKD1_k127_6417458_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 477.0
HKD1_k127_6417458_7 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 441.0
HKD1_k127_6417458_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 368.0
HKD1_k127_6417458_9 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000943 290.0
HKD1_k127_6475580_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1194.0
HKD1_k127_6475580_1 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 315.0
HKD1_k127_6475580_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000006333 83.0
HKD1_k127_6484194_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 404.0
HKD1_k127_6484194_1 N-acetylmuramoyl-L-alanine amidase (Family 2) K01447,K03806 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 342.0
HKD1_k127_6484194_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 285.0
HKD1_k127_6484194_3 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000000000000000002195 210.0
HKD1_k127_6484194_4 EamA-like transporter family - - - 0.0000000000000000000000000000006781 126.0
HKD1_k127_6484194_5 - - - - 0.000000000000000001305 90.0
HKD1_k127_6489158_0 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 414.0
HKD1_k127_6489158_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 325.0
HKD1_k127_6489158_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000001214 258.0
HKD1_k127_6489158_3 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000005263 230.0
HKD1_k127_6489158_4 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000005171 209.0
HKD1_k127_6504750_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.654e-267 829.0
HKD1_k127_6504750_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 5.301e-244 764.0
HKD1_k127_6504750_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 512.0
HKD1_k127_6504750_3 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 331.0
HKD1_k127_6504750_4 FAD linked K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 330.0
HKD1_k127_6504750_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000001056 223.0
HKD1_k127_6504750_6 Cytochrome c K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000002796 185.0
HKD1_k127_6504750_7 NIPSNAP - - - 0.0000000000000000000000000534 110.0
HKD1_k127_6514505_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 2.525e-205 641.0
HKD1_k127_6514505_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 547.0
HKD1_k127_6514505_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 424.0
HKD1_k127_6514505_3 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 370.0
HKD1_k127_6514505_4 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 376.0
HKD1_k127_6514505_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 366.0
HKD1_k127_6514505_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004944 267.0
HKD1_k127_6514505_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000007467 205.0
HKD1_k127_6514505_8 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000001354 124.0
HKD1_k127_6514505_9 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000009528 124.0
HKD1_k127_6524907_0 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 1.499e-264 824.0
HKD1_k127_6524907_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 505.0
HKD1_k127_6524907_2 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000001489 239.0
HKD1_k127_6524907_3 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000004463 224.0
HKD1_k127_6524907_4 Copper resistance protein D K07245 - - 0.000000000000000000000000003023 123.0
HKD1_k127_6524907_5 Protein of unknown function (DUF1467) - - - 0.00000000000000000000002474 104.0
HKD1_k127_6531925_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 603.0
HKD1_k127_6531925_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 582.0
HKD1_k127_6531925_2 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 377.0
HKD1_k127_6531925_3 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 291.0
HKD1_k127_6531925_4 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002808 284.0
HKD1_k127_6531925_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000001755 164.0
HKD1_k127_6531925_6 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000018 129.0
HKD1_k127_6531925_7 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000007527 71.0
HKD1_k127_6531925_8 Class II Aldolase and Adducin N-terminal domain - - - 0.0000002234 52.0
HKD1_k127_65996_0 NAD-dependent epimerase dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 305.0
HKD1_k127_65996_1 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000002449 205.0
HKD1_k127_6617300_0 Proton-conducting membrane transporter K12141 - - 1.571e-240 747.0
HKD1_k127_6617300_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 1.929e-233 731.0
HKD1_k127_6617300_2 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 329.0
HKD1_k127_6617300_3 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 295.0
HKD1_k127_6617300_4 PilZ domain - - - 0.000000000005269 70.0
HKD1_k127_6617300_5 - - - - 0.0002089 49.0
HKD1_k127_6621092_0 Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 463.0
HKD1_k127_6621092_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 361.0
HKD1_k127_6621092_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 331.0
HKD1_k127_6621092_3 Sporulation related domain - - - 0.0000000000000000000000000000000000000000000000000000000001586 221.0
HKD1_k127_6621092_4 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000007301 104.0
HKD1_k127_6621092_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.000000000000000000008191 94.0
HKD1_k127_6621092_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.00000000000007755 71.0
HKD1_k127_6646669_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.907e-321 987.0
HKD1_k127_6646669_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 5.169e-226 706.0
HKD1_k127_6646669_10 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000002883 139.0
HKD1_k127_6646669_11 Septum formation initiator - - - 0.000000000000000000000000000004653 122.0
HKD1_k127_6646669_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 546.0
HKD1_k127_6646669_3 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 440.0
HKD1_k127_6646669_4 Methyltransferase fkbm family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 408.0
HKD1_k127_6646669_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 389.0
HKD1_k127_6646669_6 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 351.0
