Overview

ID MAG01718
Name HKD1_bin.34
Sample SMP0046
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Bathyarchaeia
Order Bathyarchaeales
Family Bathycorpusculaceae
Genus UBA11855
Species
Assembly information
Completeness (%) 61.72
Contamination (%) 0.96
GC content (%) 46.0
N50 (bp) 7,799
Genome size (bp) 880,055

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes825

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1014345_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 2.783e-289 904.0
HKD1_k127_1014345_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.019e-204 649.0
HKD1_k127_1014345_10 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000001013 252.0
HKD1_k127_1014345_11 PFAM S-layer - - - 0.00000000000000000000000000000000000000000000000000000000000000002608 235.0
HKD1_k127_1014345_12 N2,N2-dimethylguanosine tRNA methyltransferase K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000005287 233.0
HKD1_k127_1014345_13 Helix-turn-helix domain K07731 - - 0.0000000000000000000000000000000000000000000000000000000000000008752 228.0
HKD1_k127_1014345_14 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000001527 207.0
HKD1_k127_1014345_15 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000008026 202.0
HKD1_k127_1014345_16 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000001042 193.0
HKD1_k127_1014345_17 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000004648 177.0
HKD1_k127_1014345_18 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.000000000000000000000000000000000000000001521 165.0
HKD1_k127_1014345_19 Domain of unknown function (DUF371) K09738 - - 0.00000000000000000000000000000004708 129.0
HKD1_k127_1014345_2 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 601.0
HKD1_k127_1014345_20 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.000000000000000009525 85.0
HKD1_k127_1014345_21 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000007926 79.0
HKD1_k127_1014345_22 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000000000003181 67.0
HKD1_k127_1014345_23 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000003049 67.0
HKD1_k127_1014345_24 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000001425 65.0
HKD1_k127_1014345_25 - - - - 0.0008684 44.0
HKD1_k127_1014345_3 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 572.0
HKD1_k127_1014345_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 561.0
HKD1_k127_1014345_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 566.0
HKD1_k127_1014345_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 526.0
HKD1_k127_1014345_7 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 505.0
HKD1_k127_1014345_8 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 404.0
HKD1_k127_1014345_9 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 387.0
HKD1_k127_1026989_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 428.0
HKD1_k127_1026989_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 296.0
HKD1_k127_1026989_2 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000871 273.0
HKD1_k127_1026989_3 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000002051 201.0
HKD1_k127_1026989_4 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000001083 162.0
HKD1_k127_1026989_5 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.0000000000000000000000000000000000000007976 150.0
HKD1_k127_1026989_6 PFAM glutaredoxin - - - 0.0000000000000002369 81.0
HKD1_k127_1026989_7 Mo-molybdopterin cofactor metabolic process K03753 - - 0.0000001319 53.0
HKD1_k127_1042934_0 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000007072 251.0
HKD1_k127_1042934_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.1.1.166 0.00000000000000000000005643 100.0
HKD1_k127_1042934_2 PFAM Glycosyltransferase 28 domain - - - 0.00000000000006346 83.0
HKD1_k127_1042934_3 - - - - 0.000000001518 66.0
HKD1_k127_1057205_0 double-strand break repair via homologous recombination K12614 GO:0000228,GO:0000722,GO:0000723,GO:0000724,GO:0000725,GO:0000781,GO:0000793,GO:0000794,GO:0000803,GO:0001674,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007059,GO:0007568,GO:0007569,GO:0008094,GO:0008150,GO:0008152,GO:0009410,GO:0009987,GO:0010033,GO:0010243,GO:0014070,GO:0014074,GO:0016043,GO:0016462,GO:0016604,GO:0016605,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019899,GO:0022402,GO:0030915,GO:0031000,GO:0031625,GO:0031974,GO:0031981,GO:0032200,GO:0032502,GO:0032991,GO:0033554,GO:0033676,GO:0034641,GO:0035061,GO:0035861,GO:0036270,GO:0042221,GO:0042493,GO:0042585,GO:0042592,GO:0042623,GO:0043073,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043279,GO:0044237,GO:0044238,GO:0044260,GO:0044389,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048518,GO:0048522,GO:0048869,GO:0050000,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051276,GO:0051304,GO:0051640,GO:0051641,GO:0051716,GO:0051983,GO:0051984,GO:0060249,GO:0065007,GO:0065008,GO:0070013,GO:0071139,GO:0071704,GO:0071840,GO:0090304,GO:0090398,GO:0090734,GO:0097159,GO:0097240,GO:0098687,GO:0106068,GO:1901360,GO:1901363,GO:1901698,GO:1902494,GO:1990234,GO:1990683 3.6.4.13 0.000000000000000007972 98.0
HKD1_k127_1057205_1 AAA domain - - - 0.00000000000000001054 98.0
HKD1_k127_1091309_0 Conserved region in glutamate synthase - - - 1.258e-231 726.0
HKD1_k127_1091309_1 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 499.0
HKD1_k127_1091309_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 308.0
HKD1_k127_1091309_3 GXGXG motif - - - 0.0000000000000000000000000000000000000000000000000000000001876 209.0
HKD1_k127_1105292_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 484.0
HKD1_k127_1105292_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 475.0
HKD1_k127_1105292_10 PIN domain of ribonuclease K07060 - - 0.00000000000000000000000001713 115.0
HKD1_k127_1105292_11 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000001698 91.0
HKD1_k127_1105292_12 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000000000001485 86.0
HKD1_k127_1105292_13 Sec61beta family - - - 0.0000000002419 62.0
HKD1_k127_1105292_14 MazG nucleotide pyrophosphohydrolase domain - - - 0.000000003827 60.0
HKD1_k127_1105292_15 - - - - 0.00000004457 54.0
HKD1_k127_1105292_2 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 351.0
HKD1_k127_1105292_3 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000002132 194.0
HKD1_k127_1105292_4 Pyruvate kinase, alpha/beta domain K09126 - - 0.0000000000000000000000000000000000000000000000001433 183.0
HKD1_k127_1105292_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000002667 183.0
HKD1_k127_1105292_6 Pfam:Methyltransf_26 K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000007377 176.0
HKD1_k127_1105292_7 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000006315 165.0
HKD1_k127_1105292_8 Predicted membrane protein (DUF2070) K08979 - - 0.00000000000000000000000000000000000000001007 174.0
HKD1_k127_1105292_9 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000009908 152.0
HKD1_k127_1111516_0 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001812 245.0
HKD1_k127_1111516_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000295 180.0
HKD1_k127_1111516_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000001545 68.0
HKD1_k127_1111516_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000003217 55.0
HKD1_k127_1114331_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 394.0
HKD1_k127_1114331_1 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 372.0
HKD1_k127_1114331_2 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 287.0
HKD1_k127_1114331_3 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000001779 270.0
HKD1_k127_1114331_4 tRNA (Uracil-5-)-methyltransferase - - - 0.00000000000000000000000000000000000000000000008625 176.0
HKD1_k127_1114331_5 Belongs to the eukaryotic ribosomal protein eL14 family K02875 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000005575 122.0
HKD1_k127_1114331_6 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.00000000000000000008215 92.0
HKD1_k127_1114331_7 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000003535 57.0
HKD1_k127_1139165_0 Protein of unknown function (DUF2961) K14109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 298.0
HKD1_k127_1139165_1 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000004417 278.0
HKD1_k127_1139165_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000004455 225.0
HKD1_k127_1139165_3 Formylmethanofuran-tetrahydromethanopterin formyltransferase K00672 - 2.3.1.101 0.00000000000000000000001106 102.0
HKD1_k127_1142944_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.518e-197 621.0
HKD1_k127_1142944_1 Tyrosine--tRNA ligase K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 400.0
HKD1_k127_1142944_2 DNA primase K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 352.0
HKD1_k127_1142944_3 COG0455 ATPases involved in chromosome partitioning K03496,K03609 - - 0.000000000000000000000000000000000000000000005366 173.0
HKD1_k127_1142944_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000001065 124.0
HKD1_k127_1142944_5 PUA domain K07575 - - 0.00000000000000000000000764 107.0
HKD1_k127_1142944_6 Transcriptional regulator, TrmB - - - 0.00000000000000000003226 95.0
HKD1_k127_1142944_7 Belongs to the UPF0292 family - - - 0.0000000000005215 74.0
HKD1_k127_1142944_8 Transcriptional regulator - - - 0.00003616 50.0
HKD1_k127_1144764_0 ABC-type cobalt transport system ATPase component K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 286.0
HKD1_k127_1144764_1 ATPases associated with a variety of cellular activities K16786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009787 255.0
HKD1_k127_1144764_2 PFAM Xylose isomerase domain protein TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000002686 253.0
HKD1_k127_1144764_3 DHH family - - - 0.000000000000000000000000000000000000000001965 168.0
HKD1_k127_1144764_4 PFAM Cobalt transport protein K16785 - - 0.0000000000000000000000000000000005291 141.0
