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Overview

ID MAG01719
Name HKD1_bin.36
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Limnocylindria
Order Limnocylindrales
Family CSP1-4
Genus
Species
Assembly information
Completeness (%) 55.24
Contamination (%) 0.01
GC content (%) 72.0
N50 (bp) 10,811
Genome size (bp) 1,977,300

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1698

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_1007040_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 461.0
HKD1_k127_1007040_1 Uridine phosphorylase K00757 - 2.4.2.3 0.000000000000000000000000000000000000000000000000000000000000006087 227.0
HKD1_k127_1007040_2 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.000000000000000000002654 111.0
HKD1_k127_1007040_3 - - - - 0.0000000000001032 72.0
HKD1_k127_1007040_4 Endonuclease Exonuclease Phosphatase - - - 0.00000000001297 79.0
HKD1_k127_1039772_0 PFAM regulatory protein LuxR K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 352.0
HKD1_k127_1039772_1 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000005634 128.0
HKD1_k127_1039772_2 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000002627 108.0
HKD1_k127_1039772_3 pyridoxamine 5-phosphate - - - 0.000000000000000000749 93.0
HKD1_k127_1039772_5 - - - - 0.000000000001762 70.0
HKD1_k127_1046529_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 400.0
HKD1_k127_1046529_1 PFAM Adenosine AMP deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 377.0
HKD1_k127_1046529_2 Exporter of polyketide antibiotics K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 381.0
HKD1_k127_1046529_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001081 226.0
HKD1_k127_1046529_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000001875 219.0
HKD1_k127_1046529_5 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000000000000000000002428 193.0
HKD1_k127_1046529_6 regulatory protein, arsR - - - 0.00000000000000000000000000000000000000001277 154.0
HKD1_k127_1056954_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 1.017e-197 630.0
HKD1_k127_1056954_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000001383 234.0
HKD1_k127_1056954_10 - - - - 0.00000000000000000001097 97.0
HKD1_k127_1056954_11 belongs to the sigma-70 factor family, ECF subfamily - - - 0.00000000000000000002174 103.0
HKD1_k127_1056954_12 - - - - 0.000000000000001101 82.0
HKD1_k127_1056954_2 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000000000000000000000002806 221.0
HKD1_k127_1056954_3 Phosphotriesterase family K07048 - - 0.0000000000000000000000000000000000000000000000000000000000007105 224.0
HKD1_k127_1056954_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000000000000000000000000000001071 193.0
HKD1_k127_1056954_5 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000005206 146.0
HKD1_k127_1056954_6 Cro/C1-type HTH DNA-binding domain K07729 - - 0.0000000000000000000000000000002241 126.0
HKD1_k127_1056954_7 VanW like protein - - - 0.000000000000000000000000000005328 138.0
HKD1_k127_1056954_8 ECF sigma factor K03088 - - 0.000000000000000000000000006419 117.0
HKD1_k127_1056954_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000001696 107.0
HKD1_k127_105812_0 ATP dependent DNA ligase C terminal region K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 472.0
HKD1_k127_105812_1 ABC transporter K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007522 244.0
HKD1_k127_105812_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000002047 216.0
HKD1_k127_105812_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000001423 138.0
HKD1_k127_105812_5 Cys/Met metabolism PLP-dependent enzyme K11325 - - 0.00000006486 58.0
HKD1_k127_1088811_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.792e-244 771.0
HKD1_k127_1088811_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 580.0
HKD1_k127_1088811_2 COG1404 Subtilisin-like serine proteases K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 422.0
HKD1_k127_1088811_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 428.0
HKD1_k127_1088811_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 314.0
HKD1_k127_1088811_5 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000002032 153.0
HKD1_k127_1088811_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000004699 134.0
HKD1_k127_1088811_7 Cupin - - - 0.0000000000000004874 87.0
HKD1_k127_1135458_0 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 624.0
HKD1_k127_1135458_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 300.0
HKD1_k127_1135458_2 EamA-like transporter family K11939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003311 271.0
HKD1_k127_1135458_3 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000002391 198.0
HKD1_k127_1135458_4 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488,K21053 - 3.5.4.2,3.5.4.4 0.000000000000000000000000000000000000000000000001845 196.0
HKD1_k127_1135458_5 - - - - 0.0000000000000000000008987 104.0
HKD1_k127_1135458_6 COG0681 Signal peptidase I K13280 - 3.4.21.89 0.000000000001939 78.0
HKD1_k127_1135458_7 SpoVT / AbrB like domain - - - 0.00000000001318 67.0
HKD1_k127_1135458_8 Large family of predicted nucleotide-binding domains - - - 0.000001187 58.0
HKD1_k127_129784_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 353.0
HKD1_k127_129784_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 332.0
HKD1_k127_129784_2 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003583 290.0
HKD1_k127_129784_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000007517 239.0
HKD1_k127_129784_4 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000003933 146.0
HKD1_k127_1305813_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 348.0
HKD1_k127_1305813_1 calcium, potassium:sodium antiporter activity K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001021 276.0
HKD1_k127_1305813_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000658 219.0
HKD1_k127_1305813_3 Evidence 2b Function of strongly homologous gene K02282 - - 0.0000000000000000000000000002465 129.0
HKD1_k127_1305813_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000006543 121.0
HKD1_k127_1305813_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963,K03111,K15125 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000002493 108.0
HKD1_k127_1305813_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000006786 95.0
HKD1_k127_1305813_7 Protein of unknown function (DUF1634) - - - 0.0000007319 61.0
HKD1_k127_1311234_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01668 - 4.1.99.2 1.185e-251 782.0
HKD1_k127_1311234_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 349.0
HKD1_k127_1311234_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000001174 229.0
HKD1_k127_1311234_3 sequence-specific DNA binding K00567,K13529,K15051 - 2.1.1.63,3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000002415 229.0
HKD1_k127_1311234_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000005252 142.0
HKD1_k127_1311234_5 CAAX protease self-immunity K07052 - - 0.00000000000000000000002639 109.0
HKD1_k127_1315394_0 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 474.0
HKD1_k127_1315394_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 425.0
HKD1_k127_1315394_10 - - - - 0.000000000000000000000000000000000000000000005816 173.0
HKD1_k127_1315394_11 SnoaL-like domain - - - 0.000000000003069 80.0
HKD1_k127_1315394_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 408.0
HKD1_k127_1315394_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 384.0
HKD1_k127_1315394_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 370.0
HKD1_k127_1315394_5 PFAM extracellular solute-binding protein family 1 K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 312.0
HKD1_k127_1315394_6 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001181 286.0
HKD1_k127_1315394_7 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005954 282.0
HKD1_k127_1315394_8 PFAM Inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000001492 229.0
HKD1_k127_1315394_9 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000007971 179.0
HKD1_k127_1338702_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 552.0
HKD1_k127_1338702_1 PFAM Phenylalanine and histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 504.0
HKD1_k127_1338702_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 406.0
HKD1_k127_1338702_3 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000004622 196.0
HKD1_k127_1338702_4 Phosphoglycerate mutase family K02226,K15634 - 3.1.3.73,5.4.2.12 0.000000000000000000000000000001365 129.0
HKD1_k127_1338702_6 Acetyltransferase (GNAT) family - - - 0.0000000105 67.0
HKD1_k127_1363780_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 346.0
HKD1_k127_1363780_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000004336 229.0
HKD1_k127_1363780_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000002618 103.0
HKD1_k127_1363780_3 (Rhomboid) family - - - 0.00000000000000002792 85.0
HKD1_k127_1363780_4 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000311 70.0
HKD1_k127_1444119_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 9.575e-218 688.0
HKD1_k127_1444119_1 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 440.0
HKD1_k127_1444119_10 Uncharacterized conserved protein (DUF2277) - - - 0.0000000008555 69.0
HKD1_k127_1444119_2 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 388.0
HKD1_k127_1444119_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001754 278.0
HKD1_k127_1444119_4 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001835 262.0
HKD1_k127_1444119_5 OsmC-like protein K09136 - - 0.00000000000000000000000000000000000000000000000005164 190.0
HKD1_k127_1444119_6 - - - - 0.00000000000000001631 95.0
HKD1_k127_1444119_7 Hemerythrin HHE cation binding domain - - - 0.0000000000000003139 85.0
HKD1_k127_1444119_8 negative regulation of transcription, DNA-templated - - - 0.0000000000005042 76.0
HKD1_k127_1444119_9 Hemerythrin HHE cation binding domain - - - 0.000000000001263 81.0
HKD1_k127_1506371_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 420.0
HKD1_k127_1506371_1 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000003995 206.0
HKD1_k127_1506371_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000001861 188.0
HKD1_k127_1506371_3 Uncharacterised protein family UPF0047 - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000002235 126.0
HKD1_k127_1506371_4 DUF167 K09131 - - 0.00000000000001464 77.0
HKD1_k127_1506371_5 integral membrane protein K02221 - - 0.00000000001151 67.0
HKD1_k127_1506371_6 - - - - 0.0000007102 58.0
HKD1_k127_1514756_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 2.341e-250 796.0
HKD1_k127_1514756_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 459.0
HKD1_k127_1514756_2 Belongs to the peptidase M24B family K01271,K01274 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 340.0
HKD1_k127_1514756_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000002049 152.0
HKD1_k127_1514756_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000007834 155.0
HKD1_k127_1514756_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000001815 93.0
HKD1_k127_1514756_6 PFAM CBS domain containing protein - - - 0.0000000000000001392 94.0
HKD1_k127_1514756_7 - - - - 0.00000565 54.0
HKD1_k127_159922_0 - - - - 4.76e-293 913.0
HKD1_k127_159922_1 Peptidase family M28 K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 476.0
HKD1_k127_1607610_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 583.0
HKD1_k127_1607610_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 589.0
HKD1_k127_1607610_2 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000001261 212.0
HKD1_k127_1610863_0 Mycobacterial 4 TMS phage holin, superfamily IV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 462.0
HKD1_k127_1610863_1 pfam abc1 K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009932 278.0
HKD1_k127_1610863_2 helix_turn_helix, Lux Regulon K03556 - - 0.000000000003965 72.0
HKD1_k127_1610863_3 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000001747 63.0
HKD1_k127_1610863_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000001296 59.0
HKD1_k127_1636525_0 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 1.051e-215 682.0
HKD1_k127_1636525_1 PFAM FGGY family of carbohydrate kinases, N-terminal domain - - - 3.226e-211 692.0
HKD1_k127_1636525_2 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 468.0
HKD1_k127_1636525_3 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006067 401.0
HKD1_k127_1636525_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 379.0
HKD1_k127_1636525_5 Monosaccharide ABC transporter ATP-binding protein, CUT2 family K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 371.0
HKD1_k127_1636525_6 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source K03077 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001345 275.0
HKD1_k127_1636525_7 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003956 292.0
HKD1_k127_1636525_9 PFAM Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.0000000000000001415 86.0
HKD1_k127_1662588_0 PFAM ABC transporter related K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002208 245.0
HKD1_k127_1662588_1 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.000000000000000000000000000000000000000000000000000000000003187 226.0
HKD1_k127_1662588_2 binding-protein-dependent transport systems inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000000000000004136 209.0
HKD1_k127_1662588_3 ABC transporter (Permease) K05846 - - 0.000000000000000000000000000000000000000000000000000000001751 217.0
HKD1_k127_1682343_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 521.0
HKD1_k127_1682343_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 445.0
HKD1_k127_1682343_2 TIGRFAM LPXTG-motif cell wall anchor domain - - - 0.0000000000000000000000000000000001968 144.0
HKD1_k127_1682343_3 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000009636 90.0
HKD1_k127_1682343_4 - - - - 0.0000000000009554 78.0
HKD1_k127_1682343_5 F420H(2)-dependent quinone reductase - - - 0.0001427 48.0
HKD1_k127_1692757_0 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 287.0
HKD1_k127_1692757_1 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.0000000000000000000000000004898 117.0
HKD1_k127_1692757_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000007175 128.0
HKD1_k127_169357_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.576e-225 737.0
HKD1_k127_169357_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 611.0
HKD1_k127_169357_10 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.00000000002606 77.0
HKD1_k127_169357_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000001373 65.0
HKD1_k127_169357_12 Baseplate J-like protein - - - 0.0000001872 64.0
HKD1_k127_169357_2 cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 376.0
HKD1_k127_169357_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001434 299.0
HKD1_k127_169357_4 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000002449 260.0
HKD1_k127_169357_5 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000002903 240.0
HKD1_k127_169357_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000001835 224.0
HKD1_k127_169357_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000001997 192.0
HKD1_k127_169357_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000007997 109.0
HKD1_k127_169357_9 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000197 87.0
HKD1_k127_1782680_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 484.0
HKD1_k127_1782680_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 447.0
HKD1_k127_1782680_10 NUBPL iron-transfer P-loop NTPase K02282 - - 0.00000000000000000000000008243 124.0
HKD1_k127_1782680_11 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000001493 91.0
HKD1_k127_1782680_12 cyclic nucleotide-binding - - - 0.0000000004692 68.0
HKD1_k127_1782680_13 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0005763 44.0
HKD1_k127_1782680_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 318.0
HKD1_k127_1782680_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000005427 279.0
HKD1_k127_1782680_4 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E - - - 0.00000000000000000000000000000000000000000000000000000000005571 224.0
HKD1_k127_1782680_5 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000003528 201.0
HKD1_k127_1782680_6 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000601 201.0
HKD1_k127_1782680_7 Flavin-binding monooxygenase-like - - - 0.0000000000000000000000000000000000000000000001074 190.0
HKD1_k127_1782680_8 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 0.0000000000000000000000000000000000002035 143.0
HKD1_k127_1782680_9 LysE type translocator - - - 0.00000000000000000000000000000000002985 151.0
HKD1_k127_1794286_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009436,GO:0009442,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042737,GO:0043436,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046700,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 316.0
HKD1_k127_1794286_1 Putative sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004514 273.0
HKD1_k127_1794286_2 SMP-30/Gluconolaconase/LRE-like region - - - 0.00000000000000000000000000000000000000000000000000000000000000006279 234.0
HKD1_k127_1794286_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000002992 181.0
HKD1_k127_1794286_5 PspC domain protein K03973 - - 0.00000000003137 71.0
HKD1_k127_1897410_0 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000001861 235.0
HKD1_k127_1897410_1 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000009869 190.0
HKD1_k127_1897410_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000007813 170.0
HKD1_k127_1897410_3 light absorption K01822 - 5.3.3.1 0.0007529 49.0
HKD1_k127_192220_0 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 454.0
HKD1_k127_192220_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 374.0
HKD1_k127_192220_10 sequence-specific DNA binding - - - 0.0001564 51.0
HKD1_k127_192220_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 316.0
HKD1_k127_192220_3 Homoserine dehydrogenase K00003,K12524 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000002591 257.0
HKD1_k127_192220_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000004237 257.0
HKD1_k127_192220_5 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000002341 221.0
HKD1_k127_192220_6 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000001004 119.0
HKD1_k127_192220_7 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000002061 100.0
HKD1_k127_192220_8 Transcriptional regulator - - - 0.0000000000001435 84.0
HKD1_k127_192220_9 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00006219 47.0
HKD1_k127_193289_0 Sulfatase K01130 - 3.1.6.1 0.0 1437.0
HKD1_k127_193289_1 Major facilitator superfamily - - - 5.844e-197 626.0
HKD1_k127_193289_2 radical SAM K06871 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 621.0
HKD1_k127_193289_3 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 494.0
HKD1_k127_193289_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 426.0
HKD1_k127_193289_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K12953 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 365.0
HKD1_k127_193289_6 PFAM CHAD domain containing protein - - - 0.0000000000000000000000000000001389 139.0
HKD1_k127_2029124_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 1.763e-227 736.0