HKD1_k127_6646669_7 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000005933 263.0
HKD1_k127_6646669_8 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005193 266.0
HKD1_k127_6646669_9 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000018 202.0
HKD1_k127_6656866_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1063.0
HKD1_k127_6656866_1 Sigma-54 interaction domain K10943 - - 4.955e-231 721.0
HKD1_k127_6656866_10 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000005932 169.0
HKD1_k127_6656866_11 Protein of unknown function (DUF952) - - - 0.000000000000000000000000000000000000000000004629 165.0
HKD1_k127_6656866_12 Anti-sigma-K factor rskA - - - 0.000000000000000000000000000000000000005654 155.0
HKD1_k127_6656866_13 Flagellar hook-length control protein FliK K10565 - - 0.00000000000000000000000000000000008697 150.0
HKD1_k127_6656866_14 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000002487 133.0
HKD1_k127_6656866_15 Helix-turn-helix domain - - - 0.0000000000000000000000000000006457 123.0
HKD1_k127_6656866_16 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000001606 125.0
HKD1_k127_6656866_17 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000004955 111.0
HKD1_k127_6656866_18 - - - - 0.00000001133 61.0
HKD1_k127_6656866_2 The M ring may be actively involved in energy transduction K02409 - - 6.6e-227 715.0
HKD1_k127_6656866_3 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 603.0
HKD1_k127_6656866_4 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 568.0
HKD1_k127_6656866_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 434.0
HKD1_k127_6656866_6 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003692 251.0
HKD1_k127_6656866_7 RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000007883 201.0
HKD1_k127_6656866_8 Flagellar biosynthesis type III secretory pathway protein K02411 - - 0.000000000000000000000000000000000000000000000000003005 188.0
HKD1_k127_6656866_9 Protein of unknown function (DUF1153) - - - 0.00000000000000000000000000000000000000000000000001794 180.0
HKD1_k127_6670062_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00410,K00412 - - 8.031e-223 700.0
HKD1_k127_6670062_1 ATPase family associated with various cellular activities (AAA) K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 554.0
HKD1_k127_6670062_10 Protein of unknown function (DUF1285) K09986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009762 265.0
HKD1_k127_6670062_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004007 268.0
HKD1_k127_6670062_12 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000002911 215.0
HKD1_k127_6670062_13 - - - - 0.000000000000000000000000003726 113.0
HKD1_k127_6670062_2 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 539.0
HKD1_k127_6670062_3 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 496.0
HKD1_k127_6670062_4 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 464.0
HKD1_k127_6670062_5 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 442.0
HKD1_k127_6670062_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00410,K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 386.0
HKD1_k127_6670062_7 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 337.0
HKD1_k127_6670062_8 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 301.0
HKD1_k127_6670062_9 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006391 276.0
HKD1_k127_6710272_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 5.319e-229 715.0
HKD1_k127_6710272_1 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 1.019e-214 676.0
HKD1_k127_6710272_2 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 506.0
HKD1_k127_6710272_3 Histidyl-tRNA synthetase K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 478.0
HKD1_k127_6710272_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 344.0
HKD1_k127_6710272_5 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 325.0
HKD1_k127_6710272_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 286.0
HKD1_k127_6710272_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000001807 187.0
HKD1_k127_6710272_8 SnoaL-like domain - - - 0.0000000000000000004765 93.0
HKD1_k127_6710272_9 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.000001783 52.0
HKD1_k127_6764551_0 GlcNAc-PI de-N-acetylase K16515 - 4.2.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 478.0
HKD1_k127_6764551_1 Aldolase/RraA K02553,K10218 - 4.1.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 366.0
HKD1_k127_6764551_2 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000005853 229.0
HKD1_k127_6764551_3 - - - - 0.0000000000000000000000000000000000000000000000002283 181.0
HKD1_k127_6764551_4 4,5-dihydroxyphthalate decarboxylase - - - 0.00000000000000007637 82.0
HKD1_k127_6764551_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00000000000001091 85.0
HKD1_k127_6764551_6 Flp/Fap pilin component K02651 - - 0.0000000000001616 72.0
HKD1_k127_6764551_7 Flp/Fap pilin component K02651 - - 0.00000000000122 69.0
HKD1_k127_6819295_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 6.34e-296 927.0
HKD1_k127_6819295_1 TRAP transporter solute receptor TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 462.0
HKD1_k127_6819295_2 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 377.0
HKD1_k127_6819295_3 AAA domain, putative AbiEii toxin, Type IV TA system K02074,K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 359.0
HKD1_k127_6819295_4 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 318.0
HKD1_k127_6819295_5 Predicted permease - - - 0.00000000000000000000000000000000000000000000000000002167 193.0
HKD1_k127_6819295_6 Predicted permease - - - 0.0000000000000000000000000000000000000000000000004168 188.0
HKD1_k127_6819295_7 CrcB-like protein, Camphor Resistance (CrcB) K06199 - - 0.0000000000000000000000000000000000001872 143.0
HKD1_k127_6819295_8 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.000000000000000003471 87.0
HKD1_k127_6819295_9 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.000000000002569 69.0
HKD1_k127_6823305_0 Oligopeptidase F K08602 - - 4.382e-304 942.0
HKD1_k127_6823305_1 Sigma-54 interaction domain K10912 GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 9.598e-217 683.0
HKD1_k127_6823305_2 ABC1 family - - - 3.706e-215 675.0
HKD1_k127_6823305_3 Alanine dehydrogenase/PNT, C-terminal domain K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 580.0
HKD1_k127_6823305_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 439.0