HKD1_k127_1144764_5 Molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.00000000000000000000000000000004797 132.0
HKD1_k127_1144764_6 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000000001095 87.0
HKD1_k127_117507_0 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000001246 230.0
HKD1_k127_117507_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000003374 208.0
HKD1_k127_1194519_0 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005877 269.0
HKD1_k127_1194519_1 zinc finger - - - 0.0000000000000000000000000000000000000000000005144 176.0
HKD1_k127_1194519_2 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000002452 143.0
HKD1_k127_1194519_3 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.000000000000000000000000000000112 138.0
HKD1_k127_1194519_4 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.00000000000000000000004437 115.0
HKD1_k127_1205919_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000002912 239.0
HKD1_k127_1205919_1 Peptidyl-prolyl cis-trans isomerase K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000469 184.0
HKD1_k127_1205919_2 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000003338 129.0
HKD1_k127_1205919_3 helicase activity - - - 0.0000000000000000000002121 100.0
HKD1_k127_1205919_4 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.000000000000000000002508 95.0
HKD1_k127_1205919_5 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000009499 67.0
HKD1_k127_1218402_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 1.216e-195 629.0
HKD1_k127_1218402_1 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000004099 222.0
HKD1_k127_1218402_2 Glycosyl transferase family 4 K01001 GO:0003674,GO:0003824,GO:0003975,GO:0003976,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006040,GO:0006047,GO:0006066,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006488,GO:0006489,GO:0006490,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0016093,GO:0016094,GO:0016740,GO:0016772,GO:0016780,GO:0019348,GO:0019408,GO:0019538,GO:0019637,GO:0022607,GO:0030176,GO:0031224,GO:0031227,GO:0031984,GO:0034641,GO:0034645,GO:0036211,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046165,GO:0046465,GO:0046483,GO:0051259,GO:0055086,GO:0065003,GO:0070085,GO:0071704,GO:0071840,GO:0090407,GO:0098827,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.7.8.15 0.0000000000001751 81.0
HKD1_k127_1218402_3 Methyltransferase - - - 0.00000000001291 73.0
HKD1_k127_1218402_4 - - - - 0.0002209 47.0
HKD1_k127_1218771_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 391.0
HKD1_k127_1218771_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 330.0
HKD1_k127_1218771_2 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000004232 254.0
HKD1_k127_1218771_3 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000001257 211.0
HKD1_k127_1218771_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000001149 201.0
HKD1_k127_1218771_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000006733 200.0
HKD1_k127_1218771_6 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000002997 176.0
HKD1_k127_1218771_7 belongs to the PRA-CH family K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000005019 156.0
HKD1_k127_1218771_8 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000001282 97.0
HKD1_k127_1279869_0 Molybdenum cofactor synthesis domain protein K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 358.0
HKD1_k127_1279869_1 Molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000003689 241.0
HKD1_k127_1279869_2 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000184 240.0
HKD1_k127_1279869_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000139 208.0
HKD1_k127_1279869_4 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000005642 197.0
HKD1_k127_1324936_0 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 422.0
HKD1_k127_1324936_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000002137 161.0
HKD1_k127_1324936_2 COG0328 Ribonuclease HI K03469 - 3.1.26.4 0.00000000000000000000000002652 113.0
HKD1_k127_1324936_3 - - - - 0.0000001315 56.0
HKD1_k127_139226_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 406.0
HKD1_k127_139226_1 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 328.0
HKD1_k127_139226_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 318.0
HKD1_k127_139226_3 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000002669 166.0
HKD1_k127_139226_4 ECF-type riboflavin transporter, S component - - - 0.00000000000000000000000002279 113.0
HKD1_k127_139226_5 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000005619 113.0
HKD1_k127_139226_6 Iron-sulfur cluster-binding domain - - - 0.000000000000000000001739 106.0
HKD1_k127_139226_7 Glycosyl transferase family 2 K12992 - - 0.00000000000000000003083 100.0
HKD1_k127_1400175_0 - - - - 0.00000000000000000000000000000000000000000000000000000002114 204.0
HKD1_k127_1400175_1 - - - - 0.00000000000000000000000000000000291 139.0
HKD1_k127_1400175_2 PFAM MscS Mechanosensitive ion channel - - - 0.00002057 55.0
HKD1_k127_1400175_3 - - - - 0.00002454 50.0
HKD1_k127_152503_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 461.0
HKD1_k127_152503_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 334.0
HKD1_k127_152503_2 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000000000000000000000000000002771 154.0
HKD1_k127_152503_3 Transcription elongation factor - - - 0.00000000000000000000009076 106.0
HKD1_k127_152503_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000003167 92.0
HKD1_k127_1641114_0 Alpha/beta hydrolase family - - - 0.0000000000007345 79.0
HKD1_k127_1641114_1 Lactoylglutathione lyase K01759,K15772 - 4.4.1.5 0.00000000003727 70.0
HKD1_k127_1641114_2 Transcriptional regulator, TrmB - - - 0.00008687 55.0
HKD1_k127_164678_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 452.0
HKD1_k127_164678_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 404.0
HKD1_k127_164678_2 PFAM NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 392.0
HKD1_k127_164678_3 Male sterility protein K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000001495 258.0
HKD1_k127_164678_4 WxcM-like, C-terminal K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000006638 225.0
HKD1_k127_164678_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000002051 201.0
HKD1_k127_164678_6 Suf system fes assembly protein K04488,K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000003349 192.0
HKD1_k127_164678_7 - - - - 0.000000000000000000000000000000000000000000007663 175.0
HKD1_k127_164678_8 amine dehydrogenase activity K01113 - 3.1.3.1 0.00000005599 63.0
HKD1_k127_1658632_0 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 378.0
HKD1_k127_1658632_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 307.0
HKD1_k127_1658632_2 mevalonate kinase activity K00869,K15633 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006066,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006694,GO:0006695,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016126,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653 2.7.1.36,5.4.2.12 0.0000000000000000000000000000000000000000000000000000000001545 215.0
HKD1_k127_1658632_3 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000006019 144.0
HKD1_k127_1658632_4 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.000009353 48.0
HKD1_k127_169957_0 Psort location Cytoplasmic, score K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 320.0
HKD1_k127_169957_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.00000000000000000000000000000000000000000000000000001302 191.0
HKD1_k127_169957_2 NOL1 NOP2 sun family - - - 0.000000000000000000000000000000000000000000002311 177.0
HKD1_k127_169957_3 Uncharacterised protein family (UPF0113) K07565 - - 0.000001382 56.0
HKD1_k127_1776083_0 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000001494 249.0
HKD1_k127_1776083_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000007486 199.0
HKD1_k127_1776083_2 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000006418 162.0
HKD1_k127_1776083_3 integral membrane protein K07027 - - 0.000000000000004063 87.0
HKD1_k127_19072_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000001723 157.0
HKD1_k127_19072_1 Beta-galactosidase - - - 0.000000000000000000000000000000239 134.0
HKD1_k127_19072_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K11206 - - 0.000000000000000000000000004355 120.0
HKD1_k127_19072_3 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.000000000000003112 87.0
HKD1_k127_19072_4 4Fe-4S dicluster domain - - - 0.0000004544 54.0
HKD1_k127_2020358_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 499.0
HKD1_k127_2020358_1 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000304 206.0
HKD1_k127_2020358_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000006133 113.0
HKD1_k127_2020358_3 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000234 87.0
HKD1_k127_2020358_4 molybdopterin-guanine dinucleotide biosynthesis protein K03635 - 2.8.1.12 0.000000000000000003466 89.0
HKD1_k127_2037301_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 580.0
HKD1_k127_2037301_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 310.0
HKD1_k127_2037301_2 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000007305 268.0
HKD1_k127_2037301_3 Putative RNA methyltransferase K09142 - - 0.000000000000000000000000000000000000000000000000000000002412 210.0
HKD1_k127_2037301_4 Protein of unknown function DUF47 K07220 - - 0.0000002242 56.0
HKD1_k127_2148643_0 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.0 1029.0
HKD1_k127_2148643_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 8.714e-200 632.0
HKD1_k127_2148643_2 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 532.0
HKD1_k127_2148643_3 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 422.0
HKD1_k127_2148643_4 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear K00195 - - 0.000000000000000000000000000000000000000000000000000000629 197.0