HKD1_k127_2029124_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009727 527.0
HKD1_k127_2029124_2 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 340.0
HKD1_k127_2029124_3 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001081 276.0
HKD1_k127_2029124_4 E1-E2 ATPase K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000005537 192.0
HKD1_k127_2029124_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000001099 154.0
HKD1_k127_2029124_6 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000002618 155.0
HKD1_k127_2029124_7 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000003727 79.0
HKD1_k127_2029124_8 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000001245 58.0
HKD1_k127_2029124_9 Predicted permease K07089 - - 0.000002012 55.0
HKD1_k127_2051685_0 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 347.0
HKD1_k127_2051685_1 Homocysteine S-methyltransferase K00547,K21169 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 299.0
HKD1_k127_2051685_2 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000002334 208.0
HKD1_k127_2051685_3 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000001966 140.0
HKD1_k127_2051685_4 Amidohydrolase family K01464 - 3.5.2.2 0.000001612 50.0
HKD1_k127_2051685_5 SpoIIAA-like - - - 0.00006825 53.0
HKD1_k127_2060615_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 371.0
HKD1_k127_2060615_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 297.0
HKD1_k127_2060615_2 Iron-containing alcohol dehydrogenase K00096 - 1.1.1.261 0.0000000000000000000000000000000004711 144.0
HKD1_k127_2060615_3 efflux transmembrane transporter activity K02004 - - 0.00000000000000002739 95.0
HKD1_k127_2066228_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 308.0
HKD1_k127_2066228_1 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002683 281.0
HKD1_k127_2066228_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000001242 231.0
HKD1_k127_2066228_3 Cupin 2, conserved barrel domain protein K19547 - 5.3.3.19 0.0000000000000000000000000000001016 135.0
HKD1_k127_209058_0 Pterin binding enzyme K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 298.0
HKD1_k127_209058_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004604 262.0
HKD1_k127_209058_2 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000004675 260.0
HKD1_k127_209058_3 response regulator receiver K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000009318 218.0
HKD1_k127_209058_4 Histidine kinase K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000001561 190.0
HKD1_k127_209058_5 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000004585 122.0
HKD1_k127_209058_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000003894 114.0
HKD1_k127_209058_7 Methyltransferase - - - 0.000000000007684 74.0
HKD1_k127_2096470_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008794 467.0
HKD1_k127_2096470_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 386.0
HKD1_k127_2096470_2 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 351.0
HKD1_k127_2096470_3 Subtilase family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 327.0
HKD1_k127_2096470_4 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003173 276.0
HKD1_k127_2096470_5 cellulase activity - - - 0.0000000000000000000000000000007547 142.0
HKD1_k127_2096470_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000009415 57.0
HKD1_k127_2101571_0 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 4.164e-232 732.0
HKD1_k127_2101571_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 507.0
HKD1_k127_2101571_2 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 394.0
HKD1_k127_2101571_3 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000991 289.0
HKD1_k127_2101571_4 Potassium ABC transporter permease K01992 - - 0.00000000000000000000000000000000003782 153.0
HKD1_k127_2101571_5 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000000000000000009571 129.0
HKD1_k127_2101571_6 diguanylate cyclase - - - 0.0000000000000000008076 101.0
HKD1_k127_2101571_7 - - - - 0.000000000000000002414 93.0
HKD1_k127_2101571_8 succinate dehydrogenase activity K00242,K00246 - - 0.00000000000001832 76.0
HKD1_k127_2101571_9 Domain of unknown function (DUF4386) - - - 0.0000002455 57.0
HKD1_k127_2108560_0 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 469.0
HKD1_k127_2108560_1 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 373.0
HKD1_k127_2108560_2 transferase activity, transferring glycosyl groups K21369 - 2.4.1.270 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 331.0
HKD1_k127_2108560_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008588 299.0
HKD1_k127_2108560_4 WYL domain K07012,K13572 - - 0.000000000000000000000000000000000000000000000000000000004983 224.0
HKD1_k127_2108560_5 ABC transporter substrate-binding protein K02030,K02424,K17073 - - 0.000000000000000000000000000000003395 143.0
HKD1_k127_2108560_6 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway K01845 - 5.4.3.8 0.00000003393 57.0
HKD1_k127_2150297_0 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 586.0
HKD1_k127_2150297_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 369.0
HKD1_k127_2150297_2 ResB-like family - - - 0.00000000000000000000000000000000000000000006154 178.0
HKD1_k127_2150297_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000004473 158.0
HKD1_k127_2150297_4 Purine catabolism regulatory protein-like family K09684 - - 0.000000000001034 81.0
HKD1_k127_2150297_5 Belongs to the MEMO1 family K06990 - - 0.0007856 46.0
HKD1_k127_2190862_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 413.0
HKD1_k127_2190862_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 410.0
HKD1_k127_2190862_2 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000005093 176.0
HKD1_k127_2190862_3 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000002027 154.0
HKD1_k127_2190862_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.0000001532 61.0
HKD1_k127_225695_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 372.0
HKD1_k127_225695_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 325.0
HKD1_k127_225695_2 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000003777 251.0
HKD1_k127_225695_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000875 223.0
HKD1_k127_225695_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000001052 224.0
HKD1_k127_225695_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000002318 181.0
HKD1_k127_225695_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000005929 179.0
HKD1_k127_225695_7 May be required for sporulation K09762 - - 0.0000000000000006775 91.0
HKD1_k127_225695_8 Preprotein translocase SecG subunit K03075 - - 0.000000001003 63.0
HKD1_k127_2273092_0 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 292.0
HKD1_k127_2273092_1 Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source K01505,K05396 - 3.5.99.7,4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001557 280.0
HKD1_k127_2273092_2 META domain - - - 0.000000000000000000000000000000000000003966 162.0
HKD1_k127_2273092_3 YbhB YbcL family protein K06910 - - 0.00000000000000000000000000000000254 140.0
HKD1_k127_2273092_4 ECF sigma factor K03088 - - 0.0000000000000000000000000001193 123.0
HKD1_k127_2273092_5 response to heat K03668 - - 0.000000000000009707 88.0
HKD1_k127_2273092_6 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00002264 57.0
HKD1_k127_2305763_0 Belongs to the cysteine synthase cystathionine beta- synthase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 578.0
HKD1_k127_2305763_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000005424 238.0
HKD1_k127_2339049_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001833 244.0
HKD1_k127_2339049_1 - - - - 0.000000000001341 68.0
HKD1_k127_2339049_2 ubiE/COQ5 methyltransferase family - - - 0.00005114 50.0
HKD1_k127_2368370_0 Amylo-alpha-1,6-glucosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 564.0
HKD1_k127_2368370_1 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000498 282.0
HKD1_k127_2368370_2 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000001265 206.0
HKD1_k127_2368370_3 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000007142 138.0
HKD1_k127_2368370_4 Belongs to the HesB IscA family K13628 - - 0.00000000000000001443 82.0
HKD1_k127_2368370_5 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000001168 89.0
HKD1_k127_2368370_6 integral membrane protein - - - 0.000001573 57.0
HKD1_k127_2386062_0 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000007068 222.0
HKD1_k127_2386062_1 Sigma-70, region 4 K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000009405 108.0
HKD1_k127_2386062_2 Protein tyrosine kinase - - - 0.000000000001469 81.0
HKD1_k127_2405391_0 Beta-lactamase - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.000000000000000000000000000000000004774 147.0
HKD1_k127_2453394_0 Zn_pept - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 342.0
HKD1_k127_2453394_1 Luciferase-like monooxygenase - - - 0.00002242 48.0
HKD1_k127_24716_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008172 478.0
HKD1_k127_24716_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 447.0
HKD1_k127_24716_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 400.0
HKD1_k127_24716_3 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000323 286.0
HKD1_k127_24716_4 ABC-type Na efflux pump, permease K01992 - - 0.0000000000000000000000009196 121.0
HKD1_k127_24716_5 Protein of unknown function (DUF971) - - - 0.00000000000000000000000197 106.0
HKD1_k127_24716_6 ATP-dependent DNA ligase K01971 - 6.5.1.1 0.00000000000000000000002038 112.0
HKD1_k127_2494807_0 YbaK prolyl-tRNA synthetase associated region - - - 0.0000000000000000000000000000000000000000000000000000001057 201.0
HKD1_k127_2494807_1 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000000003059 193.0
HKD1_k127_2494807_2 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.0000000005207 62.0
HKD1_k127_2515920_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 540.0
HKD1_k127_2515920_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 533.0
HKD1_k127_2515920_10 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001333 242.0
HKD1_k127_2515920_11 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.0000000000000000000000000000000000000000000000000002348 206.0
HKD1_k127_2515920_12 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000000000000001382 193.0
HKD1_k127_2515920_13 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000001971 198.0
HKD1_k127_2515920_14 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000001585 175.0
HKD1_k127_2515920_15 Trypsin-like peptidase domain K04771 - 3.4.21.107 0.00000000000000000000000000000000000000005096 173.0
HKD1_k127_2515920_16 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000002 94.0
HKD1_k127_2515920_17 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000003194 103.0
HKD1_k127_2515920_18 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000000000004644 95.0
HKD1_k127_2515920_19 - - - - 0.000001428 61.0
HKD1_k127_2515920_2 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 489.0
HKD1_k127_2515920_20 Transcriptional regulatory protein, C terminal K02483,K07667 - - 0.0003787 53.0
HKD1_k127_2515920_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 333.0
HKD1_k127_2515920_4 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 323.0
HKD1_k127_2515920_5 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 293.0
HKD1_k127_2515920_6 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002969 284.0
HKD1_k127_2515920_7 histidine kinase dimerisation and phosphoacceptor region K03406,K07673,K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003284 297.0
HKD1_k127_2515920_8 NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
HKD1_k127_2515920_9 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000004529 262.0
HKD1_k127_253474_0 peptidase U62, modulator of DNA gyrase K03568 - - 1.153e-203 647.0
HKD1_k127_253474_1 peptidase U62, modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 379.0
HKD1_k127_253474_10 recombinase activity K07450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000004583 95.0
HKD1_k127_253474_11 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000006805 82.0
HKD1_k127_253474_2 FIST N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001777 310.0
HKD1_k127_253474_3 Chlorite dismutase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001576 260.0
HKD1_k127_253474_4 Ferrous iron transport B domain protein K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005236 274.0
HKD1_k127_253474_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000002741 243.0
HKD1_k127_253474_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000001872 220.0
HKD1_k127_253474_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000003981 201.0
HKD1_k127_253474_8 TIGRFAM HAD-superfamily hydrolase subfamily IA, variant K01091 - 3.1.3.18 0.000000000000000000000000000000000000000001512 160.0
HKD1_k127_253474_9 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000001323 144.0
HKD1_k127_2555752_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 1.785e-199 642.0
HKD1_k127_2555752_1 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 541.0
HKD1_k127_2555752_10 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000001562 214.0
HKD1_k127_2555752_11 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000009658 215.0
HKD1_k127_2555752_12 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000601 203.0
HKD1_k127_2555752_13 Histidine biosynthesis protein K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000001379 197.0
HKD1_k127_2555752_14 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000005226 183.0
HKD1_k127_2555752_15 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000002059 170.0
HKD1_k127_2555752_16 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000001047 163.0
HKD1_k127_2555752_17 Transcriptional regulator - - - 0.00000000000000000000000000000000005659 139.0
HKD1_k127_2555752_18 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000008323 142.0
HKD1_k127_2555752_19 PFAM Trp repressor - - - 0.00000000000000002659 88.0
HKD1_k127_2555752_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 496.0
HKD1_k127_2555752_20 Modulates RecA activity K03565 - - 0.00000000000000006959 88.0
HKD1_k127_2555752_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 422.0
HKD1_k127_2555752_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 383.0
HKD1_k127_2555752_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 363.0
HKD1_k127_2555752_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 337.0
HKD1_k127_2555752_7 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004232 277.0
HKD1_k127_2555752_8 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000461 257.0
HKD1_k127_2555752_9 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000006675 248.0
HKD1_k127_2591700_0 helix_turn_helix, Lux Regulon K11618 - - 0.0000000000000000000000000000000000000000000000000000000000001303 220.0
HKD1_k127_2591700_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000001848 195.0
HKD1_k127_2591700_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000877 130.0
HKD1_k127_2591700_3 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000003155 124.0
HKD1_k127_2591700_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000461 84.0
HKD1_k127_2591700_5 D-alanine [D-alanyl carrier protein] ligase activity K16428,K16429 - - 0.0000006053 62.0
HKD1_k127_2596943_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 461.0
HKD1_k127_2596943_1 AAA domain, putative AbiEii toxin, Type IV TA system K10010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001352 286.0
HKD1_k127_2596943_10 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000002515 79.0
HKD1_k127_2596943_11 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000003655 72.0
HKD1_k127_2596943_2 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000592 229.0
HKD1_k127_2596943_3 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.000000000000000000000000000000000000000000000000000000000000002157 233.0
HKD1_k127_2596943_4 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000001068 192.0
HKD1_k127_2596943_5 Belongs to the bacterial solute-binding protein 3 family - - - 0.00000000000000000000000000000000000000000002582 174.0
HKD1_k127_2596943_6 vancomycin resistance protein - - - 0.00000000000000000000000000000000000000008021 171.0
HKD1_k127_2596943_7 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.0000000000000000000000000003242 132.0
HKD1_k127_2596943_8 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.00000000000000000000000001051 125.0
HKD1_k127_2596943_9 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000617 101.0
HKD1_k127_261298_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000751 404.0
HKD1_k127_261298_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 383.0
HKD1_k127_261298_10 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate - - - 0.00000000000000000000000000000003042 127.0
HKD1_k127_261298_11 PFAM sigma-70 region 2 domain protein K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000001428 117.0
HKD1_k127_261298_12 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000002333 64.0
HKD1_k127_261298_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 368.0
HKD1_k127_261298_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 302.0
HKD1_k127_261298_4 tRNA synthetases class I (E and Q), catalytic domain K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001279 250.0
HKD1_k127_261298_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000006532 221.0
HKD1_k127_261298_6 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000002518 224.0
HKD1_k127_261298_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000003274 210.0
HKD1_k127_261298_8 InterPro IPR014922 - - - 0.00000000000000000000000000000000000000000005312 166.0
HKD1_k127_261298_9 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000001711 163.0
HKD1_k127_2624846_0 pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 409.0
HKD1_k127_2624846_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 394.0
HKD1_k127_2624846_10 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000001141 167.0
HKD1_k127_2624846_11 Transcriptional regulator - - - 0.0000000000000000000000000004258 123.0
HKD1_k127_2624846_12 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000344 101.0
HKD1_k127_2624846_13 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000205 91.0
HKD1_k127_2624846_16 - - - - 0.0000000835 63.0
HKD1_k127_2624846_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 312.0
HKD1_k127_2624846_3 GTP cyclohydrolase I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001327 268.0
HKD1_k127_2624846_4 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000008857 211.0
HKD1_k127_2624846_5 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000004486 220.0
HKD1_k127_2624846_6 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000002018 211.0
HKD1_k127_2624846_7 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000001165 208.0
HKD1_k127_2624846_8 TIGRFAM HAD-superfamily hydrolase subfamily IA, variant K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000037 202.0
HKD1_k127_2624846_9 - - - - 0.00000000000000000000000000000000000000000000000421 180.0
HKD1_k127_263576_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.682e-241 763.0