HKD1_k127_6823305_5 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 411.0
HKD1_k127_6823305_6 Bacterial aa3 type cytochrome c oxidase subunit IV - - - 0.000000004419 62.0
HKD1_k127_6949702_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 3.155e-205 650.0
HKD1_k127_6949702_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 457.0
HKD1_k127_6949702_2 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 405.0
HKD1_k127_7067787_0 Fumarate reductase flavoprotein C-term - - - 3.132e-222 702.0
HKD1_k127_7067787_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 617.0
HKD1_k127_7067787_2 PFAM Acetamidase Formamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 475.0
HKD1_k127_7067787_3 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008323 435.0
HKD1_k127_7067787_4 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 325.0
HKD1_k127_7067787_5 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006475 263.0
HKD1_k127_7067787_6 membrane K08988 - - 0.000000000000000000000000000000000000000000000000000000001462 210.0
HKD1_k127_7067787_7 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000005161 164.0
HKD1_k127_7067787_8 pfkB family carbohydrate kinase K16370 - 2.7.1.11 0.00001756 47.0
HKD1_k127_7077927_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.901e-299 935.0
HKD1_k127_7077927_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.261e-294 924.0
HKD1_k127_7077927_10 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000002939 215.0
HKD1_k127_7077927_11 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000000000000000000000000000000000000000004224 202.0
HKD1_k127_7077927_2 FAD dependent oxidoreductase - - - 1.22e-204 649.0
HKD1_k127_7077927_3 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 373.0
HKD1_k127_7077927_4 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 375.0
HKD1_k127_7077927_5 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 343.0
HKD1_k127_7077927_6 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 302.0
HKD1_k127_7077927_7 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001048 286.0
HKD1_k127_7077927_8 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002419 259.0
HKD1_k127_7077927_9 Domain of unknown function (DUF1932) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001128 259.0
HKD1_k127_7079948_0 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 311.0
HKD1_k127_7079948_1 Membrane-associated sensor, integral membrane domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000074 263.0
HKD1_k127_7079948_2 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.0000000000000000000000000003239 115.0
HKD1_k127_7084391_0 Belongs to the GARS family K01945 - 6.3.4.13 3.074e-204 642.0
HKD1_k127_7084391_1 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 1.247e-195 621.0
HKD1_k127_7084391_10 - - - - 0.0000000000000000000000000000000000000007126 154.0
HKD1_k127_7084391_11 Domain of unknown function (DUF4170) - - - 0.0000000000000000000000000000000001252 134.0
HKD1_k127_7084391_12 Uncharacterized protein conserved in bacteria (DUF2093) - - - 0.000000000000000000000000003035 112.0
HKD1_k127_7084391_13 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.00000000000000000000000009493 107.0
HKD1_k127_7084391_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 610.0
HKD1_k127_7084391_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 501.0
HKD1_k127_7084391_4 Alpha beta hydrolase K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 449.0
HKD1_k127_7084391_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 362.0
HKD1_k127_7084391_6 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 310.0
HKD1_k127_7084391_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 293.0
HKD1_k127_7084391_8 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000409 248.0
HKD1_k127_7084391_9 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000000000000000000000000000001341 244.0
HKD1_k127_7091916_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 3.377e-296 923.0
HKD1_k127_7091916_1 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.0000000000000000000000000000000000000001413 154.0
HKD1_k127_7091916_2 DedA family - - - 0.000000000000000000000000002702 112.0
HKD1_k127_7105054_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.713e-304 943.0
HKD1_k127_7105054_1 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 3.639e-229 718.0
HKD1_k127_7105054_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 497.0
HKD1_k127_7105054_3 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 408.0
HKD1_k127_7105054_4 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 376.0
HKD1_k127_7105054_5 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000001033 233.0
HKD1_k127_7114270_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 450.0
HKD1_k127_7114270_1 Domain of unknown function (DUF4070) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 343.0
HKD1_k127_7114270_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004983 285.0
HKD1_k127_7114270_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009183 254.0
HKD1_k127_7114270_4 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000002415 214.0
HKD1_k127_7114270_5 aspartyl Asparaginyl beta-hydroxylase K12979 - - 0.0000000000000000000000000000000000000000000000000000000007022 213.0
HKD1_k127_7114270_6 Flp/Fap pilin component K02651 - - 0.00000000001444 67.0
HKD1_k127_71221_0 Binding-protein-dependent transport system inner membrane component K02011 - - 4.551e-200 633.0
HKD1_k127_71221_1 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 533.0
HKD1_k127_71221_2 TOBE domain K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 529.0
HKD1_k127_7125121_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 1475.0
HKD1_k127_7132301_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 420.0
HKD1_k127_7132301_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 374.0
HKD1_k127_7132301_2 HAD-hyrolase-like K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 330.0
HKD1_k127_7137951_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 2.045e-272 842.0
HKD1_k127_7137951_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.229e-265 826.0
HKD1_k127_7137951_2 Histidine kinase K14980 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 1.621e-259 812.0
HKD1_k127_7137951_3 Transcriptional regulatory protein, C terminal K14981 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008902 445.0