HKD1_k127_2148643_5 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.0000000000000000000000000000000000000003408 152.0
HKD1_k127_2156547_0 PFAM beta-lactamase domain protein K07041 - - 1.945e-210 672.0
HKD1_k127_2156547_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000002049 221.0
HKD1_k127_2156547_2 Pfam:DUF552 K09152 - - 0.000000000000000000000006545 106.0
HKD1_k127_2156547_3 Transcriptional regulator PadR family protein K10947 - - 0.00000003227 61.0
HKD1_k127_2159044_0 Catalyzes the formation of phosphoenolpyruvate from pyruvate K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 343.0
HKD1_k127_2159044_1 TIGRFAM glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004613 276.0
HKD1_k127_2159044_2 Peptidase A4 family - - - 0.00000000000000000000000000000000004576 143.0
HKD1_k127_2159044_3 - - - - 0.000000000001088 70.0
HKD1_k127_2204379_0 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 481.0
HKD1_k127_2204379_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 419.0
HKD1_k127_2204379_2 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000855 246.0
HKD1_k127_2204379_3 Major facilitator superfamily K08161 - - 0.00000000000005468 84.0
HKD1_k127_2242632_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000002384 201.0
HKD1_k127_2242632_1 ATPases associated with a variety of cellular activities K09817 - - 0.0000000000000000000000000000000000000000000000000001052 193.0
HKD1_k127_2242632_2 - - - - 0.000001105 51.0
HKD1_k127_2242632_3 - - - - 0.00003401 48.0
HKD1_k127_2245852_0 MGS-like domain K01955 - 6.3.5.5 0.0 1137.0
HKD1_k127_2245852_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 462.0
HKD1_k127_2245852_2 homoserine kinase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 388.0
HKD1_k127_2245852_3 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 375.0
HKD1_k127_2245852_4 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 364.0
HKD1_k127_2245852_5 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000006388 254.0
HKD1_k127_2245852_6 - - - - 0.000000000000000006675 91.0
HKD1_k127_2245852_7 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000004554 74.0
HKD1_k127_2286410_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003258 277.0
HKD1_k127_2286410_1 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000002116 244.0
HKD1_k127_2286410_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000006714 211.0
HKD1_k127_2286410_3 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.000000000000000000000000006572 117.0
HKD1_k127_2317757_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 444.0
HKD1_k127_2317757_1 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 374.0
HKD1_k127_2317757_2 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000126 259.0
HKD1_k127_2317757_3 GNAT family acetyltransferase - - - 0.000000000000000000000000000000000000000000000000004513 186.0
HKD1_k127_2317757_4 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000003343 111.0
HKD1_k127_2317757_5 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00001377 58.0
HKD1_k127_2324098_0 hydroperoxide reductase activity - - - 0.00000000000000000000816 97.0
HKD1_k127_2324098_1 Vacuole effluxer Atg22 like - - - 0.000000000000000000008476 105.0
HKD1_k127_2357038_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 425.0
HKD1_k127_2357038_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003683 275.0
HKD1_k127_252088_0 Pfam:DUF39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 572.0
HKD1_k127_252088_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 392.0
HKD1_k127_252088_2 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 312.0
HKD1_k127_252088_3 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 296.0
HKD1_k127_252088_4 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001979 282.0
HKD1_k127_252088_5 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000006477 269.0
HKD1_k127_252088_6 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.0000000000000000000000000000000000000000000000005833 184.0
HKD1_k127_252088_7 Belongs to the UPF0280 family K09740 - - 0.0000000000000000000000000000000000000000002085 167.0
HKD1_k127_252088_8 4Fe-4S ferredoxin iron-sulfur binding - - - 0.000000000000000000000005872 106.0
HKD1_k127_252088_9 Belongs to the UPF0235 family K09131 - - 0.00000002771 59.0
HKD1_k127_2554087_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 340.0
HKD1_k127_2554087_1 COG0608 Single-stranded DNA-specific exonuclease K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 326.0
HKD1_k127_2554087_2 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001098 289.0
HKD1_k127_2554087_3 ribosomal protein S15 K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000003707 156.0
HKD1_k127_2554087_4 PFAM Methyltransferase type 11 - - - 0.0000000005025 70.0
HKD1_k127_2554087_5 - - - - 0.0002089 49.0
HKD1_k127_2608476_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 3.571e-232 732.0
HKD1_k127_2608476_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 298.0
HKD1_k127_2608476_2 Belongs to the phosphohexose mutase family K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000002271 248.0
HKD1_k127_262219_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 477.0
HKD1_k127_262219_1 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000001822 171.0
HKD1_k127_262219_2 Transcriptional regulator K07332 - - 0.000000000000000000000001344 111.0
HKD1_k127_262219_3 Domain of unknown function (DUF362) - - - 0.00000000002788 70.0
HKD1_k127_2762528_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 411.0
HKD1_k127_2762528_1 Domain of unknown function (DUF362) - - - 0.00000000000004272 76.0
HKD1_k127_28582_0 PFAM FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 578.0
HKD1_k127_28582_1 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000338 132.0
HKD1_k127_28582_2 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.000000000000000000000001247 108.0
HKD1_k127_28582_3 Belongs to the UPF0147 family K09721 - - 0.00000000000000000000002291 102.0
HKD1_k127_28582_4 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.0000000000005771 73.0
HKD1_k127_28582_5 PFAM thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000002391 71.0
HKD1_k127_28582_6 Transcriptional regulator K10947 - - 0.0000000008038 67.0
HKD1_k127_28582_7 - - - - 0.000001227 59.0
HKD1_k127_30003_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 606.0
HKD1_k127_30003_1 Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 344.0
HKD1_k127_3016950_0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 329.0
HKD1_k127_3016950_1 PFAM CBS domain containing protein - - - 0.0000000002174 72.0
HKD1_k127_3090582_0 PFAM TCP-1 cpn60 chaperonin family K22447 - - 1.578e-206 656.0
HKD1_k127_3090582_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 602.0
HKD1_k127_3090582_2 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 375.0
HKD1_k127_3090582_3 PFAM ATP-NAD AcoX kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 341.0
HKD1_k127_3090582_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000643 295.0
HKD1_k127_3090582_5 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000001586 132.0
HKD1_k127_3090582_6 regulator of amino acid metabolism K07103 - - 0.00000000000000000000000000000001861 132.0
HKD1_k127_3090582_7 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000003769 129.0
HKD1_k127_3090582_8 PAC2 family K07159 - - 0.000000000000000000000000000565 121.0
HKD1_k127_3090582_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03014,K03055 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000003915 93.0
HKD1_k127_3119237_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1322.0
HKD1_k127_3119237_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 5.838e-253 797.0
HKD1_k127_3119237_2 DNA methylase K00590 - 2.1.1.113 0.000000000000000000001914 96.0
HKD1_k127_3159973_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 341.0
HKD1_k127_3159973_1 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.00000000000000000000000000000000000000000000000000000000000002716 227.0
HKD1_k127_3159973_2 GH3 auxin-responsive promoter - - - 0.0000000000005135 79.0
HKD1_k127_3175080_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 4.317e-220 703.0
HKD1_k127_3175080_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000008539 175.0
HKD1_k127_3175080_2 PFAM Glycosyl transferase family 2 K07027 - - 0.0000000000000000000000000000000000000000001372 168.0
HKD1_k127_3175080_3 Domain of unknown function (DUF296) - - - 0.0000000000006473 69.0
HKD1_k127_3175080_4 Fibronectin type III domain K03933 - - 0.00000000004285 74.0
HKD1_k127_3175080_5 Winged helix-turn-helix - - - 0.000009181 51.0
HKD1_k127_3175080_6 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.00003046 57.0
HKD1_k127_3218712_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1073.0
HKD1_k127_3218712_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 348.0
HKD1_k127_3218712_10 Transcriptional regulator - - - 0.00009998 48.0
HKD1_k127_3218712_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 294.0
HKD1_k127_3218712_3 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002734 276.0
HKD1_k127_3218712_4 Phosphate uptake regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007091 267.0
HKD1_k127_3218712_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005787 262.0
HKD1_k127_3218712_6 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002293 248.0
HKD1_k127_3218712_7 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000007158 226.0
HKD1_k127_3218712_8 PhoU domain K02039 - - 0.00000000000000000000000000003788 125.0
HKD1_k127_3218712_9 - - - - 0.000000000000000000004703 98.0
HKD1_k127_3234998_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 458.0
HKD1_k127_3234998_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 364.0
HKD1_k127_3234998_2 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.0000000000000000000000000000000000000000000000000000000000000000000000223 250.0