HKD1_k127_263576_1 Methionine synthase B12-binding module cap domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000033 224.0
HKD1_k127_263576_2 methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000003593 180.0
HKD1_k127_263576_3 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000002758 175.0
HKD1_k127_263576_4 Histidine kinase-like ATPases - - - 0.00000000000000000000000003463 124.0
HKD1_k127_2660169_0 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 482.0
HKD1_k127_2660169_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 366.0
HKD1_k127_2660169_10 - - - - 0.000000000000000904 89.0
HKD1_k127_2660169_11 Dodecin K09165 - - 0.0000000007718 63.0
HKD1_k127_2660169_12 Protein of unknown function (DUF1232) - - - 0.0000001223 60.0
HKD1_k127_2660169_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000004966 274.0
HKD1_k127_2660169_3 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000009401 217.0
HKD1_k127_2660169_4 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000002951 225.0
HKD1_k127_2660169_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000001312 205.0
HKD1_k127_2660169_6 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000004173 132.0
HKD1_k127_2660169_7 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000006678 130.0
HKD1_k127_2660169_8 Formiminotransferase-cyclodeaminase - - - 0.0000000000000000000001434 107.0
HKD1_k127_2660169_9 Glycosyltransferase family 87 - - - 0.00000000000000000001278 106.0
HKD1_k127_2661605_0 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 403.0
HKD1_k127_2661605_1 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005716 307.0
HKD1_k127_2661605_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000004653 163.0
HKD1_k127_2661605_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000001201 141.0
HKD1_k127_2661605_4 Double zinc ribbon - - - 0.00000000000000000001392 105.0
HKD1_k127_2661605_5 hyperosmotic response K04065 - - 0.000000000000000002202 94.0
HKD1_k127_2661605_6 Transglycosylase associated protein - - - 0.00000000000002646 78.0
HKD1_k127_2749501_0 Stage II sporulation E family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 525.0
HKD1_k127_2749501_1 Transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 391.0
HKD1_k127_2749501_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000003136 186.0
HKD1_k127_2749501_3 Histidine kinase - - - 0.00000000000000000000000000000000000000001583 174.0
HKD1_k127_2749501_4 antisigma factor binding K03090,K04749,K06378 - - 0.0000000000000000000000000005844 116.0
HKD1_k127_2749501_6 Histidine kinase - - - 0.00000002709 57.0
HKD1_k127_2749501_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.0003026 49.0
HKD1_k127_2805000_0 ApbE family K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000001347 280.0
HKD1_k127_2805000_1 TfoX N-terminal domain - - - 0.00000000000000000000000000000000001064 141.0
HKD1_k127_2805000_2 nitric oxide dioxygenase activity - - - 0.00000000000000000003606 92.0
HKD1_k127_2832684_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.437e-225 706.0
HKD1_k127_2832684_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 624.0
HKD1_k127_2832684_10 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000007974 181.0
HKD1_k127_2832684_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000008463 152.0
HKD1_k127_2832684_12 Prephenate dehydrogenase K00210,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 0.000000000000000000000000000007404 136.0
HKD1_k127_2832684_13 NUDIX hydrolase - - - 0.0000000000000000000000000004294 130.0
HKD1_k127_2832684_14 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000002955 81.0
HKD1_k127_2832684_15 protein with SCP PR1 domains - - - 0.0000003562 63.0
HKD1_k127_2832684_16 - - - - 0.0003277 47.0
HKD1_k127_2832684_17 N-Acetylmuramoyl-L-alanine amidase K01176,K01448 GO:0003674,GO:0005198,GO:0005199,GO:0005575,GO:0005623,GO:0008150,GO:0009273,GO:0009987,GO:0030115,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944 3.2.1.1,3.5.1.28 0.0003712 53.0
HKD1_k127_2832684_2 Peptidase dimerisation domain K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 492.0
HKD1_k127_2832684_3 magnesium chelatase, ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 422.0
HKD1_k127_2832684_4 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 321.0
HKD1_k127_2832684_5 Membrane-bound serine protease (ClpP class) K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000005836 254.0
HKD1_k127_2832684_6 PFAM response regulator receiver K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000001061 259.0
HKD1_k127_2832684_7 Participates in initiation and elongation during chromosome replication K02314,K02316,K17680 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000001258 247.0
HKD1_k127_2832684_8 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000002951 179.0
HKD1_k127_2832684_9 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000001069 170.0
HKD1_k127_2850144_0 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 427.0
HKD1_k127_2850144_1 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 399.0
HKD1_k127_2850144_2 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000005128 170.0
HKD1_k127_2850144_3 Psort location Cytoplasmic, score K02529 - - 0.00000000000274 68.0
HKD1_k127_2902182_0 Beta-eliminating lyase K01667 - 4.1.99.1 2.055e-229 725.0
HKD1_k127_2902182_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07669,K07672 - - 0.0000000000000000000000000000000000000000000000000000000299 209.0
HKD1_k127_2902182_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000203 198.0
HKD1_k127_2902182_3 - - - - 0.00007081 56.0
HKD1_k127_2940857_0 MreB/Mbl protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 454.0
HKD1_k127_2940857_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 377.0
HKD1_k127_2940857_2 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000001227 253.0
HKD1_k127_2940857_3 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000001338 232.0
HKD1_k127_2940857_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000001138 216.0
HKD1_k127_2940857_5 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000003229 207.0
HKD1_k127_2940857_6 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000004772 153.0
HKD1_k127_2940857_7 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000009787 140.0
HKD1_k127_2940857_8 Involved in formation and maintenance of cell shape K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - 0.000000000002085 78.0
HKD1_k127_2940857_9 CAAX protease self-immunity K07052 - - 0.0000003712 59.0
HKD1_k127_3047935_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 595.0
HKD1_k127_3047935_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 413.0
HKD1_k127_3047935_10 - - - - 0.00000001611 64.0
HKD1_k127_3047935_2 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 364.0
HKD1_k127_3047935_3 Zinc-binding dehydrogenase K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 361.0
HKD1_k127_3047935_4 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 302.0
HKD1_k127_3047935_5 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000001605 245.0
HKD1_k127_3047935_6 Allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000000000000000000000000000000002483 214.0
HKD1_k127_3047935_7 - - - - 0.00000000000000000000000000000000000000000000000003482 187.0
HKD1_k127_3047935_8 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000000003075 160.0
HKD1_k127_3047935_9 Allophanate hydrolase, subunit 1 - - - 0.000000000000001058 77.0
HKD1_k127_3065250_0 PFAM Lipopolysaccharide kinase (Kdo WaaP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 399.0
HKD1_k127_3065250_1 Nitroreductase family - - - 0.00000000000000000000000000000000004073 140.0
HKD1_k127_3065250_2 PFAM luciferase-like K00320 - 1.5.98.2 0.0000000000000000000000006726 121.0
HKD1_k127_3065250_3 Methyltransferase domain - - - 0.0000000000000000005648 102.0
HKD1_k127_3065250_4 Redoxin - - - 0.0000000000000003949 92.0
HKD1_k127_3065250_5 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000002658 76.0
HKD1_k127_3065250_6 Tellurite resistance protein TerB K05801 - - 0.000000008146 65.0
HKD1_k127_3065250_7 Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role K09994 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019634,GO:0019637,GO:0033051,GO:0044237,GO:0044424,GO:0044464,GO:0071704,GO:1901564 - 0.0000004326 61.0
HKD1_k127_3065250_8 FR47-like protein - - - 0.0001084 54.0
HKD1_k127_3074568_0 AIR synthase related protein, C-terminal domain K01952 - 6.3.5.3 7.052e-199 649.0
HKD1_k127_3074568_1 AICARFT/IMPCHase bienzyme K00602 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 572.0
HKD1_k127_3074568_10 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000002871 101.0
HKD1_k127_3074568_11 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000003054 84.0
HKD1_k127_3074568_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 490.0
HKD1_k127_3074568_3 tRNA synthetases class I (C) catalytic domain K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 441.0
HKD1_k127_3074568_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 440.0
HKD1_k127_3074568_5 SAICAR synthetase K01923,K01945 - 6.3.2.6,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 342.0
HKD1_k127_3074568_6 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 315.0
HKD1_k127_3074568_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001827 254.0
HKD1_k127_3074568_8 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000002406 201.0
HKD1_k127_3074568_9 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000003818 176.0
HKD1_k127_3124235_0 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000007265 242.0
HKD1_k127_3124235_1 PFAM OsmC-like protein K04063 - - 0.0000000006801 60.0
HKD1_k127_3129093_0 Evidence 5 No homology to any previously reported sequences - - - 2.307e-273 872.0
HKD1_k127_3129093_1 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 6.443e-214 680.0
HKD1_k127_3129093_3 PFAM regulatory protein GntR HTH K22293 - - 0.000000000000000000000000000000000000000000000000000000000000004534 225.0
HKD1_k127_3129093_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000001467 213.0
HKD1_k127_3129093_5 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.0000000000000000000000000000000000000000000001495 180.0
HKD1_k127_3169510_0 Alpha amylase, catalytic domain K21350 - 2.4.1.329 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 540.0
HKD1_k127_3169510_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 449.0
HKD1_k127_3169510_2 ABC transporter (Permease) K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 370.0
HKD1_k127_3169510_3 PFAM binding-protein-dependent transport systems inner membrane component K10119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 374.0
HKD1_k127_3169510_4 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000002043 194.0
HKD1_k127_3169510_5 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000001184 184.0
HKD1_k127_3169510_6 transcriptional regulator - - - 0.00000000000000000000000000000002539 136.0
HKD1_k127_3169510_7 Heparinase II/III-like protein - - - 0.000000000000000009252 94.0
HKD1_k127_3169510_8 Domain of unknown function (DUF4260) - - - 0.000002502 54.0
HKD1_k127_3179992_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 361.0
HKD1_k127_3179992_1 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 286.0
HKD1_k127_3179992_2 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004906 271.0
HKD1_k127_3179992_3 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000005412 253.0
HKD1_k127_3179992_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000001304 218.0
HKD1_k127_3179992_5 Methyltransferase type 12 - - - 0.00000000000000000000000005007 121.0
HKD1_k127_3179992_6 NUBPL iron-transfer P-loop NTPase K02282 - - 0.00000000000000000000009606 111.0
HKD1_k127_3179992_7 PFAM PfkB domain protein - - - 0.0000000000000008458 90.0
HKD1_k127_3179992_8 Helix-turn-helix domain - - - 0.0004091 52.0
HKD1_k127_3192122_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 489.0
HKD1_k127_3192122_1 Putative regulatory protein - - - 0.00000002436 63.0
HKD1_k127_3192122_2 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.0001846 53.0
HKD1_k127_3199885_0 Protein of unknown function (DUF642) - - - 0.0000000000000000000001411 109.0
HKD1_k127_3199885_1 methylglyoxal synthase K01734 - 4.2.3.3 0.0000000114 57.0
HKD1_k127_3268875_0 Excinuclease ATPase subunit - - - 0.0 1101.0
HKD1_k127_3268875_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 3.854e-242 766.0
HKD1_k127_3268875_2 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.405e-237 760.0
HKD1_k127_3268875_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 371.0
HKD1_k127_3335394_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1050.0
HKD1_k127_3335394_1 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 430.0
HKD1_k127_3335394_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000002655 229.0
HKD1_k127_3335394_3 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000002869 218.0
HKD1_k127_3335394_4 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000001514 166.0
HKD1_k127_3335394_5 Sigma-70 region 2 K03088 - - 0.0000000000001291 79.0
HKD1_k127_3335394_6 protein phosphatase 2C domain protein - - - 0.0000259 51.0
HKD1_k127_3339943_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 499.0
HKD1_k127_3339943_1 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 483.0
HKD1_k127_3339943_10 Pfam:DUF385 - - - 0.00000000000000000000009039 109.0
HKD1_k127_3339943_11 ThiS family K03636 - - 0.0000000000000000000002049 111.0
HKD1_k127_3339943_12 Serine hydrolase - - - 0.000000000000000006173 95.0
HKD1_k127_3339943_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 468.0
HKD1_k127_3339943_3 Pyridoxal-phosphate dependent enzyme K01883,K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 389.0
HKD1_k127_3339943_4 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 398.0
HKD1_k127_3339943_5 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003935 247.0
HKD1_k127_3339943_6 L11 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000525 205.0
HKD1_k127_3339943_7 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000001854 145.0
HKD1_k127_3339943_8 Belongs to the cysteine synthase cystathionine beta- synthase family - - - 0.000000000000000000000000000000003824 130.0
HKD1_k127_3339943_9 Mov34 MPN PAD-1 family K21140 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.13.1.6 0.00000000000000000000000002683 114.0
HKD1_k127_3352900_0 Phosphofructokinase K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 343.0
HKD1_k127_3352900_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 332.0
HKD1_k127_3352900_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000005987 106.0
HKD1_k127_3352900_3 RDD family - - - 0.000000004419 66.0
HKD1_k127_3418088_0 carbamate kinase K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 407.0
HKD1_k127_3418088_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00822,K00833 - 2.6.1.18,2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 314.0
HKD1_k127_3418088_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000004812 83.0
HKD1_k127_3418088_11 Cyclic-di-AMP receptor - - - 0.000000004568 64.0
HKD1_k127_3418088_12 Cupin domain - - - 0.0000897 53.0
HKD1_k127_3418088_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 306.0
HKD1_k127_3418088_3 RNA-metabolising metallo-beta-lactamase K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002675 287.0
HKD1_k127_3418088_4 phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit K00479,K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002903 292.0
HKD1_k127_3418088_5 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006883 271.0
HKD1_k127_3418088_6 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000309 271.0
HKD1_k127_3418088_7 - K06862 - - 0.0000000000000000000000000000000000000000000000000246 192.0
HKD1_k127_3418088_8 coenzyme F420 binding - - - 0.0000000000000000000000000000000000003806 150.0
HKD1_k127_3418088_9 ArsC family - - - 0.000000000000000000000000000000000007909 149.0
HKD1_k127_344757_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 5.927e-253 799.0
HKD1_k127_344757_1 Dak1 domain K05878 - 2.7.1.121 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 527.0
HKD1_k127_344757_10 Dak2 K05879 - 2.7.1.121 0.000000000000000000000000000000000000000002421 164.0
HKD1_k127_344757_11 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000002372 169.0
HKD1_k127_344757_12 PTS system fructose IIA component K05881 - 2.7.1.121 0.00000000000000000000000000005646 126.0
HKD1_k127_344757_13 succinate dehydrogenase K00241,K00247 - - 0.00000000000000000003763 97.0
HKD1_k127_344757_14 Belongs to the PEP-utilizing enzyme family K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000007641 74.0
HKD1_k127_344757_15 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000003707 57.0
HKD1_k127_344757_2 Hemerythrin HHE cation binding domain K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 459.0
HKD1_k127_344757_3 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 445.0
HKD1_k127_344757_4 Major intrinsic protein K02440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 305.0
HKD1_k127_344757_5 Dak2 K05879 - 2.7.1.121 0.000000000000000000000000000000000000000000000000000000000000000003194 233.0
HKD1_k127_344757_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000006184 216.0
HKD1_k127_344757_7 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000003273 192.0
HKD1_k127_344757_8 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000004645 184.0
HKD1_k127_344757_9 Dak2 K05879 - 2.7.1.121 0.00000000000000000000000000000000000000000001452 180.0
HKD1_k127_3453482_0 ABC transporter K06147 - - 5.659e-242 776.0
HKD1_k127_3453482_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 416.0
HKD1_k127_3453482_2 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.0000000000000000000000000008604 116.0
HKD1_k127_3453482_3 PFAM OsmC family protein K07397 - - 0.000000000000000004063 96.0
HKD1_k127_3453482_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000003189 58.0
HKD1_k127_3453482_5 GGDEF domain - - - 0.00002793 57.0
HKD1_k127_3572885_0 Fe-S cluster domain protein - - - 6.448e-244 797.0
HKD1_k127_3572885_1 Isocitrate/isopropylmalate dehydrogenase K00030,K00031 - 1.1.1.41,1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 539.0
HKD1_k127_3572885_10 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.0000000000000000000001013 113.0
HKD1_k127_3572885_11 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000001716 96.0
HKD1_k127_3572885_12 ADP-Ribose Pyrophosphatase - - - 0.00000000004283 72.0
HKD1_k127_3572885_2 PFAM ABC transporter related K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 379.0
HKD1_k127_3572885_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 390.0
HKD1_k127_3572885_4 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009292 344.0
HKD1_k127_3572885_5 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 317.0
HKD1_k127_3572885_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000001112 213.0
HKD1_k127_3572885_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000005987 181.0
HKD1_k127_3572885_8 Cobalt transport protein K16785 - - 0.00000000000000000000000000000000518 138.0
HKD1_k127_3572885_9 phosphorelay sensor kinase activity K16923,K18967 - 2.7.7.65 0.00000000000000000000000007125 121.0
HKD1_k127_3592480_0 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007025 253.0