HKD1_k127_7137951_4 LTXXQ motif family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 355.0
HKD1_k127_7137951_5 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000164 287.0
HKD1_k127_7137951_6 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002929 272.0
HKD1_k127_7137951_7 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000000000000000000000000000000000002461 224.0
HKD1_k127_7137951_8 HPr Serine kinase C-terminal domain K06023 - - 0.0000000000000000000000000000000000007001 145.0
HKD1_k127_7137951_9 system phosphocarrier protein HPr K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0044424,GO:0044464,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702 - 0.000000000000000000000000001068 118.0
HKD1_k127_7152443_0 Male sterility protein K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 489.0
HKD1_k127_7152443_1 Pfam Transposase IS66 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 423.0
HKD1_k127_7152443_10 YHS domain protein - - - 0.00000000000000000000000000000000000000000000004596 175.0
HKD1_k127_7152443_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 295.0
HKD1_k127_7152443_3 Protein of unknown function (DUF1134) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 291.0
HKD1_k127_7152443_4 Histidine phosphotransferase C-terminal domain K13588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002286 281.0
HKD1_k127_7152443_5 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001152 257.0
HKD1_k127_7152443_6 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000001318 261.0
HKD1_k127_7152443_7 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004378 234.0
HKD1_k127_7152443_8 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000000000000000000000000000003379 204.0
HKD1_k127_7152443_9 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000006766 179.0
HKD1_k127_7158372_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 547.0
HKD1_k127_7158372_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 535.0
HKD1_k127_7158372_10 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000001318 181.0
HKD1_k127_7158372_11 Metallopeptidase family M24 - - - 0.0000000000002424 82.0
HKD1_k127_7158372_2 Amidohydrolase K10221 - 3.1.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 424.0
HKD1_k127_7158372_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 308.0
HKD1_k127_7158372_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K09565 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 285.0
HKD1_k127_7158372_5 Ankyrin repeats (3 copies) K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 258.0
HKD1_k127_7158372_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001412 262.0
HKD1_k127_7158372_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002565 252.0
HKD1_k127_7158372_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005062 255.0
HKD1_k127_7158372_9 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000613 218.0
HKD1_k127_7169751_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1073.0
HKD1_k127_7169751_1 Protein conserved in bacteria K09989 - - 3.815e-213 666.0
HKD1_k127_7169751_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 431.0
HKD1_k127_7169751_3 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000001379 256.0
HKD1_k127_7169751_4 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000003648 238.0
HKD1_k127_7169751_5 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000008773 199.0
HKD1_k127_7169751_6 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000003315 98.0
HKD1_k127_7169751_7 - - - - 0.0000000000000001098 82.0
HKD1_k127_7169751_8 Phage-related minor tail protein K18642 - - 0.00000000000005612 85.0
HKD1_k127_7178506_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 592.0
HKD1_k127_7178506_1 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 398.0
HKD1_k127_7178506_2 phosphatidylethanolamine N-methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 312.0
HKD1_k127_7178506_3 - - - - 0.000000000000000005171 89.0
HKD1_k127_7184580_0 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 6.155e-204 648.0
HKD1_k127_7184580_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 459.0
HKD1_k127_7184580_2 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003898 284.0
HKD1_k127_7184580_3 Major facilitator Superfamily K07165,K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008601 274.0
HKD1_k127_7188354_0 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 594.0
HKD1_k127_7188354_1 Belongs to the TPP enzyme family K01577,K01652 - 2.2.1.6,4.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 317.0
HKD1_k127_7201987_0 TIGRFAM cytochrome c oxidase, cbb3-type, subunit I K00404 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 3.761e-320 984.0
HKD1_k127_7201987_1 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 425.0
HKD1_k127_7201987_2 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 408.0
HKD1_k127_7201987_3 4Fe-4S ferredoxin, iron-sulfur binding domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000001305 222.0
HKD1_k127_7201987_4 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.00000000000000272 81.0
HKD1_k127_7219187_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 366.0
HKD1_k127_7219187_1 COG0006 Xaa-Pro aminopeptidase K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000215 126.0
HKD1_k127_7234511_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 437.0
HKD1_k127_7234511_1 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 325.0
HKD1_k127_7234511_2 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002089 274.0
HKD1_k127_7234511_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000002587 158.0
HKD1_k127_7234511_4 HNH endonuclease - - - 0.000000001557 60.0
HKD1_k127_7242142_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 438.0
HKD1_k127_7242142_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000001885 183.0
HKD1_k127_7242142_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000001046 157.0
HKD1_k127_7242142_3 Heavy-metal resistance - - - 0.000000000000388 79.0
HKD1_k127_7242142_4 - - - - 0.0004888 47.0
HKD1_k127_7246145_0 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 611.0
HKD1_k127_7246145_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009357 565.0
HKD1_k127_7254356_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 371.0
HKD1_k127_7254356_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 344.0