HKD1_k127_3234998_3 heterodisulfide reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000001504 250.0
HKD1_k127_3234998_4 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000003547 120.0
HKD1_k127_3239298_0 malic enzyme K00027,K00029 - 1.1.1.38,1.1.1.40 9.087e-202 638.0
HKD1_k127_3239298_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.204e-201 640.0
HKD1_k127_3239298_10 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000893 97.0
HKD1_k127_3239298_11 COG1522 Transcriptional regulators - - - 0.0000000000000000001679 90.0
HKD1_k127_3239298_12 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000004158 80.0
HKD1_k127_3239298_13 archaeal coiled-coil protein - - - 0.000002702 58.0
HKD1_k127_3239298_2 GTPase of K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 430.0
HKD1_k127_3239298_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 304.0
HKD1_k127_3239298_4 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000094 283.0
HKD1_k127_3239298_5 Serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000002967 235.0
HKD1_k127_3239298_6 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000005553 190.0
HKD1_k127_3239298_7 K homology RNA-binding domain K06961 - - 0.0000000000000000000000000000000000000000000001687 173.0
HKD1_k127_3239298_8 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000003218 138.0
HKD1_k127_3239298_9 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000003249 116.0
HKD1_k127_3412755_0 component I K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 476.0
HKD1_k127_3412755_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 365.0
HKD1_k127_3412755_2 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000006907 247.0
HKD1_k127_3416948_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.454e-248 796.0
HKD1_k127_3416948_1 Belongs to the UPF0282 family K07022 - - 0.00000000000000000000000000000000000000000000000000000000000002966 226.0
HKD1_k127_3500153_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 509.0
HKD1_k127_3500153_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 399.0
HKD1_k127_3500153_10 PFAM PEGA domain - - - 0.0000000001741 72.0
HKD1_k127_3500153_11 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000000003406 62.0
HKD1_k127_3500153_12 LamG domain protein jellyroll fold domain protein K03418,K07151 - 2.4.99.18,3.5.1.56 0.00003845 55.0
HKD1_k127_3500153_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000004858 230.0
HKD1_k127_3500153_3 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000006599 219.0
HKD1_k127_3500153_4 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000002082 167.0
HKD1_k127_3500153_5 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.000000000000000000000000000000000000005109 149.0
HKD1_k127_3500153_6 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.0000000000000000000000001585 107.0
HKD1_k127_3500153_7 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000001683 95.0
HKD1_k127_3500153_8 Domain of unknown function (DUF4443) - - - 0.0000000000000002587 88.0
HKD1_k127_3500153_9 RNA-binding protein involved in rRNA processing K07569 - - 0.00000000000008934 74.0
HKD1_k127_351280_0 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 593.0
HKD1_k127_351280_1 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 304.0
HKD1_k127_351280_2 Thioredoxin reductase K00384,K03387 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 289.0
HKD1_k127_351280_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000007829 118.0
HKD1_k127_351280_4 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.0000000000000000000001286 103.0
HKD1_k127_351280_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000004077 91.0
HKD1_k127_351280_6 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000009742 86.0
HKD1_k127_351280_7 PFAM AMP-dependent synthetase and ligase K00666,K01897 - 6.2.1.3 0.0001222 46.0
HKD1_k127_355284_0 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 302.0
HKD1_k127_355284_1 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.00000000000000000000000000000000000002808 155.0
HKD1_k127_355284_2 Low-potential electron donor to a number of redox enzymes K03839,K03840 - - 0.0003215 45.0
HKD1_k127_3581001_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 379.0
HKD1_k127_3581001_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 377.0
HKD1_k127_3581001_2 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis K19003 - 2.4.1.336 0.00000000000000000000000000000000000000000000000000000000000000000004137 248.0
HKD1_k127_3581001_3 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000003175 144.0
HKD1_k127_3581001_4 PFAM transcriptional regulator PadR family protein - - - 0.0000000000000001237 85.0
HKD1_k127_3602093_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 1.251e-299 955.0
HKD1_k127_3602093_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004728 274.0
HKD1_k127_3602093_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000003995 241.0
HKD1_k127_3602093_3 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000006128 217.0
HKD1_k127_3602093_4 MazG nucleotide pyrophosphohydrolase domain - - - 0.00000000000000000000000000002589 120.0
HKD1_k127_3602093_5 Transcription elongation factor Elf1 like - - - 0.00000000003316 67.0
HKD1_k127_3984138_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 606.0
HKD1_k127_3984138_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 553.0
HKD1_k127_3984138_2 Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0008964,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0071704 4.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 505.0
HKD1_k127_3984138_3 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 358.0
HKD1_k127_3984138_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0000000000000000000000000000000000000000000000000000000006345 206.0
HKD1_k127_3984138_5 Ser thr protein kinase K07176 - - 0.000000000000000000000000000000000000000000000008722 180.0
HKD1_k127_3984138_6 Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000003106 174.0
HKD1_k127_3984138_7 COG1522 Transcriptional regulators - - - 0.00000002056 62.0
HKD1_k127_3984138_8 PFAM glycosyl transferase family 39 - - - 0.000005905 58.0
HKD1_k127_4039569_0 Belongs to the peptidase S16 family - - - 7.429e-309 965.0
HKD1_k127_4039569_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 377.0
HKD1_k127_4039569_2 ATP binding protein K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000007709 244.0
HKD1_k127_4039569_3 peptidase - - - 0.0000000000000000000000000000000000000000002276 168.0
HKD1_k127_4046166_0 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000232 186.0
HKD1_k127_4046166_1 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000001801 132.0
HKD1_k127_4046166_2 SnoaL-like domain - - - 0.00000000000000000000000001143 116.0
HKD1_k127_4046166_3 HAD-hyrolase-like K07025 - - 0.0000000000000006609 87.0
HKD1_k127_4046166_4 Transcriptional regulator - - - 0.00000001654 61.0
HKD1_k127_4046166_5 cell adhesion involved in biofilm formation - - - 0.0000001555 64.0
HKD1_k127_4056089_0 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000004482 214.0
HKD1_k127_4056089_1 - - - - 0.000000000000000008282 93.0
HKD1_k127_4056089_2 A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products K03552 - 3.1.22.4 0.0000004498 57.0
HKD1_k127_4056089_3 MacB-like periplasmic core domain K02004 - - 0.00001186 58.0
HKD1_k127_4060168_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.046e-250 796.0
HKD1_k127_4060168_1 Formylmethanofuran-tetrahydromethanopterin formyltransferase K00672 - 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 363.0
HKD1_k127_4060168_2 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 299.0
HKD1_k127_4060168_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003237 281.0
HKD1_k127_4060168_4 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.000000000000000000000000000000000000000000000000000000002885 214.0
HKD1_k127_4060168_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000004048 69.0
HKD1_k127_4065607_0 synthetase K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 500.0
HKD1_k127_4065607_1 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 453.0
HKD1_k127_4065607_2 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000149 282.0
HKD1_k127_4065607_3 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002941 251.0
HKD1_k127_4085558_0 DNA methylase K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 364.0
HKD1_k127_4089904_0 Protein of unknown function (DUF541) K09807 - - 0.000000000000003879 82.0
HKD1_k127_4089904_2 deoxyhypusine monooxygenase activity - - - 0.0000000002246 68.0
HKD1_k127_4089904_3 Fibronectin type III domain K03933 - - 0.0004836 51.0
HKD1_k127_4098677_0 HELICc2 K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000861 464.0
HKD1_k127_4098677_1 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000007485 104.0
HKD1_k127_4098677_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.000000000000000000001119 97.0
HKD1_k127_4098677_3 - - - - 0.0000000000006439 77.0
HKD1_k127_41084_0 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 616.0
HKD1_k127_41084_1 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000007459 263.0
HKD1_k127_41084_2 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000001056 84.0
HKD1_k127_41084_3 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000008501 81.0
HKD1_k127_4225733_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 539.0
HKD1_k127_4225733_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K00528,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 0.0000000000000000000000000009101 121.0
HKD1_k127_4225733_2 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000000000000000001125 108.0
HKD1_k127_4236_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 353.0
HKD1_k127_4236_1 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000003019 234.0