HKD1_k127_3592480_1 Probable zinc-ribbon domain - - - 0.00000000000000000000000000009173 126.0
HKD1_k127_3592480_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000009062 109.0
HKD1_k127_3592480_3 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.000000000000000593 91.0
HKD1_k127_3592480_4 Mannosyltransferase (PIG-V) - - - 0.000000000001379 79.0
HKD1_k127_3592480_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0002636 54.0
HKD1_k127_3601316_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1073.0
HKD1_k127_3601316_1 Chromate K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 358.0
HKD1_k127_3601316_2 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 322.0
HKD1_k127_3601316_3 Isochorismatase family K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000009875 212.0
HKD1_k127_3601316_4 Iron permease FTR1 family K07243 - - 0.0000000000000000000000000000000000000000000000000000000003302 221.0
HKD1_k127_3601316_5 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000004352 160.0
HKD1_k127_3601316_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000001838 99.0
HKD1_k127_3601316_7 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.000000000004641 72.0
HKD1_k127_3601316_8 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.00000000002833 71.0
HKD1_k127_3601316_9 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.00000000005813 75.0
HKD1_k127_3628030_0 Sulfate transporter K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 371.0
HKD1_k127_3628030_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 299.0
HKD1_k127_3628030_2 His Kinase A (phosphoacceptor) domain K07654 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000105 287.0
HKD1_k127_3628030_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000001154 262.0
HKD1_k127_3628030_4 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000000000000000000000003811 193.0
HKD1_k127_3628030_5 AMMECR1 domain-containing protein K09141 - - 0.00000000000000000000000000000008649 132.0
HKD1_k127_3628030_6 membrane protein of uknown function UCP014873 - - - 0.00000000000000000000000001744 115.0
HKD1_k127_3628877_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 309.0
HKD1_k127_3628877_1 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000004027 220.0
HKD1_k127_3628877_2 PolyA polymerase K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000007535 208.0
HKD1_k127_3628877_3 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000001187 167.0
HKD1_k127_3628877_4 Psort location Cytoplasmic, score K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000002213 143.0
HKD1_k127_3628877_5 Glyoxalase-like domain - - - 0.0000000000001022 78.0
HKD1_k127_3628877_6 cellulose synthase K20543 - - 0.000135 51.0
HKD1_k127_3672131_0 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 365.0
HKD1_k127_3672131_1 Ferric reductase like transmembrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 346.0
HKD1_k127_3672131_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000001505 223.0
HKD1_k127_3672131_3 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000008648 84.0
HKD1_k127_3672131_4 belongs to the sigma-70 factor family, ECF subfamily - - - 0.00000000006756 70.0
HKD1_k127_3672131_5 FMN-binding domain protein - - - 0.0000000006087 70.0
HKD1_k127_3672131_6 Domain of unknown function (DUF4143) K07133 - - 0.0000002242 58.0
HKD1_k127_3672131_7 Recombinase - - - 0.000004255 59.0
HKD1_k127_3672131_8 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00005736 46.0
HKD1_k127_3723935_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 548.0
HKD1_k127_3723935_1 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 493.0
HKD1_k127_3723935_10 Pfam:DUF385 - - - 0.000000003597 65.0
HKD1_k127_3723935_2 Acetolactate synthase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 303.0
HKD1_k127_3723935_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003865 248.0
HKD1_k127_3723935_4 PFAM Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000003794 215.0
HKD1_k127_3723935_5 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000000000000003144 175.0
HKD1_k127_3723935_6 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000000000000000005366 173.0
HKD1_k127_3723935_7 PFAM Bacterial regulatory protein, arsR family - - - 0.00000000000000000000000000000000000000004416 156.0
HKD1_k127_3723935_8 PFAM VanW family protein - - - 0.0000000000000000000000000000003586 141.0
HKD1_k127_3723935_9 Domain of unknown function (DU1801) - - - 0.0000000000000000000003521 107.0
HKD1_k127_3788445_0 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 498.0
HKD1_k127_3788445_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 331.0
HKD1_k127_3788445_2 Sporulation and spore germination - - - 0.000000000000000000000000000000000000000000000000000000000008952 229.0
HKD1_k127_3788445_3 LURP-one-related - - - 0.0000000000000000000000000000000000000000000000000008649 194.0
HKD1_k127_3788445_4 AI-2E family transporter - - - 0.0000000000000000000000000000000171 146.0
HKD1_k127_3788445_6 permease - - - 0.000000000000000298 93.0
HKD1_k127_3788445_7 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.000000000003267 81.0
HKD1_k127_3788445_8 Glycosyltransferase Family 4 - - - 0.0003016 53.0
HKD1_k127_3905622_0 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0 1465.0
HKD1_k127_3905622_1 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 566.0
HKD1_k127_3905622_2 DEAD H associated domain protein K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 476.0
HKD1_k127_3905622_3 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000002428 226.0
HKD1_k127_3905622_4 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000009196 177.0
HKD1_k127_3905622_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.000000000000000000004379 101.0
HKD1_k127_3905622_6 - - - - 0.0000000006729 66.0
HKD1_k127_3975686_0 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 435.0
HKD1_k127_3975686_1 Cytochrome b/b6/petB K03891 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003411 266.0
HKD1_k127_3975686_10 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000003448 83.0
HKD1_k127_3975686_11 Sigma-70 region 2 - - - 0.0000000000001896 78.0
HKD1_k127_3975686_12 Diguanylate cyclase - - - 0.0000000000007348 79.0
HKD1_k127_3975686_13 Prolyl oligopeptidase family - - - 0.000000001489 71.0
HKD1_k127_3975686_14 Domain of unknown function (DUF309) K09763 - - 0.00000003567 64.0
HKD1_k127_3975686_16 PFAM blue (type 1) copper domain protein - - - 0.0000001977 63.0
HKD1_k127_3975686_17 Kelch motif - - - 0.00004616 56.0
HKD1_k127_3975686_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000001164 168.0
HKD1_k127_3975686_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000002539 134.0
HKD1_k127_3975686_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000005923 130.0
HKD1_k127_3975686_5 Rieske 2Fe-2S - - - 0.00000000000000000000000008187 116.0
HKD1_k127_3975686_6 Rhodanese Homology Domain - - - 0.0000000000000000000000026 113.0
HKD1_k127_3975686_7 ECF sigma factor K03088 - - 0.00000000000000000000001521 108.0
HKD1_k127_3975686_8 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000129 102.0
HKD1_k127_3975686_9 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000002434 92.0
HKD1_k127_4032999_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 614.0
HKD1_k127_4032999_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 350.0
HKD1_k127_4032999_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.000000000000000000000000000000000000000000000000000004808 196.0
HKD1_k127_4032999_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000002384 186.0
HKD1_k127_4032999_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000002158 138.0
HKD1_k127_4032999_5 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000002747 55.0
HKD1_k127_4052717_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 462.0
HKD1_k127_4052717_1 PFAM Glycoside hydrolase, family 38 K01191,K15524 - 3.2.1.170,3.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 417.0
HKD1_k127_4052717_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000007506 207.0
HKD1_k127_4052717_3 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000004115 188.0
HKD1_k127_4052717_4 YwiC-like protein - - - 0.00000000000000000000006986 108.0
HKD1_k127_4052717_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000002648 95.0
HKD1_k127_4054940_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1182.0
HKD1_k127_4054940_1 Neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 321.0
HKD1_k127_4054940_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006931 281.0
HKD1_k127_4054940_3 Carboxylate--amine ligase - - - 0.000000000000000000000000000000000000000000000001079 187.0
HKD1_k127_4054940_4 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000199 160.0
HKD1_k127_4054940_5 membrane - - - 0.000000000000000000000000000000005712 146.0
HKD1_k127_4054940_6 Secreted repeat of unknown function - - - 0.0000000000000000000000000001713 129.0
HKD1_k127_4054940_7 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000002542 79.0
HKD1_k127_4055829_0 FeS assembly protein SufB K09014 - - 8.985e-224 702.0
HKD1_k127_4055829_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 450.0
HKD1_k127_4055829_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000002597 129.0
HKD1_k127_4055829_11 AraC-like ligand binding domain - - - 0.00000000000000000000007344 101.0
HKD1_k127_4055829_12 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000002766 109.0
HKD1_k127_4055829_13 Rieske-like [2Fe-2S] domain K05710 - - 0.00000000000000002001 85.0
HKD1_k127_4055829_14 TIGRFAM FeS assembly protein SufD K09015 - - 0.000000000000002616 78.0
HKD1_k127_4055829_15 AI-2E family transporter - - - 0.00000000000007516 85.0
HKD1_k127_4055829_16 Anti-sigma-K factor rskA - - - 0.0000005633 62.0
HKD1_k127_4055829_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 425.0
HKD1_k127_4055829_3 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001099 281.0
HKD1_k127_4055829_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000003632 210.0
HKD1_k127_4055829_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000001631 190.0
HKD1_k127_4055829_6 Ornithine cyclodeaminase/mu-crystallin family - - - 0.0000000000000000000000000000000000000003127 162.0
HKD1_k127_4055829_7 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000105 157.0
HKD1_k127_4055829_8 asnC family K03719 - - 0.000000000000000000000000000000005515 134.0
HKD1_k127_4055829_9 Domain of unknown function (DUF4203) - - - 0.000000000000000000000000000000129 132.0
HKD1_k127_4059789_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 486.0
HKD1_k127_4059789_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 345.0
HKD1_k127_4059789_10 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000009992 81.0
HKD1_k127_4059789_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000003625 79.0
HKD1_k127_4059789_12 RecF RecN SMC N terminal domain-containing protein - - - 0.000001576 59.0
HKD1_k127_4059789_2 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 319.0
HKD1_k127_4059789_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007353 291.0
HKD1_k127_4059789_4 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000006603 232.0
HKD1_k127_4059789_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000006677 191.0
HKD1_k127_4059789_6 Peptidase family S51 - - - 0.0000000000000000000000000000001343 136.0
HKD1_k127_4059789_7 Calcineurin-like phosphoesterase K03547 - - 0.00000000000000000000000000000194 136.0
HKD1_k127_4059789_8 Probable zinc-ribbon domain - - - 0.00000000000000000000000000001771 124.0
HKD1_k127_4059789_9 Molybdopterin oxidoreductase K00123 - 1.17.1.9 0.000000000000000000000000006907 119.0
HKD1_k127_4104781_0 Aldo/keto reductase family K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 554.0
HKD1_k127_4104781_1 cystathionine beta-lyase K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 327.0
HKD1_k127_4104781_10 - K01992,K19341 - - 0.0000000881 64.0
HKD1_k127_4104781_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 311.0
HKD1_k127_4104781_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001002 281.0
HKD1_k127_4104781_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002139 287.0
HKD1_k127_4104781_5 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000000000000000000000001536 231.0
HKD1_k127_4104781_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000006922 201.0
HKD1_k127_4104781_7 aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000009853 142.0
HKD1_k127_4104781_8 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000246 122.0
HKD1_k127_4104781_9 Haloacid dehalogenase-like hydrolase - - - 0.00000002042 65.0
HKD1_k127_4123474_0 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 1.593e-232 756.0
HKD1_k127_4123474_1 Bacterial extracellular solute-binding protein K10117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 430.0
HKD1_k127_4123474_2 Periplasmic binding protein LacI transcriptional regulator K17640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 419.0
HKD1_k127_4123474_3 Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 358.0
HKD1_k127_4123474_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 288.0
HKD1_k127_4123474_5 DRTGG domain K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003513 269.0
HKD1_k127_4123474_6 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000001482 215.0
HKD1_k127_4123474_7 binding-protein-dependent transport systems inner membrane component K10119 - - 0.0000000000000000000000000000000000000000001004 175.0
HKD1_k127_4123474_8 - - - - 0.000000000000000000003823 98.0
HKD1_k127_4145736_0 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000001073 179.0
HKD1_k127_4145736_1 Hemerythrin hhe cation binding - - - 0.00000000000000000000000000000000001432 149.0
HKD1_k127_4145736_2 Protein of unknown function (DUF998) - - - 0.00000000000000001674 92.0
HKD1_k127_4145736_3 HxlR-like helix-turn-helix - - - 0.0000000002872 68.0
HKD1_k127_4145736_4 glyoxalase III activity - - - 0.00001422 53.0
HKD1_k127_4161548_0 glycoside hydrolase 15-related K01178 - 3.2.1.3 0.0 1369.0
HKD1_k127_4161548_1 tetrahydromethanopterin reductase - - - 2.504e-204 644.0
HKD1_k127_4161548_10 L-asparaginase II K01424 - 3.5.1.1 0.0000000000000000634 87.0
HKD1_k127_4161548_2 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 330.0
HKD1_k127_4161548_3 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 295.0
HKD1_k127_4161548_4 fmn reductase K00299 - 1.5.1.38 0.000000000000000000000000000000000000000000000000000000000000007806 232.0
HKD1_k127_4161548_5 Belongs to the glycosyl hydrolase 13 family K01200 - 3.2.1.41 0.000000000000000000000000000000000000000000000000000000000009327 238.0
HKD1_k127_4161548_6 ferrous iron binding K06990,K15755 - - 0.000000000000000000000000000000000000000000000000000000002751 210.0
HKD1_k127_4161548_7 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000004006 194.0
HKD1_k127_4161548_8 Polysaccharide deacetylase - - - 0.00000000000000000000000000002635 136.0
HKD1_k127_4161548_9 HxlR-like helix-turn-helix - - - 0.00000000000000003974 94.0
HKD1_k127_4163093_0 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 394.0
HKD1_k127_4163093_1 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin K00365 - 1.7.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003783 267.0
HKD1_k127_4163093_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000001974 223.0
HKD1_k127_4163093_3 META domain - - - 0.0000007867 57.0
HKD1_k127_4163093_4 nickel cation binding K04651 - - 0.0000009638 58.0
HKD1_k127_4163093_5 Hydrogenase maturation protease - - - 0.000003188 52.0
HKD1_k127_4168023_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000001458 217.0
HKD1_k127_4168023_1 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000004153 162.0
HKD1_k127_4168023_2 (Rhomboid) family - - - 0.00000000000000000000000000000002044 130.0
HKD1_k127_4168023_3 Glycosyl transferase K00728 - 2.4.1.109 0.0000000000000000000000000000006592 139.0
HKD1_k127_4168023_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000001258 125.0
HKD1_k127_4168023_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000007952 109.0
HKD1_k127_4168095_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 494.0
HKD1_k127_4168095_1 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 431.0
HKD1_k127_4168095_2 Aminotransferase class-V K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003826 284.0
HKD1_k127_4168095_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000003998 222.0
HKD1_k127_4168095_4 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000001244 141.0
HKD1_k127_4168095_5 PFAM penicillin-binding protein transpeptidase K05364 - - 0.00000000000000000004218 91.0
HKD1_k127_4168095_6 Reverse transcriptase-like K02226,K22316 - 3.1.26.4,3.1.3.73 0.000000000000000000502 98.0
HKD1_k127_4177613_0 PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 371.0
HKD1_k127_4177613_1 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000005044 240.0
HKD1_k127_4177613_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000003822 214.0
HKD1_k127_4177613_3 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000001818 179.0
HKD1_k127_4177613_4 lipoyl(octanoyl) transferase activity K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.00000000000000000000000000000000000000000001849 175.0
HKD1_k127_4177613_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000001426 99.0
HKD1_k127_4177613_6 Domain of unknown function (DU1801) - - - 0.000000000000006484 80.0
HKD1_k127_4180322_0 HAD-superfamily hydrolase, subfamily IA - - - 0.0000000000000000000000000000000000000000000000002485 195.0
HKD1_k127_4180322_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - - 0.00000000000000000000000001183 121.0
HKD1_k127_4180322_2 PFAM Phospholipid glycerol acyltransferase - - - 0.0000000000000000001465 103.0
HKD1_k127_4196045_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 6.915e-201 646.0
HKD1_k127_4196045_1 Cysteine synthase K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 498.0
HKD1_k127_4196045_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008323 435.0
HKD1_k127_4196045_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 371.0
HKD1_k127_4196045_4 Belongs to the MenA family. Type 1 subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 323.0
HKD1_k127_4196045_5 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000003378 64.0
HKD1_k127_4245963_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 436.0
HKD1_k127_4245963_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 319.0
HKD1_k127_4245963_2 Cytochrome c oxidase caa3-type, assembly factor CtaG-related K02351,K07245 - - 0.000000000000000000000000000000000000000000000009669 193.0
HKD1_k127_4245963_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000572 142.0
HKD1_k127_4245963_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000004896 78.0
HKD1_k127_4245963_5 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.00008328 46.0
HKD1_k127_4262282_0 Acylphosphatase K04656 - - 5.116e-259 821.0
HKD1_k127_4262282_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 2.855e-257 803.0
HKD1_k127_4262282_10 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000005236 151.0
HKD1_k127_4262282_11 Hydrogenase maturation protease - - - 0.0000000000000000000000000001141 121.0
HKD1_k127_4262282_12 Hydrogenase expression formation protein K04653 - - 0.000000000000000000000001346 114.0