HKD1_k127_7254356_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 334.0
HKD1_k127_7254356_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000004964 192.0
HKD1_k127_7254356_4 Enoyl-(Acyl carrier protein) reductase K00059,K19550 - 1.1.1.100 0.000000000000000000000000000000000000000000000000001087 192.0
HKD1_k127_7254356_5 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000007142 170.0
HKD1_k127_7254356_6 helix_turn_helix multiple antibiotic resistance protein K22296 - - 0.000000000000000000000000000000000000000000001307 169.0
HKD1_k127_7254356_7 Enoyl-(Acyl carrier protein) reductase K00059,K19550 - 1.1.1.100 0.0000000000000000000000000000000000000000544 161.0
HKD1_k127_7267112_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 391.0
HKD1_k127_7267112_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 378.0
HKD1_k127_7267112_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 363.0
HKD1_k127_7267112_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 309.0
HKD1_k127_7267112_4 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003642 276.0
HKD1_k127_7267112_5 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000002427 242.0
HKD1_k127_7267112_6 - - - - 0.000000000000000009693 87.0
HKD1_k127_7270697_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 1.536e-295 917.0
HKD1_k127_7270697_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 469.0
HKD1_k127_7270697_2 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 454.0
HKD1_k127_7270697_3 Cytidylyltransferase K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 312.0
HKD1_k127_7270697_4 Cytochrome c K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001866 263.0
HKD1_k127_7270697_5 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000373 235.0
HKD1_k127_7270697_6 methyl-accepting chemotaxis protein - - - 0.00000000000000000000000000000000000000000000000000000000001514 223.0
HKD1_k127_7270697_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.000000000001279 74.0
HKD1_k127_7276164_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 380.0
HKD1_k127_7276164_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 348.0
HKD1_k127_7276164_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000003237 172.0
HKD1_k127_7276164_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000001453 146.0
HKD1_k127_7276164_4 Protein of unknown function (DUF465) - - - 0.0000000000000000000022 96.0
HKD1_k127_7276164_5 Protein of unknown function (DUF465) - - - 0.000000000000002817 80.0
HKD1_k127_7304016_0 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 541.0
HKD1_k127_7304016_1 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004411 263.0
HKD1_k127_7304016_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000002196 209.0
HKD1_k127_7308693_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 541.0
HKD1_k127_7308693_1 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 532.0
HKD1_k127_7308693_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007105 286.0
HKD1_k127_7308693_3 Methyltransferase small domain K15460 - 2.1.1.223 0.0000000000000000000000000000000000001198 147.0
HKD1_k127_7308693_4 Putative prokaryotic signal transducing protein - - - 0.0000000000000000000000019 105.0
HKD1_k127_7312992_0 Carboxyl transferase domain K01966 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 1.106e-270 836.0
HKD1_k127_7312992_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 362.0
HKD1_k127_7312992_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000111 192.0
HKD1_k127_7312992_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000004972 168.0
HKD1_k127_7316846_0 Transporter associated domain K11105 - - 2.032e-230 727.0
HKD1_k127_7316846_1 Aminotransferase class I and II - - - 1.029e-212 666.0
HKD1_k127_7316846_10 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001888 277.0
HKD1_k127_7316846_11 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000001004 244.0
HKD1_k127_7316846_12 ABC-type molybdate transport system, permease component K02018 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000001831 217.0
HKD1_k127_7316846_13 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000002753 211.0
HKD1_k127_7316846_14 - - - - 0.000000000000000000000000000001094 128.0
HKD1_k127_7316846_15 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000001795 109.0
HKD1_k127_7316846_2 acyl-CoA dehydrogenase - - - 8.002e-210 658.0
HKD1_k127_7316846_3 PFAM Prokaryotic protein of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 530.0
HKD1_k127_7316846_4 COG0451 Nucleoside-diphosphate-sugar epimerases K22025 - 1.1.1.410 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 478.0
HKD1_k127_7316846_5 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 472.0
HKD1_k127_7316846_6 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 457.0
HKD1_k127_7316846_7 periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 366.0
HKD1_k127_7316846_8 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 344.0
HKD1_k127_7316846_9 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 300.0
HKD1_k127_7322897_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.286e-221 693.0
HKD1_k127_7322897_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 2.168e-219 692.0
HKD1_k127_7322897_10 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000004399 266.0
HKD1_k127_7322897_11 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000002464 229.0
HKD1_k127_7322897_12 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000523 214.0
HKD1_k127_7322897_13 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000002686 199.0
HKD1_k127_7322897_14 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000003203 198.0
HKD1_k127_7322897_15 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000494 181.0
HKD1_k127_7322897_16 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000004131 165.0
HKD1_k127_7322897_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 589.0
HKD1_k127_7322897_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 595.0
HKD1_k127_7322897_4 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 538.0
HKD1_k127_7322897_5 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 424.0
HKD1_k127_7322897_6 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 308.0
HKD1_k127_7322897_7 Scaffold protein Nfu/NifU N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 298.0
HKD1_k127_7322897_8 Glycoprotease family K01409,K14742 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 293.0