HKD1_k127_4236_2 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000001872 220.0
HKD1_k127_4236_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000002165 207.0
HKD1_k127_4236_4 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000003339 145.0
HKD1_k127_4236_5 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.0000000000000000000003085 114.0
HKD1_k127_4236_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000007732 102.0
HKD1_k127_4236_7 Transcriptional regulator PadR-like family - - - 0.00000000000008104 78.0
HKD1_k127_4236_8 ZIP Zinc transporter K07238,K16267 - - 0.0000000002328 65.0
HKD1_k127_4236_9 TOBE domain - - - 0.000000001024 60.0
HKD1_k127_4290013_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000938 281.0
HKD1_k127_4290013_1 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004288 282.0
HKD1_k127_4290013_2 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000002171 196.0
HKD1_k127_4290013_3 EamA-like transporter family - - - 0.000000000000000004998 95.0
HKD1_k127_4290013_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000004353 59.0
HKD1_k127_4290013_5 arginine decarboxylase activity K02626 - 4.1.1.19 0.0000005859 51.0
HKD1_k127_4511478_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 6.149e-244 764.0
HKD1_k127_4511478_1 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 429.0
HKD1_k127_4511478_10 protein conserved in bacteria - - - 0.000008332 52.0
HKD1_k127_4511478_2 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 372.0
HKD1_k127_4511478_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 350.0
HKD1_k127_4511478_4 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002188 264.0
HKD1_k127_4511478_5 Glutamine cyclotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006508 263.0
HKD1_k127_4511478_6 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000013 220.0
HKD1_k127_4511478_7 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000004536 123.0
HKD1_k127_4511478_8 Bacterio-opsin activator HTH K06930 - - 0.00000000000000000000001651 108.0
HKD1_k127_4511478_9 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000003036 78.0
HKD1_k127_4525957_0 PFAM Chaperonin Cpn60 TCP-1 K22447 - - 3.597e-196 627.0
HKD1_k127_4525957_1 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000139 115.0
HKD1_k127_4525957_2 Transcriptional regulator K07108 - - 0.0000000000000135 79.0
HKD1_k127_4525957_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000006228 54.0
HKD1_k127_4736255_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.299e-276 880.0
HKD1_k127_4736255_1 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000002561 84.0
HKD1_k127_4773180_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 392.0
HKD1_k127_4773180_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000004164 216.0
HKD1_k127_4773180_2 PFAM MOFRL domain protein K11529 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114 2.7.1.165 0.000000000000000000000000000000000000000309 153.0
HKD1_k127_4773180_3 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000002926 116.0
HKD1_k127_4773180_4 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.00001083 51.0
HKD1_k127_4798059_0 Glutamate synthase - - - 2.3e-220 694.0
HKD1_k127_4798059_1 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 561.0
HKD1_k127_4798059_10 RNA-binding protein of the translin family K07477 - - 0.0000000000000000000000000000004484 131.0
HKD1_k127_4798059_11 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000001149 112.0
HKD1_k127_4798059_12 binds to the 23S rRNA K02929 - - 0.00000000000000000000000001873 110.0
HKD1_k127_4798059_13 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000000003749 82.0
HKD1_k127_4798059_14 ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000001471 81.0
HKD1_k127_4798059_15 protein conserved in archaea K09723 - - 0.0000000000007279 76.0
HKD1_k127_4798059_16 GINS complex protein K09723 - - 0.000000003428 66.0
HKD1_k127_4798059_17 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00001476 48.0
HKD1_k127_4798059_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 479.0
HKD1_k127_4798059_3 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 387.0
HKD1_k127_4798059_4 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 345.0
HKD1_k127_4798059_5 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 314.0
HKD1_k127_4798059_6 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001366 272.0
HKD1_k127_4798059_7 Translation initiation factor 2 K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000008029 219.0
HKD1_k127_4798059_8 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000001074 181.0
HKD1_k127_4798059_9 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000002647 178.0
HKD1_k127_4909176_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000004799 246.0
HKD1_k127_4957711_0 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000008775 196.0
HKD1_k127_4957711_1 Acyltransferase family - - - 0.00000000001082 68.0
HKD1_k127_4957711_2 GYD domain - - - 0.00000598 52.0
HKD1_k127_5015785_0 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.00000000000000000000000000000000000000000005498 165.0
HKD1_k127_5015785_1 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904 - 0.000000000000000000000000000000000000000000132 167.0
HKD1_k127_5015785_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000002159 101.0
HKD1_k127_5015785_3 Belongs to the PDCD5 family K06875 - - 0.000000000000000000107 92.0
HKD1_k127_5015785_4 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000000000002647 87.0
HKD1_k127_5015785_5 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.000000000000001145 83.0
HKD1_k127_5015785_6 rRNA binding K02944 - - 0.000000000000008051 76.0
HKD1_k127_5015785_7 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000001307 54.0
HKD1_k127_5015785_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0008769 53.0
HKD1_k127_5050675_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 5.213e-195 624.0
HKD1_k127_5050675_1 SMART zinc finger, CDGSH-type domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001101 278.0
HKD1_k127_5050675_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000001703 160.0
HKD1_k127_5050675_3 TIGRFAM MoaD family protein K03636 - - 0.00000002049 61.0
HKD1_k127_5051408_0 Starch synthase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 531.0
HKD1_k127_5051408_1 Phosphofructokinase K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 405.0
HKD1_k127_5051408_2 Zn-dependent protease with chaperone function K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 381.0
HKD1_k127_5051408_3 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000001809 114.0
HKD1_k127_5051408_4 Peptidase A4 family - - - 0.000000000000000003905 91.0
HKD1_k127_5051408_5 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000002658 78.0
HKD1_k127_5051408_6 Acetyltransferase (GNAT) domain - - - 0.000001112 57.0
HKD1_k127_5051408_7 molybdopterin-guanine dinucleotide biosynthesis protein K03753,K13818 - 2.7.7.77 0.000002395 51.0
HKD1_k127_5102918_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000713 294.0
HKD1_k127_5102918_1 NADH ubiquinone oxidoreductase subunit 1 (Chain H) K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000005537 225.0
HKD1_k127_5102918_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K14091 - - 0.00000000000000000000001184 106.0
HKD1_k127_5102918_3 NADH ubiquinone oxidoreductase subunit 11 or 4L (chain K) K00340 - 1.6.5.3 0.0000003845 56.0
HKD1_k127_5102918_4 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.0003438 43.0
HKD1_k127_5158498_0 Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis K03341 - 2.9.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 348.0
HKD1_k127_5158498_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 290.0
HKD1_k127_5158498_2 PFAM DsrE family protein K07235 - - 0.0000000000000000000000000000001437 126.0
HKD1_k127_5158498_3 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000004776 71.0
HKD1_k127_5173465_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 339.0
HKD1_k127_5173465_1 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001118 257.0
HKD1_k127_5173465_10 Fcf1 K07158 - - 0.0000000000001203 76.0
HKD1_k127_5173465_11 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000001063 71.0
HKD1_k127_5173465_12 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.000000000002947 69.0
HKD1_k127_5173465_13 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000005467 70.0
HKD1_k127_5173465_14 - - - - 0.000001044 56.0
HKD1_k127_5173465_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000009027 231.0
HKD1_k127_5173465_3 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000002567 217.0
HKD1_k127_5173465_4 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000009673 182.0
HKD1_k127_5173465_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000005156 171.0
HKD1_k127_5173465_6 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000008112 153.0
HKD1_k127_5173465_7 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000000000000001049 130.0
HKD1_k127_5173465_8 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000009603 82.0
HKD1_k127_5173465_9 - - - - 0.00000000000003154 72.0
HKD1_k127_5208544_0 flavodoxin K00230 - 1.3.5.3 0.00000000000000000000000001003 116.0
HKD1_k127_5208544_1 Right handed beta helix region - - - 0.000000000005563 76.0
HKD1_k127_5208544_2 Flavodoxin K03809 - 1.6.5.2 0.000000008142 63.0
HKD1_k127_5208544_3 response to pH - - - 0.00007137 51.0
HKD1_k127_5225800_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 2.957e-315 978.0
HKD1_k127_5225800_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000004446 125.0
HKD1_k127_5230024_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.509e-306 960.0
HKD1_k127_5230024_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 548.0
HKD1_k127_5230024_10 PFAM TrkA-C domain protein - - - 0.000000000000000000000000000000001036 138.0