HKD1_k127_4262282_13 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000207 98.0
HKD1_k127_4262282_14 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000003513 86.0
HKD1_k127_4262282_15 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000001168 89.0
HKD1_k127_4262282_2 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 578.0
HKD1_k127_4262282_3 TIGRFAM hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 439.0
HKD1_k127_4262282_4 pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 391.0
HKD1_k127_4262282_5 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 355.0
HKD1_k127_4262282_6 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009143 292.0
HKD1_k127_4262282_7 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006739 273.0
HKD1_k127_4262282_8 TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.000000000000000000000000000000000000000000000000000000004045 210.0
HKD1_k127_4262282_9 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.00000000000000000000000000000000000000000003224 168.0
HKD1_k127_4282120_0 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 377.0
HKD1_k127_4282120_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000008066 222.0
HKD1_k127_4282120_2 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000001677 143.0
HKD1_k127_4282120_3 Phospholipid methyltransferase - - - 0.0000000000000142 82.0
HKD1_k127_4282120_4 - - - - 0.000009598 50.0
HKD1_k127_4293533_0 carboxylic acid catabolic process K18334 - 4.2.1.68 5.295e-211 664.0
HKD1_k127_4293533_1 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 433.0
HKD1_k127_4293533_2 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 399.0
HKD1_k127_4293533_3 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 349.0
HKD1_k127_4293533_4 Amidohydrolase K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 314.0
HKD1_k127_4293533_5 gntR family K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000106 239.0
HKD1_k127_4293533_6 KR domain - - - 0.000000000007917 76.0
HKD1_k127_4295762_0 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000061 207.0
HKD1_k127_4295762_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000003444 215.0
HKD1_k127_4295762_2 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000003748 172.0
HKD1_k127_4298683_0 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) - - - 0.00000000000000000000000000000003388 144.0
HKD1_k127_4298683_1 Histidine kinase - - - 0.0000000000000000000002678 112.0
HKD1_k127_4298683_2 NUDIX domain K08310 - 3.6.1.67 0.00000000000001085 81.0
HKD1_k127_4315064_0 Adenylate K01768 - 4.6.1.1 3.837e-215 706.0
HKD1_k127_4315064_1 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 351.0
HKD1_k127_4315064_2 peptidase K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 348.0
HKD1_k127_4315064_3 Mur ligase middle domain K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 336.0
HKD1_k127_4315064_4 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000004542 136.0
HKD1_k127_4334821_0 4-Hydroxyphenylpyruvate dioxygenase K00457,K16421 GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 479.0
HKD1_k127_4334821_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 334.0
HKD1_k127_4334821_10 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000009628 85.0
HKD1_k127_4334821_11 - - - - 0.000009357 57.0
HKD1_k127_4334821_2 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000003181 253.0
HKD1_k127_4334821_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000001006 159.0
HKD1_k127_4334821_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000001223 121.0
HKD1_k127_4334821_5 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000003117 119.0
HKD1_k127_4334821_7 belongs to the sigma-70 factor family, ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000001572 108.0
HKD1_k127_4334821_9 PAP2 superfamily - - - 0.00000000000000006098 83.0
HKD1_k127_4348621_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 460.0
HKD1_k127_4348621_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002039 258.0
HKD1_k127_4348621_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000145 186.0
HKD1_k127_4348621_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000003378 181.0
HKD1_k127_4348621_4 Luciferase-like monooxygenase - - - 0.00000001738 62.0
HKD1_k127_4478165_0 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 338.0
HKD1_k127_4478165_1 Binding-protein-dependent transport system inner membrane component K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001942 284.0
HKD1_k127_4478165_2 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000008258 171.0
HKD1_k127_4478165_3 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000112 148.0
HKD1_k127_4478165_4 PFAM Peptidase C26 K07010 - - 0.00000000000000000000000000000003319 144.0
HKD1_k127_4478165_5 ABC transporter substrate-binding protein K02030,K02424,K17073 - - 0.000000002502 64.0
HKD1_k127_454632_0 Belongs to the proline racemase family K01777,K12658 - 5.1.1.4,5.1.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 501.0
HKD1_k127_454632_1 ATPases associated with a variety of cellular activities K09812 GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001997 276.0
HKD1_k127_454632_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000006207 290.0
HKD1_k127_454632_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000001477 188.0
HKD1_k127_454632_4 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.00000000000000000000000000000000002163 158.0
HKD1_k127_454632_5 Acetyltransferase (GNAT) family - - - 0.000000001987 64.0
HKD1_k127_4732008_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 8.509e-224 714.0
HKD1_k127_4732008_1 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 527.0
HKD1_k127_4732008_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 317.0
HKD1_k127_4732008_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000004118 248.0
HKD1_k127_4732008_4 Colicin V production protein - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944 - 0.00000000000000000000000000000000000000000000000000008179 202.0
HKD1_k127_4732008_5 ABC-2 family transporter protein K01421 - - 0.0000000000000000000004675 103.0
HKD1_k127_4732008_6 - - - - 0.00000002779 66.0
HKD1_k127_4736292_0 Protein of unknown function (DUF2652) - - - 0.000000000000000000000000000000000000000000000000000000000000000002312 244.0
HKD1_k127_4736292_1 Bacterial-like globin K06886 - - 0.000000000000004717 78.0
HKD1_k127_4736292_2 Acetyltransferase (GNAT) domain - - - 0.000004661 55.0
HKD1_k127_4859622_0 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 604.0
HKD1_k127_4859622_1 Ferritin-like domain K22336 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000006659 202.0
HKD1_k127_4859622_2 pfam nudix - - - 0.0000000000000000000000000000000000000000000000000004794 188.0
HKD1_k127_4859622_3 - - - - 0.00000000000000000000000000000000000000000000001137 188.0
HKD1_k127_4859622_4 Phenazine biosynthesis-like protein - - - 0.0000000000000000009147 94.0
HKD1_k127_4906800_0 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 373.0
HKD1_k127_4906800_1 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 343.0
HKD1_k127_4906800_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000003938 155.0
HKD1_k127_4906800_3 phosphorelay sensor kinase activity K03406,K07673,K07675 - 2.7.13.3 0.0000000000000000000000001386 123.0
HKD1_k127_4906800_4 Multicopper oxidase - - - 0.000000000000008306 76.0
HKD1_k127_4950558_0 Major Facilitator Superfamily - - - 3.282e-203 647.0
HKD1_k127_4950558_1 Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000001926 225.0
HKD1_k127_4950558_2 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000007364 112.0
HKD1_k127_4960516_0 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 449.0
HKD1_k127_4960516_1 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 387.0
HKD1_k127_4960516_2 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002462 301.0
HKD1_k127_4960516_3 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005218 284.0
HKD1_k127_4960516_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000001583 96.0
HKD1_k127_4960516_5 DNA ligase K01971 - 6.5.1.1 0.000001225 60.0
HKD1_k127_5018760_0 ABC transporter, transmembrane region K06147 - - 6.901e-265 838.0
HKD1_k127_5018760_1 ABC transporter transmembrane region K06147 - - 3.436e-208 662.0
HKD1_k127_5018760_10 pfam nudix K01515 - 3.6.1.13 0.00000000000000000000000000000000000001514 153.0
HKD1_k127_5018760_11 aminopeptidase N - - - 0.000000000000000000000000000000231 142.0
HKD1_k127_5018760_12 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189 0.0000000000000000000002696 109.0
HKD1_k127_5018760_13 - - - - 0.0000000000000000000009871 106.0
HKD1_k127_5018760_14 Tetratricopeptide repeat - - - 0.000000000000000007083 88.0
HKD1_k127_5018760_15 integral membrane protein - - - 0.000000000000002486 88.0
HKD1_k127_5018760_16 Iron dependent repressor, N-terminal DNA binding domain - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000003321 64.0
HKD1_k127_5018760_2 ATPases associated with a variety of cellular activities K10112,K10195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 448.0
HKD1_k127_5018760_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 408.0
HKD1_k127_5018760_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 359.0
HKD1_k127_5018760_5 FAD dependent oxidoreductase K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 372.0
HKD1_k127_5018760_6 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 357.0
HKD1_k127_5018760_7 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004032 253.0
HKD1_k127_5018760_8 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000003424 208.0
HKD1_k127_5018760_9 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000003694 171.0
HKD1_k127_5026777_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 351.0
HKD1_k127_5026777_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002586 295.0
HKD1_k127_5026777_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000009051 138.0
HKD1_k127_5026777_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.00000000000000000000000003328 114.0
HKD1_k127_5026777_4 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335,K05587 - 1.6.5.3 0.000000000000000001146 91.0
HKD1_k127_5026777_5 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.00000000001408 73.0
HKD1_k127_5072107_0 DinB family - - - 0.00000000000000000000000000001169 124.0
HKD1_k127_5072107_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0004845 52.0
HKD1_k127_508868_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 424.0
HKD1_k127_508868_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 335.0
HKD1_k127_508868_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000001322 214.0
HKD1_k127_508868_3 Lysyl oxidase - - - 0.000000000000000002143 100.0
HKD1_k127_508868_4 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000009472 88.0
HKD1_k127_508868_5 domain, Protein - - - 0.000233 54.0
HKD1_k127_5110736_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system - - - 3.546e-255 807.0
HKD1_k127_5110736_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 3.06e-218 682.0
HKD1_k127_5110736_10 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000001851 191.0
HKD1_k127_5110736_13 Pfam:Pyridox_oxidase - - - 0.000000000000000000001664 107.0
HKD1_k127_5110736_14 Lytic transglycolase K03642 - - 0.00000000000000002187 93.0
HKD1_k127_5110736_15 SPTR D1CGX5 Response regulator receiver protein - - - 0.00000000000002281 79.0
HKD1_k127_5110736_16 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000001047 76.0
HKD1_k127_5110736_2 Potassium-transporting ATPase A subunit K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 621.0
HKD1_k127_5110736_3 COG COG0531 Amino acid transporters Amino acid transport and metabolism - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 449.0
HKD1_k127_5110736_4 Osmosensitive K+ channel His kinase sensor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 316.0
HKD1_k127_5110736_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000185 291.0
HKD1_k127_5110736_6 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 274.0
HKD1_k127_5110736_7 response regulator, receiver K02483,K07667 - - 0.0000000000000000000000000000000000000000000000000000000008505 215.0
HKD1_k127_5110736_8 PFAM transferase hexapeptide repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000005471 205.0
HKD1_k127_5110736_9 Cupin superfamily (DUF985) K09705 - - 0.00000000000000000000000000000000000000000000000000004964 192.0
HKD1_k127_5123333_0 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 447.0
HKD1_k127_5123333_1 ResB-like family K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 311.0
HKD1_k127_5123333_2 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 301.0
HKD1_k127_5123333_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000005219 220.0
HKD1_k127_5123333_4 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000002199 165.0
HKD1_k127_5166099_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 436.0
HKD1_k127_5166099_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 394.0
HKD1_k127_5166099_2 SMART Nucleotide binding protein, PINc - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 303.0
HKD1_k127_5166099_3 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000004538 244.0
HKD1_k127_5169206_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.247e-288 907.0
HKD1_k127_5169206_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 7.38e-262 831.0
HKD1_k127_5169206_10 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005142 267.0
HKD1_k127_5169206_11 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000591 249.0
HKD1_k127_5169206_12 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000006251 247.0
HKD1_k127_5169206_13 transferase K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000003441 236.0
HKD1_k127_5169206_14 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000003654 189.0
HKD1_k127_5169206_15 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000001387 188.0
HKD1_k127_5169206_16 Cof-like hydrolase - - - 0.000000000000000000000000000000000004243 153.0
HKD1_k127_5169206_17 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000002397 119.0
HKD1_k127_5169206_18 Binds the 23S rRNA K02909 - - 0.000000000000000000000001205 105.0
HKD1_k127_5169206_19 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000004324 106.0
HKD1_k127_5169206_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.433e-212 686.0
HKD1_k127_5169206_20 thiolester hydrolase activity K03186 - 2.5.1.129 0.000000000000000000199 97.0
HKD1_k127_5169206_21 Protein of unknown function (DUF1294) - - - 0.000000000000000805 80.0
HKD1_k127_5169206_22 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000003889 81.0
HKD1_k127_5169206_23 Cytochrome C biogenesis protein K05516 - - 0.000000000003289 76.0
HKD1_k127_5169206_24 DNA alkylation repair enzyme - - - 0.0000000007088 70.0
HKD1_k127_5169206_25 Coiled-coil domain containing 17 - - - 0.0003014 47.0
HKD1_k127_5169206_26 Cbs domain - - - 0.0009008 48.0
HKD1_k127_5169206_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 496.0
HKD1_k127_5169206_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 418.0
HKD1_k127_5169206_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 384.0
HKD1_k127_5169206_6 Arsenical pump membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 364.0
HKD1_k127_5169206_7 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 349.0
HKD1_k127_5169206_8 Sporulation initiation inhibitor protein Soj K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 301.0
HKD1_k127_5169206_9 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003718 278.0
HKD1_k127_5178447_0 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 447.0
HKD1_k127_5178447_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 434.0
HKD1_k127_5178447_2 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 354.0
HKD1_k127_5178447_3 ROK family - - - 0.00000000000000000000000000000000000007853 158.0
HKD1_k127_5178447_4 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.000000000000000000000000009112 128.0
HKD1_k127_5233902_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.606e-262 827.0
HKD1_k127_5233902_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 6.684e-196 625.0
HKD1_k127_5233902_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000002872 184.0
HKD1_k127_5233902_11 Rieske-like [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000794 171.0
HKD1_k127_5233902_12 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000003254 152.0
HKD1_k127_5233902_13 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.000000000000000000000000000000002739 148.0
HKD1_k127_5233902_14 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000003924 126.0
HKD1_k127_5233902_15 PFAM Metallophosphoesterase K01090 - 3.1.3.16 0.0000000000000000000000000008071 128.0
HKD1_k127_5233902_16 Glucose-6-phosphate dehydrogenase subunit - - - 0.000000000000000000000007878 117.0
HKD1_k127_5233902_17 AAA domain - - - 0.0000000001733 74.0
HKD1_k127_5233902_18 PIN domain - - - 0.0000001011 60.0
HKD1_k127_5233902_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 443.0
HKD1_k127_5233902_3 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 424.0
HKD1_k127_5233902_4 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 392.0
HKD1_k127_5233902_5 DNA photolyase domain protein K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 402.0
HKD1_k127_5233902_6 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 342.0
HKD1_k127_5233902_7 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000171 241.0
HKD1_k127_5233902_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000002929 202.0
HKD1_k127_5233902_9 galactose-6-phosphate isomerase activity K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000008496 179.0
HKD1_k127_5238752_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 3.218e-255 822.0
HKD1_k127_5238752_1 GMC oxidoreductase - - - 7.958e-248 781.0
HKD1_k127_5238752_10 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001138 281.0
HKD1_k127_5238752_11 Branched-chain amino acid transport system / permease component K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009629 284.0
HKD1_k127_5238752_12 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000008002 274.0
HKD1_k127_5238752_13 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001561 275.0
HKD1_k127_5238752_14 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000001818 224.0
HKD1_k127_5238752_15 UTRA K03710 - - 0.000000000000000000000000000000000000000000000000000004108 212.0
HKD1_k127_5238752_16 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000185 186.0
HKD1_k127_5238752_17 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000004996 183.0
HKD1_k127_5238752_18 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000002212 190.0
HKD1_k127_5238752_19 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000003847 122.0
HKD1_k127_5238752_2 ABC-type sugar transport system, ATPase component K10441 - 3.6.3.17 1.751e-196 626.0
HKD1_k127_5238752_20 - - - - 0.000000000000000000001429 110.0
HKD1_k127_5238752_21 - - - - 0.00000000001785 78.0
HKD1_k127_5238752_22 - - - - 0.000000000145 69.0
HKD1_k127_5238752_23 SIS domain - - - 0.00000000062 64.0
HKD1_k127_5238752_3 Belongs to the aldehyde dehydrogenase family K00141 - 1.2.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 517.0