HKD1_k127_7322897_9 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006765 282.0
HKD1_k127_7338516_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 502.0
HKD1_k127_7338516_1 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 456.0
HKD1_k127_7338516_2 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000147 172.0
HKD1_k127_7358086_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1193.0
HKD1_k127_7358086_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 308.0
HKD1_k127_7358802_0 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 432.0
HKD1_k127_7358802_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000001162 222.0
HKD1_k127_7359144_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.689e-313 981.0
HKD1_k127_7359144_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 393.0
HKD1_k127_7359144_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 354.0
HKD1_k127_7359144_3 Sugar (and other) transporter K08369 - - 0.0000000000000001073 85.0
HKD1_k127_7366525_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1072.0
HKD1_k127_7366525_1 Protein of unknown function - - - 0.0 1066.0
HKD1_k127_7366525_10 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 503.0
HKD1_k127_7366525_11 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 440.0
HKD1_k127_7366525_12 Diguanylate cyclase K13590 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 426.0
HKD1_k127_7366525_13 Aminotransferase class-V K04487 GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 415.0
HKD1_k127_7366525_14 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 398.0
HKD1_k127_7366525_15 ATPases associated with a variety of cellular activities K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 384.0
HKD1_k127_7366525_16 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001433 260.0
HKD1_k127_7366525_17 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000001175 223.0
HKD1_k127_7366525_18 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000001146 196.0
HKD1_k127_7366525_19 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000001359 196.0
HKD1_k127_7366525_2 Uncharacterized protein family (UPF0051) K09014 - - 1.628e-285 881.0
HKD1_k127_7366525_20 Pfam:DUF59 - - - 0.000000000000000000000000000000000000000000000000002556 185.0
HKD1_k127_7366525_21 methyltransferase activity - - - 0.0000000000000000000000000000000000000009615 153.0
HKD1_k127_7366525_22 COG2940 Proteins containing SET domain K07117 - - 0.000000000000000000007085 99.0
HKD1_k127_7366525_24 - - - - 0.00000001226 63.0
HKD1_k127_7366525_3 Cys/Met metabolism PLP-dependent enzyme K11717 - 2.8.1.7,4.4.1.16 6.458e-221 690.0
HKD1_k127_7366525_4 C4-dicarboxylate ABC transporter permease - - - 1.727e-211 665.0
HKD1_k127_7366525_5 Belongs to the DEAD box helicase family K03732,K11927 - 3.6.4.13 4.306e-194 614.0
HKD1_k127_7366525_6 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 595.0
HKD1_k127_7366525_7 amino acid peptide transporter K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 584.0
HKD1_k127_7366525_8 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 552.0
HKD1_k127_7366525_9 4-hydroxybenzoate K00481 - 1.14.13.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 506.0
HKD1_k127_7376367_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.811e-248 771.0
HKD1_k127_7376367_1 ABC transporter K02471 - - 2.49e-242 760.0
HKD1_k127_7376367_2 Bacterial extracellular solute-binding protein, family 7 - - - 4.587e-205 641.0
HKD1_k127_7376367_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 531.0
HKD1_k127_7376367_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000004112 126.0
HKD1_k127_7378353_0 Adenylate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 430.0
HKD1_k127_7388790_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 376.0
HKD1_k127_7388790_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 306.0
HKD1_k127_7388790_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000002383 136.0
HKD1_k127_7388790_3 PilZ domain - - - 0.000000000000000002757 88.0
HKD1_k127_740360_0 Esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000006146 183.0
HKD1_k127_740360_1 - - - - 0.0001581 52.0
HKD1_k127_7405568_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 610.0
HKD1_k127_7405568_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 312.0
HKD1_k127_7405568_2 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 304.0
HKD1_k127_7405568_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009722 244.0
HKD1_k127_7405568_4 CHASE2 - - - 0.00000000000000000000000000000000000000001383 156.0
HKD1_k127_7405568_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000007795 81.0
HKD1_k127_7446733_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 517.0
HKD1_k127_7446733_1 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000003514 166.0
HKD1_k127_7446733_2 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000001937 64.0
HKD1_k127_7451766_0 Domain of unknown function (DUF4175) - - - 3.391e-291 917.0
HKD1_k127_7451766_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 6.09e-205 647.0
HKD1_k127_7451766_2 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 482.0
HKD1_k127_7451766_3 ATPases associated with a variety of cellular activities K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 401.0
HKD1_k127_7451766_4 Uncharacterized protein conserved in bacteria (DUF2125) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 366.0
HKD1_k127_7451766_5 Cell division protein K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 327.0
HKD1_k127_7451766_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 295.0
HKD1_k127_7451766_7 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000000000000000000000000000000002266 246.0
HKD1_k127_7451766_8 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000004145 211.0
HKD1_k127_7451766_9 TIGRFAM MJ0042 family finger-like protein - - - 0.00000000000000000000000000000000000000000000001206 184.0
HKD1_k127_7456390_0 His Kinase A (phosphoacceptor) domain K07716 - 2.7.13.3 2.651e-210 662.0
HKD1_k127_7456390_1 Aspartyl protease K06985 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002755 250.0
HKD1_k127_7456390_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000522 121.0
HKD1_k127_7456390_3 Protein of unknown function (DUF1289) K06938 - - 0.0000000000003104 71.0
HKD1_k127_7476167_0 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 477.0