HKD1_k127_5230024_11 HTH DNA binding domain - - - 0.00000000000001215 78.0
HKD1_k127_5230024_12 AAA domain K07028 - - 0.000000004359 65.0
HKD1_k127_5230024_13 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000005344 55.0
HKD1_k127_5230024_2 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 310.0
HKD1_k127_5230024_3 Diphthamide K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000001822 206.0
HKD1_k127_5230024_4 MgtE integral membrane K07244 - - 0.0000000000000000000000000000000000000000000000000000000379 211.0
HKD1_k127_5230024_5 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000004007 158.0
HKD1_k127_5230024_6 TrkA-C domain - - - 0.0000000000000000000000000000000000000001549 158.0
HKD1_k127_5230024_7 Putative RNA methylase family UPF0020 - - - 0.0000000000000000000000000000000000000002247 166.0
HKD1_k127_5230024_8 Diphthamide synthase - - - 0.0000000000000000000000000000000000000004271 156.0
HKD1_k127_5230024_9 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000001699 155.0
HKD1_k127_5231240_0 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 304.0
HKD1_k127_5231240_1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000062 93.0
HKD1_k127_5231240_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000002877 88.0
HKD1_k127_5253302_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 346.0
HKD1_k127_5253302_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 299.0
HKD1_k127_5253302_2 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000003206 192.0
HKD1_k127_5254737_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 327.0
HKD1_k127_5254737_1 Nicotinamidase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000001942 222.0
HKD1_k127_5254737_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000008121 133.0
HKD1_k127_5268981_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 555.0
HKD1_k127_5268981_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 464.0
HKD1_k127_5268981_2 Belongs to the phosphohexose mutase family K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 418.0
HKD1_k127_5268981_3 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 308.0
HKD1_k127_5268981_4 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000005192 253.0
HKD1_k127_5268981_5 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000000000000006243 185.0
HKD1_k127_5268981_6 TIGRFAM nucleotide sugar dehydrogenase K02472 - 1.1.1.336 0.000000000000000000000000000000000005319 153.0
HKD1_k127_5319657_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000001429 239.0
HKD1_k127_5319657_1 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000000000000000021 195.0
HKD1_k127_5319657_2 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000001421 190.0
HKD1_k127_5319657_3 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000003273 151.0
HKD1_k127_5319657_4 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000000000000009851 138.0
HKD1_k127_5319657_5 RNA polymerase subunit 9 K03057 - - 0.000000000000000000000009157 104.0
HKD1_k127_5319657_6 Ribonuclease III - - - 0.00000000000101 74.0
HKD1_k127_5319657_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00008272 52.0
HKD1_k127_5334789_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 381.0
HKD1_k127_5334789_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.00000000000001863 74.0
HKD1_k127_5334789_2 transcriptional - - - 0.000000000001765 81.0
HKD1_k127_5334789_3 Archaeal transcriptional regulator TrmB - - - 0.00004144 52.0
HKD1_k127_5362146_0 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.000000000000000000000000000000000000003941 154.0
HKD1_k127_5362146_1 Uncharacterized protein conserved in archaea (DUF2095) - - - 0.000000000000000001629 89.0
HKD1_k127_5362146_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000007291 82.0
HKD1_k127_5362146_3 glycogen (starch) synthase activity K16149,K16150 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11,2.4.1.18 0.000002321 50.0
HKD1_k127_5450432_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 334.0
HKD1_k127_5450432_1 ABC-type Fe3 transport system permease component K02053,K02054,K02063 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 316.0
HKD1_k127_5450432_10 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.00000000000000000005438 91.0
HKD1_k127_5450432_11 binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000005013 81.0
HKD1_k127_5450432_12 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000001863 85.0
HKD1_k127_5450432_13 - - - - 0.00000000002073 72.0
HKD1_k127_5450432_14 Thioredoxin - - - 0.0000000711 58.0
HKD1_k127_5450432_15 - - - - 0.000172 49.0
HKD1_k127_5450432_2 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 305.0
HKD1_k127_5450432_3 PP-loop family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005986 277.0
HKD1_k127_5450432_4 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000003095 227.0
HKD1_k127_5450432_5 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000522 151.0
HKD1_k127_5450432_6 Cupin domain - - - 0.0000000000000000000000000000000000002506 145.0
HKD1_k127_5450432_7 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000003972 118.0
HKD1_k127_5450432_8 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K03658,K07466 - 3.6.4.12 0.00000000000000000000000003505 114.0
HKD1_k127_5450432_9 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000001855 104.0
HKD1_k127_5477656_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 463.0
HKD1_k127_5477656_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 398.0
HKD1_k127_5477656_2 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 321.0
HKD1_k127_5477656_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 290.0
HKD1_k127_5477656_4 Segregation and condensation complex subunit ScpB K06024 - - 0.00000000000000000000000000000000000022 147.0
HKD1_k127_5477656_5 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000001645 129.0
HKD1_k127_5477656_6 PFAM ribosomal protein S8E K02995 - - 0.0000000000000000000000000000007066 126.0
HKD1_k127_5477656_7 binds to the 23S rRNA K02921 - - 0.0000000000000000006893 89.0
HKD1_k127_5477656_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000005561 73.0
HKD1_k127_5477656_9 chromosome segregation and condensation protein ScpA K05896 - - 0.000002937 57.0
HKD1_k127_5492278_0 Amino acid kinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000004674 254.0
HKD1_k127_5492278_1 GIY-YIG catalytic domain K07461 - - 0.000000000000000002806 87.0
HKD1_k127_5492278_2 PFAM Haloacid dehalogenase domain protein hydrolase K01079 - 3.1.3.3 0.0002769 53.0
HKD1_k127_5517650_0 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 3.627e-210 666.0
HKD1_k127_5517650_1 PFAM TCP-1 cpn60 chaperonin family K22447 - - 5.54e-199 634.0
HKD1_k127_5517650_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 351.0
HKD1_k127_5517650_3 RIO-like serine threonine protein kinase fused to N-terminal HTH domain K07179 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000002435 251.0
HKD1_k127_5517650_4 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000005083 122.0
HKD1_k127_5517650_5 PIN domain K07063 - - 0.000000000000000000386 92.0
HKD1_k127_5517650_6 RNA-binding protein contains TRAM domain - - - 0.0000000002944 65.0
HKD1_k127_5517650_7 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00007901 46.0
HKD1_k127_5517650_8 toxin-antitoxin pair type II binding - - - 0.0005343 46.0
HKD1_k127_575047_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 360.0
HKD1_k127_575047_1 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 332.0
HKD1_k127_575047_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000001059 235.0
HKD1_k127_575047_3 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001465 220.0
HKD1_k127_575047_4 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.00000000000000000000000000000002087 132.0
HKD1_k127_6067108_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01535,K12952 - 3.6.3.6 0.0 1033.0
HKD1_k127_6067108_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000000009754 76.0
HKD1_k127_6099540_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 380.0
HKD1_k127_6099540_1 Belongs to the eukaryotic ribosomal protein eS4 family K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000002754 235.0
HKD1_k127_6099540_10 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.00000000000000000000000646 104.0
HKD1_k127_6099540_11 Binds 16S rRNA, required for the assembly of 30S particles K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008270,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:1990904 - 0.000000000000000002679 85.0
HKD1_k127_6099540_12 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000001172 58.0
HKD1_k127_6099540_13 rRNA binding K02940 GO:0000184,GO:0000956,GO:0002181,GO:0003002,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005773,GO:0005774,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0005911,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0007275,GO:0007389,GO:0007568,GO:0008104,GO:0008150,GO:0008152,GO:0008340,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009506,GO:0009507,GO:0009526,GO:0009536,GO:0009719,GO:0009892,GO:0009941,GO:0009955,GO:0009987,GO:0010033,GO:0010259,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0015031,GO:0015833,GO:0015934,GO:0016020,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0019538,GO:0022625,GO:0022626,GO:0030054,GO:0031090,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034645,GO:0034655,GO:0042221,GO:0042788,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045047,GO:0045184,GO:0046483,GO:0046700,GO:0046907,GO:0048519,GO:0048856,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0055044,GO:0060255,GO:0065007,GO:0070013,GO:0070727,GO:0070848,GO:0070887,GO:0070972,GO:0071310,GO:0071363,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0090304,GO:0097159,GO:0098588,GO:0098805,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1990089,GO:1990090,GO:1990904 - 0.000002841 50.0