HKD1_k127_5238752_4 AP endonuclease family 2 C terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 486.0
HKD1_k127_5238752_5 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 480.0
HKD1_k127_5238752_6 aerobic electron transport chain K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 455.0
HKD1_k127_5238752_7 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 343.0
HKD1_k127_5238752_8 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 333.0
HKD1_k127_5238752_9 Cytochrome BD ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 312.0
HKD1_k127_52404_0 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001549 222.0
HKD1_k127_52404_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000109 124.0
HKD1_k127_52404_2 ECF sigma factor K03088 - - 0.00000000000000000000007462 106.0
HKD1_k127_5250814_0 Pyridine nucleotide-disulphide oxidoreductase - - - 2.033e-232 726.0
HKD1_k127_5250814_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 513.0
HKD1_k127_5250814_10 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.0003713 51.0
HKD1_k127_5250814_2 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 397.0
HKD1_k127_5250814_3 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 323.0
HKD1_k127_5250814_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000413 244.0
HKD1_k127_5250814_5 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000007334 172.0
HKD1_k127_5250814_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000003915 96.0
HKD1_k127_5250814_7 PFAM Cold-shock protein DNA-binding K03704 - - 0.00000000004076 68.0
HKD1_k127_5250814_8 Bacterial regulatory proteins, tetR family - - - 0.00000000005878 73.0
HKD1_k127_5250814_9 Bacterial regulatory proteins, tetR family - - - 0.000001215 59.0
HKD1_k127_5253761_0 PhoD-like phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 612.0
HKD1_k127_5253761_1 ATP dependent DNA ligase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 556.0
HKD1_k127_5253761_2 DNA primase, small subunit K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 300.0
HKD1_k127_5253761_3 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007396 256.0
HKD1_k127_5265033_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 7.731e-275 855.0
HKD1_k127_5265033_1 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 400.0
HKD1_k127_5265033_2 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 375.0
HKD1_k127_5265033_3 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 297.0
HKD1_k127_5265033_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000001923 108.0
HKD1_k127_5341127_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 469.0
HKD1_k127_5341127_1 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 325.0
HKD1_k127_5341127_10 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.000000000000000007288 98.0
HKD1_k127_5341127_11 - - - - 0.00003168 53.0
HKD1_k127_5341127_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 287.0
HKD1_k127_5341127_3 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001636 275.0
HKD1_k127_5341127_4 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000001826 242.0
HKD1_k127_5341127_5 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000004479 160.0
HKD1_k127_5341127_6 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000007651 154.0
HKD1_k127_5341127_7 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000008556 111.0
HKD1_k127_5341127_8 Major Facilitator Superfamily - - - 0.0000000000000000000152 105.0
HKD1_k127_5341127_9 Sigma-70, region 4 K03088 - - 0.000000000000000006473 91.0
HKD1_k127_5406873_0 PFAM Dak kinase K05878 - 2.7.1.121 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 479.0
HKD1_k127_5406873_1 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000005817 267.0
HKD1_k127_5406873_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000001078 66.0
HKD1_k127_5406873_11 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000003494 73.0
HKD1_k127_5406873_12 heat shock protein binding - - - 0.00001562 55.0
HKD1_k127_5406873_2 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005549 250.0
HKD1_k127_5406873_3 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000003613 233.0
HKD1_k127_5406873_4 Dak2 K05879 - 2.7.1.121 0.0000000000000000000000000000000000000000000000000000000000000567 221.0
HKD1_k127_5406873_5 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000001833 202.0
HKD1_k127_5406873_6 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000004953 169.0
HKD1_k127_5406873_7 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000008526 176.0
HKD1_k127_5406873_8 Response regulator receiver - - - 0.000000000000000000000000000000007562 140.0
HKD1_k127_5406873_9 DNA binding domain - - - 0.000000000000000000000000003995 117.0
HKD1_k127_5413486_0 Cystathionine beta-lyases cystathionine K01739,K21173 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 468.0
HKD1_k127_5413486_1 bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 317.0
HKD1_k127_5413486_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001026 263.0
HKD1_k127_5413486_3 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000003451 151.0
HKD1_k127_5413486_4 HAD superfamily, subfamily IIIB (Acid phosphatase) - - - 0.0000000000000000000009118 95.0
HKD1_k127_5413486_5 Sigma-70 region 2 K03088 - - 0.0000000000000000005554 94.0
HKD1_k127_5413486_6 Glyoxalase-like domain - - - 0.000000000000009918 79.0
HKD1_k127_5413486_7 Uncharacterized protein conserved in bacteria (DUF2200) - - - 0.00000000002221 67.0
HKD1_k127_5413486_8 - - - - 0.00000001402 61.0
HKD1_k127_5517970_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 396.0
HKD1_k127_5517970_1 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005655 254.0
HKD1_k127_5517970_2 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000001026 226.0
HKD1_k127_5517970_3 PFAM GCN5-related N-acetyltransferase K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000006925 203.0
HKD1_k127_5517970_4 TRANSCRIPTIONal - - - 0.00000000000000000000000000000000000000000000000004244 198.0
HKD1_k127_5517970_5 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000034 191.0
HKD1_k127_559531_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1306.0
HKD1_k127_559531_1 Acetokinase family K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 394.0
HKD1_k127_559531_2 Phage shock protein A K03969 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000001328 102.0
HKD1_k127_5598236_0 Type II/IV secretion system protein K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 548.0
HKD1_k127_5598236_1 UDP binding domain K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 403.0
HKD1_k127_5598236_10 Peptidylprolyl isomerase K01802,K03769 - 5.2.1.8 0.0000000000002081 83.0
HKD1_k127_5598236_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006198 283.0
HKD1_k127_5598236_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001405 296.0
HKD1_k127_5598236_4 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001996 274.0
HKD1_k127_5598236_5 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000002877 269.0
HKD1_k127_5598236_6 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000004797 223.0
HKD1_k127_5598236_7 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000339 180.0
HKD1_k127_5598236_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000185 168.0
HKD1_k127_5598236_9 cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000005495 135.0
HKD1_k127_56077_0 PFAM ABC transporter related K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 571.0
HKD1_k127_56077_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 542.0
HKD1_k127_56077_10 acetyltransferase - - - 0.00000000000000000000001642 117.0
HKD1_k127_56077_11 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000005692 105.0
HKD1_k127_56077_12 Acetyltransferase (GNAT) domain - - - 0.000000000000001823 87.0
HKD1_k127_56077_2 Aminotransferase K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 490.0
HKD1_k127_56077_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 469.0
HKD1_k127_56077_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 456.0
HKD1_k127_56077_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004279 271.0
HKD1_k127_56077_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001134 269.0
HKD1_k127_56077_7 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000003901 166.0
HKD1_k127_56077_8 CoA-binding protein K06929 - - 0.000000000000000000000000000000103 138.0
HKD1_k127_56077_9 PFAM basic membrane lipoprotein K07335 - - 0.0000000000000000000000000000005449 132.0
HKD1_k127_5616606_0 elongation factor Tu domain 2 protein K06207 - - 1.081e-219 698.0
HKD1_k127_5616606_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 378.0
HKD1_k127_5616606_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 371.0
HKD1_k127_5616606_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001218 273.0
HKD1_k127_5616606_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000009434 191.0
HKD1_k127_5616606_5 sulfurtransferase activity K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000671 163.0
HKD1_k127_5616606_6 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00003558 54.0
HKD1_k127_5670575_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000009303 259.0
HKD1_k127_5670575_1 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000004583 244.0
HKD1_k127_5670575_2 BioY protein K03523 - - 0.00000000000000000000000000000000000000000004697 169.0
HKD1_k127_5670575_3 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000608 141.0
HKD1_k127_5670575_4 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000000000000000000000007388 108.0
HKD1_k127_5670575_5 Cysteine-rich secretory protein family - - - 0.0000000000000000001131 101.0
HKD1_k127_5693750_0 Dehydrogenase K00248,K00249,K20035 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0052890,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.3.8.1,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 518.0
HKD1_k127_5693750_1 PFAM oxidoreductase molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 456.0
HKD1_k127_5693750_2 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 348.0
HKD1_k127_5693750_3 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005165 301.0
HKD1_k127_5693750_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000001517 150.0
HKD1_k127_5829698_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 501.0
HKD1_k127_5829698_1 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005994 261.0
HKD1_k127_5829698_2 DoxX K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000000000000000000000002266 235.0
HKD1_k127_5829698_3 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000137 225.0
HKD1_k127_5829698_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000002928 220.0
HKD1_k127_5829698_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000008499 190.0
HKD1_k127_5829698_6 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.000000000000000000000000000000001178 143.0
HKD1_k127_5829698_7 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000001653 102.0
HKD1_k127_5843344_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 489.0
HKD1_k127_5843344_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 341.0
HKD1_k127_5843344_2 TIGRFAM Methylglyoxal synthase K01734 - 4.2.3.3 0.000000000000000000000000000000000000000000000000000000000004078 218.0
HKD1_k127_5853951_0 Belongs to the ABC transporter superfamily K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 423.0
HKD1_k127_5853951_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 423.0
HKD1_k127_5853951_2 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000001303 160.0
HKD1_k127_5853951_3 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.000000000000000000000000000001836 122.0
HKD1_k127_5863979_0 Uncharacterised protein family (UPF0261) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 518.0
HKD1_k127_5863979_1 Phosphoenolpyruvate hydrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 448.0
HKD1_k127_5863979_2 Domain of unknown function (DUF1905) - - - 0.00000000000000000000000000000000008353 141.0
HKD1_k127_5863979_3 - - - - 0.0000000000005012 75.0
HKD1_k127_5863979_4 pyridoxamine 5-phosphate - - - 0.0003959 49.0
HKD1_k127_5949619_0 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 564.0
HKD1_k127_5949619_1 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 525.0
HKD1_k127_5949619_2 DinB family - - - 0.000000000000000000000000000000000003766 142.0
HKD1_k127_5985130_0 tRNA (guanine-N7-)-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 372.0
HKD1_k127_5985130_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000003754 175.0
HKD1_k127_6038872_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 598.0
HKD1_k127_6038872_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 404.0
HKD1_k127_6038872_10 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000003324 116.0
HKD1_k127_6038872_11 Carbohydrate kinase - - - 0.00000005321 66.0
HKD1_k127_6038872_12 - - - - 0.0005701 51.0
HKD1_k127_6038872_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000739 225.0
HKD1_k127_6038872_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000624 227.0
HKD1_k127_6038872_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 0.000000000000000000000000000000000000000000000000000000001257 214.0
HKD1_k127_6038872_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000001866 184.0
HKD1_k127_6038872_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000007442 171.0
HKD1_k127_6038872_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000002333 169.0
HKD1_k127_6038872_8 PFAM GDSL-like Lipase Acylhydrolase - - - 0.000000000000000000000000000000000005383 145.0
HKD1_k127_6038872_9 PFAM YbbR family protein - - - 0.0000000000000000000000000003314 129.0
HKD1_k127_6048479_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 483.0
HKD1_k127_6048479_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002074 285.0
HKD1_k127_6048479_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000003056 274.0
HKD1_k127_6048479_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000008946 224.0
HKD1_k127_6048479_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000001038 149.0
HKD1_k127_6048479_5 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000005273 110.0
HKD1_k127_6048479_6 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000008502 97.0
HKD1_k127_6048479_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000000001736 98.0
HKD1_k127_6048479_8 Belongs to the UPF0102 family K07460 - - 0.0000004516 59.0
HKD1_k127_6048479_9 Protein of unknown function (DUF3352) - - - 0.0006784 52.0
HKD1_k127_6059211_0 ABC transporter K01990,K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 332.0
HKD1_k127_6059211_1 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000001518 243.0
HKD1_k127_6059211_2 Abc-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000003402 224.0
HKD1_k127_6059211_3 BetI-type transcriptional repressor, C-terminal - - - 0.00000000000000000000000002295 119.0
HKD1_k127_605937_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 637.0
HKD1_k127_605937_1 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005968 428.0
HKD1_k127_605937_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 327.0
HKD1_k127_605937_3 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000602 234.0
HKD1_k127_605937_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000006273 100.0
HKD1_k127_605937_5 Histidine kinase - - - 0.0000002365 61.0
HKD1_k127_6064872_0 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 632.0
HKD1_k127_6064872_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009717 435.0
HKD1_k127_6064872_2 SpoIIAA-like - - - 0.00000000006247 66.0
HKD1_k127_6064872_3 lysyltransferase activity - - - 0.000001665 54.0
HKD1_k127_6064872_4 transcriptional regulator - - - 0.00003015 56.0
HKD1_k127_6077675_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 466.0
HKD1_k127_6077675_1 Dehydrogenase E1 component K00166,K21416 - 1.2.4.4 0.00000000000000000000000000000000000000000000002845 179.0
HKD1_k127_6077675_2 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000007448 135.0
HKD1_k127_6077675_3 light absorption - - - 0.00000000000000001937 92.0
HKD1_k127_608454_0 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 334.0
HKD1_k127_608454_1 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000001604 125.0
HKD1_k127_608454_2 Bacterial protein of unknown function (DUF885) - - - 0.0000000006055 70.0
HKD1_k127_608454_3 - - - - 0.0006222 52.0
HKD1_k127_6101008_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.817e-267 833.0
HKD1_k127_6101008_1 Heat shock 70 kDa protein K04043 - - 2.563e-258 811.0
HKD1_k127_6101008_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002431 260.0
HKD1_k127_6101008_3 Elongator protein 3, MiaB family, Radical SAM - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000003151 242.0
HKD1_k127_6101008_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000007423 133.0
HKD1_k127_6101008_6 Binds directly to 16S ribosomal RNA K02968 - - 0.000009357 57.0
HKD1_k127_6112420_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 4.011e-219 710.0
HKD1_k127_6112420_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 601.0
HKD1_k127_6112420_10 Sugar (and other) transporter - GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008144,GO:0008150,GO:0009405,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0051704,GO:0055085,GO:0071944 - 0.000000000000000000000000000003577 137.0
HKD1_k127_6112420_11 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000005399 118.0
HKD1_k127_6112420_12 CDP-alcohol phosphatidyltransferase K00995,K00999 GO:0003674,GO:0003824,GO:0003881,GO:0003882,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.11,2.7.8.5 0.000000000000000000000000007129 118.0
HKD1_k127_6112420_13 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000006155 111.0
HKD1_k127_6112420_14 Bacterial lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.000000000000000000000128 113.0
HKD1_k127_6112420_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000001133 96.0
HKD1_k127_6112420_16 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000521 91.0
HKD1_k127_6112420_17 transcriptional K03892 - - 0.000000000005232 70.0
HKD1_k127_6112420_2 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 505.0
HKD1_k127_6112420_3 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 493.0
HKD1_k127_6112420_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 359.0
HKD1_k127_6112420_5 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 333.0
HKD1_k127_6112420_6 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 318.0
HKD1_k127_6112420_7 Mediates influx of magnesium ions K03284 GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - 0.00000000000000000000000000000000000000000000786 178.0
HKD1_k127_6112420_8 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000008971 149.0
HKD1_k127_6112420_9 Kdo2-lipid A biosynthetic process K02517,K22311 - 2.3.1.241,2.3.1.265 0.0000000000000000000000000000000002238 150.0
HKD1_k127_6118428_0 alcohol dehydrogenase K00008,K08322 - 1.1.1.14,1.1.1.380 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 518.0
HKD1_k127_6118428_1 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 484.0
HKD1_k127_6118428_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 441.0
HKD1_k127_6118428_3 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 391.0
HKD1_k127_6118428_4 Short-chain dehydrogenase reductase sdr K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000005138 231.0