HKD1_k127_7476167_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 407.0
HKD1_k127_7476167_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 369.0
HKD1_k127_7476167_3 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005261 264.0
HKD1_k127_7476167_4 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.0000000000000000000000000000000000003975 154.0
HKD1_k127_7493530_0 Lactonase, 7-bladed beta-propeller K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 448.0
HKD1_k127_7493530_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 384.0
HKD1_k127_7493530_2 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000164 287.0
HKD1_k127_7493530_3 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001746 286.0
HKD1_k127_7493530_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003301 259.0
HKD1_k127_7493530_5 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000006129 236.0
HKD1_k127_7493530_6 Belongs to the bacterial histone-like protein family - - - 0.00000000000000000000000000000000001242 138.0
HKD1_k127_7493530_7 Belongs to the bacterial histone-like protein family K03530 - - 0.00000000000000000000000000000003799 127.0
HKD1_k127_7493530_8 - - - - 0.00001094 49.0
HKD1_k127_749693_0 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 503.0
HKD1_k127_749693_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000237 161.0
HKD1_k127_749693_2 Cytochrome c - - - 0.0000000000000000006188 91.0
HKD1_k127_7502292_0 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 433.0
HKD1_k127_7502292_1 Transcriptional regulatory protein, C terminal K07657 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 406.0
HKD1_k127_7502292_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 386.0
HKD1_k127_7502292_3 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 362.0
HKD1_k127_7502292_4 GcrA cell cycle regulator K13583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000344 237.0
HKD1_k127_7588118_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1023.0
HKD1_k127_7588118_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 3.964e-227 708.0
HKD1_k127_7588118_10 Domain of unknown function (DUF1732) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 398.0
HKD1_k127_7588118_11 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 378.0
HKD1_k127_7588118_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 304.0
HKD1_k127_7588118_13 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001024 284.0
HKD1_k127_7588118_14 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003998 269.0
HKD1_k127_7588118_15 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000001241 245.0
HKD1_k127_7588118_16 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000009917 199.0
HKD1_k127_7588118_17 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000002234 185.0
HKD1_k127_7588118_18 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000001236 151.0
HKD1_k127_7588118_19 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000009529 148.0
HKD1_k127_7588118_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.1 3.152e-225 709.0
HKD1_k127_7588118_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 512.0
HKD1_k127_7588118_4 Permease K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 455.0
HKD1_k127_7588118_5 Acyl transferase domain K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 448.0
HKD1_k127_7588118_6 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 436.0
HKD1_k127_7588118_7 Permease K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 431.0
HKD1_k127_7588118_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009699 413.0
HKD1_k127_7588118_9 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 406.0
HKD1_k127_7601819_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 3.594e-274 855.0
HKD1_k127_7601819_1 acyl-CoA dehydrogenase K09456 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008470,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016491,GO:0016627,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0033554,GO:0042802,GO:0043565,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 8.789e-236 740.0
HKD1_k127_7601819_10 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002443 269.0
HKD1_k127_7601819_11 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000006915 235.0
HKD1_k127_7601819_12 Protein of unknown function (DUF2892) - - - 0.000000000000000000000000000000000000000000000000000000000000003747 223.0
HKD1_k127_7601819_13 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000003594 205.0
HKD1_k127_7601819_14 MAPEG family - - - 0.000000000000000000000000000000000000000000000000000000019 200.0
HKD1_k127_7601819_15 helix_turn_helix, Arsenical Resistance Operon Repressor K22042 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000002957 140.0
HKD1_k127_7601819_16 - - - - 0.00000001917 61.0
HKD1_k127_7601819_2 Aminotransferase class I and II K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 1.154e-226 706.0
HKD1_k127_7601819_3 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 609.0
HKD1_k127_7601819_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 583.0
HKD1_k127_7601819_5 lactate metabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007388 563.0
HKD1_k127_7601819_6 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446,K11532 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 530.0
HKD1_k127_7601819_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 453.0
HKD1_k127_7601819_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 368.0
HKD1_k127_7601819_9 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 321.0
HKD1_k127_7603899_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 566.0
HKD1_k127_7603899_1 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 458.0
HKD1_k127_7603899_2 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 364.0
HKD1_k127_7603899_3 Protein of unknown function (DUF1036) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 367.0
HKD1_k127_7603899_4 COG2370 Hydrogenase urease accessory protein K03192 - - 0.00000000000000000000000000000000000001735 157.0
HKD1_k127_7603899_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000004846 59.0
HKD1_k127_7738066_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 302.0
HKD1_k127_7738066_1 Phasin protein - - - 0.000000000000000000000000000000000008683 141.0
HKD1_k127_7738066_2 Putative peptidoglycan binding domain K21470 - - 0.000000000000000000000000000001479 125.0