HKD1_k127_6099540_2 Binds the lower part of the 30S subunit head K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000001592 234.0
HKD1_k127_6099540_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000112 214.0
HKD1_k127_6099540_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000008155 183.0
HKD1_k127_6099540_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000264 173.0
HKD1_k127_6099540_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000001112 153.0
HKD1_k127_6099540_7 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000002818 143.0
HKD1_k127_6099540_8 PFAM hydrogenase formation HypD protein K04654 - - 0.0000000000000000000000000000000000005081 143.0
HKD1_k127_6099540_9 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000002662 139.0
HKD1_k127_6167654_0 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 2.728e-209 662.0
HKD1_k127_6167654_1 Daunorubicin ABC transporter ATPase K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 297.0
HKD1_k127_6167654_2 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000003721 145.0
HKD1_k127_6201592_0 PFAM Orn Lys Arg decarboxylase major region K01582,K01584 - 4.1.1.18,4.1.1.19 2.304e-308 962.0
HKD1_k127_6201592_1 PFAM amino acid permease-associated region K20265 - - 2.208e-210 662.0
HKD1_k127_6201592_2 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 394.0
HKD1_k127_6327603_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000001376 153.0
HKD1_k127_6327603_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000001963 156.0
HKD1_k127_6327603_2 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000009714 128.0
HKD1_k127_6327603_3 Glycosyl transferase family 21 - - - 0.0000000000000000000000001999 118.0
HKD1_k127_6338567_0 Peptidase dimerisation domain K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 462.0
HKD1_k127_6338567_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 458.0
HKD1_k127_6338567_10 - - - - 0.000000000000000000000000000000000000000000000000000000009043 207.0
HKD1_k127_6338567_11 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000001861 202.0
HKD1_k127_6338567_12 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000002167 183.0
HKD1_k127_6338567_13 Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000000002463 141.0
HKD1_k127_6338567_14 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000005032 138.0
HKD1_k127_6338567_15 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.0000000000000000000000000000001818 129.0
HKD1_k127_6338567_16 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000405 124.0
HKD1_k127_6338567_17 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000004819 115.0
HKD1_k127_6338567_18 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000007349 106.0
HKD1_k127_6338567_19 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000001474 84.0
HKD1_k127_6338567_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 422.0
HKD1_k127_6338567_21 TIGRFAM cytidyltransferase-related domain K14656 - 2.7.7.2 0.00000000003097 67.0
HKD1_k127_6338567_22 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.0000000003534 64.0
HKD1_k127_6338567_3 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007703 425.0
HKD1_k127_6338567_4 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 376.0
HKD1_k127_6338567_5 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 323.0
HKD1_k127_6338567_6 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 297.0
HKD1_k127_6338567_7 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000154 253.0
HKD1_k127_6338567_8 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000002066 238.0
HKD1_k127_6338567_9 Zn-dependent protease with chaperone function K03799 - - 0.000000000000000000000000000000000000000000000000000000000006446 220.0
HKD1_k127_639825_0 Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 359.0
HKD1_k127_639825_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 333.0
HKD1_k127_639825_10 cyclopropane-fatty-acyl-phospholipid synthase K00574,K03466,K07154,K09846,K14369,K15256,K15257,K18534,K18827,K20444,K21192,K21457 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0044237,GO:0044249 2.1.1.210,2.1.1.254,2.1.1.281,2.1.1.294,2.1.1.295,2.1.1.79,2.7.1.181,2.7.11.1 0.000000000000000000000000001081 123.0
HKD1_k127_639825_11 Part of a membrane complex involved in electron transport K03614 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000001446 99.0
HKD1_k127_639825_12 Methionine biosynthesis protein MetW - - - 0.0000000000007542 78.0
HKD1_k127_639825_13 Part of a membrane complex involved in electron transport K03615 - - 0.0000000001581 73.0
HKD1_k127_639825_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 299.0
HKD1_k127_639825_3 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001305 289.0
HKD1_k127_639825_4 COG1520 FOG WD40-like repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000003594 263.0
HKD1_k127_639825_5 Belongs to the anaerobic coproporphyrinogen-III oxidase family K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.000000000000000000000000000000000000000000000000000000002036 216.0
HKD1_k127_639825_6 SMART Elongator protein 3 MiaB NifB K22227 - - 0.000000000000000000000000000000000000000000000000000000003691 213.0
HKD1_k127_639825_7 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000002159 198.0
HKD1_k127_639825_8 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000004361 194.0
HKD1_k127_639825_9 radical SAM domain protein - - - 0.00000000000000000000000000000000000006721 151.0
HKD1_k127_6422927_0 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 339.0
HKD1_k127_6422927_1 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.000000000000000000002437 97.0
HKD1_k127_6422927_2 Mazg nucleotide pyrophosphohydrolase - - - 0.00009942 49.0
HKD1_k127_6498440_0 DEAD DEAH box helicase domain protein K03724 - - 1.937e-250 804.0
HKD1_k127_6498440_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 4.278e-206 648.0
HKD1_k127_6498440_10 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000115 182.0
HKD1_k127_6498440_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000002698 167.0
HKD1_k127_6498440_12 Belongs to the UPF0200 family - - - 0.0000000000000000000000000000000000000000002183 165.0
HKD1_k127_6498440_13 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000217 139.0
HKD1_k127_6498440_14 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000001325 112.0
HKD1_k127_6498440_15 - - - - 0.00000000000000000000009056 104.0
HKD1_k127_6498440_16 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000272 98.0
HKD1_k127_6498440_17 Belongs to the UPF0201 family K09736 - - 0.0000000000000000918 85.0
HKD1_k127_6498440_18 Transcriptional regulator K07108 - - 0.0000000000001149 75.0
HKD1_k127_6498440_19 Short C-terminal domain - - - 0.000000214 55.0
HKD1_k127_6498440_2 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 534.0
HKD1_k127_6498440_20 COG0681 Signal peptidase I K13280 - 3.4.21.89 0.000001122 58.0
HKD1_k127_6498440_21 - - - - 0.000005312 50.0
HKD1_k127_6498440_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 530.0
HKD1_k127_6498440_4 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001853 287.0
HKD1_k127_6498440_5 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001014 284.0
HKD1_k127_6498440_6 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 242.0
HKD1_k127_6498440_7 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000008668 229.0
HKD1_k127_6498440_8 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000458 219.0
HKD1_k127_6498440_9 methylase K07446 - 2.1.1.213 0.00000000000000000000000000000000000000000000000001804 192.0
HKD1_k127_6518614_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 1.701e-203 651.0
HKD1_k127_6518614_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 485.0
HKD1_k127_6518614_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 451.0
HKD1_k127_6518614_3 PFAM THUMP domain protein K06963 - - 0.0000000000000000000000000000000001042 139.0
HKD1_k127_6518614_4 KEOPS complex Cgi121-like subunit K09119 - - 0.000000000005048 73.0
HKD1_k127_6628940_0 Belongs to the RtcB family K14415 GO:0000394,GO:0003674,GO:0003824,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.3 3.954e-194 617.0
HKD1_k127_6628940_1 Major Facilitator Superfamily - - - 0.00000000000000000000000007566 121.0
HKD1_k127_6628940_2 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914 3.1.2.6 0.00000000000000000207 90.0
HKD1_k127_6628940_3 Transglutaminase/protease-like homologues K01456 GO:0000224,GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006515,GO:0006516,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009100,GO:0009636,GO:0009719,GO:0009725,GO:0009751,GO:0009987,GO:0010033,GO:0010035,GO:0010188,GO:0010193,GO:0014070,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0030163,GO:0036211,GO:0042221,GO:0042493,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051603,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901700 3.5.1.52 0.000000005778 65.0
HKD1_k127_6628940_4 Sugar (and other) transporter K08151 - - 0.0002298 53.0
HKD1_k127_6905331_0 DEAD H associated K03724 - - 9.791e-213 694.0
HKD1_k127_6905331_1 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 459.0
HKD1_k127_6905331_2 Spore germination protein K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002862 257.0
HKD1_k127_6905331_3 Conserved protein implicated in secretion - - - 0.0000000000000000000000000000000000000000001547 166.0
HKD1_k127_6905331_4 xanthine phosphoribosyltransferase activity K00769,K07101 - 2.4.2.22 0.0000000000000000000000000000000000000000005421 164.0
HKD1_k127_6905331_5 vacuolar transport - - - 0.0000000000000000008357 97.0
HKD1_k127_6905331_6 elongation factor Tu domain 2 protein K03833 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000001043 92.0
HKD1_k127_6905331_7 Molybdopterin-guanine dinucleotide biosynthesis K03753,K13818 - 2.7.7.77 0.000000000000007998 80.0
HKD1_k127_6905331_8 - - - - 0.00001174 55.0