HKD1_k127_6118766_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.288e-199 641.0
HKD1_k127_6118766_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 576.0
HKD1_k127_6118766_2 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 506.0
HKD1_k127_6118766_3 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 497.0
HKD1_k127_6118766_4 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 374.0
HKD1_k127_6118766_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000113 218.0
HKD1_k127_6118766_6 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000001781 165.0
HKD1_k127_6118766_7 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000004128 125.0
HKD1_k127_6118766_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000001528 116.0
HKD1_k127_6118766_9 Protein of unknown function (DUF448) K02600,K07742 - - 0.000000000000000001789 96.0
HKD1_k127_6165581_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 369.0
HKD1_k127_6165581_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 355.0
HKD1_k127_6165581_10 Sigma-70, region 4 K03088 - - 0.0000000000000002448 89.0
HKD1_k127_6165581_11 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000892 87.0
HKD1_k127_6165581_12 Glycoprotease family K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.0000000000002655 79.0
HKD1_k127_6165581_13 Adenylate cyclase K01768 - 4.6.1.1 0.000000002192 70.0
HKD1_k127_6165581_2 flavin adenine dinucleotide binding K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 311.0
HKD1_k127_6165581_3 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000005631 269.0
HKD1_k127_6165581_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000002198 209.0
HKD1_k127_6165581_5 Kelch motif - - - 0.00000000000000000000000000000000000000000000000000002021 207.0
HKD1_k127_6165581_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000162 175.0
HKD1_k127_6165581_7 Acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000007131 160.0
HKD1_k127_6165581_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000808 160.0
HKD1_k127_6165581_9 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000005011 151.0
HKD1_k127_6194391_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000002681 171.0
HKD1_k127_6194391_1 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.0000000000000000000000000000000000211 140.0
HKD1_k127_6217951_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1080.0
HKD1_k127_6217951_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.319e-211 669.0
HKD1_k127_6217951_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000263 64.0
HKD1_k127_6217951_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 458.0
HKD1_k127_6217951_3 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 389.0
HKD1_k127_6217951_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 330.0
HKD1_k127_6217951_5 DnaJ-class molecular chaperone with C-terminal Zn finger domain K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000002688 237.0
HKD1_k127_6217951_6 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000192 135.0
HKD1_k127_6217951_7 Including oxidative damage repair enzymes - - - 0.00000000000000000000000008807 115.0
HKD1_k127_6217951_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000008254 111.0
HKD1_k127_6217951_9 GTP binding - - - 0.000000000005303 77.0
HKD1_k127_6247796_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 614.0
HKD1_k127_6247796_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 594.0
HKD1_k127_6247796_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 484.0
HKD1_k127_6247796_3 Thermophilic metalloprotease (M29) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 381.0
HKD1_k127_6247796_4 Phosphatidylinositol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005933 269.0
HKD1_k127_6247796_5 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000000000000000000000000001201 182.0
HKD1_k127_6264530_0 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000008506 236.0
HKD1_k127_6264530_1 xylulokinase activity K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000003575 192.0
HKD1_k127_6273795_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 371.0
HKD1_k127_6273795_1 - - - - 0.000000000000000000000000000000000000000000000006497 189.0
HKD1_k127_6273795_2 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000003864 98.0
HKD1_k127_6273795_3 Secreted repeat of unknown function - - - 0.00000000000000003111 94.0
HKD1_k127_6273895_0 Glycine cleavage system P-protein K00283 - 1.4.4.2 4.41e-251 793.0
HKD1_k127_6273895_1 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 584.0
HKD1_k127_6273895_10 PFAM ATP-NAD AcoX kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005492 282.0
HKD1_k127_6273895_11 Transcriptional regulators of sugar metabolism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004066 267.0
HKD1_k127_6273895_12 Branched-chain amino acid ATP-binding cassette transporter K01995,K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007503 283.0
HKD1_k127_6273895_13 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001483 263.0
HKD1_k127_6273895_14 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000223 240.0
HKD1_k127_6273895_15 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000006235 203.0
HKD1_k127_6273895_16 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000008007 172.0
HKD1_k127_6273895_17 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000002192 162.0
HKD1_k127_6273895_19 cell redox homeostasis K02199 - - 0.00007088 48.0
HKD1_k127_6273895_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 368.0
HKD1_k127_6273895_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 368.0
HKD1_k127_6273895_4 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 331.0
HKD1_k127_6273895_5 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009869 331.0
HKD1_k127_6273895_6 Glutamine synthetase N-terminal domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 317.0
HKD1_k127_6273895_7 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 306.0
HKD1_k127_6273895_8 PFAM Acetamidase Formamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 304.0
HKD1_k127_6273895_9 Short-chain dehydrogenase reductase sdr K00059,K18009 - 1.1.1.100,1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 286.0
HKD1_k127_6297837_0 COG0608 Single-stranded DNA-specific exonuclease K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001087 284.0
HKD1_k127_6297837_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000317 205.0
HKD1_k127_6320172_0 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 335.0
HKD1_k127_6320172_1 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 327.0
HKD1_k127_6320172_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000006159 235.0
HKD1_k127_6320172_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000007031 235.0
HKD1_k127_6320172_4 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000002362 151.0
HKD1_k127_6320172_5 Cytidylate kinase-like family K00760 - 2.4.2.8 0.000000000000000000000000000000000008359 146.0
HKD1_k127_6320172_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000009957 105.0
HKD1_k127_6320172_7 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000001113 101.0
HKD1_k127_6439586_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 413.0
HKD1_k127_6439586_1 nuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 407.0
HKD1_k127_6439586_2 Acetylornithine deacetylase K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 334.0
HKD1_k127_6439586_3 dimethylargininase activity K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000001384 251.0
HKD1_k127_6439586_4 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000002829 185.0
HKD1_k127_6439586_5 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000009514 187.0
HKD1_k127_6439586_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000003734 143.0
HKD1_k127_6439586_7 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000002064 140.0
HKD1_k127_6439586_8 Cupin domain - - - 0.000000000000000000000000000006006 123.0
HKD1_k127_6521472_0 permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 343.0
HKD1_k127_6521472_1 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine - - - 0.000000000000000000000000000000000000000000000000000003026 200.0
HKD1_k127_6521472_2 Oxidoreductase molybdopterin binding domain - - - 0.0000000002501 68.0
HKD1_k127_6521472_3 - - - - 0.00002464 52.0
HKD1_k127_6534068_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 563.0
HKD1_k127_6534068_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 401.0
HKD1_k127_6534068_2 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000003272 241.0
HKD1_k127_6534068_3 PFAM NMT1 THI5 like domain protein K02051 - - 0.000000000000000000000000000000000000000000000000000000000000001364 233.0
HKD1_k127_6534068_4 Binding-protein-dependent transport system inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000007644 213.0
HKD1_k127_6534068_5 Domain of unknown function DUF11 - - - 0.0000000000000000000000000000000000000000000000000000009644 211.0
HKD1_k127_6534068_6 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000002042 191.0
HKD1_k127_6534068_7 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000003861 132.0
HKD1_k127_6583882_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 525.0
HKD1_k127_6583882_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K00823,K07250 - 2.6.1.19,2.6.1.22,4.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 501.0
HKD1_k127_6583882_10 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.00000000000000000000000000000000000000004714 168.0
HKD1_k127_6583882_11 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000000004822 156.0
HKD1_k127_6583882_12 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000001617 142.0
HKD1_k127_6583882_13 Ferric uptake regulator family K03711,K09825 - - 0.000000000000000000000541 111.0
HKD1_k127_6583882_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 391.0
HKD1_k127_6583882_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 392.0
HKD1_k127_6583882_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 341.0
HKD1_k127_6583882_5 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001134 258.0
HKD1_k127_6583882_6 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.00000000000000000000000000000000000000000000000000000000000000009644 234.0
HKD1_k127_6583882_7 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000489 226.0
HKD1_k127_6583882_8 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000000000000000001438 203.0
HKD1_k127_6583882_9 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000003636 188.0
HKD1_k127_672146_0 Putative glutamine amidotransferase K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 638.0
HKD1_k127_672146_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 387.0
HKD1_k127_672146_2 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 368.0
HKD1_k127_672146_3 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 318.0
HKD1_k127_672146_4 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001764 265.0
HKD1_k127_672146_5 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000002333 239.0
HKD1_k127_672146_6 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000003412 239.0
HKD1_k127_672146_7 nuclear chromosome segregation - - - 0.00000000000000000000000000000003778 145.0
HKD1_k127_672146_8 ABC-2 family transporter protein - - - 0.0000000000000000000000000000005631 138.0
HKD1_k127_6762520_0 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 519.0
HKD1_k127_6762520_1 TrkA-N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 435.0
HKD1_k127_6762520_2 PFAM alanine dehydrogenase PNT domain protein K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 405.0
HKD1_k127_6762520_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000009929 143.0
HKD1_k127_6762520_4 acetyltransferase - - - 0.0000000000000000000009095 106.0
HKD1_k127_6762520_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000003557 79.0
HKD1_k127_6762520_6 Cell wall-active antibiotics response 4TMS YvqF - - - 0.0000000052 65.0
HKD1_k127_6820776_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 1.689e-225 711.0
HKD1_k127_6820776_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 406.0
HKD1_k127_6820776_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 299.0
HKD1_k127_6820776_3 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000008964 244.0
HKD1_k127_6820776_4 ECF sigma factor K03088 - - 0.000000000000000000000000004993 119.0
HKD1_k127_6820776_5 -acetyltransferase - - - 0.00000000000000000000511 100.0
HKD1_k127_6820776_6 WD40-like Beta Propeller Repeat - - - 0.000001241 61.0
HKD1_k127_6839084_0 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 317.0
HKD1_k127_6839084_1 NAD synthase K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001394 284.0
HKD1_k127_6839084_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000238 253.0
HKD1_k127_6839084_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000000000000003032 218.0
HKD1_k127_689366_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 538.0
HKD1_k127_689366_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 312.0
HKD1_k127_689366_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 310.0
HKD1_k127_689366_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000362 162.0
HKD1_k127_689366_4 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000007434 122.0
HKD1_k127_689366_5 PFAM metallophosphoesterase - - - 0.00000000000000000004068 103.0
HKD1_k127_689366_6 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.0000000002246 68.0
HKD1_k127_689366_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.0002404 51.0
HKD1_k127_6941272_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000006737 243.0
HKD1_k127_6941272_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000138 198.0
HKD1_k127_6941272_2 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000003203 201.0
HKD1_k127_6941272_3 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.0000000000000000000000000000000000002091 155.0
HKD1_k127_6941272_4 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000000000000112 137.0
HKD1_k127_6941272_5 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.0000000000000000001332 96.0
HKD1_k127_6941272_6 Helix-turn-helix domain - - - 0.0001291 46.0
HKD1_k127_695389_0 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 436.0
HKD1_k127_695389_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 384.0
HKD1_k127_695389_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 356.0
HKD1_k127_695389_3 e3 binding domain K00627,K09699 - 2.3.1.12,2.3.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 331.0
HKD1_k127_695389_4 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 322.0
HKD1_k127_695389_5 Dehydrogenase E1 component K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000788 206.0
HKD1_k127_695389_6 transcriptional regulator - - - 0.00000007658 55.0
HKD1_k127_6958210_0 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 434.0
HKD1_k127_6958210_1 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 364.0
HKD1_k127_6958210_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009546 329.0
HKD1_k127_6958210_3 saccharopine dehydrogenase activity K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 317.0
HKD1_k127_6958210_4 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 317.0
HKD1_k127_6958210_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000003001 140.0
HKD1_k127_6958210_6 Response regulator receiver K07696 - - 0.0000000000000000000000000000002379 135.0
HKD1_k127_7034162_0 ABC transporter K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 441.0
HKD1_k127_7034162_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 389.0
HKD1_k127_7034162_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 316.0
HKD1_k127_7034162_3 Transport permease protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 297.0
HKD1_k127_7034162_4 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000005663 193.0
HKD1_k127_7034162_5 Methylates ribosomal protein L11 K02687 - - 0.00007501 53.0
HKD1_k127_7058844_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 451.0
HKD1_k127_7058844_1 Dak1_2 K07030 - - 0.000000000000000000000000000000000000000000002687 176.0
HKD1_k127_7058844_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000006471 165.0
HKD1_k127_7058844_3 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000003245 129.0
HKD1_k127_7058844_4 negative regulation of DNA recombination - - - 0.00000000000000000000008887 104.0
HKD1_k127_7101140_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 534.0
HKD1_k127_7101140_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 394.0
HKD1_k127_7101140_2 Penicillin-Binding Protein C-terminus Family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006991 296.0
HKD1_k127_7101140_3 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000009821 154.0
HKD1_k127_7101140_4 Colicin V production protein K03558 - - 0.000005759 57.0
HKD1_k127_7103960_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 546.0
HKD1_k127_7103960_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 466.0
HKD1_k127_7103960_10 DNA-templated transcription, initiation K03088 - - 0.000000000004183 77.0
HKD1_k127_7103960_11 Belongs to the UPF0354 family - - - 0.0000000002456 70.0
HKD1_k127_7103960_2 Extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 466.0
HKD1_k127_7103960_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001374 263.0
HKD1_k127_7103960_4 response to abiotic stimulus - - - 0.000000000000000000000000000000000000000000003828 173.0
HKD1_k127_7103960_5 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000009753 185.0
HKD1_k127_7103960_6 PFAM flavin reductase domain protein, FMN-binding K16048 - - 0.000000000000000000000000000000000002823 145.0
HKD1_k127_7103960_7 iron-sulfur cluster insertion protein erpA K15724 - - 0.0000000000000000000000000000001311 129.0
HKD1_k127_7103960_8 Alpha beta hydrolase - - - 0.00000000000000000000000000003368 129.0
HKD1_k127_7103960_9 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000004032 116.0
HKD1_k127_7204214_0 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 1.166e-280 919.0
HKD1_k127_7204214_1 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 512.0
HKD1_k127_7204214_10 - - - - 0.00000000000000000000000000001224 128.0
HKD1_k127_7204214_11 histidine kinase A domain protein K07636 - 2.7.13.3 0.00000000000000000000000000003789 126.0
HKD1_k127_7204214_12 - - - - 0.0000000003209 68.0
HKD1_k127_7204214_14 Transcriptional regulatory protein, C terminal - - - 0.0009203 49.0
HKD1_k127_7204214_2 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 487.0
HKD1_k127_7204214_3 TIGRFAM cysteine desulfurase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 389.0
HKD1_k127_7204214_4 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000064 276.0
HKD1_k127_7204214_5 amino acid - - - 0.00000000000000000000000000000000000000000000000000006193 208.0
HKD1_k127_7204214_6 PFAM photosystem I assembly BtpA K06971 - - 0.0000000000000000000000000000000000000000003373 175.0
HKD1_k127_7204214_7 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000001493 158.0
HKD1_k127_7204214_8 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000004016 149.0
HKD1_k127_7204214_9 Transcriptional regulator, deor family - - - 0.00000000000000000000000000000002916 138.0
HKD1_k127_7250594_0 Cell cycle protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 360.0