HKD1_k127_7783437_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 6.503e-265 820.0
HKD1_k127_7783437_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 3.185e-198 622.0
HKD1_k127_7783437_10 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 291.0
HKD1_k127_7783437_11 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000001802 260.0
HKD1_k127_7783437_12 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005198 257.0
HKD1_k127_7783437_13 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000005983 214.0
HKD1_k127_7783437_14 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000346 212.0
HKD1_k127_7783437_15 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000003126 213.0
HKD1_k127_7783437_16 Bacterial transcription activator, effector binding domain - - - 0.00000000000000000000000000000000000000000000000000000000007222 215.0
HKD1_k127_7783437_17 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002613 203.0
HKD1_k127_7783437_18 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000009825 177.0
HKD1_k127_7783437_19 - - - - 0.000000000000000000000000000000000000000001436 166.0
HKD1_k127_7783437_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 591.0
HKD1_k127_7783437_20 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000002341 143.0
HKD1_k127_7783437_21 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.000000000000000000000000000000109 134.0
HKD1_k127_7783437_22 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000003837 103.0
HKD1_k127_7783437_23 BFD domain protein 2Fe-2S -binding domain protein - - - 0.0000000000000000000174 93.0
HKD1_k127_7783437_24 Pyridoxamine 5'-phosphate K07006 - - 0.0000000000000001071 81.0
HKD1_k127_7783437_25 - - - - 0.0000000894 63.0
HKD1_k127_7783437_26 - - - - 0.00007233 49.0
HKD1_k127_7783437_3 MiaB-like tRNA modifying enzyme K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006028 574.0
HKD1_k127_7783437_4 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 479.0
HKD1_k127_7783437_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 461.0
HKD1_k127_7783437_6 HpcH/HpaI aldolase/citrate lyase family K01644,K14451 - 3.1.2.30,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 422.0
HKD1_k127_7783437_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 374.0
HKD1_k127_7783437_8 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 332.0
HKD1_k127_7783437_9 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 321.0
HKD1_k127_783102_0 Dehydratase family K01687 - 4.2.1.9 1.379e-284 895.0
HKD1_k127_783102_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 335.0
HKD1_k127_7876385_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 302.0
HKD1_k127_7876385_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 299.0
HKD1_k127_7876385_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000012 256.0
HKD1_k127_7876385_3 Dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.00000000000000000000000002411 116.0
HKD1_k127_7876385_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01856,K01860,K19802 - 5.1.1.20,5.5.1.1,5.5.1.7 0.00000000000000000008609 94.0
HKD1_k127_78851_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 304.0
HKD1_k127_78851_1 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002702 264.0
HKD1_k127_78851_2 Methyltransferase - - - 0.000000000000000000000000000000000001803 141.0
HKD1_k127_78851_3 2-keto-4-pentenoate hydratase - - - 0.0000000000000000000000000000007587 125.0
HKD1_k127_78851_4 - - - - 0.00000000004262 71.0
HKD1_k127_7898419_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 373.0
HKD1_k127_7898419_1 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000001085 234.0
HKD1_k127_7965969_0 Amidohydrolase family K01466 - 3.5.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 446.0
HKD1_k127_7965969_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 365.0
HKD1_k127_7965969_2 COG2513 PEP phosphonomutase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003145 259.0
HKD1_k127_8033944_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 606.0
HKD1_k127_8033944_1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 586.0
HKD1_k127_8033944_2 OpgC protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 516.0
HKD1_k127_8033944_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 482.0
HKD1_k127_8033944_4 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 466.0
HKD1_k127_8033944_5 PFAM lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006278 246.0
HKD1_k127_8033944_6 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000002669 232.0
HKD1_k127_8033944_7 TIGRFAM acetylornithine and succinylornithine aminotransferase K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000004009 217.0
HKD1_k127_8033944_8 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000000000001093 192.0
HKD1_k127_8033944_9 Sulfatase - - - 0.0000000001803 62.0
HKD1_k127_809393_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0 1102.0
HKD1_k127_809393_1 - - - - 0.00000000000000000000000000000002542 130.0
HKD1_k127_809393_2 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - 0.00000000000000000000004209 100.0
HKD1_k127_809393_3 Domain of unknown function (DUF4403) - - - 0.000000000000003885 76.0
HKD1_k127_809393_4 - - - - 0.0000001135 56.0
HKD1_k127_809393_5 - - - - 0.00002038 50.0
HKD1_k127_823456_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 426.0
HKD1_k127_823456_1 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001276 237.0
HKD1_k127_823456_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000289 232.0
HKD1_k127_823456_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000005562 226.0
HKD1_k127_823456_4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001864 205.0
HKD1_k127_823456_5 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000002428 179.0
HKD1_k127_823456_6 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000005092 139.0
HKD1_k127_823456_7 Ribosomal L29 protein K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000006199 99.0
HKD1_k127_85424_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 5.462e-266 827.0
HKD1_k127_85424_1 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000008875 215.0
HKD1_k127_85843_0 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 464.0
HKD1_k127_85843_1 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 287.0
HKD1_k127_85843_2 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001308 228.0
HKD1_k127_85843_3 abc transporter K01995 - - 0.00000000000002253 74.0