HKD1_k127_7071671_0 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K03294 - - 0.00000000000000000000000000000000000383 144.0
HKD1_k127_7071671_1 TIGRFAM SagB-type dehydrogenase domain - - - 0.0000000000000000000000000000007991 126.0
HKD1_k127_7071671_2 transcriptional regulator PadR family K10947 - - 0.000000000003836 74.0
HKD1_k127_7071671_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000005716 65.0
HKD1_k127_7071671_4 Protein of unknown function (DUF2400) - - - 0.00004496 55.0
HKD1_k127_7078168_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 621.0
HKD1_k127_7078168_1 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 291.0
HKD1_k127_7078168_2 Flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000003927 219.0
HKD1_k127_7118825_0 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001669 273.0
HKD1_k127_7118825_1 cytochrome-c peroxidase activity - - - 0.000000001112 67.0
HKD1_k127_7134745_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 483.0
HKD1_k127_7134745_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 349.0
HKD1_k127_7134745_2 virion core protein (lumpy skin disease virus) - - - 0.00000000000000000000000000000000000000000000000000001533 201.0
HKD1_k127_7134745_3 Lrp/AsnC ligand binding domain - - - 0.000001691 53.0
HKD1_k127_7134745_4 COG1522 Transcriptional regulators K03718 - - 0.0000621 48.0
HKD1_k127_7134745_5 - - - - 0.0002285 50.0
HKD1_k127_7134745_6 - - - - 0.0006569 51.0
HKD1_k127_7145287_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 334.0
HKD1_k127_7145287_1 Membrane protein of 12 TMs K01992,K07087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 310.0
HKD1_k127_7145287_2 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000006064 128.0
HKD1_k127_7145287_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000009679 57.0
HKD1_k127_7174570_0 PFAM Radical SAM domain protein K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 523.0
HKD1_k127_7174570_1 Glycerate kinase K11529 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 380.0
HKD1_k127_7174570_2 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000000000000000000000001052 179.0
HKD1_k127_7174570_3 TatD related DNase K03424 - - 0.000000000000000000000000000000000803 140.0
HKD1_k127_7174570_4 Cyclophilin-like K09143 - - 0.000000000000000000004 97.0
HKD1_k127_7174570_5 Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation - - - 0.000000000000006968 78.0
HKD1_k127_7174570_6 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000001784 63.0
HKD1_k127_7174570_7 S25 ribosomal protein K02975 - - 0.0000003136 57.0
HKD1_k127_7181429_0 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP-binding K00158 - 1.2.3.3 1.012e-253 797.0
HKD1_k127_7181429_1 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.000000000000000000000000000000000000000000000000000426 194.0
HKD1_k127_7181429_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000002846 140.0
HKD1_k127_7181429_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.00000000000000000000000000004886 123.0
HKD1_k127_7181429_4 Acetyltransferase (GNAT) domain - - - 0.00000000000002355 78.0
HKD1_k127_7181429_5 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.00000000001307 72.0
HKD1_k127_7181429_6 arsR family - - - 0.0003989 50.0
HKD1_k127_7187564_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 2.695e-225 714.0
HKD1_k127_7187564_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 321.0
HKD1_k127_7187564_2 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000000000000008932 189.0
HKD1_k127_7187564_3 PUA domain containing protein K07398 - - 0.00000000000000000000000000000000000000000002835 165.0
HKD1_k127_7187564_4 sugar kinase - - - 0.0000000000000000000001327 109.0
HKD1_k127_7187564_5 Transcriptional regulator, XRE family K03627 - - 0.000000000000000002627 92.0
HKD1_k127_7187564_6 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000001933 83.0
HKD1_k127_7187564_7 - - - - 0.000000007267 59.0
HKD1_k127_7400790_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 417.0
HKD1_k127_7400790_1 PAC2 family K07159 - - 0.0000000000000000000000000000000000000354 152.0
HKD1_k127_7400790_2 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000001735 113.0
HKD1_k127_7400790_3 PFAM Like-Sm ribonucleoprotein, core - - - 0.0000000000000000000000009877 108.0
HKD1_k127_7400790_4 nucleotidyl transferase K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000002673 94.0
HKD1_k127_7400790_5 PFAM beta-lactamase domain protein K07577 - - 0.00002314 47.0
HKD1_k127_7426202_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 5.806e-194 623.0
HKD1_k127_7426202_1 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 566.0
HKD1_k127_7426202_10 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000002307 234.0
HKD1_k127_7426202_11 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000001454 240.0
HKD1_k127_7426202_12 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000003566 227.0
HKD1_k127_7426202_13 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000004678 171.0
HKD1_k127_7426202_14 Efflux ABC transporter permease protein K02004 - - 0.00000000000000000000000000000000000000000001864 178.0
HKD1_k127_7426202_15 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000003037 145.0
HKD1_k127_7426202_16 NUDIX domain - - - 0.00000000000000000000000000000001903 131.0
HKD1_k127_7426202_17 PFAM phosphatidate cytidylyltransferase - - - 0.000000000000000000002161 102.0
HKD1_k127_7426202_19 PFAM NurA domain - - - 0.00000000000000000008586 101.0
HKD1_k127_7426202_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 446.0
HKD1_k127_7426202_20 amino acid-binding ACT - - - 0.0000000000000000008015 92.0
HKD1_k127_7426202_21 PFAM Ribosomal protein S30 K02983 - - 0.00000000502 59.0
HKD1_k127_7426202_3 COG0433 Predicted ATPase K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 407.0
HKD1_k127_7426202_4 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 383.0
HKD1_k127_7426202_5 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 383.0
HKD1_k127_7426202_6 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 325.0
HKD1_k127_7426202_7 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 310.0
HKD1_k127_7426202_8 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001486 260.0
HKD1_k127_7426202_9 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000155 260.0
HKD1_k127_7605349_0 Hopanoid biosynthesis associated radical SAM protein HpnJ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004582 265.0
HKD1_k127_7605349_1 - - - - 0.000184 54.0
HKD1_k127_7668119_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 3.311e-239 774.0
HKD1_k127_7668119_1 Pfam:DUF650 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 460.0
HKD1_k127_7668119_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000001158 151.0
HKD1_k127_7713330_0 Conserved protein implicated in secretion - - - 0.0000000000000000000000000000000000002638 149.0
HKD1_k127_7713330_1 - - - - 0.0000000000000000000000006354 110.0
HKD1_k127_7713330_2 - - - - 0.0000001166 54.0
HKD1_k127_7923292_0 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 7.925e-212 676.0
HKD1_k127_7923292_1 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 498.0
HKD1_k127_7923292_2 Major facilitator Superfamily K08217 - - 0.0000000000000000000000000000000000000000000001486 184.0
HKD1_k127_7923292_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000002566 107.0
HKD1_k127_7923292_4 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000002488 99.0
HKD1_k127_7923292_5 Universal stress protein family - - - 0.000000000001861 72.0
HKD1_k127_7969872_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.052e-288 902.0
HKD1_k127_7969872_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 481.0
HKD1_k127_7969872_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000001237 243.0
HKD1_k127_7978746_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 450.0
HKD1_k127_7978746_1 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 454.0
HKD1_k127_7978746_10 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000007705 136.0
HKD1_k127_7978746_11 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000168 108.0
HKD1_k127_7978746_12 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000004 97.0
HKD1_k127_7978746_13 - - - - 0.0005459 48.0
HKD1_k127_7978746_2 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 431.0
HKD1_k127_7978746_3 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 428.0
HKD1_k127_7978746_4 PFAM Glycosyl transferase, group 1 K16150 - 2.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 394.0
HKD1_k127_7978746_5 PFAM peptidase U62 modulator of DNA gyrase K03568 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0016787,GO:0019538,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 353.0
HKD1_k127_7978746_6 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 340.0
HKD1_k127_7978746_7 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006611 268.0
HKD1_k127_7978746_8 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000102 181.0
HKD1_k127_7978746_9 F420-0:Gamma-glutamyl ligase - - - 0.0000000000000000000000000000000000000001562 161.0
HKD1_k127_86757_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 554.0
HKD1_k127_86757_1 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 467.0
HKD1_k127_86757_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001905 246.0
HKD1_k127_86757_3 alkyl hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000006279 214.0
HKD1_k127_86757_4 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0000000000000000000000000000000001242 136.0
HKD1_k127_86757_5 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.00000000000000000000000001539 113.0
HKD1_k127_86757_6 pfam yhs - - - 0.00000000000007101 74.0
HKD1_k127_86757_7 PFAM Rubredoxin-type Fe(Cys)4 protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000002045 55.0
HKD1_k127_86757_8 OsmC-like protein - - - 0.0000001378 59.0
HKD1_k127_86757_9 PFAM Rubrerythrin - - - 0.0000002493 52.0