HKD1_k127_7250594_1 PFAM penicillin-binding protein transpeptidase K05364 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002371 289.0
HKD1_k127_7250594_2 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000002994 132.0
HKD1_k127_7250594_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000005813 100.0
HKD1_k127_7253239_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1145.0
HKD1_k127_7253239_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 306.0
HKD1_k127_7253239_2 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000002288 197.0
HKD1_k127_7253239_3 - K06039,K07092 - - 0.000000000000000000000000008776 117.0
HKD1_k127_7253239_4 Sulfurtransferase TusA - - - 0.0000000000000000000000005871 106.0
HKD1_k127_7253239_5 DsrE/DsrF-like family - - - 0.000000000000000000007853 98.0
HKD1_k127_7253239_6 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000004014 92.0
HKD1_k127_7253239_7 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000003663 81.0
HKD1_k127_7253239_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000009548 79.0
HKD1_k127_7253239_9 membrane - - - 0.000005475 57.0
HKD1_k127_7258276_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 0.0 1080.0
HKD1_k127_7258276_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006812 280.0
HKD1_k127_7258276_2 cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000000000000000000000000000001348 216.0
HKD1_k127_7258276_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000009463 115.0
HKD1_k127_7258276_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000002116 66.0
HKD1_k127_726463_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 344.0
HKD1_k127_726463_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 321.0
HKD1_k127_726463_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 306.0
HKD1_k127_726463_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000009148 264.0
HKD1_k127_726463_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000009953 243.0
HKD1_k127_726463_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000002891 207.0
HKD1_k127_726463_6 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000001297 138.0
HKD1_k127_726463_7 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000001572 126.0
HKD1_k127_7303176_0 ABC-type multidrug transport system ATPase component K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 305.0
HKD1_k127_7303176_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000006392 244.0
HKD1_k127_7303176_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000003293 208.0
HKD1_k127_7303176_3 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.0000000000000000000000000000000000000000000000000003736 202.0
HKD1_k127_7303176_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001057 85.0
HKD1_k127_7303176_5 - - - - 0.0008481 45.0
HKD1_k127_7307762_0 ABC transporter - - - 1.351e-270 841.0
HKD1_k127_7307762_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 476.0
HKD1_k127_7307762_10 phosphatase K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000009735 213.0
HKD1_k127_7307762_11 Methyltransferase domain - - - 0.000000000000000000000000000000000000000001622 164.0
HKD1_k127_7307762_12 Putative glycolipid-binding - - - 0.00000000000000000000000000000000000001028 152.0
HKD1_k127_7307762_13 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000001356 151.0
HKD1_k127_7307762_14 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000005693 145.0
HKD1_k127_7307762_15 - - - - 0.0005304 52.0
HKD1_k127_7307762_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 445.0
HKD1_k127_7307762_3 Fungal trichothecene efflux pump (TRI12) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 420.0
HKD1_k127_7307762_4 TIGRFAM Na H antiporter, bacterial form K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 364.0
HKD1_k127_7307762_5 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 338.0
HKD1_k127_7307762_6 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001885 295.0
HKD1_k127_7307762_7 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000001384 243.0
HKD1_k127_7307762_9 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004022 222.0
HKD1_k127_7409930_0 Histidine kinase-like ATPases K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005354 294.0
HKD1_k127_7409930_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000001748 129.0
HKD1_k127_7409930_2 PspC domain K03973 - - 0.0000000002019 73.0
HKD1_k127_7409930_3 - - - - 0.0002972 50.0
HKD1_k127_7461759_0 Serine threonine protein kinase involved in cell cycle control - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 313.0
HKD1_k127_7461759_1 PFAM HhH-GPD family protein - - - 0.00000000000000000000000000000000000000000000000002459 185.0
HKD1_k127_7461759_2 Protein of unknown function (DUF3037) - - - 0.00000000000000000000000000000000001737 143.0
HKD1_k127_7461759_3 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000004662 136.0
HKD1_k127_7461759_4 Psort location Cytoplasmic, score - - - 0.000000000000000000000000008583 115.0
HKD1_k127_7461759_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000006319 106.0
HKD1_k127_7461759_6 ATP-NAD kinase K19302 - 3.6.1.27 0.000000274 56.0
HKD1_k127_7461759_7 domain, Protein - - - 0.0002737 51.0
HKD1_k127_7482162_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.261e-228 738.0
HKD1_k127_7482162_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 614.0
HKD1_k127_7482162_2 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 581.0
HKD1_k127_7482162_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 379.0
HKD1_k127_7482162_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000002534 226.0
HKD1_k127_7482162_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000001673 121.0
HKD1_k127_7482162_6 KR domain - - - 0.00000000000001774 74.0
HKD1_k127_7506002_0 Cys/Met metabolism PLP-dependent enzyme K11325 - - 0.0000000000000000000000000000000000000000000000001219 187.0
HKD1_k127_7506002_1 Belongs to the N(4) N(6)-methyltransferase family - - - 0.0000000000000000000000000000000000002054 143.0
HKD1_k127_7506645_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 320.0
HKD1_k127_7506645_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000286 278.0
HKD1_k127_7506645_2 acetyltransferase K18566 - - 0.000000000000000000000000000000000007713 154.0
HKD1_k127_7506645_3 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.000000000000000000000000002218 115.0
HKD1_k127_7506645_4 acetyltransferase K18566 - - 0.000000000000000000000003927 115.0
HKD1_k127_7506645_5 ECF sigma factor K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000399 85.0
HKD1_k127_7506645_6 amine dehydrogenase activity - - - 0.0004279 53.0
HKD1_k127_7563457_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 590.0
HKD1_k127_7563457_1 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 347.0
HKD1_k127_7563457_10 PFAM Amino acid-binding ACT - - - 0.0001146 49.0
HKD1_k127_7563457_2 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 354.0
HKD1_k127_7563457_3 N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002982 289.0
HKD1_k127_7563457_4 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001575 274.0
HKD1_k127_7563457_5 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000002689 252.0
HKD1_k127_7563457_6 Sodium/hydrogen exchanger family K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000192 239.0
HKD1_k127_7563457_7 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000005477 218.0
HKD1_k127_7563457_8 AAA domain - - - 0.000000000000000000009582 100.0
HKD1_k127_7563457_9 PFAM Rieske 2Fe-2S domain protein K02636 - 1.10.9.1 0.0000000000000000001167 98.0
HKD1_k127_7621176_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 299.0
HKD1_k127_7621176_1 domain protein - - - 0.00000000000000000000000000002035 125.0
HKD1_k127_7621176_2 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000001211 56.0
HKD1_k127_7625077_0 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 430.0
HKD1_k127_7625077_1 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 369.0
HKD1_k127_7625077_2 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000797 237.0
HKD1_k127_7625077_3 metal-dependent membrane protease K07052 - - 0.0006761 51.0
HKD1_k127_7683692_2 - - - - 0.00000000000000000000000000000000000000000008963 170.0
HKD1_k127_7727826_0 R3H domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 582.0
HKD1_k127_7727826_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 458.0
HKD1_k127_7727826_10 membrane - - - 0.0000000000003339 82.0
HKD1_k127_7727826_11 Belongs to the GbsR family - - - 0.0000000009562 71.0
HKD1_k127_7727826_2 F420-dependent oxidoreductase, G6PDH family K15510 - 1.1.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 459.0
HKD1_k127_7727826_3 FAD dependent oxidoreductase K15736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 392.0
HKD1_k127_7727826_4 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000003421 227.0
HKD1_k127_7727826_5 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000004133 162.0
HKD1_k127_7727826_6 Histidine kinase - - - 0.0000000000000000000000000000000009663 142.0
HKD1_k127_7727826_7 MOSC domain - - - 0.000000000000000000000000000000004485 145.0
HKD1_k127_7727826_8 glyoxalase - - - 0.000000000000000000000001356 113.0
HKD1_k127_7727826_9 - - - - 0.000000000000000002109 98.0
HKD1_k127_7887393_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000001274 200.0
HKD1_k127_7905996_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 515.0
HKD1_k127_7905996_1 Receptor family ligand binding region K01999,K11954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 380.0
HKD1_k127_7905996_10 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000001274 95.0
HKD1_k127_7905996_11 Acyl-ACP thioesterase - - - 0.00000000000009017 84.0
HKD1_k127_7905996_12 Prolyl oligopeptidase family - - - 0.00000000617 69.0
HKD1_k127_7905996_13 Acetyltransferase (GNAT) domain - - - 0.00005652 54.0
HKD1_k127_7905996_2 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 356.0
HKD1_k127_7905996_3 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006664 290.0
HKD1_k127_7905996_4 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001183 286.0
HKD1_k127_7905996_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000095 267.0
HKD1_k127_7905996_7 NYN domain - - - 0.000000000000000000000000000000000006892 156.0
HKD1_k127_7905996_8 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000000000004404 136.0
HKD1_k127_7905996_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000001303 110.0
HKD1_k127_7922892_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 530.0
HKD1_k127_7922892_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 459.0
HKD1_k127_7922892_10 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000095 93.0
HKD1_k127_7922892_11 Luciferase-like monooxygenase - - - 0.0000000001248 69.0
HKD1_k127_7922892_12 lactoylglutathione lyase activity - - - 0.0000005522 59.0
HKD1_k127_7922892_2 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 429.0
HKD1_k127_7922892_3 Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 330.0
HKD1_k127_7922892_4 Protein of unknown function (DUF2652) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 322.0
HKD1_k127_7922892_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000003361 221.0
HKD1_k127_7922892_6 YCII-related domain - - - 0.00000000000000000000000000000000000000001372 155.0
HKD1_k127_7922892_7 Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.0000000000000000000000000000000000001673 155.0
HKD1_k127_7922892_8 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000808 153.0
HKD1_k127_7922892_9 ECF sigma factor K03088 - - 0.000000000000000000000003722 110.0
HKD1_k127_7938248_0 Alpha amylase, catalytic domain - - - 1.084e-309 997.0
HKD1_k127_7938248_1 Aminotransferase class-V - - - 7.096e-242 765.0
HKD1_k127_7938248_10 - - - - 0.0000000000000000000000000000000000000000000000000001485 203.0
HKD1_k127_7938248_11 BtpA family K06971 - - 0.000000000000000000000000000000002957 132.0
HKD1_k127_7938248_12 DNA-binding transcription factor activity K03710 - - 0.0000000000000000000000000000003269 138.0
HKD1_k127_7938248_13 Domain of unknown function (DUF4180) - - - 0.00000000000000000000003773 106.0
HKD1_k127_7938248_14 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000117 100.0
HKD1_k127_7938248_15 carboxylic ester hydrolase activity - - - 0.000000000000001775 89.0
HKD1_k127_7938248_16 PFAM amino acid-binding ACT domain protein - - - 0.000000000000002215 82.0
HKD1_k127_7938248_17 positive regulation of transcription, DNA-templated - - - 0.0000000006833 72.0
HKD1_k127_7938248_2 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 639.0
HKD1_k127_7938248_3 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 529.0
HKD1_k127_7938248_4 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 317.0
HKD1_k127_7938248_5 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 290.0
HKD1_k127_7938248_6 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003381 283.0
HKD1_k127_7938248_7 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001133 289.0
HKD1_k127_7938248_8 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001922 303.0
HKD1_k127_7938248_9 Xylose isomerase-like TIM barrel K21909 - 5.1.3.38 0.00000000000000000000000000000000000000000000000000001488 207.0
HKD1_k127_798875_0 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 324.0
HKD1_k127_798875_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000003369 240.0
HKD1_k127_798875_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000006525 239.0
HKD1_k127_798875_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000002192 229.0
HKD1_k127_798875_4 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000002628 232.0
HKD1_k127_798875_5 Cell division protein FtsQ K03589 - - 0.000000215 61.0
HKD1_k127_822435_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 7.514e-227 719.0
HKD1_k127_822435_1 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000958 452.0
HKD1_k127_822435_10 Major facilitator superfamily K05820 - - 0.000000001026 72.0
HKD1_k127_822435_11 Polyketide cyclase / dehydrase and lipid transport - - - 0.0001043 51.0
HKD1_k127_822435_12 Glycosyltransferase family 87 K13669 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0002845 52.0
HKD1_k127_822435_2 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 361.0
HKD1_k127_822435_3 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009818 344.0
HKD1_k127_822435_4 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000001498 238.0
HKD1_k127_822435_5 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000002866 214.0
HKD1_k127_822435_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000001177 193.0
HKD1_k127_822435_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000067 192.0
HKD1_k127_822435_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000004507 123.0
HKD1_k127_822435_9 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.0000000000000000000001303 103.0
HKD1_k127_887875_0 COG COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit Energy production and conversion K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 430.0
HKD1_k127_887875_1 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 326.0
HKD1_k127_887875_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 323.0
HKD1_k127_887875_3 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000003851 286.0
HKD1_k127_887875_4 PFAM regulatory protein GntR HTH K22293 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003809 262.0
HKD1_k127_887875_5 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000001405 195.0
HKD1_k127_887875_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000001446 97.0
HKD1_k127_887875_7 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000001625 70.0
HKD1_k127_94351_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K20447,K20448 - 1.17.1.5,1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 627.0
HKD1_k127_94351_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 424.0
HKD1_k127_94351_10 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000004239 206.0
HKD1_k127_94351_11 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000004626 220.0
HKD1_k127_94351_12 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000002186 199.0
HKD1_k127_94351_13 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000002258 174.0
HKD1_k127_94351_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000001559 179.0
HKD1_k127_94351_15 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000001688 157.0
HKD1_k127_94351_16 Bacterial-like globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000009297 146.0
HKD1_k127_94351_17 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000002844 147.0
HKD1_k127_94351_19 Bacterial protein of unknown function (DUF881) - - - 0.00000000000000000000000001825 124.0
HKD1_k127_94351_2 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 384.0
HKD1_k127_94351_20 S-layer homology domain - - - 0.00000000000000000001649 104.0
HKD1_k127_94351_21 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000003838 101.0
HKD1_k127_94351_22 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000000001478 94.0
HKD1_k127_94351_23 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000007532 91.0
HKD1_k127_94351_24 Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000001082 94.0
HKD1_k127_94351_25 response regulator, receiver - - - 0.0000000000000006938 94.0
HKD1_k127_94351_27 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000003768 68.0
HKD1_k127_94351_28 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000008343 59.0
HKD1_k127_94351_29 tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 0.00002901 56.0
HKD1_k127_94351_3 PFAM Amidohydrolase 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 359.0
HKD1_k127_94351_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K12953 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 323.0
HKD1_k127_94351_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001933 294.0
HKD1_k127_94351_6 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000004244 241.0
HKD1_k127_94351_7 Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000375 224.0
HKD1_k127_94351_8 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000002972 216.0
HKD1_k127_94351_9 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000007546 219.0
HKD1_k127_950864_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 4.818e-203 672.0
HKD1_k127_950864_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000001308 147.0
HKD1_k127_950864_2 exodeoxyribonuclease I activity - - - 0.000000000000000000000002015 111.0
HKD1_k127_999249_0 Dihydropyrimidinase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 590.0
HKD1_k127_999249_1 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 508.0
HKD1_k127_999249_2 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 437.0
HKD1_k127_999249_3 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 408.0
HKD1_k127_999249_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 367.0
HKD1_k127_999249_5 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 327.0
HKD1_k127_999249_6 inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000002383 199.0
HKD1_k127_999249_7 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000007691 188.0
HKD1_k127_999249_8 Cell wall-associated hydrolase, invasion-associated protein K21471,K21473 GO:0005575,GO:0005576 - 0.0000000000005268 82.0